CN117179965A - Valve prosthesis for treating tricuspid valve - Google Patents

Abstract

The application belongs to the field of medical equipment, and particularly relates to a valve prosthesis for treating tricuspid valve, which comprises a bracket and artificial valve leaflets, wherein the bracket comprises a woven ring and a valve sewing section, the woven ring is connected with the valve sewing section and comprises a ventricular part, an annular part and an atrial part, the atrial part comprises an annular isolation section, a front annular section and a rear annular section, the front annular section and the rear annular section are respectively provided with a clinging structure, and the clinging structures enable the edges of the front annular section and the edges of the rear annular section to be pressed downwards in a proximal direction; the edge of the front annular section and the edge of the rear annular section are in wave shapes, the edge of the middle area of the front annular section and the edge of the middle area of the rear annular section are positioned at wave trough positions, the edge of the end part of the front annular section and the edge of the end part of the rear annular section are positioned at wave crest positions, and when the self valve is opened and closed, the edge height of the middle area of the front annular section and the edge height of the middle area of the rear annular section are always lower than the edge height of the end part of the front annular section and the edge height of the end part of the rear annular section.

Description

Valve prosthesis for treating tricuspid valve

Technical Field

The application belongs to the field of medical appliances, and particularly relates to a valve prosthesis for treating tricuspid valve.

Background

Tricuspid regurgitation is generally caused by pulmonary hypertension, right ventricular enlargement and tricuspid valve annulus expansion, and clinically, the symptoms of right heart failure such as weakness, ascites, edema, liver pain, dyspepsia, anorexia and the like are aggravated after tricuspid valve regurgitation occurs, which are usually manifested by the cause of tricuspid valve regurgitation (left heart failure, pulmonary hypertension and the like). Mild regurgitation of the tricuspid valve has no obvious clinical symptoms, but requires surgical treatment when there is severe regurgitation.

Traditional treatments for mitral and tricuspid valve disease include drug therapy for mild to severe regurgitation, and surgical procedures with corresponding surgical indications. Among other surgical methods, valve replacement and valve repair are also included. In surgical procedures, typical open chest and open heart procedures are too invasive and require the establishment of extracorporeal circulation with a high incidence of complications and risk of infection. Many patients are intolerant of significant surgical risks and can only wait for death without being able to wait.

An adaptive heart valve prosthesis in patent CN106264793B discloses a stent and a prosthetic valve, the stent comprises a leakage-proof ring and a valve sewing section, the leakage-proof ring is connected with the valve sewing section, the prosthetic valve is fixedly connected on the valve sewing section, the valve sewing section is at least partially positioned between the self valve leaflets of a patient, on a cross section perpendicular to the central axis of the prosthetic valve, the cross section area of the valve sewing section is smaller than the cross section area of the self valve annulus of the patient, so that the valve sewing section can not directly radially expand the self valve annulus of the patient, the cross section area of the leakage-proof ring is larger than the cross section area of the self valve annulus of the patient in a free state, and the leakage-proof ring can conform to the uneven contour of the wall of an atrial chamber or the self valve annulus of the patient. The leakage-proof ring in the technical scheme can cover the whole self-body valve ring by means of the larger cross-sectional area, but the peripheral edge of the leakage-proof ring cannot be completely attached to the self-body valve ring, so that perivalvular leakage occurs, and especially the leakage-proof ring is designed in an eccentric structure for adapting to the fixed position of the bracket, so that the areas of a front valve area and a rear valve area corresponding to the leakage-proof ring are larger, the attaching degree of the large-area leakage-proof ring is worse, and serious perivalvular leakage can occur.

Patent CN201922307893.5 discloses an interventional prosthetic heart valve and medical device comprising a valve holder and an anchor, the valve holder having a body section and a skirt section at the inflow end; the body section comprises a plurality of circumferentially arranged supporting parts; at least part of the support extends radially outwards and towards the inflow end; the anchoring part comprises at least two anchoring parts; the anchoring piece is provided with a circular arc-shaped section, an auxiliary section and a connecting part; the free end of the circular arc section is provided with a connecting part which can be detachably connected with the connecting element; the auxiliary section is connected to the circular arc section, and the auxiliary section is arranged on one side, close to the outflow end, of the opposite circular arc section and one side, close to the body, of the auxiliary section and is used for restraining the heart valve of the human body. In the technical scheme, the peripheral edge of the skirt section is provided with a downward turning structure which is used for anchoring the self-body valve ring by matching with the anchoring part, and although the effect of preventing the peripheral leakage of the valve can be achieved to a certain extent, the skirt section is formed by a plurality of main support rods, so that the skirt section cannot be completely attached to the self-body valve ring, or after the skirt section is attached to the self-body valve ring, the gap between the adjacent support rods is larger, so that the heart can be separated from the self-body valve ring in the beating process, and serious peripheral leakage of the valve can occur; the extent of regurgitation is also different between the end regions of the native leaflet and the central region of the leaflet, for example: in the central region of the valve leaflet, the reflux degree is greater than that of the two end regions of the valve leaflet, but in the scheme, the gaps between the adjacent support rods of the skirt edge sections are larger, the support rods do not fall on the valve rings corresponding to the central region of the valve leaflet or only one or two support rods fall on the valve rings corresponding to the central region of the valve leaflet, which can lead to the situation that the skirt edge sections are not tightly attached to the valve rings corresponding to the central region of the valve leaflet, and peripheral leakage of the valve is easy to occur in the continuous blood pumping process of the heart.

Patent cn201910045807.X discloses a prosthetic heart valve comprising at least two valve members, a seal member coated on the valve members, and a sealing structure, wherein a space gap is formed between the valve members coated with the seal member, and an end surface of the sealing structure is closed and is connected with an end of the seal member, so that the space gap forms a closed space. In the technical scheme, the prosthetic valve leaflet and the edge sealing structure can seal the open end which is formed between the two valve components and faces to the blood flow direction, so that the space gap forms a sealed space, and blood stasis is avoided, so that thrombus is formed; however, when the prosthetic valve leaflet is opened, a gap still exists between the prosthetic valve leaflet and the edge sealing structure, so that blood forms vortex between the prosthetic valve leaflet and the edge sealing structure, and the blood is accumulated and cannot be discharged in time, so that thrombus is caused for a long time.

Accordingly, those skilled in the art have focused their efforts on developing a valve prosthesis for treating the tricuspid valve such that the valve prosthesis can be placed against the native annulus after implantation, avoiding paravalvular leakage; meanwhile, blood in the ventricle can be prevented from accumulating between the artificial valve leaflet and the leakage-proof ring, so that thrombus is prevented from being formed.

Content of the application

The technical problem to be solved by the application is to provide a valve prosthesis for treating tricuspid valve, so that the valve prosthesis can be tightly attached to an autologous valve annulus after implantation, and paravalvular leakage is avoided; meanwhile, blood in the ventricle can be prevented from accumulating between the artificial valve leaflet and the leakage-proof ring, so that thrombus is prevented from being formed.

In order to solve the technical problems, the application is solved by the following technical scheme:

according to one aspect of the application, a valve prosthesis for treating a tricuspid valve comprises a stent and artificial valve leaflets, wherein the stent comprises a braided ring and a valve sewing section, the braided ring is connected with the valve sewing section, the artificial valve leaflets are fixed in the valve sewing section, the cross-sectional area of the braided ring is larger than that of an autologous valve ring, the braided ring comprises a ventricle part, an annular part and an atrium part, the atrium part comprises an annular isolation section, an anterior annular section and a posterior annular section, and the anterior annular section and the posterior annular section are respectively provided with a clinging structure, and the clinging structure enables edges of the anterior annular section and edges of the posterior annular section to be pressed downwards in a proximal direction; after the front valve ring section and the rear valve ring section of the woven ring are spread in a flat mode, the edge of the front valve ring section and the edge of the rear valve ring section are in wave shapes, the edge of the middle area of the front valve ring section and the edge of the middle area of the rear valve ring section are in wave trough positions, the edge of the end part of the front valve ring section and the edge of the end part of the rear valve ring section are in wave crest positions, when the valve prosthesis is installed in place and the self valve is opened and closed, the edge height of the middle area of the front valve ring section and the edge height of the middle area of the rear valve ring section are always lower than the edge height of the end part of the front valve ring section and the edge height of the end part of the rear valve ring section, and the edge of the atrial part is always clung to the self valve ring or atrial tissue.

The aim of the application can be further realized by the following technical scheme:

according to an embodiment, the woven ring comprises a supporting framework and a fabric layer, the supporting framework is composed of a plurality of supporting units, the adjacent supporting units are interwoven at the position of an atrial part, and the self valve is in a process of opening and closing, the self valve ring is in a height fluctuation in the axial direction, and the edge part of the woven ring is always clung to atrial tissues.

According to an embodiment, the valve prosthesis further comprises a fixation device, one end of which is connected to the valve sewing section, and an anchor, by means of which the other end of the fixation device is fixed to the ventricular septum tissue.

According to an embodiment, the abutment structure abuts the native valve annulus, and the edge of the atrial portion abuts the atrial wall of the patient, after implantation of the valve prosthesis; the cross section area of the woven ring is larger than that of the self-body valve ring, the close-fitting structure is attached to the valve ring, and meanwhile, the edge of the atrial part is attached to the atrial wall of a patient, so that the tightness of the woven ring can be better ensured.

According to an embodiment, the cross-sectional area of the annuloplasty ring segments is smaller than the cross-sectional area of the anterior annuloplasty ring segments and the cross-sectional area of the posterior annuloplasty ring segments; the fixation device is fixed to the compartment by an anchor, the compartment being positioned adjacent to the annuloplasty ring segment, and the valve sewing segment is positioned adjacent to the annuloplasty ring segment in order to ensure stability of the valve sewing segment.

According to an embodiment, the stiffness of the annuloplasty ring segment is less than both the stiffness of the anterior annulus segment and the stiffness of the posterior annulus segment; the position of the annular segment is close to the ventricular septum tissue, and the fixing device is fixed on the ventricular septum through the anchoring piece, so that the annular segment has smaller rigidity strength, the damage to the tissue at the annular segment after implantation is avoided, and the annular segment can be attached to the tissue at the annular segment more.

According to an embodiment, the density of the support units of the annuloplasty ring segments is less than the density of the support units of the anterior and posterior annulus segments.

According to one embodiment, the support frame is preferably made of a metal memory alloy material, for example: nickel-titanium alloy; the supporting framework is composed of dense supporting units, and adjacent supporting units are interwoven at the positions of the atrial parts, so that the atrial parts of the woven ring can cover and cling to each position of the self-body valve ring in an all-around manner, and the situation that gaps between adjacent supporting units are too large to cling to the self-body valve ring is avoided.

According to an embodiment, the abutment structure is arranged in an arc-shaped configuration and, after implantation of the valve prosthesis, the abutment structure covers or abuts against the native valve annulus.

According to an embodiment, the ventricular part comprises an edge provided with a notch, the edge is fixedly connected to the valve sewing section, and the notch of the edge is arranged on the valve sewing section and is opposite to the active area of the artificial valve leaflet; blood located between the prosthetic leaflet and the ventricular portion flows out through the gap of the rim when the valve prosthesis is in an open state.

According to an embodiment, the artificial leaflet is fixed in the valve sewing section by a flexible thread, the artificial leaflet comprising a fixed portion and a moving portion; and the outline formed at the junction of the fixed part and the moving part is similar to the outline of the edge notch.

According to an embodiment, the movement portion is disposed directly opposite to the notch of the edge, and the ventricular portion and the movement portion do not overlap on a cross-section of the central axis of the valve sewing section, so that blood between the artificial leaflet and the ventricular portion flows out through the notch of the edge when the valve prosthesis is in an open state; the design has the advantages that: when the moving part of the artificial valve blade is opened, blood at the periphery of the artificial valve blade is extruded by the direction of the inner wall of the artificial valve She Xiangxin chamber, and the edge of the ventricular segment can not block the blood, so that the blood can flow out from a notch at the edge quickly, and blood stasis and thrombus after long-term implantation are avoided.

According to an embodiment, the edge of the ventricular part is provided with three continuous notches, the edge of the ventricular part has a substantially wavy structure, and the notches of the edge are opposite to the moving part of the artificial valve leaflet; the design has the advantages that: when the artificial valve leaflet is in an open state (namely, the center of the valve sewing section moves towards the inner surface of the valve sewing section), blood around the outer surface of the artificial valve leaflet can flow out through the gaps at the edges, so that the blood is prevented from staying between the periphery of the artificial valve leaflet and the woven ring to form vortex, and thrombus occurs for a long time.

Compared with the prior art, the application has the advantages that:

1. when the self valve is opened and closed, the change (movement stroke) of the middle area of the self valve leaflet before and after opening and closing is the largest, especially the fluctuation change of the axial height is very large, so that the pressure of the blood reflux of the valve annulus part corresponding to the middle area of the self valve leaflet is the largest, the leak-proof ring in the prior art can not be always attached to the self valve annulus tissue, when the self valve is closed, the fluctuation stroke of the valve annulus part corresponding to the middle area of the self valve leaflet is the largest, the gap between the leak-proof ring and the self valve annulus is increased, and the corresponding blood reflux degree is the most serious. The blood reflux is avoided, simultaneously, the front annular section and the rear annular section are gradually pressed downwards from two ends to the middle position, so that the position with the largest pressing amplitude of the front annular section and the rear annular section is just positioned at the annular section part corresponding to the middle area of the self-body valve, when the self-body valve (especially the middle area) expands and fluctuates due to the valve in the opening and closing process, the edge height of the middle area of the front annular section and the edge height of the middle area of the rear annular section are always lower than the edge height of the end part of the front annular section and the edge height of the end part of the rear annular section, the atrial part of the woven ring can always cover and cling to the self-body valve ring and atrial tissues, and the self-adapting deformation is synchronously made along with the change of the self-body valve ring, so that the paravalvular leakage is effectively avoided.

2. In an embodiment of the application, the stiffness of the annuloplasty ring segments is less than the stiffness of the anterior and posterior annulus segments, as opposed to the prior art; the position of the annular segment is close to the ventricular septum tissue, and the fixing device is fixed on the ventricular septum through the anchoring piece, so that the annular segment has smaller rigidity strength, the damage to the tissue at the annular segment after implantation is avoided, and the annular segment can be attached to the tissue at the annular segment more.

3. In an embodiment of the application, in contrast to the prior art, the ventricular segment does not overlap the moving part in a cross-section of the central axis of the sewing segment of the valve; the design has the advantages that: when the moving part of the artificial valve blade is opened, blood at the periphery of the artificial valve blade is extruded by the direction of the inner wall of the artificial valve She Xiangxin chamber, and the edge of the ventricular segment can not block the blood, so that the blood can flow out from a notch at the edge quickly, and blood stasis and thrombus after long-term implantation are avoided.

4. In the prior art, in order to avoid the problem of paravalvular leakage, the leakage-proof ring needs to be extended from the annular part of an atrium to a self-body annular or a ventricle, so that when the valve is closed, blood in the atrium or the ventricle of the valve can be effectively prevented from penetrating into a gap between the valve prosthesis and the self-body annular to cause serious paravalvular leakage; the artificial valve leaves and the leakage-proof ring are separated, when the artificial valve leaves are opened, the blood can not be discharged in time, and thrombus can be formed after long-term implantation; in one embodiment of the application, the part of the woven ring at the ventricular section is provided with the edge, the edge is provided with the notch, and the notch is opposite to the moving part of the artificial valve, so that when the artificial valve is opened, blood between the ventricular section of the woven ring and the artificial valve can be rapidly discharged through the notch, blood accumulation is avoided, and meanwhile, vortex formation of part of blood between the ventricular section and the artificial valve is avoided, and serious thrombus is generated for a long time.

Embodiments of the application are capable of other advantageous technical effects not listed one after another, which may be described in part below and which will be anticipated and understood by those skilled in the art after reading the present application.

Drawings

The above-mentioned and other features and advantages of these embodiments, and the manner of attaining them, will become more apparent and the embodiments of the application will be better understood by reference to the following description taken in conjunction with the accompanying drawings, wherein:

fig. 1 a-1 c are schematic views of the overall structure of a valve prosthesis according to the application.

Fig. 2a to 2e are schematic structural views of an atrial portion according to the present application.

Fig. 3a to 3d are schematic structural views of an artificial leaflet and a ventricular part according to the present application.

The names of the parts indicated by the numerals in the drawings are as follows: 1-stent, 11-woven ring, 111-ventricular part, 1111-rim, 1112-gap, 112-annulus part, 113-atrial part, 1131-annuloplasty ring segment, 1132-anterior annulus segment, 1133-posterior annulus segment, 1134-cling structure, 114-support frame, 1141-support unit, 115-fabric layer, 12-valve sewing segment, 13-fixture, 14-anchor, 2-artificial leaflet, 21-fixture, 22-motion part.

Detailed Description

The present application will be described in further detail with reference to the accompanying drawings and examples.

The proximal end refers to an end near an operator, and the distal end refers to an end far away from the operator.

Specific examples:

the details of one or more embodiments of the application are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the application will be apparent from the description and drawings, and from the claims.

It is to be understood that the illustrated and described embodiments are not limited in application to the details of construction and the arrangement of components set forth in the following description or illustrated in the drawings. The illustrated embodiments may be other embodiments and can be implemented or performed in various ways. Examples are provided by way of explanation, not limitation, of the disclosed embodiments. Indeed, it will be apparent to those skilled in the art that various modifications and variations can be made to the various embodiments of the application without departing from the scope or spirit of the disclosure. For example, features illustrated or described as part of one embodiment can be used with another embodiment to yield still a further embodiment. Accordingly, the present disclosure is intended to cover such modifications and variations as fall within the scope of the appended claims and their equivalents.

Also, it is to be understood that the phraseology and terminology used herein is for the purpose of description and should not be regarded as limiting. The use of "including," "comprising," or "having" and variations thereof herein is meant to encompass the items listed thereafter and equivalents thereof as well as additional items.

The application will be described in more detail below with reference to different embodiments and examples of several aspects of the application.

In the present application, "proximal" refers to the end proximal to the apex of the heart and "distal" refers to the end distal to the apex of the heart.

Example 1

The tricuspid valve of the human heart has anterior, posterior and diaphragmatic leaflets. The anterior leaflet, the posterior leaflet, and the diaphragmatic leaflet are in a closed state when the heart contracts, and valve regurgitation occurs when one of the anterior leaflet, the posterior leaflet, and the diaphragmatic leaflet fails to close normally in the closed state.

When the self-valve is opened and closed, the change (movement stroke) of the middle area of the self-valve leaflet before and after the opening and closing is the largest, so that the pressure of the blood reflux of the valve annulus part corresponding to the middle area of the self-valve leaflet is the largest.

According to one example, a valve prosthesis for treating tricuspid valve, comprising a stent 1 and a prosthetic leaflet 2, the stent 1 comprising a woven ring 11, a valve sewing section 12, a securing means 13 and an anchor 14, as shown in fig. 1a and 1b, one end of the securing means 13 being connected to the valve sewing section 12, the other end of the securing means 13 being secured to the ventricular septum tissue by the anchor 14, the woven ring 11 being connected to the valve sewing section 12, the prosthetic leaflet 2 being secured within the valve sewing section 12, the woven ring 11 having a cross-sectional area greater than that of the native valve ring, the woven ring 11 comprising a ventricular part 111, an annular part 112 and an atrial part 113, the atrial part 113 comprising a septal ring section 1131, a front annular section 1132 and a rear annular section 1133, both provided with a clinging structure 1134, the clinging structure 1134 enabling the edges 1111 and the rear annular section 1132 to bear against the peripheral edge 1111 of the annular ring 1111 and the peripheral edge 113 as shown in fig. 2b, and the peripheral edge 1111 can bear against the peripheral edge 1111 and the annular part 113 as shown in the circumferential direction of the annular ring 11; and, after the anterior and posterior annular segments 1132, 1133 of the braided ring 11 are tiled, as shown in fig. 1 c; the edge 1111 of the anterior annulus section 1132 and the edge 1111 of the posterior annulus section 1133 are in a wave form, and the edge 1111 of the middle region of the anterior annulus section 1132 and the edge 1111 of the middle region of the posterior annulus section 1133 are in a wave trough position, and the edge 1111 of the end of the anterior annulus section 1132 and the edge 1111 of the end of the posterior annulus section 1133 are in a wave crest position; the front annular segment 1132 and the rear annular segment 1133 are gradually pressed down from two ends to the middle position, so that the position with the largest pressing-down amplitude of the front annular segment 1132 and the rear annular segment 1133 is just at the part of the annular segment corresponding to the middle area of the self-valve leaflet, when the self-valve is opened and closed after the valve prosthesis is installed in place, the height of the edge 1111 of the middle area of the front annular segment 1111 and the height of the edge 1111 of the middle area of the rear annular segment 1122 are always lower than the height of the edge of the end part of the front annular segment 1111 and the height of the edge of the end part of the rear annular segment 1133, and the edge of the atrial part 113 is always clung to the self-valve annulus or the atrial tissue.

In this embodiment, the woven ring 11 includes a supporting framework 114 and a fabric layer 115, as shown in fig. 2e, the supporting framework 114 is composed of a plurality of supporting units 1141, and the self-valve ring is fluctuated in the axial direction during the opening and closing process, and the edge portion of the woven ring 11 is always clung to the atrial tissue.

In this embodiment, the abutment 1134 abuts against the native valve annulus and the edge 1111 of the atrial portion 113 abuts against the atrial wall of the patient after the implantation of the valve prosthesis; the cross-sectional area of the braided ring 11 is greater than the cross-sectional area of the native annulus, and the abutment of the structure 1134 against the annulus, while the edge 1111 of the atrial portion 113 abuts against the patient's atrial wall, better ensuring the tightness of the braided ring 11.

In this embodiment, the cross-sectional area of the annuloplasty ring segment 1131 is smaller than the cross-sectional area of the anterior annuloplasty ring segment 1132 and the cross-sectional area of the posterior annuloplasty ring segment 1133, as shown in fig. 2 d; the fixation device 13 is fixed to the compartment by an anchor 14, which is located close to the annuloplasty ring segment 1131, whereas the valve sewing segment 12 is located close to the annuloplasty ring segment 1131 in order to ensure stability of the valve sewing segment 12.

In this embodiment, the stiffness of the annuloplasty ring segment 1131 is less than the stiffness of the anterior annuloplasty ring segment 1132 and the stiffness of the posterior annuloplasty ring segment 1133; the positioning of the annuloplasty ring segment 1131 is close to the ventricular septum tissue, and because the fixation device 13 is fixed on the ventricular septum by the anchor 14, the annuloplasty ring segment 1131 has smaller rigidity, thereby avoiding damage to the tissue at the annulus after implantation, and simultaneously enabling the annuloplasty ring segment 1131 to be more attached to the tissue at the annulus.

In this embodiment, the density of the support elements 1141 of the annuloplasty ring segment 1131 is less than the density of the support elements 1141 of the anterior and posterior annulus segments 1132, 1133.

In this embodiment, the supporting frame 114 is preferably made of a metal memory alloy material, for example: nickel-titanium alloy; the support frame 114 is composed of closely spaced support elements 1141, and adjacent support elements 1141 are interwoven at the atrial portion 113 positions, which allows the atrial portion 113 of the braided ring 11 to cover and abut against every position of the native valve annulus in all aspects, avoiding that the gaps between adjacent support elements 1141 are too large to abut against the native valve annulus.

In this embodiment, the attachment structure 1134 is configured in an arc shape, and the attachment structure 1134 covers or attaches to the native valve annulus after the valve prosthesis is implanted.

In this embodiment, the ventricular part 111 includes an edge 1111 provided with a notch 1112, as shown in fig. 2b, the edge 1111 is fixedly connected to the valve sewing section 12, and the notch 1112 of the edge 1111 is disposed on the valve sewing section 12 and faces the active area of the artificial leaflet 2; when the valve prosthesis is in the open state, blood located between the artificial leaflet 2 and the ventricular part 111 flows out through the notch 1112 of the edge 1111.

In this embodiment, the artificial leaflet 2 is fixed in the valve sewing section 12 by a flexible thread, and the artificial leaflet 2 includes a fixed portion 21 and a moving portion 22, as shown in fig. 3a to 3 c; and, the outline formed at the juncture of the fixed part 21 and the moving part 22 is similar to the outline of the notch 1112 of the edge 1111.

In this embodiment, the moving part 22 is disposed opposite to the notch 1112 of the edge 1111, and the ventricular part 111 and the moving part 22 do not overlap on the cross section of the central axis of the valve sewing section 12, so that when the valve prosthesis is in the open state, blood between the artificial leaflet 2 and the ventricular part 111 flows out through the notch 1112 of the edge 1111; the design has the advantages that: when the moving part 22 of the artificial valve leaflet 2 is opened, the blood at the periphery of the artificial valve leaflet 2 is extruded by the artificial valve leaflet 2 towards the indoor wall direction, and the edge 1111 of the ventricular segment can not block the blood, so that the blood can flow out of the notch 1112 of the edge 1111 quickly, and blood stasis and thrombus after long-term implantation are avoided.

In this embodiment, the edge 1111 of the ventricular part 111 is provided with three continuous notches 1112, as shown in fig. 3d, the edge 1111 of the ventricular part 111 has a substantially wavy structure, and the notches 1112 of the edge 1111 are opposite to the moving part 22 of the artificial valve leaflet 2; the design has the advantages that: when the artificial valve leaflet 2 is in an open state (i.e. moving from the center of the valve sewing section 12 to the inner surface of the valve sewing section 12), blood around the outer surface of the artificial valve leaflet 2 can flow out through the notch 1112 of the edge 1111, so that the blood is prevented from staying and forming vortex between the outer periphery of the artificial valve leaflet 2 and the woven ring 11, and thrombus occurs for a long time.

The foregoing is merely exemplary of the present application, and those skilled in the art should not be considered as limiting the application, since modifications may be made in the specific embodiments and application scope of the application in light of the teachings of the present application.

Claims (10)

1. A valve prosthesis for treating tricuspid valve, comprising a support and artificial valve leaflets, wherein the support comprises a braiding ring and a valve sewing section, the braiding ring is connected with the valve sewing section, the artificial valve leaflets are fixed in the valve sewing section, the cross-sectional area of the braiding ring is larger than that of a native valve annulus, and the braiding ring comprises a ventricular part, an annular part and an atrial part, and is characterized in that: the atrial part comprises an annular isolation section, an anterior annular section and a posterior annular section, wherein the anterior annular section and the posterior annular section are respectively provided with a clinging structure, and the clinging structures enable the edges of the anterior annular section and the edges of the posterior annular section to be pressed downwards in the proximal direction; after the front valve ring section and the rear valve ring section of the woven ring are spread in a flat mode, the edge of the front valve ring section and the edge of the rear valve ring section are in wave shapes, the edge of the middle area of the front valve ring section and the edge of the middle area of the rear valve ring section are in wave trough positions, the edge of the end part of the front valve ring section and the edge of the end part of the rear valve ring section are in wave crest positions, when the valve prosthesis is installed in place and the self valve is opened and closed, the edge height of the middle area of the front valve ring section is always lower than the edge height of the end part of the front valve ring section, the edge height of the middle area of the rear valve ring section is always lower than the edge height of the end part of the rear valve ring section, and the edge of the atrium is always clung to the self valve ring or atrial tissue.

2. A valve prosthesis for treating a tricuspid valve according to claim 1, wherein: the woven ring comprises a supporting framework and a fabric layer, wherein the supporting framework is composed of a plurality of supporting units, the adjacent supporting units are interwoven at the position of an atrial part, the self valve is in the opening and closing process, the self valve ring is in the axial height fluctuation, and the edge part of the woven ring is always clung to atrial tissues.

3. A valve prosthesis for treating a tricuspid valve according to claim 1, wherein: the valve prosthesis further comprises a fixing device and an anchor, one end of the fixing device is connected with the valve sewing section, and the other end of the fixing device is fixed on the ventricular septum tissue through the anchor.

4. A valve prosthesis for treating a tricuspid valve according to claim 1, wherein: the cross-sectional area of the annuloplasty ring segments is smaller than the cross-sectional area of the anterior annuloplasty ring segments and the cross-sectional area of the posterior annuloplasty ring segments.

5. A valve prosthesis for treating a tricuspid valve according to claim 4, wherein: the stiffness of the annuloplasty ring segments is less than the stiffness of the anterior annulus segments and the stiffness of the posterior annulus segments.

6. A valve prosthesis for treating a tricuspid valve according to claim 4, wherein: the support elements of the annuloplasty ring segments have a density less than the density of the support elements of the anterior and posterior annulus segments.

7. A valve prosthesis for treating a tricuspid valve according to claim 1, wherein: the cling structure is configured in an arcuate configuration and, after implantation of the valve prosthesis, the cling structure overlies or conforms to the native annulus.

8. A valve prosthesis for treating a tricuspid valve according to claim 1, wherein: the ventricular part comprises an edge provided with a notch, the edge is fixedly connected to the valve sewing section, and the notch of the edge is arranged on the valve sewing section and is opposite to the movable area of the artificial valve leaflet; blood located between the prosthetic leaflet and the ventricular portion flows out through the gap of the rim when the valve prosthesis is in an open state.

9. A valve prosthesis for treating a tricuspid valve according to claim 8, wherein: the artificial valve leaflet is fixed in the valve sewing section through a flexible line, and comprises a fixed part and a moving part; and the outline formed at the junction of the fixed part and the moving part is similar to the outline of the edge notch.

10. A valve prosthesis for treating a tricuspid valve according to claim 9, wherein: the movement part is arranged right opposite to the notch of the edge, and on the section of the central axis of the valve sewing section, the ventricular part and the movement part are not overlapped, so that when the valve prosthesis is in an open state, blood between the artificial valve leaflet and the ventricular part flows out through the notch of the edge.