CN116869643A - Pulse and pressure combined radio frequency ablation catheter - Google Patents
Pulse and pressure combined radio frequency ablation catheter Download PDFInfo
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- CN116869643A CN116869643A CN202310843416.9A CN202310843416A CN116869643A CN 116869643 A CN116869643 A CN 116869643A CN 202310843416 A CN202310843416 A CN 202310843416A CN 116869643 A CN116869643 A CN 116869643A
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- 238000007674 radiofrequency ablation Methods 0.000 title claims abstract description 50
- 238000002679 ablation Methods 0.000 claims abstract description 224
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- 230000005540 biological transmission Effects 0.000 claims description 26
- 238000001179 sorption measurement Methods 0.000 claims description 17
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- 230000033001 locomotion Effects 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 2
- 238000003763 carbonization Methods 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 238000002844 melting Methods 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 5
- 238000010438 heat treatment Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
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- 206010031264 Osteonecrosis Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
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- 230000008018 melting Effects 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 238000011297 radiofrequency ablation treatment Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
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Abstract
The invention relates to a radio frequency ablation catheter with combined action of pulse and pressure, which comprises a first electrode ablation part and a second electrode ablation part, wherein the first electrode ablation part and the second electrode ablation part are arranged in parallel, and the first electrode ablation part and the second electrode ablation part alternately act on tissues, so that carbonization damage to the tissues caused by overhigh temperature of any one electrode ablation part is avoided, and the pressure of any one electrode ablation part on the tissues can be regulated to ensure the hot-melting effect. The invention heats the tissue by the pulse and replaces the electrode ablation part with the spare electrode ablation part, thereby avoiding charring the tissue by the electrode ablation part with overhigh temperature.
Description
Technical Field
The invention relates to the technical field of radio frequency ablation, in particular to a radio frequency ablation catheter with combined action of pulse and pressure.
Background
The radio frequency ablation technology mainly depends on a radio frequency therapeutic instrument with ablation and cutting functions, and the therapeutic mechanism is mainly a thermal effect. When the radio frequency current flows through human tissue, the water molecules with polarity in the tissue move at high speed due to the rapid change of the electromagnetic field, heat is generated (i.e. internal heat effect), so that the water inside and outside the cell is evaporated, dried, condensed and shed so as to cause aseptic necrosis, thereby achieving the aim of treatment.
In the radio frequency ablation treatment, a commonly used instrument is a radio frequency ablation catheter, the radio frequency ablation catheter enters a blood vessel to reach a lesion part for ablation, high-frequency current is formed by moving under the action of a high-frequency electric field, simultaneously joule heat is generated, the temperature is rapidly increased, and the tissue near an electrode is denatured and inactivated, so that the aim of tissue ablation is fulfilled
The prior ablation catheter has the following technical defects: the temperature of the existing ablation catheter is high (60 ℃ -100 ℃), which is easy to cause carbonization of tissues around the electrode; however, the heating of the lesion tissue is insufficient, so that the hot melting effect is not achieved, and the treatment effect is poor due to overheating or insufficient heating of the tissue.
Disclosure of Invention
The invention designs a radio frequency ablation catheter with combined action of pulse and pressure, which solves at least one technical problem proposed by the background technology.
In order to solve the technical problems, the invention adopts the following scheme:
in a first aspect, the present invention provides a pulsed and pressure combined action radiofrequency ablation catheter comprising:
a first electrode ablation portion;
the first electrode ablation part and the second electrode ablation part are arranged in parallel;
and, the radiofrequency ablation catheter has a first state and a second state;
in the first state, the first electrode ablation part stretches out and performs radio frequency ablation operation, and the second electrode ablation part contracts to the rear of the first electrode ablation part;
in the second state, the second electrode ablation portion extends out and performs radio frequency ablation operation, and the first electrode ablation portion contracts to the rear of the second electrode ablation portion.
Preferably, the first electrode ablation portion and the second electrode ablation portion are configured to be capable of horizontal reverse motion.
Preferentially, the radiofrequency ablation catheter further comprises:
the shell is a cavity with an opening at one end;
the first electrode ablation part and the second electrode ablation part are positioned in the shell;
when the first electrode ablation part extends out of the shell, the second electrode ablation part is contracted into the shell, or when the second electrode ablation part extends out of the shell, the first electrode ablation part is contracted into the shell.
Preferentially, the radiofrequency ablation catheter further comprises:
a transmission mechanism, the transmission mechanism comprising:
the first transmission rack is arranged at the side part of the first electrode ablation part;
and a second drive rack arranged at the side part of the second electrode ablation part;
further comprises:
and the transmission gear is meshed with the first transmission rack and the second transmission rack respectively and drives the first electrode ablation part and the second electrode ablation part to slide along opposite directions.
Preferentially, the radiofrequency ablation catheter further comprises:
a driving device, the driving device comprising:
a magnet fixed to an end of the first electrode ablation portion or an end of the second electrode ablation portion;
and the electromagnetic adsorption device can generate magnetic force and adsorb the magnet, and the first electrode ablation part or the second electrode ablation part is driven to move towards the direction of the electromagnetic adsorption device.
Preferably, the driving device further includes:
and one end part of the spring is connected with the electromagnetic adsorption device, and the other end part of the spring is connected with the magnet.
Preferentially, a first pressure sensor is arranged at the end part of the first electrode ablation part, and a second pressure sensor is arranged at the end part of the second electrode ablation part;
the first electrode ablation portion is provided with a first temperature sensor, and the second electrode ablation portion is provided with a second temperature sensor.
Preferably, opposite side parts of the first electrode ablation part and the second electrode ablation part are arranged to be matched with each other in a concave-convex structure.
Preferentially, a plurality of guide grooves are formed in the shell along the length direction, guide rods are arranged on the outer walls of the first electrode ablation part and the second electrode ablation part, and the guide rods can slide in the guide grooves.
In a second aspect, the present invention also provides a method for controlling a radiofrequency ablation catheter with combined action of pulses and pressure, comprising the steps of:
the first electrode ablation part executes ablation operation, the second electrode ablation part is positioned behind the first electrode ablation part for standby, the first temperature sensor monitors the temperature of the first electrode ablation part, and the first pressure sensor detects that the first electrode ablation part generates a pressure value to tissues;
when the temperature value output by the first temperature sensor is higher than a set value T1, starting the driving device to enable the high-temperature first electrode ablation part to move backwards for cooling, and simultaneously enabling the low-temperature second electrode ablation part to move forwards;
when the output value of the second pressure sensor of the second electrode ablation part reaches a preset value P1, the second electrode ablation part is started to execute ablation operation;
when the output temperature of a second temperature sensor of the second electrode ablation part is higher than T2, starting a driving device to reduce magnetic force so as to reset a spring, so that the first electrode ablation part moves forwards, the second electrode ablation part moves backwards, the value of a second pressure sensor is reduced to P2, the temperature T1 is more than the temperature T2, and the pressure P1 is more than the pressure P2;
when the output temperature of the second temperature sensor is higher than T1, the driving device closes the magnetic force, the spring enables the first electrode ablation part to extend out of the shell to contact with tissues, the tissues are heated again, and the second electrode ablation part returns to the shell to be cooled and waits for the next use.
The radiofrequency ablation catheter with the combined action of the pulse and the pressure has the following beneficial effects:
(1) According to the invention, the first electrode ablation part and the second electrode ablation part are arranged, so that the first electrode ablation part and the second electrode ablation part can alternately work, and carbonization of tissues by the electrode ablation part with overhigh temperature is avoided.
(2) The invention judges the contact degree of the electrode ablation part and the tissue by arranging the pressure sensor, thereby enabling the electrode ablation part to be in close contact with the tissue at low temperature and gradually separating the electrode ablation part from the tissue at high temperature, and taking into consideration the dual aims of avoiding carbonization and ensuring heating quality.
(3) The invention sets two temperatures, and can control the temperature by moving the electrode ablation part to reduce the contact area with the tissue at a lower safety temperature, and can control the temperature by changing the electrode ablation part at a higher temperature, thereby ensuring the heating quality and shortening the operation time.
Drawings
Fig. 1: the first working state schematic diagram of the radiofrequency ablation catheter with combined action of pulse and pressure is provided;
fig. 2: the second working state schematic diagram of the radiofrequency ablation catheter with the combined action of the pulse and the pressure is shown;
fig. 3: the third working state schematic diagram of the radiofrequency ablation catheter with combined action of pulse and pressure is provided;
fig. 4: the transmission structure of the first electrode ablation part is schematically shown in the invention;
fig. 5: the transmission structure of the second electrode ablation part is schematically shown in the invention;
fig. 6: in the invention, a first electrode ablation part and a second electrode ablation part are connected with a schematic diagram through a transmission structure;
fig. 7: in the invention, a first electrode ablation part and a second electrode ablation part are combined;
fig. 8: an explosion diagram of a combined structure of a first electrode ablation part and a second electrode ablation part in the invention;
reference numerals illustrate:
11-a housing; 12-cavity; 13-mounting brackets; 14-a guide groove; 21-a first electrode ablation portion; 211—a first guide bar; 212-a first bump; 22-a first pressure sensor; 23-a second electrode ablation portion; 231-a second guide bar; 232-a second bump; 24-a second pressure sensor; 31-electromagnetic adsorption device; 32-a magnet; 33-a spring; 4-a transmission gear; 41-a first drive rack; 42-a second drive rack; 43-a first spindle carrier; 44-a second spindle bracket; 45-mounting cavity.
Detailed Description
The invention is further described with reference to fig. 1 to 8:
as shown in fig. 1 to 3, an embodiment of the present invention provides a radiofrequency ablation catheter with combined action of pulse and pressure, the radiofrequency ablation catheter includes a first electrode ablation portion 21 and a second electrode ablation portion 23, and the first electrode ablation portion 21 and the second electrode ablation portion 23 are arranged in parallel;
the radiofrequency ablation catheter has a first state and a second state;
in the first state, the first electrode ablation portion 21 is extended and performs a radio frequency ablation operation, and the second electrode ablation portion 23 is contracted to the rear of the first electrode ablation portion 21;
in the second state, the second electrode ablation portion 23 is extended and radio frequency ablation is performed, and the first electrode ablation portion 21 is contracted to the rear of the second electrode ablation portion 23.
By providing the first electrode ablation portion 21 and the second electrode ablation portion 23, the first electrode ablation portion 21 and the second electrode ablation portion 23 can alternately operate, that is, the first electrode ablation portion 21 is stretched out and performs radio frequency ablation operation in the first state, and when the temperature of the first electrode ablation portion 21 is too high, the second state operation, that is, the first electrode ablation portion 21 is contracted, the second electrode ablation portion 23 is stretched out and performs radio frequency ablation operation, and at this time, the first electrode ablation portion 21 is cooled. When the working temperature of the second electrode ablation part 23 is too high, the second electrode ablation part 23 contracts to cool, the first electrode ablation part 21 stretches out and carries out radio frequency ablation working, and thus the alternating working in the first state and the second state avoids charring of the tissue by the electrode ablation part with too high temperature.
On the basis of the above embodiment, the embodiment of the present invention further provides that the first electrode ablation portion 21 and the second electrode ablation portion 23 are configured to be capable of horizontal reverse movement. By moving the first electrode ablation portion 21 and the second electrode ablation portion 23 in the horizontal direction, the alternating operation in the first state and the second state is achieved.
In one embodiment, the radiofrequency ablation catheter further includes a housing 11, the assembly of the first electrode ablation portion 21 and the second electrode ablation portion 23 is achieved through the housing 11, and the housing 11 is a cavity with an opening at one end; the first electrode ablation portion 21 and the second electrode ablation portion 23 are located in the housing 11;
when the first electrode ablation part 21 extends out of the housing 1, the second electrode ablation part 23 is retracted into the housing, or when the second electrode ablation part 23 extends out of the housing 1, the first electrode ablation part 23 is retracted into the housing. That is, the first electrode ablation portion 21 and the second electrode ablation portion 23 alternately extend out of the housing 1 to realize the alternate operation in the first state and the second state.
In one embodiment, as shown in fig. 4 and 5, the radiofrequency ablation catheter further includes a transmission mechanism, and the transmission mechanism includes a first transmission rack 41 disposed on a side portion of the first electrode ablation portion 21; and a second drive rack 42 provided on a side of the second electrode ablation portion 23; and a transmission gear 4, wherein the transmission gear 4 is respectively meshed with the first transmission rack 41 and the second transmission rack 42, and drives the first electrode ablation part 21 and the second electrode ablation part 23 to slide along opposite directions. Specifically, the upper and lower sides of the drive gear 4 are respectively engaged with the first drive rack 41 and the second drive rack 42.
Further, as shown in fig. 6, the first electrode ablation portion 21 is provided with a first bump 212, the second electrode ablation portion 23 is provided with a second bump 232, the first driving rack 41 is mounted on the first bump 212, and the second driving rack 42 is mounted on the second bump 232; a mounting cavity 45 is formed between the second bump 232 and the first bump 212, the transmission gear 4 is mounted in the mounting cavity 45, one end of a rotating shaft of the transmission gear 4 is connected with the inner top of the shell 11 through a first rotating shaft bracket 43, and the other end of the rotating shaft of the transmission gear 4 is connected with the inner bottom of the shell 11 through a second rotating shaft bracket 44. The above-described connection structure of the first and second rotation shaft brackets 43 and 44 may enable the transmission gear 4 to be independently located in the installation cavity and freely rotated.
In one embodiment, the radiofrequency ablation catheter further comprises a driving device, the driving device comprises a magnet 32 and an electromagnetic adsorption device 31, and the magnet 32 is fixed at the end of the first electrode ablation part 21 or the end of the second electrode ablation part 23; the electromagnetic adsorption device 31 can generate magnetic force and adsorb the magnet 32, and drive the first electrode ablation portion 21 or the second electrode ablation portion 23 to move in the direction of the electromagnetic adsorption device 31.
Specifically, the electromagnetic adsorption device 31 is mounted in the cavity 12 of the housing 11 through the mounting bracket 12, and the magnet 32 is mounted at the end of the first electrode ablation portion 21 or the second electrode ablation portion 23, and the electromagnetic adsorption device 31 adsorbs the magnet 32 by generating magnetic force, so that the first electrode ablation portion 21 or the second electrode ablation portion 23 moves toward the electromagnetic adsorption device 31.
In one embodiment, the driving device further includes a spring 33, one end of the spring 33 is connected to the electromagnetic adsorption device 31, and the other end of the spring 33 is connected to the magnet 32.
In the above embodiment, the electromagnetic adsorption device 31 generates a magnetic force with controllable magnitude, so that the displacement of the first electrode ablation portion 21 or the second electrode ablation portion 23 is controllable. The electromagnetic adsorption device 31 generates magnetic force and elastic restoring force of the spring 33 to realize horizontal reciprocating movement of the first electrode ablation portion 21 and the second electrode ablation portion 23.
In one embodiment, the housing 11 is provided with a plurality of guide grooves 14 along the length direction, and the outer walls of the first electrode ablation portion 21 and the second electrode ablation portion 23 are provided with guide rods, and the guide rods can slide in the guide grooves 14. Specifically, the outer wall of the first electrode ablation portion 21 is provided with a first guide bar 211, and the first guide bar 211 can slide in one guide groove 14; the second electrode ablation part 23 is provided with a second guide bar 231 on the outer wall, and the second guide bar 231 is slidable in the other guide groove 14.
In an embodiment, as shown in fig. 7 and 8, opposite side portions of the first electrode ablation portion 21 and the second electrode ablation portion 23 are configured to have concave-convex structures, and the side portions of the two are configured to have concave-convex structures, so that contact positions of the first electrode ablation portion 21 and the second electrode ablation portion 23 with body tissues can be ensured to be substantially the same, thereby improving quality and efficiency of ablation operation.
In one embodiment, the end of the first electrode ablation part 21 is provided with a first pressure sensor 22, and the end of the second electrode ablation part 23 is provided with a second pressure sensor 24;
the first electrode ablation part 21 is provided with a first temperature sensor, and the second electrode ablation part 23 is provided with a second temperature sensor.
The working temperatures of the first electrode ablation part 21 and the second electrode ablation part 23 are monitored in real time by arranging a first temperature sensor and a second temperature sensor, and the contact tightness between the first electrode ablation part 21 and the second electrode ablation part 23 and the body tissue is monitored in real time by arranging a first pressure sensor 22 and a second pressure sensor 24.
Based on the above embodiment, the embodiment of the present invention further provides a control method of a radiofrequency ablation catheter with combined action of pulse and pressure, including the following steps:
the first electrode ablation part 21 executes ablation operation, the second electrode ablation part 23 is positioned behind the first electrode ablation part 21 for standby, the first temperature sensor monitors the temperature of the first electrode ablation part 21, and the first pressure sensor detects that the first electrode ablation part 21 generates a pressure value to the tissue;
when the temperature value output by the first temperature sensor is higher than a set value T1, starting the driving device, so that the high-temperature first electrode ablation part 21 moves backwards to cool, and the low-temperature second electrode ablation part 23 moves forwards; the alternating operation is realized, and the carbonization damage to the tissue caused by the overhigh temperature is avoided.
When the output value of the second pressure sensor of the second electrode ablation part 23 reaches a preset value P1, the second electrode ablation part 23 is started to execute ablation operation;
when the output temperature of the second temperature sensor of the second electrode ablation part 23 is higher than T2, the driving device is started to reduce the magnetic force so that the spring 33 is reset, the first electrode ablation part 21 moves forwards, the second electrode ablation part 23 moves backwards, the value of the second pressure sensor is reduced to P2, the temperature T1 is higher than the temperature T2, and the pressure P1 is higher than the pressure P2; so that the second electrode ablation part 23 with higher temperature keeps a certain working distance with the organism tissue, and carbonization damage to the tissue caused by overhigh temperature is avoided.
When the output temperature of the second temperature sensor is higher than T1, the driving device turns off the magnetic force, the spring enables the first electrode ablation part 21 to extend out of the shell to contact with the tissue, the tissue is heated again, and the second electrode ablation part 23 returns to the shell to be cooled, and the next use is waited.
The invention has been described above by way of example with reference to the accompanying drawings, it is clear that the implementation of the invention is not limited to the above-described manner, but it is within the scope of the invention to apply the inventive concept and technical solution to other situations as long as various improvements made by the inventive concept and technical solution are adopted or without any improvement.
Claims (10)
1. A radio frequency ablation catheter with combined action of pulse and pressure, characterized in that: the radiofrequency ablation catheter includes:
a first electrode ablation unit (21);
a second electrode ablation unit (23), wherein the first electrode ablation unit (21) and the second electrode ablation unit (23) are arranged in parallel;
and, the radiofrequency ablation catheter has a first state and a second state;
in the first state, the first electrode ablation part (21) stretches out and performs radio frequency ablation operation, and the second electrode ablation part (23) is contracted to the rear of the first electrode ablation part (21);
in the second state, the second electrode ablation part (23) stretches out and performs radio frequency ablation operation, and the first electrode ablation part (21) is contracted to the rear of the second electrode ablation part (23).
2. The pulse and pressure combined radio frequency ablation catheter of claim 1, wherein: the first electrode ablation portion (21) and the second electrode ablation portion (23) are configured to be capable of horizontal reverse movement.
3. The pulse and pressure combined radio frequency ablation catheter of claim 1, wherein: the radiofrequency ablation catheter further comprises:
a housing (11), wherein the housing (11) is a cavity with an opening at one end;
the first electrode ablation part (21) and the second electrode ablation part (23) are positioned in the shell (11);
when the first electrode ablation part (21) stretches out of the shell (1), the second electrode ablation part (23) contracts into the shell, or when the second electrode ablation part (23) stretches out of the shell (1), the first electrode ablation part (23) retracts into the shell.
4. The pulse and pressure combined radio frequency ablation catheter of claim 1, wherein: the radiofrequency ablation catheter further comprises:
a transmission mechanism, the transmission mechanism comprising:
a first drive rack (41) provided on the side of the first electrode ablation unit (21);
and a second drive rack (42) provided on the side of the second electrode ablation section (23);
further comprises:
and the transmission gear (4) is meshed with the first transmission rack (41) and the second transmission rack (42) respectively, and drives the first electrode ablation part (21) and the second electrode ablation part (23) to slide along opposite directions.
5. The pulse and pressure combined radio frequency ablation catheter of claim 1, wherein: the radiofrequency ablation catheter further comprises:
a driving device, the driving device comprising:
a magnet (32), wherein the magnet (32) is fixed to an end of the first electrode ablation part (21) or an end of the second electrode ablation part (23);
and an electromagnetic adsorption device (31), wherein the electromagnetic adsorption device (31) can generate magnetic force and adsorb the magnet (32), and the first electrode ablation part (21) or the second electrode ablation part (23) is driven to move towards the direction of the electromagnetic adsorption device (31).
6. The pulse and pressure combined radio frequency ablation catheter of claim 1, wherein: the driving device further includes:
and a spring (33), wherein one end of the spring (33) is connected to the electromagnetic adsorption device (31), and the other end of the spring (33) is connected to the magnet (32).
7. The radiofrequency ablation catheter with combined action of pulse and pressure according to claim 1, characterized in that the end of the first electrode ablation part (21) is provided with a first pressure sensor (22), and the end of the second electrode ablation part (23) is provided with a second pressure sensor (24);
the first electrode ablation part (21) is provided with a first temperature sensor, and the second electrode ablation part (23) is provided with a second temperature sensor.
8. A pulsed, pressure-combined, radiofrequency ablation catheter as recited in claim 3, wherein: the shell (11) is provided with a plurality of guide grooves (14) along the length direction, the outer walls of the first electrode ablation part (21) and the second electrode ablation part (23) are respectively provided with a guide rod, and the guide rods can slide in the guide grooves (14).
9. The radiofrequency ablation catheter acting in combination with pulse and pressure according to any one of claims 1-8, characterized in that the opposite sides of the first electrode ablation portion (21) and the second electrode ablation portion (23) are arranged to cooperate with each other in a concave-convex configuration.
10. A method of controlling a pulse and pressure combined radio frequency ablation catheter according to any of claims 1-9, comprising the steps of:
the first electrode ablation part (21) executes ablation operation, the second electrode ablation part (23) is positioned behind the first electrode ablation part (21) for standby, the first temperature sensor monitors the temperature of the first electrode ablation part (21), and the first pressure sensor detects the pressure value generated by the first electrode ablation part (21) on tissues;
when the temperature value output by the first temperature sensor is higher than a set value T1, starting the driving device to enable the high-temperature first electrode ablation part (21) to move backwards for cooling, and simultaneously enabling the low-temperature second electrode ablation part (23) to move forwards;
when the output value of a second pressure sensor of the second electrode ablation part (23) reaches a preset value P1, starting the second electrode ablation part (23) to execute ablation operation;
when the output temperature of a second temperature sensor of the second electrode ablation part (23) is higher than T2, a driving device is started to reduce magnetic force so that a spring (33) is reset, the first electrode ablation part (21) moves forwards, the second electrode ablation part (23) moves backwards, and the value of the second pressure sensor is reduced to P2; and, temperature T1 > temperature T2, pressure P1 > pressure P2;
when the output temperature of the second temperature sensor is higher than T1, the driving device closes the magnetic force, the spring enables the first electrode ablation part (21) to extend out of the shell to contact with tissues, the tissues are heated again, and the second electrode ablation part (23) returns to the shell to be cooled, and the next use is waited.
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CN202310843416.9A CN116869643A (en) | 2023-07-10 | 2023-07-10 | Pulse and pressure combined radio frequency ablation catheter |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN117694998A (en) * | 2024-02-05 | 2024-03-15 | 杭州科嘉生物技术有限公司 | Circulation cooling type ablation device |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN117694998A (en) * | 2024-02-05 | 2024-03-15 | 杭州科嘉生物技术有限公司 | Circulation cooling type ablation device |
CN117694998B (en) * | 2024-02-05 | 2024-04-19 | 杭州科嘉生物技术有限公司 | Circulation cooling type ablation device |
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