CN116870357A - Intelligent left ventricle auxiliary system - Google Patents
Intelligent left ventricle auxiliary system Download PDFInfo
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- CN116870357A CN116870357A CN202310838702.6A CN202310838702A CN116870357A CN 116870357 A CN116870357 A CN 116870357A CN 202310838702 A CN202310838702 A CN 202310838702A CN 116870357 A CN116870357 A CN 116870357A
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- 210000005240 left ventricle Anatomy 0.000 title claims abstract description 13
- 238000012544 monitoring process Methods 0.000 claims abstract description 221
- 239000008280 blood Substances 0.000 claims abstract description 183
- 210000004369 blood Anatomy 0.000 claims abstract description 183
- 230000036772 blood pressure Effects 0.000 claims abstract description 106
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 105
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 105
- 239000001301 oxygen Substances 0.000 claims abstract description 105
- 238000005086 pumping Methods 0.000 claims abstract description 74
- 230000001105 regulatory effect Effects 0.000 claims abstract description 39
- 238000001514 detection method Methods 0.000 claims abstract description 9
- 230000002861 ventricular Effects 0.000 claims description 14
- 230000000630 rising effect Effects 0.000 claims description 12
- 230000017531 blood circulation Effects 0.000 claims description 8
- 238000005111 flow chemistry technique Methods 0.000 claims description 5
- 238000005070 sampling Methods 0.000 claims description 4
- 238000012935 Averaging Methods 0.000 claims description 2
- 230000008859 change Effects 0.000 description 11
- 238000004458 analytical method Methods 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 4
- 230000036541 health Effects 0.000 description 3
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- 210000000709 aorta Anatomy 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000004217 heart function Effects 0.000 description 2
- 206010019280 Heart failures Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
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- 210000000624 ear auricle Anatomy 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
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- 238000010606 normalization Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
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- 238000011897 real-time detection Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
- A61M60/178—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/515—Regulation using real-time patient data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/515—Regulation using real-time patient data
- A61M60/523—Regulation using real-time patient data using blood flow data, e.g. from blood flow transducers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/515—Regulation using real-time patient data
- A61M60/531—Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
Abstract
The application relates to the technical field of medical treatment, in particular to an intelligent left ventricle auxiliary system. The system comprises: the data detection module is used for collecting blood pressure monitoring data and blood oxygen monitoring data of a patient during operation; the monitoring module is used for feeding the blood pressure monitoring data and the blood oxygen monitoring data back to the monitoring module, and respectively analyzing the blood pressure monitoring data and the blood oxygen monitoring data to obtain trend contrast indexes and stability indexes corresponding to each monitoring data; the blood pumping regulating module is used for acquiring regulating indexes corresponding to the two monitoring data respectively according to trend contrast indexes and stability indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data respectively; and regulating the blood pumping volume by utilizing the regulating indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data. The application can more accurately regulate the blood pumping quantity, realizes automatic regulation of the blood pumping quantity, and can reduce errors and time delay when the blood pumping quantity is regulated manually.
Description
Technical Field
The application relates to the technical field of medical equipment, in particular to an intelligent left ventricle auxiliary system.
Background
The ventricular assist system is a novel product, is different from the traditional ventricular assist device or the heart blood pump, is mainly used for supporting the heart of a patient in the operation process, has the main advantages that the operation of opening the chest is not needed, and is usually carried out by a minimally invasive mode such as puncturing or cutting the femoral artery and the like, so that the operation risk is greatly reduced. It can maintain vital signs of patients with severe heart failure, or assist heart function in high risk surgery, reducing surgery risk.
The existing support to the heart of the patient during the operation, the operator needs to monitor each item of data of the patient in real time during the operation and then let the equipment operator manually adjust the pumping blood volume, so that the operator can have delay and error risks for transmitting the information to the equipment operator after observing the information, meanwhile, the existing monitoring is to adjust the pumping blood volume based on the difference value of the blood pressure, the blood oxygen content and the corresponding standard value, the pumping blood volume is not accurately adjusted by only using the difference value as the standard, and the influence of the adjusting amplitude of the pumping blood volume on the patient is not paid attention to.
Disclosure of Invention
In order to solve the technical problems, the application aims to provide an intelligent left ventricle auxiliary system, which adopts the following technical scheme:
one embodiment of the present application provides an intelligent left ventricular assist system: the system comprises a data detection module, a monitoring module and a blood pumping adjustment module;
the data detection module is used for collecting blood pressure monitoring data and blood oxygen monitoring data of a patient during operation; feeding back the blood pressure monitoring data and the blood oxygen monitoring data to a monitoring module;
the monitoring module is used for respectively analyzing the blood pressure monitoring data and the blood oxygen monitoring data to obtain trend contrast indexes and stability indexes corresponding to each monitoring data;
the blood pumping regulating module is used for acquiring regulating indexes corresponding to the two monitoring data respectively according to trend contrast indexes and stability indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data respectively; and regulating the blood pumping volume by utilizing the regulating indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data.
Preferably, the method for acquiring blood pressure monitoring data and blood oxygen monitoring data of a patient during surgery comprises:
setting a preset duration, and collecting blood pressure monitoring data and blood oxygen monitoring data according to a time sequence, wherein the sampling frequency is a preset frequency; and the collection end time of each monitoring data is the current time, and the collection duration is the preset duration.
Preferably, before the trend contrast index and the stability index corresponding to each monitoring data are obtained, the method further comprises:
acquiring blood pressure historical monitoring data and blood oxygen historical monitoring data respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data according to preset time length; the blood pressure history monitoring data and the blood oxygen history monitoring data are data collected by a patient before operation.
Preferably, the obtaining a trend contrast index corresponding to each monitoring data includes:
and calculating the pearson correlation coefficient of any monitoring data and the corresponding historical monitoring data, and normalizing to obtain trend comparison indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data.
Preferably, the stability index comprises:
and calculating the range and variance of any monitoring data, solving the sum of the range and the variance, and normalizing to obtain the stability index corresponding to the blood pressure monitoring data and the blood oxygen monitoring data respectively.
Preferably, the calculation formula of the adjustment index is:
wherein TJ i Representing an adjustment index corresponding to the ith monitoring data; q (Q) i Representing trend contrast indexes corresponding to the ith monitoring data; w (W) i Representing a stability index corresponding to the ith monitoring data; alpha and beta are weight coefficients respectively, and alpha is smaller than beta; exp []An exponential function based on a natural constant e is represented.
Preferably, the blood pumping amount is adjusted by using the adjustment indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data, including:
averaging the adjustment indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data to obtain an average adjustment index at the current moment;
if the blood pressure monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold value, the blood pumping amount is regulated in a rising way according to the first regulation amplitude until the blood pumping amount exceeds the maximum flow;
if the blood pressure monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is greater than the preset threshold, the blood pumping amount is regulated in a rising way according to the second regulation amplitude until the blood pumping amount exceeds the maximum flow;
if the blood pressure monitoring data at the current moment is higher than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold, reducing and regulating the blood pumping amount according to the first regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping amount is lower than the minimum flow;
if the blood pressure monitoring data at the current moment is higher than the corresponding standard range and the average regulation index is greater than the preset threshold, reducing and regulating the blood pumping amount according to the second regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping amount is lower than the minimum flow;
if the blood oxygen monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold, the blood pumping amount is regulated in a rising way according to the first regulation amplitude until the blood pressure monitoring data exceeds the corresponding standard range or the blood pumping amount is higher than the maximum flow;
and if the blood oxygen monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is greater than the preset threshold, carrying out rising regulation on the blood pumping quantity according to the second regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping quantity is higher than the maximum flow.
Preferably, the intelligent left ventricular assist system further comprises a flow processing module for monitoring a real-time blood flow of the patient, and issuing an alarm if a difference between the real-time blood flow and a human standard blood flow is greater than a flow threshold.
The embodiment of the application has at least the following beneficial effects: the application can know the heart condition of the patient in the operation process by detecting the blood pressure monitoring data and the blood oxygen monitoring data of the patient in the operation process, can monitor the heart function of the patient in real time, and provides a basis for the left ventricle auxiliary system to regulate the blood pumping amount; meanwhile, the collected blood pressure monitoring data and blood oxygen monitoring data are fed back to a monitoring module for analysis, and a trend comparison index and a stability index corresponding to each monitoring data are obtained, wherein the trend comparison index can reflect the similarity of the change trend of the blood pressure monitoring data and the blood oxygen monitoring data in a period of time compared with the historical data of a preoperative patient, and the blood pressure and blood oxygen information of the preoperative patient can be brought in through the trend comparison index, so that the blood pumping volume can be regulated more accurately; the stability index can reflect the stability of the change of blood pressure detection data and blood oxygen monitoring data of a patient in operation, the regulation index is obtained according to the stability index and the trend comparison index, the stability and trend of blood pressure and blood oxygen in a period of time are analyzed, the blood pumping quantity can be regulated more accurately and stably, meanwhile, the automatic regulation of the blood pumping quantity is realized, and the error and time delay when the blood pumping quantity is regulated manually can be reduced.
Drawings
In order to more clearly illustrate the embodiments of the application or the technical solutions and advantages of the prior art, the following description will briefly explain the drawings used in the embodiments or the description of the prior art, and it is obvious that the drawings in the following description are only some embodiments of the application, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
FIG. 1 is a system block diagram of an intelligent left ventricular assist system according to an embodiment of the present application;
FIG. 2 is a schematic view of a catheter according to an embodiment of the present application;
fig. 3 is a schematic view of a catheter according to an embodiment of the present application.
Detailed Description
In order to further describe the technical means and effects adopted by the present application to achieve the preset purpose, the following detailed description refers to the specific implementation, structure, characteristics and effects of an intelligent left ventricle auxiliary system according to the present application with reference to the accompanying drawings and the preferred embodiments. In the following description, different "one embodiment" or "another embodiment" means that the embodiments are not necessarily the same. Furthermore, the particular features, structures, or characteristics of one or more embodiments may be combined in any suitable manner.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.
The following specifically describes a specific scheme of an intelligent left ventricular assist system provided by the present application with reference to the accompanying drawings.
Examples:
the main application scene of the application is as follows: in the operation of a patient, various data of the patient need to be monitored to ensure that the operation of the patient is normally performed, and meanwhile, the heart of the patient needs to be supported to ensure that the blood pressure and the blood oxygen of the patient are ensured to be in a normal range, so that the blood pumping amount needs to be regulated according to the blood pressure and the blood oxygen content of the patient in the operation, and the blood pressure and the blood oxygen of the patient are always kept in the normal range in the operation.
Referring to fig. 1, a system block diagram of an intelligent left ventricle auxiliary system provided by an embodiment of the present application is shown, the system includes a data detection module, a monitoring module, a blood pumping adjustment module and a flow processing module, specifically:
the data detection module is used for collecting blood pressure monitoring data and blood oxygen monitoring data of a patient during operation; and feeding back the blood pressure monitoring data and the blood oxygen monitoring data to a monitoring module.
In an operating room, the heart of some patients needs to be maintained by using a maintenance device to ensure the health state of the patients in operation, and blood pressure and blood oxygen are important indexes, so that the changes of the blood pressure and the blood oxygen need to be monitored in real time, and then the subsequent analysis is carried out according to the changes of the blood pressure and the blood oxygen to obtain the regulation of the blood pumping volume.
Specifically, when acquiring blood pressure monitoring data and blood oxygen monitoring data, if only the current time data is acquired, the data is insufficient to analyze the change trend of blood pressure and blood oxygen, so that the blood oxygen and blood pressure monitoring data in a period of time need to be acquired in time sequence; further, the blood pressure monitoring data and the blood oxygen monitoring data are collected according to the time sequence, when the data are collected, the sampling frequency is the preset sampling frequency f, each monitoring data is collected according to the preset time length, for example, after the blood pressure monitoring data and the blood oxygen monitoring data of the first preset time length are collected, the blood pressure monitoring data and the blood oxygen monitoring data of the second preset time length are collected, and the end time of the completion of the collection of the monitoring data of each preset time length is the current time.
When blood pressure monitoring data and blood oxygen monitoring data of each preset time period are collected, a connector provided with a blood pressure sensor and a blood oxygen sensor in a ventricular assist system is connected to the finger or the earlobe of a patient, and then the data are collected through the blood pressure sensor and the blood oxygen sensor.
So far, blood pressure monitoring data and blood oxygen monitoring data in preset time periods can be obtained, wherein the blood pressure monitoring data in each preset time period is a data set, and the blood oxygen monitoring data in each preset time period is a data set.
The monitoring module is used for respectively analyzing the blood pressure monitoring data and the blood oxygen monitoring data to obtain trend contrast indexes and stability indexes corresponding to each monitoring data.
After the data detection module collects the blood pressure monitoring data and the blood oxygen monitoring data, the blood pressure monitoring data and the blood oxygen monitoring data need to be fed back to the monitoring module for subsequent analysis; the analysis of blood pressure monitoring data and blood oxygen monitoring data of a patient cannot be compared with only standard ranges of the two data, which causes errors in adjustment, and thus further analysis of the two monitoring data is required.
Further, acquiring historical data before operation of a patient, wherein the acquisition mode is the same as that of acquiring blood pressure monitoring data and blood oxygen monitoring data in operation of the patient, and acquiring the blood pressure historical monitoring data and the blood oxygen historical monitoring data respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data according to preset time length; the blood pressure history monitoring data and the blood oxygen history monitoring data are data collected by a patient before operation.
And then, obtaining trend comparison indexes of each monitoring data, specifically, calculating the pearson correlation coefficient of any one monitoring data and the corresponding historical monitoring data, normalizing the pearson correlation coefficient to ensure that the value of the pearson correlation coefficient is between 0 and 1, and obtaining the trend comparison indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data. The pearson correlation coefficient is widely used for measuring the degree of correlation between two variables, and the larger the value is, the more relevant the change trend between the two variables is, and the smaller the value is, the more irrelevant the change trend between the two variables is.
The blood pressure monitoring system has the advantages that the comparison trend indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data can be obtained, the change conditions of the blood pressure and the blood oxygen of a patient before and during operation can be compared, the information of the patient before operation is brought into analysis, more information is obtained, and the blood pumping amount is accurately regulated.
Meanwhile, the stability of blood pressure monitoring data and blood oxygen monitoring data in preset time length, namely volatility, is required to be analyzed, when the condition of a patient is healthy, the stability of the data is definitely higher, specifically, the range and variance of any monitoring data are calculated, the sum of the range and the variance is calculated, and normalization is carried out, so that the stability indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data respectively are obtained.
Thus, trend comparison indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data can be obtained, and stability indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data can be obtained.
The blood pumping regulating module is used for acquiring regulating indexes corresponding to the two monitoring data respectively according to trend contrast indexes and stability indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data respectively; and regulating the blood pumping volume by utilizing the regulating indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data.
In pumping the heart, the pump is required to extend through a catheter into the left ventricle, where the catheter is shown in fig. 2, where the flow sensor, pump, is located at the tip of the catheter, and where the catheter also has a developing ring. The catheter is positioned in the ventricle as shown in fig. 3. After the catheter has passed through the aorta into the left ventricle, the distal-most flow sensor is positioned in the left ventricle and the proximal flow sensor and pump are positioned in the aorta.
The control of the pump for pumping blood is to control the rotation speed of the motor in the module, drive the impeller at the head end of the conduit to rotate through the transmission device inside the conduit, calculate the theoretical blood pumping volume, and combine the real-time detection value of the flow sensor at the head end of the conduit to achieve the purpose of rapidly and accurately controlling the blood pumping volume.
After trend comparison indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data are obtained, respectively, and stability indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data are obtained, the trend comparison indexes and the stability indexes of each monitoring data are required to be comprehensively analyzed to obtain adjustment indexes of the blood pressure monitoring data and the blood oxygen monitoring data. The calculation formula of the adjustment index is specifically as follows:
wherein TJ i Representing an adjustment index corresponding to the ith monitoring data; q (Q) i Representing trend contrast indexes corresponding to the ith monitoring data; w (W) i Representing a stability index corresponding to the ith monitoring data; alpha and beta are weight coefficients respectively, wherein alpha is smaller than beta, and preferably, the value of alpha is 0.1, and the index of beta is 0.9; exp []An exponential function based on a natural constant e is represented.
It should be noted that, since the preoperative blood pressure and blood oxygen data of the patient are not necessarily healthy, but a certain amount of reference is needed to be made on the preoperative blood pressure and blood oxygen data of the patient, the trend is given a smaller weight than the comparative index, and the stability index is given a higher weight; in addition, TJ i The larger the value of (c) is, the closer the change of the monitoring data is to the change of the index in the patient health state, and the smaller the adjustment amplitude is required to fully ensure the health state in the patient operation when the blood pumping amount is adjusted.
The calculation modes of the regulation indexes of each monitoring data are the same, so that the regulation indexes of the blood pressure monitoring data and the regulation indexes of the blood oxygen monitoring data can be obtained, and the regulation indexes corresponding to the blood pressure monitoring data and the regulation indexes corresponding to the blood oxygen monitoring data are further averaged to obtain the average regulation indexes at the current moment.
The specific regulation step is that if the blood pressure monitoring data and the blood oxygen monitoring data at the current moment are in the corresponding standard ranges, the blood pumping quantity is not regulated;
if the blood pressure monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold value, carrying out rising regulation on the blood pumping amount according to the first regulation amplitude until the blood pumping amount exceeds the maximum flow, and stopping regulation;
if the blood pressure monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is greater than the preset threshold, the blood pumping amount is regulated in a rising way according to the second regulation amplitude until the blood pumping amount exceeds the maximum flow, and the regulation is stopped;
if the blood pressure monitoring data at the current moment is higher than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold, reducing and regulating the blood pumping amount according to the first regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping amount is lower than the minimum flow, and stopping regulating;
if the blood pressure monitoring data at the current moment is higher than the corresponding standard range and the average regulation index is greater than the preset threshold, reducing and regulating the blood pumping amount according to the second regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping amount is lower than the minimum flow, and stopping regulating;
if the blood oxygen monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold, the blood pumping quantity is regulated in a rising mode according to the first regulation amplitude until the blood pressure monitoring data exceeds the corresponding standard range or the blood pumping quantity is higher than the maximum flow, and the regulation is stopped;
if the blood oxygen monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is greater than the preset threshold, carrying out rising regulation on the blood pumping amount according to the second regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping amount is higher than the maximum flow, and stopping regulation;
the blood oxygen amount is generally not supersaturated for the patient. After the regulation of the blood volume of the pump is stopped, if the blood pressure monitoring data and the blood oxygen monitoring data still cannot reach the corresponding standard ranges, an alarm is sent out at the moment to remind doctors of intervention, if the blood pressure is too high, corresponding medicines need to be given, after the blood pressure is normal, the operation is continued, and if the blood oxygen is still too low, the patient can be possibly subjected to temporary oxygen inhalation to improve the blood oxygen volume.
Wherein the preset threshold value is 0.75 in the embodiment of the application, when the average adjustment index at the current moment is smaller than or equal to the preset threshold value, the patient's various data are not stable enough, the adjustment amplitude can be properly increased when the blood volume is adjusted, and when the average adjustment index at the current moment is larger than the preset threshold value, the patient's various data are stable, the adjustment amplitude can be properly reduced when the blood volume is adjustedThe first adjusting amplitude is larger than the second adjusting amplitude, namely the change amount of the primary pumping blood quantity adjusted by the first adjusting amplitude is larger than the change amount of the primary pumping blood quantity adjusted by the second adjusting amplitude, and the specific adjustment is the rotating speed of a motor in the pumping blood adjusting module, so that the first adjusting amplitude and the second adjusting amplitude can be the change amount of the motor power, and b is respectively in the embodiment of the application 1 And b 2 ，b 1 Greater than b 2 The motor drives the impeller at the head end of the catheter to rotate through the transmission device inside the catheter, so as to pump blood.
The intelligent left ventricle auxiliary system also comprises a flow processing module, wherein the flow processing module is used for measuring real-time blood flow in the operation of a patient through two sensors in the catheter, for example, when the blood pumping quantity is close to the maximum blood pumping quantity of a human body, and the blood oxygen and the blood pressure still cannot reach the standard range, the system is provided with a corresponding prompt at the moment, so that the operator is informed that the actual blood flow is close to the maximum at the moment, but the blood pressure and the blood pressure of the patient still do not reach the expected values; requiring manual intervention by medical personnel.
It should be noted that: the sequence of the embodiments of the present application is only for description, and does not represent the advantages and disadvantages of the embodiments. And the foregoing description has been directed to specific embodiments of this specification. In addition, the processes depicted in the accompanying figures do not necessarily require the particular order shown, or sequential order, to achieve desirable results. In some embodiments, multitasking and parallel processing are also possible or may be advantageous.
In this specification, each embodiment is described in a progressive manner, and identical and similar parts of each embodiment are all referred to each other, and each embodiment mainly describes differences from other embodiments.
The foregoing description of the preferred embodiments of the application is not intended to limit the application to the precise form disclosed, and any such modifications, equivalents, and alternatives falling within the spirit and scope of the application are intended to be included within the scope of the application.
Claims (8)
1. An intelligent left ventricle auxiliary system is characterized by comprising a data detection module, a monitoring module and a blood pumping regulation module;
the data detection module is used for collecting blood pressure monitoring data and blood oxygen monitoring data of a patient during operation; feeding back the blood pressure monitoring data and the blood oxygen monitoring data to a monitoring module;
the monitoring module is used for respectively analyzing the blood pressure monitoring data and the blood oxygen monitoring data to obtain trend contrast indexes and stability indexes corresponding to each monitoring data;
the blood pumping regulating module is used for acquiring regulating indexes corresponding to the two monitoring data respectively according to trend contrast indexes and stability indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data respectively; and regulating the blood pumping volume by utilizing the regulating indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data.
2. The intelligent left ventricular assist system of claim 1, wherein the means for collecting intraoperative blood pressure monitoring data and blood oxygen monitoring data of the patient comprises:
setting a preset duration, and collecting blood pressure monitoring data and blood oxygen monitoring data according to a time sequence, wherein the sampling frequency is a preset frequency; and the collection end time of each monitoring data is the current time, and the collection duration is the preset duration.
3. The intelligent left ventricular assist system of claim 1, further comprising, prior to the obtaining trend contrast indicators and stability indicators for each monitored data:
acquiring blood pressure historical monitoring data and blood oxygen historical monitoring data respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data according to preset time length; the blood pressure history monitoring data and the blood oxygen history monitoring data are data collected by a patient before operation.
4. The intelligent left ventricular assist system of claim 1, wherein the obtaining obtains trend contrast indicators corresponding to each monitored data comprises:
and calculating the pearson correlation coefficient of any monitoring data and the corresponding historical monitoring data, and normalizing to obtain trend comparison indexes respectively corresponding to the blood pressure monitoring data and the blood oxygen monitoring data.
5. The intelligent left ventricular assist system of claim 1, wherein the stability indicator comprises:
and calculating the range and variance of any monitoring data, solving the sum of the range and the variance, and normalizing to obtain the stability index corresponding to the blood pressure monitoring data and the blood oxygen monitoring data respectively.
6. The intelligent left ventricular assist system of claim 1 wherein the adjustment index is calculated as:
wherein TJ i Representing an adjustment index corresponding to the ith monitoring data; q (Q) i Representing trend contrast indexes corresponding to the ith monitoring data; w (W) i Representing a stability index corresponding to the ith monitoring data; alpha and beta are weight coefficients respectively, and alpha is smaller than beta; exp []An exponential function based on a natural constant e is represented.
7. The intelligent left ventricular assist system of claim 1, wherein the adjusting the amount of blood pumped using the respective adjustment indicators of the blood pressure monitor data and the blood oxygen monitor data comprises:
averaging the adjustment indexes corresponding to the blood pressure monitoring data and the blood oxygen monitoring data to obtain an average adjustment index at the current moment;
if the blood pressure monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold value, the blood pumping amount is regulated in a rising way according to the first regulation amplitude until the blood pumping amount exceeds the maximum flow;
if the blood pressure monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is greater than the preset threshold, the blood pumping amount is regulated in a rising way according to the second regulation amplitude until the blood pumping amount exceeds the maximum flow;
if the blood pressure monitoring data at the current moment is higher than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold, reducing and regulating the blood pumping amount according to the first regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping amount is lower than the minimum flow;
if the blood pressure monitoring data at the current moment is higher than the corresponding standard range and the average regulation index is greater than the preset threshold, reducing and regulating the blood pumping amount according to the second regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping amount is lower than the minimum flow;
if the blood oxygen monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is smaller than or equal to the preset threshold, the blood pumping amount is regulated in a rising way according to the first regulation amplitude until the blood pressure monitoring data exceeds the corresponding standard range or the blood pumping amount is higher than the maximum flow;
and if the blood oxygen monitoring data at the current moment is lower than the corresponding standard range and the average regulation index is greater than the preset threshold, carrying out rising regulation on the blood pumping quantity according to the second regulation amplitude until the blood oxygen monitoring data exceeds the corresponding standard range or the blood pumping quantity is higher than the maximum flow.
8. The intelligent left ventricular assist system of claim 1 further comprising a flow processing module for monitoring a patient's real-time blood flow and issuing an alarm if the difference between the real-time blood flow and a human standard blood flow is greater than a flow threshold.
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030120164A1 (en) * | 2001-12-20 | 2003-06-26 | Ge Medical Systems Information Technologies, Inc. | Patient monitor and method with non-invasive cardiac output monitoring |
| US20070142923A1 (en) * | 2005-11-04 | 2007-06-21 | Ayre Peter J | Control systems for rotary blood pumps |
| CN204106676U (en) * | 2014-09-15 | 2015-01-21 | 王卫国 | A kind of hemo system with automatic Measure blood pressure function |
| US20160151553A1 (en) * | 2013-03-14 | 2016-06-02 | Yale University | Implantable heart pump controller |
| US20170239407A1 (en) * | 2014-05-29 | 2017-08-24 | St Vincent's Hospital Sydney Limited | Ventricular Assist Device Method And Apparatus |
| US20230082362A1 (en) * | 2021-09-09 | 2023-03-16 | Nanowear Inc. | Processes and methods to predict blood pressure |
| CN116370819A (en) * | 2023-04-18 | 2023-07-04 | 安徽通灵仿生科技有限公司 | Pump blood flow estimation method and device for ventricular assist device |
-
2023
- 2023-07-10 CN CN202310838702.6A patent/CN116870357B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030120164A1 (en) * | 2001-12-20 | 2003-06-26 | Ge Medical Systems Information Technologies, Inc. | Patient monitor and method with non-invasive cardiac output monitoring |
| US20070142923A1 (en) * | 2005-11-04 | 2007-06-21 | Ayre Peter J | Control systems for rotary blood pumps |
| US20160151553A1 (en) * | 2013-03-14 | 2016-06-02 | Yale University | Implantable heart pump controller |
| US20170239407A1 (en) * | 2014-05-29 | 2017-08-24 | St Vincent's Hospital Sydney Limited | Ventricular Assist Device Method And Apparatus |
| CN204106676U (en) * | 2014-09-15 | 2015-01-21 | 王卫国 | A kind of hemo system with automatic Measure blood pressure function |
| US20230082362A1 (en) * | 2021-09-09 | 2023-03-16 | Nanowear Inc. | Processes and methods to predict blood pressure |
| CN116370819A (en) * | 2023-04-18 | 2023-07-04 | 安徽通灵仿生科技有限公司 | Pump blood flow estimation method and device for ventricular assist device |
Non-Patent Citations (2)
| Title |
|---|
| 张涛 等: "心脏辅助与替代装置中血泵的控制及监测方法", 中国医疗器械杂志, vol. 37, no. 06, 30 November 2013 (2013-11-30), pages 432 - 436 * |
| 王宗涛 等: "一种左心室辅助装置流量控制系统的仿真实验", 中国医疗器械杂志, vol. 40, no. 02, 30 March 2016 (2016-03-30), pages 143 - 146 * |
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