CN116919365A - Blood pressure calibration system, blood pressure calibration method and device thereof - Google Patents

Blood pressure calibration system, blood pressure calibration method and device thereof Download PDF

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Publication number
CN116919365A
CN116919365A CN202210357036.XA CN202210357036A CN116919365A CN 116919365 A CN116919365 A CN 116919365A CN 202210357036 A CN202210357036 A CN 202210357036A CN 116919365 A CN116919365 A CN 116919365A
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blood pressure
pressurization
pressure value
ppg
user
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严家兵
黄振龙
何小祥
何刚
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Huawei Technologies Co Ltd
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Huawei Technologies Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/022Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/022Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02233Occluders specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/7475User input or interface means, e.g. keyboard, pointing device, joystick
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0223Operational features of calibration, e.g. protocols for calibrating sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247Pressure sensors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

The application discloses a blood pressure calibration system, a blood pressure calibration method and a device thereof, which can improve the accuracy of blood pressure measurement in a state of large blood pressure fluctuation. A blood pressure calibration method is applied to a blood pressure measuring device worn on a first part of a human body. The pressurizing device is used for being worn on a second part of the human body different from the first part. The blood pressure calibration method comprises the following steps: acquiring a blood pressure value of a user; if the user blood pressure value is an abnormal blood pressure value, determining one or more pressure values according to prestored PPG model parameters and the abnormal blood pressure value, wherein the one or more pressure values comprise a first pressure value; transmitting a first pressurization notification including a first pressure value to the pressurization device; receiving a first pressurization completion signal sent by the pressurization device, the first pressurization completion signal being used for informing the blood pressure measurement device that the pressurization device has completed pressurization according to the first pressure value; in response to the first pressurization completion signal, acquiring a first blood pressure value and a first PPG signal; the first blood pressure value and the first PPG signal are stored.

Description

Blood pressure calibration system, blood pressure calibration method and device thereof
Technical Field
The application relates to the field of terminals, in particular to a blood pressure calibration system, a blood pressure calibration method and a device thereof.
Background
Hypertension is a common chronic disease and is also a major risk factor for cardiovascular and cerebrovascular diseases. About 2 hundred million of patients with hypertension in China, 23% of adults suffer from hypertension, 70% of cerebral strokes and 50% of myocardial death are related to hypertension. Currently, blood pressure can be measured by a blood pressure measurement method. Photoplethysmographic (PPG) technology is a common blood pressure measurement method. The PPG technology detects the difference of reflected light intensities after absorption by blood passing through peripheral micro blood vessels and human tissues during heart beating according to the pulsatility change of the blood volume of the peripheral micro blood vessels of a human body along with the heart beating by a PPG blood pressure measuring device, records the change of the blood volume during heart beating to obtain a pulse waveform, and determines blood pressure according to the obtained pulse waveform. However, due to body movement noise of the human body, external interference light, sweat of the human body, and other noises, the accuracy of the blood pressure measured by the PPG technology is low. In order to improve the accuracy of PPG technical measurements, the PPG blood pressure measurement device needs to be calibrated. However, when the blood pressure fluctuation is large, such as when the patient takes medicine, the blood pressure measured by the current blood pressure calibration method is inaccurate.
Disclosure of Invention
In view of the foregoing, it is desirable to provide a blood pressure calibration system, a blood pressure calibration method, and a device thereof, which can improve the accuracy of blood pressure measurement in a state where blood pressure fluctuation is large.
In a first aspect, an embodiment of the present application provides a blood pressure calibration system, the blood pressure calibration system including a blood pressure measurement device and a pressurization device, the blood pressure measurement device being communicatively connected to the pressurization device, the blood pressure measurement device being configured to be worn on a first portion of a human body, the pressurization device being configured to be worn on a second portion of the human body, the second portion being different from the first portion, the blood pressure measurement device pre-storing PPG model parameters, wherein: the blood pressure measuring device is used for acquiring a blood pressure value of a user; if the user blood pressure value is an abnormal blood pressure value, the blood pressure measurement device is further configured to determine one or more pressure values according to the PPG model parameter and the abnormal blood pressure value, where the one or more pressure values include a first pressure value; the blood pressure measurement device is further configured to send a first pressurization notification to the pressurization device, the first pressurization notification including the first pressure value; in response to the first pressurization notification, the pressurization device is configured to perform pressurization according to the first pressure value, and send a first pressurization completion signal to the blood pressure measurement device after the pressurization is completed; in response to the first pressurization complete signal, the blood pressure measurement device is further configured to measure a first blood pressure value and acquire a first PPG signal; the blood pressure measurement device is further configured to store the first blood pressure value and the first PPG signal.
According to the first aspect of the application, one or more pressure values including a first pressure value are determined according to PPG model parameters and abnormal blood pressure values through a blood pressure measuring device, and after a first pressurization notification is received, the first pressurization notification including the first pressure value is sent to a pressurizing device, the pressurizing device applies corresponding pressure to a second part of a user according to the first pressure value to adjust the blood pressure of the first part of the user, and after pressurization is completed, a first pressurization completion signal is sent to the blood pressure measuring device, the blood pressure measuring device can respond to the first pressurization completion signal to measure and store the blood pressure value and the PPG signal, so that the pressurizing device starts pressurization after receiving the pressurization notification of the blood pressure measuring device, and the blood pressure measuring device starts measurement after receiving the pressurization completion signal sent by the pressurizing device, thereby ensuring the accuracy of measurement, ensuring the high accuracy of blood pressure and PPG signal, and improving the accuracy of subsequent blood pressure measurement; meanwhile, the blood pressure value and the PPG signal corresponding to the blood pressure can be obtained, the data which are not in the parameters of the PPG model can be obtained, the PPG model can be used in a larger blood pressure measuring range, the accuracy of blood pressure measurement under the condition of large blood pressure fluctuation can be improved, meanwhile, the data which are not in the PPG model can be supplemented according to the blood pressure condition of the user due to the consideration of the abnormal blood pressure value of the user, and the accuracy of blood pressure measurement is further improved when the blood pressure of the user is measured subsequently.
According to some embodiments of the application, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value; after the blood pressure measuring device finishes measuring the first blood pressure value and acquiring the first PPG signal, the blood pressure measuring device is further configured to send a second pressurization notification to the pressurization device, where the second pressurization notification includes the second pressure value; in response to the second pressurization notification, the pressurization device is configured to perform pressurization according to the second pressure value, and send a second pressurization completion signal to the blood pressure measurement device after the pressurization is completed; in response to the second pressurization completion signal, the blood pressure measurement device is further configured to measure a second blood pressure value and acquire a second PPG signal; the blood pressure measurement device is further configured to store the second blood pressure value and the second PPG signal. According to the application, the first pressurization notification comprises the first pressure value, the second pressurization notification comprises the second pressure value, so that the blood pressure measuring device can sequentially send the pressure value to the pressurization equipment, the pressurization equipment can sequentially pressurize according to the sequence from the large pressure value to the small pressure value through the second pressure value being larger than the first pressure value, discomfort to the body of a user is avoided, meanwhile, more data which are not contained in PPG model parameters can be obtained, and the accuracy of blood pressure measurement under the condition of large blood pressure fluctuation can be further improved.
According to some embodiments of the application, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value; the first pressurization notification includes the first pressure value and the second pressure value; the blood pressure measuring device is further configured to send a second pressurization notification to the pressurization device after the blood pressure measuring device finishes measuring the first blood pressure value and acquiring the first PPG signal; in response to the second pressurization notification, the pressurization device is configured to perform pressurization according to the second pressure value, and send a second pressurization completion signal to the blood pressure measurement device after the pressurization is completed; in response to the second pressurization completion signal, the blood pressure measurement device is further configured to measure a second blood pressure value and acquire a second PPG signal; the blood pressure measurement device is further configured to store the second blood pressure value and the second PPG signal. According to the application, the first pressurization notification comprises the first pressure value and the second pressure value, the second pressurization notification does not comprise the pressure value, so that the blood pressure measuring device can send the pressure value to the pressurizing device at one time, the pressurizing device can be gradually pressurized according to the sequence from the large pressure value to the small pressure value through the second pressure value being larger than the first pressure value, discomfort to the body of a user is avoided, meanwhile, more data which are not contained in PPG model parameters can be obtained, and the accuracy of blood pressure measurement under the condition of large blood pressure fluctuation can be further improved.
According to some embodiments of the application, the user blood pressure value is obtained for a blood pressure measuring device from the pressurizing apparatus, or is obtained for the blood pressure measuring device by a PPG detection unit measurement, or is obtained for the blood pressure measuring device by a micropump and a balloon measurement. The blood pressure value of the user can be measured by the pressurizing equipment, or the PPG detection unit of the blood pressure measuring device, or the micro pump and the air bag, so that a plurality of different blood pressure acquisition modes can be realized.
According to some embodiments of the application, the blood pressure measuring device is further configured to update a PPG model according to all stored blood pressure values and PPG signals; the blood pressure measuring device is also used for measuring the blood pressure of the user according to the updated PPG model. The application can utilize the stored blood pressure value and the PPG signal to measure the blood pressure of the user, thereby improving the accuracy of blood pressure measurement.
According to some embodiments of the application, the first portion is a wrist and the second portion is an upper arm. By applying pressure on the upper arm, arterial blood which is approximately consistent with the output of the heart can be obtained when the blood pressure is measured at the wrist, more accurate blood pressure value and PPG signal can be obtained, and the accuracy of the subsequent blood pressure measurement is improved.
According to some embodiments of the application, the blood pressure measurement device comprises a micropump, a balloon, and a PPG sensor; in response to the first pressurization completion signal, the blood pressure measurement device is further configured to control the micropump to inflate the bladder to measure the first blood pressure value; the blood pressure measurement device is further configured to acquire the first PPG signal via the PPG sensor after the balloon deflation is completed. The application obtains the first blood pressure value through the micropump and the balloon, and can obtain a more accurate first blood pressure value.
According to some embodiments of the application, after the blood pressure measuring device determines one or more pressure values according to the PPG model parameter and the abnormal blood pressure value, the blood pressure measuring device is further configured to display a first pressurization prompting interface, where the first pressurization prompting interface is configured to prompt to start pressurization; the blood pressure measuring device is also used for receiving a first confirmation operation of a user; in response to a first confirmation operation by the user, the blood pressure measurement device is further configured to send the first pressurization notification to the pressurization device; the first pressurization notification is for notifying the pressurization device to pressurize according to the first pressure value. The blood pressure measuring device displays the pressurization prompt interface to prompt the start of pressurization, so that the user operation can be prompted, and the blood pressure measuring device sends the first pressurization notification to the pressurization equipment in response to the user operation, so that the user can confirm and then send the first pressurization notification.
According to some embodiments of the application, the blood pressure measuring device is further configured to determine one or more calibrated blood pressure values from the PPG model parameter and the abnormal blood pressure value; the blood pressure measuring device is further used for determining one or more pressure values according to one or more calibration blood pressure values, and each calibration blood pressure value corresponds to one pressure value. The application can realize the determination of the pressure value by determining one or more blood pressure states required by the blood pressure measuring device according to the PPG model parameters and the abnormal blood pressure values and determining the pressure value to be applied by the pressurizing equipment according to the one or more blood pressure states required by the blood pressure measuring device.
In a second aspect, an embodiment of the present application further provides a blood pressure calibration method applied to a blood pressure measurement device and a pressurization device, where the blood pressure measurement device is communicatively connected to the pressurization device, the blood pressure measurement device is used for being worn on a first part of a human body, the pressurization device is used for being worn on a second part of the human body, and the second part is different from the first part, and the method includes: the blood pressure measuring device acquires a blood pressure value of a user; if the user blood pressure value is an abnormal blood pressure value, the blood pressure measuring device determines one or more pressure values according to a pre-stored PPG model parameter and the abnormal blood pressure value, wherein the one or more pressure values comprise a first pressure value; the blood pressure measurement device sending a first pressurization notification to the pressurization device, the first pressurization notification including the first pressure value; in response to the first pressurization notification, the pressurization device performs pressurization according to the first pressure value, and transmits a first pressurization completion signal to the blood pressure measurement device after the pressurization is completed; in response to the first pressurization complete signal, the blood pressure measurement device measures a first blood pressure value and acquires a first PPG signal; the blood pressure measurement device stores the first blood pressure value and the first PPG signal.
According to some embodiments of the application, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value; after the blood pressure measuring device finishes measuring the first blood pressure value and acquiring the first PPG signal, the blood pressure measuring device is further configured to send a second pressurization notification to the pressurization device, where the second pressurization notification includes the second pressure value; in response to the second pressurization notification, the pressurization device is configured to perform pressurization according to the second pressure value, and send a second pressurization completion signal to the blood pressure measurement device after the pressurization is completed; in response to the second pressurization completion signal, the blood pressure measurement device is further configured to measure a second blood pressure value and acquire a second PPG signal; the blood pressure measurement device is further configured to store the second blood pressure value and the second PPG signal.
According to some embodiments of the application, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value; the first pressurization notification includes the first pressure value and the second pressure value; the blood pressure measuring device is further configured to send a second pressurization notification to the pressurization device after the blood pressure measuring device finishes measuring the first blood pressure value and acquiring the first PPG signal; in response to the second pressurization notification, the pressurization device is configured to perform pressurization according to the second pressure value, and send a second pressurization completion signal to the blood pressure measurement device after the pressurization is completed; in response to the second pressurization completion signal, the blood pressure measurement device is further configured to measure a second blood pressure value and acquire a second PPG signal; the blood pressure measurement device is further configured to store the second blood pressure value and the second PPG signal.
According to some embodiments of the application, the user blood pressure value is obtained for a blood pressure measuring device from the pressurizing apparatus, or for the blood pressure measuring device by a PPG detection unit of the blood pressure measuring device, or for the blood pressure measuring device by a micropump and a balloon of the blood pressure measuring device.
According to some embodiments of the application, the blood pressure measuring device is further configured to update a PPG model according to all stored blood pressure values and PPG signals; the blood pressure measuring device is also used for measuring the blood pressure of the user according to the updated PPG model.
According to some embodiments of the application, the first portion is a wrist and the second portion is an upper arm.
According to some embodiments of the application, the blood pressure measurement device comprises a micropump, a balloon, and a PPG sensor; in response to the first pressurization completion signal, the blood pressure measurement device is further configured to control the micropump to inflate the bladder to measure the first blood pressure value; the blood pressure measurement device is further configured to acquire the first PPG signal via the PPG sensor after the balloon deflation is completed.
According to some embodiments of the application, the sending a first pressurization notification to the pressurization device comprises: the blood pressure measuring device displays a first pressurization prompting interface, and the first pressurization prompting interface is used for prompting the start of pressurization; the blood pressure measuring device receives a first confirmation operation of a user; in response to a first confirmation operation by the user, the blood pressure measurement device transmits the first pressurization notification to the pressurization device; the first pressurization notification is for notifying the pressurization device to pressurize according to the first pressure value.
According to some embodiments of the application, the determining one or more pressure values by the blood pressure measurement device from pre-stored PPG model parameters and the abnormal blood pressure values comprises: the blood pressure measuring device determines one or more calibration blood pressure values according to the PPG model parameters and the abnormal blood pressure values; the blood pressure measuring device determines one or more pressure values according to one or more calibration blood pressure values, wherein each calibration blood pressure value corresponds to one pressure value.
In a third aspect, an embodiment of the present application further provides a blood pressure calibration method applied to a blood pressure measurement device, where the blood pressure measurement device is configured to be worn on a first portion of a human body, the blood pressure measurement device is configured to be communicatively connected to a pressurizing device, where the pressurizing device is configured to be worn on a second portion of the human body, and the second portion is different from the first portion, and the method includes: acquiring a blood pressure value of a user; if the user blood pressure value is an abnormal blood pressure value, determining one or more pressure values according to a prestored PPG model parameter and the abnormal blood pressure value, wherein the one or more pressure values comprise a first pressure value; transmitting a first pressurization notification to the pressurization device, the first pressurization notification including the first pressure value; the first pressurization notification is used for notifying the pressurization device to pressurize according to the first pressure value; receiving a first pressurization completion signal sent by the pressurization device, the first pressurization completion signal being used for informing the blood pressure measurement device that the pressurization device has completed pressurization according to the first pressure value; measuring a first blood pressure value and acquiring a first PPG signal in response to the first pressurization complete signal; the first blood pressure value and the first PPG signal are stored.
According to some embodiments of the application, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value, the method further comprising: after ending measuring the first blood pressure value and acquiring the first PPG signal, sending a second pressurization notification to the pressurization device, the second pressurization notification comprising the second pressure value; the second pressurization notification is used for notifying the pressurization device to pressurize according to the second pressure value; receiving a second pressurization completion signal sent by the pressurization device, the second pressurization completion signal being used to inform the blood pressure measurement apparatus that the pressurization device has completed pressurization according to the second pressure value; measuring a second blood pressure value and acquiring a second PPG signal in response to the second pressurization complete signal; the second blood pressure value and the second PPG signal are stored.
According to some embodiments of the application, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value, the first pressurization notification comprising the first pressure value and the second pressure value, the method further comprising: after ending measuring the first blood pressure value and acquiring the first PPG signal, sending a second pressurization notification to the pressurization device; the second pressurization notification is used for notifying the pressurization device to pressurize according to the second pressure value; receiving a second pressurization completion signal sent by the pressurization device, the second pressurization completion signal being used to inform the blood pressure measurement apparatus that the pressurization device has completed pressurization according to the second pressure value; measuring a second blood pressure value and acquiring a second PPG signal in response to the second pressurization complete signal; the second blood pressure value and the second PPG signal are stored.
According to some embodiments of the application, the obtaining the user blood pressure value comprises: acquiring a user blood pressure value from the pressurizing device; or the PPG detection unit of the blood pressure measuring device is used for measuring and obtaining the blood pressure value of the user; or the blood pressure value of the user is obtained through the micropump and the balloon measurement of the blood pressure measuring device.
According to some embodiments of the application, the method further comprises: updating the PPG model according to all stored blood pressure values and PPG signals; and measuring the blood pressure of the user according to the updated PPG model.
According to some embodiments of the application, the first portion is a wrist and the second portion is an upper arm.
According to some embodiments of the application, measuring a first blood pressure value and acquiring a first PPG signal in response to the first pressurization complete signal comprises: controlling a micropump of the blood pressure measurement device to inflate a bladder of the blood pressure measurement device to measure the first blood pressure value in response to the first pressurization completion signal; after the balloon is deflated, the first PPG signal is acquired by a PPG sensor of the blood pressure measuring device.
According to some embodiments of the application, the sending a first pressurization notification to the pressurization device comprises: displaying a first pressurization prompt interface, wherein the first pressurization prompt interface is used for prompting the start of pressurization; receiving a first confirmation operation of a user; the first pressurization notification is sent to the pressurization device in response to a first confirmation operation by the user.
According to some embodiments of the application, the determining one or more pressure values from pre-stored PPG model parameters and the abnormal blood pressure value comprises: determining one or more calibrated blood pressure values according to the PPG model parameters and the abnormal blood pressure values; one or more of the pressure values are determined from one or more of the calibrated blood pressure values, one for each calibrated blood pressure value.
In a fourth aspect, an embodiment of the present application further provides a blood pressure measurement device, the blood pressure measurement device including at least one processor, a memory, and a communication interface; the at least one processor is coupled with the memory and the communication interface; the memory is used for storing instructions, the processor is used for executing the instructions, and the communication interface is used for communicating with the pressurizing device under the control of the at least one processor; the instructions, when executed by the at least one processor, cause the at least one processor to perform the method as described above for any one of the possible embodiments of the third aspect.
In a fifth aspect, an embodiment of the application also provides a computer storage medium comprising computer instructions which, when run on a blood pressure measurement device, cause the blood pressure measurement device to perform the method as described above in any one of the possible embodiments of the third aspect.
In a sixth aspect, an embodiment of the application also provides a computer program product comprising program code for implementing a method as described in any of the possible embodiments of the third aspect above, when the program code is executed by a processor in a blood pressure measuring device. The advantages of the second to sixth aspects and various implementations of the present application may refer to the first aspect and various implementations thereof, and the analysis of the advantages of the first aspect, which are not described herein.
Drawings
Fig. 1 is a schematic diagram of a prior art blood pressure measurement.
Fig. 2 is a schematic diagram of a blood pressure calibration system according to an embodiment of the present application.
Fig. 3 is a schematic physical structure of a pressurizing device according to an embodiment of the present application.
Fig. 4 is a schematic physical structure diagram of a blood pressure measurement device according to an embodiment of the present application.
Fig. 5 is a schematic diagram of another physical structure of a blood pressure measurement device according to an embodiment of the present application.
Fig. 6 is a flowchart of a blood pressure calibration method according to an embodiment of the present application.
FIG. 7 is a schematic diagram of an interface for accurately entering a calibration state according to an embodiment of the present application.
FIG. 8 is an interface diagram illustrating an accurate calibration state according to another embodiment of the present application.
Fig. 9 is a schematic diagram of multi-point calibration according to an embodiment of the present application.
FIG. 10A is a schematic diagram of a pulse oscillation wave signal according to an embodiment of the present application; fig. 10B is a schematic diagram of a PPG signal according to an embodiment of the present application.
FIG. 11A is a diagram showing the measured blood pressure value and the actual blood pressure value after calibration by the prior art calibration method; fig. 11B is a schematic diagram of a blood pressure value measured after calibration by the blood pressure calibration method according to the present application and a real blood pressure value.
Fig. 12 is a schematic diagram of another blood pressure calibration system according to an embodiment of the present application.
Fig. 13 is a flowchart of another blood pressure calibration method according to an embodiment of the present application.
Detailed Description
In describing embodiments of the present application, words such as "for example" are used to indicate examples, illustrations or descriptions. Any embodiment or design described herein as "for example" in embodiments of the application should not be construed as preferred or advantageous over other embodiments or designs. Rather, the use of words such as "for example" is intended to present related concepts in a concrete fashion.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. It should be understood that in the present application, unless otherwise indicated, "a plurality" means two or more than two.
The prior art provides a blood pressure calibration method, which can calibrate a PPG blood pressure measuring device by using an external blood pressure measuring device by using an oscillometric method at preset periods in the process of using the PPG blood pressure measuring device for the first time or using the PPG blood pressure measuring device. In the existing blood pressure calibration method, during the period of acquiring a plurality of PPG signals in a short time, an external blood pressure measuring device is utilized to acquire a plurality of accurate blood pressure values by adopting an oscillometric method for a plurality of times. Each PPG signal corresponds to a more accurate blood pressure value. The existing blood pressure calibration method also utilizes each PPG signal and a corresponding relatively accurate blood pressure value to form a piece of calibration data, and utilizes the calibration data to calibrate the PPG model for measuring blood pressure. However, when the blood pressure fluctuation is large, such as when the patient takes medicine, the blood pressure measured by the current blood pressure calibration method is inaccurate, as shown in fig. 1. In fig. 1, a broken line indicates the blood pressure measured by the PPG blood pressure measuring device, a solid line indicates the actual blood pressure of the patient with hypertension, a point a indicates the measurement start immediately after the PPG model is calibrated, and a point B indicates the measurement start immediately after the patient with hypertension takes the medicine. After the patient with hypertension takes the medicine, the calibrated PPG model will fail due to the large fluctuation of the blood pressure relative to the blood pressure when the PPG model is calibrated, which will cause the difference between the blood pressure value measured by the PPG blood pressure measuring device and the actual blood pressure value of the patient with hypertension to be large, so that the PPG blood pressure measurement is inaccurate, as shown in fig. 1.
Therefore, the embodiment of the application provides a blood pressure calibration method, which can improve the accuracy of blood pressure measurement in a state of large blood pressure fluctuation.
Referring to fig. 2, a schematic diagram of a blood pressure calibration system according to an embodiment of the present application is provided. As shown in fig. 2, the blood pressure calibration system 20 includes a pressurizing device 21 and a blood pressure measuring apparatus 22. The pressurizing device 21 may be used to compress against the arterial vessel area of the user. In fig. 2, the pressurizing device 21 may be circumferentially arranged on the upper arm of the user for compressing the brachial artery of the user by pressurizing the brachial artery. Although only the compression device 21 is shown in fig. 2 as being compressed against the upper arm of the user, it will be appreciated that the compression device 21 may also be compressed against the forearm of the user, etc., as the application is not limited in this regard. For convenience of description, the pressurizing device 21 is set around the upper arm of the user as an example for simplicity of description. The pressurizing device 21 may be a cuff device or a belt device or the like. The pressurizing device 21 may have a blood pressure measurement function. The blood pressure measuring device 22 may be disposed around a portion to be detected of the user, such as the wrist shown in fig. 2, and the portion to be detected is not limited by the present application. For convenience of description, the blood pressure measuring device 22 is described below for example as being disposed around the wrist of the user. The blood pressure measuring device 22 may be a wearable blood pressure meter, such as a smart watch, smart bracelet, etc. having blood pressure measuring functions. The blood pressure measuring device 22 may be a sphygmomanometer including a PPG measurement function and an oscillation method measurement function. The blood pressure measuring device 22 is used to acquire a PPG signal and a blood pressure value.
In one possible implementation, the blood pressure measuring device 22 may be communicatively connected to the pressurizing device 21. The blood pressure measuring device 22 may be connected to the pressurizing device 21 wirelessly. The wireless mode can be Bluetooth mode, wifi mode or the like, and the wireless mode is not limited by the application. If the user blood pressure value is an abnormal blood pressure value, the blood pressure measuring device 22 may determine a plurality of pressure values according to the PPG model parameter and the abnormal blood pressure value when performing calibration, and send the plurality of pressure values to the pressurizing device 21 one by one to notify the pressurizing device 21 to pressurize successively. The blood pressure measuring device 22 may respond to the confirmation operation of the user by sending a pressure value to the pressurizing device 21 to notify the pressurizing device 21 to perform one pressurizing, and after the blood pressure measuring device 22 obtains the blood pressure value and the PPG signal through measurement, continue to respond to the confirmation operation of the user by sending another pressure value to the pressurizing device 21 to notify the pressurizing device 21 to continue to perform the pressurizing. The pressurizing device 21 pressurizes the brachial artery of the user according to the inflation of the balloon notified to the pressurizing device 21 to the pressure value. Thus, the blood pressure of the wrist radial artery of the user can be lowered. The blood pressure measuring device 22 may acquire a blood pressure value and a PPG signal after the pressurization by the pressurization apparatus 21 is completed, and store the blood pressure value and the PPG signal. Thus, when the pressurizing device 21 is pressurized to a pressure value, the blood pressure measuring device 22 can obtain a set of blood pressure values and PPG signals through measurement. The pressurizing device 21 may also continue to inflate the airbag of the pressurizing device 21 in accordance with the notification. Thus, each time the pressurizing device 21 is pressurized to a corresponding pressure value, the blood pressure measuring device 22 can obtain a set of blood pressure values and PPG signals through measurement, and when all the pressure values are pressurized by the pressurizing device 21, the blood pressure measuring device 22 can obtain a plurality of sets of blood pressure values and PPG signals under different blood pressures. Subsequently, multiple sets of blood pressure values and PPG signals at different blood pressures may be used as multiple calibration data for updating the PPG model for measuring blood pressure, and the updated PPG model may be used for blood pressure measurement. Therefore, more groups of blood pressure values and PPG signals can be obtained, so that the PPG model can be generally used for a larger blood pressure measurement range, and the accuracy of blood pressure measurement in a state of large blood pressure fluctuation can be improved.
Fig. 3 is a schematic physical structure of a pressurizing device according to an embodiment of the application. The pressurizing device 30 may be a cuff device, a belt device, an upper arm type sphygmomanometer, a forearm type sphygmomanometer, a cuff sphygmomanometer, or the like having a function of pressurizing an arterial blood vessel region. The pressurizing device 30 may be the pressurizing device 21 in the embodiment described in fig. 2.
The pressurizing device 30 may include a fixing belt 31 and a device body 32. The fixing strap 31 may be fixedly connected with the device body 32. The securing strap 31 may be worn on the upper arm of the user such that the device body 32 surrounds and conforms to the brachial artery of the user's arm. In some embodiments, the securing strap 31 may be a first balloon. A securing strap 31 may be provided around the upper arm of the user for securing the pressurizing device 30 and applying pressure to the brachial artery of the user by being inflated. The device body 32 may include a processor 33, a memory 34, a first micropump 35, a communication interface 37, and a power source 38. It is to be understood that the structure shown in fig. 3 does not constitute a limitation of the pressurizing device 30, and that the pressurizing device 30 may include more or less components than shown, or may combine certain components, or split certain components, or may have a different arrangement of components.
The processor 33, the memory 34, the first micropump 35, the communication interface 37, and the power source 38 are fixedly connected to the fixing belt 31. In some embodiments, the processor 33, the memory 34, the first micropump 35, the communication interface 37, and the power source 38 may be secured in the strap 31. In some embodiments, the processor 33, the memory 34, the first micropump 35, the communication interface 37, and the power source 38 may be secured in a housing, which is fixedly connected to the securing strap 31.
The memory 34 may be used to store software programs and modules, and the processor 33 executes various functional applications and data processing of the pressurizing device 30 by executing the software programs and modules stored in the memory 34. The memory 34 may mainly include a storage program area and a storage data area, wherein the storage program area may store an operating system, an application program (such as a sound playing function, etc.) required for at least one function, etc.; the storage data area may store data created according to the use of the pressurizing device 30 (e.g., historical data of a user, historical data of different normal users collected before shipment of the pressurizing device 30), and the like. In addition, memory 34 may include high-speed random access memory, and may also include non-volatile memory, such as at least one magnetic disk storage device, flash memory device, or other volatile solid-state storage device.
The first micropump 35 may be configured to inflate the first balloon to a predetermined pressure value, such that the first balloon compresses the brachial artery of the user, exerting pressure on the brachial artery.
The communication interface 37 may include a standard wired interface, a wireless interface, etc. The communication interface 37 is used for the pressurizing device 30 to communicate with the blood pressure measuring apparatus. For example, the communication interface 37 may be used for the pressurization device 30 to receive a pressurization notification sent by the blood pressure measurement apparatus, and for the pressurization device 30 to send a pressurization completion signal to the blood pressure measurement apparatus, or the like.
The power source 38 is used to power the pressurizing device 30. In some embodiments, power supply 38 may be logically coupled to processor 33 via a power management system to perform functions such as managing charging, discharging, and power consumption via the power management system.
The processor 33 may be a central processing unit (Central Processing Unit, CPU), but may also be other general purpose processors, digital signal processors (Digital Signal Processor, DSP), application specific integrated circuits (Application Specific Integrated Circuit, ASIC), field programmable gate arrays (Field-Programmable Gate Array, FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, or the like. The processor 33 may be a microprocessor or the processor 33 may be any conventional processor or the like, the processor 33 being a control center of the pressurizing device 30, the various interfaces and lines being utilized to connect various portions of the entire pressurizing device 30.
The processor 33 may perform various functions of the blood pressure measuring device and process data by running or executing software programs and/or modules stored in the memory 34 and invoking data stored in the memory 34. For example, in an embodiment of the present application, the processor may be configured to receive a pressurization notification including a pressure value sent by the blood pressure measurement device, and control the first micropump 35 to inflate the first bladder to the pressure value according to the pressure value.
It is understood that the fixing band 31 may be used only for fixing the pressurizing device 30, and the apparatus body 32 may further include a first air bag, which may be embedded in a portion of the fixing band 31 for locally pressurizing the upper arm by inflation, which is not limited by the present application.
Fig. 4 is a schematic physical structure diagram of a blood pressure measurement device according to an embodiment of the application. The blood pressure measuring device 40 may be an electronic device having a blood pressure measuring function, such as a wristwatch, a smart wristwatch, a bracelet, or a smart bracelet. In the following, a smart watch will be described as an example. The blood pressure measuring device 40 may be the blood pressure measuring device 22 in the embodiment depicted in fig. 2.
The blood pressure measuring device 40 may include a PPG detection unit 41, an input unit 42, a second balloon 43, a second micropump 44, a pressure sensor 45, a controller 46, a memory 47, a display screen 48, a communication interface 49, a power supply 410, and the like. It will be appreciated that the configuration shown in fig. 4 is not limiting of the blood pressure measurement device 40, and that the blood pressure measurement device 40 may include more or fewer components than shown, or may be a combination of certain components, or may have certain components split, or may have a different arrangement of components.
The PPG detection unit 41 may be used to acquire Photoplethysmography (PPG) signals. The PPG detection unit 41 may include a photodetector and a light emitting diode, and a probe composed of the photodetector and the light emitting diode may be directly in contact with the skin, and the emitted light beam will be reflected, absorbed, and scattered in skin tissue and blood. The light emitting diode is configured to receive the light signal, and the photodetector is configured to convert the light signal into a PPG signal, thereby obtaining a PPG signal, and simultaneously convert the analog signal into a digital signal and send the digital signal to the controller 46.
The input unit 42 may be used to receive input numeric or character information and to generate key signals related to user settings and function control of the blood pressure measuring device 40. In particular, the input unit 42 may include a touch panel and other input devices. The touch panel, also referred to as a touch screen, may collect touch operations thereon or thereabout by a user (e.g., operations thereon or thereabout by a user using any suitable object or accessory such as a finger, stylus, etc.), and drive the corresponding connection device according to a predetermined program. Alternatively, the touch panel may include two parts, a touch detection device and a touch controller. The touch detection device detects the touch azimuth of a user, detects a signal brought by touch operation and transmits the signal to the touch controller; the touch controller receives touch information from the touch sensing device and converts it to touch point coordinates, which are then sent to the controller 46, and can receive commands from the controller 46 and execute them. In addition, the touch panel may be implemented in various types such as resistive, capacitive, infrared, and surface acoustic wave. Other input devices may include, but are not limited to, one or more of a keypad, function keys (e.g., volume control keys, switch keys, etc., confirm keys), etc.
The second balloon 43 is operable to be inflated against the wrist radial artery of the user to compress the wrist radial artery to a flattened condition by compression. The second balloon 43 may also be deflated after the end of the test. In some embodiments, the second bladder 43 may be used to locally compress the wrist while other parts of the wrist are not compressed by the second bladder.
The second micropump 44 may be configured to inflate the second bladder 43 such that the second bladder 43 compresses the wrist and radial artery of the user.
The pressure sensor 45 may be used to collect pressure signals within the second bladder 43 during inflation or deflation of the second bladder 43 by the second micropump 44. The pressure signal comprises a pulse oscillation wave signal, and the controller can separate the pulse oscillation wave signal from the pressure signal and obtain a blood pressure value according to the pulse oscillation wave signal.
The controller 46 may perform various functions of the blood pressure measurement device 40 and process the data by running or executing software programs and/or modules stored in the memory 47 and invoking data stored in the memory 47 to obtain multiple sets of blood pressure values and PPG signals at different blood pressures. For example, in an embodiment of the present application, the controller 46 may be configured to determine a plurality of pressure values according to the PPG model parameter and the abnormal blood pressure value if the user blood pressure value is the abnormal blood pressure value, and send the plurality of pressure values to the pressurizing device one by one. For another example, the controller 46 may be further configured to obtain a blood pressure value and a PPG signal after each pressurization of the pressurization device to a pressure value, and store the blood pressure value and the PPG signal.
The memory 47 may be used to store software programs and modules that are stored in the memory 47 for execution by the controller in performing various functional applications and data processing of the blood pressure measurement device 40. The memory 47 may mainly include a storage program area that may store an operating system, application programs required for at least one function (such as a sound playing function, an image playing function, etc.), and a storage data area; the stored data area may store data created from the use of the sphygmomanometer (e.g., conversion model, PPG model parameters, user's historical data, different normal user's historical data collected prior to shipment of the blood pressure measuring device 40), etc. In addition, memory 47 may include high-speed random access memory, and may also include non-volatile memory, such as at least one magnetic disk storage device, flash memory device, or other volatile solid-state storage device.
The display screen 48 may be used to display information entered by the user or provided to the user as well as various menus of the blood pressure measuring device 40. The display screen 48 may include a display panel, which may optionally be configured in the form of a liquid crystal display unit (Liquid Crystal Display, LCD), an Organic Light-Emitting Diode (OLED), or the like. Alternatively, the touch panel may overlay the display panel, and when the touch panel detects a touch operation thereon or thereabout, the touch panel is communicated to the controller 46 to determine the type of touch event, and the controller 46 then provides a corresponding visual output on the display panel based on the type of touch event.
Although in fig. 4 the touch panel and the display panel are two separate components to implement the input and output functions of the blood pressure measuring device 40, in some embodiments the touch panel and the display panel may be integrated to implement the input and output functions of the blood pressure measuring device 40.
The communication interface 49 may include a standard wired interface, a wireless interface, etc. The communication interface 49 is used for communication of the blood pressure measuring device 40 with the pressurizing apparatus. For example, the communication interface 49 may be used for the blood pressure measuring device 40 to send a pressurization notification to the pressurizing apparatus, to receive a pressurization completion signal sent by the pressurizing apparatus, and the like.
The power supply 410 is used to power the blood pressure measuring device 40. In some embodiments, the power supply 410 may be logically connected to the controller 46 through a power management system, so as to perform functions of managing charging, discharging, and power consumption management through the power management system.
Fig. 5 is a schematic diagram of another physical structure of the blood pressure measurement device according to the embodiment of the present application. The blood pressure measuring device 50 includes a watch body 51, a wristband 52, and a second air bag 43. The meter body 51 is provided with a PPG detection unit 41, a second micropump 44, a pressure sensor 45, a controller 46, a memory 47, a communication interface 49, and a power supply 410. The input unit 42 and the display screen 48 may be provided on the surface of the watch body 51. Wristband 52 includes a first wristband 521, a second wristband 522, and a wristband clasp 523. The first band 521 and the second band 522 are respectively connected to opposite sides of the watch body 51. The second airbag 43 is stacked on the first band 521 and is located inside the first band 521. When the blood pressure measuring device 50 is worn by the user, the second air bladder 43 is positioned on one side of the first wristband 521 and the wrist of the user, and is attached to the wrist artery of the wrist of the user. Clasp 523 connects first band 521 and second band 522. In some embodiments, the watch buckle 523 includes a first lock portion and a second lock portion. The first locking portion is connected to the first band 521. Second locking portion is coupled to second wristband 522. The first locking portion and the second locking portion are detachably locked to each other to wear the blood pressure measuring device 50 on the wrist of the user. In some embodiments, watchband clasp 523 can be a butterfly clasp. It is understood that the watchband buckle 523 can also be a clasp, a hidden buckle, a strap button, a folding safety buckle, a folding buckle, or a needle buckle, which is not limited in this regard.
It is understood that the second air bag 43 may further include a pressure sensor 45, and the pressure sensor 45 is disposed in the second air bag 43, so that the second air bag 43 may measure a blood pressure value during the inflation or deflation of the second air bag 43 by the second micropump 44, which is not limited in the present application.
For convenience of understanding, the following embodiments of the present application will take the pressurization device having the structure shown in fig. 3 and the blood pressure measurement device having the structure shown in fig. 4 to 5 as examples, and the method for calibrating blood pressure provided by the embodiments of the present application will be specifically described with reference to the accompanying drawings and application scenarios.
Referring to fig. 6, a flowchart of a blood pressure calibration method according to an embodiment of the application is shown. The blood pressure calibration method comprises the following steps:
s601: the blood pressure measuring device enters a calibration state.
In some embodiments, the blood pressure measurement device may enter a calibration state according to a calibration request initiated actively by a user. For example, the blood pressure measurement device may enter a calibration state in response to a first calibration operation acting on the blood pressure measurement device.
In some embodiments, the blood pressure measurement device may include a calibration key. The calibration key is used for triggering to enter a calibration state. For example, the user may press the calibration key for a long time, and the blood pressure measurement device may receive the long-time pressing operation of the user and enter the calibration state according to the long-time pressing operation of the user. It will be appreciated that other functions may be implemented by the calibration key, and the user may set the calibration key to have different functions by setting different operation times, operation numbers, etc., for example, the user may set an operation of pressing the "calibration key" for a short time to return to the home screen interface. At this time, the first calibration operation may be a long-press operation of the calibration key.
In some embodiments, the blood pressure measuring device may further be provided with a combination key. The combination key is used for triggering to enter a calibration state. For example, the user presses both the a key and the B key on the blood pressure measuring device, and the blood pressure measuring device may receive the user's operation of pressing the combination key and enter the calibration state according to the user's operation of pressing the combination key. At this time, the first calibration operation may be a pressing operation of the combination key.
In some embodiments, the display screen of the blood pressure measurement device may display a control, icon, or button for triggering a function to enter the calibration state, which the user may operate when the focus of the blood pressure measurement device is on. At this time, the first calibration operation may be an operation on a control, icon, or button on the display screen.
In some embodiments, the pressurizing device may transmit a blood pressure abnormality signal to the blood pressure measurement device based on the measured blood pressure value of the user, and the blood pressure measurement device may be calibrated based on the blood pressure abnormality signal prompt and enter a calibration state in response to a second calibration operation acting on the blood pressure measurement device based on the prompt. At this time, the second calibration operation may be a click operation of the confirm button in fig. 7.
Specifically, the user has worn the pressurizing device and the blood pressure measuring apparatus, and the pressurizing device has established a communication connection with the blood pressure measuring apparatus. The pressurizing device may measure the user's blood pressure value by activating the first micropump to inflate the first balloon.
In some embodiments, the pressurizing device transmits a blood pressure abnormality signal to the blood pressure measurement device when the measured blood pressure value of the user exceeds a first historical blood pressure value of the user by a preset threshold. The first historical blood pressure value of the user is all blood pressure values directly measured by the user by using the pressurizing equipment before the blood pressure is measured. It will be appreciated that the first historical blood pressure value of the user may also be a blood pressure value obtained by the pressurizing device via other blood pressure devices capable of communicating with the pressurizing device, as the application is not limited in this respect. The preset threshold may be a specific blood pressure value. The measured user blood pressure value exceeding the first historical blood pressure value of the user by a preset threshold may be at least one specific blood pressure value above the systolic blood pressure range in the first historical blood pressure value of the user or at least one specific blood pressure value above the diastolic blood pressure range in the first historical blood pressure value of the user. For example, if the systolic blood pressure range in the first historical blood pressure value of the user is 90-130 millimeters of mercury (mmHg), and the preset threshold is 10mmHg, then the measured blood pressure value of the user exceeding the preset threshold of the first historical blood pressure value of the user may be the measured systolic blood pressure value being higher than 140mmHg. Or for example, the range of the diastolic blood pressure in the first historical blood pressure value of the user is 60-89 mmHg, and the preset threshold value is 1mmHg, and the measured blood pressure value of the user exceeding the preset threshold value of the first historical blood pressure value of the user can be the measured diastolic blood pressure being higher than 90mmHg. The preset threshold may also be a percentage, and the measured user blood pressure value exceeding the first historical blood pressure value of the user preset threshold may be a percentage at least above the highest blood pressure value of the systolic blood pressure range in the first historical blood pressure value of the user, or a percentage at least above the highest blood pressure value of the diastolic blood pressure range in the first historical blood pressure value of the user. For example, if the systolic blood pressure range in the first historical blood pressure value of the user is 90mmHg to 130mmHg and the preset threshold is 10%, the measured systolic blood pressure value of the user exceeding the preset threshold of the first historical blood pressure value of the user may be that the measured systolic blood pressure is higher than 143mmHg. Or for example, the range of the diastolic blood pressure in the first historical blood pressure value of the user is 60-89 mmHg, and the preset threshold value is 10%, and the measured blood pressure value of the user exceeding the preset threshold value of the first historical blood pressure value of the user may be the measured diastolic blood pressure being higher than 97.9mmHg.
In some embodiments, the pressurizing device transmits a blood pressure abnormality signal to the blood pressure measurement device when the measured blood pressure value of the user exceeds a first pre-stored threshold value. The first pre-stored threshold values may include a systolic pressure range and a diastolic pressure range. The systolic blood pressure range may be, for example, 90 to 139mmHg. The diastolic pressure range may be, for example, 60 to 89mmHg. The pressurizing device generates the above-described blood pressure abnormality signal when the systolic pressure of the measured blood pressure value of the user is 140mmHg or more, or the diastolic pressure is 90mmHg or more. The first pre-stored threshold value may be a blood pressure value obtained by collecting blood pressure values of a plurality of normal users before the pressurization device leaves the factory. The first pre-stored threshold value may be measured directly by the pressurizing device, or may be a blood pressure value obtained by the pressurizing device through another blood pressure device capable of communicating with the pressurizing device.
The blood pressure measuring device displays a first calibration prompt interface 70 according to the blood pressure abnormality signal, as shown in fig. 7. The first calibration prompt interface 70 is used to prompt the user to perform calibration. In fig. 7, the first calibration prompt interface 70 includes a first prompt 71, a cancel button 73, and a confirm button 74. The first hint information 71 may be hint 1. Prompt 1 may be, for example, "do calibration? ". The first prompt 71 is used to prompt the user that calibration is to be performed. The cancel button 73 is used to trigger the blood pressure measuring device to cancel into the calibration state. The confirm button 74 is used to trigger the blood pressure measurement device into a calibrated state. It will be appreciated that fig. 7 is an example of a first calibration prompt interface 70, and the present application is not limited to the content and form of the first calibration prompt interface 70. At this time, the user may operate the confirm button 74, for example, the user clicks the confirm button 74, as shown in fig. 7. In response to the operation of clicking the confirm button 74, the blood pressure measurement device enters a calibration state.
It can be understood that the blood pressure measuring device can calibrate according to the prompt of the blood pressure value of the user measured by the pressurizing device, at this time, the blood pressure measuring device judges whether the blood pressure value is abnormal according to the received blood pressure value, and prompts to calibrate when the blood pressure value is abnormal, and the application is not limited to this.
In some embodiments, the blood pressure measurement device may be calibrated based on an abnormal blood pressure cue measured by the blood pressure measurement device via the pressure sensor, and enter a calibration state in response to a third calibration operation acting on the blood pressure measurement device based on the cue. At this time, the third calibration operation may be a click operation of the confirm button in fig. 8.
Specifically, the blood pressure measuring device may measure the user's blood pressure value by activating the second micropump to inflate the second bladder.
In some embodiments, the blood pressure measurement device displays a second calibration prompt interface 80 as shown in fig. 8 when the measured blood pressure value of the user exceeds a second historical blood pressure value of the user by a preset threshold. The second historical blood pressure value of the user is all blood pressure values obtained by the direct measurement of the user through the pressure sensor by utilizing the blood pressure measuring device before the blood pressure is measured. It is understood that the second historical blood pressure value of the user may also be a blood pressure value obtained by the blood pressure measuring device through other blood pressure devices capable of communicating with the blood pressure measuring device, which is not limited by the present application. The preset threshold may be a specific blood pressure value. The measured user blood pressure value exceeding the second historical blood pressure value of the user by a preset threshold value may be at least one specific blood pressure value above the systolic blood pressure range in the second historical blood pressure value of the user or at least one specific blood pressure value above the diastolic blood pressure range in the second historical blood pressure value of the user. For example, if the systolic blood pressure range in the second historical blood pressure value of the user is 85-135 millimeters of mercury (mmHg), and the preset threshold is 10mmHg, then the measured blood pressure value of the user exceeding the preset threshold for the second historical blood pressure value of the user may be the measured systolic pressure being higher than 145mmHg. Or for example, the diastolic blood pressure range in the second historical blood pressure value of the user is 60-85 mmHg, and the preset threshold value is 10mmHg, and the measured blood pressure value of the user exceeding the preset threshold value of the second historical blood pressure value of the user may be the measured diastolic blood pressure being higher than 95mmHg. The preset threshold may also be a percentage, and the measured user blood pressure value exceeding the second historical blood pressure value of the user preset threshold may be a percentage at least above the highest blood pressure value of the systolic blood pressure range in the second historical blood pressure value of the user, or a percentage at least above the highest blood pressure value of the diastolic blood pressure range in the second historical blood pressure value of the user. For example, if the systolic blood pressure range in the second historical blood pressure value of the user is 85-135 mmHg and the preset threshold is 10%, then the measured blood pressure value of the user exceeding the preset threshold of the second historical blood pressure value of the user may be that the measured systolic blood pressure is higher than 148.5 mmHg. Or for example, the diastolic blood pressure range in the second historical blood pressure value of the user is 60-85 mmHg, and the preset threshold value is 10%, and the measured diastolic blood pressure exceeding the preset threshold value of the second historical blood pressure value of the user may be 93.5 mmHg.
In some embodiments, the blood pressure measurement device displays a second calibration prompt interface 80 as shown in fig. 8 when the measured blood pressure value of the user exceeds a second pre-stored threshold value. The second pre-stored threshold value may be a blood pressure value obtained by collecting blood pressure values of a plurality of normal users before the blood pressure measuring device leaves the factory. The second pre-stored threshold value may be obtained by directly measuring the blood pressure by using the blood pressure measuring device through a pressure sensor, or may be a blood pressure value obtained by the blood pressure measuring device through other blood pressure equipment capable of communicating with the blood pressure measuring device. The second pre-stored threshold values may include a systolic pressure range and a diastolic pressure range. The systolic blood pressure range may be, for example, 90 to 140mmHg. The diastolic pressure range may be, for example, 60 to 89mmHg.
The second calibration prompting interface 80 is used to prompt the user to perform calibration. In fig. 8, the second calibration prompt interface 80 includes a second prompt 81, a cancel button 83, and a confirm button 84. The second hint information 81 may be hint 2. Hint 2 may be, for example, "ready to enter calibration state: please confirm whether the pressurizing device is worn, and establish a communication connection between the pressurizing device and the blood pressure measuring apparatus. The second prompting information 81 is used for prompting the user to wear the pressurizing device and establishing communication connection between the pressurizing device and the blood pressure measuring device. The cancel button 83 is used to trigger the blood pressure measuring device to cancel into the calibration state. The confirm button 84 is used to trigger the blood pressure measuring device into a calibrated state. It will be appreciated that FIG. 8 is an example of a second calibration prompt interface 80, and the application is not limited to the contents and form of the second calibration prompt interface 80. At this time, the user may operate the confirm button 84, for example, the user clicks the confirm button 84, as shown in fig. 8. In response to the operation of clicking the confirm button 84, the blood pressure measurement device enters a calibration state.
In some embodiments, the blood pressure measuring device may be calibrated according to an abnormal blood pressure cue measured by the blood pressure measuring device through the PPG detection unit, and enter a calibration state according to the cue in response to a third calibration operation acting on the blood pressure measuring device.
In particular, the blood pressure measuring device may measure the user blood pressure value by the PPG detection unit. In some embodiments, the blood pressure measurement device displays a second calibration prompt interface 80 as shown in fig. 8 when the measured blood pressure value of the user exceeds a third historical blood pressure value of the user by a preset threshold. The third historical blood pressure value of the user is all blood pressure values obtained by the direct measurement of the user through the PPG detection unit by utilizing the blood pressure measuring device before the blood pressure is measured. It is understood that the third historical blood pressure value of the user may also be a blood pressure value obtained by the blood pressure measuring device through other blood pressure devices capable of communicating with the blood pressure measuring device, which is not limited by the present application. The preset threshold may be a specific blood pressure value. The measured user blood pressure value exceeding the third historical blood pressure value of the user by a preset threshold may be at least one specific blood pressure value above the systolic blood pressure range in the third historical blood pressure value of the user or at least one specific blood pressure value above the diastolic blood pressure range in the third historical blood pressure value of the user. For example, if the systolic blood pressure range in the third historical blood pressure value of the user is 85-135 millimeters of mercury (mmHg), and the preset threshold is 6mmHg, then the measured blood pressure value of the user exceeding the preset threshold of the third historical blood pressure value of the user may be the measured systolic blood pressure value being higher than 141mmHg. Or for example, the range of the diastolic blood pressure in the third historical blood pressure value of the user is 60-85 mmHg, and the preset threshold value is 6mmHg, and the measured blood pressure value of the user exceeding the preset threshold value of the third historical blood pressure value of the user can be the measured diastolic blood pressure being higher than 91mmHg. The preset threshold may also be a percentage, and the measured user blood pressure value exceeding the third historical blood pressure value of the user preset threshold may be a percentage at least above the highest blood pressure value of the systolic blood pressure range in the third historical blood pressure value of the user, or a percentage at least above the highest blood pressure value of the diastolic blood pressure range in the third historical blood pressure value of the user. For example, if the systolic blood pressure range in the third historical blood pressure value of the user is 85-135 mmHg and the preset threshold is 6%, the measured systolic blood pressure value of the user exceeding the preset threshold of the third historical blood pressure value of the user may be that the measured systolic blood pressure is higher than 143.1mmHg. Or for example, the range of the diastolic blood pressure in the third historical blood pressure value of the user is 60-85 mmHg, and the preset threshold value is 6%, and the measured blood pressure value of the user exceeding the preset threshold value of the third historical blood pressure value of the user can be the measured diastolic blood pressure being higher than 90.1mmHg.
In some embodiments, the blood pressure measurement device generates a second calibration prompt interface 80 as shown in fig. 8 when the measured blood pressure value of the user exceeds a third pre-stored threshold value. The third pre-stored threshold value may be a blood pressure value obtained by collecting blood pressure values of a plurality of normal users before the blood pressure measuring device leaves the factory. The third pre-stored threshold value may be a blood pressure value obtained by directly measuring the blood pressure by the blood pressure measuring device through the PPG detecting unit, or may be a blood pressure value obtained by the blood pressure measuring device through other blood pressure devices capable of communicating with the blood pressure measuring device. The second pre-stored threshold values may include a systolic pressure range and a diastolic pressure range. The systolic blood pressure range may be, for example, 90 to 140mmHg. The diastolic pressure range may be, for example, 60 to 90mmHg.
S602: the blood pressure measuring device determines N different pressure values according to PPG model parameters and user blood pressure values, wherein N is more than or equal to 1.
In some embodiments, if the blood pressure measurement device is first used, the PPG model parameters are initial PPG model parameters. In some embodiments, if the blood pressure measurement device is used for a period of time, the PPG model parameters are updated PPG model parameters.
In some embodiments, if the step S601 is to perform calibration according to the measured abnormal blood pressure, the user blood pressure value may be the abnormal blood pressure value measured by the pressure device in the step S601, or the abnormal blood pressure value measured by the blood pressure measuring device in the step S601 by the pressure sensor, or the abnormal blood pressure value measured by the blood pressure measuring device in the step S601 by the PPG detection unit.
In some embodiments, if step S601 is the user actively initiating the calibration request, after step S601, the method further includes: the blood pressure measuring device or the pressurizing apparatus measures the blood pressure value of the user and judges whether the blood pressure value of the user is an abnormal blood pressure value. At this time, the blood pressure value of the user may be the blood pressure value of the user measured by the blood pressure measuring device or the pressurizing device after step S601, and the process of determining whether the blood pressure value of the user is the abnormal blood pressure value is the same as the process of determining whether the blood pressure value of the user is the abnormal blood pressure value by the pressurizing device and the blood pressure measuring device in step S601, which is not described herein. It will be appreciated that the pressurizing device may send the measured blood pressure value of the user directly to the blood pressure measuring device after the blood pressure value of the user is measured.
In some embodiments, the blood pressure measurement device may determine N different calibrated blood pressure values from PPG model parameters and abnormal blood pressure values, and determine N different pressure values from the N different calibrated blood pressure values. The calibrated blood pressure value is the blood pressure state required by the blood pressure measuring device.
In some embodiments, the blood pressure measurement device may determine a calibrated blood pressure range according to PPG model parameters and abnormal blood pressure values, and determine N different calibrated blood pressure values according to the calibrated blood pressure range. In some embodiments, the calibrated blood pressure range includes a blood pressure range [ a, b ] formed by a blood pressure range corresponding to the PPG model parameter and an abnormal blood pressure value, wherein if the abnormal blood pressure value is an abnormal blood pressure value of the systolic blood pressure, a is a maximum value of the systolic blood pressure range corresponding to the PPG model parameter, and b is a systolic blood pressure of the abnormal blood pressure value; if the abnormal blood pressure value is the abnormal blood pressure value of the diastolic blood pressure, a is the maximum value of the diastolic blood pressure range corresponding to the PPG model parameter, and b is the diastolic blood pressure of the abnormal blood pressure value. For example, if the PPG model parameter corresponds to a systolic blood pressure range of 110 to 130mmHg and the systolic blood pressure of an abnormal blood pressure value is 150mmHg, the calibrated blood pressure range is 130 to 150mmHg. Accordingly, the plurality of different calibrated blood pressure values may be 145mmHg,140mmHg,135mmHg and 130mmHg, respectively, as in fig. 9.
In some embodiments, each pressure value corresponds to a calibrated blood pressure value. In some embodiments, the blood pressure measurement device may determine pressure values corresponding to N different calibrated blood pressure values from a pre-trained conversion model stored in the blood pressure measurement device. The input of the conversion model is a calibrated blood pressure value, and the output of the conversion model is a pressure value. Wherein the greater the pressure value, the smaller the corresponding calibrated blood pressure value. For example, the calibrated blood pressure values 145mmHg,140mmHg,135mmHg, and 130mmHg in FIG. 9 correspond to pressure values of 8mmHg,15mmHg,23mmHg, and 30mmHg, respectively.
S603: the blood pressure measurement device receives the current confirmation operation and generates a current pressurization notification according to the current confirmation operation, the current pressurization notification including the current pressure value.
In some embodiments, the current pressure value is one of a plurality of pressure values. The plurality of pressure values are included in the current pressurization notification formed at different times one by one in order from small to large. That is, each time the blood pressure measuring device receives the current confirmation operation acting on the blood pressure measuring device, a current pressurization notification including a current pressure value is generated, and the current pressure value in the current pressurization notifications generated a plurality of times is selected from small to large. For example, the current pressure value in the current pressurization notification generated for the first time is 8mmHg, the current pressure value in the current pressurization notification generated for the second time is 15mmHg, the current pressure value in the current pressurization notification generated for the third time is 23mmHg, and the current pressure value in the current pressurization notification generated for the fourth time is 30mmHg. Therefore, the pressure values can be sent to the pressurizing device one by one according to the current confirmation operation received by the pressurizing device from small to large in sequence, so that the pressurizing device can gradually pressurize according to the pressure values received by the pressurizing device from small to large in sequence, the pressurizing device can continuously pressurize without performing air release operation in the middle during the gradual pressurizing, and accordingly, the blood pressure value at the wrist of the user can be adjusted to be close to a plurality of different calibration blood pressure values from the blood pressure value before the pressurizing device does not pressurize.
In some embodiments, the blood pressure measurement device may display a pressurization prompt interface for the user to confirm whether to notify the pressurization device of pressurization. The blood pressure measurement device may receive user operation of the pressurization prompt interface to generate a current pressurization notification. For example, the pressurization prompt interface includes a confirmation pressurization button and a cancel pressurization button. The cancel pressurization button is used for triggering the blood pressure measuring device to cancel the notification pressurization device for pressurization. The confirm pressurization button is used for triggering the blood pressure measuring device to inform the pressurization equipment of pressurization. The application is not limited to the contents and form of the pressurization prompt interface. At this time, the user may operate the confirmation pressurization button, for example, the user clicks the confirmation pressurization button, and the blood pressure measurement device may generate the current pressurization notification in response to the operation of clicking the confirmation pressurization button. Then, the current confirmation operation is a click operation of the confirmation pressurization button in the pressurization prompt interface. It can be understood that the current confirmation operation of the user on the blood pressure measurement device may also be one key or a plurality of keys for operating the blood pressure measurement device, and the blood pressure measurement device may generate a prompt interface to prompt the user to press the one key or the plurality of keys to notify the pressurizing device of pressurization, so that the current confirmation operation is a pressing operation of the one key or the plurality of keys at this time, which is not limited in the present application.
S604: the blood pressure measuring device sends a current pressurization notification to the pressurization device.
In some embodiments, the blood pressure measurement device sends a current pressurization notification to the pressurization device to inform the pressurization device to pressurize according to the current pressure value in the current pressurization notification. Thus, the pressurizing device can start pressurizing after receiving the current pressurizing notification.
S605: the pressurizing device controls the first micropump to inflate the first bladder to a current pressure value according to the current pressurization notification.
In some embodiments, the pressurizing device controls the first micropump to inflate the first balloon to a current pressure value to effect the application of pressure to the brachial artery. At this time, the first balloon may press the brachial artery vessel of the user. The blood pressure of the radial artery of the wrist downstream of the brachial artery can be adjusted accordingly. Continuing with the above description with reference to fig. 9, before the pressurizing device does not pressurize, the current blood pressure value at the wrist of the user is 150mmHg, and if the pressurizing device inflates the first balloon to the current pressure value of 8mmHg and the calibrated blood pressure value corresponding to the current pressure value of 8mmHg is 145mmHg, the blood pressure of the radial artery of the wrist of the downstream branch of the brachial artery of the arm can be adjusted from 150mmHg to 145mmHg, for example, the blood pressure of the radial artery of the wrist is adjusted to 146mmHg.
S606: the pressurization device transmits a current pressurization completion signal to the blood pressure measurement device after the pressurization of the current time is completed.
In some embodiments, the pressurization device sends a current pressurization completion signal to the blood pressure measurement device, which may inform the blood pressure measurement device that the pressurization device has completed the current pressurization. Thus, the blood pressure measuring device may start measuring the biological signal of the user after receiving the current pressurization completion signal.
S607: the blood pressure measuring device obtains a pulse oscillation wave signal of the user according to the current pressurization completion signal.
In some embodiments, the blood pressure measurement device controls the second micropump to inflate and deflate the second bladder in response to the current pressurization complete signal. The blood pressure measuring device can control the second micropump to inflate and pressurize the second air bag to block arterial blood flow in the wrist radial artery blood vessel, and then slowly deflate and decompress. The air pressure of the second air bag is reduced to a certain degree, the blood flow can pass through the blood vessel, and a certain oscillation wave exists, the oscillation wave propagates to the pressure sensor, the blood pressure measuring device can collect the pressure signal of the second air bag in real time through the pressure sensor, and the pulse oscillation wave signal shown in fig. 10A is determined according to the collected pressure signal. Thus, when the blood pressure value at the wrist of the user is adjusted to be in the vicinity of the calibration blood pressure value, for example, 145mmHg or so as shown in fig. 9, a pulse oscillation wave signal which is more accurate for the user can be measured.
S608: the blood pressure measuring device determines a blood pressure value from the pulse oscillation wave signal.
In some embodiments, the blood pressure measuring device may process the pulse oscillation wave signal to obtain a feature set related to blood pressure in the pulse oscillation wave signal, and determine a blood pressure value according to the feature set. Each pulse wave signal corresponds to a set of characteristic data related to blood pressure, namely a characteristic set related to blood pressure. For example, the characteristic data of the pulse wave signal may be at least one of a maximum value of an amplitude envelope of the pulse wave signal, a first inflection point, a second inflection point, and the like. Thus, the blood pressure measuring device can determine the current blood pressure value at the wrist of the user, such as 146mmHg, according to the more accurate pulse oscillation wave signal. It can be understood that the current blood pressure value at the wrist of the user is a more accurate blood pressure value due to the fact that the pulse wave signal is more accurate.
S609: the blood pressure measuring device collects PPG signals of a user through a PPG detection unit.
In some embodiments, after the second micro pump inflates and deflates the second air bladder, the blood pressure measurement device may collect PPG signals of the user for a period of time (e.g. 1-2 minutes, etc.) by the PPG measurement unit, to obtain PPG signals of the user as shown in fig. 10B. Thus, when the blood pressure value at the wrist of the user is adjusted to be in the vicinity of the calibration blood pressure value, for example, 145mmHg or so as shown in fig. 9, the PPG signal of the user can be obtained.
S610: the blood pressure measurement device stores a blood pressure value and a PPG signal.
In some embodiments, the blood pressure measurement device may store the blood pressure value and the PPG signal to a memory of the blood pressure measurement device.
In some embodiments, the time of acquiring the pulse wave signal of the user and the time of acquiring the PPG signal of the user may be the same, or the temporal distance may be less than a preset threshold. For example, the PPG signal of the user is acquired immediately after the pulse oscillation wave signal of the user is acquired. The change of the physical state or the blood pressure state at the wrist of the user at the moment of acquiring the pulse oscillating wave signal of the user and the moment of acquiring the PPG signal of the user is smaller, so that the pulse oscillating wave signal of the user and the PPG signal of the user have a certain correlation, and the blood pressure value obtained according to the pulse oscillating wave signal of the user and the PPG signal have a certain correlation. The stored blood pressure values and PPG signals may be used as a set of blood pressure values and PPG signals. Thus, a set of blood pressure values and PPG signals may be obtained when the current blood pressure value at the wrist of the user is adjusted to be around the calibrated blood pressure value, for example, a set of blood pressure values and PPG signals at around 145mmHg as shown in fig. 9. The stored set of blood pressure values and PPG signals may subsequently be used as a set of calibration data for updating the PPG model of the blood pressure measurement device when subsequently measuring blood pressure.
S611: the blood pressure measuring device judges whether the number of times of pressurization of the pressurizing device reaches a first preset value, wherein the first preset value is equal to the number of all the pressure values.
In some embodiments, the blood pressure measurement device determines whether the number of pressurization times of the pressurization device reaches a first preset value based on the number of times the current pressurization notification is sent. If the number of times of sending the current pressurization notification is equal to the number of all the pressure values, the number of times of pressurization of the pressurization device reaches a first preset value. If the number of times of sending the current pressurization notification is not equal to the number of all the pressure values, the number of times of pressurization by the pressurization device does not reach the first preset value.
In some embodiments, the blood pressure measuring device determines whether the number of pressurization times of the pressurization device reaches a first preset value according to the blood pressure value and the number of sets of PPG signals. If the number of sets of blood pressure values and PPG signals is equal to the number of all pressure values, the number of pressurization times of the pressurization device reaches a first preset value. If the number of sets of blood pressure values and PPG signals is not equal to the number of all pressure values, the number of pressurization of the pressurization device does not reach the first preset value.
In some embodiments, if the number of times of pressurization of the pressurization device does not reach the first preset value, step S603 is performed. In some embodiments, if the number of times of pressurization of the pressurization device reaches the first preset value, step S612 is performed.
S612: the blood pressure measuring device updates a PPG model of the blood pressure measuring device according to all sets of blood pressure values and PPG signals.
In some embodiments, the blood pressure measurement device may process each set of blood pressure values and the PPG signal in the PPG signal to obtain a set of blood pressure related features in the PPG signal and store the set of features. Wherein, each PPG signal corresponds to a set of blood pressure related feature data, i.e. a blood pressure related feature set. For example, the characteristic data of the PPG signal may be at least one of a main wave amplitude of the PPG signal, a microblog wave amplitude of the PPG signal, a main wave to microblog wave time interval of the PPG signal, a ratio of the main wave amplitude of the PPG signal to the microblog wave amplitude, a change ratio of a pulse wave area of the PPG signal, and the like. Then, the blood pressure measuring device can obtain one or more groups of blood pressure values and characteristic sets.
In some embodiments, the blood pressure measurement device may update the PPG model of the blood pressure measurement device based on all sets of blood pressure values and feature sets.
S613: the blood pressure measuring device measures blood pressure according to the updated PPG model.
It is understood that step S612 and step S613 may be omitted, and if the number of times of pressurization of the pressurization device reaches the first preset value, the process is ended, which is not limited by the present application.
It is understood that the order of steps S607-S608 and S609 may be interchanged, for example, the blood pressure measurement firstly collects the PPG signal of the user through the PPG detection unit according to the current pressurization completion signal, then obtains the pulse oscillation wave signal of the user, and determines the blood pressure value according to the pulse oscillation wave signal, which is not limited in the present application.
It may be understood that the first preset value in step S611 is N times the number of all the pressure values, N is any positive integer, and before step S612, the blood pressure measurement device further determines whether the number of pressurizing wheels of the pressurizing device reaches the second preset value N, where the number of pressurizing times of each wheel is equal to the number of all the pressure values, and the blood pressure measurement device and the pressurizing device may perform N-wheel calibration data acquisition, that is, the pressurizing device performs N-wheel from small to large pressurization, and the blood pressure measurement device performs N-wheel calibration data acquisition, where the number of calibration data acquired by each wheel of the blood pressure measurement device is the number of all the pressure values.
It is understood that in step S603, the plurality of pressure values may also be included in the current pressing notification formed different times one by one in order from large to small, that is, the current pressure value in the current pressing notification generated multiple times is selected from large to small, so that the plurality of pressure values may be sent to the pressing apparatus one by one in order from large to small according to the current confirmation operations received different times, and the pressing apparatus may press in order from large to small. Specifically, the pressurizing device may perform inflation pressurization according to the maximum current pressure value, and may gradually deflate and decompress according to other current pressure values from large to small, which is not limited in the present application.
It is understood that a plurality of pressure values may also be sent to the pressurizing device at a time, specifically, in step S603, if the blood pressure measuring device receives the current confirmation operation for the first time, the generated current pressurizing notification includes N pressure values; if the blood pressure measurement device does not receive the current confirmation operation for the first time, the generated current pressurization notification does not include a pressure value, and the pressurization device can pressurize in order from the pressure value to the pressure value, or in order from the pressure value to the pressure value, which is not limited in the application.
It will be appreciated that the present application is not limited in this respect, as it may be used to increase the blood pressure measurement range not only for systolic blood pressure but also for diastolic blood pressure.
Referring to fig. 11A and 11B, fig. 11A is a schematic diagram of a blood pressure value and a real blood pressure value measured after calibration by the conventional calibration method, and fig. 11B is a schematic diagram of a blood pressure value and a real blood pressure value measured after calibration by the blood pressure calibration method of the present application. Fig. 11A and 11B each record a change curve of the measured blood pressure versus the actual blood pressure. The blood pressure values measured in fig. 11A and 11B are indicated by broken lines, and the actual blood pressure values in fig. 11A and 11B are indicated by solid lines. From the curves of fig. 11A and 11B, it can be seen that the measured blood pressure value is closer to the true blood pressure value after calibration by the blood pressure calibration method of the present application than after calibration by the existing calibration method.
Fig. 12 is a schematic diagram of another blood pressure calibration system according to an embodiment of the application. The blood pressure calibration system 120 includes a blood pressure measurement device 1201 and a pressurizing apparatus 1202. The blood pressure measuring device 1201 is communicatively connected to the pressurizing apparatus 1202. The blood pressure measuring device 1201 is configured to be worn on a first part of a human body. The pressurizing device 1202 is for wearing on a second part of the human body. The second portion is different from the first portion. The blood pressure measurement device 1201 pre-stores current PPG model parameters. The blood pressure measuring device 1201 is used to obtain a blood pressure value of a user. If the user blood pressure value is an abnormal blood pressure value, the blood pressure measurement device 1201 is further configured to determine one or more pressure values according to the PPG model parameter and the abnormal blood pressure value, where the one or more pressure values include a first pressure value. The blood pressure measurement device 1201 is also configured to send a first pressurization notification to the pressurization device 1202, the first pressurization notification including a first pressure value. In response to the first pressurization notification, the pressurization device 1202 is configured to perform pressurization according to the first pressure value, and to send a first pressurization completion signal to the blood pressure measurement device 1201 after the pressurization is completed. In response to the first pressurization complete signal, the blood pressure measurement device 1201 is also used to measure a first blood pressure value and to acquire a first PPG signal. The blood pressure measurement device 1201 is also configured to store a first blood pressure value and a first PPG signal.
In some embodiments, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value. After the blood pressure measurement device 1201 has finished measuring the first blood pressure value and acquiring the first PPG signal, the blood pressure measurement device 1201 is further configured to send a second pressurization notification to the pressurization device 1202, the second pressurization notification comprising the second pressure value. In response to the second pressurization notification, the pressurization device 1202 is configured to perform pressurization according to the second pressure value, and to send a second pressurization completion signal to the blood pressure measurement device 1201 after the pressurization is completed. In response to the second pressurization complete signal, the blood pressure measurement device 1201 is also used to measure a second blood pressure value and to acquire a second PPG signal. The blood pressure measurement device 1201 is also configured to store a second blood pressure value and a second PPG signal.
In some embodiments, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value; the first pressurization notification includes a first pressure value and a second pressure value. After the blood pressure measuring device 1201 has finished measuring the first blood pressure value and acquiring the first PPG signal, the blood pressure measuring device 1201 is further configured to send a second pressurization notification to the pressurization device 1202. In response to the second pressurization notification, the pressurization device 1202 is configured to perform pressurization according to the second pressure value, and to send a second pressurization completion signal to the blood pressure measurement device 1201 after the pressurization is completed. In response to the second pressurization complete signal, the blood pressure measurement device 1201 is also used to measure a second blood pressure value and to acquire a second PPG signal. The blood pressure measurement device 1201 is also configured to store a second blood pressure value and a second PPG signal.
In some embodiments, the user blood pressure value is obtained for the blood pressure measuring device 1201 from the pressurizing device 1202, or is obtained for the blood pressure measuring device 1201 by PPG detection unit measurement of the blood pressure measuring device 1201, or is obtained for the blood pressure measuring device 1201 by micropump and balloon measurement of the blood pressure measuring device 1201.
In some embodiments, the blood pressure measurement device 1201 is further configured to update the PPG model based on all stored blood pressure values and the PPG signal. The blood pressure measuring device 1201 is also used to measure the blood pressure of the user according to the updated PPG model.
In some embodiments, the first location is a wrist and the second location is an upper arm.
In some embodiments, blood pressure measurement device 1201 includes a micropump, a balloon, and a PPG sensor. The blood pressure measuring device 1201 is also configured to control the micropump to inflate the bladder in response to the first pressurization complete signal to measure a first blood pressure value. The blood pressure measurement device 1201 is also configured to acquire a first PPG signal via the PPG sensor after the balloon deflation is completed.
In some embodiments, after the blood pressure measurement device determines one or more pressure values according to PPG model parameters and abnormal blood pressure values, the blood pressure measurement device 1201 is further configured to display a first pressurization prompting interface for prompting to start pressurization. The blood pressure measurement device 1201 is also configured to receive a first confirmation operation by the user. In response to a first confirmation operation by the user, the blood pressure measurement device 1201 is also configured to send a first pressurization notification to the pressurization apparatus 1202; the first pressurization notification is for notifying the pressurization device 1202 to perform pressurization according to the first pressure value.
In some embodiments, the blood pressure measurement device 1201 is further configured to determine one or more calibrated blood pressure values from PPG model parameters and abnormal blood pressure values; the blood pressure measurement device 1201 is further configured to determine one or more pressure values based on one or more calibrated blood pressure values, one for each calibrated blood pressure value.
Referring to fig. 13, a flowchart of another blood pressure calibration method according to an embodiment of the application is shown. The blood pressure calibration method is applied to a blood pressure measuring device. The blood pressure measuring device is used for being worn on a first part of a human body. The blood pressure measuring device is used for being in communication connection with the pressurizing device, and the pressurizing device is used for being worn on a second part of a human body. The second portion is different from the first portion. The blood pressure calibration method comprises the following steps:
s1301: and acquiring a blood pressure value of the user.
S1302: if the user blood pressure value is an abnormal blood pressure value, determining one or more pressure values according to the prestored PPG model parameter and the abnormal blood pressure value, wherein the one or more pressure values comprise a first pressure value.
S1303: transmitting a first pressurization notification to the pressurization device, the first pressurization notification including a first pressure value; the first pressurization notification is for notifying the pressurization device to perform pressurization according to the first pressure value.
S1304: a first pressurization completion signal sent by the pressurization device is received, the first pressurization completion signal being used to inform the blood pressure measurement device that the pressurization device has completed pressurization according to the first pressure value.
S1305: in response to the first pressurization complete signal, a first blood pressure value is measured and a first PPG signal is acquired.
S1306: the first blood pressure value and the first PPG signal are stored.
In some embodiments, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value, the method further comprising: after ending measuring the first blood pressure value and acquiring the first PPG signal, sending a second pressurization notification to the pressurization device, the second pressurization notification comprising a second pressure value; the second pressurization notification is used for notifying the pressurization device to pressurize according to the second pressure value; receiving a second pressurization completion signal sent by the pressurization device, the second pressurization completion signal being used for informing the blood pressure measurement device that the pressurization device has completed pressurization according to the second pressure value; measuring a second blood pressure value and acquiring a second PPG signal in response to the second pressurization complete signal; the second blood pressure value and the second PPG signal are stored.
In some embodiments, the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value, the first pressurization notification comprising the first pressure value and the second pressure value, the method further comprising: after the measurement of the first blood pressure value and the acquisition of the first PPG signal are finished, a second pressurization notification is sent to the pressurization equipment; the second pressurization notification is used for notifying the pressurization device to pressurize according to the second pressure value; receiving a second pressurization completion signal sent by the pressurization device, the second pressurization completion signal being used for informing the blood pressure measurement device that the pressurization device has completed pressurization according to the second pressure value; measuring a second blood pressure value and acquiring a second PPG signal in response to the second pressurization complete signal; the second blood pressure value and the second PPG signal are stored.
In some embodiments, obtaining the user blood pressure value comprises: acquiring a user blood pressure value from the pressurizing device; or the user blood pressure value is obtained through measurement of a PPG detection unit of the blood pressure measuring device; or the blood pressure value of the user is obtained through the micropump and the balloon measurement of the blood pressure measuring device.
In some embodiments, the method further comprises: updating the PPG model according to all stored blood pressure values and PPG signals; the blood pressure of the user is measured according to the updated PPG model.
In some embodiments, the first location is a wrist and the second location is an upper arm.
In some embodiments, measuring the first blood pressure value and acquiring the first PPG signal in response to the first pressurization complete signal comprises: responding to the first pressurization completion signal, and controlling a micropump of the blood pressure measuring device to inflate an air bag of the blood pressure measuring device to measure a first blood pressure value; after the balloon is deflated, a first PPG signal is acquired by a PPG sensor of the blood pressure measuring device.
In some embodiments, sending the first pressurization notification to the pressurization device includes: displaying a first pressurizing prompt interface, wherein the first pressurizing prompt interface is used for prompting the start of pressurizing; receiving a first confirmation operation of a user; in response to a first confirmation operation by the user, a first pressurization notification is sent to the pressurization device.
In some embodiments, determining one or more pressure values from pre-stored PPG model parameters and user blood pressure values comprises: determining one or more calibrated blood pressure values according to the PPG model parameters and the abnormal blood pressure values; one or more pressure values are determined from one or more calibrated blood pressure values, one for each calibrated blood pressure value.
In addition to the above methods and apparatus, embodiments of the present application provide a computer storage medium comprising computer instructions that, when executed on a blood pressure measurement device, cause the blood pressure measurement device to perform the method shown in fig. 13.
A computer program product comprising a program code which, when executed by a processor in a blood pressure measuring device, implements the method shown in fig. 13.
According to the application, if the user blood pressure value is an abnormal blood pressure value, the blood pressure measuring device determines one or more different pressure values according to the PPG model parameters and the abnormal blood pressure value, and sends a pressurizing notification to the pressurizing device, the pressurizing device applies different pressure values to adjust the blood pressure of the radial artery of the user to different blood pressures according to each pressurizing notification in the brachial artery vascular region of the user, and sends a pressurizing completion signal to the blood pressure measuring device after the pressurizing is completed, and the blood pressure measuring device measures and stores the blood pressure values and PPG signals under different blood pressures to obtain different groups of blood pressure values and PPG signals, so that data which are not in the PPG model can be obtained, and therefore, the pressurizing device begins to pressurize after receiving the pressurizing notification of the blood pressure measuring device, and the blood pressure measuring device begins to measure after receiving the pressurizing completion signal sent by the pressurizing device, thereby ensuring the accuracy of the measuring and ensuring the high accuracy of the blood pressure and the PPG signals; the stored blood pressure value and the PPG signal can lead the PPG model to be used in a larger blood pressure measurement range, can improve the accuracy of blood pressure measurement in a state of large blood pressure fluctuation, and can supplement data which are not in the PPG model for the blood pressure condition of a user due to consideration of the abnormal blood pressure value of the user, thereby further improving the accuracy of blood pressure measurement when the blood pressure of the user is measured subsequently.
From the above description of the embodiments, it will be apparent to those skilled in the art that the present application may be implemented by means of software plus necessary general purpose hardware, or of course by means of special purpose hardware including application specific integrated circuits, special purpose CPUs, special purpose memories, special purpose components, etc. Generally, functions performed by computer programs can be easily implemented by corresponding hardware, and specific hardware structures for implementing the same functions can be varied, such as analog circuits, digital circuits, or dedicated circuits. However, a software program implementation is a preferred embodiment for many more of the cases of the present application. Based on such understanding, the technical solution of the present application may be embodied essentially or in a part contributing to the prior art in the form of a software product stored in a readable storage medium, such as a floppy disk, a usb disk, a removable hard disk, a ROM, a RAM, a magnetic disk or an optical disk of a computer, etc., including several instructions for causing a computer device (which may be a personal computer, a server, or a network device, etc.) to execute the method according to the embodiments of the present application.
In the above embodiments, it may be implemented in whole or in part by software, hardware, firmware, or any combination thereof. When implemented in software, may be implemented in whole or in part in the form of a computer program product.
The computer program product includes one or more computer instructions. When loaded and executed on a computer, produces a flow or function in accordance with embodiments of the present application, in whole or in part. The computer may be a general purpose computer, a special purpose computer, a computer network, or other programmable apparatus. The computer instructions may be stored in a computer-readable storage medium or transmitted from one computer-readable storage medium to another computer-readable storage medium, for example, the computer instructions may be transmitted from one website, computer, server, or data center to another website, computer, server, or data center by a wired (e.g., coaxial cable, fiber optic, digital Subscriber Line (DSL)) or wireless (e.g., infrared, wireless, microwave, etc.). The computer readable storage medium may be any available medium that can be stored by a computer or a data storage device such as a server, data center, etc. that contains an integration of one or more available media. The usable medium may be a magnetic medium (e.g., a floppy Disk, a hard Disk, a magnetic tape), an optical medium (e.g., a DVD), or a semiconductor medium (e.g., a Solid State Disk (SSD)), or the like.
Finally, it should be noted that the above-mentioned embodiments are merely for illustrating the technical solution of the present application and not for limiting the same, and although the present application has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications and equivalents may be made to the technical solution of the present application without departing from the spirit and scope of the technical solution of the present application.

Claims (21)

1. The utility model provides a blood pressure calibration system, its characterized in that, blood pressure calibration system includes blood pressure measuring device and pressurization equipment, blood pressure measuring device with pressurization equipment communication connection, blood pressure measuring device is used for wearing in the first position of human body, pressurization equipment is used for wearing in the second position of human body, the second position is different with first position, blood pressure measuring device prestores PPG model parameter, wherein:
the blood pressure measuring device is used for acquiring a blood pressure value of a user;
if the user blood pressure value is an abnormal blood pressure value, the blood pressure measurement device is further configured to determine one or more pressure values according to the PPG model parameter and the abnormal blood pressure value, where the one or more pressure values include a first pressure value;
the blood pressure measurement device is further configured to send a first pressurization notification to the pressurization device, the first pressurization notification including the first pressure value;
In response to the first pressurization notification, the pressurization device is configured to perform pressurization according to the first pressure value, and send a first pressurization completion signal to the blood pressure measurement device after the pressurization is completed;
in response to the first pressurization complete signal, the blood pressure measurement device is further configured to measure a first blood pressure value and acquire a first PPG signal;
the blood pressure measurement device is further configured to store the first blood pressure value and the first PPG signal.
2. The blood pressure calibration system of claim 1, wherein:
the one or more pressure values further include a second pressure value, the second pressure value being greater than the first pressure value;
after the blood pressure measuring device finishes measuring the first blood pressure value and acquiring the first PPG signal,
the blood pressure measurement device is further configured to send a second pressurization notification to the pressurization device, the second pressurization notification including the second pressure value;
in response to the second pressurization notification, the pressurization device is configured to perform pressurization according to the second pressure value, and send a second pressurization completion signal to the blood pressure measurement device after the pressurization is completed;
in response to the second pressurization completion signal, the blood pressure measurement device is further configured to measure a second blood pressure value and acquire a second PPG signal;
The blood pressure measurement device is further configured to store the second blood pressure value and the second PPG signal.
3. The blood pressure calibration system of claim 1, wherein:
the one or more pressure values further include a second pressure value, the second pressure value being greater than the first pressure value;
the first pressurization notification includes the first pressure value and the second pressure value;
after the blood pressure measuring device finishes measuring the first blood pressure value and acquiring the first PPG signal,
the blood pressure measurement device is further configured to send a second pressurization notification to the pressurization device;
in response to the second pressurization notification, the pressurization device is configured to perform pressurization according to the second pressure value, and send a second pressurization completion signal to the blood pressure measurement device after the pressurization is completed;
in response to the second pressurization completion signal, the blood pressure measurement device is further configured to measure a second blood pressure value and acquire a second PPG signal;
the blood pressure measurement device is further configured to store the second blood pressure value and the second PPG signal.
4. A blood pressure calibration system according to any one of claims 1-3, wherein:
the user blood pressure value is obtained by the blood pressure measuring device from the pressurizing equipment, or is obtained by the blood pressure measuring device through the PPG detection unit of the blood pressure measuring device, or is obtained by the blood pressure measuring device through the micropump and the balloon of the blood pressure measuring device.
5. The blood pressure calibration system of any one of claims 1-4, wherein:
the blood pressure measuring device is also used for updating a PPG model according to all stored blood pressure values and PPG signals;
the blood pressure measuring device is also used for measuring the blood pressure of the user according to the updated PPG model.
6. The blood pressure calibration system of any one of claims 1-5, wherein:
the first part is a wrist and the second part is an upper arm.
7. The blood pressure calibration system of any one of claims 1-6, wherein:
the blood pressure measuring device comprises a micropump, a balloon and a PPG sensor;
in response to the first pressurization completion signal, the blood pressure measurement device is further configured to control the micropump to inflate the bladder to measure the first blood pressure value;
the blood pressure measurement device is further configured to acquire the first PPG signal via the PPG sensor after the balloon deflation is completed.
8. The blood pressure calibration system of any one of claims 1-7, wherein after the blood pressure measurement device determines one or more pressure values from the PPG model parameters and the abnormal blood pressure values:
the blood pressure measuring device is also used for displaying a first pressurization prompting interface, and the first pressurization prompting interface is used for prompting the start of pressurization;
The blood pressure measuring device is also used for receiving a first confirmation operation of a user;
in response to a first confirmation operation by the user, the blood pressure measurement device is further configured to send the first pressurization notification to the pressurization device; the first pressurization notification is for notifying the pressurization device to pressurize according to the first pressure value.
9. The blood pressure calibration system of any one of claims 1-8, wherein:
the blood pressure measuring device is also used for determining one or more calibration blood pressure values according to the PPG model parameters and the abnormal blood pressure values;
the blood pressure measuring device is further used for determining one or more pressure values according to one or more calibration blood pressure values, and each calibration blood pressure value corresponds to one pressure value.
10. A blood pressure calibration method applied to a blood pressure measurement device for wearing on a first part of a human body, the blood pressure measurement device being adapted to be in communication with a pressurizing device, the pressurizing device being adapted to be worn on a second part of the human body, the second part being different from the first part, the method comprising:
acquiring a blood pressure value of a user;
if the user blood pressure value is an abnormal blood pressure value, determining one or more pressure values according to a prestored PPG model parameter and the abnormal blood pressure value, wherein the one or more pressure values comprise a first pressure value;
Transmitting a first pressurization notification to the pressurization device, the first pressurization notification including the first pressure value; the first pressurization notification is used for notifying the pressurization device to pressurize according to the first pressure value;
receiving a first pressurization completion signal sent by the pressurization device, the first pressurization completion signal being used for informing the blood pressure measurement device that the pressurization device has completed pressurization according to the first pressure value;
measuring a first blood pressure value and acquiring a first PPG signal in response to the first pressurization complete signal;
the first blood pressure value and the first PPG signal are stored.
11. The blood pressure calibration method of claim 10, wherein the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value, the method further comprising:
after ending measuring the first blood pressure value and acquiring the first PPG signal, sending a second pressurization notification to the pressurization device, the second pressurization notification comprising the second pressure value; the second pressurization notification is used for notifying the pressurization device to pressurize according to the second pressure value;
receiving a second pressurization completion signal sent by the pressurization device, the second pressurization completion signal being used to inform the blood pressure measurement apparatus that the pressurization device has completed pressurization according to the second pressure value;
Measuring a second blood pressure value and acquiring a second PPG signal in response to the second pressurization complete signal;
the second blood pressure value and the second PPG signal are stored.
12. The blood pressure calibration method of claim 10, wherein the one or more pressure values further comprise a second pressure value, the second pressure value being greater than the first pressure value, the first pressurization notification comprising the first pressure value and the second pressure value, the method further comprising:
after ending measuring the first blood pressure value and acquiring the first PPG signal, sending a second pressurization notification to the pressurization device; the second pressurization notification is used for notifying the pressurization device to pressurize according to the second pressure value;
receiving a second pressurization completion signal sent by the pressurization device, the second pressurization completion signal being used to inform the blood pressure measurement apparatus that the pressurization device has completed pressurization according to the second pressure value;
measuring a second blood pressure value and acquiring a second PPG signal in response to the second pressurization complete signal;
the second blood pressure value and the second PPG signal are stored.
13. The blood pressure calibration method of any one of claims 10-12, wherein the obtaining a user blood pressure value comprises:
Acquiring a user blood pressure value from the pressurizing device; or alternatively
Measuring and acquiring a blood pressure value of a user through a PPG detection unit of the blood pressure measuring device; or alternatively
And obtaining the blood pressure value of the user through the micropump and the balloon measurement of the blood pressure measuring device.
14. The blood pressure calibration method of any one of claims 10-13, wherein the method further comprises:
updating the PPG model according to all stored blood pressure values and PPG signals;
and measuring the blood pressure of the user according to the updated PPG model.
15. The blood pressure calibration method of any one of claims 10-14, wherein:
the first part is a wrist and the second part is an upper arm.
16. The blood pressure calibration method of any one of claims 10-15, wherein measuring a first blood pressure value and acquiring a first PPG signal in response to the first pressurization complete signal comprises:
controlling a micropump of the blood pressure measurement device to inflate a bladder of the blood pressure measurement device to measure the first blood pressure value in response to the first pressurization completion signal;
after the balloon is deflated, the first PPG signal is acquired by a PPG sensor of the blood pressure measuring device.
17. The blood pressure calibration method of any one of claims 10-16, wherein the sending a first pressurization notification to the pressurization device comprises:
displaying a first pressurization prompt interface, wherein the first pressurization prompt interface is used for prompting the start of pressurization;
receiving a first confirmation operation of a user;
the first pressurization notification is sent to the pressurization device in response to a first confirmation operation by the user.
18. The blood pressure calibration method of any one of claims 10-17, wherein the determining one or more pressure values from pre-stored PPG model parameters and the abnormal blood pressure values comprises:
determining one or more calibrated blood pressure values according to the PPG model parameters and the abnormal blood pressure values;
one or more of the pressure values are determined from one or more of the calibrated blood pressure values, one for each calibrated blood pressure value.
19. A blood pressure measurement device, comprising at least one processor, a memory, and a communication interface;
the at least one processor is coupled with the memory and the communication interface;
the memory is used for storing instructions, the processor is used for executing the instructions, and the communication interface is used for communicating with the pressurizing device under the control of the at least one processor;
The instructions, when executed by the at least one processor, cause the at least one processor to perform the blood pressure calibration method of any one of claims 10 to 18.
20. A computer storage medium comprising computer instructions which, when run on a blood pressure measurement device, cause the blood pressure measurement device to perform the blood pressure calibration method of any one of claims 10 to 18.
21. A computer program product comprising program code which, when executed by a processor in a blood pressure measuring device, implements a blood pressure calibration method according to any of claims 10 to 18.
CN202210357036.XA 2022-03-31 2022-03-31 Blood pressure calibration system, blood pressure calibration method and device thereof Pending CN116919365A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210357036.XA CN116919365A (en) 2022-03-31 2022-03-31 Blood pressure calibration system, blood pressure calibration method and device thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210357036.XA CN116919365A (en) 2022-03-31 2022-03-31 Blood pressure calibration system, blood pressure calibration method and device thereof

Publications (1)

Publication Number Publication Date
CN116919365A true CN116919365A (en) 2023-10-24

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Family Applications (1)

Application Number Title Priority Date Filing Date
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Country Status (1)

Country Link
CN (1) CN116919365A (en)

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