CN117057594A - Laboratory sample cultivation data monitoring system - Google Patents

Laboratory sample cultivation data monitoring system Download PDF

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CN117057594A
CN117057594A CN202311322955.4A CN202311322955A CN117057594A CN 117057594 A CN117057594 A CN 117057594A CN 202311322955 A CN202311322955 A CN 202311322955A CN 117057594 A CN117057594 A CN 117057594A
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郎旭梅
孙淼
丁岳嵩
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Qingdao Dashoo Huachuang Technology Co ltd
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Abstract

The application discloses a laboratory sample cultivation data monitoring system and a method, wherein the system specifically comprises the following steps: the system comprises a culture task management module, a culture data input module, a reminding module and a data monitoring module. The culture task management module sends a first reminding signal to the reminding module every interval preset time according to bacterial strain information of each culture task, the reminding module reminds a worker to input culture data corresponding to the culture task after receiving the first reminding signal, the data monitoring module checks the culture data and culture parameters corresponding to the culture task, if the detection is not passed, a second reminding signal is sent to the reminding module, and the reminding module reminds the worker to verify after receiving the second reminding signal. The laboratory sample cultivation data monitoring system can monitor the bacterial cultivation data in a full period and improve the comprehensiveness of the examination.

Description

Laboratory sample cultivation data monitoring system
Technical Field
The application relates to the field of sample cultivation, in particular to a laboratory sample cultivation data monitoring system.
Background
The bacterial culture is one of important experimental techniques in microbiology, can be used for researching the growth, metabolism, physiological characteristics, genetic variation and the like of bacteria, and provides strain materials for further experimental research of the bacteria in the next step, and the bacterial culture is the basis of bacterial culture, so that the quality of the whole period management of culture data in the culture process directly influences whether the subsequent experimental research is reliable. However, at present, staff often fill in the culture data manually, the timeliness and accuracy of filling in the data cannot be guaranteed, and a system for monitoring the whole period of the data specially aiming at bacterial culture is lacking. Meanwhile, in the prior art, in the checking of the input data, the format of the input data is often simply judged, or the input data is simply compared with a preset threshold value, and the checking mode has certain unilateral performance. In the conventional inspection means in the prior art, the superparameter is also required to be set manually, or the results of different superparameters are required to be compared in a complicated way to set better superparameters, so subjectivity exists.
Disclosure of Invention
The application aims to provide a laboratory sample cultivation data monitoring system, a laboratory sample cultivation data checking method and a storage medium, so as to better solve the problems in the prior art.
In order to achieve the above purpose, the present application provides the following technical solutions:
a laboratory sample incubation data monitoring system, comprising:
the system comprises a culture task management module, a culture data input module, a reminding module and a data monitoring module;
when a culture task is newly added, a culture task management module acquires culture parameters of the culture task, wherein the culture parameters comprise bacterial strains, initial quantity, culture temperature and content of each component of a culture medium;
the culture task management module sends a first reminding signal to the reminding module at intervals of preset time according to bacterial strain information of each culture task, and the reminding module reminds a worker to input culture data of the corresponding culture task after receiving the first reminding signal;
the culture data input module is used for receiving culture data input by a worker, and the input culture data comprises the current bacterial number;
the data monitoring module is used for checking the culture data and the culture parameters of the corresponding culture tasks, if the culture data and the culture parameters of the corresponding culture tasks do not pass the check, a second reminding signal is sent to the reminding module, and the reminding module reminds workers to verify after receiving the second reminding signal;
the data monitoring module checks the culture data and the culture parameters of the corresponding culture tasks by the following steps:
step S1, acquiring culture task information of the same bacterial strain as the checked culture task to form a task set T; wherein,,/>represents the ith cultivation task information in the task set T, n is the total number of the obtained cultivation task information, wherein +.>,/>The incubation temperature for the ith incubation task, < > and->1,2, … for the ith cultivation task, the content of x medium components, x being the total number of medium component types, +.>Bacterial count of the incubation data entered for the 1,2, …, y times for the i-th incubation task, y being the total number of entered incubation data for the checked incubation task;
step S2, for the information of the culturing taskIn the case of examination, first->Information about other incubation tasks>Normalized Euclidean distance between->Sequencing from small to large, and recording the m-th sequenced culture task information asWherein m is->The nearest odd integer; definitions->WhereinThe method comprises the steps of carrying out a first treatment on the surface of the Definitions->
Step S3, ifAnd->The data monitoring module judges the cultivation task information +.>Checking not to pass, wherein alpha and beta are threshold adjustment parameters;
and S4, repeating the steps S2 and S3 for checking all the cultivation task information.
Further, for the same bacterial strain, the culture task management module sends a first reminding signal to the reminding module at the same preset time intervals; the entered incubation data does not include time information.
Further, the data monitoring module judges the information of the culturing taskAfter the test fails, the data monitoring module also performs the following steps:
step U1, judging the information of the culturing taskParameter->Whether there is a problem;
step U2, if the problem is not checked in the step U1, judging task informationParameters of (a)Whether there is a problem.
Further, step U1 includes:
step U1.1, obtaining and culturing task informationA growth model of the same species, the growth model comprising a function curve y=f (t) of the change in bacterial quantity y as a function of time t;
step U1.2, constructing a discrete point setWhere dt is the time interval of the entered culture data, using the discrete point set +.>For curve->Fitting to obtain the optimal fitting parameters +.>Best fit curve +.>
Step U1.3For use inCalculating the distance of each discrete point from the best fit curve representing the bacterial count of the culture data entered at the j-th time>And standard deviation->The method comprises the steps of carrying out a first treatment on the surface of the Definitions->Wherein->If->If the number is greater than 2, judging the +.>Errors may exist and the alert module alerts the staff to verify the data.
Further, step U2 includes:
step U2.1, all of step S1All ignore->Parameters and after parameter neglect steps S2-S4 are performed, if the check is not passed, judging +.>Parameter checking is not passed;
step U2.2, sequentially combining all of the steps S1All ignore->Parameters (parameters)And executing the steps S2-S4 after the parameter is ignored, and if the parameter is not passed, judging that the corresponding ignored parameter is not passed;
and step U2.3, if only one parameter check in the steps U2.1 and U2.2 is failed, reminding a worker to verify the parameter, and if a plurality of parameter checks are failed, reminding the worker to verify the culture parameters of the corresponding culture tasks.
And a laboratory sample incubation data inspection method, comprising:
the laboratory sample cultivation data comprise cultivation parameters of cultivation tasks and cultivation data corresponding to the cultivation tasks are recorded by staff at preset intervals, wherein the cultivation parameters comprise bacterial strains, initial quantity, cultivation temperature and content of each component of a culture medium; the entered culture data includes the current bacterial count;
checking the culture data and the culture parameters of the corresponding culture tasks by the following steps:
step S1, acquiring culture task information of the same bacterial strain as the checked culture task to form a task set T; wherein,,/>represents the ith cultivation task information in the task set T, n is the total number of the obtained cultivation task information, wherein +.>,/>The incubation temperature for the ith incubation task, < > and->1,2, … for the ith cultivation task, the content of x medium components, x being the total number of medium component types, +.>Bacterial count of the incubation data entered for the 1,2, …, y times for the i-th incubation task, y being the total number of entered incubation data for the checked incubation task;
step S2, for the information of the culturing taskIn the case of examination, first->Information about other incubation tasks>Normalized Euclidean distance between->Sequencing from small to large, and recording the m-th sequenced culture task information asWherein m is->The nearest odd integer; definitions->Wherein->The method comprises the steps of carrying out a first treatment on the surface of the Definitions->
Step S3, ifAnd->Judging the cultivation task information->Checking not to pass, wherein alpha and beta are threshold adjustment parameters;
and S4, repeating the steps S2 and S3 for checking all the cultivation task information.
Further, when judging the cultivation task informationAfter the examination fails, the task information is checked further by the following steps +.>
Step U1.1, obtaining and culturing task informationA growth model of the same species, the growth model comprising a function curve y=f (t) of the change in bacterial quantity y as a function of time t;
step U1.2, constructing a discrete point setWhere dt is the time interval of the entered culture data, using the discrete point set +.>For curve->Fitting to obtain the optimal fitting parameters +.>Best fit curve +.>
Step U1.3, useCalculating the distance of each discrete point from the best fit curve representing the bacterial count of the culture data entered at the j-th time>And standard deviation->The method comprises the steps of carrying out a first treatment on the surface of the Definitions->Wherein->If->If the number is greater than 2, judging the +.>Errors may exist;
if no problem is detected in steps U1.1-U1.3, the task information is further checked by the following steps
Step U2.1, all of step S1All ignore->Parameters and after parameter neglect steps S2-S4 are performed, if the check is not passed, judging +.>Parameter checking is not passed;
step U2.2, sequentially combining all of the steps S1All ignore->The parameters are ignored, and after the parameters are ignored, the steps S2-S4 are executed, if the parameters do not pass the inspection, the corresponding ignored parameters are judged to not pass the inspection;
in the step U2.3, if only one parameter check in the steps U2.1 and U2.2 is failed, the parameter is judged to be verified, but if a plurality of parameter checks are failed, the culture parameters of the corresponding culture tasks are judged to be verified.
And a computer readable storage medium having instructions stored therein that when executed on a computer cause the computer to perform the laboratory sample incubation data inspection method described above.
Compared with the prior art, the application has the innovative points and beneficial effects that:
1. through setting up cultivateing task management module, cultivate data entry module, remind the module, through timely reminding the staff to input the cultivate data that corresponds the cultivate task, can effectively manage laboratory sample cultivate data.
2. The data monitoring module is arranged to check the culture data and the culture parameters corresponding to the culture tasks, the checking method avoids the influence of subjective factors, the calculation resources can be saved, the checking process utilizes the self rule of bacterial growth, and the checking comprehensiveness is improved.
3. According to the characteristics and rules of the task information in different parameters, the two parameters are distinguished and are independently judged in different modes, so that the inspection comprehensiveness is further improved.
Drawings
FIG. 1 is a schematic diagram of a laboratory sample incubation data monitoring system.
Detailed Description
The application is described in detail below with reference to the attached drawing figures:
the application provides a laboratory sample cultivation data monitoring system which comprises a cultivation task management module, a cultivation data input module, a reminding module and a data monitoring module.
When a culture task is newly added, a culture task management module acquires culture parameters of the culture task, wherein the culture parameters comprise bacterial strains, initial quantity, culture temperature, content of each component of a culture medium and the like. In an alternative embodiment, the culture parameters may be input into the culture task management module by a worker, or some parameter templates may be predefined by the system, so that the worker may directly select when a new culture task is added, or read the culture parameters by scanning a two-dimensional code, etc. The above-mentioned culture parameters are exemplary parameters, and parameters can be deleted or added according to actual requirements, such as illumination intensity, humidity, etc.
The culture task management module sends a first reminding signal to the reminding module at intervals of preset time according to bacterial strain information of each culture task, and the reminding module reminds workers to input culture data of corresponding culture tasks after receiving the first reminding signal. For managing and monitoring laboratory sample culture data in a full period, the culture data are required to be recorded in a timing manner for each culture task so as to track, analyze and keep a file for the culture condition, and the culture task management module manages and monitors the time of recording the culture data of all the culture tasks, namely, for each culture task, the culture task management module reminds a worker to record the culture data of the corresponding culture task at intervals. For different bacterial strains, the required time interval for inputting the culture data can be different, for example, for a strain which is slow to reproduce, a longer time interval for inputting the culture data can be set, but for the same bacterial strain, the time interval for inputting the culture data is preferably the same, namely, for the same bacterial strain, the culture task management module sends a first reminding signal to the reminding module every preset time with the same interval. The interval time corresponding to the bacterial species may be preset in the system in advance to form a preset time.
The culture data input module is used for receiving culture data input by staff, and the input culture data comprises the current bacterial number. The entered incubation data corresponds to its incubation task, i.e. one incubation task over time, multiple incubation data are entered. In alternative embodiments, the entered incubation data may also include further parameters, such as current time, current temperature, etc., depending on the actual management requirements. However, in the general culture process, the temperature is generally kept unchanged, so that the recorded culture data can omit temperature information. For the time information, the time intervals of the same bacterial strain input culture data are preferably the same, so that the time intervals of the culture data input each time can be considered to be the same under the condition that the staff can input the culture data in time and ignore the time difference of each input of the staff, and the input culture data can omit the time information, thereby reducing the input workload of the staff.
The data monitoring module is used for checking the culture data and the culture parameters corresponding to the culture tasks, and if the culture data and the culture parameters do not pass the checking, a second reminding signal is sent to the reminding module, and the reminding module reminds workers to verify after receiving the second reminding signal. It may be provided that the inspection is performed each time the incubation data entry module receives entered incubation data, but more preferably the inspection is performed in unison after a batch of incubation data is entered, the timing and intervals of the inspection being flexibly adjustable according to the computational resources.
In the prior art, in the checking of the input data, the format of the input data is often simply judged or simply compared with a preset threshold value, and the checking mode has certain unilateralness, and cannot check that the correct numerical value of the format is also in the threshold value range, but obviously does not accord with the problem data of the bacterial growth model. The applicant has noted that, for the same bacterial species, the variation of the bacterial number approximately follows the same law, and the recorded data can be checked by using the law, so that in order to solve the above-mentioned problems in the prior art, the applicant also proposes a method for checking the culture data and the culture parameters corresponding to the culture task, so as to improve the comprehensiveness of the checking, and the specific steps are as follows:
step S1, acquiring culture task information of the same bacterial strain as the checked culture task to form a task set T; wherein,,/>represents the ith cultivation task information in the task set T, n is the total number of the obtained cultivation task information, wherein +.>,/>The incubation temperature for the ith incubation task, < > and->1,2, … for the ith cultivation task, the content of x medium components, x being the total number of medium component types, +.>Bacterial count of the incubation data entered for the 1,2, …, y times for the i-th incubation task, y being the total number of times the incubation data was entered for the checked incubation task. Notably, the above +.>The parameter number of (2) is an exemplary number, and the parameters are specifically required to be adjusted correspondingly according to different culture parameters of the culture task and different recorded culture data contents. Meanwhile, if the initial number of the same bacterial species is the same, +.>The initial quantity information may be omitted, otherwise it is necessary to be +.>The dimension of the initial number is newly added. From the definition, the task set T not only comprises the culture task information of the current culture task, but also comprises the culture task information of the culture task of the same bacterial strain, wherein the culture task information comprises culture parameters when the culture task is newly added, and also comprises culture data recorded at preset time intervals.
Step S2, for the information of the culturing taskIn the case of examination, first->Information about other incubation tasks>Normalized Euclidean distance between->Sequencing from small to large, and recording the m-th sequenced culture task information asWherein m is->The nearest odd integer; definitions->Wherein;ρ i The smaller the indication->The less the culture task information with similar parameters, the greater the probability of data error. More preferably, it is also possible to define +.>,σ i The larger the indication is->The larger the standardized Euclidean distance between the data and other training task information is, the larger the probability of data error is.
Step S3, ifThe data monitoring module judges the cultivation task information +.>The inspection is not passed, wherein alpha is a threshold adjustment parameter, can be flexibly adjusted according to the inspection sensitivity requirement, and can be set to 0. More preferably, also can be->The time data monitoring module judges +.>The inspection is not passed, wherein beta is a threshold adjustment parameter, and the parameter can be flexibly adjusted according to the inspection sensitivity requirement and can be set to 0. One of the above two judging conditions can be selected, or the data monitoring module judges +_ when the two judging conditions are satisfied simultaneously>The check does not pass.
And S4, repeating the steps S2 and S3 for checking all the cultivation task information.
The method for checking the culture data and the culture parameters corresponding to the culture tasks can avoid the condition that the super parameters are required to be set manually in the conventional checking means in the prior art, or the results of different super parameters are required to be compared in a complicated way to set better super parameters, thereby avoiding the influence of subjective factors and saving calculation resources (alpha and beta in the method can be completely omitted, so that the parameters are not required to be set manually). Meanwhile, compared with the conventional checking mode, the checking method can only check the current input data, not only check the input data of the current culturing task, but also check the culturing parameters of the current culturing task and the culturing task information of other culturing tasks according to the input data of the culturing task, thereby avoiding the checking limitation in the prior art and further improving the checking comprehensiveness. It can be understood that the more the previous culturing tasks are, the better the effect of the checking method is, and conversely, the applicability of the checking method can be improved by flexibly adjusting alpha and beta for the combination of culturing parameters of the same culturing task.
In a preferred embodiment, the data monitoring module determines the incubation task informationAfter the examination fails, the cultivation task information can be further judged by the following steps>Which part of (a)Parameters may have problems:
step U1, judging the information of the culturing taskParameter->Whether there is a problem;
step U2, if the problem is not checked in the step U1, judging task informationParameters of (a)Whether there is a problem.
Through the steps, due to the task informationParameter->And parametersThe method has the characteristics and the rules, the two parameters are distinguished and are independently judged in different modes, the limitation of inspection in the prior art can be avoided, and the inspection comprehensiveness is further improved.
Wherein, step U1 includes:
step U1.1, obtaining and culturing task informationA growth model of the same species, the growth model comprising a function curve y=f (t) of the change in bacterial quantity y as a function of time t; in the prior art, detailed researches on a bacterial growth model are carried out, and the growth model which is more suitable for practical cultivation can be selected and stored in the system in advance.
Step U1.2, constructing a discrete point setWhere dt is the time interval of the entered culture data, using the discrete point set +.>For curve->Fitting to obtain the optimal fitting parameters +.>Best fit curve +.>. In the prior art, there are various curve fitting methods, for example, a genetic optimization algorithm and other modes can be used to obtain the best fitting parameters so as to obtain the best fitting curve, and the fitting curve under ideal conditions can also be directly obtained through a modeling mode.
Step U1.3, useCalculating the distance of each discrete point from the best fit curve representing the bacterial count of the culture data entered at the j-th time>And standard deviation->The method comprises the steps of carrying out a first treatment on the surface of the Definitions->Wherein->If->If the value is larger than the set threshold, the optimal value is 2 or 3, or the set threshold can be determined according to the requirement, the j-th recorded culture data is judged to be +.>Errors may exist and the alert module alerts the staff to verify the data.
Step U2 includes:
step U2.1, all of step S1All ignore->Parameters and after parameter neglect steps S2-S4 are performed, if the check is not passed, judging +.>Parameter checking is not passed;
step U2.2, sequentially combining all of the steps S1Are all neglected =And after the parameters are ignored, executing the steps S2-S4, and if the inspection does not pass, judging that the inspection corresponding to the ignored parameters does not pass. I.e. first atOnly neglect inParameters, performing S2-S4 for checking; then atOnly neglect inParameters, performing S2-S4 for checking; and so on until allThe parameters are checked in this way.
Step U2.3, if only one parameter in total in steps U2.1 and U2.2 is not checked, reminding the module to remind the staff to verify the parameterIf a plurality of parameter checks are not passed, the reminding module reminds the staff that the culture parameters of the corresponding culture tasks need to be verified. The purpose of this is that if there is a problem with only one parameter, it affects the whole data independently, but if there is a problem with multiple parameters, it is easy to produce a linkage effect, so it is necessary to do so for allThe parameters are verified.
The application also provides a laboratory sample incubation data checking method, which is used for executing the step of checking the data in the laboratory sample incubation data monitoring system, and preferably, the method also comprises the step of reminding the staff in the laboratory sample incubation data monitoring system.
The present application also provides a computer-readable storage medium having instructions stored therein, which when run on a computer, cause the computer to perform the methods of steps S1-S4, steps U1-U2 as described above, by performing these methods, it is possible to perform full cycle monitoring of data of bacterial cultures and to improve the integrity of the examination.
It should be understood that, in the embodiments of the present application, the preferred embodiments may be arbitrarily combined, and the sequence number of the steps does not mean that the steps are performed sequentially, and meanwhile, the steps may be arbitrarily combined, and the order and combination of the steps should be determined by the functions and the inherent logic thereof, and should not limit the implementation process of the embodiments of the present application.

Claims (8)

1. A laboratory sample incubation data monitoring system, comprising:
the system comprises a culture task management module, a culture data input module, a reminding module and a data monitoring module;
when a culture task is newly added, a culture task management module acquires culture parameters of the culture task, wherein the culture parameters comprise bacterial strains, initial quantity, culture temperature and content of each component of a culture medium;
the culture task management module sends a first reminding signal to the reminding module at intervals of preset time according to bacterial strain information of each culture task, and the reminding module reminds a worker to input culture data of the corresponding culture task after receiving the first reminding signal;
the culture data input module is used for receiving culture data input by a worker, and the input culture data comprises the current bacterial number;
the data monitoring module is used for checking the culture data and the culture parameters of the corresponding culture tasks, if the culture data and the culture parameters of the corresponding culture tasks do not pass the check, a second reminding signal is sent to the reminding module, and the reminding module reminds workers to verify after receiving the second reminding signal;
the data monitoring module checks the culture data and the culture parameters of the corresponding culture tasks by the following steps:
step S1, acquiring culture task information of the same bacterial strain as the checked culture task to form a task set T; wherein,,/>represents the ith cultivation task information in the task set T, n is the total number of the obtained cultivation task information, wherein +.>,/>The incubation temperature for the ith incubation task, < > and->1,2, … for the ith cultivation task, the content of x medium components, x being the total number of medium component types, +.>1 st of the ith cultivation task2, …, the bacterial count of the culture data entered y times, y being the total number of entered culture data of the checked culture task;
step S2, for the information of the culturing taskIn the case of examination, first->Information about other incubation tasks>Normalized Euclidean distance between->Sequencing from small to large, and marking the m-th culture task information after sequencing as +.>Wherein m is->The nearest odd integer; definitions->WhereinThe method comprises the steps of carrying out a first treatment on the surface of the Definitions->
Step S3, ifAnd->The data monitoring module judges the cultivation task information +.>Checking not to pass, wherein alpha and beta are threshold adjustment parameters;
and S4, repeating the steps S2 and S3 for checking all the cultivation task information.
2. The laboratory sample incubation data monitoring system of claim 1, wherein,
for the same bacterial strain, the culture task management module sends a first reminding signal to the reminding module at the same preset time intervals; the entered incubation data does not include time information.
3. The laboratory sample incubation data monitoring system of claim 1, wherein,
the data monitoring module judges the information of the culturing taskAfter the test fails, the data monitoring module also performs the following steps:
step U1, judging the information of the culturing taskParameter->Whether there is a problem;
step U2, if the problem is not checked in the step U1, judging task informationParameter->Whether there is a problem.
4. The laboratory sample incubation data monitoring system of claim 3, wherein,
the step U1 comprises the following steps:
step U1.1, obtaining and culturing task informationA growth model of the same species, the growth model comprising a function curve y=f (t) of the change in bacterial quantity y as a function of time t;
step U1.2, constructing a discrete point setWhere dt is the time interval of the entered culture data, using the discrete point set +.>For curve->Fitting to obtain the optimal fitting parameters +.>Best fit curve +.>
Step U1.3, useCalculating the distance of each discrete point from the best fit curve representing the bacterial count of the culture data entered at the j-th time>And standard deviation->The method comprises the steps of carrying out a first treatment on the surface of the Definitions->WhereinIf->If the number is greater than 2, judging the +.>Errors may exist and the alert module alerts the staff to verify the data.
5. The laboratory sample incubation data monitoring system of claim 3, wherein,
step U2 includes:
step U2.1, all of step S1All ignore->Parameters and after parameter neglect steps S2-S4 are performed, if the check is not passed, judging +.>Parameter checking is not passed;
step U2.2, sequentially combining all of the steps S1All ignore->The parameters are ignored, and after the parameters are ignored, the steps S2-S4 are executed, if the parameters do not pass the inspection, the corresponding ignored parameters are judged to not pass the inspection;
and step U2.3, if only one parameter check in the steps U2.1 and U2.2 is failed, reminding a worker to verify the parameter, and if a plurality of parameter checks are failed, reminding the worker to verify the culture parameters of the corresponding culture tasks.
6. A laboratory sample incubation data inspection method, comprising:
the laboratory sample cultivation data comprise cultivation parameters of cultivation tasks and cultivation data corresponding to the cultivation tasks are recorded by staff at preset intervals, wherein the cultivation parameters comprise bacterial strains, initial quantity, cultivation temperature and content of each component of a culture medium; the entered culture data includes the current bacterial count;
checking the culture data and the culture parameters of the corresponding culture tasks by the following steps:
step S1, acquiring culture task information of the same bacterial strain as the checked culture task to form a task set T; wherein,,/>represents the ith cultivation task information in the task set T, n is the total number of the obtained cultivation task information, wherein +.>,/>The incubation temperature for the ith incubation task, < > and->1,2, … for the ith cultivation task, the content of x medium components, x being the total number of medium component types, +.>Bacterial count of the incubation data entered for the 1,2, …, y times for the i-th incubation task, y being the total number of entered incubation data for the checked incubation task;
step S2, for the information of the culturing taskIn the case of examination, first->Information about other incubation tasks>Normalized Euclidean distance between->Sequencing from small to large, and marking the m-th culture task information after sequencing as +.>Wherein m is->The nearest odd integer; definitions->WhereinThe method comprises the steps of carrying out a first treatment on the surface of the Definitions->
Step S3, ifAnd->Judging the cultivation task information->Checking not to pass, wherein alpha and beta are threshold adjustment parameters;
and S4, repeating the steps S2 and S3 for checking all the cultivation task information.
7. The laboratory sample incubation data examination method of claim 6, wherein,
when judging the information of the culturing taskAfter the examination fails, the task information is checked further by the following steps +.>
Step U1.1, obtaining and culturing task informationA growth model of the same species, the growth model comprising a function curve y=f (t) of the change in bacterial quantity y as a function of time t;
step U1.2, constructing a discrete point setWhere dt is the time interval of the entered culture data, using the discrete point set +.>For curve->Fitting to obtain the optimal fitting parameters +.>Best fit curve +.>
Step U1.3, useCalculating the distance of each discrete point from the best fit curve representing the bacterial count of the culture data entered at the j-th time>And standard deviation->The method comprises the steps of carrying out a first treatment on the surface of the Definitions->WhereinIf->If the number is greater than 2, judging the +.>Errors may exist;
if no problem is detected in steps U1.1-U1.3, the task information is further checked by the following steps
Step U2.1, all of step S1All ignore->Parameters and after parameter neglect steps S2-S4 are performed, if the check is not passed, judging +.>Parameter checking is not passed;
step U2.2, sequentially combining all of the steps S1All ignore->The parameters are ignored, and after the parameters are ignored, the steps S2-S4 are executed, if the parameters do not pass the inspection, the corresponding ignored parameters are judged to not pass the inspection;
in the step U2.3, if only one parameter check in the steps U2.1 and U2.2 is failed, the parameter is judged to be verified, but if a plurality of parameter checks are failed, the culture parameters of the corresponding culture tasks are judged to be verified.
8. A computer readable storage medium having instructions stored therein which, when run on a computer, cause the computer to perform the method of any of claims 6-7.
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