CN116813620A - Chimeric body for degrading GPX4 based on HSP90 protein targeting, preparation method and application - Google Patents
Chimeric body for degrading GPX4 based on HSP90 protein targeting, preparation method and application Download PDFInfo
- Publication number
- CN116813620A CN116813620A CN202310579083.3A CN202310579083A CN116813620A CN 116813620 A CN116813620 A CN 116813620A CN 202310579083 A CN202310579083 A CN 202310579083A CN 116813620 A CN116813620 A CN 116813620A
- Authority
- CN
- China
- Prior art keywords
- gpx4
- hsp90 protein
- degradation
- gpx
- chimeric body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Abstract
Description
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202310579083.3A CN116813620A (en) | 2023-05-19 | 2023-05-19 | Chimeric body for degrading GPX4 based on HSP90 protein targeting, preparation method and application |
Applications Claiming Priority (1)
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CN202310579083.3A CN116813620A (en) | 2023-05-19 | 2023-05-19 | Chimeric body for degrading GPX4 based on HSP90 protein targeting, preparation method and application |
Publications (1)
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CN116813620A true CN116813620A (en) | 2023-09-29 |
Family
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Family Applications (1)
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CN202310579083.3A Pending CN116813620A (en) | 2023-05-19 | 2023-05-19 | Chimeric body for degrading GPX4 based on HSP90 protein targeting, preparation method and application |
Country Status (1)
Country | Link |
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CN (1) | CN116813620A (en) |
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2023
- 2023-05-19 CN CN202310579083.3A patent/CN116813620A/en active Pending
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