CN116898494A

CN116898494A - Sample collector and endoscope

Info

Publication number: CN116898494A
Application number: CN202311176844.7A
Authority: CN
Inventors: 周震华; 唐鹏; 张翔
Original assignee: Hunan Vathin Medical Instrument Co Ltd
Current assignee: Hunan Vathin Medical Instrument Co Ltd
Priority date: 2023-09-13
Filing date: 2023-09-13
Publication date: 2023-10-20
Anticipated expiration: 2043-09-13
Also published as: CN116898494B

Abstract

The invention provides a sample collector and an endoscope, relates to the technical field of endoscopes, and solves the problem that sample collection is inconvenient in the prior art. The sample collector is used for an endoscope, the base body is provided with a main channel and a mounting through hole which are intersected, the main channel can be connected with the instrument nozzle, and the treatment instrument can release samples at the intersection of the main channel and the mounting through hole; the sample receiving container is detachably connected with the matrix and is in butt joint with the mounting through hole through the container opening; the sealing piece seals and cuts off the container mouth from the mounting through hole in the mounting through hole; the driving piece can drive the puncture piece in the installation through hole to move from a first position to a second position relative to the installation through hole, the sealing piece is complete under the condition of the first position, the puncture piece pierces the sealing piece under the condition of the second position, and the driving piece penetrates into the puncture piece, so that a sample can be pushed into the sample collecting container; the first return spring is capable of driving the penetrating member to return from the second position to the first position. The invention can lead the treatment instrument to return to the intersection to release the sample when not being pulled away from the endoscope, so that the sample collection process is more convenient.

Description

Sample collector and endoscope

Technical Field

The invention relates to the technical field of endoscopes, in particular to a sample collector and an endoscope.

Background

The endoscope is used for directly entering the natural cavity of the human body for examination, providing sufficient diagnosis information for doctors, and if necessary, inserting treatment instruments to complete sampling or treatment of lesion sites. The treatment instrument is required to be inserted into a lesion in a human body through an instrument channel in an endoscope to sample or deliver a therapeutic substance.

In the sampling process by using the treatment instrument, the treatment instrument is required to be pulled out of the instrument channel to the external environment after the sampling is successful, the taken sample is released and placed in the instrument tray, then the sample is placed in the sample container by using a tool clamp such as forceps, and the sample collecting process is complicated.

The invention aims to design a sample collector and an endoscope, which are used for solving the problem of inconvenient collection of samples.

The invention is realized by the following technical scheme:

the invention provides a sample collector, which is used for an endoscope, and comprises an instrument nozzle, wherein the sample collector comprises a base body, a puncture piece, a sealing piece, a sample collection container, a driving piece and a first reset spring; an intersecting main channel and a mounting through hole are arranged in the matrix, the main channel is used for abutting the instrument nozzle, and the intersection of the main channel and the mounting through hole can allow a treatment instrument penetrating into the main channel to release a sample; the sample receiving container is detachably connected with the base body, and a container opening of the sample receiving container is in butt joint with the mounting through hole; the sealing piece is arranged in the mounting through hole and seals and cuts off the container opening and the mounting through hole; the puncture piece is arranged as a ring cutter which is coaxial with the installation through hole and axially penetrates through the installation through hole, and the puncture piece is arranged in the installation through hole and can move from a first position to a second position relative to the installation through hole; the puncture element is in the first position, the sealing element is complete, and the puncture element is in the second position, the puncture element punctures the sealing element to form a puncture part; the sample receiving container is capable of receiving the sample through the puncture site; the driving piece is movably inserted into the mounting through hole and can reciprocate relative to the mounting through hole, and the driving piece is used for driving the puncture piece to move from the first position to the second position; the drive member being capable of penetrating into the piercing member to urge the sample retained in the piercing member toward the sample receiving container with the piercing member in the second position; the two ends of the first reset spring are respectively connected with the base body and the puncture piece, and the first reset spring can drive the puncture piece to reset to the first position under the condition that the driving piece drives the puncture piece to move from the first position to the second position.

Further, in order to better realize the invention, the following arrangement structure is adopted: the puncture member includes a cutting edge extending continuously along a circumference of the mounting through hole, the cutting edge being oriented toward the sample container.

Further, in order to better realize the invention, the following arrangement structure is adopted: the puncture member comprises a plurality of cutting parts, the sub-cutting edges of the cutting parts extend obliquely, and all the cutting parts are arranged in sequence along the mounting through holes Zhou Xiangyi to form annular cutting teeth facing the sample container.

Further, in order to better realize the invention, the following arrangement structure is adopted: the piercing member is provided with a notch separating the leading and trailing portions of the cutting edge.

Further, in order to better realize the invention, the following arrangement structure is adopted: the inner diameter of the puncture member is equal to or smaller than the aperture of the mounting through hole.

Further, in order to better realize the invention, the following arrangement structure is adopted: the sample collector also comprises a first plug body which is detachably connected to the extending end of the driving piece, and the first plug body is in dynamic sealing fit with the wall of the mounting through hole; the driving piece drives the puncture piece to move from the first position to the second position, and the first plug body can enter the puncture piece to be contacted with the inner wall of the puncture piece so as to drive the puncture piece to move towards the sample collection container; the driving piece drives the puncturing piece to move from the first position to the second position, the first plug body enters the sample collection container and is detachably and hermetically connected with the hole wall of the container opening, and the first plug body can be separated from the driving piece, the puncturing piece and the base body along with the sample collection container detached from the base body.

Further, in order to better realize the invention, the following arrangement structure is adopted: the driving piece can reciprocate relative to the base body; the sample collector also comprises a first reset spring, wherein two ends of the first reset spring are respectively connected with the base body and the puncture piece, and the first reset spring can drive the puncture piece to reset towards the first position under the condition that the driving piece drives the puncture piece to move from the first position to the second position; and/or, the sample collector further comprises a second reset spring, wherein two ends of the second reset spring are respectively connected with the base body and the driving piece and used for driving the driving piece to reset towards the direction far away from the sample collector.

Further, in order to better realize the invention, the following arrangement structure is adopted: one end of the first plug body is provided with a handle, and under the condition that the first plug body is in sealing connection with the container mouth, the handle is positioned outside the sample collection container.

Further, in order to better realize the invention, the following arrangement structure is adopted: the sample collector also comprises a second plug body connected to the extending end of the driving piece, the second plug body is in dynamic sealing fit with the hole wall of the mounting through hole, and the second plug body can move along with the driving piece to drive the puncture piece to move; and/or, the sample collector further comprises a container cover connected with the sample collector, wherein the container cover is matched with the container opening and is used for being detachably and hermetically connected with the container opening.

Further, in order to better realize the invention, the following arrangement structure is adopted: and under the condition that the driving piece drives the puncture piece to move from the first position to the second position, dynamic sealing fit is formed between the driving piece and the hole wall of the mounting through hole at two opposite sides of the main channel.

Further, in order to better realize the invention, the following arrangement structure is adopted: the seal is secured to the sample receiving container.

The invention also provides an endoscope, which comprises a handle and the sample collector, wherein an outlet of a main channel arranged in a matrix of the sample collector is detachably connected with an instrument nozzle of the endoscope.

The invention has the following advantages and beneficial effects:

according to the invention, the main channel arranged in the matrix of the sample collector can penetrate into the treatment instrument, the treatment instrument for taking the sample can release the sample at the intersection of the main channel and the mounting through hole, and then the driving piece can drive the puncture piece to puncture the sealing piece, so that the inner cavity of the sample collector is communicated with the mounting through hole, and the released sample can enter into the inner cavity of the sample collector through the puncture part on the sealing piece to be collected. Thus, in the process of collecting the sample, the sample does not need to be exposed to the indoor environment, so that the sample can be effectively prevented from being polluted, the sample can be prevented from polluting the indoor environment, and meanwhile, the sample does not need to be clamped and collected into the container by using tools such as forceps, so that the collection process does not involve switching among a treatment instrument, a clamping tool and an endoscope, and the process from taking the sample collection container to opening the sample collection container, and the process of collecting the sample is more convenient. When the puncture piece is in the second position, the driving piece can penetrate into the puncture piece, the sample reserved in the puncture piece is pushed into the sample collection container, so that the sample is better prevented from staying in the puncture piece, meanwhile, the first reset spring can reset the puncture piece to the first position, the puncture piece can return to the original position after completing one puncture, the main channel is smooth, the next sample collection after replacing a new sample collection container 14 can be conveniently performed, and the puncture piece reset to the first position can enable the driving piece to extend deeper into the puncture piece, so that the effect of pushing the sample out of the puncture piece is improved.

In addition, because the main channel is used for being in butt joint with the instrument mouth of the endoscope, the sample collector can guide the treatment instrument penetrating into the main channel to move towards the distal end outlet of the instrument channel of the endoscope, so that the treatment instrument can return to the main channel along a way to release samples after sampling is finished, complicated path guiding operation on the treatment instrument is not needed, and the sample collecting process is convenient.

In addition, the sealing piece seals and cuts off the container mouth and the installation through hole of the sample receiving container, so that the sample receiving container is sealed and cut off with the channel inside the matrix before collecting samples, and medicines stored in the sample receiving container cannot leak into the main channel in the process of sampling a treatment instrument, so that the conditions of entering a human body can be guaranteed, and the safety of using the sample receiving container can be guaranteed.

Drawings

In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 illustrates the exterior configuration of the cartridge in some embodiments with the drive member in an initial position;

FIG. 2 is a schematic view of the external appearance structure of the base body;

FIG. 3 shows the assembled structure of the base body and the piercing member;

FIG. 4 illustrates an exploded view of a sample receiver in some embodiments;

FIG. 5 illustrates the structure of a piercing member in some embodiments;

FIG. 6 shows the cartridge with the push rod detachably connected to the first plug body, with the internal structure of the drive member in the home position;

FIG. 7 illustrates the appearance of the cartridge in some embodiments with the drive member in the critical position;

FIG. 8 shows the cartridge with the plunger removably attached to the first plug body, with the internal structure of the drive member in the critical position;

FIG. 9 illustrates the appearance of the cartridge in some embodiments with the drive member in the end position;

FIG. 10 shows the cartridge with the push rod detachably connected to the first plug body, with the internal structure of the drive member in the end position;

FIG. 11 shows the internal structure of the cartridge when the spike is returned to the first position on the basis of FIG. 10;

FIG. 12 shows the appearance of a sample container with a first stopper sealing the mouth of the container;

FIG. 13 is an exploded view of FIG. 12;

FIG. 14 is a schematic view of a piercing seal (dashed lines in the figure indicate correspondence between two sides of a notch and the seal);

FIG. 15 illustrates an external appearance of a cartridge in some embodiments configured with a second return spring;

FIG. 16 shows the cartridge with the push rod non-removably attached to the second plug body, with the internal structure of the drive member in the home position;

FIG. 17 is a view showing the external appearance of a sample container with a container lid for sealing a container opening;

fig. 18 is a schematic view of the structure of the endoscope of the present application.

Marked in the figure as:

10. a sample collector;

11. a base; 11a, a main body part; 11b, an end cap portion; 111. a main channel; 112. mounting through holes; 113. a second protrusion;

12. a piercing member; 121. a cutting section; 122. a notch;

13. a seal;

14. a sample collection container; 141. a container cover;

15. a driving member; 151. a push rod; 1511. a seal ring mounting groove; 1512. an avoidance groove; 152. a pole cap; 1521. a first protrusion;

16. a first plug body; 161. a handle; 162. a boss portion; 163. a groove;

17. a second plug body;

18. a first return spring;

19. a second return spring;

20. a handle.

Detailed Description

In order to make the objects, technical solutions and advantages of the present application more apparent, the technical solutions of the present application will be described in detail below. It will be apparent that the described embodiments are only some, but not all, embodiments of the application. All other embodiments, based on the examples herein, which are within the scope of the application as defined by the claims, will be within the scope of the application as defined by the claims.

In the description of the present invention, it is to be noted that, unless otherwise indicated, the meaning of "plurality" means two or more; the terms "upper," "lower," "left," "right," "inner," "outer," "front," "rear," "head," "tail," and the like are used as an orientation or positional relationship based on that shown in the drawings, merely to facilitate description of the invention and to simplify the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the invention. Furthermore, the terms "first," "second," "third," and the like are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it should also be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium. The specific meaning of the above terms in the present invention can be understood as appropriate by those of ordinary skill in the art.

In various embodiments of the present application, "proximal" and "distal" refer to the fact that the end of the endoscope that is closer to the user is designated as "proximal" and the end that is farther from the user is designated as "distal" in the environment of use, wherein "distal" and "proximal" also correspond to the context of use, respectively.

In one aspect, the present application provides a sample collector, particularly configured as follows:

as can be seen in fig. 17, the cartridge 10 is for an endoscope, wherein the endoscope comprises an instrument nozzle as a joint for external connection of an instrument channel.

The function of the cartridge 10 is to interface with the inlet of the instrument channel of the endoscope to provide a penetration channel for the treatment instrument, while the channel provided by the cartridge 10 supports the proximal end of the treatment instrument, guides the treatment instrument into the instrument channel smoothly and moves to the distal outlet of the instrument channel for sampling operations. The treatment instrument may reciprocate along the instrument path and path provided by the cartridge 10 to effect insertion, sampling, lofting, and extraction.

As shown in fig. 6, the cartridge 10 includes a base 11, a piercing member 12, a sealing member 13, a cartridge 14, and a driving member 15.

The base 11 provides a basis for mounting the puncture member 12, the sealing member 13, the sample collection container 14 and the driving member 15, the driving member 15 can move relative to the base 11, and the sealing member 13 for sealing and isolating the sample collection container 14 and the internal channel of the base 11 is pierced by driving the puncture member 12 to move, so that the sample remained in the base 11 can enter the sample collection container 14 for collection. The sample container 14 can be detached from the base 11 and the collected sample can be taken away for testing. The manner of collection by allowing the sample to migrate within the channel provided within the base 11 to the sample receiving container 14 will allow the sample to be collected without exposure to an external environment, such as an operating room environment.

Specifically, as shown in fig. 3, the channels provided in the base 11 include a main channel 111 and a mounting through hole 112, and the main channel 111 and the mounting through hole 112 are disposed intersecting. Preferably, the main channel 111 and the mounting through hole 112 are orthogonal as shown in fig. 3, and a middle section of the mounting through hole 112 intersects with a middle section of the main channel 111 to form an intersection. Generally, as shown in fig. 2, the appearance of the base 11 is designed to be a four-way structure in cooperation with the orthogonal main channel 111 and the mounting through hole 112.

As shown in fig. 3, in the base 11, the main passage 111 has one inlet and one outlet. In fig. 3, the inlet of the main channel 111 is on the right and the outlet is on the left. The main channel 111 is used for communicating with the instrument channel of the endoscope, specifically, the interface arranged at the outlet of the main channel 111 is in butt joint with the instrument mouth on the endoscope to complete the butt joint communication with the inlet of the instrument channel, the main channel 111 is also used for penetrating the treatment instrument, and the treatment instrument can penetrate into the main channel 111 from the inlet of the main channel 111 and penetrate out from the outlet of the main channel 111. The outlet of the main channel 111 interfaces with the inlet of the instrument channel, allowing the treatment instrument to pass through the outlet of the main channel 111, then into the instrument channel, and finally through the distal outlet of the instrument channel to the target site for sampling.

As shown in fig. 3, the outlet of the main channel 111 is provided with a clamping interface with a clamping groove, and the clamping interface is matched with the instrument mouth on the handle 20 of the endoscope, so that the sample collector 10 can be simply and conveniently clamped on the instrument mouth formed by the handle 20 through the outlet of the main channel 111 of the base body 11 as shown in fig. 18, and can be detached from the instrument mouth at any time. The sample collector 10 can be separated from the handle 20 of the endoscope before use, can be stored separately, and can be detached from the instrument mouth on the handle 20 after use, so that the sample collector 10 has the advantages that the conventional endoscopic structure can be not required to be modified, and the conventional instrument mouth on the handle 20 of the endoscope can be used for attaching the sample collector 10 to achieve the purpose of conveniently collecting samples, thereby being more beneficial to popularization.

The entrance of the main channel 111 can be equipped with a rubber plug like the existing instrument plug, and the entrance of the main channel 111 can be plugged by the rubber plug under the condition that the treatment instrument is not penetrated into the main channel 111, so that on one hand, the pollutant can be prevented from entering the inside of the matrix 11, and on the other hand, the endoscope can be required to perform negative pressure suction operation, and the entrance of the main channel 111 is closed.

The space at the intersection of the main channel 111 and the mounting through hole 112 is large enough so that the sampling portion of the treatment instrument can be spread out when retreating to the intersection, releasing the acquired sample. Generally, as shown in fig. 3, the aperture of the mounting through hole 112 is larger than the aperture of the main channel 111, providing a sufficient upper space and lower space, or both spaces, for deployment of the treatment instrument, and providing a sufficient mounting space for mounting the driver 15 and the sample container 14.

As shown in fig. 13, the sample container 14 has a cavity for collecting a sample and a container opening exposing the cavity, and may be used for storing a medicine. As shown in fig. 1, 4 and 10, the sample container 14 is shown as a bottle having a large axial dimension and a small radial dimension, but the sample container 14 may be a basin-shaped container or a container having another shape.

As shown in fig. 6, the sample container 14 is detachably connected to the base 11. Generally, the sample receiving container 14 is disposed coaxially with the mounting through-hole 112 such that the container mouth of the sample receiving container 14 is upwardly abutted with the bottom end of the mounting through-hole 112 to facilitate receiving the sample. Generally, a clamping interface is formed at the bottom end of the mounting through hole 112, an adaptive clamping connector is formed at the container opening of the sample receiving container 14, and the container opening of the sample receiving container 14 is inserted into the clamping interface at the bottom end of the mounting through hole 112 to be mutually matched and clamped together. The sample receiving container 14 may receive the sample released into the intersection of the main channel 111 and the mounting through hole 112 below the main channel 111. The sample container 14 may store, but is not limited to, a liquid medicament for better holding the sample. For example, the sample container 14 may be further used to store a chemical solution for sample pretreatment, so that the sample can be pretreated in time, which is beneficial to shortening the sample inspection time and improving the sample inspection efficiency.

The seal 13 is a pierceable, preferably thinner, entity, such as a plastic film, paper, sheet of plastic, or the like, which can be used to seal the mouth of the sample container 14, and is easily pierced. As shown in fig. 6, the seal member 13 is provided in the mounting through hole 112 between the main channel 111 and the sample container 14, and seals the container mouth of the sample container 14 from the upper mounting through hole 112. Preferably, as shown in fig. 6 and 13, the sealing member 13 is directly fixed at the end of the container mouth of the sample receiving container 14, the contour shape of the sealing member 13 is adapted to the mouth shape of the container mouth of the sample receiving container 14, and the container mouth is completely sealed, so that the sample receiving container 14 is provided with the sealing member 13, and the sealing member 13 can move together with the sample receiving container 14 to seal the container mouth of the sample receiving container 14, so that the sample receiving container 14 can be pre-filled with the required medicament for storage, and temporary filling during sample receiving can be avoided, thereby saving time during operation.

As shown in fig. 6 and 10, the puncture element 12 is integrally disposed in the mounting through-hole 112 and is movable from the first position to the second position with respect to the mounting through-hole 112. Typically, the bottom end of the piercing element 12 is configured to pierce the sealing element 13, for example, it is configured as a pointed tip, which may be a tapered piercing needle extending axially downward, or may be configured as a flat head, to which sufficient axial force is applied by contacting the sealing element 13 to break the sealing element 13, or may be configured as a plate extending obliquely in the axial direction along the mounting through hole 112, or the like. As shown in fig. 10, the puncture member 12 has a flange portion extending outward, and the puncture member 12 is radially mounted on the base body 11 by the flange portion being inserted into a movable ring groove provided in the wall of the mounting through hole 112, so that the puncture member 12 can be moved in the axial direction of the mounting through hole 112. In order to facilitate the installation of the puncture outfit 12, as shown in fig. 4 and 10, the base 11 is composed of a main body 11a and an end cap 11b assembled along the axial direction of the installation through hole 112, a section of socket hole with an enlarged aperture is provided at the bottom end of the installation through hole 112 on the main body 11a, the end cap 11b is a flange-like structural member which is sleeved at the bottom of the main body 11a, a through hole with a reduced aperture to the aperture of the installation through hole 112 is formed at the bottom end of the socket hole, so that a ring groove with a certain axial length is formed at the section of the socket hole, which is recessed in the installation through hole 112, and the flange part of the puncture outfit 12 is located in the ring groove and is limited to move along the axial direction of the installation through hole 112 in the ring groove.

Moving in the axial direction of the mounting through hole 112, the sealing member 13 is intact in the case of the first position of the piercing member 12, and in this position, the piercing member 12 is in direct contact with the sealing member 13, for example. The seal 13 is pierced once by the piercing element 12 during movement from the first position to the second position. With the piercing element 12 in the second position, the piercing element 12 has moved a distance, and the piercing seal 13 forms the piercing site. After the seal 13 is pierced by the piercing member 12, the formed piercing site is of sufficient size to allow the sample receiving container 14 to receive a sample through the piercing site. For some seals 13 that employ elastomeric materials, the seal 13 will tear and expand radially outwardly at the puncture site after the puncture member 12 pierces the seal 13, such that the puncture site has an area greater than the cross-sectional area of the puncture member 12, which seal 13 will facilitate the passage of the sample through the puncture site.

The driving member 15 is movably connected to the base 11, and the bottom end of the driving member 15 is matched with the puncturing member 12, so that the driving member 15 can drive the puncturing member 12 to move from the first position to the second position by using the movement of the driving member 15 relative to the base 11. The driver 15 may be inserted coaxially into the mounting hole 112 as shown in fig. 6, or may be inserted eccentrically into the mounting hole 112, or may be inserted into a dedicated guide hole formed in the base 11 at a different place, so long as the driver 15 is moved to a specific position, and is brought into contact with the puncture element 12 to drive the puncture element 12 to move relative to the mounting hole 112.

Preferably, the driving member 15 is coaxially inserted in the mounting through hole 112.

The following description continues with the preferred option of coaxially inserting the driver 15 into the mounting through hole 112.

The driving member 15 is movable relative to the mounting through hole 112 from a start position, which is the position at which the driving member 15 is first used, to an end position, which is the position at which the driving member 15 drives the penetrating member 12 to the second position. In the case of the initial position of the driving member 15, as shown in fig. 6, the projecting end of the driving member 15 is located at the upper side of the main channel 111, leaving the main channel 111 so that the treatment instrument penetrating into the main channel 111 does not interfere with the driving member 15.

In this embodiment, the main channel 111 provided in the base 11 of the sample collector 10 can penetrate into the treatment device, and can enable the treatment device for obtaining the sample to release the sample at the intersection of the main channel 111 and the mounting through hole 112, then the driving member 15 passes through the main channel 111 to descend and connect with the puncturing member 12, and drives the puncturing member 12 to pierce the sealing member 13 downwards, so that the inner cavity of the sample collector 14 is communicated with the mounting through hole 112, and the released sample can enter into the inner cavity of the sample collector 14 through the puncturing part on the sealing member 13 to be collected. Thus, in the process of collecting the sample, the sample does not need to be exposed to the indoor environment, so that the sample can be effectively prevented from being polluted, the sample can also be prevented from polluting the indoor environment, and meanwhile, the sample does not need to be clamped and collected into the container by using tools such as forceps, so that the collection process does not involve switching among a treatment instrument, a clamping tool and an endoscope, and the process from taking the sample collection container 14 to opening the sample collection container 14, and the process of collecting the sample is more convenient. In addition, since the main channel 111 is used for being in butt joint with the instrument nozzle of the endoscope, the sample collector 10 can guide the treatment instrument penetrating into the main channel to move towards the distal outlet of the instrument channel of the endoscope, so that the treatment instrument can return to the main channel 111 in one way along a path after the sampling is finished, the sample is released at the intersection of the main channel 111 and the mounting through hole 112, and the complex path guiding operation on the treatment instrument is not needed, so that the sample collecting process is convenient. In addition, the sealing member 13 seals and cuts off the container mouth of the sample receiving container 14 and the mounting through hole 112, so that the sample receiving container 14 is sealed and cut off with the channel inside the base body 11 before collecting samples, and the medicine stored in the sample receiving container cannot leak into the main channel in the process of sampling the treatment instrument, so that the medicine enters the human body, and the safety of using the sample receiving container can be ensured.

According to some alternative embodiments, as shown in fig. 4, 6 and 10, the driving member 15 includes a push rod 151 coaxially inserted into the mounting through hole 112, the push rod 151 is a straight rod member, and the bottom end of the push rod 151 is inserted into the mounting through hole 112 and movably guided and matched with the wall of the mounting through hole 112 through the outer circumferential surface. The bottom surface of the plunger 151 has a certain area, and during the movement of the driving member 15 from the initial position to the final position, the plunger 151 reaches a critical position, specifically, during this process, the plunger 151 passes through the main channel 111, and then moves to the critical position shown in fig. 7 and 8 to connect with the piercing member 12, and then from the critical position, pushes the piercing member 12 and the sample gradually closer to the sealing member 13 until the piercing member 12 pierces the sealing member 13. Plunger 151 may move piercing member 12 by pushing against the tip of piercing member 12 present in mounting hole 112, or may move piercing member 12 by friction provided by contact with the side of piercing member 12.

Preferably, as shown in fig. 1, 4, 6 and 10, the driving member 15 further includes a lever cap 152, and a middle portion of the lever cap 152 is coaxially fixed to the protruding end of the push rod 151, and a radial dimension of the lever cap 152 is larger than a radial dimension of the push rod 151 to provide a larger operation surface. The inner wall of the lever cap 152 is provided with a first protrusion 1521, and the outer wall of the base 11 is provided with a second protrusion 113. The first protrusion 1521 is an annular rib and the second protrusion 113 is an annular rib. When the driving member 15 moves from the initial position to the final position, as shown in fig. 10, the first protrusion 1521 can abut against the second protrusion 113 from an end close to the sample container 14 to block the push rod 151 from moving away from the sample container 14. In this embodiment, the lever cap 152 can cooperate with the second protrusion 113 provided on the outer wall of the base 11 through the first protrusion 1521 on the inner wall thereof to generate a retaining effect, so as to maintain the driving member 15 at the end position.

According to some alternative embodiments, as shown in fig. 4, 5, 6 and 14, the piercing member 12 is provided as a ring cutter, the piercing member 12 is coaxially disposed with the mounting through hole 112 and extends circumferentially along the mounting through hole 112 to form an axially through annular structure, and the cutting edge of the piercing member 12 extends continuously circumferentially along the mounting through hole 112. As shown in fig. 6, the cutting edge of the lancet 12 is disposed toward the sample receiving container 14. In the case of providing the piercing member 12 as a circular cutter with a cutting edge extending continuously along the circumference of the mounting through hole 112, the piercing member 12 will be able to pierce the sealing member 13 in a larger range, forming a larger piercing portion, so as to enhance the effect of collecting the sample in the sample receiving container. In addition, the piercing member 12, which is a ring cutter, can reduce the obstructing effect on the sample so that the sample can pass through the through hole of the piercing member 12 and then enter the sample collection container 14 from the piercing portion on the sealing member 13.

Preferably, the driving member 15 movably inserted in the mounting hole 112 is capable of penetrating the penetrating member 12 to push the sample remaining in the penetrating member 12 toward the sample receiving container 14 when the penetrating member 12 is driven to move from the first position to the second position, so that the sample is prevented from being stopped in the penetrating member 12.

In general, the cutting edge of the penetrating member 12 may be a complete annular cutting edge or an incomplete annular cutting edge.

Preferably, as shown in FIG. 5, the cutting edge of the penetrating member 12 is in the form of an annular tooth. Specifically, the bottom of the penetration member 12 has a plurality of cutting portions 121, the sub-cutting edges of the cutting portions 121 extend obliquely, and all the cutting portions 121 are arranged in order along the mounting through hole 112 Zhou Xiangyi. The cutting edges of the piercing elements 12 are distributed over all the cutting portions 121 in the form of sub-cutting edges which, in addition to extending circumferentially, extend obliquely in the axial direction, so that all the cutting portions 121 combine to form an annular cutting tooth directed towards the sample holder 14. The annular cutting teeth may each cut the seal 13 circumferentially by means of a cutting edge extending obliquely to the corresponding position of the seal 13 during penetration of the seal 13, which may allow the penetration member 12 to penetrate the seal 13 more easily.

Preferably, the piercing member 12 is provided with a notch 122, and as shown in fig. 5, for example, in which the cutting edge of the piercing member 12 is in the form of a ring tooth, the notch 122 is formed between two adjacent cutting portions 121 of the piercing member 12, and separates the leading and trailing portions of the cutting edge of the piercing member 12 so that the cutting edge is not a complete revolution. In the case of the piercing member 12 being a circular cutting knife, the notch 122 is provided so that the cutting edge has a breaking position in the circumferential direction, as shown in fig. 14, the position of the notch 122 does not cut the sealing member 13, and thus, the cut portion of the sealing member 13 has a section connected to the main body, so that the cut portion is not cut off from the main body of the sealing member 13, and the problem of falling into the cavity of the sample receiving container 14 is avoided, and the contact between the collected sample and the medicament is not affected.

According to some alternative embodiments, as shown in fig. 6 and 8, the piercing member is a circular cutter, and the inner diameter of the piercing member 12 is equal to or smaller than the aperture of the mounting through hole 112, so that the piercing member 12 does not exist in a portion inside the wall of the mounting through hole 112, at this time, the driving member 15 may extend into the through hole of the piercing member 12 through the plunger 151, contact with the inner wall of the piercing member 12, and drive the piercing member 12 to move by providing friction force. After the inner diameter of the puncture element 12 is equal to or smaller than the aperture of the mounting through hole 112, the inner diameter of the puncture element 12 is not larger than the aperture of the mounting through hole 112, so that the inner wall of the puncture element 12 does not protrude out of the mounting through hole 112, and the released sample is not blocked, so that the problem of remaining at the end of the puncture element 12 is solved, and the sample is facilitated to enter the sample receiving container 14 more.

Preferably, as shown in fig. 4, 6, 8, 10 and 11, the sample collector 10 further includes a first plug 16 detachably connected to the extending end of the driving member 15, and the first plug 16 is an elastomer, and is in dynamic sealing fit with the wall of the mounting through hole 112 through the outer peripheral surface. The first plug 16 is in direct contact with the piercing member 12 instead of the driving member 15 itself. The first plug 16 has an outer diameter larger than the aperture of the through-hole of the puncture member 12 and the aperture of the container mouth of the sample container 14 in a free state. The first plug 16 is detachably connected to the extending end of the driving member 15, so that the driving member 15 drives the puncturing member 12 to move from the first position to the second position through the first plug 16, and in the moving process, as shown in fig. 8 and 10, the first plug 16 can enter the puncturing member 12 and move relative to the puncturing member 12, and the puncturing member 12 is provided with friction force to drive the puncturing member 12 to move towards the sample container 14 through the contact between the outer peripheral surface and the inner wall of the puncturing member 12. As shown in fig. 10, when the driving member 15 drives the puncture member 12 from the first position to the second position through the first plug 16, the first plug 16 enters the container mouth of the sample container 14 and is detachably and hermetically connected to the wall of the container mouth through the outer peripheral surface. When the sample container 14 is detached from the base 11, the first stopper 16 can move along with the base 11 to be separated from the puncture element 12, thereby separating the driving element 15 and the base 11. In the process of driving the puncture member 12 to move from the first position to the second position, the driving member 15 drives the first plug body 16 to move, so that the first plug body 16 is driven to enter the through hole of the puncture member 12 which is arranged as a ring cutter, and the puncture member 12 is driven to move to the second position by the friction force provided by the contact of the first plug body 16 with the inner wall of the puncture member 12 and facing the sample receiving container 14, so that the process can sequentially complete the puncture of the sealing member and the sealing action of the container mouth of the sample receiving container. The first plug body 16 is driven by the driving member 15 to be installed in the container opening of the sample receiving container 14, and the container opening of the sample receiving container is sealed, so that after the sample receiving container is detached from the substrate, a plug or a cover seal is not required to be found, and the sample collecting process is quite convenient. In addition, the first plug body 16 is in dynamic sealing fit with the hole wall of the mounting through hole 112, so that the pushing effect can be achieved in the moving process, the scraping effect can be achieved on the hole wall of the mounting through hole 112, and the sample can enter the sample collecting container 14 more.

Preferably, as shown in fig. 12 and 13, a handle 161 protruding upward is provided at a central position of the tip of the first plug body 16 to provide a gripping portion for an operator. With the first plug 16 sealingly connected to the container mouth, the carrying handle 161 is located outside the sample container 14. In this embodiment, the handle protruding to the outside of the container mouth of the sample container can provide a holding portion for an operator, so as to facilitate pulling the first plug 16 from the sample container, and facilitate subsequent inspection of the sample stored in the sample container.

Preferably, the end of the carrying handle 161 remote from the sample container 14, i.e. the tip end thereof is provided with a flange portion protruding laterally in the radial direction, as shown in fig. 12 and 13, which flange portion makes the carrying handle 161 form a T-shaped structure. The flange provided at the end of the handle 161 provides more grip to facilitate better force application by the operator to easily remove the first plug 16 from the container 14.

Preferably, the middle position of the top end of the first plug body 16 is provided with a boss portion 162 protruding upward, and the handle 161 is connected to the top center position of the boss portion 162, as shown in fig. 10 and 12, and when the first plug body 16 is moved into the container mouth, a gap is formed between the outer peripheral surface of the boss portion 162 and the inner wall of the container mouth. The boss part 162 arranged on the first plug body 16 can further prolong the distance from the carrying handle 161 to the contact part between the first plug body 16 and the wall of the container mouth, increase the moment arm, and enable an operator to pull out the first plug body 16 more easily by properly shaking the carrying handle 161; in addition, the clearance formed between the boss 162 and the container mouth can ensure the shaking amplitude of the first plug 16, so as to ensure that the first plug 16 can be easily pulled out from the sample container 14.

Preferably, as shown in fig. 10, the middle position of the bottom end of the push rod 151 is provided with a avoidance groove 1512, and the depth of the avoidance groove 1512 is slightly larger than the height of the carrying handle 161, and the radial dimension is slightly larger than the radial dimension of the carrying handle 161. In the process of abutting the push rod 151 and the first plug body 16, the lifting handle 161 extends upwards into the avoiding groove 1512, so that when the first plug body 16 axially abuts against the push rod 151, the lifting handle 161 can enter the avoiding groove 1512, the assembly length is reduced, and the layout space is saved.

Preferably, as shown in fig. 10, a groove 163 is provided at a middle position of the bottom end of the first stopper 16. The recess 163 provided in the middle of the first stopper 16 may facilitate inward deformation of the sides of the first stopper 16 so that the piercing member 12 may more easily enter the through-hole of the piercing member 12 provided as a ring cutter and also into the mouth of the sample receiving container 14.

Of course, the sample collector 10 may be provided with the first plug 16 detachably connected to the driving member 15, and the first plug 16 may be replaced with the second plug 17 detachably connected to the driving member 15. Specifically, as shown in fig. 16, the sample collector 10 further includes a second plug body 17 connected to the extending end of the driving member 15, where the second plug body 17 is an elastic member and is fastened to the extending end of the push rod 151 of the driving member 15 by a fastening structure. The second plug 17 has an outer diameter larger than the bore diameter of the through hole of the piercing member 12 in the free state. The second plug body 17 is in dynamic sealing fit with the hole wall of the mounting through hole 112 through the outer peripheral surface of the second plug body 17, and the second plug body 17 can move along with the driving piece 15 to drive the puncture piece 12 to move.

It should be noted that the fact that the second plug 17 is not detachable from the driving member 15 means that the second plug 17 is not detached from the driving member 15 by itself for various reasons, such as detachment from the push rod 151, during normal operation of the driving member 15. The second plug 17 acts in the same way as the first plug 16 when the driving member 15 moves from the start position to the end position, and the second plug 17 returns along the path with the driving member 15 when the driving member 15 returns from the end position to the start position.

The driver 15 forms a sample pushing assembly with the stopper body for pushing the penetration member 12 and the sample.

Preferably, as shown in fig. 15 and 16, in the case of the sample collector 10 using the second plug 17, the container mouth of the sample collector 14 cannot be sealed after being detached from the base 11 due to the absence of the plug of the first plug 16 that can be separated from the driving member 15 to move with the sample collector 14, so that, in order to avoid the trouble of finding a cap, the container cover 141 is connected to the sample collector 14, and the container cover 141 is connected to the sample collector 14 by a flexible connecting band, and the container cover 141 is adapted to the container mouth, so that the container mouth can be sealed detachably after the sample collector 14 is detached from the base 11. The second plug body 17 is in dynamic sealing fit with the hole wall of the mounting through hole 112, so that the material pushing effect can be achieved in the moving process, the scraping effect can be achieved on the hole wall of the mounting through hole 112, and the sample can enter the sample collecting container 14 more. The container cover 141 is connected to the sample receiving container and moves along with the sample receiving container, so that after the sample receiving container is detached from the substrate, the container cover 141 can be used for covering the container mouth, and the situation of finding the cover to seal everywhere is avoided, so that the collection process is more convenient.

According to some alternative embodiments, the driving member 15 is reciprocally movable along the mounting through-hole 112 with respect to the base body 11 to enable sampling and sampling operations to be performed again. When the driving member 15 is connected to the first plug 16 or the second plug 17, the first plug 16 and the second plug 17 can reciprocate along the mounting through hole 112 along with the driving member 15. The sample collection process is repeated by replacing the sample collection container 14 on the base 11.

Preferably, as shown in fig. 16, the sample collector 10 further includes a first return spring 18, where the first return spring 18 is a helical compression spring, and is accommodated in a ring groove formed by a mounting through hole 112 in the base 11 and is simultaneously sleeved on the puncture member 12 that is a ring cutter, and the bottom end and the top end of the first return spring 18 are respectively abutted against the end cap portion 11b of the base 11 and the flange portion of the puncture member 12. The first return spring 18 can drive the penetrating member 12 to return to the first position in the case where the driving member 15 drives the penetrating member 12 from the first position to the second position.

Preferably, as shown in fig. 15 and 16, the sample collector 10 further includes a second return spring 19, where the second return spring 19 is a spiral compression spring, and is sleeved on the push rod 151 of the driving member 15, and the top end and the bottom end of the second return spring 19 respectively abut against the rod cap 152 and the base 11 of the driving member 15, so as to drive the driving member 15 to return in a direction away from the sample collector 14, i.e. return the push rod 151 to the initial position.

When the puncturing element 12 is in the second position, the first return spring 18 can return the puncturing element 12 to the first position, so that the puncturing element 12 is far away from the sample receiving container 14, and the first plug 16 can enter the container mouth of the sample receiving container 14 more to contact with the inner wall of the container mouth, so that the first plug 16 can be easily detached from the base 11 along with the sample receiving container 14, and the condition that the first plug 16 is left on the puncturing element 12 can be better avoided. The puncture part 12 and the driving part 15 which can be reset can return to the original positions by themselves after the puncture and sample collection operation is completed once and after the clamping relation between the driving part 15 and the base body 11 is released, so that the main channel is smooth, and the next sample collection can be conveniently performed after the new sample collection container 14 is replaced.

According to some alternative embodiments, the driving member 15 is in dynamic sealing engagement with the mounting through hole 112, such that when the driving member 15 drives the piercing member 12 from the first position to the second position, the dynamic sealing engagement is formed between the driving member 15 and the wall of the mounting through hole 112 on opposite sides of the main channel 111. Specifically, as shown in fig. 4, 6 and 10, two seal ring mounting grooves 1511 axially arranged are provided on the outer peripheral surface of the push rod 151 of the driving member 15, and seal rings are mounted in the seal ring mounting grooves 1511, so that the push rod 151 is in contact with the wall of the mounting through hole 112 through the mounted seal rings to realize sealing. Under the condition that the outer peripheral surface of the driving piece 15 is in dynamic sealing fit with the hole wall of the mounting through hole, when the driving piece 15 moves the puncture piece 12 to the second position, the intersection of the main channel and the mounting through hole can be plugged, so that when the base body is connected to the instrument nozzle through the main channel, one section of the main channel connected with the instrument channel is isolated from the outside, and the endoscope can perform negative pressure suction operation through the instrument channel. After the reset of the driving member 15, the main channel can be reused for sampling operations.

In another aspect, the present application provides an endoscope, particularly employing the following arrangement:

as shown in fig. 18, the endoscope includes a handle 20 and the cartridge 10 of any of the embodiments described above.

The cartridge 10 is detachably butt-jointed to the instrument tip of the endoscope through the outlet of the main channel 111 provided in the base 11 so that the main channel 111 communicates with the inlet of the instrument channel of the endoscope.

During the use process:

when the sample collector 10 is not used, as shown in fig. 6 (the sample collector 10 in which the push rod 151 is detachably connected with the first plug body 16) and fig. 17 (the sample collector 10 in which the push rod 151 is non-detachably connected with the second plug body 17), the container mouth of the sample collector 14 is inserted into the interface at the bottom end of the mounting through hole 112, is clamped and fixed, is in butt joint with the bottom orifice of the mounting through hole 112, and the push rod 151 is coaxially inserted into the mounting through hole 112 and is positioned at the upper side of the main channel 111, so that the intersection of the mounting through hole 112 and the main channel 111 is a relatively airtight space, and the internal sample can be effectively prevented from being polluted or polluting the environment.

Taking the sample collector 10 shown in fig. 6 as an example:

after the sampling of the treatment instrument is completed, the treatment instrument is withdrawn rearward, the sampling portion of the treatment instrument is withdrawn to the intersection position of the main channel 111 and the mounting through hole 112 and opened, and the sample is released. Thereafter, by pressing the plunger cap 152 to drive the plunger 151, the plunger 151 is moved from the initial position shown in fig. 6 to the position shown in fig. 10, and during the movement, the plunger 151 is gradually moved into the through hole of the piercing member 12 by pushing the first plug body 16, and by contacting the wall of the through hole of the piercing member 12, a downward friction force is provided, and when the friction force provided to the piercing member 12 is greater than the restoring force provided by the first restoring spring 18, the piercing member 12 starts to move downward toward the sample container 14. When the plunger 151 moves to the end position, as shown in fig. 10, the puncture member 12 enters the sample receiving container 14, the sealing member 13 is pierced, the sample falls into the cavity of the sample receiving container 14 through the piercing portion of the sealing member 13, at this time, the portion of the first stopper 16 also passes through the through hole of the puncture member 12 downwards and is plugged into the container mouth of the sample receiving container 14, meanwhile, the first return spring 18 is in the maximum compression state, the return force provided by the first return spring 18 for the puncture member 12 is greater than the friction force provided by the first stopper 16 for the puncture member 12, and the puncture member 12 starts to return upwards relative to the first stopper 16, and finally reaches the position shown in fig. 11.

When the push rod 151 is returned from the end position to the start position, the push rod is separated from the first plug body 16, and the first plug body 16 is left at the container opening of the sample container 14 to seal the sample container 14.

When it is necessary to carry out a sample in time, the sample container 14 is detached from the bottom of the mounting hole 112 of the base 11, and as shown in fig. 12, the detached sample container 14 is plugged with the first plug 16, and the handle 161 protrudes from the container mouth. The sample container 14 of the first plug 16 is pulled out by pulling the handle 161 in a substantially axial direction, as shown in fig. 13.

When the driving piece 15 is located at the end position, the hole walls of the mounting through holes 112 on the upper side and the lower side of the main channel 111 are sealed by the sealing rings mounted on the push rod 151, so that the substrate 11 can penetrate into the treatment instrument through the inlet of the main channel 111 to continue sampling operation, and negative pressure suction equipment can be connected to the suction nozzle of the endoscope for suction.

If the cartridge 10 is used in which the driving member 15 is not detachably connected to the second stopper 17 as shown in fig. 15 and 16, the second stopper 17 is returned along with the driving member 15 during the return of the driving member 15 from the end position to the start position. When the sample container 14 is detached from the bayonet at the bottom of the mounting hole 112 of the base 11, the container lid 141 shown in fig. 1, 15 and 16 is inserted into the container mouth of the sample container 14, and the container mouth is sealed to form the shape shown in fig. 17.

The foregoing is merely illustrative of the present invention, and the present invention is not limited thereto, and any person skilled in the art will readily recognize that variations or substitutions are within the scope of the present invention.

Claims

1. A sample collector, characterized in that: for an endoscope comprising an instrument nozzle, the cartridge (10) comprising a base body (11), a piercing member (12), a sealing member (13), a cartridge (14), a driving member (15) and a first return spring (18);

an intersecting main channel (111) and a mounting through hole (112) are arranged in the base body (11), the main channel (111) is used for abutting the instrument nozzle, and the intersection of the main channel (111) and the mounting through hole (112) can allow a treatment instrument penetrating into the main channel (111) to release a sample;

the sample receiving container (14) is detachably connected with the base body (11), and a container opening of the sample receiving container (14) is in butt joint with the mounting through hole (112);

the sealing piece (13) is arranged in the mounting through hole (112) and seals off the container opening from the mounting through hole (112);

The puncture element (12) is arranged as a ring cutter which is coaxial with the mounting through hole (112) and axially penetrates along the mounting through hole (112), the puncture element (12) is arranged in the mounting through hole (112) and can move between a first position and a second position relative to the mounting through hole (112); the puncture element (12) is complete with the sealing element (13) in the first position, and the puncture element (12) punctures the sealing element (13) to form a puncture site in the second position; the sample receiving container (14) is capable of receiving the sample through the puncture site;

the driving piece (15) is movably inserted into the mounting through hole (112) and can reciprocate relative to the mounting through hole (112), the driving piece (15) is used for driving the puncturing piece (12) to move from the first position to the second position, and the driving piece (15) can penetrate into the puncturing piece (12) under the condition of the second position so as to push the sample remained in the puncturing piece (12) to the sample receiving container (14);

the two ends of the first return spring (18) are respectively connected with the base body (11) and the puncture piece (12), and the driving piece (15) drives the puncture piece (12) to move from the first position to the second position, and the first return spring (18) can drive the puncture piece (12) to return to the first position.

2. A cartridge according to claim 1, wherein: the penetration member (12) includes a cutting edge extending continuously along a circumferential direction of the mounting through hole (112), the cutting edge being directed toward the sample container (14).

3. A cartridge according to claim 2, wherein: the puncture member (12) comprises a plurality of cutting parts (121), wherein sub cutting edges of the cutting parts (121) extend obliquely, and all the cutting parts (121) are sequentially arranged along the mounting through holes (112) Zhou Xiangyi to form annular cutting teeth facing the sample container (14);

and/or the number of the groups of groups,

-said piercing member (12) being provided with a notch (122), said notch (122) separating the leading and trailing portions of said cutting edge;

and/or the number of the groups of groups,

the inner diameter of the puncture member (12) is equal to or smaller than the aperture of the mounting through hole (112).

4. A cartridge according to claim 3, wherein: the sample collector (10) further comprises a first plug body (16) which is detachably connected to the extending end of the driving piece (15), and the first plug body (16) is in dynamic sealing fit with the wall of the mounting through hole (112); the driving piece (15) drives the puncture piece (12) to move from the first position to the second position, and the first plug body (16) can enter the puncture piece (12) to be contacted with the inner wall of the puncture piece (12) so as to drive the puncture piece (12) to move towards the sample receiving container (14); the driving piece (15) drives the puncturing piece (12) to move from the first position to the second position, the first plug body (16) enters the sample collection container (14) and is detachably and hermetically connected with the hole wall of the container mouth, and the first plug body (16) can be separated from the driving piece (15), the puncturing piece (12) and the base body (11) along with the sample collection container (14) detached from the base body (11).

5. The sample collector of claim 4 wherein: the sample collector (10) further comprises a second reset spring (19), wherein two ends of the second reset spring (19) are respectively connected with the base body (11) and the driving piece (15) and used for driving the driving piece (15) to reset in a direction away from the sample collector container (14).

6. The sample collector of claim 4 wherein: one end of the first plug body (16) is provided with a lifting handle (161), and under the condition that the first plug body (16) is in sealing connection with the container mouth, the lifting handle (161) is positioned outside the sample receiving container (14).

7. A cartridge according to claim 1, wherein: the sample collector (10) further comprises a second plug body (17) connected to the extending end of the driving piece (15), the second plug body (17) is in dynamic sealing fit with the hole wall of the mounting through hole (112), and the second plug body (17) can move along with the driving piece (15) to drive the puncture piece (12) to move.

8. A cartridge according to claim 1, wherein: the sample collector (10) further comprises a container cover (141) connected with the sample collector (14), wherein the container cover (141) is matched with the container opening and is used for being detachably and hermetically connected with the container opening.

9. A cartridge according to claim 1, wherein: the driving piece (15) drives the puncture piece (12) to move from the first position to the second position, and dynamic sealing fit is formed between the driving piece (15) and the hole wall of the mounting through hole (112) at two opposite sides of the main channel (111);

and/or the number of the groups of groups,

the sealing member (13) is fixed on the sample container (14).

10. An endoscope, characterized in that: comprising a handle (20) and a cartridge (10) according to any of claims 1-9, the outlet of a main channel (111) provided in the base body (11) of the cartridge (10) being detachably connected to the instrument mouth of the endoscope.