CN116829061A

CN116829061A - Monitoring device and method for determining accuracy of pulse pressure variation degree

Info

Publication number: CN116829061A
Application number: CN202180087001.2A
Authority: CN
Inventors: 袁全; 王澄; 吴学磊; 袁微微; 李漾菲; 邓卓敏
Original assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Current assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date: 2020-12-25
Filing date: 2021-10-21
Publication date: 2023-09-29
Also published as: WO2022134803A1

Abstract

A monitoring device and method for determining accuracy of pulse pressure variability, the monitoring device being for monitoring vital sign parameters of a target subject, comprising: a signal acquisition circuit (102) for acquiring vital sign signals of a target object; a processor (101) for processing the vital sign signals to obtain vital sign parameters of the target subject; the processor (101) is further configured to: processing the data of vital sign parameters to obtain the pulse pressure variation degree of the target object; acquiring a plurality of associated parameters of a target object representing the accuracy of the pulse pressure variation; based on a plurality of associated parameters, the accuracy of the pulse pressure variation degree is determined, so that the possibility that a user misjudges the physiological state of a patient due to inaccurate pulse pressure variation degree is reduced.

Description

Monitoring device and method for determining accuracy of pulse pressure variation degree

Description

Technical Field

The present invention relates generally to the field of medical devices, and more particularly to a monitoring device and method of determining the accuracy of pulse pressure variability.

Background

Fluid responsiveness refers to the ability to increase Cardiac Output (CO) after a certain amount of fluid is infused in a short period of time, and fluid replacement can increase CO significantly when the patient's preload is in the rising segment of the Frank-Starling curve. For critically ill patients, fluid responsiveness is an extremely important link in hemodynamic assessment, which is the basis for fluid management.

Clinically, pulse pressure variability (pulse pressure variation, PPV for short) can be used to assess patient fluid responsiveness, guiding fluid management in mechanically ventilated patients. In particular, in ICU, most patients are mechanically ventilated and have invasive blood pressure (invasive blood pressure, IBP) monitoring, and PPV is more convenient to obtain. Academic studies have demonstrated that the value of PPV can be used to indicate whether a patient is fluid reactive.

Notably, PPV has certain preconditions for predicting fluid responsiveness of mechanically ventilated patients, which would otherwise lead to inaccurate calculations. At present, the PPV parameter is presented without an accuracy prompt, and the PPV value measured in a way of being out of condition may mislead the judgment of the patient capacity responsiveness by a doctor, cause wrong clinical decisions and influence the optimization of fluid management and the patient hemodynamic state.

Disclosure of Invention

The present invention has been made in order to solve at least one of the above problems. Specifically, an aspect of the present invention provides a monitoring device, including:

the signal acquisition circuit is used for acquiring vital sign signals of the target object;

a processor for processing the vital sign signals to obtain vital sign parameters of the target subject; the processor is further configured to:

Processing the data of the vital sign parameters to obtain the pulse pressure variation degree of the target object;

acquiring a plurality of associated parameters of the target object, which characterize the accuracy of the pulse pressure variation;

and determining the accuracy of the pulse pressure variation degree based on the plurality of associated parameters.

In yet another aspect, the present invention provides a monitoring device for monitoring vital sign parameters of a target subject, comprising:

processing the data of the vital sign parameters to obtain monitoring parameters for characterizing the volume responsiveness of the target object;

acquiring a plurality of associated parameters of the target object, which characterize the accuracy of the monitoring parameters;

based on the plurality of associated parameters, an accuracy of the monitored parameters is determined.

In yet another aspect, the present invention provides a monitoring device for monitoring vital sign parameters of a target subject, the monitoring device comprising:

acquiring associated features of the target object, which characterize the accuracy of the monitoring parameters;

and determining the accuracy of the monitoring parameters based on the correlation characteristics.

In another aspect, the present application also provides a method for determining accuracy of pulse pressure variability, the method comprising: acquiring vital sign parameters of a target object; processing the data of the vital sign parameters to obtain the pulse pressure variation degree of the target object; acquiring a plurality of associated parameters of the target object, which characterize the accuracy of the pulse pressure variation; and determining the accuracy of the pulse pressure variation degree based on the plurality of associated parameters.

According to the monitoring device and the method for determining the accuracy of the pulse pressure variation, the accuracy of the pulse pressure variation can be determined based on the plurality of associated parameters, so that the result of the accuracy of the pulse pressure variation is fed back to a user, the user can find out that the PPV value is wrong in time, the possibility that the user misjudges the physiological state of the patient due to an inaccurate PPV value is reduced, and meanwhile, clinical staff can be helped to correct the cause of the inaccurate PPV value in time, and the accuracy of PPV parameter monitoring is guaranteed, so that a doctor can be assisted in liquid management of the patient better.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed in the description of the embodiments will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present invention, and that other drawings may be obtained according to these drawings without inventive effort to a person skilled in the art.

FIG. 1 shows a schematic block diagram of a monitoring device in one embodiment of the invention;

FIG. 2 shows a schematic diagram of a display interface of a display in one embodiment of the invention;

FIG. 3 is a flow chart of a method of determining the accuracy of pulse pressure variability in one embodiment of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, exemplary embodiments according to the present invention will be described in detail with reference to the accompanying drawings. It should be apparent that the described embodiments are only some embodiments of the present invention and not all embodiments of the present invention, and it should be understood that the present invention is not limited by the example embodiments described herein. Based on the embodiments of the invention described in the present application, all other embodiments that a person skilled in the art would have without inventive effort shall fall within the scope of the invention.

In the following description, numerous specific details are set forth in order to provide a more thorough understanding of the present invention. It will be apparent, however, to one skilled in the art that the invention may be practiced without one or more of these details. In other instances, well-known features have not been described in detail in order to avoid obscuring the invention.

It should be understood that the present invention may be embodied in various forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof. As used herein, the term "and/or" includes any and all combinations of the associated listed items.

In view of the foregoing problems with monitoring devices, the present application provides a monitoring device for monitoring vital sign parameters of a target subject, comprising: the signal acquisition circuit is used for acquiring vital sign signals of the target object; the processor is used for processing the vital sign signals to obtain vital sign parameters of the target object; the processor is further configured to: processing the data of vital sign parameters to obtain the pulse pressure variation degree of the target object; acquiring a plurality of associated parameters of a target object representing the accuracy of the pulse pressure variation; the accuracy of the pulse pressure variability is determined based on the plurality of correlation parameters.

According to the monitoring equipment and the method for determining the accuracy of the pulse pressure variation, the accuracy of the pulse pressure variation can be determined based on a plurality of associated parameters, so that the result of the accuracy of the pulse pressure variation is fed back to a user, the user can find out that the PPV value is wrong in time, the possibility that the user misjudges the physiological state of the patient due to the inaccurate PPV value is reduced, and meanwhile, the method can help clinical staff correct the cause of the inaccurate PPV value in time, and therefore the accuracy of PPV parameter monitoring is guaranteed, and the liquid management of the patient by a doctor is facilitated to be better assisted.

In order to provide a thorough understanding of the present application, detailed structures will be presented in the following description in order to illustrate the technical solutions presented by the present application. Alternative embodiments of the application are described in detail below, however, the application may have other implementations in addition to these detailed descriptions. In particular, the monitoring device and the method for determining the accuracy of the pulse pressure variation degree of the present application will be described in detail with reference to the accompanying drawings. The features of the examples and embodiments described below may be combined with each other without conflict.

As an example, the monitoring device of the embodiment of the present application obtains the physiological parameters of the subject connected thereto, and the monitoring device of the present application may be a bedside monitor, a central station, a PC on which monitoring software is installed, or the like. The monitoring equipment can also be a breathing machine, a ward round machine and the like, and the breathing machine, the ward round machine and the like can acquire needed parameter information from a monitor or other information systems so as to judge the accuracy of the PPV. The following examples illustrate the application mainly using bedside monitors.

The monitoring device 100 may include one or more processors 101, one or more sensors 102, a display 103, a memory 104, a communication interface, and the like. These components are interconnected by a bus system and/or other forms of connection mechanisms (not shown). It should be noted that the components and configuration of the monitoring device 100 shown in fig. 1 are exemplary only and not limiting, as the monitoring device 100 may have other components and configurations as desired.

The monitoring device 100 has a separate housing with a sensor interface area on a housing panel in which a plurality of sensor interfaces are integrated for connection to external individual physiological parameter sensor accessories (not shown). The sensor is used for detecting a physiological parameter (herein also referred to as vital sign parameter) of a subject (i.e. a target subject) to which the monitoring device is connected, e.g. the physiological parameter comprises at least one of the following: blood pressure, respiration rate, heart rate, body temperature, pulse rate, blood oxygen saturation, cardiac output, end-tidal carbon dioxide, brain electricity, electrocardiogram, etc. In one example, the monitoring device may also be used to determine a pulse pressure variability of a subject to which the monitoring device is connected and output an electrical signal that characterizes the pulse pressure variability.

The monitoring device 100 further comprises a signal acquisition circuit 102, a front-end signal processing circuit (not shown), etc., corresponding to each physiological parameter. The signal acquisition circuit 102 is used for acquiring vital sign signals of a target object. The signal acquisition circuit 102 may be selected from an electrocardiograph circuit, a respiratory circuit, a body temperature circuit, an oximetry circuit, a noninvasive blood pressure circuit, an invasive blood pressure circuit, etc., and is electrically connected to the corresponding sensor interfaces, for electrically connecting to the sensor accessories corresponding to different physiological parameters, the output end of the signal acquisition circuit is coupled to a front-end signal processor, the communication port of the front-end signal processor is coupled to the processor 101, and the processor 101 is electrically connected to the external communication and power interface. The processor 101 may be configured to process the vital sign signals acquired by the signal acquisition circuit 102 to obtain vital sign parameters of the target subject.

The various physiological parameter measuring circuits can adopt a general circuit in the prior art, and the front-end signal processor is used for completing sampling and analog-to-digital conversion of the output signals of the signal acquisition circuit and outputting control signals to control the physiological signal measuring process. In one possible implementation, the sensors may be separate from each other, may be integrated, or may be part of the sensors separate from each other and part of the sensors integrated. The integration may be that a plurality of different sensing modules are respectively integrated on the same circuit board, or that a plurality of sensing functions are integrated into one circuit, etc., which is not limited in the present disclosure.

The memory 104 is used to store various data and executable programs generated during the monitoring of the target object by the relevant monitoring device, such as system programs for the monitoring device, various application programs, or algorithms for performing various specific functions. May include one or more computer program products that may include various forms of computer-readable storage media, such as volatile memory and/or non-volatile memory. Volatile memory can include, for example, random Access Memory (RAM) and/or cache memory (cache) and the like. The non-volatile memory may include, for example, read Only Memory (ROM), hard disk, flash memory, and the like. During the monitoring of the target object by the monitoring device, data stored locally may be stored in the memory 104, if needed.

The processor 101 may be a Central Processing Unit (CPU), an image processing unit (GPU), an Application Specific Integrated Circuit (ASIC), a Field Programmable Gate Array (FPGA), or other form of processing unit with data processing and/or instruction execution capabilities, and may control other components in the monitor to perform desired functions. For example, the processor 101 can include one or more embedded processors, processor cores, microprocessors, logic circuits, hardware Finite State Machines (FSMs), digital Signal Processors (DSPs), image processing units (GPUs), or combinations thereof.

The processor 101 of the monitoring device 100 of the present application is further configured to: and processing the data of the vital sign parameters to obtain the pulse pressure variation degree of the target object. The pulse pressure variability PPV may be generally a ratio of a difference between a maximum pulse pressure and a minimum pulse pressure in a respiratory cycle to a pulse pressure average, alternatively, the pulse pressure average may be a mean of the maximum pulse pressure and the minimum pulse pressure, and the pulse pressure may be a difference between a systolic pressure and a diastolic pressure of a single heart beat, and the processor 101 may calculate relevant data such as blood pressure (which may be an invasive arterial blood pressure or a non-invasive arterial blood pressure) in vital sign parameters, thereby obtaining pulse pressures in respective respiratory cycles, and calculate a ratio of the difference between the maximum pulse pressure and the minimum pulse pressure to the pulse pressure average in each respiratory cycle, thereby obtaining the pulse pressure variability. The processor 101 may also obtain the pulse pressure variability PPV based on other methods. It should be noted that, the PPV parameter is calculated according to the pulse pressure during one respiration period, and the PPV parameter is refreshed during a preset time period, so that the processor 101 can process the data of the vital sign parameter in real time to obtain the pulse pressure variation degree of the target object, and the display 103 displays the PPV parameter in real time, or includes a plurality of respiration periods during the preset time period, and can calculate a plurality of PPV parameters based on the vital sign parameters during the plurality of respiration periods, and then calculate an average value.

The processor 101 is also configured to: when a second user instruction input by a user through a first key is acquired, a menu window is displayed on the display 103 according to the second user instruction, the first key is arranged on a hot key area of the display 103, the first key can be, for example, a blood pressure measurement key (such as an NIBP measurement key or an IBP measurement key). Alternatively, in other examples, a switch key for turning on or off PPV detection and accuracy analysis functions is provided on the hotkey pad of the display 103.

In one example, the processor 101 is to: acquiring a first user instruction input by a user through a switch key; and processing the data of the vital sign parameters according to the first user instruction to obtain the pulse pressure variation degree of the target object, wherein the detection of the PPV parameters, the analysis of the correctness thereof and the like can be conveniently started according to the user requirement by setting the switch key. Optionally, the processor 101 may also process the data of vital sign parameters in response to detecting that the PPV parameter switch is turned on, so as to obtain the pulse pressure variation degree of the target object, and perform subsequent analysis on the pulse pressure variation degree accuracy, and so on.

The processor 101 of the monitoring device 100 of the present application is further configured to: the method comprises the steps of acquiring a plurality of associated parameters of a target object representing the accuracy of the pulse pressure variability, wherein the plurality of associated parameters can be any parameter capable of affecting the accuracy of the PPV, and optionally, the plurality of associated parameters comprise tidal volume when the target object is mechanically ventilated, heart rate of the target object, respiration rate of the target object and electrocardio parameter data of the target object, or can also comprise other associated parameters capable of affecting the accuracy of the pulse pressure variability. The heart rate and the electrocardio parameter data of the target object are obtained by real-time detection of the monitoring equipment in the monitoring process.

The monitoring device may obtain a plurality of associated parameters of the target subject that can affect the accuracy of the pulse pressure variability by any suitable method, for example, the monitoring device is communicatively coupled to a ventilator that mechanically ventilates the target subject via a communication interface, and the processor 101 is configured to: tidal volume and/or respiratory rate are obtained from the ventilator via the communication interface.

In another example, the monitoring device 100 may further comprise a respiratory mechanics module for measuring a tidal volume related parameter signal of the target subject when mechanically ventilated and outputting the parameter signal to the processor 101, the processor 101 may further be configured to process the tidal volume related parameter signal to obtain the tidal volume.

For another example, for respiratory rate (i.e., respiratory rate), the respiratory mechanics module of the monitoring device may be further configured to measure a respiratory rate related parameter signal of the subject when mechanically ventilated and output the parameter signal to the processor 101, and the processor 101 may be further configured to process the respiratory rate related parameter signal to obtain the respiratory rate. Alternatively, the processor 101 is further configured to: acquiring electrocardiographic parameter data (such as electrocardiogram) or blood oxygen saturation of a target object; and carrying out operation processing on the electrocardio parameter data or the blood oxygen saturation so as to obtain the respiration rate of the target object. Since there is a correlation between the amplitude variation of the electrocardiograph signal and the respiratory motion, the electrocardiograph signal generally includes respiratory information, and thus the electrocardiograph parameter data may be subjected to an arithmetic processing based on any suitable method known to those skilled in the art to obtain the respiratory rate of the target object, for example, respiratory information such as respiratory rate may be obtained by analyzing the amplitude variation of the electrocardiograph signal, or the processor 101 may also obtain respiratory information such as respiratory rate by a method for extracting respiratory information (ECG-Derived Respiratory Signal, abbreviated as EDR) from the electrocardiograph signal, a mixed signal dividing method, or the like. The processor 101 may also calculate the data of the blood oxygen saturation level based on any suitable method to obtain the respiratory rate, which is not particularly limited herein.

In order to ensure the credibility of the subsequent judgment result, the breathing machine can be further provided with a gas leakage compensation and pipeline compliance compensation mechanism; based on the electrocardio parameter data, various parameters are calculated or arrhythmia and the like are identified, a signal quality judgment and noise level evaluation mechanism can be added, so that the calculation accuracy of the various parameters is improved. Further, the processor 101 of the monitoring device 100 of the present application is also configured to: based on a plurality of associated parameters, the accuracy of the pulse pressure variation degree is determined, so that the result of the accuracy of the pulse pressure variation degree is fed back to a user, the user can find that the PPV value is wrong in time, the possibility that the user misjudges the physiological state of the patient due to the inaccurate PPV value is reduced, meanwhile, clinical staff can be helped to correct the reason causing the inaccurate PPV value in time, the accuracy of PPV parameter monitoring is guaranteed, and the liquid management of the doctor to the patient is better assisted. The processor 101 may compare the plurality of associated parameters with respective preset conditions to determine the accuracy of the PPV, e.g., the processor 101 determines the accuracy of the pulse pressure variation based on the plurality of associated parameters, including: judging whether the tidal volume is in a first preset range; judging whether the ratio of the heart rate to the respiration rate of the target object is in a second preset range or not; identifying whether the target object has an arrhythmia event based on the electrocardiographic parameter data; and determining that the result of the accuracy of the pulse pressure variability is accurate when the tidal volume is in the first preset range, the ratio of the heart rate to the respiration rate is in the second preset range, and the target object is not in the arrhythmia event, and determining that the result of the accuracy of the pulse pressure variability is doubtful when the tidal volume is not in the first preset range, and/or the ratio of the heart rate value to the respiration rate is not in the second preset range, and/or the target object is in the arrhythmia event, wherein the accuracy doubtful reflects that the result of the PPV may be inaccurate.

The first preset range may be any suitable range capable of ensuring that the PPV is accurate, for example, the first preset range is greater than or equal to 8ml/kg, i.e., when PPV is measured, the tidal volume needs to be greater than or equal to 8ml/kg in order to ensure that the result is accurate.

The second preset range may be any suitable range capable of ensuring that PPV is accurate, for example, the second preset range is greater than or equal to 4, that is, when PPV is measured, the ratio of heart rate to respiration rate should be greater than or equal to 4 in order to ensure that the result is accurate.

In one example, the processor 101 identifies whether an arrhythmia event is present in the target subject based on the electrocardiographic parameter data, including but not limited to ventricular fibrillation, ventricular tachycardia, or asystole, etc., the processor may identify the electrocardiographic parameter data using any suitable method known to those skilled in the art to determine whether an arrhythmia event is present, e.g., the processor may identify and classify electrocardiographic signals using machine learning or deep learning methods (e.g., may be based on neural network models) to identify arrhythmia events. Optionally, the processor 101 may analyze and identify the electrocardiographic parameter data for a predetermined period of time (e.g., the predetermined period of time may be 1s, 2s, 3s, or other suitable period of time) to determine an arrhythmia event.

The combined system of the monitoring device and the breathing machine can analyze the above 3 indexes of tidal volume, the ratio of heart rate to breathing rate and whether arrhythmia event exists in real time through the processor of the monitoring device, so that the PPV error parameter value is prevented from misleading clinical judgment.

The monitoring device 100 of the present application further comprises a display 103 for displaying at least the data of vital sign parameters on a display interface. To facilitate the user in obtaining various key information, various information may be displayed in different areas, for example, as shown in fig. 2, a first parameter area for displaying data of vital sign parameters and a prompt information area 302 (also referred to as an alarm display area) for displaying alarm information or prompt information may be included on the display interface 300. The first parameter region may include, among other things, a waveform region 303 (e.g., for displaying waveforms of one or more types of vital sign parameters, including but not limited to, electrocardiography (ECG), blood oxygen saturation, respiration (Resp), mean arterial blood pressure (arterial pressure, ART), etc.), a waveform parameter region 304 (for displaying data of vital sign parameters corresponding to the waveforms), an amorphous parameter region 305 (e.g., for displaying data of physiological parameters of a subject such as: body temperature, noninvasive blood pressure NIBP, pulse rate PR, vital sign parameters at one or more moments (e.g. heart rate HR, blood oxygen saturation, respiration rate, blood pressure BP)), etc., other display areas may also be included on the display interface, such as a patient information area 301 for displaying patient information (e.g. displaying a type of patient, e.g. adult, child, neonate, etc.), a device prompt information area 306 (e.g. prompt information area for displaying one or more of function attributes, function settings and function keys, e.g. for displaying wireless information, volume information, power information, etc.), a hotkey area 307 (i.e. a navigation area in which one or more hotkeys are displayed, e.g. review, standby, alarm settings, main menu, alarm reset, alarm pause, NIBB start/stop, NIBP measurement, NIBP stop all, IBO calibration zero, etc.), various function keys may be icons and/or text function keys, the user may implement the corresponding functions by clicking the hotkey of the hotkey area, e.g. clicking the alarm settings hotkey may pop up the relevant settings window about the relevant settings. The layout of each display area can be reasonably set according to actual needs. For example, the waveform parameter area is located at one side of the waveform area, the hot key area is arranged at the bottom end of the display interface, and the amorphous parameter area is arranged between the intelligent hot key area and the waveform area. The prompt section 302 may be disposed at any suitable location on the display interface of the display 103, for example, the prompt section 302 is located above or to one side of the waveform parameter area, and for example, the prompt section 302 is located above, below, or to one side of the waveform area. The second parameter area 308 is used to display the value of PPV, where the second parameter area 308 may be located outside the waveform parameter area 304, or the second parameter area 308 may also be a sub-area of the waveform parameter area 304, where PPV may be obtained according to the mean arterial pressure calculation, and thus may be correspondingly displayed outside the ART waveform, and in one example, parameters such as pulse rate, pulse intensity, etc. may also be displayed in the second parameter area 308.

In one example, the processor 101 is further configured to output corresponding prompt information according to the accuracy control, where the prompt information is used to characterize whether the pulse pressure variation degree is accurate. For example, as shown in fig. 2, the processor is further configured to: the display form of the pulse pressure variation degree displayed on the display 103 is adjusted according to the accuracy result so as to prompt a user, for example, when the accuracy result is accurate, the display form is a first display form, and when the accuracy result is suspicious, the display form is a second display form, wherein the first display form and the second display form are different; the display 103 is used for displaying the data of vital sign parameters and the data of pulse pressure variation in a display form, and the data are displayed through the monitor, so that the inaccuracy of the PPV parameters of the user is timely prompted when necessary, the user is helped to correct, the accuracy of monitoring the PPV parameters is ensured, and the normal display of the PPV parameter values is restored until the processor 101 monitors and analyzes to confirm that the PPV accuracy conditions are all met.

The monitor and ventilator combined system performs background real-time analysis, and if an analysis result that the PPV accuracy condition is not met (that is, when the processor 101 analyzes and judges that the PPV accuracy is in doubt) is returned, one of the following modes is used to prompt on the display 103 of the monitor: the first display form and the second display form may be any suitable differentiated display form for displaying PPV values, for example, the first display form and the second display form have different fonts, and for example, the first display form and the second display form have different font colors, one of the first display form and the second display form is a flashing display, and the other is a non-flashing display; for example, one of the first display form and the second display form is a hollow display pulse pressure variation value, the other is a solid display pulse pressure variation value, and for example, the first display form and the second display form have different ground patterns; for another example, one of the first display form and the second display form is highlighted, and the other is normally displayed. For example, the second display form includes displaying the value of the pulse pressure variation instead of the preset pattern, for example, the value of PPV may be displayed by an asterisk, a horizontal line (for example, a double horizontal line or a single horizontal line), etc., and when the value of PPV is accurate, the value of PPV may be directly displayed, so as to realize differentiated display.

In other examples, the first display form includes displaying the first mark while displaying the value of the pulse pressure variability adjacent to the value of the pulse pressure variability, the second display form includes displaying the value of the pulse pressure variability but not displaying the first mark or displaying the second mark adjacent to the pulse pressure variability different from the first mark, for example, when the accuracy of the value of the pulse pressure variability is suspected, the mark may be made outside the displayed value of the PPV by the first mark such as an asterisk or any other suitable mark, and when the value of the PPV is accurate, only the value of the PPV may be displayed without displaying the first mark, or alternatively, the value adjacent to the PPV may display the second mark different from the first mark such as the first mark and the second mark in different patterns, or the first mark and the second mark may be marks made in different numbers of the same patterns, or the like.

In one example, the monitor may be further provided with an alarm device, for example, the alarm device may alarm for abnormal vital sign parameters, or alarm for a condition of the patient, or the processor 101 may generate alarm information (for example, an alarm signal) when a connection abnormality, an operation state abnormality, or the like occurs in each device of the monitor. The alarm device is configured to alarm when the accuracy of the value of the PPV is suspected, including but not limited to alarm modes such as light, sound and the like, and the specific forms can be a flashing LED lamp, a buzzer, a loudspeaker and the like, for example, when the alarm device is a loudspeaker, a prompt tone of a result of the accuracy of the value of the PPV, such as voice broadcast and the like, can also be output, so that the requirement on the strength of an alarm signal and the like is satisfied, and the requirement on the strength and the like of an observer can be sufficiently brought into charge and vigilance. In this way, real-time alerting may be implemented to prompt the user.

The processor 101 is further configured to output corresponding prompt information according to the accuracy control, where the prompt information is used to characterize whether the pulse pressure variation is accurate. In one example, continuing to refer to fig. 2, the processor 101 is further configured to output a corresponding prompt according to the accuracy result, where the display 103 may display the prompt in a vicinity of the PPV displayed, for example, the display 103 may display the prompt in a prompt area, or may also display the prompt in a second parameter area. Optionally, the prompt information includes an accurate result, and the accurate result may be accurate or suspicious, where when the result is accurate, the corresponding prompt information may not be displayed, and only when the PPV accurate result is suspicious, the prompt information is displayed, optionally, the prompt information may further include a reason for judging that the PPV accurate result is suspicious, and by outputting the PPV accurate result as the reason for suspicious, the clinical staff can be helped to correct the reason for inaccurate PPV value in time, so as to ensure the accuracy of PPV parameter monitoring, and facilitate better assisting the doctor in managing the liquid of the patient.

In one example, the plurality of associated parameters includes tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and electrocardiographic parameter data of the target subject, and the reason when the PPV accuracy is determined to be suspected includes one or more of the following reasons: the tidal volume is not in the first preset range, the ratio of heart rate value to respiration rate is not in the second preset range, and the target subject has an arrhythmia event, wherein the target subject has an arrhythmia event determined based on the electrocardiographic parameter data of the target subject. For example, as shown in fig. 2, in the prompt message area 302, prompt messages indicating that the PPV value is in doubt are directly output, and further, the reason why the inaccuracy is caused is that the ratio of the heart rate to the respiration rate is less than 4, and is lower than the first preset range, that is, lower than the normal range, so that the PPV value may be inaccurate. For another example, the unqualified determination results of the tidal volume, the ratio of the heart rate to the respiratory rate, the abnormal heart rate event, etc. may be directly displayed on the display interface of the display 103, or the first preset range corresponding to the tidal volume, the second preset range corresponding to the ratio of the heart rate to the respiratory rate, the current tidal volume, the current ratio of the heart rate to the respiratory rate, etc. may be displayed, and the user may determine the accuracy according to these conditions.

In one example, display 103 may also display prompts, such as highlighting, blinking, etc., via a differentiated display. Optionally, when the reasons include multiple reasons, the display 103 is configured to alternately display the multiple reasons, so that a user can timely learn that the value of PPV is inaccurate, and/or the display 103 may be further configured to display the multiple reasons differently in a preset display form, for example, the multiple reasons may be displayed simultaneously, and the multiple reasons are respectively displayed in different fonts and/or different colors and/or different shading, etc.

Further, in the embodiment of the present invention, the validity (also called accuracy) of the PPV parameter is determined in real time according to the foregoing parameters such as the tidal volume, the ratio of the heart rate to the respiratory rate, and the electrocardiograph parameter data, and in the real-time monitoring process, the processor 101 determines whether the PPV parameter switch is turned on or whether the PPV parameter needs to be displayed, if the switch is turned on or the PPV parameter needs to be displayed, the processor 101 determines the validity of the PPV parameter from the tidal volume, the ratio of the heart rate to the respiratory rate, and the arrhythmia, and finally prompts the determination result to the user. In some embodiments, the processor 101 may further determine whether the PPV parameter accuracy determination function is activated, that is, the monitoring device may provide a PPV parameter switch and a PPV accuracy determination switch, and when the PPV parameter switch is turned on and the PPV accuracy determination switch is turned on, the processor 101 determines the validity of the PPV parameter, and prompts the user with the result of the validity determination.

In one example, a review key is provided within the hotkey of the display 103, and the processor 101 is further configured to: a review instruction input by a user through a review button is acquired, and based on the review instruction, history data of the pulse pressure variability is displayed on a review display interface of the display 103, wherein the history data of the accurate pulse pressure variability is displayed in different manners (for example, different color displays, different font displays, different shading displays, etc.) from the history data of the suspected pulse pressure variability, optionally, the history data of the suspected pulse pressure variability may also display a cause that the accuracy of the history data of the pulse pressure variability is suspected, etc. The user can trace back the data of the PPV accuracy by calling the historical data of the pulse pressure variation degree.

In summary, the monitoring device according to the application can determine the accuracy of the pulse pressure variation based on a plurality of associated parameters, so as to feed back the result of the accuracy of the pulse pressure variation to the user, thereby facilitating the user to find that the PPV value is wrong in time, reducing the possibility of misjudging the physiological state of the patient by the user due to inaccurate PPV value, and simultaneously helping clinical staff to correct the cause of inaccurate PPV value in time, thereby ensuring the accuracy of PPV parameter monitoring, and facilitating better assisting doctors in managing the liquid of the patient.

In another embodiment of the present application, a monitoring device is provided for monitoring vital sign parameters of a target subject, as further shown in fig. 1, comprising: a signal acquisition circuit 102 for acquiring vital sign signals of a target object; a processor 101 for processing the vital sign signals to obtain vital sign parameters of the target object; the processor 101 is also configured to: processing the data of vital sign parameters to obtain monitoring parameters for characterizing the capacity reactivity of the target object; acquiring a plurality of associated parameters of a target object which characterizes the accuracy of the monitoring parameters; based on a plurality of associated parameters, the accuracy of the monitoring parameters is determined, so that the accuracy result of the monitoring parameters is fed back to the user, the user can find out that the value of the monitoring parameters is wrong in time, the possibility that the user misjudges the physiological state of the patient due to inaccurate monitoring parameters is reduced, meanwhile, the method can help clinical staff correct the reasons causing the inaccuracy of the monitoring parameters in time, the accuracy of capacity reactivity monitoring is guaranteed, and the doctor can be assisted to manage the liquid of the patient better.

Optionally, the monitoring parameters include stroke volume variability and/or pulse pressure variability, or any other suitable monitoring parameter for characterizing the volume responsiveness of the target subject.

It should be noted that, the foregoing explanation and explanation are made for the case that the monitored parameter is the pulse pressure variation, and specific details of each pulse volume variation may refer to the foregoing description of the pulse pressure variation, which is not described herein.

Further, in still another embodiment of the present application, there is provided a monitoring device for monitoring vital sign parameters of a target subject, as further shown in fig. 1, including: a signal acquisition circuit 102 for acquiring vital sign signals of a target object; a processor 101 for processing the vital sign signals to obtain vital sign parameters of the target object; the processor 101 is also configured to: processing the data of vital sign parameters to obtain monitoring parameters for characterizing the capacity reactivity of the target object; acquiring the associated characteristics of a target object representing the accuracy of the monitoring parameters; based on the correlation characteristics, the accuracy of the monitored parameters is determined. Optionally, the associated feature of the target object includes a disease condition of the target object, for example, the disease condition of the target object may be obtained through input of a user or the disease condition of the target object may be obtained through an electronic medical record of the target object.

The disease condition of the target subject refers to a condition that can affect the accuracy of monitoring parameters such as the stroke volume variability and/or the pulse pressure variability, for example, when the target subject suffers from a pulmonary disease such as a pulmonary disorder, the accuracy of the values of the stroke volume variability and/or the pulse pressure variability cannot be guaranteed.

It should be noted that, for some detailed descriptions of the monitoring device according to the embodiment of the present application, reference may be made to the foregoing, and a description will not be given here.

The monitoring device of the embodiment of the application can also judge the accuracy of the monitoring parameters such as the variability of each pulse volume and/or the variability of the pulse pressure by acquiring the associated characteristics of the target object so as to feed back the accuracy result of the variability of the pulse pressure to the user, thereby being convenient for the user to find that the numerical value of the monitoring parameters is wrong in time and further reducing the possibility of misjudging the physiological state of the patient due to inaccurate monitoring parameters.

The method for determining accuracy of pulse pressure variability according to the present application will be described with reference to fig. 3, and the method may be based on the foregoing monitoring device as an execution subject, where the various technical features may be combined without conflict.

As an example, as shown in fig. 3, the method for determining the accuracy of the pulse pressure variation degree of the present application includes the following steps S310 to S350:

first, in step S310, a vital sign signal of a target object is acquired.

The monitoring device has one or more sensors by which signals of vital sign parameters of a subject (i.e. a target subject) monitored by the monitoring device are detected, e.g. the vital sign parameters comprise at least one of the following parameters: blood pressure, respiration rate, heart rate, body temperature, pulse rate, blood oxygen saturation, cardiac output, end-tidal carbon dioxide, electroencephalogram, and electrocardiographic parameter data such as electrocardiogram, etc. The monitoring device may also be communicatively coupled to the ventilator to obtain various data detected by the ventilator, such as tidal volume, respiratory rate, and the like.

Next, in step S320, the vital sign signal is processed to obtain vital sign parameters of the target subject. Various processes may be performed via the processor of the monitoring device to obtain vital sign parameters. Reference is made in particular to the preceding description.

Next, in step S330, the data of vital sign parameters are processed to obtain the pulse pressure variability of the target subject. The method for obtaining the variation of pulse pressure can be referred to as the foregoing.

In step S340, a plurality of associated parameters of the target object characterizing the accuracy of the pulse pressure variation degree are acquired; optionally, the plurality of associated parameters include tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and electrocardiographic parameter data of the target subject, or other parameters that can affect accuracy of pulse pressure variability.

The plurality of associated parameters of the target subject may be obtained by one or more of, for example, obtaining tidal volume and/or respiratory rate from a ventilator that mechanically ventilates the target subject; and/or acquiring electrocardiographic parameter data or blood oxygen saturation of the target object; and carrying out operation processing on the electrocardio parameter data or the blood oxygen saturation so as to obtain the respiration rate of the target object. Or may be in other suitable ways.

In step S350, the accuracy of the pulse pressure variation is determined based on the plurality of correlation parameters.

In one example, determining the accuracy of the pulse pressure variability based on the plurality of correlation parameters includes: judging whether the tidal volume is in a first preset range, optionally, the first preset range is greater than or equal to 8ml/kg; judging whether the ratio of the heart rate to the respiration rate of the target object is in a second preset range or not; optionally, the second preset range is greater than or equal to 4; identifying whether the target object has an arrhythmia event based on the electrocardiographic parameter data; and when the tidal volume is in the first preset range, the ratio of the heart rate to the respiratory rate is in the second preset range, and the target object is not in arrhythmia event, determining that the result of the accuracy of the pulse pressure variation is accurate. When the tidal volume is not within the first preset range and/or the ratio of the heart rate value to the respiration rate is not within the second preset range and/or the target subject has an arrhythmia event, the result of determining the accuracy of the pulse pressure variability is doubtful.

When the accuracy of the pulse pressure variation degree is determined to be doubtful, a prompt message can be output, for example, a display form of the pulse pressure variation degree displayed on a display is adjusted according to the accuracy result, wherein the display is used for displaying data of vital sign parameters and displaying the data of the pulse pressure variation degree in a display form. In one example, when the result of the accuracy is accurate, the display form is a first display form, and when the result of the accuracy is suspicious, the display is displayed as a second display form, wherein the first display form and the second display form have different fonts; and/or the first display form and the second display form have different font colors; and/or one of the first display form and the second display form is a blinking display, and the other is a non-blinking display; and/or one of the first display form and the second display form is hollow for displaying the pulse pressure variation degree value, and the other is solid for displaying the pulse pressure variation degree value; and/or the first display form and the second display form have different shading; and/or one of the first display form and the second display form is highlighted; and/or the first display form comprises displaying the pulse pressure variability value in a specific pattern instead; and/or the first display form comprises displaying the first mark adjacent to the pulse pressure variation value when the pulse pressure variation value is displayed, and the second display form comprises displaying the pulse pressure variation value but not displaying the first mark or displaying the second mark which is different from the first mark adjacent to the pulse pressure variation value.

In another example, in addition to the above-mentioned change in the PPV display form as the prompt information, an additional prompt information may be output, or only the prompt information may be output, for example, the corresponding prompt information may be output according to the result of accuracy; displaying the data of vital sign parameters, the data of pulse pressure variation degree and prompt information. Optionally, the prompt information includes an accuracy result, and the reason when the accuracy result is determined to be in doubt, where the prompt information may be displayed in a text description manner, or may also be displayed in a manner such as a prompt tone, so as to prompt the user.

In one example, the reasons why PPV accuracy is in doubt may include one or more of the following reasons: the tidal volume is not in the first preset range, the ratio of heart rate value to respiration rate is not in the second preset range, and the target subject has an arrhythmia event, wherein the target subject has an arrhythmia event determined based on the electrocardiographic parameter data of the target subject.

The method of the embodiment of the application can also judge the accuracy of the monitoring parameters such as the pulse volume variation and/or the pulse pressure variation by acquiring the associated characteristics of the target object so as to feed back the result of the accuracy of the pulse pressure variation to the user, thereby being convenient for the user to find that the numerical value of the monitoring parameters is wrong in time and further reducing the possibility of misjudging the physiological state of the patient due to inaccurate monitoring parameters.

In addition, the embodiment of the invention also provides a computer storage medium, on which the computer program is stored. One or more computer program instructions may be stored on a computer readable storage medium, in which a processor may execute the program instructions stored by the storage device to perform the functions of the embodiments of the present invention herein (as implemented by the processor) and/or other desired functions, for example, to perform the corresponding steps of a method of determining the accuracy of pulse pressure variability according to embodiments of the present invention, various applications and various data, such as various data used and/or generated by the applications, etc., may also be stored.

For example, the computer storage medium may include, for example, a memory card of a smart phone, a memory component of a tablet computer, a hard disk of a personal computer, read-only memory (ROM), erasable programmable read-only memory (EPROM), portable compact disc read-only memory (CD-ROM), USB memory, or any combination of the foregoing storage media.

Although the illustrative embodiments have been described herein with reference to the accompanying drawings, it is to be understood that the above illustrative embodiments are merely illustrative and are not intended to limit the scope of the present invention thereto. Various changes and modifications may be made therein by one of ordinary skill in the art without departing from the scope and spirit of the invention. All such changes and modifications are intended to be included within the scope of the present invention as set forth in the appended claims.

Those of ordinary skill in the art will appreciate that the various illustrative elements and algorithm steps described in connection with the embodiments disclosed herein may be implemented as electronic hardware, or combinations of computer software and electronic hardware. Whether such functionality is implemented as hardware or software depends upon the particular application and design constraints imposed on the solution. Skilled artisans may implement the described functionality in varying ways for each particular application, but such implementation decisions should not be interpreted as causing a departure from the scope of the present application.

In the several embodiments provided by the present application, it should be understood that the disclosed apparatus and method may be implemented in other ways. For example, the above-described device embodiments are merely illustrative, e.g., the division of the elements is merely a logical functional division, and there may be additional divisions when actually implemented, e.g., multiple elements or components may be combined or integrated into another device, or some features may be omitted or not performed.

In the description provided herein, numerous specific details are set forth. However, it is understood that embodiments of the application may be practiced without these specific details. In some instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure an understanding of this description.

Similarly, it should be appreciated that in order to streamline the invention and aid in understanding one or more of the various inventive aspects, various features of the invention are sometimes grouped together in a single embodiment, figure, or description thereof in the description of exemplary embodiments of the invention. However, the method of the present invention should not be construed as reflecting the following intent: i.e., the claimed invention requires more features than are expressly recited in each claim. Rather, as the following claims reflect, inventive aspects lie in less than all features of a single disclosed embodiment. Thus, the claims following the detailed description are hereby expressly incorporated into this detailed description, with each claim standing on its own as a separate embodiment of this invention.

It will be understood by those skilled in the art that all of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and all of the processes or units of any method or apparatus so disclosed, may be combined in any combination, except combinations where the features are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings), may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise.

Furthermore, those skilled in the art will appreciate that while some embodiments described herein include some features but not others included in other embodiments, combinations of features of different embodiments are meant to be within the scope of the invention and form different embodiments. For example, in the claims, any of the claimed embodiments may be used in any combination.

Various component embodiments of the invention may be implemented in hardware, or in software modules running on one or more processors, or in a combination thereof. Those skilled in the art will appreciate that some or all of the functions of some of the modules according to embodiments of the present invention may be implemented in practice using a microprocessor or Digital Signal Processor (DSP). The present invention can also be implemented as an apparatus program (e.g., a computer program and a computer program product) for performing a portion or all of the methods described herein. Such a program embodying the present invention may be stored on a computer readable medium, or may have the form of one or more signals. Such signals may be downloaded from an internet website, provided on a carrier signal, or provided in any other form.

It should be noted that the above-mentioned embodiments illustrate rather than limit the invention, and that those skilled in the art will be able to design alternative embodiments without departing from the scope of the appended claims. In the claims, any reference signs placed between parentheses shall not be construed as limiting the claim. The invention may be implemented by means of hardware comprising several distinct elements, and by means of a suitably programmed computer. In the unit claims enumerating several means, several of these means may be embodied by one and the same item of hardware. The use of the words first, second, third, etc. do not denote any order. These words may be interpreted as names.

Claims

A monitoring device for monitoring vital sign parameters of a target subject, comprising:

the signal acquisition circuit is used for acquiring vital sign signals of the target object;

a processor for processing the vital sign signals to obtain vital sign parameters of the target subject; the processor is further configured to:

processing the data of the vital sign parameters to obtain the pulse pressure variation degree of the target object;

Acquiring a plurality of associated parameters of the target object, which characterize the accuracy of the pulse pressure variation;

and determining the accuracy of the pulse pressure variation degree based on the plurality of associated parameters.
The monitoring device of claim 1, wherein the plurality of associated parameters includes tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and cardiac parameter data of the target subject.
The monitoring device of claim 2, further comprising a communication interface through which the monitoring device is communicatively coupled to a ventilator that mechanically ventilates the target subject, the processor being configured to: the tidal volume and/or the respiratory rate are obtained from the ventilator through the communication interface.
The monitoring device of claim 2, further comprising a respiratory mechanics module,

the respiratory mechanics module is used for measuring a parameter signal related to tidal volume of the target object when mechanical ventilation is carried out, and the processor is used for processing the parameter signal related to tidal volume so as to obtain tidal volume; and/or the number of the groups of groups,

The respiratory mechanics module is used for measuring a parameter signal related to the respiratory rate of the target object when mechanical ventilation is carried out, and the processor is used for processing the parameter signal related to the respiratory rate so as to obtain the respiratory rate.
The monitoring device of claim 2, wherein the processor is further configured to:

acquiring electrocardio parameter data or blood oxygen saturation of the target object;

and carrying out operation processing on the electrocardio parameter data or the blood oxygen saturation so as to obtain the respiration rate of the target object.
The monitoring device of claim 2, wherein the processor determines an accuracy of the pulse pressure variability based on the plurality of correlation parameters, comprising:

judging whether the tidal volume is in a first preset range or not;

judging whether the ratio of the heart rate to the respiratory rate of the target object is in a second preset range or not;

identifying whether an arrhythmia event exists in the target object based on the electrocardiographic parameter data; and

and when the tidal volume is in a first preset range, the ratio of the heart rate to the respiratory rate is in a second preset range, and the target object is not provided with arrhythmia events, determining that the result of the accuracy of the pulse pressure variation is accurate.
The monitoring device of claim 2, wherein the processor determines an accuracy of the pulse pressure variability based on the plurality of correlation parameters, comprising:

judging whether the tidal volume is in a first preset range or not;

judging whether the ratio of the heart rate to the respiratory rate of the target object is in a second preset range or not;

identifying whether an arrhythmia event exists in the target object based on the electrocardiographic parameter data; and

and when the tidal volume is not in a first preset range, and/or the ratio of the heart rate value to the respiratory rate is not in a second preset range, and/or the target object has an arrhythmia event, determining that the accuracy of the pulse pressure variability is doubtful.
The monitoring device of claim 6 or 7, wherein the first preset range is greater than or equal to 8ml/kg;

the second preset range is greater than or equal to 4.
The monitoring device of claim 1, wherein the monitoring device further comprises a display, the processor further configured to: adjusting the display form of the pulse pressure variation displayed on a display according to the accuracy result;

the display is used for displaying the data of the vital sign parameters and the data of the pulse pressure variation degree in the display form.
The monitoring device of claim 9, wherein the display form is a first display form when the accuracy result is accurate and a second display form when the accuracy result is suspect, wherein the first display form and the second display form are different.
The monitoring device of claim 10, wherein the first display form and the second display form have different fonts; and/or

The first display form and the second display form have different font colors; and/or

One of the first display form and the second display form is a flicker display, and the other is a non-flicker display; and/or

One of the first display form and the second display form is hollow to display the pulse pressure variation degree value, and the other is solid to display the pulse pressure variation degree value; and/or

The first display form and the second display form have different shading; and/or

One of the first display form and the second display form is highlighted; and/or

The second display form comprises a preset pattern for replacing and displaying the numerical value of the pulse pressure variation degree; and/or

The first display form includes displaying a first mark adjacent to the value of the pulse pressure variation while displaying the value of the pulse pressure variation, and the second display form includes displaying the value of the pulse pressure variation but not displaying the first mark or displaying a second mark different from the first mark adjacent to the value of the pulse pressure variation.
The monitoring device of claim 1, wherein the monitoring device further comprises a display, the processor is further configured to output corresponding prompt information according to the accuracy result, and a display interface of the display includes a first parameter area for displaying data of the vital sign parameter, a second parameter area, a prompt information area, and a hotkey area, wherein the first parameter area includes a waveform area for displaying a waveform of the vital sign parameter and a waveform parameter area, the second parameter area is used for displaying the pulse pressure variability value, and the prompt information area is used for displaying the prompt information, or the second parameter area is further used for displaying the prompt information.
The monitoring device of claim 12, wherein the prompt includes a result of the accuracy and a determination that the result of the accuracy is a cause of the doubt.
The monitoring device of claim 13, wherein the plurality of associated parameters include tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and cardiac parameter data of the target subject, the reasons including one or more of: the tidal volume is not in a first preset range, the ratio of heart rate value to respiration rate is not in a second preset range, and the target subject has an arrhythmia event, wherein the target subject has an arrhythmia event determined based on the electrocardiographic parameter data of the target subject.
The monitoring device of claim 13, wherein when the cause comprises a plurality of causes, the display is configured to alternately display the plurality of causes and/or the display is configured to differentially display the plurality of causes in a preset display format.
The monitoring device of claim 1, wherein the monitoring device comprises a display, a hotkey pad is included on a display interface of the display, a review key is disposed within the hotkey pad, and the processor is further configured to: and acquiring a review instruction input by a user through the review button, and displaying historical data of the pulse pressure variation degree on a review display interface of the display based on the review instruction, wherein the accurate historical data of the pulse pressure variation degree and the historical data of the suspected pulse pressure variation degree are displayed in different modes.
A monitoring device for monitoring vital sign parameters of a target subject, comprising:

the signal acquisition circuit is used for acquiring vital sign signals of the target object;

a processor for processing the vital sign signals to obtain vital sign parameters of the target subject; the processor is further configured to:

processing the data of the vital sign parameters to obtain monitoring parameters for characterizing the volume responsiveness of the target object;

acquiring a plurality of associated parameters of the target object, which characterize the accuracy of the monitoring parameters;

based on the plurality of associated parameters, an accuracy of the monitored parameters is determined.
The monitoring device of claim 17, wherein the monitored parameters include a variability of stroke volume and/or a variability of pulse pressure.
A monitoring device for monitoring vital sign parameters of a target subject, comprising:

the signal acquisition circuit is used for acquiring vital sign signals of the target object;

a processor for processing the vital sign signals to obtain vital sign parameters of the target subject; the processor is further configured to:

Processing the data of the vital sign parameters to obtain monitoring parameters for characterizing the volume responsiveness of the target object;

acquiring associated features of the target object, which characterize the accuracy of the monitoring parameters;

and determining the accuracy of the monitoring parameters based on the correlation characteristics.
The monitoring device of claim 19, wherein the associated characteristic comprises a diseased condition of the target subject.
The monitoring device of claim 20, wherein the condition of the subject is that the subject has a pulmonary disorder.
A method of determining accuracy of pulse pressure variability, the method comprising:

acquiring vital sign parameters of a target object;

processing the data of the vital sign parameters to obtain the pulse pressure variation degree of the target object;

acquiring a plurality of associated parameters of the target object, which characterize the accuracy of the pulse pressure variation;

and determining the accuracy of the pulse pressure variation degree based on the plurality of associated parameters.
The method of claim 22, wherein the plurality of associated parameters includes tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and electrocardiographic parameter data of the target subject;

The obtaining a plurality of associated parameters of the target object characterizing accuracy of the pulse pressure variability includes:

obtaining the tidal volume and/or the respiratory rate from a ventilator that mechanically ventilates the target subject;

and/or acquiring electrocardiographic parameter data or blood oxygen saturation of the target object; and carrying out operation processing on the electrocardio parameter data or the blood oxygen saturation so as to obtain the respiration rate of the target object.
The method of claim 23, wherein the plurality of associated parameters includes tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and cardiac parameter data of the target subject, the determining accuracy of the pulse pressure variability based on the plurality of associated parameters comprising:

judging whether the tidal volume is in a first preset range or not;

judging whether the ratio of the heart rate to the respiratory rate of the target object is in a second preset range or not;

identifying whether an arrhythmia event exists in the target object based on the electrocardiographic parameter data; and

and when the tidal volume is in a first preset range, the ratio of the heart rate to the respiratory rate is in a second preset range, and the target object is not provided with arrhythmia events, determining that the result of the accuracy of the pulse pressure variation is accurate.
The method of claim 22, wherein the plurality of associated parameters includes tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and cardiac parameter data of the target subject, the determining accuracy of the pulse pressure variability based on the plurality of associated parameters comprising:

judging whether the tidal volume is in a first preset range or not;

judging whether the ratio of the heart rate to the respiratory rate of the target object is in a second preset range or not;

identifying whether an arrhythmia event exists in the target object based on the electrocardiographic parameter data; and

and when the tidal volume is not in a first preset range, and/or the ratio of the heart rate value to the respiratory rate is not in a second preset range, and/or the target object has an arrhythmia event, determining that the accuracy of the pulse pressure variability is doubtful.
The method of claim 24 or 25, wherein the first preset range is greater than or equal to 8ml/kg;

the second preset range is greater than or equal to 4.
The method of claim 32, wherein the method further comprises: and adjusting a display form of the pulse pressure variation displayed on a display according to the accuracy result, wherein the display is used for displaying the data of the vital sign parameters and the data of the pulse pressure variation in the display form.
The method of claim 27, wherein the display form is a first display form when the result of the accuracy is accurate and a second display form when the result of the accuracy is suspect, wherein the first display form and the second display form have different fonts; and/or

The first display form and the second display form have different font colors; and/or

One of the first display form and the second display form is a flicker display, and the other is a non-flicker display; and/or

One of the first display form and the second display form is hollow to display the pulse pressure variation degree value, and the other is solid to display the pulse pressure variation degree value; and/or

The first display form and the second display form have different shading; and/or

One of the first display form and the second display form is highlighted; and/or

The first display form comprises replacing and displaying the pulse pressure variability value with a specific pattern; and/or

The first display form includes displaying a first mark adjacent to the pulse pressure variability value while displaying the pulse pressure variability value, and the second display form includes displaying the pulse pressure variability value but not displaying a first mark or displaying a second mark different from the first mark adjacent to the pulse pressure variability value.
The method of any one of claims 22 to 28, further comprising:

outputting corresponding prompt information according to the accuracy result;

displaying the data of the vital sign parameters, the data of the pulse pressure variation degree and the prompt information.
The method of claim 29, wherein the hint information includes a result of the accuracy and determining that the result of the accuracy is a cause of a doubt.
The method of claim 30, wherein the plurality of associated parameters includes tidal volume when mechanically ventilating the target subject, heart rate of the target subject, respiration rate of the target subject, and cardiac parameter data of the target subject, the reasons including one or more of: the tidal volume is not in a first preset range, the ratio of heart rate value to respiration rate is not in a second preset range, and the target subject has an arrhythmia event, wherein the target subject has an arrhythmia event determined based on the electrocardiographic parameter data of the target subject.