CN116773664A - Blood simulation phantom performance detection method and device - Google Patents
Blood simulation phantom performance detection method and device Download PDFInfo
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- CN116773664A CN116773664A CN202310714105.2A CN202310714105A CN116773664A CN 116773664 A CN116773664 A CN 116773664A CN 202310714105 A CN202310714105 A CN 202310714105A CN 116773664 A CN116773664 A CN 116773664A
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Abstract
The invention discloses a blood simulation body model performance detection method, which belongs to the field of medical instrument quality detection, wherein laser with frequency f is emitted to blood simulation tube by adopting a laser transducer to irradiate on blood simulation tube with speed c, the blood simulation tube reflects the laser to the laser transducer, the reflected laser frequency f 'received by the laser transducer is calculated by calculating the laser frequency f' received by the blood simulation tube, thereby calculating Doppler frequency shift quantity of the blood simulation body model, and the calculated Doppler frequency shift quantity f d And comparing the Doppler frequency shift amount with the theoretical value of the simulated blood model, thereby evaluating the performance of the simulated blood model. The invention further comprises a blood simulation body model performance detection device for implementing the blood simulation body model performance detection method.
Description
Technical Field
The invention relates to the field of medical instrument quality detection, in particular to a blood simulation phantom performance detection method and device.
Background
The successful application of the doppler principle in ultrasonic diagnostic techniques is one of the great advances made by human beings in the medical and instrumental engineering fields in the 20 th century. The phenomenon of ultrasonic doppler shift is a physical effect due to the relative motion of the sound source and the receiver or echo target (reflector, scatterer). The working modes of the current clinically used equipment are divided into three types of Continuous Wave Doppler (CWD), pulse Wave Doppler (PWD) and color Doppler blood flow imaging (CFM), the echo targets comprise red blood cells, cardiac muscles, blood vessel walls and tissues close to moving organs, and the information presentation and provision modes comprise three types of Doppler frequency spectrums, color blood flow diagrams and audible sound signals. In specific products, the domestic general name of color Doppler ultrasound, namely the foreign name of three-function instrument, is integrated with a plurality of information forms such as two-dimensional (2D) gray scale imaging, doppler color blood flow diagrams, doppler energy diagrams, continuous and pulse wave Doppler frequency spectrums, doppler sound signals and the like; the foreign double instrument is called as high-grade black and white super with pulse Doppler frequency spectrum and audible sound signal output; the transcranial Doppler blood flow instrument and the Doppler fetal umbilical blood flow instrument only provide frequency spectrums and sounds corresponding to blood flow velocity; fetal heart rate (tone) meters acoustically monitor fetal heart rate; in recent years, fetal monitors on the market integrate umbilical blood flow and heart rate detection.
As with other medical ultrasonic instruments, in order to ensure the safety and effectiveness of the Doppler system in clinical application, the Doppler system performance must be scientifically detected and objectively evaluated in links such as product development, production, marketing approval, purchase acceptance, periodic verification, and comparison of similar products.
At present, the performance of Doppler equipment is detected by a blood-simulating body model commonly, but the performance of the blood-simulating body model is not provided with a specific detection method and equipment, and when the Doppler equipment is detected by the blood-simulating body model with unqualified performance, the detection result is low in accuracy.
Disclosure of Invention
In order to overcome the defects of the prior art, one of the purposes of the invention is to provide a blood-simulating body model performance detection method which can detect the performance of the blood-simulating body model and improve the detection accuracy of Doppler equipment.
In order to overcome the defects of the prior art, the second aim of the invention is to provide a blood-simulating body model performance detection device which can detect the performance of the blood-simulating body model and improve the detection accuracy of Doppler equipment.
One of the purposes of the invention is realized by adopting the following technical scheme:
a blood simulation body model performance detection method comprises the following steps:
s1, enabling blood to enter a blood simulating vessel of a blood simulating body model at a speed v;
s2, the laser energy converter emits laser with the frequency f to irradiate the blood imitation in the blood imitation tube, the speed of the laser in the blood imitation tube is c, and the frequency of the laser received by the blood imitation tube isBeta is the included angle between the connecting line of the blood imitation and the laser transducer after moving and the speed direction;
s3, simulating blood to reflect laser to the laser transducer, wherein the frequency of the reflected laser received by the laser transducer is
S4, calculating Doppler frequency shift f of the simulated blood phantom d ＝f″-f；
S5, calculating Doppler frequency shift quantity f d And comparing the simulated blood model Doppler frequency shift with a theoretical value of the simulated blood model Doppler frequency shift, and judging the simulated blood model performance.
Further, in step S1, the blood-mimicking body is driven by a pump to enter a blood-mimicking body vessel of a blood-mimicking phantom at a speed v, and the speed of the blood-mimicking body is monitored by a flow meter.
Further, the blood-imitating vessel forms an angle of 45 degrees with the horizontal plane, beta is 45 degrees,
further, in step S5, when the calculated Doppler shift amount f d And blood-like bodyThe difference value of the theoretical values of the mode Doppler frequency shift quantity is less than or equal to 5 percent, and the performance of the simulated blood body model is judged to be qualified; when Doppler shift quantity f d And judging that the performance of the simulated blood body model is unqualified, wherein the difference value between the simulated blood body model and the theoretical value of the Doppler frequency shift quantity of the simulated blood body model is more than 5%.
Furthermore, the blood-imitating body model is filled with blood-imitating tissues.
The second purpose of the invention is realized by adopting the following technical scheme:
the utility model provides a imitative blood body model performance detection device for implementing above-mentioned imitative blood body model performance detection method, includes holding vessel, driving pump, laser energy converter and imitative blood vessel, the holding vessel driving pump and imitative blood body model pass through imitative blood vessel intercommunication, imitative blood vessel part is located imitative blood body model and form the contained angle with the horizontal plane, driving pump drive imitative blood in the holding vessel gets into imitative blood body model along imitative blood vessel at preset speed, laser energy converter launches laser to imitative blood vessel in the imitative blood body model, and the laser that receives imitative blood reflection.
Further, the blood flow meter is mounted on the blood-simulating tube, and the speed of the blood-simulating tube is monitored.
Further, the blood-imitating vessel is made of polytetrafluoroethylene or polyethylene.
Further, the blood simulation tube in the blood simulation phantom forms an included angle of 45 degrees with the horizontal plane.
Further, the laser transducer is positioned above the blood-simulating phantom.
Compared with the prior art, the blood simulation body model performance detection method provided by the invention has the advantages that the laser energy converter is adopted to emit laser with the frequency f to irradiate the blood simulation tube at the speed c, the blood simulation reflects the laser to the laser energy converter, the reflected laser frequency f 'received by the laser energy converter is calculated by calculating the laser frequency f' received by the blood simulation, so that the Doppler frequency shift quantity of the blood simulation body model is calculated, and the calculated Doppler frequency shift quantity f is calculated d And comparing the Doppler frequency shift amount with the theoretical value of the simulated blood model, thereby evaluating the performance of the simulated blood model.
Drawings
FIG. 1 is a flow chart of a method for detecting blood simulation performance of the present invention;
fig. 2 is a schematic structural diagram of a blood simulation performance detecting device of the present invention.
In the figure: 10. a storage tank; 20. driving a pump; 30. a flow meter; 40. imitation blood vessel; 50. a laser transducer; 201. simulating a blood phantom; 200. blood tissue was simulated.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It will be understood that when an element is referred to as being "fixed to" another element, it can be directly on the other element or be present as another intermediate element through which the element is fixed. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. When an element is referred to as being "disposed on" another element, it can be directly on the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like are used herein for illustrative purposes only.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
FIG. 1 is a flow chart of the blood-simulating body model performance detection method of the invention, which comprises the following steps:
s1, enabling blood to enter a blood simulating vessel of a blood simulating body model at a speed v;
s2, the laser energy converter emits laser with the frequency f to irradiate the blood imitation in the blood imitation tube, the speed of the laser in the blood imitation tube is c, and the frequency of the laser received by the blood imitation tube is
S3, simulating blood to reflect laser to the laser transducer, wherein the frequency of the reflected laser received by the laser transducer isBeta is the included angle between the connecting line of the moved blood imitation and the laser transducer and the speed direction, and beta is the included angle between the connecting line of the moved blood imitation and the laser transducer and the speed direction;
s4, calculating Doppler frequency shift f of the simulated blood phantom d ＝f″-f；
S5, calculating Doppler frequency shift quantity f d And comparing the simulated blood model Doppler frequency shift with a theoretical value of the simulated blood model Doppler frequency shift, and judging the simulated blood model performance.
Specifically, in step S1, the blood-mimicking body is driven by a pump to enter a blood-mimicking body vessel at a speed v, the speed of the blood-mimicking body is monitored by a flow meter, and the flow rate detected by the flow meter ranges from 1.6ml/S to 16ml/S. The detection temperature was 25 ℃. The blood-like particle concentration range reaches the hematocrit level (about 40%) of normal people. The blood-imitating vessel is made of polytetrafluoroethylene or polyethylene, and is attached to the human body blood vessel. The blood simulation tube forms an angle of 45 degrees with the horizontal plane, the beta is 45 degrees,in step S5, when the calculated Doppler shift amount f d The difference value between the simulated blood model Doppler frequency shift quantity and the theoretical value of the simulated blood model Doppler frequency shift quantity is less than or equal to 5 percent, and the simulated blood model performance is judged to be qualified; when Doppler shift quantity f d And judging that the performance of the simulated blood body model is unqualified, wherein the difference value between the simulated blood body model and the theoretical value of the Doppler frequency shift quantity of the simulated blood body model is more than 5%.
With continued reference to fig. 2, the present invention further relates to a blood-simulating body model performance detecting device for implementing the above-mentioned blood-simulating body model performance detecting method, and the blood-simulating body model performance detecting device is used for detecting the blood-simulating body model 201.
The blood-simulating tissue 200 is filled in the blood-simulating body model 201, specifically, the structure of the blood-simulating body model 201 is shown in a patent with the name of an ultrasonic Doppler blood-simulating body model with publication number CN109431541A, an outer shell of the blood-simulating body model 201 adopts an acrylic plate, and a long bottom plate is provided with two holes, and is sealed by a vacuum sealing rubber to be used for filling tissue-simulating materials. The blood-imitating tissue 200 is made of water-based gel-based polymer composite material. The upper panel has an aperture for mounting the laser transducer. The laser transducer functions to emit laser light and to receive scattered laser light. The two blood-imitating vessels are parallel to each other and form an angle of 45 degrees with the ground. The inner diameters of the two blood simulation vessels are 8mm, the wall thickness is 1.65mm,4mm and the wall thickness is 0.8mm respectively. A gradual change channel is arranged between the two pipes, and a pagoda threaded joint is used.
The blood simulation performance detection device comprises a storage tank 10, a driving pump 20, a flowmeter 30, a blood simulation tube 40 and a laser transducer 50.
The reservoir 10 is used to store blood-like particles in a concentration range up to the level of hematocrit (about 40%) of a normal human.
The drive pump 20 is used to drive the flow of blood-mimicking fluid in the reservoir 10 along the blood-mimicking vessel 40 at a speed v. The drive pump 20 communicates with the reservoir 10 through the blood-mimicking vessel 40.
The flow meter 30 is mounted on the blood-mimicking tube 40 for monitoring the speed of the blood-mimicking tube, and the flow rate detected by the flow meter ranges from 1.6ml/s to 16ml/s.
The blood-mimicking vessel 40 is used to connect the reservoir 10 and drive the pump 20, and the blood-mimicking vessel 40 penetrates through the blood-mimicking phantom 201. The blood-mimicking tube 40 in the blood-mimicking phantom 201 forms an angle with the horizontal plane. In this embodiment, the blood simulation 40 in the blood simulation phantom 201 is 45 degrees from the horizontal. The blood-imitating vessel 40 is made of polytetrafluoroethylene or polyethylene, and is attached to the human body blood vessel.
The laser transducer 50 is capable of emitting laser light having a wavelength λ and a frequency f. The laser transducer 50 is located at the upper part of the blood-simulating phantom 201, and the laser emitted by the laser transducer 50 irradiates the blood-simulating body moving in the blood-simulating tube 40 inside the blood-simulating phantom 201, and the blood-simulating body reflects the laser to the laser transducer 50.
When the blood-simulating body model performance detecting device is used, the pump 20 is driven to drive the blood-simulating body in the storage tank 10 to flow along the blood-simulating tube 40 at the speed v and enter the blood-simulating tube 40 in the blood-simulating body model 201. The flow meter 30 monitors the speed of the simulated blood. The laser transducer 50 emits laser with frequency f, the speed of the laser in the simulated blood is c, and the frequency of the laser received by the simulated blood isThe blood-like laser is reflected to the laser transducer 50, and the reflected laser frequency received by the laser transducer 50 is +.>Beta is the angle between the line connecting the blood-like substance after movement and the laser transducer 50 and the direction of velocity v. Calculating Doppler frequency shift f of blood simulation phantom 201 d =f "-f, the calculated doppler shift amount f d And comparing the Doppler frequency shift amount of the simulated blood phantom 201 with a theoretical value, and judging the performance of the simulated blood phantom 201.
The foregoing examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that, for those skilled in the art, it is possible to make several modifications and improvements without departing from the concept of the present invention, which are equivalent to the above embodiments according to the essential technology of the present invention, and these are all included in the protection scope of the present invention.
Claims (10)
1. The blood simulation phantom performance detection method is characterized by comprising the following steps of:
s1, enabling blood to enter a blood simulating vessel of a blood simulating body model at a speed v;
s2, the laser transducer emits laser with the frequency f to irradiate the blood imitation in the blood imitation tube, and the laser is in the blood imitation tubeIs c, the laser frequency received by the simulated blood isBeta is the included angle between the connecting line of the blood imitation and the laser transducer after moving and the speed direction;
s3, simulating blood to reflect laser to the laser transducer, wherein the frequency of the reflected laser received by the laser transducer is
S4, calculating Doppler frequency shift f of the simulated blood phantom d ＝f″-f；
S5, calculating Doppler frequency shift quantity f d And comparing the simulated blood model Doppler frequency shift with a theoretical value of the simulated blood model Doppler frequency shift, and judging the simulated blood model performance.
2. The method for detecting the performance of a blood simulation according to claim 1, wherein: in step S1, the blood-mimicking body is driven by a pump at a speed v into a blood-mimicking body vessel of a blood-mimicking phantom, and the speed of the blood-mimicking body is monitored by a flow meter.
3. The method for detecting the performance of a blood simulation according to claim 1, wherein: when the blood simulation tube forms an angle of 45 degrees with the horizontal plane, beta is 45 degrees,
4. the method for detecting the performance of a blood simulation according to claim 1, wherein: in step S5, when the calculated Doppler shift amount f d The difference value between the simulated blood model Doppler frequency shift quantity and the theoretical value of the simulated blood model Doppler frequency shift quantity is less than or equal to 5 percent, and the simulated blood model performance is judged to be qualified; when Doppler shift quantity f d And judging that the performance of the simulated blood body model is unqualified, wherein the difference value between the simulated blood body model and the theoretical value of the Doppler frequency shift quantity of the simulated blood body model is more than 5%.
5. The method for detecting the performance of a blood simulation according to claim 1, wherein: and filling blood-imitating tissues into the blood-imitating body mould.
6. A blood simulation performance detection apparatus for implementing the blood simulation performance detection method according to any one of claims 1 to 5, characterized in that: including holding vessel, driving pump, laser energy converter and imitative blood vessel, the holding vessel driving pump and imitative blood phantom pass through imitative blood vessel intercommunication, imitative blood vessel part is located imitative blood phantom in and form the contained angle with the horizontal plane, driving pump drive imitative blood in the holding vessel gets into imitative blood phantom along imitative blood vessel with predetermineeing the speed, laser energy converter emits laser to imitative blood vessel in the imitative blood phantom, and receives imitative blood reflection's laser.
7. The blood simulation performance test apparatus of claim 6, wherein: the blood-simulating device further comprises a flowmeter, wherein the flowmeter is arranged on the blood-simulating tube, and the speed of the blood-simulating tube is monitored.
8. The blood simulation performance test apparatus of claim 6, wherein: the blood-imitating vessel is made of polytetrafluoroethylene or polyethylene.
9. The blood simulation performance test apparatus of claim 6, wherein: the blood simulating tube in the blood simulating body model forms an included angle of 45 degrees with the horizontal plane.
10. The blood simulation performance test apparatus of claim 6, wherein: the laser transducer is positioned above the simulated blood phantom.
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