CN117122468B - Cornea stroma lens ring producer - Google Patents
Cornea stroma lens ring producer Download PDFInfo
- Publication number
- CN117122468B CN117122468B CN202311015742.7A CN202311015742A CN117122468B CN 117122468 B CN117122468 B CN 117122468B CN 202311015742 A CN202311015742 A CN 202311015742A CN 117122468 B CN117122468 B CN 117122468B
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- cutter
- lens
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- diameter
- cutter handle
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- 210000004087 cornea Anatomy 0.000 title claims abstract description 37
- 210000003683 corneal stroma Anatomy 0.000 claims abstract description 14
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 239000011148 porous material Substances 0.000 claims description 5
- 239000010437 gem Substances 0.000 claims description 4
- 229910001751 gemstone Inorganic materials 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 229910001220 stainless steel Inorganic materials 0.000 claims description 4
- 239000010935 stainless steel Substances 0.000 claims description 4
- 239000004519 grease Substances 0.000 claims description 3
- 238000005520 cutting process Methods 0.000 abstract description 16
- 201000002287 Keratoconus Diseases 0.000 description 13
- 239000011159 matrix material Substances 0.000 description 6
- 201000010041 presbyopia Diseases 0.000 description 6
- 238000001356 surgical procedure Methods 0.000 description 6
- 238000004132 cross linking Methods 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000003754 machining Methods 0.000 description 3
- 206010064996 Ulcerative keratitis Diseases 0.000 description 2
- 201000007717 corneal ulcer Diseases 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000000750 progressive effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 206010020675 Hypermetropia Diseases 0.000 description 1
- 229940124091 Keratolytic Drugs 0.000 description 1
- 208000034693 Laceration Diseases 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 201000006318 hyperopia Diseases 0.000 description 1
- 230000004305 hyperopia Effects 0.000 description 1
- 230000001530 keratinolytic effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000001491 myopia Diseases 0.000 description 1
- 230000004379 myopia Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
- B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
- B26D1/04—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member
- B26D1/06—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a linearly-movable cutting member wherein the cutting member reciprocates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
- A61F2009/00872—Cornea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00885—Methods or devices for eye surgery using laser for treating a particular disease
- A61F2009/00893—Keratoconus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
Abstract
The invention discloses a cornea stroma lens ring maker, which comprises a base, a casing and a ring cutter; the base is used for containing the lens and comprises a round fixed base, a cylindrical bearing part is arranged in the center of the round fixed base, and a groove used for containing and fixing the lens is arranged in the center of the top end of the bearing part; the casing comprises a guide part positioned above and a positioning part positioned below the guide part, the guide part and the positioning part are hollow cylinders, the outer diameters of the guide part and the positioning part are the same, the inner diameters are different, the annular cutter comprises a cutting edge and a cutter handle, the cutting edge is annular and is arranged below the cutter handle, the cutter handle comprises a cylindrical cutter handle body and a holding part of the cutter handle body, the positioning part of the casing ensures that the casing is positioned and fixed with the base, and the guide part ensures that the annular cutter cuts the corneal stroma lens vertically downwards; the circular cutting is easy to load and learn, and the cornea stroma lenses with different shapes and sizes can be obtained according to the requirements.
Description
Technical Field
The invention relates to the fields of clinical ophthalmology, cornea refractive surgery, presbyopia correction surgery, keratoconus surgery and the like, in particular to a cornea matrix lens ring making device.
Background
Femtosecond laser small incision corneal stroma lens extraction (small incision lenticule extraction, SMILE) is one of the mainstream surgical modes of the current cornea refractive surgery. With the great popularity of SMILE surgery, the lens removed as a good biomaterial can be used for correcting hyperopia and presbyopia, treating keratoconus, corneal dilatation and other membranous defect diseases, and repairing corneal ulcer perforation and corneal lacerations.
For example, keratoconus is a progressive keratolytic disorder, and corneal cross-linking is currently the most effective way to treat progressive keratoconus, and can increase the biomechanical stability of keratoconus, thereby controlling the developing keratoconus. The present literature reports that crosslinking is safe for keratoconus with a corneal thickness greater than 400 μm. When the cornea thickness is well below this thickness value, the risk of cornea crosslinking techniques will increase greatly.
The cornea of a patient becomes thinner gradually with the progress of the disease, the thickness of the cornea is far thinner than 400 mu m when a part of patients visit, and the keratomatrix lens implantation combined cornea crosslinking technology is often used for keratoconus patients with thinner cornea, namely, the first step of cornea matrix lens implantation is performed to increase the thickness of the cornea, and the second step of cornea crosslinking is performed.
Although the convex lens type cornea stroma lens is directly implanted between keratoconus layers to achieve the aim of increasing the cornea thickness, the cornea curvature after operation can be increased, so that the difficulty of refractive reconstruction after keratoconus operation is increased. And if the lens is made in a ring shape, the increase of the curvature of the cornea after operation can be avoided. At present, the domestic cornea stroma lens is from myopia SMILE operation (hyperopic SMILE is not yet marketed), and the cornea stroma lens is a convex lens with the diameter of about 6.5mm. Some applications may be whole-piece implants, such as correcting presbyopia, others require cutting the corneal stroma lens to the desired shape and size, such as cutting the lens to the corresponding size to repair corneal ulcer perforations, etc., making the lens 1mm in size implants may treat presbyopia, making the lens annular to treat keratoconus, etc.
However, no special equipment is used for cutting the cornea stroma lens at present, the cutting is time-consuming, and the error of the lens after cutting is larger, so that the treatment effect is affected.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a cornea stroma lens ring maker.
The complete technical scheme of the invention comprises the following steps:
a cornea stroma lens ring maker, which comprises a base, a casing and a ring cutter;
the base is used for containing lenses and comprises a circular fixing base positioned at the lowest part, a cylindrical bearing part is arranged in the center of the circular fixing base, a groove with the diameter of 6.5mm is arranged in the center of the top end of the bearing part, and the groove is used for containing and fixing the lenses;
the shell is used for connecting the base and the ring cutter and comprises a guide part positioned above and a positioning part positioned below the guide part, the guide part and the positioning part are hollow cylinders, the outer diameters of the guide part and the positioning part are the same, the inner diameters are different, the inner diameter of the positioning part is not smaller than the outer diameter of the bearing part, the inner diameter of the guide part is not smaller than the outer diameter of the cutter handle,
the annular cutting edge is annular and is arranged below the cutter handle, the cutter handle comprises a cylindrical cutter handle body and a holding part of the cutter handle body, the positioning part of the casing ensures that the casing is positioned and fixed with the base, and the guiding part ensures that the annular cutting edge vertically cuts the cornea stroma lens downwards.
Further, when the corneal stroma lens is manufactured, the cutter handle body is positioned in the guiding part of the sleeve, and the holding part is positioned above the guiding part of the sleeve.
Further, when the cornea stroma lens is manufactured, the inner wall of the positioning part is attached to the outer wall of the bearing part.
Further, the diameter of the base is 22.5mm, the diameter of the cylindrical bearing part is 10.5mm, the height of the cylindrical bearing part is 10mm, and the depth of the groove in the center of the top end of the bearing part is 0.5mm.
Further, the inner diameter of the positioning part is 10.6mm, and the inner diameter of the guiding part is 6.5mm.
Further, the diameter of the cutter blade is 1mm and 3mm, the caliber of 1mm is used for manufacturing a 1mm lens, the caliber of 3mm is used for manufacturing a 3mm lens and an annular lens with the inner diameter of 3mm, and the cutter handle body is cylindrical and has the diameter of 6.5mm.
Further, the blade is 3mm high.
Further, the knife edge material is artificial precious stone, the knife handle body is stainless steel, and the surface of the holding part is frosted.
Further, a corneal stroma lens ring maker comprises a base, a casing and a ring cutter; the casing comprises a guide part and a positioning part, and the annular cutter comprises a cutting edge and a cutter handle; the inner diameter of the guiding part is gradually reduced from top to bottom, and grease is arranged between the sleeve shell and the cutter handle body to realize an oil seal. An exhaust channel is formed between the positioning part of the casing and the bearing part of the base, and a circle of porous material is arranged in an annular gap between the positioning part and the circular fixed base. When the cutter handle body moves downwards, gas can only be discharged from the exhaust channel due to the action of the oil seal, and the air pressure in the groove and the exhaust channel is gradually increased in the moving process of the cutter handle body due to the gradual reduction of the inner diameter of the guide part from top to bottom and the effect of the porous material in blocking the gas discharge, so that the cornea matrix lens which is not completely flattened is completely unfolded under the pressure action.
The method for cutting the corneal stroma lens by using the maker comprises the steps of performing SMILE operation to obtain the corneal stroma lens, placing the lens in a base groove with the right side upwards, flattening and centering, and sucking excessive water by using an operation sponge; the annular cutter is arranged in the casing, sleeved on the base cylinder and vertically pressed downwards against the head of the cutter handle, so that a corneal stroma lens sheet with the diameter of 1mm (used for presbyopia operation) or an annular lens with the inner diameter of 3mm and the outer diameter of 6.5mm (used for keratoconus) can be obtained.
The invention has the advantages compared with the prior art that:
the diameter of the cornea stroma lens from the SMILE is 6.5mm generally, and the technology designs a groove with the diameter of 6.5mm in the center of the base, so that the isolated cornea stroma lens is easily laid on the base in a centered manner, and accurate centering and positioning are realized; marking is not needed, and marking pen errors are avoided; the circular cutting process has simple loading and easy learning, can obtain cornea stroma lenses (annular and circular) with different shapes and sizes according to the needs, has simple operation and reduces operation errors. The material of the invention is stainless steel and artificial precious stone, and can be disinfected repeatedly.
Drawings
Fig. 1 is a schematic view of a base.
Fig. 2 is a sectional view of the case.
Fig. 3 is a schematic perspective view of the ring cutter.
Fig. 4 is an assembled cross-sectional view.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the examples of the present application, and it is obvious that the described embodiments are merely examples and are not intended to limit the present application.
As shown in fig. 1 to 4, the present invention discloses a corneal stroma lens ring maker, which comprises a base 1, a case 2, and a ring cutter 3.
The base is used for holding lenses, and as shown in fig. 1, the lens comprises a circular fixed base 11 positioned at the lowest part, the diameter is 22.5mm, a cylindrical bearing part 12 is arranged at the center of the base, the diameter of the cylindrical bearing part is 10.5mm, the height of the cylindrical bearing part is 10mm, a groove 13 with the diameter of 6.5mm is formed in the center of the top end of the bearing part, and the depth of the groove is 0.5mm.
The casing is connected with the base and the ring cutter, supports and fixes the function, guarantees that the ring cutter cuts the cornea matrix lens downwards perpendicularly, and as shown in fig. 2, the casing is roughly in a barrel shape, and the casing comprises a guide part 21 positioned above and a positioning part 22 positioned below the guide part, wherein the guide part and the positioning part are hollow barrel-shaped, the outer diameters of the guide part and the positioning part are the same, the inner diameters are different, the outer diameter is 11mm, the positioning part matched with the bearing part of the base for positioning is arranged below the casing, the inner diameter of the positioning part is 10.6mm, the inner diameter of the guide part 21 is designed to have two structures, the first structure adopts a uniform inner diameter of 6.5mm, the second structure is that the inner diameter is gradually reduced from top to bottom, and the inner diameter of the smallest part is 6.5mm.
As shown in FIG. 3, the annular cutter is divided into a cutting edge 31 and a cutter handle, the cutting edge is 3mm high, the diameter is divided into two types of 1mm and 3mm, the aperture of 1mm is used for manufacturing a lens of 1mm, the aperture of 3mm is used for manufacturing a lens of 3mm and an annular lens of 3mm in inner diameter, the material is artificial precious stone, the annular cutter is sharp, the cornea matrix lens can be easily and rapidly cut, the cutter handle is made of stainless steel and comprises a cylindrical cutter handle body 32 and a handle body holding part 33, the handle body is cylindrical, the diameter is 6.45mm, the surface is smooth, the cutter handle can easily move up and down during operation, the surface of the handle head holding part 33 is frosted, and when the lens is convenient to cut, the stress area is increased, so that annular cutting is easier.
The use flow is as follows: SMILE surgery obtains a stromal corneal lens, places the lens right side up in a recess in the base, flattens and centers, and aspirates excess moisture with a surgical sponge. The annular cutter is arranged in the casing, sleeved on the base cylinder and vertically pressed downwards against the head of the cutter handle, so that a corneal stroma lens sheet with the diameter of 1mm (used for presbyopia operation) or an annular lens with the inner diameter of 3mm and the outer diameter of 6.5mm (used for keratoconus) can be obtained.
In addition, since the corneal stroma lens is a part of biological tissue scanned from the stroma of the anterior portion of the cornea by the femtosecond laser, is thin and very soft, although it is generally developed by means of physiological saline at the time of reworking the lens, it still encounters the situation that wrinkling or incomplete flattening occurs due to the excessive thinness of the lens at the time of actual machining, and affects the machining accuracy, through research, a solution has been devised to solve this problem, i.e., the inner diameter of the guide portion 21 is designed to be gradually reduced from top to bottom, the upper end is larger, grease is applied between the case and the shank body 32 at the time of machining to realize oil sealing, and an exhaust passage 4 is formed between the positioning portion 21 of the case and the bearing portion of the base, and the annular gap between the positioning portion and the circular fixing base 11 is provided with a ring of porous material, as shown in fig. 4. When the handle body moves downwards, gas can only be discharged from the exhaust channel due to the action of the oil seal, and the inner diameter of the guide part 21 gradually reduces from top to bottom, and the porous material blocks the gas from being discharged. The air pressure in the groove 13 and the exhaust channel is gradually increased in the moving process of the cutter handle body, so that the cornea stroma lens which is not completely flattened is completely unfolded under the action of pressure, and the accurate processing shape is obtained. When the structure is designed and processed, the size of each part and the descending speed of the annular cutter are considered, so that proper positive pressure is formed at the groove, the cornea matrix lens can be ensured to be completely unfolded, and the annular cutter cannot be cut off due to overlarge pressure.
The above applications are only some of the embodiments of the present application. It will be apparent to those skilled in the art that various modifications and improvements can be made without departing from the spirit of the inventive concept.
Claims (5)
1. A corneal stroma lens ring maker, which is characterized by comprising a base, a casing and a ring cutter;
the base is used for containing lenses and comprises a circular fixing base positioned at the lowest part, a cylindrical bearing part is arranged in the center of the circular fixing base, a groove with the diameter of 6.5mm is arranged in the center of the top end of the bearing part, and the groove is used for containing and fixing the lenses;
the shell is used for connecting the base and the ring cutter and comprises a guide part positioned above and a positioning part positioned below the guide part, the guide part and the positioning part are hollow cylinders, the outer diameters of the guide part and the positioning part are the same, the inner diameters are different, the inner diameter of the positioning part is not smaller than the outer diameter of the bearing part, the inner diameter of the guide part is not smaller than the outer diameter of the cutter handle,
the annular cutter comprises a cutter blade and a cutter handle, the cutter blade is annular and is arranged below the cutter handle, the cutter handle comprises a cylindrical cutter handle body and a holding part of the cutter handle body, the positioning part of the casing ensures that the casing is positioned and fixed with the base, and the guiding part ensures that the annular cutter vertically cuts the cornea stroma lens downwards;
the diameter of the base is 22.5mm, the diameter of the cylindrical bearing part is 10.5mm, the height of the cylindrical bearing part is 10mm, and the depth of a groove in the center of the top end of the bearing part is 0.5mm; the inner diameter of the positioning part is 10.6mm;
the diameter of the cutter blade is 1mm and 3mm, the caliber of 1mm is used for manufacturing a 1mm lens, the caliber of 3mm is used for manufacturing a 3mm lens and an annular lens with the inner diameter of 3mm, and the cutter handle body is cylindrical and has the diameter of 6.45mm;
the internal diameter of the guide part is gradually reduced from top to bottom, grease is arranged between the sleeve shell and the cutter handle body to realize an oil seal, an exhaust channel is formed between the positioning part of the sleeve shell and the bearing part of the base, and a circle of porous material is arranged in an annular gap between the positioning part and the circular fixing base.
2. A corneal stromal lens ring maker as defined in claim 1, wherein the handle body is positioned in the guide portion of the sleeve and the grip is positioned above the guide portion of the sleeve when making the corneal stromal lens.
3. The device of claim 1, wherein the inner wall of the positioning portion is attached to the outer wall of the carrier portion when the stromal corneal lens is produced.
4. A corneal stroma lens ring maker according to claim 1, wherein the blade is 3mm high.
5. The corneal stroma lens ring maker as in claim 1, wherein the blade material is an artificial gemstone, the handle body is stainless steel, and the grip surface is frosted.
Priority Applications (1)
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CN202311015742.7A CN117122468B (en) | 2023-08-14 | 2023-08-14 | Cornea stroma lens ring producer |
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CN202311015742.7A CN117122468B (en) | 2023-08-14 | 2023-08-14 | Cornea stroma lens ring producer |
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CN117122468A CN117122468A (en) | 2023-11-28 |
CN117122468B true CN117122468B (en) | 2024-04-09 |
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CN113730092A (en) * | 2021-08-30 | 2021-12-03 | 四川大学华西医院 | Cornea trephine |
CN114224603A (en) * | 2022-01-12 | 2022-03-25 | 北京大学人民医院 | Negative pressure marked cornea trephine and operation method thereof |
CN114869589A (en) * | 2022-05-24 | 2022-08-09 | 北京大学人民医院 | Fixed depth cornea mark trephine |
CN218279950U (en) * | 2022-05-24 | 2023-01-13 | 北京大学人民医院 | Fixed depth cornea mark trephine |
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