CN116790365A - Microorganism drug sensitivity test card - Google Patents
Microorganism drug sensitivity test card Download PDFInfo
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- CN116790365A CN116790365A CN202310954916.XA CN202310954916A CN116790365A CN 116790365 A CN116790365 A CN 116790365A CN 202310954916 A CN202310954916 A CN 202310954916A CN 116790365 A CN116790365 A CN 116790365A
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- 239000003814 drug Substances 0.000 title claims abstract description 183
- 229940079593 drug Drugs 0.000 title claims abstract description 179
- 244000005700 microbiome Species 0.000 title abstract description 12
- 230000035945 sensitivity Effects 0.000 title description 4
- 239000007788 liquid Substances 0.000 claims abstract description 93
- 230000000903 blocking effect Effects 0.000 claims description 36
- 238000003860 storage Methods 0.000 claims description 26
- 230000000813 microbial effect Effects 0.000 claims description 21
- 230000003139 buffering effect Effects 0.000 claims description 12
- 230000002906 microbiologic effect Effects 0.000 claims description 4
- 230000000979 retarding effect Effects 0.000 abstract description 18
- 238000009792 diffusion process Methods 0.000 abstract description 17
- 238000005452 bending Methods 0.000 description 6
- 230000003749 cleanliness Effects 0.000 description 5
- 238000013016 damping Methods 0.000 description 5
- 238000010276 construction Methods 0.000 description 4
- 238000011534 incubation Methods 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011435 rock Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000012543 microbiological analysis Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
Abstract
The invention relates to the technical field of microorganism tests, in particular to a microorganism drug-sensitive test card, which comprises the following components: a drug sensitive test card body; the main runner is connected with a plurality of branch runners; the drug-sensitive test card comprises a drug-sensitive test card body, a plurality of drug-sensitive test holes, a slow flow passage and a branch flow passage, wherein the drug-sensitive test holes are positioned in the drug-sensitive test card body, and each drug-sensitive test hole is connected with the slow flow passage for preventing liquid from flowing and is connected with the branch flow passage through the slow flow passage. According to the invention, the liquid flow resistance is increased by prolonging the lengths of the retarding hole and the second distribution flow channel, so that liquid diffusion and permeation are avoided between the drug sensitive test holes, the first distribution flow channel and the retarding hole are arranged at right angles, and the second distribution flow channel is arranged at right angles to the retarding hole, so that liquid flow is further hindered; in addition, the first branch flow passage and the second branch flow passage which are arranged at intervals and are in parallel are arranged in each component branch flow passage, so that the possibility of liquid diffusion and permeation between the drug sensitive test holes on two sides of the branch flow passages can be reduced.
Description
Technical Field
The invention relates to the technical field of microorganism tests, in particular to a microorganism drug-sensitive test card.
Background
The drug-sensitive test card is used in a spectrum or other automatic readers, different antibiotics are pre-coated in drug-sensitive test holes of the drug-sensitive test card, a vacuum negative pressure device is used for filling a sample of the drug-sensitive test card with microbial suspension, the sample is placed into an instrument for incubation and culture, and the automatic readers monitor the microbial growth state of the drug-sensitive test holes in the drug-sensitive test card in real time and can be used for analyzing the sensitivity of microorganisms to drugs.
In order to enhance the growth of microorganisms within the test card, the test card is placed in a culture device for culturing. The incubation apparatus has a plurality of rotating turntables for mounting the test cards, which rotate the test cards during incubation without stopping. After incubation is completed, the test card is placed in front of a laser, fluorescent lamp or other illumination source, and spectrum, intensity or other features are generated by the emitted or reflected radiation from the illumination source for microbiological analysis.
Chinese patent CN210030707U discloses a microorganism sample test card, including the main card body of being equipped with inlet and a plurality of reaction hole on the main card body by transparent material preparation, every reaction hole all communicates has the shunt that is used for the feed liquor, every shunt all communicates with the inlet, all is equipped with the observation groove between every reaction hole and every shunt, the degree of depth of observation groove is less than the degree of depth of reaction hole. The test card is made of transparent materials, light can directly penetrate through the main card body, the main card body is provided with a liquid inlet and a plurality of reaction holes, the liquid inlet is communicated with the reaction holes through branch flow passages, observation grooves are formed between each reaction hole and each branch flow passage, when the reaction holes are filled with suspension, the suspension can fill the observation grooves, bubbles are prevented from staying in the observation grooves, and therefore the influence of the bubbles on the form of microorganisms in the suspension by a microscope is avoided. The test card and the test card on the market all have the same technical problems that the drug-sensitive test holes on two sides of each group in the test card share a branch flow passage, and the test card with the structure is easy to cause the phenomenon of mutual diffusion and permeation of liquid between the same group of adjacent drug-sensitive test holes because the turntable drives the test card to rotate continuously in the cultivation process, thereby polluting the drug-sensitive test holes and confusing and distorting the drug-sensitive result.
Disclosure of Invention
The invention aims to provide a microbial drug-sensitive test card, and aims to solve the technical problem that the prior test card is easy to cause liquid interdiffusion and permeation between the same group of adjacent drug-sensitive test holes in the process of using rotation or shaking.
In order to achieve the above object, the present invention provides a microbial drug-sensitive test card, comprising:
the drug-sensitive test card comprises a drug-sensitive test card main body, wherein one end of the drug-sensitive test card main body is provided with a liquid inlet;
the main runner is connected with the liquid inlet and is connected with a plurality of branch runners;
the drug-sensitive test card comprises a drug-sensitive test card body, a plurality of drug-sensitive test holes, a slow flow passage and a branch flow passage, wherein the drug-sensitive test holes are positioned in the drug-sensitive test card body, and each drug-sensitive test hole is connected with the slow flow passage for preventing liquid from flowing and is connected with the branch flow passage through the slow flow passage.
As a further improvement of the invention: the slow flow blocking channel comprises a slow hole, a first distribution flow channel and a second distribution flow channel which are respectively connected with two ends of the slow hole, the other end of the first distribution flow channel is connected with the branch flow channel, and the other end of the second distribution flow channel is connected with the drug sensitive test hole;
the first distribution flow passage is arranged in the direction of the thickness of the drug-sensitive test card main body, and the first distribution flow passage is arranged in the direction of the length of the drug-sensitive test card main body; the part of the flow path of the second distribution flow passage is in a bent structure, and the length extending direction of the part of the flow path of the second distribution flow passage is arranged at right angles to the length extending direction of the buffering hole.
As a further improvement of the invention: the main flow channel is connected with a plurality of groups of branch flow channels, each group of branch flow channels comprises a first branch flow channel and a second branch flow channel which are arranged in parallel at intervals, and the drug sensitive test hole is connected with one side of the first branch flow channel and the opposite side of the second branch flow channel.
As a further improvement of the invention: the main runner comprises a first main runner and a second main runner which are arranged in parallel at intervals, the first branch runner is connected with the first main runner, and the second branch runner is connected with the second main runner.
As a further improvement of the invention: and one end, far away from the branch flow passage, of the drug sensitive test hole is provided with a gas storage part.
As a further improvement of the invention: the gas storage portion is provided with a step.
As a further improvement of the invention: the gas storage portion is provided with an inclined surface.
As a further improvement of the invention: and one end of the drug sensitive test hole, which is far away from the branch flow passage, is connected with a gas storage hole.
As a further improvement of the invention: the main flow channel extends towards the length direction of the drug sensitive test card main body;
the length extension direction of the branch flow channel is perpendicular to the length extension direction of the main flow channel, or the length extension direction of the branch flow channel and the length extension direction of the main flow channel form an included angle.
As a further improvement of the invention: the branch flow passage is provided with a bending section which is positioned close to the main flow passage and is abutted against the liquid inlet.
Compared with the prior art, the invention has the following beneficial effects:
1. according to the invention, the slow flow blocking channel for blocking the flow of liquid is arranged between the branch flow channel and the drug sensitive test hole, so that the mutual diffusion and permeation of liquid between adjacent drug sensitive test holes can be avoided, and the cleanliness of a sample is ensured to be free from pollution; in addition, by prolonging the lengths of the retarding hole and the second distributing runner and arranging the first distributing runner and the retarding hole at right angles, the second distributing runner part flow path and the retarding hole are arranged at right angles, so that the design not only prolongs the liquid flow path to increase the liquid flow resistance, but also simultaneously two right-angle runners can further block the liquid flow, and the difficulty of liquid diffusion and permeation of the adjacent drug sensitive test holes is greatly improved;
2. according to the invention, the first branch flow passage and the second branch flow passage which are arranged at intervals and are in parallel are arranged in each component branch flow passage, so that the possibility of liquid diffusion and permeation between drug sensitive test holes on two sides of the branch flow passages is reduced; and the first main runner and the second main runner which are arranged at intervals and are in parallel are arranged through the main runner, the first branch runner is connected with the first main runner, the second branch runner is connected with the second main runner, and the runners are mutually independent, so that the pollution degree of the drug sensitive test hole can be further reduced.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to the structures shown in these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic structural diagram of a first embodiment of a microbiological drug sensitive test card according to the present invention;
FIG. 2 is a schematic view showing the internal construction of a first embodiment of the microbial drug-sensitive test card of the present invention;
FIG. 3 is a schematic diagram of a second embodiment of a microbiological drug sensitive test card according to the present invention;
FIG. 4 is a schematic view showing the internal structure of a second embodiment of the microbial drug-sensitive test card of the present invention;
FIG. 5 is a schematic view showing the internal construction of a third embodiment of a microbial drug-sensitive test card according to the present invention;
FIG. 6 is a schematic view showing the internal construction of a fourth embodiment of the microbial drug-sensitive test card of the present invention;
FIG. 7 is a schematic view showing the internal construction of a fifth embodiment of the microorganism drug sensitive test card of the present invention.
Reference numerals illustrate:
| reference numerals | Name of the name | Reference numerals | Name of the name |
| 1 | Drug sensitive test card body | 2 | Liquid inlet |
| 3 | Main runner | 4 | Branching flow passage |
| 5 | Drug sensitivity test hole | 6 | Flow-retarding channel |
| 7 | Gas storage hole | 8 | Gas storage part |
| 31 | First main flow passage | 32 | Second main flow passage |
| 41 | First branch flow passage | 42 | Second branch flow passage |
| 61 | First distribution flow channel | 62 | Second distribution flow channel |
| 63 | Buffer hole |
The achievement of the objects, functional features and advantages of the present invention will be further described with reference to the accompanying drawings, in conjunction with the embodiments.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be noted that, if a directional indication (such as up, down, left, right, front, and rear … …) is involved in the embodiment of the present invention, the directional indication is merely used to explain the relative positional relationship, movement condition, etc. between the components in a specific posture, and if the specific posture is changed, the directional indication is correspondingly changed.
In addition, if there is a description of "first", "second", etc. in the embodiments of the present invention, the description of "first", "second", etc. is for descriptive purposes only and is not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include at least one such feature. In addition, if "and/or" and/or "are used throughout, the meaning includes three parallel schemes, for example," a and/or B "including a scheme, or B scheme, or a scheme where a and B are satisfied simultaneously. In addition, the technical solutions of the embodiments may be combined with each other, but it is necessary to base that the technical solutions can be realized by those skilled in the art, and when the technical solutions are contradictory or cannot be realized, the combination of the technical solutions should be considered to be absent and not within the scope of protection claimed in the present invention.
Example 1
Referring to fig. 1-2, the present embodiment provides a microbial drug-sensitive test card, the drug-sensitive test card includes:
the drug-sensitive test card comprises a drug-sensitive test card main body 1, wherein one end of the drug-sensitive test card main body 1 is provided with a liquid inlet 2;
a main runner 3 connected with the liquid inlet 2, wherein the main runner 3 is connected with a plurality of branch runners 4;
the drug-sensitive test card comprises a drug-sensitive test card body 1, a plurality of drug-sensitive test holes 5 positioned in the drug-sensitive test card body 1, wherein each drug-sensitive test hole 5 is connected with a slow flow blocking channel 6 for blocking the flow of liquid and is connected with the branch flow channel 4 through the slow flow blocking channel 6.
Further, the main flow channel 3 extends toward the longitudinal direction of the drug sensitive test card body 1; the length extending direction of the branch flow passage 4 is perpendicular to the length extending direction of the main flow passage 3. In other embodiments, the length extending direction of the branch flow channel 4 and the length extending direction of the main flow channel 3 may also be disposed at an angle. The branch flow passage 4 is provided with a bending section which is positioned close to the main flow passage 3 and is abutted against the liquid inlet 2 so as to slow down the liquid flow speed. The end of the drug sensitive test hole 5, which is far away from the branch flow passage 4, is connected with a gas storage hole 7, and the gas storage hole 7 is used for storing air, so that the drug sensitive test hole 5 can be filled with test liquid.
Further, the slow flow blocking channel 6 comprises a slow flow blocking hole 63, and a first distribution channel 61 and a second distribution channel 62 which are respectively connected with two ends of the slow flow blocking hole 63, wherein the other end of the first distribution channel 61 is connected with the branch channel 4, and the other end of the second distribution channel 62 is connected with the drug sensitive test hole 5;
wherein the buffering hole 63 extends towards the thickness direction of the drug sensitive test card main body 1, and the length extending direction of the first distribution flow channel 61 is arranged at right angles to the length extending direction of the buffering hole 63; a part of the flow path of the second distribution flow path 62 is in a bent structure, and a length extending direction of the part of the flow path of the second distribution flow path 62 is perpendicular to a length extending direction of the damping hole 63.
Specifically, in this embodiment, the liquid inlet 2 is used for injecting a test liquid containing microorganisms, the test liquid flows into each branch flow channel 4 through the main flow channel 3, then flows into each drug sensitive test hole 5 through the slow flow channel 6, and after filling the drug sensitive test hole 5, the next cultivation work is performed. The slow flow passage 6 is used for preventing liquid from flowing, and preventing liquid from diffusing and penetrating between adjacent drug sensitive test holes 5, so that the sample is ensured to be clean and not polluted.
It should be noted that only a straight distribution flow channel is arranged between the drug sensitive test hole 5 and the branch flow channel 4 in the conventional test card, and the test liquid enters the drug sensitive test hole 5 through the distribution flow channel. In the present embodiment, the length of the buffer hole 63 and the second distribution flow channel 62 is extended, so that the liquid flow path is extended to increase the liquid flow resistance; simultaneously, two right-angle flow channels are arranged to further prevent the liquid from flowing, so that the difficulty of liquid diffusion and permeation of the adjacent drug sensitive test holes 5 is greatly improved.
Example two
Referring to fig. 3-4, the present embodiment provides a microbial drug-sensitive test card, the drug-sensitive test card includes:
the drug-sensitive test card comprises a drug-sensitive test card main body 1, wherein one end of the drug-sensitive test card main body 1 is provided with a liquid inlet 2;
a main runner 3 connected with the liquid inlet 2, wherein the main runner 3 is connected with a plurality of branch runners 4;
the drug-sensitive test card comprises a drug-sensitive test card body 1, a plurality of drug-sensitive test holes 5 positioned in the drug-sensitive test card body 1, wherein each drug-sensitive test hole 5 is connected with a slow flow blocking channel 6 for blocking the flow of liquid and is connected with the branch flow channel 4 through the slow flow blocking channel 6.
Further, the main flow channel 3 extends toward the longitudinal direction of the drug sensitive test card body 1; the length extending direction of the branch flow passage 4 is perpendicular to the length extending direction of the main flow passage 3. The branch flow passage 4 is provided with a bending section which is positioned close to the main flow passage 3 and is abutted against the liquid inlet 2 so as to slow down the liquid flow speed. The end of the drug sensitive test hole 5, which is far away from the branch flow passage 4, is connected with a gas storage hole 7, and the gas storage hole 7 is used for storing air, so that the drug sensitive test hole 5 can be filled with test liquid.
Further, the slow flow blocking channel 6 comprises a slow flow blocking hole 63, and a first distribution channel 61 and a second distribution channel 62 which are respectively connected with two ends of the slow flow blocking hole 63, wherein the other end of the first distribution channel 61 is connected with the branch channel 4, and the other end of the second distribution channel 62 is connected with the drug sensitive test hole 5;
wherein the buffering hole 63 extends towards the thickness direction of the drug sensitive test card main body 1, and the length extending direction of the first distribution flow channel 61 is arranged at right angles to the length extending direction of the buffering hole 63; a part of the flow path of the second distribution flow path 62 is in a bent structure, and a length extending direction of the part of the flow path of the second distribution flow path 62 is perpendicular to a length extending direction of the damping hole 63.
Further, the main flow channel 3 is connected to a plurality of sets of branch flow channels 4, each set of branch flow channels 4 includes a first branch flow channel 41 and a second branch flow channel 42 that are spaced apart and are juxtaposed, and the drug sensitive test hole 5 is connected to one side of the first branch flow channel 41 and to the opposite side of the second branch flow channel 42.
In the embodiment, the slow flow passage 6 for slow liquid flow is arranged between the branch flow passage 4 and the drug sensitive test hole 5, so that the mutual diffusion and permeation of liquid between adjacent drug sensitive test holes 5 can be avoided, and the cleanliness of a sample is ensured to be free from pollution; in addition, by prolonging the lengths of the retarding hole 63 and the second distributing runner 62 and arranging the first distributing runner 61 and the retarding hole 63 at right angles, part of the flow path of the second distributing runner 62 and the retarding hole 63 are arranged at right angles, so that the design not only prolongs the liquid flow path to increase the liquid flow resistance, but also simultaneously arranges two right-angle runners to further block the liquid flow, thereby greatly improving the difficulty of liquid diffusion and permeation of the adjacent drug sensitive test holes 5;
in addition, in the present embodiment, by providing the first branch flow channel 41 and the second branch flow channel 42 which are spaced apart and juxtaposed in each group of branch flow channels 4, the possibility of liquid diffusion and permeation between the drug sensitive test holes 5 on both sides of the branch flow channels 4 is reduced.
Example III
Referring to fig. 5, the present embodiment provides a microbial drug-sensitive test card, the drug-sensitive test card comprising:
the drug-sensitive test card comprises a drug-sensitive test card main body 1, wherein one end of the drug-sensitive test card main body 1 is provided with a liquid inlet 2;
a main runner 3 connected with the liquid inlet 2, wherein the main runner 3 is connected with a plurality of branch runners 4;
the drug-sensitive test card comprises a drug-sensitive test card body 1, a plurality of drug-sensitive test holes 5 positioned in the drug-sensitive test card body 1, wherein each drug-sensitive test hole 5 is connected with a slow flow blocking channel 6 for blocking the flow of liquid and is connected with the branch flow channel 4 through the slow flow blocking channel 6.
Further, the main flow channel 3 extends toward the longitudinal direction of the drug sensitive test card body 1; the length extending direction of the branch flow passage 4 is perpendicular to the length extending direction of the main flow passage 3. The branch flow passage 4 is provided with a bending section which is positioned close to the main flow passage 3 and is abutted against the liquid inlet 2 so as to slow down the liquid flow speed. The end of the drug sensitive test hole 5, which is far away from the branch flow passage 4, is connected with a gas storage hole 7, and the gas storage hole 7 is used for storing air, so that the drug sensitive test hole 5 can be filled with test liquid.
Further, the slow flow blocking channel 6 comprises a slow flow blocking hole 63, and a first distribution channel 61 and a second distribution channel 62 which are respectively connected with two ends of the slow flow blocking hole 63, wherein the other end of the first distribution channel 61 is connected with the branch channel 4, and the other end of the second distribution channel 62 is connected with the drug sensitive test hole 5;
wherein the buffering hole 63 extends towards the thickness direction of the drug sensitive test card main body 1, and the length extending direction of the first distribution flow channel 61 is arranged at right angles to the length extending direction of the buffering hole 63; a part of the flow path of the second distribution flow path 62 is in a bent structure, and a length extending direction of the part of the flow path of the second distribution flow path 62 is perpendicular to a length extending direction of the damping hole 63.
Further, the main flow channel 3 is connected to a plurality of sets of branch flow channels 4, each set of branch flow channels 4 includes a first branch flow channel 41 and a second branch flow channel 42 that are spaced apart and are juxtaposed, and the drug sensitive test hole 5 is connected to one side of the first branch flow channel 41 and to the opposite side of the second branch flow channel 42.
Further, the main flow channel 3 includes a first main flow channel 31 and a second main flow channel 32 which are spaced apart and juxtaposed, the first branch flow channel 41 is connected to the first main flow channel 31, and the second branch flow channel 42 is connected to the second main flow channel 32.
In the embodiment, the slow flow passage 6 for slow liquid flow is arranged between the branch flow passage 4 and the drug sensitive test hole 5, so that the mutual diffusion and permeation of liquid between adjacent drug sensitive test holes 5 can be avoided, and the cleanliness of a sample is ensured to be free from pollution; in addition, by prolonging the lengths of the retarding hole 63 and the second distributing runner 62 and arranging the first distributing runner 61 and the retarding hole 63 at right angles, part of the flow path of the second distributing runner 62 and the retarding hole 63 are arranged at right angles, so that the design not only prolongs the liquid flow path to increase the liquid flow resistance, but also simultaneously arranges two right-angle runners to further block the liquid flow, thereby greatly improving the difficulty of liquid diffusion and permeation of the adjacent drug sensitive test holes 5;
in addition, in the present embodiment, by providing the first branch flow channel 41 and the second branch flow channel 42 which are spaced apart and juxtaposed in each group of branch flow channels 4, the possibility of liquid diffusion and permeation between the drug sensitive test holes 5 on both sides of the branch flow channels 4 is reduced; the first main flow channel 31 and the second main flow channel 32 are arranged in parallel at intervals through the main flow channel 3, the first branch flow channel 41 is connected with the first main flow channel 31, the second branch flow channel 42 is connected with the second main flow channel 32, and the flow channels are mutually independent, so that the pollution degree of the drug sensitive test hole 5 can be further reduced.
Example IV
Referring to fig. 6, the present embodiment provides a microbial drug-sensitive test card, the drug-sensitive test card comprising:
the drug-sensitive test card comprises a drug-sensitive test card main body 1, wherein one end of the drug-sensitive test card main body 1 is provided with a liquid inlet 2;
a main runner 3 connected with the liquid inlet 2, wherein the main runner 3 is connected with a plurality of branch runners 4;
the drug-sensitive test card comprises a drug-sensitive test card body 1, a plurality of drug-sensitive test holes 5 positioned in the drug-sensitive test card body 1, wherein each drug-sensitive test hole 5 is connected with a slow flow blocking channel 6 for blocking the flow of liquid and is connected with the branch flow channel 4 through the slow flow blocking channel 6.
Further, the main flow channel 3 extends toward the longitudinal direction of the drug sensitive test card body 1; the length extending direction of the branch flow passage 4 is perpendicular to the length extending direction of the main flow passage 3. The branch flow passage 4 is provided with a bending section which is positioned close to the main flow passage 3 and is abutted against the liquid inlet 2 so as to slow down the liquid flow speed.
Further, the slow flow blocking channel 6 comprises a slow flow blocking hole 63, and a first distribution channel 61 and a second distribution channel 62 which are respectively connected with two ends of the slow flow blocking hole 63, wherein the other end of the first distribution channel 61 is connected with the branch channel 4, and the other end of the second distribution channel 62 is connected with the drug sensitive test hole 5;
wherein the buffering hole 63 extends towards the thickness direction of the drug sensitive test card main body 1, and the length extending direction of the first distribution flow channel 61 is arranged at right angles to the length extending direction of the buffering hole 63; a part of the flow path of the second distribution flow path 62 is in a bent structure, and a length extending direction of the part of the flow path of the second distribution flow path 62 is perpendicular to a length extending direction of the damping hole 63.
Further, a gas storage part 8 is arranged at one end, far away from the branch flow passage 4, in the drug sensitive test hole 5, and the gas storage part 8 is provided with a step.
In the embodiment, the slow flow passage 6 for slow liquid flow is arranged between the branch flow passage 4 and the drug sensitive test hole 5, so that the mutual diffusion and permeation of liquid between adjacent drug sensitive test holes 5 can be avoided, and the cleanliness of a sample is ensured to be free from pollution; in addition, by prolonging the lengths of the retarding hole 63 and the second distributing runner 62 and arranging the first distributing runner 61 and the retarding hole 63 at right angles, part of the flow path of the second distributing runner 62 and the retarding hole 63 are arranged at right angles, so that the design not only prolongs the liquid flow path to increase the liquid flow resistance, but also simultaneously arranges two right-angle runners to further block the liquid flow, thereby greatly improving the difficulty of liquid diffusion and permeation of the adjacent drug sensitive test holes 5;
in addition, in this embodiment, through being provided with gas storage portion 8 in the one end that keeps away from branch runner 4 in the quick test hole 5 of medicine, after quick test card rocks or rotates, gas storage portion 8 can be used to the storage air to make the middle part of quick test hole 5 of medicine can fill up the test liquid, avoid the air to influence the detection of test liquid.
Example five
Referring to fig. 7, the present embodiment provides a microbial drug-sensitive test card, the drug-sensitive test card comprising:
the drug-sensitive test card comprises a drug-sensitive test card main body 1, wherein one end of the drug-sensitive test card main body 1 is provided with a liquid inlet 2;
a main runner 3 connected with the liquid inlet 2, wherein the main runner 3 is connected with a plurality of branch runners 4;
the drug-sensitive test card comprises a drug-sensitive test card body 1, a plurality of drug-sensitive test holes 5 positioned in the drug-sensitive test card body 1, wherein each drug-sensitive test hole 5 is connected with a slow flow blocking channel 6 for blocking the flow of liquid and is connected with the branch flow channel 4 through the slow flow blocking channel 6.
Further, the main flow channel 3 extends toward the longitudinal direction of the drug sensitive test card body 1; the length extending direction of the branch flow passage 4 is perpendicular to the length extending direction of the main flow passage 3. The branch flow passage 4 is provided with a bending section which is positioned close to the main flow passage 3 and is abutted against the liquid inlet 2 so as to slow down the liquid flow speed.
Further, the slow flow blocking channel 6 comprises a slow flow blocking hole 63, and a first distribution channel 61 and a second distribution channel 62 which are respectively connected with two ends of the slow flow blocking hole 63, wherein the other end of the first distribution channel 61 is connected with the branch channel 4, and the other end of the second distribution channel 62 is connected with the drug sensitive test hole 5;
wherein the buffering hole 63 extends towards the thickness direction of the drug sensitive test card main body 1, and the length extending direction of the first distribution flow channel 61 is arranged at right angles to the length extending direction of the buffering hole 63; a part of the flow path of the second distribution flow path 62 is in a bent structure, and a length extending direction of the part of the flow path of the second distribution flow path 62 is perpendicular to a length extending direction of the damping hole 63.
Further, a gas storage part 8 is arranged at one end, far away from the branch flow passage 4, in the drug sensitive test hole 5, and an inclined surface is arranged at the gas storage part 8.
In the embodiment, the slow flow passage 6 for slow liquid flow is arranged between the branch flow passage 4 and the drug sensitive test hole 5, so that the mutual diffusion and permeation of liquid between adjacent drug sensitive test holes 5 can be avoided, and the cleanliness of a sample is ensured to be free from pollution; in addition, by prolonging the lengths of the retarding hole 63 and the second distributing runner 62 and arranging the first distributing runner 61 and the retarding hole 63 at right angles, part of the flow path of the second distributing runner 62 and the retarding hole 63 are arranged at right angles, so that the design not only prolongs the liquid flow path to increase the liquid flow resistance, but also simultaneously arranges two right-angle runners to further block the liquid flow, thereby greatly improving the difficulty of liquid diffusion and permeation of the adjacent drug sensitive test holes 5;
in addition, in this embodiment, through being provided with gas storage portion 8 in the one end that keeps away from branch runner 4 in the quick test hole 5 of medicine, after quick test card rocks or rotates, gas storage portion 8 can be used to the storage air to make the middle part of quick test hole 5 of medicine can fill up the test liquid, avoid the air to influence the detection of test liquid.
The foregoing description is only of the optional embodiments of the present invention, and is not intended to limit the scope of the invention, and all the equivalent structural changes made by the description of the present invention and the accompanying drawings or the direct/indirect application in other related technical fields are included in the scope of the invention.
Claims (10)
1. A microbial drug-sensitive test card comprising:
the drug-sensitive test card comprises a drug-sensitive test card main body, wherein one end of the drug-sensitive test card main body is provided with a liquid inlet;
the main runner is connected with the liquid inlet and is connected with a plurality of branch runners;
the drug-sensitive test card comprises a drug-sensitive test card body, a plurality of drug-sensitive test holes, a slow flow passage and a branch flow passage, wherein the drug-sensitive test holes are positioned in the drug-sensitive test card body, and each drug-sensitive test hole is connected with the slow flow passage for preventing liquid from flowing and is connected with the branch flow passage through the slow flow passage.
2. The microbial drug-sensitive test card according to claim 1, wherein the slow flow blocking channel comprises a slow flow blocking hole, and a first distribution channel and a second distribution channel which are respectively connected with two ends of the slow flow blocking hole, the other end of the first distribution channel is connected with the branch channel, and the other end of the second distribution channel is connected with the drug-sensitive test hole;
the first distribution flow passage is arranged in the direction of the thickness of the drug-sensitive test card main body, and the first distribution flow passage is arranged in the direction of the length of the drug-sensitive test card main body; the part of the flow path of the second distribution flow passage is in a bent structure, and the length extending direction of the part of the flow path of the second distribution flow passage is arranged at right angles to the length extending direction of the buffering hole.
3. The microbiological drug sensitive test card of claim 2 wherein the main flow channel connects a plurality of sets of branch flow channels, each set of branch flow channels includes a first branch flow channel and a second branch flow channel that are spaced apart and in parallel, the drug sensitive test well being connected to one side of the first branch flow channel and to the opposite side of the second branch flow channel.
4. A microbiological drug sensitive test card according to claim 3 wherein the primary flow path comprises first and second spaced apart and juxtaposed primary flow paths, the first branch flow path being connected to the first primary flow path and the second branch flow path being connected to the second primary flow path.
5. The microbial drug-sensitive test card according to claim 2, wherein a gas storage part is arranged at one end of the drug-sensitive test hole far away from the branch flow passage.
6. The microbial drug sensitive test card of claim 5 wherein the gas storage portion is provided with a step.
7. The microbial drug sensitive test card according to claim 5, wherein the gas storage portion is provided with an inclined surface.
8. The microbial drug-sensitive test card according to any one of claims 1 to 4, wherein a gas storage hole is connected to an end of the drug-sensitive test hole away from the branch flow passage.
9. The microbial drug-sensitive test card of claim 1 wherein the primary flow channel extends in a longitudinal direction of the drug-sensitive test card body;
the length extension direction of the branch flow channel is perpendicular to the length extension direction of the main flow channel, or the length extension direction of the branch flow channel and the length extension direction of the main flow channel form an included angle.
10. The microbial drug sensitive test card according to claim 9, wherein the branch flow channel is provided with a curved section located close to the main flow channel and abutting the liquid inlet.
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