CN116807667A - Automatic broken end equipment for experimental animals in hyperbaric chamber - Google Patents
Automatic broken end equipment for experimental animals in hyperbaric chamber Download PDFInfo
- Publication number
- CN116807667A CN116807667A CN202310929152.9A CN202310929152A CN116807667A CN 116807667 A CN116807667 A CN 116807667A CN 202310929152 A CN202310929152 A CN 202310929152A CN 116807667 A CN116807667 A CN 116807667A
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- Prior art keywords
- pressure
- fixed
- plate
- sliding
- inverted
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- 238000010171 animal model Methods 0.000 title claims abstract description 67
- 241001669679 Eleotris Species 0.000 claims abstract description 13
- 241001465754 Metazoa Species 0.000 claims description 13
- 210000003414 extremity Anatomy 0.000 description 11
- 239000007789 gas Substances 0.000 description 6
- 108010066057 cabin-1 Proteins 0.000 description 3
- 210000003141 lower extremity Anatomy 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000001364 upper extremity Anatomy 0.000 description 2
- 241000700159 Rattus Species 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Surgery (AREA)
- Animal Husbandry (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses automatic end-breaking equipment for experimental animals in a hyperbaric chamber, which comprises a base, wherein an electric push rod is fixed at the left end of the surface of the base, an inverted U-shaped bracket is fixed at the right end of the surface of the base, sliding rails are respectively fixed between the electric push rod and the inverted U-shaped bracket, sliding plates are fixed on the two sliding rails, a fixed sleeper plate with an arc-shaped concave part is fixed at the middle position of the right end of the surface of the sliding plate, a first supporting plate and a second supporting plate are respectively fixed at the front side and the rear side of the surface of the sliding plate and positioned at the two sides of the sleeper plate, a first fixing hole and a second fixing hole are formed in the first supporting plate, a third fixing hole and a fourth fixing hole are formed in the second supporting plate, a push rod end of the electric push rod is fixed with the left end of the sliding plate, a driving motor is fixed at the inner side of a top frame of the inverted U-shaped bracket, a driving end of the driving motor is fixed, sliding grooves are formed at the opposite inner sides of two side frames of the inverted U-shaped bracket, two sides of the driving motor are respectively arranged in corresponding sliding grooves, two side frames of the inverted U-shaped bracket are respectively, and a limiting groove of a limiting sliding plate is formed at the surface of the corresponding sliding plate.
Description
Technical Field
The invention relates to the technical field of experimental animal devices, in particular to automatic end breaking equipment for experimental animals in a hyperbaric chamber.
Background
The laboratory workers expose laboratory animals such as rats to the hyperbaric chamber to perform animal experiments, and after the laboratory animals are exposed to the hyperbaric chamber for a period of time, the laboratory animals need to be subjected to a broken-end treatment to obtain head specimens of the laboratory animals. The existing operation mode of the center is as follows: and taking out the experimental animal exposed for a period of time from the hyperbaric chamber by an experimenter, and performing a head breaking operation on the taken out experimental animal by using an animal head breaking device, so as to obtain a head specimen of the experimental animal. The experimental animal is decompressed and taken out from the high-oxygen cabin to perform the head breaking operation so as to obtain the head specimen of the experimental animal, the head specimen of the experimental animal can be influenced, and the actual condition of the head specimen of the experimental animal in the high-pressure environment can not be reduced. The invention designs an automatic end-breaking device for experimental animals in a high-pressure cabin, which is used for carrying out automatic end-breaking operation under high pressure on the experimental animals exposed in the high-pressure cabin to obtain the head specimens of the experimental animals under high pressure.
Disclosure of Invention
Aiming at the problems and the defects existing in the prior art, the invention provides novel automatic end-breaking equipment for experimental animals in a hyperbaric chamber.
The invention solves the technical problems by the following technical proposal:
the invention provides automatic end-breaking equipment for experimental animals in a high-pressure cabin, which is characterized by comprising a high-pressure cabin body, wherein one end of a pressurizing pipeline is fixedly communicated with the high-pressure cabin body, the other end of the pressurizing pipeline penetrates through the high-pressure cabin body and then is externally connected with an air source, a pressurizing electric valve is arranged on the pressurizing pipeline and positioned outside the high-pressure cabin body, one end of a pressure reducing pipeline is fixedly communicated with the high-pressure cabin body, the other end of the pressure reducing pipeline penetrates through the high-pressure cabin body, a pressure reducing electric valve is arranged on the pressure reducing pipeline and positioned outside the high-pressure cabin body, and a pressure sensor is arranged in the high-pressure cabin body.
The utility model provides a laboratory animal head neck pillow, including the base, base detachably fixes in the hyperbaric chamber, the surface left end of base is fixed with electric putter, surface right-hand member and is fixed with the type of falling U support, the surface front and back side of base just is located and is fixed with parallel arrangement's slide rail respectively between electric putter and the type of falling U support, two be fixed with the slide on the slide rail, the surface right-hand member intermediate position department of slide is fixed with the pillow board, set up the arc depressed part that is used for supplying laboratory animal head neck pillow on the pillow board, the surface front and back side of slide just is located the pillow board both sides and is fixed with first backup pad and second backup pad respectively, set up first fixed orifices and the second fixed orifices of wearing to establish the experimental animal one side front and back limb respectively in the first backup pad, set up the third fixed orifices and the fourth fixed orifices of wearing to establish the experimental animal opposite side front and back limb respectively in the second backup pad, the push rod is fixed with the slide on the slide rail, the top of falling U support inboard motor is fixed with the pillow board, the top of type of falling U support is fixed with the motor, the drive frame is fixed with the drive frame is equipped with the drive frame, the drive frame is equipped with the relative drive frame is equipped with the limit slot in the opposite side of sliding board, the both sides are seted up the relative drive frame is equipped with the limit slot.
The high-pressure chamber is provided with a controller outside, and the controller is used for starting the pressure sensor after receiving an experiment operation instruction.
The pressure sensor is used for detecting the pressure value in the ballast body and transmitting the pressure value to the controller, the controller is used for judging the relation between the pressure value and the target pressure value, the pressure-controlled electric valve is controlled to be opened when the pressure value is lower than the target pressure value, gas in the gas source flows into the ballast body through the pressure-controlled electric valve to be pressurized until the pressure value reaches the target pressure value, the pressure-controlled electric valve is closed, the pressure-controlled electric valve is controlled to be opened when the pressure value is higher than the target pressure value, the gas in the ballast body is discharged and depressurized through the pressure-controlled electric valve until the pressure value reaches the target pressure value, and the pressure-controlled electric valve is closed.
The controller is used for judging whether the time of the experimental animal exposed to the target pressure value in the high-pressure chamber reaches the set time, and when the time reaches, the electric push rod is started, the electric push rod pushes the sliding plate to slide on the sliding rail until the sliding plate slides to the limit position in the limit groove, the sleeper plate is arranged below the blade, the driving motor is started, and the driving motor drives the blade to move downwards along the sliding groove and downwards along the right side of the sleeper plate so as to cut off the head and neck of the experimental animal.
The invention has the positive progress effects that:
the invention designs automatic end-breaking equipment for experimental animals in a hyperbaric chamber, which can automatically break the end of the experimental animals exposed in the hyperbaric chamber under high pressure, thereby obtaining head specimens of the experimental animals under high pressure.
Drawings
FIG. 1 is a schematic view of a high pressure tank pressure increasing and reducing pipeline according to a preferred embodiment of the present invention.
Fig. 2 is a schematic structural view of a high pressure chamber internal fracture device according to a preferred embodiment of the present invention.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
As shown in fig. 1 and 2, this embodiment provides an automatic broken end device for experimental animals in a hyperbaric chamber, which comprises a hyperbaric chamber body 1, wherein the hyperbaric chamber body 1 is fixedly communicated with one end of a pressurizing pipeline 2, the other end of the pressurizing pipeline 2 is penetrated with an external air source 3 behind the hyperbaric chamber body 1, a pressurizing electric valve 4 and a pressurizing one-way valve 5 are arranged on the pressurizing pipeline 2 and outside the hyperbaric chamber body 1, one end of a pressure reducing pipeline 6 is fixedly communicated with the hyperbaric chamber body 1, the other end of the pressure reducing pipeline 6 penetrates through the hyperbaric chamber body 1, a pressure reducing one-way valve 7 and a pressure reducing electric valve 8 are arranged on the pressure reducing pipeline 6 and outside the hyperbaric chamber body 1, a pressure sensor 9 is arranged in the hyperbaric chamber body 1, and a controller is arranged outside the hyperbaric chamber body 1.
The high-pressure cabin 1 is internally fixed with a head breaking device, the head breaking device comprises a base 11, the base 11 is detachably fixed in the high-pressure cabin 1, if four corners of the base 11 are fixed in the high-pressure cabin 1 through bolts, an electric push rod 12 is fixed at the left end of the surface of the base 11, an inverted U-shaped bracket 13 is fixed at the right end of the surface of the base 11, sliding rails 14 which are arranged in parallel are respectively fixed between the electric push rod 12 and the inverted U-shaped bracket 13 at the front and back sides of the surface of the base 11, sliding plates 15 are fixed on the two sliding rails 14, a sleeper plate 16 is fixed at the middle position of the right end of the surface of the sliding plate 15, an arc-shaped concave part 17 for the head and neck of an experimental animal is arranged on the sleeper plate 16, a first supporting plate 18 and a second supporting plate 19 are respectively fixed at the front and back sides of the surface of the sliding plate 15, a first fixing hole 20 and a second fixing hole 21 for respectively penetrating the front and back limbs of one side of the experimental animal are arranged on the first supporting plate 18, the second supporting plate 19 is provided with a third fixing hole 22 and a fourth fixing hole 23 which respectively penetrate through the front limb and the rear limb of the other side of the experimental animal, the push rod end of the electric push rod 12 is fixed with the left end of the sliding plate 15, the inner side of the top frame of the inverted U-shaped bracket 13 is fixed with a driving motor 24, the driving motor 24 is an existing motor for realizing linear motion, the driving end of the driving motor 24 is fixed with an inverted U-shaped clamp 25, the inverted U-shaped clamp 25 clamps the top of a blade 26, the clamped position of the inverted U-shaped clamp 25 and the blade 26 is welded, the edge of the blade 26 is downward, the two side frames of the inverted U-shaped bracket 13 are provided with sliding grooves 27 at the opposite inner sides, the two sides of the blade 26 are respectively arranged in the corresponding sliding grooves 27, the two side frames of the inverted U-shaped bracket 13 and the surface corresponding to the sliding plate 15 are provided with limiting grooves 28 for limiting the sliding plate 15, a specimen collection cartridge 29 is placed at the right end of the surface of the base 1 and below the blade 26.
In addition, the binding bands can be fixed on the outer side of the first support plate 18 and respectively beside the first fixing hole 20 and the second fixing hole 21, the binding band beside the first fixing hole 20 can bind the forelimbs of one side of the experimental animal, and the binding band of the second fixing hole 21 can bind the hindlimbs of one side of the experimental animal; also, the binding straps may be fixed to the outer side of the second support plate 19 and located beside the third fixing hole 22 and the fourth fixing hole 23, respectively, the binding straps beside the third fixing hole 22 may bind the forelimbs of the other side of the experimental animal, and the binding straps of the fourth fixing hole 23 may bind the hindlimbs of the other side of the experimental animal.
When the experimental animal is specifically used, the head and neck of the experimental animal is firstly rested on the arc-shaped concave part 17 of the pillow plate 16, the body of the experimental animal is placed on the sliding plate 15, the front and rear limbs on one side of the experimental animal respectively penetrate through the first fixing hole 20 and the second fixing hole 21 on the first supporting plate 18, and the front and rear limbs on the other side of the experimental animal respectively penetrate through the third fixing hole 22 and the fourth fixing hole 23 on the second supporting plate 19, so that the limbs of the experimental animal are fixed. In order to prevent experimental animals from struggling, experimental animal limbs struggle out from corresponding fixed orifices, the limbs of the experimental animals can be further bound by using the binding belts beside each fixed orifice on each supporting plate, so that the limbs of the experimental animals are better and stably fixed. Then the broken end device for fixing the experimental animal is placed in the high-pressure chamber, the broken end device is fixed in the high-pressure chamber 1 through bolts, and then the controller is used for starting the pressure sensor 9 after receiving the experimental operation instruction.
The pressure sensor 9 is used for detecting the pressure value in the high-pressure cabin body 1 and transmitting the pressure value to the controller, the controller is used for judging the relation between the pressure value and the target pressure value, the pressure-reducing electric valve 4 is controlled to be opened when the pressure value is lower than the target pressure value, the gas in the gas source 3 flows into the high-pressure cabin body 1 through the pressure-reducing pipeline 2 to be pressurized until the pressure value reaches the target pressure value, the pressure-reducing electric valve 4 is closed, the pressure-reducing electric valve 8 is controlled to be opened when the pressure value is higher than the target pressure value, the gas in the high-pressure cabin body 1 is exhausted and depressurized through the pressure-reducing pipeline 6 until the pressure value reaches the target pressure value, and the pressure-reducing electric valve 8 is closed, so that the pressure in the high-pressure cabin body 1 is at the target pressure.
The controller is used for starting timing when the pressure value reaches the target pressure value, judging whether the time of exposing the experimental animal to the target pressure value in the hyperbaric chamber 1 reaches the set time, starting the electric push rod 12 when reaching, pushing the slide plate 15 by the electric push rod 12 to slide on the slide rail 14 until the slide plate 15 is limited in the limiting groove 28, placing the sleeper plate 16 below the blade 26 at the moment, placing the head and neck of the experimental animal below the blade 26, starting the driving motor 24 by the controller, driving the blade 26 to move downwards along the chute 27 and downwards along the right side of the sleeper plate 16 so as to cut off the head and neck of the experimental animal, dropping the head specimen of the experimental animal into the specimen collecting box 29, taking out the specimen collecting box 29 from the hyperbaric chamber 1 by staff, and performing slice anatomical analysis on the head specimen of the experimental animal. Therefore, the invention realizes the function of automatically breaking the head of the experimental animal exposed in the high-pressure cabin under high pressure so as to obtain the head specimen of the experimental animal under high pressure.
While specific embodiments of the invention have been described above, it will be appreciated by those skilled in the art that these are by way of example only, and the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the principles and spirit of the invention, but such changes and modifications fall within the scope of the invention.
Claims (6)
1. The automatic end-breaking equipment for the experimental animals in the high-pressure cabin is characterized by comprising a high-pressure cabin body, wherein the high-pressure cabin body is fixedly communicated with one end of a pressurizing pipeline, the other end of the pressurizing pipeline penetrates through the high-pressure cabin body and then is externally connected with an air source, a pressurizing electric valve is arranged on the pressurizing pipeline and positioned outside the high-pressure cabin body, the high-pressure cabin body is fixedly communicated with one end of a pressure reducing pipeline, the other end of the pressure reducing pipeline penetrates through the high-pressure cabin body, a pressure reducing electric valve is arranged on the pressure reducing pipeline and positioned outside the high-pressure cabin body, and a pressure sensor is arranged in the high-pressure cabin body;
the high-pressure chamber is internally fixed with a head breaking device, the head breaking device comprises a base, the base is detachably fixed in the high-pressure chamber, the left end of the surface of the base is fixedly provided with an electric push rod, the right end of the surface of the base is fixedly provided with an inverted U-shaped bracket, the front side and the rear side of the surface of the base are respectively provided with a sliding rail which is arranged in parallel between the electric push rod and the inverted U-shaped bracket, two sliding rails are fixedly provided with sliding plates, a sleeper plate is fixed at the middle position of the right end of the surface of the sliding plate, an arc-shaped concave part for the head and neck of an experimental animal is arranged on the sleeper plate, the front side and the rear side of the surface of the sliding plate are respectively provided with a first supporting plate and a second supporting plate which are respectively positioned at two sides of the sleeper plate, the first support plate is provided with a first fixing hole and a second fixing hole which penetrate through the front limb and the rear limb of one side of the experimental animal respectively, the second support plate is provided with a third fixing hole and a fourth fixing hole which penetrate through the front limb and the rear limb of the other side of the experimental animal respectively, the push rod end of the electric push rod is fixed with the left end of the sliding plate, the inner side of the top frame of the inverted U-shaped support is fixed with a driving motor, the driving end of the driving motor is fixed with a blade, the opposite inner sides of the two side frames of the inverted U-shaped support are provided with sliding grooves, the two sides of the blade are respectively arranged in the corresponding sliding grooves, and the two side frames of the inverted U-shaped support and the surface corresponding to the sliding plate are provided with limiting grooves for limiting the sliding plate;
the pressure chamber is provided with a controller outside, and the controller is used for starting the pressure sensor after receiving an experiment operation instruction;
the pressure sensor is used for detecting the pressure value in the ballast body and transmitting the pressure value to the controller, the controller is used for judging the relation between the pressure value and the target pressure value, controlling the opening of the pressurizing electric valve when the pressure value is lower than the target pressure value, enabling the gas in the gas source to flow into the ballast body through the pressurizing pipeline for pressurizing until the pressure value reaches the target pressure value, closing the pressurizing electric valve, controlling the opening of the depressurizing electric valve when the pressure value is higher than the target pressure value, enabling the gas in the ballast body to be discharged and depressurized through the depressurizing pipeline until the pressure value reaches the target pressure value, and closing the depressurizing electric valve;
the controller is used for judging whether the time of the experimental animal exposed to the target pressure value in the high-pressure chamber reaches the set time, and when the time reaches, the electric push rod is started, the electric push rod pushes the sliding plate to slide on the sliding rail until the sliding plate slides to the limit position in the limit groove, the sleeper plate is arranged below the blade, the driving motor is started, and the driving motor drives the blade to move downwards along the sliding groove and downwards along the right side of the sleeper plate so as to cut off the head and neck of the experimental animal.
2. The automatic end-breaking device for laboratory animals in a high-pressure cabin according to claim 1, wherein a pressurizing one-way valve is arranged on the pressurizing pipeline and outside the high-pressure cabin, and a depressurizing one-way valve is arranged on the depressurizing pipeline and outside the high-pressure cabin.
3. The automatic end-breaking device for laboratory animals in a hyperbaric chamber according to claim 1, wherein the driving end of the driving motor is fixed with an inverted U-shaped clamp, the inverted U-shaped clamp clamps the top of the blade, and the inverted U-shaped clamp is welded with the clamped position of the blade.
4. The automatic end-breaking device for laboratory animals in a hyperbaric chamber according to claim 1, wherein four corners of the base are fixed in the hyperbaric chamber by bolts.
5. The automatic end-breaking device for laboratory animals in hyperbaric chambers according to claim 1, wherein a specimen collection box is placed at the right end of the surface of the base and below the blade.
6. The automatic end-breaking device for laboratory animals in a hyperbaric chamber as set forth in claim 1, wherein the binding belts are fixed on the outer side of the first support plate at the positions beside the first fixing hole and the second fixing hole, respectively, and the binding belts are fixed on the outer side of the second support plate at the positions beside the third fixing hole and the fourth fixing hole, respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310929152.9A CN116807667B (en) | 2023-07-27 | 2023-07-27 | Automatic broken end equipment for experimental animals in hyperbaric chamber |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310929152.9A CN116807667B (en) | 2023-07-27 | 2023-07-27 | Automatic broken end equipment for experimental animals in hyperbaric chamber |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN116807667A true CN116807667A (en) | 2023-09-29 |
| CN116807667B CN116807667B (en) | 2024-02-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310929152.9A Active CN116807667B (en) | 2023-07-27 | 2023-07-27 | Automatic broken end equipment for experimental animals in hyperbaric chamber |
Country Status (1)
| Country | Link |
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| CN (1) | CN116807667B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2036633C1 (en) * | 1993-10-05 | 1995-06-09 | Владимир Васильевич Рыбников | Hyperbaric chamber |
| US20130145506A1 (en) * | 2011-11-18 | 2013-06-06 | Jay B. Dean | Systems And Methods For Performing Microscopy At Hyperbaric Pressures |
| CN111728010A (en) * | 2020-07-02 | 2020-10-02 | 河南中医药大学 | Novel big mouse decapitator |
| CN213249948U (en) * | 2020-06-22 | 2021-05-25 | 天津海河标测技术检测有限公司 | Rodent head cutter |
-
2023
- 2023-07-27 CN CN202310929152.9A patent/CN116807667B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2036633C1 (en) * | 1993-10-05 | 1995-06-09 | Владимир Васильевич Рыбников | Hyperbaric chamber |
| US20130145506A1 (en) * | 2011-11-18 | 2013-06-06 | Jay B. Dean | Systems And Methods For Performing Microscopy At Hyperbaric Pressures |
| CN213249948U (en) * | 2020-06-22 | 2021-05-25 | 天津海河标测技术检测有限公司 | Rodent head cutter |
| CN111728010A (en) * | 2020-07-02 | 2020-10-02 | 河南中医药大学 | Novel big mouse decapitator |
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| Publication number | Publication date |
|---|---|
| CN116807667B (en) | 2024-02-20 |
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