CN116919659A

CN116919659A - Mitral valve repair device

Info

Publication number: CN116919659A
Application number: CN202210364665.5A
Authority: CN
Inventors: 马剑翔; 蔡文彬; 李天竹; 郭克; 赵俊富; 赵金红; 孟磊
Original assignee: Sano Xinchang Medical Technology Co ltd
Current assignee: Sano Xinchang Medical Technology Co ltd
Priority date: 2022-04-07
Filing date: 2022-04-07
Publication date: 2023-10-24

Abstract

The invention relates to the technical field of medical equipment, and aims to provide a mitral valve repair device which is low in invasiveness, does not damage heart functions and hardly affects the heart functions. The mitral valve repair device comprises an implant, an anchor and a connecting wire connecting the implant and the anchor, wherein a locking mechanism for fixing the relative positions of the implant and the connecting wire is arranged in the implant. The invention solves the problems that the existing mitral valve repair device has stronger invasiveness and can affect the heart function.

Description

Mitral valve repair device

Technical Field

The invention relates to the technical field of medical equipment, in particular to a mitral valve repair device.

Background

Mitral regurgitation (Mitral Regurgitation, MR) refers to the inability of the mitral valve to close tightly during systole, such that blood flow from the left atrium does not pass smoothly into the left ventricle or left ventricle during diastole, and blood flows back into the left atrium during systole. The mitral regurgitation patient has an expanded annulus area to compensate for the insufficiency of blood flow due to the insufficient forward blood flow, i.e. the anterior-posterior diameter is increased, but this aggravates the regurgitation situation, and the anterior-posterior diameter of the annulus continues to be increased, thus sinking into the vicious circle which makes the heart function worse.

The traditional method for treating mitral regurgitation is to perform an open sternotomy, which is difficult, traumatic and has extremely high risk. With the development of interventional medical instruments, the mitral valve can be repaired by the current method of interventional mitral valve repair devices, and the repair method has the advantages of small invasiveness, low risk, small wound surface and good postoperative healing, and is beneficial to patients.

The existing mitral valve repair device comprises a room septum anchoring device I, a coronary sinus great vein or a heart wall anchoring device II and a traction wire, wherein the traction wire is arranged between the room septum anchoring device I and the coronary sinus great vein or the heart wall anchoring device II, and a plurality of unidirectional locking anchors for being clamped on the room septum anchoring device I are arranged on the traction wire; one end of the traction wire is also connected with an inner disc, the inner disc is arranged in the atrium of the left atrium, and a locking device for locking the relative position of the traction wire and the inner disc is also arranged between the inner disc and the traction rope. However, the one-way locking anchor and the locking device in the mitral valve repairing device are arranged in the left atrium, so that the invasiveness is strong, the heart function is inevitably damaged, and the one-way locking anchor or the locking device is positioned in the left atrium for a long time, so that the contraction function of the left atrium is adversely affected, and the recovery and the normal life after operation of a patient are not facilitated.

Disclosure of Invention

Therefore, the technical problem to be solved by the invention is to overcome the defects that the mitral valve repairing device in the prior art has strong invasiveness and can influence the heart function, so as to provide the mitral valve repairing device which has low invasiveness, does not damage the heart function and hardly has influence on the heart function.

In order to solve the problems, the invention provides a mitral valve repair device, which comprises an implant, an anchor and a connecting wire for connecting the implant and the anchor, wherein a locking mechanism for fixing the relative positions of the implant and the connecting wire is arranged inside the implant.

Preferably, the locking mechanism comprises at least one stage of sliding groove formed on the inner wall of the implant and an anastomat matched with the sliding groove, the sliding groove is communicated with a connecting line inlet and a connecting line outlet of the implant, the sliding groove is provided with a guiding part and a limiting part, the limiting part is positioned on one side close to the connecting line outlet and is perpendicular to the axis of the sliding groove, and the guiding part is obliquely arranged from the limiting part to the axis; the anastomat is provided with a through hole which is suitable for the connecting wire to pass through, and the aperture of the through hole can be reduced by the extrusion of the anastomat by the guide part.

Preferably, the locking mechanism comprises a plurality of stages of sliding grooves which are arranged in a step shape along the axis, and the arrangement positions of the guiding parts and the limiting parts of the adjacent stages of sliding grooves gradually approach the axis from the direction from the connecting wire outlet to the connecting wire inlet.

Preferably, the stapler comprises a first stapler part and a second stapler part axially symmetrical with respect to the through hole; the inner walls of the first part of the anastomat and the second part of the anastomat are both formed with clamping teeth.

Preferably, the first and second stapler parts are resilient and integrally formed.

Preferably, the stapler also comprises a push tube sleeved on the connecting wire, and one end of the push tube is inserted into the connecting wire outlet and can push the stapler to move along the guide part.

Preferably, the implant is of olive-type or flat-sheet type construction.

Preferably, the anchoring member comprises a rivet fixedly connected to one end of the connecting wire, the rivet having a plurality of outwardly flared anchoring ribs at an end thereof facing the connecting wire.

Preferably, the anchoring ribs have an arc-shaped structure, the free ends of the anchoring ribs are bent in a direction away from the implant, and the anchoring ribs are uniformly distributed along the circumferential direction.

Preferably, the device also comprises a puncture catheter and a catcher, wherein a puncture needle cavity, a guide wire cavity and a liquid cavity are formed in the puncture catheter along the length direction of the puncture catheter, a puncture needle outlet is formed in one side wall of the puncture catheter, a balloon is arranged in the other side wall of the puncture catheter, and the liquid cavity is communicated with the balloon; one end of the fishing device is provided with at least one fishing ring, and the fishing ring is suitable for grabbing the connecting wire.

The invention has the following advantages:

1. the mitral valve repair device comprises an implant, an anchor and a connecting wire for connecting the implant and the anchor, wherein the implant is internally provided with a locking mechanism which can lock the relative position of the connecting wire and the implant, and the locking mechanism is arranged in the implant, so that secondary invasion is not caused to a heart, the invasion to a left atrium is reduced, the working function of the heart is hardly damaged, the influence of an operation on the heart is reduced to the minimum, and the rapid recovery of a patient is facilitated.

2. The mitral valve repairing device provided by the invention, wherein the locking mechanism comprises a chute formed at least one stage on the inner wall of the implant and an anastomat matched with the chute, the side wall of the chute is provided with a guide part and a limit part, the anastomat is provided with a through hole which is suitable for a connecting wire to pass through, the aperture of the through hole of the anastomat can be reduced under the extrusion action of the guide part, the connecting wire is clamped by the anastomat, the purpose of locking the relative position of the connecting wire and the implant is achieved, and the connecting wire is prevented from slipping in the implant.

3. The mitral valve repairing device provided by the invention has the advantages that the locking mechanism comprises the multi-stage sliding grooves which are arranged in a step shape, the arrangement of the guiding parts and the limiting parts of the sliding grooves of the adjacent stages gradually approaches to the axis of the sliding grooves in the direction from the outlet of the connecting wire to the inlet of the connecting wire, namely, the guiding parts and the limiting parts intersect and form an acute angle, so that the anastomat can move in one direction in the sliding grooves to lock the connecting wire, and the connecting wire is prevented from moving randomly in an implanted body.

4. The mitral valve repair device provided by the invention has the advantages that the anastomat consists of the first anastomat component and the second anastomat component which are axially symmetrically arranged relative to the through hole, and the clamping teeth are formed on the inner walls of the first anastomat component and the second anastomat component which are close to the through hole, so that the clamping friction force of the anastomat is improved, and a more fastened clamping and locking connecting line is realized.

5. The mitral valve repair device provided by the invention has the advantages that the implant is of an olive-shaped structure or a flat-sheet-shaped structure, the implant with the shape can be more firmly attached to the coronary sinus, the fixation effect is achieved, the friction and the pressure of the implant on blood vessels can be reduced, and the influence of the implant on heart functions is reduced.

6. The mitral valve repair device provided by the invention has the advantages that the anchoring piece comprises the rivet, the rivet is fixedly connected with one end of the connecting wire, the end, facing the connecting wire, of the rivet is provided with the plurality of outwards-opened anchoring ribs, the anchoring ribs are of arc-shaped structures, the free ends of the anchoring ribs are bent in the direction away from the implant, the anchoring ribs are uniformly distributed along the circumferential direction, the rivet with the structure can be more firmly arranged at the curtain position, the installation stability of the rivet is enhanced, and the influence on the heart function is reduced.

7. The mitral valve repair device provided by the invention further comprises a puncture catheter, wherein a liquid cavity, a guide wire cavity and a puncture needle cavity are formed in the puncture catheter along the length direction of the puncture catheter, a puncture needle outlet is formed in one side wall of the puncture needle cavity, a puncture needle in the puncture catheter can penetrate out of the puncture needle outlet, a balloon is arranged at one end of the liquid cavity, and the balloon is inflated by injecting liquid into the balloon, so that the effect of supporting and fixing the puncture catheter can be achieved.

8. The mitral valve repair device provided by the invention further comprises the catcher, and at least one catcher ring suitable for grabbing the connecting wire is arranged at one end of the catcher, so that the accuracy of the catcher in catching the connecting wire is improved.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present invention, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.

FIG. 1 shows a schematic structural view of a mitral valve repair device of the present invention;

FIG. 2 shows a perspective schematic view of a first embodiment of a mitral valve repair device of the present invention;

FIG. 3 is a schematic view of a mitral valve repair device according to an embodiment of the present invention in an unlocked state;

FIG. 4 is a schematic view showing a locked state of a locking mechanism in a first embodiment of the mitral valve repair device of the present invention;

FIG. 5 shows a schematic structural view of a rivet in a first embodiment of a mitral valve repair device of the present invention;

FIG. 6 shows a cross-sectional view of a puncture catheter in a first embodiment of a mitral valve repair device of the present invention;

FIG. 7 shows a schematic view of a guidewire passing through a puncture catheter in a first embodiment of a mitral valve repair device of the present invention;

FIG. 8 is a schematic view of a balloon inflated state in a first embodiment of a mitral valve repair device of the present invention;

FIG. 9 is a schematic view of a needle penetrating a puncture catheter in a first embodiment of the mitral valve repair device of the present invention;

FIG. 10 is a schematic view of a mitral valve repair device according to an embodiment of the present invention with a needle penetrating a puncture catheter;

FIG. 11 is a schematic view of a catcher needle exiting a needle in a first embodiment of a mitral valve repair device of the present invention;

FIG. 12 shows a schematic view of a puncture needle bending in a first embodiment of the mitral valve repair device of the present invention;

FIG. 13 shows a schematic view of a needle of a mitral valve repair device according to a first embodiment of the present invention;

FIG. 14 shows a side view of a bendable catheter entering the left atrium during a procedure;

FIG. 15 shows a side view of an implant rivet during surgery;

FIG. 16 shows a side view of a rivet penetration curtain during surgery;

FIG. 17 shows a side view of the rivet deployed through the curtain during surgery;

figure 18 shows a side view of the super-hard guidewire after withdrawal during surgery;

FIG. 19 shows a side view of a withdrawn portion of a bendable catheter during a surgical procedure;

FIG. 20 shows a side view of a puncture catheter entering the coronary sinus during a surgical procedure;

FIG. 21 shows a schematic view of an intra-operative puncture catheter reaching a designated location;

FIG. 22 shows a schematic representation of the inflation of a balloon in the coronary sinus during surgery;

FIG. 23 shows a schematic view of an intraoperative needle penetrating the coronary sinus;

FIG. 24 shows a schematic view of an intraoperative catcher grasping a connecting wire;

FIG. 25 shows a side view of the intraoperative catcher grasping a connecting wire;

FIG. 26 shows a schematic view of the intraoperative suture being pulled into the needle;

FIG. 27 shows a side view of the intraoperative connecting wire pulled out of the heart;

FIG. 28 shows a schematic view of the balloon contracting in the coronary sinus during surgery;

FIG. 29 shows a schematic drawing of the intraoperative connecting wire pulled out of the heart;

FIG. 30 shows a schematic view of an intraoperative implant entering the coronary sinus;

FIG. 31 shows a schematic view of an intra-operative implant reaching a designated location;

FIG. 32 shows a schematic view of the tension of the connecting wire during surgery;

FIG. 33 shows a schematic view of an intraoperative cutter severing a line of attachment;

FIG. 34 shows a schematic view of a surgically completed mitral valve repair device after implantation;

FIG. 35 shows a side view of an intraoperative in-line rivet penetrating curtain;

FIG. 36 shows a side view of an intraoperative ultra-hard guidewire puncture curtain;

FIG. 37 illustrates a side view of an embodiment of another implant rivet in operation;

FIG. 38 shows a side view of another implant rivet through a curtain during surgery;

FIG. 39 shows a perspective schematic view of a second embodiment of a mitral valve repair device of the present invention;

FIG. 40 is a schematic view of a second embodiment of a mitral valve repair device of the present invention in an unlocked state with a locking mechanism;

fig. 41 is a schematic view showing a locked state of a locking mechanism of a second embodiment of the mitral valve repair device of the present invention.

Reference numerals illustrate:

101. an implant; 1011. a connection line inlet; 1012. a connecting wire outlet; 102. a connecting wire; 103. a rivet; 104. a chute; 1041. a guide part; 1042. a limit part; 105. a stapler; 1051. a through hole; 1052. a first sub-section of the stapler; 1053. a second part of the anastomat; 106. pushing the tube; 107. a circular tube portion; 108. an anchoring rib; 109. a puncture catheter; 110. a balloon; 111. a guidewire lumen; 112. a puncture needle lumen; 1121. a puncture needle outlet; 113. a liquid chamber; 114. a guide wire; 115. a puncture needle; 116. a fishing device; 117. a fishing ring; 118. a bendable catheter; 119. a first superhard guidewire; 120. a microcatheter; 121. a cutter; 122. a first soft guidewire; 131. a second superhard guidewire; 132. a second soft guidewire;

1. the left atrium; 2. a left ventricle; 3. a right ventricle; 4. right atrium; 5. a mitral valve; 6. an aortic valve; 7. superior vena cava; 8. inferior vena cava; 9. coronary sinus; 10. a curtain; 11. right fiber triangle; 12. left fiber triangle.

Detailed Description

The following description of the embodiments of the present invention will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the invention are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

In the description of the present invention, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.

In addition, the technical features of the different embodiments of the present invention described below may be combined with each other as long as they do not collide with each other.

Example 1

As shown in fig. 1, 2, 3, 4, is a preferred embodiment of the mitral valve repair device of the present invention.

In this embodiment, the mitral valve repair device comprises an implant 101, an anchor, and a connecting wire 102, the connecting wire 102 being used to connect the implant 101 and the anchor.

The implant 101 has a certain thickness, and the overall shape of the implant 101 can be an olive-shaped structure or a flat-sheet-shaped structure, so that the implant 101 can be more fit to the coronary sinus 9. In this embodiment, the implant 101 has an olive-shaped structure, specifically, a surface of the implant 101 contacting the coronary sinus 9 is a first arc surface, a surface of the implant 101 away from the coronary sinus 9 is a second arc surface, and the radian of the first arc surface is greater than that of the second arc surface. The implant 101 with the structure can be tightly attached to the coronary sinus 9 by the first arc surface, so that a good fixing effect is achieved, meanwhile, friction and pressure to blood vessels are reduced, and the implant 101 is more compact in structure by the second arc surface. The implant 101 may be made of a metal material or a polymer material, and in this embodiment, the implant 101 is made of a super-elastic alloy or a shape memory alloy material.

The interior of the implant 101 has a locking mechanism for locking the relative position between the implant 101 and the connection wire 102 such that the connection wire 102 cannot move relative to the implant 101.

The locking mechanism comprises at least one stage of sliding groove 104 formed on the inner wall of the implant 101 and a anastomat 105 matched with the sliding groove 104. The middle position of the second arc surface on the implant 101 is provided with a connecting line inlet 1011, one end of the implant 101 is provided with a connecting line outlet 1012, and the connecting line outlet 1012 is positioned close to the limit part 1042 according to the positions of the heart structure and the sliding groove 104. The chute 104 is communicated with the connecting line inlet 1011 and the connecting line outlet 1012, the side wall of the chute 104 is provided with a guide part 1041 and a limit part 1042, the limit part 1042 is positioned at one side close to the connecting line outlet 1012 and is perpendicular to the axis of the chute 104, and the guide part 1041 is obliquely arranged from the limit part 1042 to the axis. The anastomat 105 is provided with a through hole 1051 which is suitable for the connecting wire to pass through, and the extrusion action of the anastomat 105 on the guide part 1041 can reduce the aperture of the through hole 1051, thereby clamping the connecting wire 102, achieving the purpose of locking the connecting wire 102 and preventing the connecting wire 102 from being separated from the implant 101.

In this embodiment, the locking mechanism includes a plurality of stages of sliding grooves 104 arranged in a stepwise manner along an axis, and the positions of the guide portion 1041 and the limiting portion 1042 of the adjacent stages of sliding grooves 104 gradually approach the axis from the connecting line outlet 1012 to the connecting line inlet 1011. Specifically, the cross-sectional shape of each stage of the chute 104 is trapezoidal, and the upper bottom and the lower bottom of each chute 104 gradually decrease from the side of the connecting line outlet 1012, that is, the upper bottom and the lower bottom of the chute 104 closest to the connecting line outlet 1012 are the largest, and the upper bottom and the lower bottom of the chute 104 farthest from the connecting line outlet 1012 are the smallest, so that the purpose of unidirectional travel of the stapler 105 is achieved.

One end of each stage of sliding groove 104 facing the connecting line outlet 1012 is a limiting part 1042, the side wall of the sliding groove 104 is a guiding part 1041, the guiding part 1041 inclines from the limiting part 1042 to the axis of the sliding groove 104, that is to say, the guiding part 1041 intersects with the limiting part 1042 and the included angle is an acute angle, thereby realizing the purposes of locking the connecting line 102 by unidirectional movement of the anastomat 105 in the sliding groove 104 and preventing the connecting line 102 from moving randomly in the implant 101.

In this embodiment, the stapler 105 has a trapezoid shape matching the chute 104, and includes a first stapler part 1052 and a second stapler part 1053 that are axisymmetrically disposed with respect to the through hole 1051, where opposite surfaces of the first stapler part 1052 and the second stapler part 1053 together form the through hole 1051, that is, opposite surfaces of the first stapler part 1052 and the second stapler part 1053 are inner walls of the through hole 1051. The inner wall of the through hole 1051 is formed with clamping teeth, and the clamping teeth are in contact fit with the outer wall of the connecting wire 102, so as to enhance the contact friction force between the anastomat 105 and the connecting wire 102, firmly lock the connecting wire 102 and prevent the connecting wire 102 from slipping. The stapler 105 may be made of a metal material or a polymer material, and in this embodiment, the stapler 105 is made of a super elastic alloy or a shape memory alloy material. In this embodiment, the stapler first section 1052 and the stapler second section 1053 are provided separately.

In this embodiment, the mitral valve repair device further comprises a pushing tube 106 sleeved on the connecting wire 102, wherein one end of the pushing tube 106 can be inserted into the connecting wire outlet 1012, and the end can push the anastomat 105 to travel along the guiding part 1041, in the process, the guiding part 1041 presses the outer wall of the anastomat 105 to reduce the aperture of the through hole 1051 until the connecting wire 102 is clamped, so that the position of the connecting wire 102 and the position of the implant 101 are relatively fixed.

As shown in fig. 5, the anchor includes a rivet 103, and the rivet 103 is fixedly connected to one end of the connection wire 102. The rivet 103 includes a cylindrical circular tube portion 107 and anchor ribs 108, the circular tube portion 107 is fixedly connected with the connecting wire 102, one end of the rivet 103 facing the connecting wire 102 (i.e., one end of the circular tube portion 107 facing the connecting wire 102) is provided with a plurality of anchor ribs 108 which are outwards opened and uniformly distributed along the circumference, the anchor ribs 108 are arc-shaped structures, the free ends of the anchor ribs 108 are bent in a direction away from the implant 101, and in this embodiment, the number of the anchor ribs 108 is 4. This structural design enables the rivets 103 to be securely placed on the shade 10, enhancing the stability of the installation of the rivets 103. The anchor rib 108 is made of a metal material or a polymer material, and in this embodiment, the anchor rib 108 is made of a super elastic alloy or a shape memory alloy material.

As shown in fig. 6, 7, 8, 9, 10, 12 and 13, in this embodiment, the mitral valve repair device further includes a puncture catheter 109, wherein a puncture needle cavity 112, a guide wire cavity 111 and a liquid cavity 113 are formed inside the puncture catheter 109 along the length direction thereof, the puncture needle cavity 112 has a puncture needle outlet 1121 on one side wall of the puncture catheter 109, and the puncture needle cavity 112 has a corner with an angle between 90 ° and 150 ° at the puncture needle outlet 1121, so as to facilitate the puncture needle 115 to smoothly penetrate out of the puncture needle outlet 1121. In this embodiment, the angle at the needle outlet 1121 is 150 °, and a larger obtuse angle can prevent the needle 115 from puncturing the catheter 109. The other side wall of the puncture catheter 109 is provided with a compliant or non-compliant balloon 110, and the liquid cavity 113 is communicated with the balloon 110, and contrast medium is injected into the balloon 110 through the liquid cavity 113, so that the balloon 110 can be inflated, and the puncture catheter can be supported and fixed.

As shown in fig. 11, in this embodiment, the mitral valve repair device further comprises a catcher 116, one end of the catcher 116 having at least one catcher ring 117 adapted to catch the connecting wire 102, in this embodiment 4 catcher rings 117 are used. The catcher 116 is made of a metal material or a polymer material, and in this embodiment, the catcher 116 is made of a super elastic alloy and a shape memory alloy material.

The following describes an operation procedure of performing a mitral valve repair operation using the mitral valve repair device provided by the present invention:

as shown in fig. 14, the atrial septum between the left atrium 1 and the right atrium 4 is first penetrated using the associated instruments and standard methods: the flexible catheter 118 is passed from the femoral vein into the inferior vena cava 8 and then through the atrial septum into the left atrium 1, and the curved end of the flexible catheter 118 is aligned with the curtain 10 or the upper region of the left fiber triangle 12 or the right fiber triangle 11 or other mitral valve 5 between the aortic valve 6 and the mitral valve 5 using ultrasonic means, in this embodiment the curved end of the flexible catheter 118 is aligned with the curtain 10.

15, 16, 17, 18 and 19, one end of the first superhard guide wire 119 drives the rivet 103 to align with the position of the curtain 10 along the bendable guide tube 118, one end of the connecting wire 102 is connected to the rivet 103, the other end of the connecting wire 102 is connected with the first soft guide wire 122, the connecting wire is in a U-shaped state in the bendable guide tube 118, then the rivet 103 penetrates through the curtain 10 and enters the left ventricle 2, then the anchoring rib 108 of the rivet 103 is unfolded, the anchoring rib 108 is clamped at the position of the curtain 10, and the rivet 103 is fixed on the curtain 10; a portion of the flexible catheter 118 is then withdrawn, exposing the connecting wire 102 and the first flexible guidewire 122 to the left atrium 1.

As shown in fig. 20 and 21, the guide wire 114 is inserted into the guide wire cavity 111 of the puncture catheter 109, wherein the diameter of the guide wire 114 is 0.035 mm, the guide wire 114 is inserted into the human body from the jugular vein, the guide wire 114 enters the right atrium 4 along the superior vena cava 7, then reaches the right ventricle 3, and finally enters the coronary sinus 9, the puncture catheter 109 enters a designated position in the coronary sinus 9 along the guide of the guide wire 114, the mitral valve 5 is D-shaped from the bottom view, and the end portion of the puncture catheter 109 faces the short axis direction of the mitral valve 5.

As shown in fig. 22, a contrast medium is injected into the balloon 110 through the liquid chamber 113 by an external pump, and the balloon 110 is inflated until the balloon 110 abuts against the inner wall of the coronary sinus 9, thereby achieving the position fixation of the puncture catheter 109.

As shown in fig. 23, the puncture needle 115 is inserted into the puncture catheter 109 along the puncture needle cavity 112, the puncture needle 115 penetrates the coronary sinus 9 and enters the left atrium 1, wherein the puncture needle 115 is made of flexible metal, and the puncture needle 115 is of a cavity structure and can deform along with the shape of the puncture needle cavity 112.

As shown in fig. 24, the catcher 116 is introduced into the left atrium 1 from the lumen of the puncture needle 115, and the catcher 116 is also introduced into the left atrium 1 with the aid of the catcher ring 117 at the distal end, and the connecting wire 102 located in the left atrium 1 is grasped by the catcher ring 117, as shown in fig. 25 in a side view. The first flexible guide wire 122 is provided for the purpose of precise catching of the connecting wire 102 by the catcher 116.

As shown in fig. 26, the catcher 116 pulls the connecting wire 102 into the lumen of the puncture needle 115.

As shown in fig. 27, the connecting wire 102 is finally pulled out of the puncture catheter 109 and placed outside the heart.

As shown in fig. 28, the contrast medium in balloon 110 is expelled, causing balloon 110 to deflate.

As shown in fig. 29, the puncture catheter 109 is removed from the coronary sinus 9.

The connecting wire 102 is threaded outside the heart into the connecting wire inlet 1011 and thus into the interior of the implant 101. As shown in fig. 30, the microcatheter 120 is advanced along the connecting wire 102 to the implant 101 into the coronary sinus 9.

As shown in fig. 31, the push tube 106 is inserted into the microcatheter 120 and thus into the connection line outlet 1012 of the implant 101, and the push tube 106 pushes the implant 101 until the implant 101 reaches the prescribed position in the coronary sinus 9. In the process, the pushing tube 106 pushes the anastomat 105 to travel along the guide part 1041, the guide part 1041 presses the outer wall of the anastomat 105 inwards, the first anastomat part 1052 and the second anastomat part 1053 are close to each other, the aperture of the through hole 1051 of the anastomat is reduced, the anastomat 105 gradually clamps the connecting wire 102 until the anastomat 105 completely clamps the connecting wire 102, and the position locking between the connecting wire 102 and the implant 101 is realized.

As shown in fig. 32, the connecting wire 102 is pulled taut for the purpose of contracting the short axis of the mitral valve 5.

As shown in fig. 33, the excess connecting wire 102 exposed outside the coronary sinus 9 is cut off by the cutter 121, and then the cutter 121 is withdrawn.

As shown in fig. 34, the entire device operation process is completed, and the final state is presented.

Example two

As shown in fig. 39, 40, 41, the mitral valve repair device of the present embodiment differs from the first embodiment in that: the locking mechanism comprises a primary chute 104 formed on the inner wall of the implant 101 and a stapler 105 matched with the chute 104. In this embodiment, the stapler 105 has elasticity and is of an integrally formed structure, and the inner wall of the stapler 105 has clamping teeth. The primary chute 104 is matched with the anastomat 105, so that the processing difficulty can be reduced, and the processing cost can be saved.

Example III

As shown in fig. 35, the mitral valve repair device of the present embodiment differs from the first embodiment in that: the rivet 103 is in a straight shape, and has a length of 5-15 mm, preferably 10 mm, and a width of 1-5 mm, preferably 2.5 mm. The in-line rivet 103 can reduce the processing difficulty. Such rivets 103 may be made from polymeric materials, stainless steel, cobalt-based alloys, or nickel-titanium alloy materials.

As shown in fig. 36, 37 and 38, when performing a repair operation using the mitral valve repair device of the present embodiment, the second superhard guide wire 131 is used to directly penetrate the curtain 10, and then the rivet 103 is inserted through the curtain 10, and the second soft guide wire 132 is also connected to the rivet 103. Thereby reducing the difficulty of operation, reducing the number of operation steps, and facilitating the fishing of the connecting line 102.

It is apparent that the above examples are given by way of illustration only and are not limiting of the embodiments. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. While still being apparent from variations or modifications that may be made by those skilled in the art are within the scope of the invention.

Claims

1. A mitral valve repair device, characterized by: the device comprises an implant (101), an anchor and a connecting wire (102) for connecting the implant (101) and the anchor, wherein a locking mechanism for fixing the relative positions of the implant (101) and the connecting wire (102) is arranged inside the implant (101).

2. The mitral valve repair device of claim 1, wherein: the locking mechanism comprises at least one stage of sliding groove (104) formed on the inner wall of the implant (101) and an anastomat (105) matched with the sliding groove (104), the sliding groove (104) is communicated with a connecting wire inlet (1011) and a connecting wire outlet (1012) of the implant (101), the sliding groove (104) is provided with a guide part (1041) and a limit part (1042), the limit part (1042) is positioned at one side close to the connecting wire outlet (1012) and is perpendicular to the axis of the sliding groove (104), and the guide part (1041) is obliquely arranged from the limit part (1042) to the axis; the stapler (105) has a through hole (1051) adapted to the connection line (102) to pass through, and the stapler (105) is pressed by the guide portion (1041) to reduce the aperture of the through hole (1051).

3. The mitral valve repair device of claim 2, wherein: the locking mechanism comprises a plurality of stages of sliding grooves (104) which are arranged in a step-like manner along the axis, and the arrangement positions of the guide parts (1041) and the limit parts (1042) of the sliding grooves (104) of adjacent stages gradually approach the axis from the connecting wire outlet (1012) to the connecting wire inlet (1011).

4. A mitral valve repair device as claimed in claim 3, wherein: the stapler (105) comprises a first stapler part (1052) and a second stapler part (1053) axially symmetrical with respect to the through hole (1051); clamping teeth are formed on the inner walls of the first anastomotic component (1052) and the second anastomotic component (1053).

5. The mitral valve repair device of claim 4, wherein: the first stapler part (1052) and the second stapler part (1053) are elastic and integrally formed.

6. The mitral valve repair device of claim 2, wherein: the stapler also comprises a pushing tube (106) sleeved on the connecting wire (102), and one end of the pushing tube (106) is inserted into the connecting wire outlet (1012) and can push the stapler (105) to move along the guide part (1041).

7. The mitral valve repair device of claim 1, wherein: the implant (101) is of olive-type or flat-sheet type construction.

8. The mitral valve repair device of claim 1, wherein: the anchoring piece comprises a rivet (103), the rivet (103) is fixedly connected with one end of the connecting wire (102), and a plurality of outwards-opened anchoring ribs (108) are arranged at one end of the rivet (103) facing the connecting wire (102).

9. The mitral valve repair device of claim 8, wherein: the anchoring ribs (108) are of arc-shaped structures, the free ends of the anchoring ribs (108) are bent in the direction away from the implant (101), and the anchoring ribs (108) are uniformly distributed along the circumferential direction.

10. The mitral valve repair device of any one of claims 1-9, wherein: the novel puncture catheter comprises a puncture catheter (109) and a catcher (116), wherein a puncture needle cavity (112), a guide wire cavity (111) and a liquid cavity (113) are formed in the puncture catheter (109) along the length direction of the puncture catheter, the puncture needle cavity (112) is provided with a puncture needle outlet (1121) on one side wall of the puncture catheter (109), a balloon (110) is arranged on the other side wall of the puncture catheter (109), and the liquid cavity (113) is communicated with the balloon (110); the fishing device (116) has at one end at least one fishing ring (117), the fishing ring (117) being adapted to grip the connecting line (102).