CN116966401A - Human body intracavity drug administration plugging balloon catheter - Google Patents
Human body intracavity drug administration plugging balloon catheter Download PDFInfo
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- CN116966401A CN116966401A CN202311125955.5A CN202311125955A CN116966401A CN 116966401 A CN116966401 A CN 116966401A CN 202311125955 A CN202311125955 A CN 202311125955A CN 116966401 A CN116966401 A CN 116966401A
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- medicine
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- 238000001647 drug administration Methods 0.000 title claims abstract description 18
- 239000003814 drug Substances 0.000 claims abstract description 93
- 229940079593 drug Drugs 0.000 claims abstract description 19
- 238000012377 drug delivery Methods 0.000 claims description 22
- 230000004087 circulation Effects 0.000 claims description 12
- 238000002347 injection Methods 0.000 claims description 10
- 239000007924 injection Substances 0.000 claims description 10
- 239000007788 liquid Substances 0.000 abstract description 24
- 210000004369 blood Anatomy 0.000 abstract description 10
- 239000008280 blood Substances 0.000 abstract description 10
- 230000017531 blood circulation Effects 0.000 abstract description 7
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 7
- 230000006378 damage Effects 0.000 abstract description 6
- 210000005077 saccule Anatomy 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 5
- 230000029058 respiratory gaseous exchange Effects 0.000 abstract description 4
- 230000002035 prolonged effect Effects 0.000 abstract description 3
- 210000004204 blood vessel Anatomy 0.000 description 8
- 210000003437 trachea Anatomy 0.000 description 4
- 230000006837 decompression Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 229930012538 Paclitaxel Natural products 0.000 description 2
- 206010057469 Vascular stenosis Diseases 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 229960001592 paclitaxel Drugs 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 229910000566 Platinum-iridium alloy Inorganic materials 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 238000005253 cladding Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- HWLDNSXPUQTBOD-UHFFFAOYSA-N platinum-iridium alloy Chemical class [Ir].[Pt] HWLDNSXPUQTBOD-UHFFFAOYSA-N 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000009991 scouring Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- A61M25/10—Balloon catheters
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- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
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- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
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- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
- A61B2017/22045—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire fixed to the catheter; guiding tip
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- A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
- A61B2017/22054—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation with two balloons
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- A61B2017/22051—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
- A61B2017/22065—Functions of balloons
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- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M2025/0037—Multi-lumen catheters with stationary elements characterized by lumina being arranged side-by-side
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
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- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
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- A—HUMAN NECESSITIES
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- A61M25/00—Catheters; Hollow probes
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- A61M2025/1043—Balloon catheters with special features or adapted for special applications
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- A61M2025/1072—Balloon catheters with special features or adapted for special applications having balloons with two or more compartments
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- A61M2025/1043—Balloon catheters with special features or adapted for special applications
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- A61M2210/00—Anatomical parts of the body
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- A61M2210/00—Anatomical parts of the body
- A61M2210/10—Trunk
- A61M2210/1042—Alimentary tract
Abstract
The application discloses a human body intracavity drug administration plugging sacculus catheter, which comprises the following components: a three-lumen catheter and two balloons arranged on the three-lumen catheter and spaced at a certain distance; the three-cavity catheter is internally provided with a main cavity channel, a drug administration cavity channel and a pressure filling and releasing cavity channel. After the two saccules swell, the two ends of the focus are blocked, so that the medicine can be directly poured into the focus and the medicine liquid can be timely recovered, the medicine dosage dispersed to other parts of the human body through blood, air passages or digestive tracts is reduced, and the damage of excessive medicine to the human body is reduced; a plurality of administration holes which directly face the focus are arranged between the two sacculus, so that the quick in-out of the liquid medicine is realized, and the administration efficiency is improved; the three-cavity catheter has the advantages that the cavity design of the three-cavity catheter ensures that the blockage of the cavity of a human body and the application of medicines are realized on the premise of not affecting the normal respiration and the blood circulation of a patient, so that the administration time can be prolonged, and the discomfort of the patient in the treatment process can be reduced.
Description
Technical Field
The application relates to the technical field of application of medicines in human body cavities, in particular to an intra-cavity medicine administration plugging balloon catheter.
Background
In the process of human body cavity treatment, direct application to a focus is sometimes required, and the currently commonly used application modes of the internal cavity medicament mainly comprise two types, namely a spraying and administration mode and another type, wherein the medicine is directly conveyed to the focus by a conveying pipe and is released.
The treatment of the common airway and the digestive tract adopts a spray mode for administration, but the liquid medicine is difficult to remain at the focus part along with the respiration of the human body and the scouring caused by food flow, and the spray mode for administration generally adopts an excessive administration, so that a large amount of excessive liquid medicine enters the human body to cause harm to the human body.
In order to treat vascular stenosis, the existing administration mode mainly uses a balloon to combine with a stent to convey the medicament to the vascular stenosis part, but a large amount of medicament in the balloon can be washed away by blood in the process of moving the stent to the focus part, so that the medicament is insufficient when reaching the focus part. Therefore, the medicine with larger dosage can be sprayed on the surface of the saccule, so that the total amount of the medicine blended into the human body is greatly increased, the medicine such as paclitaxel and the like is harmful to the human body, and the non-focus part needs to be prevented from contacting the medicine as much as possible.
Disclosure of Invention
In order to solve the technical problems, the application provides an intra-cavity drug administration plugging balloon catheter for a human body. The following presents a simplified summary in order to provide a basic understanding of some aspects of the disclosed embodiments. This summary is not an extensive overview and is intended to neither identify key/critical elements nor delineate the scope of such embodiments. Its sole purpose is to present some concepts in a simplified form as a prelude to the more detailed description that is presented later.
The application adopts the following technical scheme:
the application provides an intra-cavity drug administration plugging balloon catheter of a human body, which comprises the following components: a three-lumen catheter and two balloons arranged on the three-lumen catheter and spaced at a certain distance;
a main cavity channel, a drug administration cavity channel and a pressure filling and releasing cavity channel are arranged in the three-cavity catheter;
the inner end of the main cavity channel is provided with a circulation inlet, and the outer end of the main cavity channel or the pipe body of the three-cavity catheter is provided with a circulation outlet communicated with the main cavity channel;
a plurality of drug delivery holes positioned between the two balloons are formed in the cavity wall of the drug delivery cavity;
the pressure filling and releasing cavity is communicated with the inner cavities of the two balloons.
Further, the utility model provides an intracavitary administration shutoff sacculus pipe of human, still include: the main handle is arranged at the outer end of the three-cavity catheter; and a guide wire passage communicated with the main cavity channel is arranged in the main handle.
Further, the two balloons are coated outside the three-cavity catheter, the two balloons are provided with catheter through holes, and the catheter through holes are positioned at 1/5 of the lower half part of the balloon.
Further, the utility model provides an intracavitary administration shutoff sacculus pipe of human, still include: the developing ring is arranged on the three-cavity catheter and is positioned at the middle part of the two balloons.
Further, the utility model provides an intracavitary administration shutoff sacculus pipe of human, still include: the two-way cock is arranged at the outer end of the main handle.
Further, the utility model provides an intracavitary administration shutoff sacculus pipe of human, still include: the marking ring is arranged on the three-cavity catheter and is positioned at the outer ends of the two balloons.
Further, the utility model provides an intracavitary administration shutoff sacculus pipe of human, still include: a drug delivery handle; the drug delivery handle is internally provided with a drug injection pipeline, one end of the drug injection pipeline is communicated with the drug delivery cavity, and the other end of the drug injection pipeline is provided with a drug delivery port connected with the drug delivery device.
Further, the utility model provides an intracavitary administration shutoff sacculus pipe of human, still include: a pressure charging and releasing handle; the pressure filling and releasing handle is internally provided with a medium pipeline, one end of the medium pipeline is communicated with the pressure filling and releasing cavity, and the other end of the medium pipeline is provided with a medium conveying port connected with the pressure filling and releasing device.
Further, a first guide pipe extends out of the outer end of the administration cavity, and the administration handle is connected with the three-cavity guide pipe through the first guide pipe; the outer end of the pressure filling and releasing cavity channel extends out of a second guide pipe, and the pressure filling and releasing handle is connected with the three-cavity guide pipe through the second guide pipe.
The application has the beneficial effects that:
1. after the two saccules swell, the two ends of the focus are blocked, and a medicine applying cavity aiming at the focus position is formed, so that medicine can be directly poured into the focus, medicine liquid can be timely recovered, the medicine amount dispersed to other parts of a human body through blood, an air passage or a digestive tract is reduced, the medicine liquid utilization efficiency is effectively improved, and the harm of excessive medicine to the human body can be reduced;
2. a plurality of drug administration holes which directly face the focus are arranged between the two sacculus, so that the rapid drug inlet and outlet can be realized on the premise of ensuring the drug application effect, and the drug administration efficiency is improved;
3. the three-cavity catheter has the advantages that the cavity design of the three-cavity catheter ensures that the blockage of the cavity of a human body and the application of medicines are realized on the premise of not affecting the normal respiration and the blood circulation of a patient, so that the administration time can be prolonged, and the discomfort of the patient in the treatment process can be reduced;
4. the structure is succinct, easily operation, and carries out the medicament to focus position and applys, promotes the treatment.
Drawings
In order to more clearly illustrate the embodiments of the application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic illustration of the structure of an administration occlusion balloon catheter when the present application is used intravascularly;
FIG. 2 is a schematic illustration of the structure of an administration occlusion balloon catheter when the present application is used in the airway and digestive tract;
FIG. 3 is a schematic view of the three lumen catheter of the present application;
FIG. 4 is a schematic view of the three lumen catheter of the present application in a blood vessel;
FIG. 5 is a schematic view of the three lumen catheter of the present application in the airway and digestive tract;
fig. 6 is a schematic structural view of the balloon of the present application.
Detailed Description
Embodiments of the present application will be described in detail below with reference to the accompanying drawings. It should be understood that the described embodiments are merely some, but not all, embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
As shown in fig. 1-5, in some illustrative embodiments, the present application provides an intra-luminal delivery occlusion balloon catheter for direct application of a medicament to a focal site during treatment of a human body lumen, comprising: a three-cavity catheter 1, a balloon 2, a main handle 3, a drug delivery handle 4 and a pressure filling and releasing handle 5.
The number of the sacculus 2 is two, and the two sacculus 2 are arranged on the three-cavity catheter 1 at a certain distance, when the two sacculus 2 swell, the human body cavity can be blocked, and the two sacculus 2 and the inner wall of the human body cavity enclose to form a medicament application cavity 6. The medicine applying cavity 6 is established aiming at the focus position, the medicine can directly act on the focus after being injected, the treatment effect is ensured, and the blocking effect of the two saccule 2 can also prevent the medicine from diffusing to other positions along the human body cavity, so that the damage to the human body caused by excessive medicine absorption is avoided.
Three mutually independent channels are arranged in the three-cavity catheter 1, namely a main cavity channel 101, a drug administration cavity channel 102 and a pressure filling and releasing cavity channel 103. At the same time, the triple lumen catheter 1 may be designed to have multiple diameters to meet the therapeutic needs of different diameter lumens.
The wall of the administration channel 102 is provided with a plurality of administration holes 1021 between the two balloons 2, and the medicine is injected from the administration channel 102 and enters the medicine applying cavity 6 through the administration holes 1021 to directly act on the focus or is extracted by applying negative pressure to the administration channel 102, namely, the rest medicine enters the administration channel 102 through the administration holes 1021 and is extracted outside the body. A plurality of administration holes 1021 which directly face the focus are arranged between the two sacculus 2, so that the medicine liquid can be rapidly fed and discharged on the premise of ensuring the medicine application effect, and the administration efficiency is improved.
The inflation and deflation channel 103 is communicated with the inner cavities of the two balloons 2. Specifically, two sacculus 2 have all offered the pipe through hole for three chamber pipe 1 can pass the pipe through hole, and two sacculus 2 cladding are in the outside of three chamber pipe 1. The wall of the pressure-filling and releasing channel 103 is perforated 1031, that is, the hole 1031 is located on the wall of the through hole of the catheter, and the hole 1031 is communicated with the inner cavity of the balloon 2. The medium can be injected through the pressure filling and releasing cavity 103, the medium can be air or normal saline, and the medium is injected from the pressure filling and releasing cavity 103 and enters the inner cavity of the balloon 2 through the hole 1031, so that the balloon 2 bulges. After the administration is completed, the medium is extracted by applying negative pressure to the pressurizing and depressurizing channel 103, so that the balloon 2 is retracted.
The forming mold of the balloon 2 is a special-shaped mold, that is, as shown in fig. 6, the volume of the upper portion of the balloon 2 is larger than the volume of the lower portion, and in this embodiment, the balloon 2 is divided into the upper portion and the lower portion by using the position of the catheter through hole. The catheter penetration hole is located at 1/5 of the lower part of the balloon, i.e. if the height of the balloon 2 after inflation is set to be D, the height of the upper part of the balloon 2 is 4D/5, and the height of the lower part is 1D/5. After the balloon 2 is swelled by the structural design, the three-cavity catheter 1 is positioned at the lower end position of the balloon 2, so that the three-cavity catheter 1 is close to the lower wall of the human body cavity, and the recovery rate of liquid medicine is improved.
The inner end of the main channel 101 is provided with a circulation inlet 1011, the outer end of the main channel 101 is provided with a circulation outlet 1012 communicated with the main channel, or the pipe body of the three-cavity conduit 1 is provided with a circulation outlet 1012 communicated with the main channel 101. In this embodiment, each tube and channel are divided into an outer end and an inner end, wherein the outer end refers to an end close to the field of vision of the doctor, i.e. an end closer to the outside of the human body, and the other end refers to an end far from the outside of the human body as the inner end.
The structural design can ensure that the normal circulation of the human body cavity is maintained after the saccule 2 seals the human body cavity. For example, when using an administration occlusion balloon catheter in a blood vessel, blood flows from the flow-through inlet 1011 into the main lumen 101 and back into the blood vessel through the flow-through outlet 1012 located on the body of the three lumen catheter 1; when the drug administration occlusion balloon catheter is used in the trachea, gas flows into the main channel 101 from the flow inlet 1011 during exhalation and reaches the outside of the body through the flow outlet 1012 at the end of the three-lumen catheter 1, and air enters the main channel 101 from the flow outlet 1012 during inhalation and enters the trachea through the flow inlet 1011. Therefore, even if the trachea is blocked by the balloon 2, air can still circulate, and the administration time is prolonged. After the main channel 101 is plugged by the two-way cock 7 in the blood vessel, the blood circulation function is realized. In addition, since the holes of the perforated balloon in the market are usually formed at two ends of the balloon, the blood flow is small, and the structural design of the embodiment can ensure the normal blood flow.
The main handle 3 is arranged at the outer end of the three-cavity catheter 1. The main handle 3 is internally provided with a guide wire passage 301 communicated with the main handle 101, so that the drug administration plugging balloon catheter of the embodiment can enter a complex lesion position through the guide wire, and after the guide wire is withdrawn, the passage between the main handle 101 and the main handle 3 or the passage inlet 1011 can be realized.
The medicine feeding handle 4 is internally provided with a medicine feeding pipeline 401, one end of the medicine feeding pipeline 401 is communicated with the medicine feeding cavity 102, the other end of the medicine feeding pipeline is provided with a medicine conveying port 402 used for being connected with a medicine feeding device, and the medicine feeding device can be any existing device such as a needle cylinder and the like which can push medicine and extract medicine. The drug delivery handle 4 is connected with an external drug delivery device, and injection and discharge of the drug liquid are realized through the drug injection pipeline 401, so that pushing and drawing of the drug are facilitated.
The medium pipeline 501 is arranged in the pressure filling and releasing handle 5, one end of the medium pipeline 501 is communicated with the pressure filling and releasing cavity 103, the other end of the medium pipeline 501 is provided with a medium conveying port 502 which is used for being connected with a pressure filling and releasing device, and the pressure filling and releasing device can be any existing device for realizing medium pushing and extracting such as a pump. The inflation and decompression handle 5 is connected with an external inflation and decompression device, injection and discharge of media are realized through the media pipeline 501, inflation and decompression of the balloon 2 are further realized, and operation on the balloon is facilitated.
The outer end of the drug administration channel 102 extends out of the first guiding tube 104, and the drug administration handle 4 is connected with the three-cavity catheter 1 through the first guiding tube 104, namely the first guiding tube 104 communicates the drug injection pipeline 401 with the drug administration channel 102; the outer end of the pressure filling and releasing cavity 103 extends out of the second guiding pipe 105, and the pressure filling and releasing handle 5 is connected with the three-cavity catheter 1 through the second guiding pipe 105, namely the second guiding pipe 105 communicates the medium pipeline 501 with the pressure filling and releasing cavity 103. The first guide tube 104 and the second guide tube 105 can extend the length of the handle, so that the external equipment is convenient, and the extraction/pushing operation of the liquid medicine and the medium is convenient.
As shown in fig. 1, when the administration-blocking balloon catheter is used in a blood vessel, the administration-blocking balloon catheter of the present embodiment further includes: the two-way cock 7 and the developing ring 8 arranged on the three-cavity catheter 1, wherein the developing ring 8 is positioned at the middle part of the two balloons 2, and the position at the middle part means that the developing ring 8 is positioned on the bilateral symmetry line of the balloons 2. The developing ring 8 is made of platinum iridium alloy so as to observe the position of the balloon 2 through X-rays, thereby being convenient for accurately positioning the focus position.
The two-way cock 7 is provided at the outer end of the main handle 3. When the administration plugging balloon catheter is used in a blood vessel, the outer end of the main channel 101 is plugged by the two-way cock 7, so that blood is prevented from flowing out of the body, flows into the main channel 101 from the circulation inlet 1011, and flows back into the blood vessel through the circulation outlet 1012 positioned on the body of the three-cavity catheter 1, and the blood circulation function is realized.
As shown in fig. 2, when the administration occlusion balloon catheter is used in the trachea and the alimentary canal, the administration occlusion balloon catheter of the present embodiment further includes: a marker ring 9 is arranged on the three-lumen catheter 1, and the marker ring 9 is positioned at the outer ends of the two balloons 2. For matching with an endoscope, the position of the balloon can be directly observed under the endoscope, so that the marking ring 9 is arranged at the outer end of the balloon 2, namely, near one side of the visual field of a doctor, and the doctor can conveniently position the balloon under the endoscope.
The structural design of the drug administration plugging sacculus catheter realizes that the catheter is firstly delivered and then the drug is injected, so that no drug leaks when the catheter is delivered into the body; when reaching the focus position, the two ends of the focus are blocked by the saccule, and the focus is directly filled with liquid medicine, so that the medicine can be applied in a targeted mode and the medicine can be prevented from diffusing to the periphery; simultaneously, the residual medicine enters the medicine feeding cavity channel 102 through the medicine feeding hole 1021 and is pumped out of the body, so that the medicine liquid is timely recovered. Therefore, the administration of the blocking balloon catheter of the embodiment can reduce the medicament quantity dispersed to other parts of the human body through blood, air passages or digestive tracts, and reduce the injury of excessive medicaments to the human body.
As shown in fig. 4, in the blood vessel, the product reaches the affected part through the guide wire, under the X-ray development, the focus is located between the two balloons 2, the pressure of the balloons 2 is applied by the pressure-filling and releasing handle 5, so that the balloons 2 are inflated until the two balloons 2 seal the two ends of the focus. At this time, the drug solution (paclitaxel or other) is injected through the drug administration handle 4, so that the drug solution is filled and sufficiently contacts the lesion. The main handle 3 is connected with a two-way cock 8, and the two-way cock 8 is rotated to close the main channel 101, so that blood does not flow out of the main channel 101. Since the main channel 101 is closed, blood can enter the main channel 101 through the circulation inlet 1011 and bypass the balloon 2 to flow out of the circulation outlet 1012, thereby greatly prolonging the operation time.
When the liquid medicine fully contacts with the focus, the medicine feeding cavity 102 can be in a negative pressure state, so that part of the liquid medicine flows out of the human body along with blood, meanwhile, the pressure of the liquid medicine is slowly released for the balloon 2, the blood outside the balloon 2 flows to the medicine feeding hole 1021, when the total volume of the recovered liquid is approximately equal to the volume of the injected liquid medicine, the negative pressure is stopped, and meanwhile, the pressure of the balloon 2 is rapidly released. The catheter is then withdrawn. Although part of the liquid medicine is dispersed to the whole body along with blood, the residual quantity is far smaller than that of other methods, such as a medicine balloon, a medicine bracket and the like.
As shown in fig. 5, the catheter is introduced into the human body with the aid of an endoscope in the airway and digestive tract. The balloon positions can be positioned by looking at the marking ring 9 through the endoscope visual field, so that the two balloons 2 are positioned at two ends of the focus, and the pressure-releasing handles 5 are used for inflating the balloons 2, so that the balloons 2 are inflated to seal the airway or the alimentary canal. At this time, the medicine liquid is injected through the medicine feeding handle 4, so that the medicine liquid is full and fully contacts the focus, and at this time, the air in the air passage can enter and exit the plugged air pipe through the main cavity channel 101, so that the breathing of a patient is not influenced.
When the medicine liquid is fully contacted with the focus, negative pressure is applied to the medicine feeding handle 4, so that the medicine liquid flows out of the human body through the medicine feeding hole 1021. Because the balloon 2 adopted by the product is an eccentric balloon, namely, the through hole of the catheter is positioned at 1/5 of the lower half part of the balloon, after the balloon 2 is inflated, the three-cavity catheter 1 is not positioned in the center of the balloon 2, so that the three-cavity catheter 1 is positioned at the lower end of a cavity channel in a human body, and under the action of gravity, the three-cavity catheter 1 can nearly recover all liquid medicine, thereby reducing the harm of the liquid medicine to the human body. Finally, the catheter is withdrawn, and the operation is completed.
The foregoing is merely illustrative of the present application, and the present application is not limited thereto, and any changes or substitutions easily contemplated by those skilled in the art within the scope of the present application should be included in the present application. Therefore, the protection scope of the application is subject to the protection scope of the claims.
Claims (9)
1. An intrabody luminal drug delivery occlusion balloon catheter, comprising: a three-lumen catheter and two balloons arranged on the three-lumen catheter and spaced at a certain distance;
a main cavity channel, a drug administration cavity channel and a pressure filling and releasing cavity channel are arranged in the three-cavity catheter;
the inner end of the main cavity channel is provided with a circulation inlet, and the outer end of the main cavity channel or the pipe body of the three-cavity catheter is provided with a circulation outlet communicated with the main cavity channel;
a plurality of drug delivery holes positioned between the two balloons are formed in the cavity wall of the drug delivery cavity;
the pressure filling and releasing cavity is communicated with the inner cavities of the two balloons.
2. The intrabody cavity administration occlusion balloon catheter of claim 1, further comprising: the main handle is arranged at the outer end of the three-cavity catheter; and a guide wire passage communicated with the main cavity channel is arranged in the main handle.
3. The endovascular drug delivery occlusion balloon catheter of claim 2, wherein the two balloons are wrapped outside the three-lumen catheter, wherein the two balloons are provided with catheter through holes, and wherein the catheter through holes are located at 1/5 of the lower half of the balloon.
4. The intrabody cavity administration occlusion balloon catheter of claim 3, further comprising: the developing ring is arranged on the three-cavity catheter and is positioned at the middle part of the two balloons.
5. The intrabody cavity administration occlusion balloon catheter of claim 4, further comprising: the two-way cock is arranged at the outer end of the main handle.
6. The intrabody cavity administration occlusion balloon catheter of claim 3, further comprising: the marking ring is arranged on the three-cavity catheter and is positioned at the outer ends of the two balloons.
7. An intrabody cavity administration occlusion balloon catheter according to claim 5 or 6, further comprising: a drug delivery handle; the drug delivery handle is internally provided with a drug injection pipeline, one end of the drug injection pipeline is communicated with the drug delivery cavity, and the other end of the drug injection pipeline is provided with a drug delivery port connected with the drug delivery device.
8. The intrabody cavity administration occlusion balloon catheter of claim 7, further comprising: a pressure charging and releasing handle; the pressure filling and releasing handle is internally provided with a medium pipeline, one end of the medium pipeline is communicated with the pressure filling and releasing cavity, and the other end of the medium pipeline is provided with a medium conveying port connected with the pressure filling and releasing device.
9. The endovascular drug delivery occlusion balloon catheter of claim 8, wherein a first guide tube extends from an outer end of the drug delivery lumen, the drug delivery handle being connected to the three lumen catheter by the first guide tube; the outer end of the pressure filling and releasing cavity channel extends out of a second guide pipe, and the pressure filling and releasing handle is connected with the three-cavity guide pipe through the second guide pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311125955.5A CN116966401A (en) | 2023-09-03 | 2023-09-03 | Human body intracavity drug administration plugging balloon catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311125955.5A CN116966401A (en) | 2023-09-03 | 2023-09-03 | Human body intracavity drug administration plugging balloon catheter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116966401A true CN116966401A (en) | 2023-10-31 |
Family
ID=88476809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311125955.5A Pending CN116966401A (en) | 2023-09-03 | 2023-09-03 | Human body intracavity drug administration plugging balloon catheter |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116966401A (en) |
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2023
- 2023-09-03 CN CN202311125955.5A patent/CN116966401A/en active Pending
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