CN116713132A - Centrifuge control method, apparatus, device, and storage medium - Google Patents
Centrifuge control method, apparatus, device, and storage medium Download PDFInfo
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- CN116713132A CN116713132A CN202310351412.9A CN202310351412A CN116713132A CN 116713132 A CN116713132 A CN 116713132A CN 202310351412 A CN202310351412 A CN 202310351412A CN 116713132 A CN116713132 A CN 116713132A
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- 238000000034 method Methods 0.000 title claims abstract description 61
- 238000005119 centrifugation Methods 0.000 claims abstract description 40
- 230000009467 reduction Effects 0.000 claims abstract description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 16
- 238000004590 computer program Methods 0.000 claims description 16
- 230000001133 acceleration Effects 0.000 claims description 12
- 239000011324 bead Substances 0.000 claims description 9
- 150000007523 nucleic acids Chemical class 0.000 claims description 9
- 102000039446 nucleic acids Human genes 0.000 claims description 9
- 108020004707 nucleic acids Proteins 0.000 claims description 9
- 239000000377 silicon dioxide Substances 0.000 claims description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 238000004891 communication Methods 0.000 description 10
- 238000010586 diagram Methods 0.000 description 10
- 230000006870 function Effects 0.000 description 8
- 238000012545 processing Methods 0.000 description 6
- 238000000605 extraction Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- 230000002159 abnormal effect Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001953 sensory effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000003491 array Methods 0.000 description 1
- 238000013473 artificial intelligence Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 238000010801 machine learning Methods 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 238000011946 reduction process Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B15/00—Other accessories for centrifuges
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Abstract
The invention discloses a centrifuge control method, a centrifuge control device, centrifuge control equipment and a storage medium. The method comprises the following steps: under the condition that a centrifugation ending signal is detected, acquiring a current centrifugation duration of the centrifugal machine and a first mechanical time constant corresponding to a sample type of a current target sample; and controlling the centrifugal machine to execute the speed reduction operation by adopting a first exponential rotation speed control algorithm based on the current rotation speed of the centrifugal machine, the first mechanical time constant and the current centrifugal time length until the rotation speed of the centrifugal machine is zero. The method solves the problem that the existing centrifuge control method is not smooth in deceleration stopping, achieves stable deceleration of the centrifuge, and improves the centrifugal effect.
Description
Technical Field
The present invention relates to the field of centrifuges, and in particular, to a centrifuge control method, apparatus, device, and storage medium.
Background
The silica bead method for extracting nucleic acid can amplify with beads, is suitable for most of complex forensic samples, and is an important method for extracting nucleic acid in the forensic field.
The existing centrifuge control method for extracting nucleic acid by a silica bead method is difficult to separate silica beads from nucleic acid due to unstable speed of a deceleration stage of a centrifuge. In summary, the conventional centrifuge control method has the problem that the deceleration stop is not smooth.
Disclosure of Invention
The invention provides a centrifuge control method, a device, equipment and a storage medium, which are used for solving the problem that the deceleration stop is not smooth in the existing centrifuge control method.
According to an aspect of the present invention, there is provided a centrifuge control method including:
under the condition that a centrifugation ending signal is detected, acquiring a current centrifugation duration of the centrifugal machine and a first mechanical time constant corresponding to a sample type of a current target sample;
and controlling the centrifugal machine to execute the speed reduction operation by adopting a first exponential rotation speed control algorithm based on the current rotation speed of the centrifugal machine, the first mechanical time constant and the current centrifugal time length until the rotation speed of the centrifugal machine is zero.
According to another aspect of the present invention, there is provided a centrifuge control device including:
the centrifugal machine deceleration parameter acquisition module is used for acquiring the current centrifugal time length of the centrifugal machine and a first mechanical time constant corresponding to the sample type of the current target sample under the condition that a centrifugal end signal is detected;
and the centrifugal machine speed reducing module is used for controlling the centrifugal machine to execute speed reducing operation by adopting a first exponential speed control algorithm based on the current speed of the centrifugal machine, a first mechanical time constant and the current centrifugal time length until the speed of the centrifugal machine is zero.
According to another aspect of the present invention, there is provided an electronic device including:
at least one processor; and
a memory communicatively coupled to the at least one processor; wherein,,
the memory stores a computer program executable by the at least one processor to enable the at least one processor to perform the centrifuge control method of any of the embodiments of the present invention.
According to another aspect of the present invention, there is provided a computer readable storage medium storing computer instructions for causing a processor to execute a centrifuge control method of any of the embodiments of the present invention.
According to the technical scheme of the centrifuge control method provided by the embodiment of the invention, the rotating speed of the centrifuge in the deceleration stage is controlled based on the index, so that the stable deceleration of the centrifuge is realized, and the centrifugal effect is improved.
It should be understood that the description in this section is not intended to identify key or critical features of the embodiments of the invention or to delineate the scope of the invention. Other features of the present invention will become apparent from the description that follows.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is apparent that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a flow chart of a centrifuge control method provided by an embodiment of the present invention;
FIG. 2 is a flow chart of another centrifuge control method provided by an embodiment of the present invention;
FIG. 3A is a block diagram of a first centrifuge control device according to an embodiment of the present invention;
FIG. 3B is a block diagram of a second centrifuge control device according to an embodiment of the present invention;
FIG. 3C is a block diagram of a third centrifuge control device according to an embodiment of the present invention;
FIG. 3D is a block diagram of a fourth centrifuge control device according to an embodiment of the present invention;
FIG. 3E is a block diagram of a fifth centrifuge control device according to an embodiment of the present invention;
FIG. 3F is a block diagram of a sixth centrifuge control device according to an embodiment of the present invention;
fig. 4 is a block diagram of an electronic device according to an embodiment of the present invention.
Detailed Description
In order that those skilled in the art will better understand the present invention, a technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in which it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present invention without making any inventive effort, shall fall within the scope of the present invention.
It should be noted that the terms "first" and "second" and the like in the description and the claims of the present invention and the above drawings are used for distinguishing between similar objects and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used may be interchanged where appropriate such that the embodiments of the invention described herein may be implemented in sequences other than those illustrated or otherwise described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
Fig. 1 is a flowchart of a centrifuge control method according to an embodiment of the present invention, where the embodiment is applicable to a scenario of centrifuge control for nucleic acid extraction based on a silica bead method, and may be executed by a centrifuge control device, where the centrifuge control device may be implemented in a hardware and/or software form and configured in a processor of an electronic device.
As shown in fig. 1, the centrifuge control method includes the steps of:
s110, under the condition that a centrifugation ending signal is detected, acquiring a current centrifugation duration of the centrifugal machine and a first mechanical time constant corresponding to a sample type of a current target sample.
The first mechanical time constant is the time required for the motor of the centrifuge to reach 63.2% of the nominal rotational speed at a nominal voltage, which may be, for example, an empty load.
The current centrifugal time length is the time length from the starting time of the motor to the current time corresponding to the current centrifugal process of the centrifugal machine.
It will be appreciated that different sample types have corresponding set centrifugation speeds and first set centrifugation durations. In a specific embodiment, a corresponding relation between various sample types and centrifugal parameters is pre-established, and the centrifugal parameters corresponding to the current centrifugal sample are determined according to the corresponding relation, wherein the centrifugal parameters comprise parameters such as a set centrifugal speed, a first set centrifugal time length, a first mechanical time constant and the like.
Further, before the first mechanical time constant corresponding to the current centrifugation duration of the centrifuge and the sample type of the current target sample is obtained under the condition that the centrifugation ending signal is detected, the method further comprises:
step a1, obtaining a first set centrifugal time length.
And a2, controlling the centrifugal machine to operate at a set centrifugal speed for a first set centrifugal time.
Specifically, calculating at the moment when the rotational speed of the centrifugal machine reaches the set centrifugal speed, controlling the centrifugal machine to operate at the set centrifugal speed for a first set centrifugal time length, and generating a corresponding centrifugal ending signal; and under the condition that the centrifugation ending signal is detected, acquiring the current centrifugation duration of the centrifugal machine and a first mechanical time constant corresponding to the sample type of the current target sample.
S120, based on the current rotation speed of the centrifugal machine, the first mechanical time constant and the current centrifugal time length, the centrifugal machine is controlled to execute the speed reduction operation by adopting a first exponential rotation speed control algorithm until the rotation speed of the centrifugal machine is zero.
The first exponential rotation speed control algorithm controls the rotation speed of the centrifugal machine in the form of an exponential function.
In a specific embodiment, the first exponential rotational speed control algorithm is represented by the following formula:
wherein v is 1 (t) is the rotation speed of the centrifugal machine at the moment t, V m For the current rotation speed of the centrifugal machine (namely, the set centrifugal speed), T m T is the moment corresponding to the current centrifugal time length e At the time point when the rotational speed is reduced to 0 in the centrifuge, τ is the first mechanical time constant. An e negative exponential function in the first exponential rotation speed control algorithm gradually reduces the absolute value of the slope of the e negative exponential function along with the increase of the centrifugal time length, and the rotation speed v of the centrifugal machine 1 (t) gradually and gradually changes until the rotation speed of the centrifugal machine is 0.
According to the technical scheme, the centrifugal machine speed reduction process is controlled according to the first exponential rotation speed control algorithm, the problem that the speed reduction is not smooth in stopping in the existing centrifugal machine control method is solved, stable speed reduction of the centrifugal machine is achieved, and the centrifugal effect is improved.
Fig. 2 is a flowchart of another centrifuge control method according to an embodiment of the present invention, where the embodiment is applicable to a scenario of centrifuge control for nucleic acid extraction based on a silica bead method, and is particularly applicable to a scenario of plate-type centrifuge control for nucleic acid extraction based on a silica bead method, and the embodiment is the same inventive concept as the centrifuge control method in the above embodiment, and on the basis of the above embodiment, the following steps are added before acquiring a current centrifugation duration of a centrifuge and a first mechanical time constant corresponding to a sample type of a current target sample under the condition that a centrifugation end signal is detected: under the condition that a centrifugal signal is detected, acquiring a set centrifugal speed and a second mechanical time constant corresponding to the sample type of the current target sample; and controlling the centrifugal machine to execute acceleration operation by adopting a second index rotating speed control algorithm based on the set centrifugal speed and the second mechanical time constant until the rotating speed of the centrifugal machine reaches the set centrifugal speed.
As shown in fig. 2, the centrifuge control method includes:
s2101, under the condition that a centrifugal signal is detected, acquiring a set centrifugal speed and a second mechanical time constant corresponding to the sample type of the current target sample.
In one embodiment, the second mechanical time constant is the same as the first mechanical time constant, and in particular, the acceleration and deceleration phases of the centrifuge are controlled based on the same mechanical time constant.
Setting the centrifugal speed as the centrifugal speed required by the centrifugation for the sample type of the current target sample.
In one embodiment, before acquiring the set centrifugal speed and the second mechanical time constant corresponding to the sample type of the current target sample in the case of detecting the centrifugal signal, acquiring the sample identification of the current target sample, and determining the sample type of the current target sample according to the corresponding relationship between the pre-created sample identification and the sample type.
Specifically, corresponding sample identifiers are set for various sample types in advance, corresponding modules corresponding to radio frequency identification (Radio Frequency Identification, RFID), bluetooth or near field communication (Near Field Communication, NFC) and other wireless transmission technologies can be set in the centrifuge, corresponding modules are set on the centrifuge tube correspondingly, corresponding sample identifiers are obtained through the wireless transmission technology, and then the sample type of the current target sample is determined according to the corresponding relation between the pre-established sample identifiers and the sample types.
Further, before detecting the centrifugal signal, it includes:
and b1, controlling the centrifugal machine to perform self-checking to obtain a self-checking result.
Specifically, before centrifugation, the centrifuge is required to perform self-test, and whether the centrifuge is abnormal or not is determined, so that a self-test result is obtained. Exemplary, checks are made as to whether the centrifuge is balancing, whether the cover is closed, whether the modules are functioning abnormally, etc.
And b2, displaying prompt information corresponding to the self-checking result.
Specifically, according to each self-checking result, corresponding prompt information is set for prompting the user that each module is abnormal/normal. The prompt information may be any form of sensory feedback (e.g., visual feedback and/or auditory feedback, etc.). For example, for the situation that the centrifuge is not trimmed as a result of the self-checking, a corresponding prompt tone and/or error prompt is set, and the corresponding error prompt is displayed through a display device.
Further, under the condition that the centrifugal signal is detected, acquiring the set centrifugal speed and the second mechanical time constant corresponding to the sample type of the current target sample, and simultaneously, further including:
step c1, obtaining a second set centrifugal time length corresponding to the sample type of the current target sample and the current centrifugal time length of the centrifugal machine.
The second set centrifugation time is the sum of time required by the centrifugal machine to execute centrifugation operation on any sample, and specifically is the sum of acceleration time length of the centrifugal machine, the first set centrifugation time length and deceleration time length of the centrifugal machine.
And c2, determining the countdown according to the second set centrifugal time length and the current centrifugal time length.
And taking the difference value between the second set centrifugal time length and the current centrifugal time length as a countdown.
And c3, displaying countdown.
Optionally, the countdown is displayed in seconds/minute by visual feedback and/or auditory feedback.
S2102, based on the set centrifugal speed and the second mechanical time constant, the centrifugal machine is controlled to execute acceleration operation by adopting a second index rotating speed control algorithm until the rotating speed of the centrifugal machine reaches the set centrifugal speed.
In a specific embodiment, the first mechanical time constant is the same as the second mechanical time constant.
Wherein, the second index rotation speed control algorithm is represented by the following formula:
wherein v is 2 (t) is the rotation speed of the centrifugal machine at the moment t, V m To set the centrifugal speed, T b The centrifugal speed is set at the moment when the rotational speed of the centrifugal machine reaches the set centrifugal speed. An e negative exponential function in the second exponential rotation speed control algorithm gradually reduces the absolute value of the slope of the e negative exponential function along with the increase of the current centrifugal time length, and the rotation speed v of the centrifugal machine 2 (T) gradually and gradually changes until the rotation speed of the centrifugal machine reaches the set centrifugal speed, and the centrifugal machine is realized in the centrifugal time (T b ,T m ]A smooth transition from 0 acceleration to the set centrifugal speed.
Alternatively, the acceleration operation of the centrifuge can be performed by controlling the rotational speed of the centrifuge through other existing algorithms, programs or models.
S220, under the condition that a centrifugation ending signal is detected, acquiring a current centrifugation duration of the centrifugal machine and a first mechanical time constant corresponding to a sample type of a current target sample.
S230, based on the current rotation speed of the centrifugal machine, the first mechanical time constant and the current centrifugal time length, the centrifugal machine is controlled to execute the speed reduction operation by adopting a first exponential rotation speed control algorithm until the rotation speed of the centrifugal machine is zero.
According to the technical scheme of the centrifuge control method, under the condition that the centrifuge end signal is detected, the centrifuge is controlled to perform acceleration operation through the second index rotation speed control algorithm, stable acceleration of the centrifuge is achieved, and further the centrifugal effect is improved.
Fig. 3A is a block diagram of a first centrifuge control device according to an embodiment of the present invention, where the embodiment is applicable to a scenario of centrifuge control for nucleic acid extraction based on a silica bead method, and the device may be implemented in hardware and/or software, and integrated into a processor of an electronic device with an application development function.
As shown in fig. 3A, the centrifuge control device includes:
the centrifuge deceleration parameter obtaining module 301 is configured to obtain, when a centrifugation end signal is detected, a current centrifugation duration of the centrifuge and a first mechanical time constant corresponding to a sample type of a current target sample;
the centrifuge deceleration module 302 is configured to control the centrifuge to perform a deceleration operation using a first exponential rotation speed control algorithm based on a current rotation speed of the centrifuge, a first mechanical time constant, and a current centrifugation duration, until the rotation speed of the centrifuge is zero.
Optionally, as shown in fig. 3B, the apparatus further includes a centrifuge acceleration module 303, where the centrifuge acceleration module 303 is configured to:
under the condition that a centrifugal signal is detected, acquiring a set centrifugal speed and a second mechanical time constant corresponding to the sample type of the current target sample;
and controlling the centrifugal machine to execute acceleration operation by adopting a second index rotating speed control algorithm based on the set centrifugal speed and the second mechanical time constant until the rotating speed of the centrifugal machine reaches the set centrifugal speed.
Optionally, as shown in fig. 3C, the apparatus further includes a centrifugation module 304, where the centrifugation module 304 is configured to:
acquiring a first set centrifugation time length;
the centrifuge is controlled to operate at a set centrifugation speed for a first set centrifugation duration.
Optionally, as shown in fig. 3D, the apparatus further includes a centrifugal countdown module 305, and the centrifugal countdown module 305 is configured to:
acquiring a second set centrifugation duration corresponding to the sample type of the current target sample and the current centrifugation duration of the centrifuge;
determining a countdown according to the second set centrifugal time length and the current centrifugal time length;
showing the countdown.
Optionally, as shown in fig. 3E, the apparatus further includes a centrifugal sample determination module 306, the centrifugal sample determination module 306 being configured to:
and acquiring a sample identifier of the current target sample, and determining the sample type of the current target sample according to the corresponding relation between the pre-created sample identifier and the sample type.
Optionally, as shown in fig. 3F, the apparatus further includes a centrifuge self-checking module 307, and the centrifuge self-checking module 307 is configured to:
controlling the centrifugal machine to perform self-checking to obtain a self-checking result;
and displaying prompt information corresponding to the self-checking result.
According to the technical scheme of the centrifuge control method provided by the embodiment of the invention, the rotating speed of the centrifuge in the deceleration stage is controlled based on the index, so that the stable deceleration of the centrifuge is realized, and the centrifugal effect is improved.
The centrifuge control device provided by the embodiment of the invention can execute the centrifuge control method provided by any embodiment of the invention, and has the corresponding functional modules and beneficial effects of the execution method.
Fig. 4 is a block diagram of an electronic device according to an embodiment of the present invention. Electronic devices are intended to represent various forms of digital computers, such as laptops, desktops, workstations, personal digital assistants, servers, blade servers, mainframes, and other appropriate computers. Electronic equipment may also represent various forms of mobile devices, such as personal digital processing, cellular telephones, smartphones, wearable devices (e.g., helmets, glasses, watches, etc.), and other similar computing devices. The components shown herein, their connections and relationships, and their functions, are meant to be exemplary only, and are not meant to limit implementations of the inventions described and/or claimed herein.
As shown in fig. 4, the electronic device 10 includes at least one processor 11, and a memory, such as a Read Only Memory (ROM) 12, a Random Access Memory (RAM) 13, etc., communicatively connected to the at least one processor 11, in which the memory stores a computer program executable by the at least one processor, and the processor 11 may perform various appropriate actions and processes according to the computer program stored in the Read Only Memory (ROM) 12 or the computer program loaded from the storage unit 18 into the Random Access Memory (RAM) 13. In the RAM 13, various programs and data required for the operation of the electronic device 10 may also be stored. The processor 11, the ROM 12 and the RAM 13 are connected to each other via a bus 14. An input/output (I/O) interface 15 is also connected to bus 14.
Various components in the electronic device 10 are connected to the I/O interface 15, including: an input unit 16 such as a keyboard, a mouse, etc.; an output unit 17 such as various types of displays, speakers, and the like; a storage unit 18 such as a magnetic disk, an optical disk, or the like; and a communication unit 19 such as a network card, modem, wireless communication transceiver, etc. The communication unit 19 allows the electronic device 10 to exchange information/data with other devices via a computer network, such as the internet, and/or various telecommunication networks.
The processor 11 may be a variety of general and/or special purpose processing components having processing and computing capabilities. Some examples of processor 11 include, but are not limited to, a Central Processing Unit (CPU), a Graphics Processing Unit (GPU), various specialized Artificial Intelligence (AI) computing chips, various processors running machine learning model algorithms, digital Signal Processors (DSPs), and any suitable processor, controller, microcontroller, etc. The processor 11 performs the various methods and processes described above, such as the centrifuge control method.
In some embodiments, the centrifuge control method may be implemented as a computer program tangibly embodied on a computer-readable storage medium, such as storage unit 18. In some embodiments, part or all of the computer program may be loaded and/or installed onto the electronic device 10 via the ROM 12 and/or the communication unit 19. When the computer program is loaded into RAM 13 and executed by processor 11, one or more steps of the centrifuge control method described above may be performed. Alternatively, in other embodiments, the processor 11 may be configured to perform the centrifuge control method by any other suitable means (e.g., by means of firmware).
Various implementations of the systems and techniques described here above may be implemented in digital electronic circuitry, integrated circuit systems, field Programmable Gate Arrays (FPGAs), application Specific Integrated Circuits (ASICs), application Specific Standard Products (ASSPs), systems On Chip (SOCs), load programmable logic devices (CPLDs), computer hardware, firmware, software, and/or combinations thereof. These various embodiments may include: implemented in one or more computer programs, the one or more computer programs may be executed and/or interpreted on a programmable system including at least one programmable processor, which may be a special purpose or general-purpose programmable processor, that may receive data and instructions from, and transmit data and instructions to, a storage system, at least one input device, and at least one output device.
A computer program for carrying out methods of the present invention may be written in any combination of one or more programming languages. These computer programs may be provided to a processor of a general purpose computer, special purpose computer, or other programmable data processing apparatus, such that the computer programs, when executed by the processor, cause the functions/acts specified in the flowchart and/or block diagram block or blocks to be implemented. The computer program may execute entirely on the machine, partly on the machine, as a stand-alone software package, partly on the machine and partly on a remote machine or entirely on the remote machine or server.
In the context of the present invention, a computer-readable storage medium may be a tangible medium that can contain, or store a computer program for use by or in connection with an instruction execution system, apparatus, or device. The computer readable storage medium may include, but is not limited to, an electronic, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, or device, or any suitable combination of the foregoing. Alternatively, the computer readable storage medium may be a machine readable signal medium. More specific examples of a machine-readable storage medium would include an electrical connection based on one or more wires, a portable computer diskette, a hard disk, a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber, a portable compact disc read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing.
To provide for interaction with a user, the systems and techniques described here can be implemented on an electronic device having: a display device (e.g., a CRT (cathode ray tube) or LCD (liquid crystal display) monitor) for displaying information to a user; and a keyboard and a pointing device (e.g., a mouse or a trackball) through which a user can provide input to the electronic device. Other kinds of devices may also be used to provide for interaction with a user; for example, feedback provided to the user may be any form of sensory feedback (e.g., visual feedback, auditory feedback, or tactile feedback); and input from the user may be received in any form, including acoustic input, speech input, or tactile input.
The systems and techniques described here can be implemented in a computing system that includes a background component (e.g., as a data server), or that includes a middleware component (e.g., an application server), or that includes a front-end component (e.g., a user computer having a graphical user interface or a web browser through which a user can interact with an implementation of the systems and techniques described here), or any combination of such background, middleware, or front-end components. The components of the system can be interconnected by any form or medium of digital data communication (e.g., a communication network). Examples of communication networks include: local Area Networks (LANs), wide Area Networks (WANs), blockchain networks, and the internet.
The computing system may include clients and servers. The client and server are typically remote from each other and typically interact through a communication network. The relationship of client and server arises by virtue of computer programs running on the respective computers and having a client-server relationship to each other. The server can be a cloud server, also called a cloud computing server or a cloud host, and is a host product in a cloud computing service system, so that the defects of high management difficulty and weak service expansibility in the traditional physical hosts and VPS service are overcome.
It should be appreciated that various forms of the flows shown above may be used to reorder, add, or delete steps. For example, the steps described in the present invention may be performed in parallel, sequentially, or in a different order, so long as the desired results of the technical solution of the present invention are achieved, and the present invention is not limited herein.
The above embodiments do not limit the scope of the present invention. It will be apparent to those skilled in the art that various modifications, combinations, sub-combinations and alternatives are possible, depending on design requirements and other factors. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the scope of the present invention.
Claims (10)
1. A centrifuge control method for extracting nucleic acid by a silica bead method, comprising:
under the condition that a centrifugation ending signal is detected, acquiring a current centrifugation duration of the centrifugal machine and a first mechanical time constant corresponding to a sample type of a current target sample;
and based on the current rotation speed of the centrifugal machine, the first mechanical time constant and the current centrifugal time length, controlling the centrifugal machine to execute the speed reduction operation by adopting a first exponential rotation speed control algorithm until the rotation speed of the centrifugal machine is zero.
2. The method according to claim 1, wherein before acquiring the first mechanical time constant corresponding to the current centrifugation duration of the centrifuge and the sample type of the current target sample in the case where the centrifugation end signal is detected, further comprises:
under the condition that a centrifugal signal is detected, acquiring a set centrifugal speed and a second mechanical time constant corresponding to the sample type of the current target sample;
and based on the set centrifugal speed and the second mechanical time constant, adopting a second index rotating speed control algorithm to control the centrifugal machine to execute acceleration operation until the rotating speed of the centrifugal machine reaches the set centrifugal speed.
3. The method according to claim 1, wherein before acquiring the first mechanical time constant corresponding to the current centrifugation duration of the centrifuge and the sample type of the current target sample in the case where the centrifugation end signal is detected, further comprises:
acquiring a first set centrifugation time length;
and controlling the centrifugal machine to operate at the set centrifugal speed for the first set centrifugal time period.
4. The method according to claim 1, wherein, in the case of detecting the centrifugal signal, acquiring the set centrifugal speed and the second mechanical time constant corresponding to the sample type of the current target sample simultaneously includes:
acquiring a second set centrifugation duration corresponding to the sample type of the current target sample and the current centrifugation duration of the centrifuge;
determining a countdown according to the second set centrifugal time length and the current centrifugal time length;
the countdown is shown.
5. The method according to claim 2, wherein, in the case of detecting the centrifugal signal, before acquiring the set centrifugal speed and the second mechanical time constant corresponding to the sample type of the current target sample, further comprises:
and obtaining a sample identifier of the current target sample, and determining the sample type of the current target sample according to the corresponding relation between the pre-created sample identifier and the sample type.
6. The method of claim 1, wherein the first mechanical time constant is the same as the second mechanical time constant.
7. The method of any one of claims 1-4, further comprising, prior to detecting the centrifugal signal:
controlling the centrifugal machine to perform self-checking to obtain a self-checking result;
and displaying prompt information corresponding to the self-checking result.
8. A centrifuge control device, comprising:
the centrifugal machine deceleration parameter acquisition module is used for acquiring the current centrifugal time length of the centrifugal machine and a first mechanical time constant corresponding to the sample type of the current target sample under the condition that a centrifugal end signal is detected;
and the centrifugal machine speed reducing module is used for controlling the centrifugal machine to execute speed reducing operation by adopting a first exponential speed control algorithm based on the current speed of the centrifugal machine, the first mechanical time constant and the current centrifugal time length until the speed of the centrifugal machine is zero.
9. An electronic device, the electronic device comprising:
at least one processor; and
a memory communicatively coupled to the at least one processor; wherein,,
the memory stores a computer program executable by the at least one processor to enable the at least one processor to perform the centrifuge control method of any of claims 1-7.
10. A computer readable storage medium storing computer instructions for causing a processor to execute the centrifuge control method of any one of claims 1-7.
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