CN116699158A

CN116699158A - Molecular diagnostic device

Info

Publication number: CN116699158A
Application number: CN202210894168.6A
Authority: CN
Inventors: 朱元宝; 黄高祥; 赵志翔
Original assignee: Edan Instruments Inc
Current assignee: Edan Instruments Inc
Priority date: 2022-02-25
Filing date: 2022-02-25
Publication date: 2023-09-05
Also published as: CN116699155A

Abstract

The application provides molecular diagnosis equipment, and relates to the technical field of molecular detection. In the molecular diagnosis equipment, a detection card detection seat is used for placing a detection card, the detection card comprises a sample adding cavity and a detection cavity, and the detection card detection seat detects the detection cavity; the pressing disc and the detection card detection seat are clamped with a detection card; the first heating piece is arranged on the detection card detection seat or the pressing disc and is used for heating the detection cavity; the second heating piece is arranged on the detection card detection seat or the pressing disc and is used for heating the sample adding cavity; the control circuit board is respectively and electrically connected with the first heating element and the second heating element, and the first heating element and the second heating element are respectively and independently controlled by the control circuit board to heat. The application utilizes the first and the second heating parts to make the detection card heated to smoothly finish the detection of the detection card when detecting the detection card, and in addition, the detection cavity and the sample adding cavity can be respectively heated by the control of the control circuit board so as to heat according to the requirement of the detection flow in the detection process of the detection card.

Description

Molecular diagnostic device

The application is a divisional application of China patent application with the application number of 202210177162.7 and the name of molecular diagnosis equipment and a detection card conveying seat for the molecular diagnosis equipment, which is applied for 25 days of 2022 and 02.

Technical Field

The application relates to the technical field of molecular detection, in particular to molecular diagnosis equipment.

Background

For molecular diagnostic devices, molecular diagnostic techniques are utilized. The molecular diagnosis technology refers to a diagnosis technology for clinical detection by using nucleic acid or protein as a biomarker, and provides information and decision basis for disease prediction, diagnosis, prevention, treatment and prognosis.

When the molecular diagnostic device detects the detection card, the temperature control needs to be performed on the detection card, and therefore, a specific device is required to perform the temperature control on the detection card.

Disclosure of Invention

One aspect of the present application provides a molecular diagnostic device comprising:

the detection card detection seat is used for placing a detection card, the detection card comprises a sample adding cavity and a detection cavity, and the detection card detection seat is used for detecting the detection cavity;

the pressing plate is used for clamping the detection card with the detection card detection seat;

the first heating piece is arranged on the detection seat or the pressing disc of the detection card and is used for heating the detection cavity;

the second heating piece is arranged on the detection seat of the detection card or the pressing disc and is used for heating the sample adding cavity; and

The control circuit board is respectively and electrically connected with the first heating element and the second heating element, and the first heating element and the second heating element are respectively configured to be independently controlled by the control circuit board to heat.

In another aspect, the present application also provides a molecular diagnostic device comprising:

the pressure resisting disc is provided with a first heating piece and a second heating piece so as to heat the detection card, and the detection card comprises a sample adding cavity and a detection cavity;

the detection card detection seat is provided with a third heating piece and a fourth heating piece so as to heat the detection card, and the detection card detection seat is used for detecting the detection cavity;

the first circuit board is arranged in the pressing disc and is electrically connected with the first heating piece and the second heating piece respectively so as to heat the detection card;

the second circuit board is arranged in the detection seat of the detection card and is respectively and electrically connected with the third heating element and the fourth heating element so as to heat the detection card; and

the control circuit board is respectively and electrically connected with the first circuit board and the second circuit board, and the first circuit board and the second circuit board are used for responding to the control of the control circuit board to drive the first heating piece and the third heating piece to heat the detection cavity and/or drive the second heating piece and the fourth heating piece to heat the sample adding cavity.

the pressure disk for with detect card detects the seat and presss from both sides and establish detect the card includes:

the pressing disc main body is used for clamping the detection card with the detection card detection seat, and an electromagnetic piece is arranged on one side of the pressing disc main body, which is used for generating magnetic acting force when being electrified; and

the pressing piece is positioned at one side of the pressing disc main body, which is clamped with the detection card, and is configured to be connected with the electromagnetic piece by magnetic acting force and is used for being matched with the detection card to carry out centrifugal treatment;

the first heating piece is arranged on the detection seat of the detection card or the pressing disc main body and is used for heating the detection cavity;

the second heating piece is arranged on the detection seat of the detection card or the pressing disc main body and is used for heating the sample adding cavity; and

the control circuit board is respectively and electrically connected with the first heating element, the second heating element and the electromagnetic element, the first heating element and the second heating element are respectively configured to be independently controlled by the control circuit board to heat, and the control circuit board is used for controlling the electrifying of the electromagnetic element.

The application utilizes the detection card detection seat to detect the detection card, and simultaneously utilizes the first heating piece and the second heating piece to assist, so that the detection card is heated to smoothly finish the detection of the detection card.

Drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings that are required to be used in the embodiments will be briefly described below. It is evident that the drawings in the following description are only some embodiments of the present application and that other drawings may be obtained from these drawings without inventive effort for a person of ordinary skill in the art.

FIG. 1 is a schematic perspective view of a molecular diagnostic device according to an embodiment of the present application;

FIG. 2 is an exploded view of the molecular diagnostic device of FIG. 1;

FIG. 3 is a schematic perspective view of the frame of FIG. 1;

FIG. 4 is an exploded view of the drive assembly of FIG. 3;

FIG. 5 is a diagram showing the connection between the frame body and the screw assembly of FIG. 3;

FIGS. 6 and 7 are perspective views of the circuit mounting board of FIG. 3 from different perspectives, respectively;

FIG. 8 is a schematic view of a portion of the frame of FIG. 3;

FIG. 9 is a schematic diagram of the second limit switch in FIG. 8;

FIG. 10 is an exploded view of the pressure plate of FIG. 2 in accordance with the present application;

fig. 11 and 12 are schematic views of the first housing in fig. 10 from different angles;

FIG. 13 is a schematic view of the compression member of FIG. 10 according to the present application;

FIGS. 14 and 15 are schematic views of the first heating element of FIG. 10 from different angles;

FIG. 16 is a schematic diagram of the first circuit board in FIG. 10;

FIG. 17 is a schematic view of the latch of FIG. 10;

FIG. 18 is a cross-sectional view of the retaining member of FIG. 17 taken along line XVII-XVII;

fig. 19 and 20 are schematic views of the second housing in fig. 10 from different angles;

FIG. 21 is a schematic perspective view of the pressure plate of FIG. 10;

FIG. 22 is a schematic view of the first rail of FIG. 21;

fig. 23 is a schematic diagram of a connection structure between the frame 10 and the pressing plate;

FIG. 24 is a schematic view of the shipping assembly of FIG. 2;

FIG. 25 is a schematic view of the carriage of FIG. 24;

FIG. 26 is a schematic view of the shipping member of FIG. 24;

fig. 27 and 28 are schematic views of the sliding seat of fig. 26 from different angles;

FIG. 29 is a schematic view of the third driving member 64 and the card holder of FIG. 26;

FIG. 30 is a schematic view of the connection between the third driving member 64 and the clamping bracket and pressing member in FIG. 2;

FIGS. 31 and 32 are schematic views of the connection structure of the pressure plate and the shipping assembly of FIG. 2, respectively, from different perspectives in accordance with the present application;

FIG. 33 is an exploded view of the test card holder of FIG. 2;

FIG. 34 is an exploded view of the support base of FIG. 33;

fig. 35 and 36 are schematic views of the support base body of fig. 34 from different angles;

FIG. 37 is a schematic view of the photodetector of FIG. 34;

FIG. 38 is a cross-sectional view of the test seat of FIG. 37 taken along line XXXVII-XXXVII;

FIG. 39 is a schematic view of the loading chamber assembly of FIG. 34;

FIG. 40 is a cross-sectional view of the loading chamber assembly of FIG. 39 taken along line XXXIX-XXXIX;

FIG. 41 is a schematic view of the light generator of FIG. 33;

FIG. 42 is a cross-sectional view of the first light generator of FIG. 41;

fig. 43 is an exploded view of the light receiving assembly of fig. 33;

FIG. 44 is a schematic view of the light-receiving member of FIG. 33;

FIG. 45 is a schematic view of the neutron optical path assembly of FIG. 43;

FIG. 46 is a cross-sectional view of the neutron optical path assembly of FIG. 45;

FIG. 47 is a schematic view of the first gasket of FIG. 43;

FIG. 48 is a schematic view of the second gasket of FIG. 43;

FIG. 49 is a schematic view of the second clip of FIG. 43;

FIG. 50 is a schematic diagram of a test card according to an embodiment of the application;

FIG. 51 is a cross-sectional view of the test card of FIG. 50 taken along line L-L;

FIG. 52 is a schematic perspective view of the test card of FIG. 50;

FIG. 53 is a schematic diagram of the test card of FIG. 50 in use.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application. It will be apparent that the described embodiments are only some, but not all, embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment may be included in at least one embodiment of the application. The appearances of such phrases in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments.

In an embodiment of the present application, there is provided a molecular diagnostic device including:

In an embodiment, the first heating element is mounted on the detection card detection seat, and the molecular diagnosis apparatus further includes:

and the third heating piece is arranged at the position, opposite to the first heating piece, on the pressing disc and is used for heating the detection cavity.

In one embodiment, the test card test socket includes:

the supporting seat main body is used for supporting the detection card;

the detection seat is arranged on the support seat main body and used for installing the detection cavity, and the first heating piece is arranged on the detection seat;

One end of the excitation optical fiber is arranged on the detection seat and used for emitting excitation light to the detection cavity; and

and one end of the receiving optical fiber is arranged on the detection seat and is used for receiving fluorescence formed by the irradiation of the excitation light to the detection cavity so as to finish the detection of the detection cavity.

In an embodiment, the supporting seat main body is provided with an assembling table at one side supporting the detection card, the assembling table is used for installing the detection cavity, and the detection seat is installed on the assembling table.

In an embodiment, the assembly table is provided with a receiving hole, the support base body is provided with a recess portion at a side far away from the assembly table, the recess portion is communicated with the receiving hole, and the detection base is located in the recess portion.

In one embodiment, the test seat comprises:

the detection seat main body is arranged in the concave part and provided with an extension part arranged in the accommodating hole, and the extension part is provided with a detection groove for accommodating the detection cavity.

In an embodiment, the number of the detecting seats is plural, the number of the assembling tables is plural, the detecting seats are in one-to-one correspondence with the assembling tables, and the circumference of the detecting seats is provided with the detecting seats.

In an embodiment, the second heating element is disposed on the detection card detection seat, and the molecular diagnostic device further includes:

the first circuit board is electrically connected with the first heating element, the second heating element and the control circuit board respectively, and the first circuit board responds to the control of the control circuit board to drive the first heating element to heat the detection cavity and/or drive the second heating element to heat the sample adding cavity.

In an embodiment, the first circuit board is disposed on a side of the support base body away from the test card.

In an embodiment, the test card test socket further comprises:

and the supporting frame is used for supporting the supporting seat main body.

In one embodiment, the pressing plate includes:

an abutment plate body, the third heating element being mounted within the abutment plate body, the third heating element being configured to be extendable from within the abutment plate body to be heated in abutment with the detection chamber; and

the elastic piece is arranged in the pressure-resisting disc main body and is used for applying acting force to the third heating piece to enable the third heating piece to extend out of the pressure-resisting disc main body, and the third heating piece responds to the acting force overcome by the abutting force of the third heating piece and the detection cavity and contracts inwards of the pressure-resisting disc main body.

In one embodiment, the pressure-bearing plate body includes:

the first shell is provided with a clamping hole, and the third heating piece is arranged in the clamping hole so as to slide in the extending direction of the clamping hole; and

and one end of the elastic piece is abutted with the first heating piece, and the other end of the elastic piece is abutted with the second shell.

In an embodiment, the edge of the first housing, which is far away from the second housing, is provided with a protruding edge, so as to be clamped with the third heating element.

In an embodiment, the number of the clamping holes is multiple, the number of the third heating elements is multiple, the clamping holes are in one-to-one correspondence with the third heating elements, and the periphery of the clamping holes is provided with a plurality of circles.

In an embodiment, the second heating element is disposed on a side of the first housing away from the second housing, the molecular diagnostic device further includes a second circuit board disposed on a side of the first housing facing the second housing, the second circuit board is electrically connected to the second heating element, the third heating element and the control circuit board, and the second circuit board is responsive to control of the control circuit board to drive the third heating element to heat the detection chamber and/or drive the second heating element to heat the sample loading chamber.

and the fourth heating piece is arranged at the position, opposite to the second heating piece, on the pressing disc and is used for heating the sample adding cavity.

In one embodiment, the test card test socket includes:

the supporting seat main body is provided with a clamping hole penetrating through the supporting seat main body, and the supporting seat main body is used for installing the detection cavity;

the sample adding cavity mounting seat is arranged in the clamping hole in a penetrating manner so as to slide in the extending direction of the clamping hole, the sample adding cavity mounting seat is used for mounting the sample adding cavity on one side of the supporting seat main body, on which the detection cavity is mounted, and the second heating piece is arranged in the sample adding cavity mounting seat; and

the elastic piece is in butt joint with the loading cavity mount pad, the loading cavity mount pad responds the elastic piece to the loading cavity mount pad applys effort and in the extending direction of card solid hole with supporting seat main part butt, the loading cavity mount pad responds the detection card to the supporting seat main part applys effort overcoming the effort of elastic piece and in the extending direction of card solid hole slides.

In an embodiment, the test card test socket further comprises:

the support plate is arranged on the support seat main body and is positioned on one side, away from the sample adding cavity mounting seat, of the sample adding cavity, one end of the elastic piece is in butt joint with the support plate, and the other end of the elastic piece is in butt joint with the sample adding cavity mounting seat so as to apply acting force to the sample adding cavity mounting seat in the extending direction of the clamping hole.

In an embodiment, the sample loading cavity mount pad is a plurality of, the elastic component is a plurality of, a plurality of sample loading cavity mount pad and a plurality of elastic component one-to-one, a plurality of the elastic component all with the layer board butt, the layer board is installed the supporting seat main part is kept away from the supporting seat main part is installed the one side of detecting the card.

In one embodiment, the loading chamber mount comprises:

the mounting seat body is provided with a sample adding cavity mounting groove on one side of the detection card for accommodating the detection cavity.

In an embodiment, the detection card is provided with a flow channel to communicate the sample adding cavity with the detection cavity, and the mounting seat body is provided with an abutting part at one side edge, and the abutting part is used for abutting with a part of the detection card where the flow channel is arranged for heating.

In one embodiment, the pressing plate includes:

the fourth heating piece is arranged on the pressing disc main body and is used for being in contact with the sample adding cavity for heating;

the electromagnetic piece is arranged on one side of the pressing disc main body, provided with the fourth heating piece, and is used for generating magnetic acting force by electrifying;

the pressing piece is positioned on one side of the pressing disc main body, where the fourth heating piece is arranged, the electromagnetic piece is connected with the magnetic acting force of the pressing piece, and the pressing piece is configured to be separated from the electromagnetic piece to press the detection card so as to match with the card holder to perform centrifugal treatment on the detection card.

In an embodiment, the pressing member is provided with a yielding portion, so that the sample adding cavity is arranged in the yielding portion, and the fourth heating member is configured to be in abutting connection with the sample adding cavity arranged in the yielding portion for heating.

In an embodiment, the first heating element is disposed on the pressing disc main body, the molecular diagnosis device further includes a second circuit board, the second circuit board is disposed on the pressing disc main body, the second circuit board is electrically connected with the first heating element, the fourth heating element, the electromagnetic element and the control circuit board, the second circuit board responds to control of the control circuit board to drive the first heating element to heat the detection cavity and/or drive the fourth heating element to heat the sample feeding cavity, and the second circuit board responds to control of the control circuit board to energize the electromagnetic element.

Next, a molecular diagnostic device using the molecular diagnostic technique is described. The molecular diagnosis technology refers to a diagnosis technology for clinical detection by using nucleic acid or protein as a biomarker, and provides information and decision basis for disease prediction, diagnosis, prevention, treatment and prognosis. Especially in the face of various sudden infectious diseases, the most cost-effective measure is rapid and accurate molecular diagnosis.

Monolithic structure-molecular diagnostic device 100

Referring to fig. 1 and 2, fig. 1 is a schematic perspective view of a molecular diagnostic device 100 according to an embodiment of the application, and fig. 2 is an exploded view of the molecular diagnostic device 100 in fig. 1. The molecular diagnostic apparatus 100 may include a housing 10, a test card delivery socket 20 mounted on the housing 10, a test card detection socket 30 mounted on the housing 10, and a control circuit board 40 mounted on the housing 10. Wherein the test card delivery base 20 is configured to receive a test card. The test card holder 20 is slidable on the frame 10 relative to the frame 10 such that the test card holder 20 can carry a test card and onto the test card holder 30. The detection card detection seat 30 is used for generating excitation light to detect the detection card and form a detection signal. The control circuit board 40 may be used to control the sliding of the test card carrier 20 on the rack 10, and control the test card carrier 30 to detect the test card, and to receive the test signal and process the test signal to form diagnostic data.

It will be appreciated that in some embodiments, molecular diagnostic device 100 may also include a housing. The housing may house the frame 10, the test card carrier 20, the test card carrier 30, the control circuit board 40, etc. to protect the molecular diagnostic device 100. The shell can also reduce interference of external factors to the detection process of the detection card. In some embodiments, the housing may be provided with a door to allow the test card holder 20 to slide out of the door when the door is open, thereby facilitating placement of the test card on the test card holder 20 and removal of the test card from the test card holder 20. When the isolation door is closed, the protection effect of the shell and the effect of reducing the interference of external factors can be realized.

In addition, in other embodiments, the isolation door may be automatically opened or closed under the control of the control circuit board 40. For example, the isolating door is pushed by a hinge, a hydraulic cylinder, a screw, a gear and other structures under the drive of a driving structure such as a motor.

In addition, in some embodiments, the molecular diagnostic device 100 may further include an output device such as a display, a printer, etc. that may be electrically connected to the control circuit board 40 to output diagnostic data of the molecular diagnostic device 100 through the output device. Of course, a memory storing diagnostic data may also be provided within the molecular diagnostic device 100.

Furthermore, in some embodiments, the molecular diagnostic device 100 may further include an input device such as a display, a keyboard, and a code scanning device 14 (shown in fig. 3) that may be electrically connected to the control circuit board 40, so as to input a control instruction to the molecular diagnostic device 100, for example, the control circuit board 40 through the input device, so as to implement control of the detection card conveying seat 20 and/or the detection card detecting seat 30 by the molecular diagnostic device 100 through the control circuit board 40.

Frame 10

Referring to fig. 3, fig. 3 is a schematic perspective view of the frame 10 in fig. 1. The frame 10 may include a frame body 11 and a first driving device 12 mounted on the frame body 11. The rack body 11 is used for installing the detection card conveying seat 20, the detection card detecting seat 30, the control circuit board 40 and other structures. The first driving device 12 is electrically connected to the control circuit board 40, so as to receive control of the control circuit board 40. The first driving device 12 is used for being connected with the detection card conveying seat 20 so as to drive the detection card conveying seat 20 to slide relative to the frame main body 11 under the control of the control circuit board 40, so that the detection card is carried.

It should be noted that the terms "first," "second," and the like herein are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more of the described features.

The frame body 11 may be entirely in a frame structure. The frame body 11 may be used to mount the test card holder 20 and the test card holder 30, and the test card holder 20 is located above the test card holder 30. Of course, in some embodiments, the mounting positions of the detection card conveying seat 20 and the detection card detecting seat 30 in the rack main body 11 may be other, which is not described herein.

The frame body 11 may include a top plate 111, legs 112 mounted on the top plate 111 and connected to the bottom of the top plate 111, and reinforcing plates 113 provided at the middle and/or bottom of the legs 112. Wherein the legs 112 are used to support the top plate 111. The reinforcing plate 113 serves to reinforce the stability of the lower portion of the leg 112. In some embodiments, the molecular diagnostic apparatus 100 may fix the cabinet to the outer surface of the rack main body 11 in case that the cabinet is provided, to enhance the external appearance of the molecular diagnostic apparatus 100. In some embodiments, the chassis body 11 may be part of a chassis.

In this context, the orientations of "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "upper", "lower" may be used. It is to be understood that the terms "center," "longitudinal," "transverse," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like, herein are directional or positional relationships as indicated based on the drawings, merely to facilitate describing the application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore are not to be construed as limiting the application.

The top plate 111 may be made of a rigid material such as plastic, metal, etc. The top plate 111 may have a plate-like structure, but may have other shapes, which will not be described in detail. A strip hole 1111 may be formed in the middle of the top plate 111 to allow for the detection card holder 20 to be unseated.

The strip-shaped hole 1111 may be matched with the test card holder 20 so that the test card holder 20 extends into the strip-shaped hole 1111, and the test card holder 20 may also slide in the strip-shaped hole 1111. In some embodiments, the extension direction of the bar-shaped aperture 1111 coincides with the sliding direction of the test card holder 20 relative to the rack 10, e.g., the rack body 11. In some embodiments, the strip holes 1111 may be omitted in cases where the top plate 111 is not required to provide strip holes 1111 to yield the test card carrier 20. Of course, in some embodiments, the top plate 111 may be provided with a bar-shaped hole 1111, or may be provided with other shaped holes or grooves like the bar-shaped hole 1111, in order to perform some functions such as saving material, reducing weight, etc.

The top plate 111 may be provided with mounting holes 1112 for mounting the first drive 12. In some embodiments, the mounting holes 1112 may be located in the direction of extension of the bar-shaped holes 1111 to reasonably plan the mounting space on the rack 10, e.g., the rack body 11, to reduce the volume of the molecular diagnostic device 100, making the molecular diagnostic device 100 overall compact. In some embodiments, the mounting holes 1112 may communicate with the bar-shaped holes 1111. In some embodiments, mounting holes 1112 may be omitted.

The top plate 111 may be provided with a connection portion 1113 so that the top plate 111 is connected and fixed with the leg 112 through the connection portion 1113, and the top plate 111 is mounted with the first driving device 12 through the connection portion 1113. In some embodiments, the connection portion 1113 may be a through hole penetrating the top plate 111, and the connection fixing of the top plate 111 and the leg 112 and/or the first driving device 12 may be achieved by matching a connection structure such as a bolt, a screw, a bolt, a socket structure, a buckle structure, and the like with the connection portion 1113, for example, the through hole. In an embodiment, the connection portion 1113, such as a through hole, may be disposed at two opposite sides of the positions of the bar-shaped hole 1111 and the mounting hole 1112, so that the top plate 111 mounts the first driving device 12 through the connection portion 1113. In some embodiments, the connection 1113 may also be other structures such as a socket structure, a bearing, a screw structure, etc. In one embodiment, the connection 1113 may also be omitted.

The legs 112 may be made of a rigid material such as plastic, metal, etc. The supporting leg 112 may have a strip-shaped structure, but may have other shapes, which will not be described in detail. The legs 112 may be provided at one side of the top plate 111, for example, at the bottom of the top plate 111, to support the top plate 111. The support leg 112 can be used for installing the detection card conveying seat 20, so that the detection card conveying seat 20 and the support leg 112 slide relatively, and the purpose of conveying the detection card from the detection card conveying seat 20 to the detection card detecting seat 30 is achieved.

The number of legs 112 may be 1 or more. In some embodiments, the number of legs 112 may also be one of 2, 3, 4, 5, 6, … ….

In an embodiment, the number of legs 112 may be 4, first, second, third and fourth legs 1121, 1122, 1123, 1124, respectively.

It will be appreciated that the designations "first leg", "second leg", "third leg", "fourth leg", and "leg" may be interchangeable in some embodiments. For example, in one embodiment, the "first leg" in other embodiments is referred to as the "second leg", and correspondingly, the "second leg" in other embodiments is referred to as the "first leg".

In an embodiment, the portions of the first, second, third and fourth legs 1121, 1122, 1123, 1124 respectively, that are fixedly connected to the top plate 111 may be sequentially connected to form a quadrilateral, such as a rectangle. In one embodiment, the first leg 1121 and the second leg 1122 are located on the same side of the bar-shaped aperture 1111. The third leg 1123 and the fourth leg 1124 are located on the same side of the bar-shaped aperture 1111. In one embodiment, the parts of the first leg 1121 and the fourth leg 1124 respectively connected and fixed to the top plate 111 are respectively located at two sides in a direction perpendicular to the extending direction of the strip-shaped hole 1111. The portions of the second leg 1122 and the third leg 1123, which are connected and fixed to the top plate 111, are located on both sides in the direction perpendicular to the extending direction of the strip-shaped hole 1111. In one embodiment, the second leg 1122 and the third leg 1123 are disposed on a side of the mounting hole 1112 remote from the bar-shaped hole 1111.

Each leg 112, for example, the first leg 1121, may include a leg body 1125 and a first rail 1126 disposed on the leg body 1125. The top of the leg body 1125 may be engaged with the connection portion 1113, for example, a through hole, through a screw structure such as a bolt, a screw, a plug structure, or a fastening structure, so as to achieve connection and fixation between the top plate 111 and the leg 112. Of course, the top of the leg body 1125 may be connected and fixed to the top plate 111 by welding, bonding, or the like.

The first rail 1126 may be used to mount the test card carrier 20 such that the test card carrier 20 slides on the first rail 1126 and slides in the direction of extension of the first rail 1126.

In one embodiment, the extending direction of the first guide rail 1126 is perpendicular to the extending direction of the bar-shaped hole 1111. In an embodiment, the extending direction of the first rail 1126 may be a vertical direction. It will be appreciated that where a special structure is provided, the direction of extension of the first rail 1126 may be at an angle to the vertical and the angle may be acute.

In an embodiment, the first rail 1126 of the first leg 1121 may be disposed on a side of the leg body 1125 of the first leg 1121 facing the fourth leg 1124. The first rail 1126 of the second leg 1122 is provided at a side of the leg body 1125 of the second leg 1122 facing the third leg 1123. The first rail 1126 of the third leg 1123 is provided at a side of the leg body 1125 of the third leg 1123 facing the second leg 1122. The first rail 1126 of the fourth leg 1124 is provided at a side of the leg main body 1125 of the fourth leg 1124 facing the first leg 1121.

It will be appreciated that in some embodiments, in one leg 112, the leg body 1125 and the first rail 1126 may be of unitary construction. In some embodiments, the first rail 1126 may not be provided in at least a portion of the leg 112. In some embodiments, the first rail 1126 may also be provided at other locations in the frame body 11, such as on the top plate 111.

The reinforcing plate 113 may be made of a hard material such as plastic, metal, etc. The reinforcing plate 113 may have one end connected to the lower portion of one leg 112 and the other end connected to the lower portion of the other leg 112 to achieve relative stability between the two legs 112, thereby enhancing stability of the legs 112. The connection manner between the reinforcing plate 113 and one of the supporting legs 112 may be a screw connection, a plug-in structure, a buckle, welding, bonding, etc., which will not be described in detail. It should be understood that, in order to achieve the stability of the support leg 112, the arrangement mode of the reinforcing plate 113 is not limited to the connection with the lower portion of one support leg 112, but may be that one end of the reinforcing plate 113 is connected and fixed with the top portion or the middle portion of the support leg 112.

The number of the reinforcing plates 113 may be 1 or more. In some embodiments, the number of reinforcing plates 113 may also be one of 2, 3, 4, 5, 6, … …. In some embodiments, the reinforcing plate 113 may also be omitted.

In an embodiment, the number of the reinforcing plates 113 may be 4, namely, the first reinforcing plate 1131, the second reinforcing plate 1132, the third reinforcing plate 1133 and the fourth reinforcing plate 1134.

It will be appreciated that the designations "first stiffener", "second stiffener", "third stiffener", "fourth stiffener" and "stiffener" may be interchangeable in some embodiments. For example, in one embodiment, the "first reinforcing plate" in other embodiments is referred to as the "second reinforcing plate", and correspondingly, the "second reinforcing plate" in other embodiments is referred to as the "first reinforcing plate".

Wherein, one end of the first reinforcing plate 1131 is fixedly connected to the lower portion of the first leg 1121, such as the leg body 1125, and the other end is fixedly connected to the lower portion of the second leg 1122, such as the leg body 1125. The second reinforcing plate 1132 has one end connected to and fixed to the lower portion of the second leg 1122 such as the leg main body 1125 and the other end connected to and fixed to the lower portion of the third leg 1123 such as the leg main body 1125. The third reinforcing plate 1133 is connected and fixed at one end to a lower portion of the third leg 1123, e.g., the leg body 1125, and at the other end to a lower portion of the fourth leg 1124, e.g., the leg body 1125. The fourth reinforcing plate 1134 is connected and fixed at one end to the lower portion of the first leg 1121, e.g., the leg body 1125, and at the other end to the lower portion of the fourth leg 1124, e.g., the leg body 1125.

In an embodiment, the reinforcing plate 113, for example, the first reinforcing plate 1131 and the third reinforcing plate 1133 may be engaged with the first driving device 12.

In an embodiment, a stiffener 113, such as a second stiffener 1132, may be mated with the control circuit board 40.

In one embodiment, the joined reinforcement plate 113 and leg 112 may be of unitary construction.

Referring again to fig. 3, the first driving device 12 may include a driving assembly 121 mounted at the frame body 11, for example, at the mounting hole 1112, and a screw assembly 122 mounted on the frame body 11 and connected to the driving assembly 121.

The driving assembly 121 may be indirectly connected to the screw assembly 122 through a conveyor belt, or may be directly connected to the screw assembly 122 to transmit through the screw assembly 122. The lead screw assembly 122 is connected to the test card delivery socket 20. The screw rod assembly 122 can push the detection card conveying seat 20 to slide on the frame main body 11, such as the first guide rail 1126, under the drive of the driving assembly 121, so as to realize the effect of the detection card conveying seat 20 for carrying the detection card.

Referring to fig. 3 and 4 together, fig. 4 is an exploded view of the drive assembly 121 of fig. 3. The drive assembly 121 can include a mounting bracket 1211 mounted to the housing body 11, such as at the mounting aperture 1112, a first drive 1212 mounted to the mounting bracket 1211, and a synchronization assembly 1213 mounted to the mounting bracket 1211. Wherein the first driving element 1212 is electrically connected to the control circuit board 40 for movement under the control of the control circuit board 40.

The synchronizing assembly 1213 is coupled to the first driver 1212 for driving the first driver 1212. The synchronization assembly 1213 may be indirectly connected to the screw assembly 122 through a conveyor belt, or may be directly connected to the screw assembly 122 to be driven by driving the screw assembly 122.

The mounting bracket 1211 can include a mounting plate 1214 for mounting the first driver 1212 on one side and a crimping plate 1215 that snaps onto the mounting plate 1214 on the other side of the mounting plate 1214. Wherein a synchronization assembly 1213 is mounted between the mounting plate 1214 and the crimping plate 1215.

The mounting plate 1214 may be made of a rigid material such as plastic, metal, etc. The mounting plate 1214 may have a plate-like structure, but may have other shapes, which will not be described in detail. The mounting plate 1214 may be disposed within the mounting hole 1112. In some embodiments, the mounting plate 1214 may also be disposed outside of the mounting holes 1112. In one embodiment, the mounting plate 1214 may be integrally formed with the top plate 111. In an embodiment, mounting plate 1214 may be omitted, and top plate 111 omits mounting holes 1112 in place of mounting plate 1214.

The crimping plate 1215 may include a crimping plate body 1215a disposed opposite the mounting plate 1214 and a spacer 1215b disposed between the crimping plate body 1215a and the mounting plate 1214. Wherein the crimping plate body 1215a can be positioned on a side of the mounting plate 1214 remote from the first driver 1212. The spacer 1215b is used to control the gap between the clamp plate body 1215a and the mounting plate 1214.

The crimping plate body 1215a may be made of a rigid material such as plastic, metal, or the like. The pressing plate body 1215a may have a plate-like structure, but may have other shapes, which will not be described in detail. The crimping plate body 1215a may be positioned outside the mounting aperture 1112 and above the top plate 111.

In some embodiments, when the mounting plate 1214 is positioned outside the mounting holes 1112, such as above or below the top plate 111. The crimping plate body 1215a can be positioned within the mounting aperture 1112. In one embodiment, the mounting plate 1214 may be integrally formed with the top plate 111. In an embodiment, the clamp plate body 1215a may be omitted, and the top plate 111 omits the mounting holes 1112 in place of the clamp plate body 1215a.

The spacers 1215b are connected and fixed to the crimping plate body 1215a and the mounting plate 1214, respectively, to form a space in which the synchronization assembly 1213 can be mounted at a gap between the crimping plate body 1215a and the mounting plate 1214.

In an embodiment, the spacer 1215b may be a spacer plate. The spacer 1215b may be connected and fixed to the mounting plate 1214 and the crimping plate body 1215a by a screw, socket, snap, adhesive, welding, or the like.

In an embodiment, the spacer 1215b may also be a bolt, screw, or the like.

In one embodiment, the spacer 1215b may be of unitary construction with the crimping plate body 1215 a. In one embodiment, the spacer 1215b may also be integrally formed with the mounting plate 1214. In one embodiment, the spacer 1215b is integrally formed with the mounting plate 1214 and the crimping plate body 1215 a.

When the mounting bracket 1211 is mounted on the top plate 111, the crimping plate body 1215a is positioned on a side of the top plate 111 remote from the leg 112. The spacer 1215b is fixedly connected to the top plate 111 at the mounting hole 1112 by screwing, inserting, fastening, welding, bonding, or the like. Meanwhile, when the mounting plate 1214 is positioned in the mounting hole 1112, the spacer 1215b extends into the mounting hole 1112 and is connected and fixed with the mounting plate 1214 in a threaded connection, plug connection, buckle connection, welding, bonding and other manners, so that the first driving piece 1212 is positioned at the bottom of the top plate 111, and reasonable spatial arrangement of the molecular diagnostic device 100 is realized. When the mounting plate 1214 and the buckling plate 1215 are positioned on top of the top plate 111, the spacer 1215b is fixedly connected to the mounting plate 1214 by screwing, plugging, buckling, welding, bonding, or the like. The mounting plate 1214 and the top plate 111 are fixedly connected by screwing, inserting, buckling, welding, bonding and the like. When the mounting plate 1214 is located at the bottom of the top plate 111 and the buckling plate 1215 is located at the top of the top plate 111, the spacer 1215b may be screwed, inserted, snapped, welded, glued, etc. to the mounting plate 1214 through the mounting hole 1112.

The first driver 1212 is mounted to the mounting plate 1214 on a side thereof remote from the clamp plate body 1215 a. The first driving element 1212 and the mounting plate 1214 may be specifically connected and fixed by screwing, plugging, buckling, welding, bonding, etc. In some embodiments, the first driver 1212 may also be mounted to the mounting plate 1214 on a side thereof adjacent to the crimping plate body 1215 a.

The first driver 1212 may be a motor. The output shaft of the motor may extend through the mounting plate 1214 and between the mounting plate 1214 and the crimping plate body 1215 a. In an embodiment, the output shaft of the motor may also penetrate the buckling plate body 1215a, and may be rotatably connected to the buckling plate body 1215a without penetrating the buckling plate body 1215 a. In an embodiment, the first driving element 1212 may be another power source capable of driving the synchronization component 1213 to move, which will not be described in detail.

The synchronizing assembly 1213 can include a first gear 1216 mounted on the output shaft of the first driver 1212 and first and second drive gear sets 1217, 1218, respectively, that are in meshing engagement with the first gear 1216.

Wherein the first gear 1216 rotates when the first driver 1212 is turned on. The first and second gear sets 1217, 1218 may be rotatably coupled to the mounting frame 1211, respectively. The first and second gear sets 1217, 1218 may rotate synchronously as the first gear 1216 rotates, with one rotating clockwise and the other rotating counterclockwise.

The rotational axis of the first drive gear set 1217 is disposed parallel to the output shaft of the first drive member 1212, such as a motor. The rotation shafts of the first gear train 1217 are rotatably connected to the mounting plate 1214 and the clasp plate body 1215a, respectively.

The first drive gear set 1217 may include a second gear 1217a and a first gear 1217b coaxially disposed. Wherein the second gear 1217a may be engaged with the first gear 1216. The first rotation wheel 1217b may be connected to the screw assembly 122 through a conveyor belt, or may be directly connected to the screw assembly 122 to be driven through the screw assembly 122.

The rotational axis of the second drive gear set 1218 is disposed parallel to the output shaft of the first drive member 1212, such as a motor. The rotation shaft of the second gear train 1218 is rotatably coupled to the mounting plate 1214 and the clasp plate body 1215a, respectively.

The second drive gear set 1218 may include a third gear 1218a and a second runner 1218b coaxially disposed. Wherein the third gear 1218a may be meshed with the first gear 1216. The second wheel 1218b may be coupled to the screw assembly 122 by a conveyor belt or may be coupled directly to the screw assembly 122 for transmission through the screw assembly 122.

It will be appreciated that the designations "first gear", "second gear", "third gear", and "gear" may be interchangeable in some embodiments. For example, in one embodiment, the "first gear" in other embodiments is referred to as the "second gear", and correspondingly, the "second gear" in other embodiments is referred to as the "first gear".

It is to be appreciated that the synchronization component 1213 is not limited to the embodiments mentioned above, but may be other types of synchronization components. In addition, when the synchronization assembly 1213 includes gears and a transmission gear set, other structures may be further included, and the number of gears, and the structure and number of transmission gear sets may be set according to practical situations.

Referring to fig. 5, fig. 5 is a connection relationship diagram of the frame body 11 and the screw assembly 122 in fig. 3. The lead screw assembly 122 may include two lead screws, such as a first lead screw 1221 and a second lead screw 1222. In some embodiments, the number of lead screws may also be one of 1, 3, 4, 5, 6, … ….

In some embodiments, the number of lead screws may be at least 2 in order to achieve stable movement of the test card carrier 20.

Two lead screws, for example, a first lead screw 1221 and a second lead screw 1222 are provided on both sides in a direction perpendicular to the extending direction of the strip-shaped hole 1111, respectively. The first lead screw 1221 may be connected to a first gear set 1217, such as a first pulley 1217b, via a belt or directly, and rotation of the first lead screw 1221 may be achieved by rotation of the first gear set 1217, such as the first pulley 1217 b. The second lead screw 1222 may be coupled to a second drive gear set 1218, such as a second runner 1218b, via a conveyor belt or directly, and rotation of the second lead screw 1222 may be accomplished by rotation of the second drive gear set 1218, such as the second runner 1218 b.

Each lead screw, such as the second lead screw 1222, may include a bearing member 1223 mounted at the frame body 11, such as the connection portion 1113, a lead screw body 1224 rotatably coupled to the bearing member 1223 and rotatably coupled to the frame body 11, such as the reinforcing plate 113, and a third rotating wheel 1225 mounted at an end of the lead screw body 1224.

The bearing member 1223 is sleeved outside the screw main body 1224, so as to be rotationally connected with the screw main body 1224. The lead screw body 1224 may be a rod-like structure with external threads provided on a surface. The direction of extension of the lead screw body 1224 may coincide with the direction of extension of the first rail 1126, although in some embodiments the direction of extension of the lead screw body 1224 may also be non-coincident with the direction of extension of the first rail 1126. The lead screw body 1224 may be threadably coupled to the test card delivery socket 20. The third wheel 1225 is located on the same side of the frame body 11 as the second wheel 1218b, e.g., the top plate 111, such as the third wheel 1225 is located on top of the top plate 111 as the second wheel 1218 b.

In one embodiment, the axis of rotation of the third wheel 1225 is parallel to the axis of rotation of the second wheel 1218 b. In an embodiment, the bearing member 1223 may be omitted, and the screw body 1224 may be disposed in the connecting portion 1113, such as a through hole, and directly connected to the top plate 111 in a rotating manner.

It will be appreciated that the designations "first wheel", "second wheel", "third wheel" and "wheel" may be interchangeable in some embodiments. For example, in one embodiment, the "first wheel" in other embodiments is referred to as the "second wheel", and correspondingly, the "second wheel" in other embodiments is referred to as the "first wheel".

In one embodiment, in the first lead screw 1221, the lead screw body 1224 is rotatably coupled to a stiffening plate 113, such as the first stiffening plate 1131. In the second screw 1222, the screw body 1224 is rotatably connected to the reinforcing plate 113, for example, the third reinforcing plate 1133. The third wheel 1225 of the first lead screw 1221 may be connected with the first wheel 1217b of the first gear set 1217 by a conveyor belt. The third wheel 1225 of the second lead screw 1222 may be coupled to the second wheel 1218b of the second drive gear set 1218 by a conveyor belt.

It will be appreciated that the screw assembly 122 and the first guide 1126 are provided to enable sliding movement of the test card carrier 20 on the frame 10 to effect shipping of the test card. Therefore, in the case where the number of the lead screws in the lead screw assembly 122 is sufficient to allow the detection card holder 20 to stably and normally slide on the frame 10, the first guide rail 1126 may not be provided on the molecular diagnostic device 100.

Referring again to fig. 3, a circuit mounting board 13 is provided on the outside of a chassis 10 such as a chassis main body 11 for mounting a control circuit board 40. The circuit mounting board 13 is provided on the same side of the top plate 111 as the leg 112. The circuit mounting board 13 is disposed on the same side of the second leg 1122 and the third leg 1123.

Referring to fig. 3, 6 and 7, fig. 6 and 7 are perspective views of the circuit mounting board 13 of fig. 3 from different angles. The circuit mounting board 13 may be made of a rigid material such as plastic, metal, or the like. The circuit mounting board 13 may include a mounting board body 131. The mounting plate body 131 has a plate-like structure as a whole and may be located on the same side as the second leg 1122 and the third leg 1123. In some embodiments, the mounting plate body 131 may also be directly secured to the second and third legs 1122, 1123. The side of the mounting plate body 131 remote from the leg 112 is used for mounting the control circuit board 40. The mounting plate body 131 may be provided with a through hole 1311 so that the circuit traces pass through the through hole 1311 from within the housing body 11 to electrically connect with the control circuit board 40. In an embodiment, the mounting plate body 131 may also be fixedly connected to the reinforcing plate 113, such as the second reinforcing plate 1132. The side of the mounting plate body 131 away from the support leg 112 is provided with a connection post 1312 for mounting the control circuit board 40, avoiding direct contact of the control circuit board 40 with the mounting plate body 131. The connection post 1312 may be screwed, plugged, welded, etc. to mount the control circuit board 40. The mounting plate main body 131 can isolate the control circuit board 40 from the rack main body 11, so as to avoid the interference of the control circuit board 40 caused by factors such as temperature inside the rack main body 11. Of course, in some embodiments, the mounting plate body 131 may be omitted and the connection posts 1312 may be provided directly on the rack 10, such as the rack body 11, without the need for isolating the control circuit board 40. In one embodiment, the mounting plate body 131 may be integrally formed with the housing body 11.

The mounting plate main body 131 may be provided with a first coaming 132 near the edge of the leg 112, for example, the third leg 1123, and the first coaming 132 may be bent from the edge of the mounting plate main body 131 to the side of the third leg 1123, so as to cover the gap between the mounting plate main body 131 and the third leg 1123, and play a role in isolating at the third leg 1123. In one embodiment, the first shroud 132 may be secured to the third leg 1123 using a screw, snap, plug, weld, adhesive, or the like connection. In some embodiments, the first shroud 132 may be omitted.

The mounting plate body 131 may be provided with a second shroud 133 near the edge of the top plate 111, and the second shroud 133 may be bent from the edge of the mounting plate body 131 to the third leg 1123 side. The second shroud 133 may be fixedly connected to the top plate 111. In one embodiment, the second shroud 133 may be secured to the top plate 111 using a screw, snap, insert, weld, adhesive, or the like connection. In some embodiments, the second shroud 133 may be provided with an opening 1331 for the purpose of yielding the components mounted on the top plate 111. In some embodiments, the second shroud 133 may be omitted.

The mounting plate main body 131 may be provided with a third enclosing plate 134 near the edge of the leg 112, for example, the second leg 1122, and the third enclosing plate 134 may be bent from the edge of the mounting plate main body 131 to the side of the second leg 1122, so as to block the gap between the mounting plate main body 131 and the second leg 1122, and play a role in isolation at the second leg 1122. In an embodiment, the third enclosure 134 may be fastened to the second leg 1122 by a screw, snap, plug, welding, adhesive, or the like. In some embodiments, the third enclosure 134 may be omitted.

It will be appreciated that the designations "first shroud", "second shroud", "third shroud" and "shroud" may be interchangeable in some embodiments. For example, in one embodiment, the "first coaming" in other embodiments is referred to as the "second coaming", and correspondingly, the "second coaming" in other embodiments is referred to as the "first coaming".

Referring again to fig. 3, a frame 10, such as a frame body 11, is provided with a code scanning device 14 electrically connected to a control circuit board 40. The code scanning device 14 may be used to scan an image of an information identification, such as a two-dimensional code, a bar code, etc., on the test card and transmit the image to the control circuit board 40. The control circuit board 40 recognizes the image and acquires the relevant information of the detection card. The code scanning device 14 may be disposed in a path along which the test card holder 20 slides relative to the frame 10 such that when a test card is placed on the test card holder 20, information on the test card identifies the code scanning device 14 for image scanning.

In one embodiment, the code scanning device 14 may be disposed in the path of the test card transport holder 20 sliding within the strip aperture 1111. For example, the code scanning device 14 may be disposed on the reinforcing plate 113, such as the fourth reinforcing plate 1134. The strip-shaped hole 1111 extends to a side away from the mounting hole 1112, that is, the strip-shaped hole 1111 extends to the fourth reinforcing plate 1134 side. In one embodiment, the bar-shaped hole 1111 extends to a side away from the mounting hole 1112 and may extend above the fourth reinforcing plate 1134.

In one embodiment, the code scanning device 14 is disposed on a reinforcing plate 113, such as a fourth reinforcing plate 1134. The test card holder 20 slides in the extending direction of the bar-shaped hole 1111 and slides over the code scanner 14. At this time, when the detection card is placed on the detection card conveying seat 20, the code scanning device 14 immediately scans the image of the information mark on the detection card.

It will be appreciated that the code scanning device 14 may also be located at other locations of the housing 10, such as within the housing 10. In addition, in some embodiments, when the molecular diagnostic device 100 is provided with a housing, the isolation door in the above embodiments is disposed at the fourth reinforcing plate 1134 of the housing and opposite to the code scanning device 14, so that when the detection card conveying seat 20 slides to the isolation door relative to the rack 10, the detection card is placed on the detection card conveying seat 20, and the code scanning device 14 automatically scans the information identifier on the detection card. In one embodiment, the code scanning device 14 may also be disposed on the housing.

Referring again to fig. 5, a first limit switch 15 electrically connected to the control circuit board 40 is disposed on the frame 10, such as the top plate 111. The first limit switch 15 is located below the top plate 111. The first limit switch 15 is located on the sliding travel of the detection card conveying seat 20 relative to the frame 10, so that the first limit switch 15 is triggered when the detection card conveying seat 20 slides, the first limit switch 15 generates a control signal and transmits the control signal to the control circuit board 40, so that the control circuit board 40 controls the operation of the detection card conveying seat 20 according to the control signal, and the detection card conveying seat 20 stops operating, so that the detection card conveying seat 20 stays at a preset position, and limiting of the detection card conveying seat 20 is realized.

In one embodiment, the first limit switch 15 is used to limit the position of the detecting card conveying seat 20 when sliding along the extending direction of the strip-shaped hole 1111.

In one embodiment, the first limit switch 15 is located at a position of the top plate 111 near the strip-shaped hole 1111. The first limit switch 15 may be specifically located at an end of the bar-shaped hole 1111 away from the mounting hole 1112. Of course, the first limit switch 15 may be disposed at another position of the rack 10, or in a case where the molecular diagnostic device 100 is provided with a housing, the first limit switch 15 may be disposed on the housing.

In some embodiments, the first limit switch 15 may be an optocoupler limit switch, and the optocoupler limit switch may be a slot-shaped optocoupler. The groove is arranged between the limit light emitting part and the limit light receiving part in the groove-shaped optocoupler, when the position of the detection card conveying seat 20 is arranged in the groove, the detection card conveying seat 20 blocks light transmission between the limit light emitting part and the limit light receiving part, the groove-shaped optocoupler further generates a control signal and transmits the control signal to the control circuit board 40, so that the detection card conveying seat 20 stops running under the control of the control circuit board 40, and the detection card conveying seat 20 stays at a preset position.

Referring to fig. 8, fig. 8 is a schematic view of a portion of the frame 10 in fig. 3. The rack 10, for example, the rack body 11, may be provided with a second limit switch 16 electrically connected to the control circuit board 40 to limit the detection card conveying seat 20. The second limit switch 16 may be located on the path of the test card carrier 20 sliding on the first rail 1126 to define the position of the test card carrier 20 as it slides on the first rail 1126.

The second limit switch 16 is triggered when the detection card conveying seat 20 slides on the first guide rail 1126, generates a control signal and transmits the control signal to the control circuit board 40, so that the control circuit board 40 controls the operation of the detection card conveying seat 20 according to the control signal, and stops the operation of the detection card conveying seat 20, so that the detection card conveying seat 20 stays at a preset position, and limiting of the detection card conveying seat 20 is achieved.

Referring to fig. 8 and 9 together, fig. 9 is a schematic structural diagram of the second limit switch 16 in fig. 8. The second limit switch 16 may include a mounting housing 161 mounted on the leg 112, e.g., the third leg 1123, and a first sub-limit switch 162 and a second sub-limit switch 163 provided on the mounting housing 161. The first sub-limit switch 162 and the second sub-limit switch 163 are both located on a stroke of the detection card conveying seat 20 sliding on the first guide rail 1126, so that the detection card conveying seat 20 slides on a stroke between the first sub-limit switch 162 and the second sub-limit switch 163. The first sub-limit switch 162 and the second sub-limit switch 163 are electrically connected to the control circuit board 40.

It will be appreciated that the designations "first limit switch", "second limit switch", "sub limit switch", "first sub limit switch", "second sub limit switch", and "limit switch" may be switched between each other in some embodiments. For example, in one embodiment, the "first limit switch" in other embodiments is referred to as a "second limit switch", and correspondingly, the "second limit switch" in other embodiments is referred to as a "first limit switch".

The mounting case 161 is made of a hard material such as plastic, metal, or the like. The mounting case 161 is entirely in the shape of a case. The mounting housing 161 may be mounted on the frame body 11, e.g., the third leg 1123. The mounting housing 161 may be specifically fastened to the frame body 11, for example, the third leg 1123, by a screw connection, a snap connection, a plug connection, a welding connection, an adhesive connection, or the like.

The mounting housing 161 may be located on a side of the third leg 1123 adjacent to the circuit mounting board 13. Of course, the mounting housing 161 may be mounted at other positions of the frame 10, which will not be described in detail.

The first and second sub limit switches 162 and 163 may be disposed at the same side of the mounting case 161. The first sub-limit switch 162 and the second sub-limit switch 163 may specifically be sides of the mounting housing 161 away from the circuit mounting board 13.

The first sub-limit switch 162 can be triggered to generate a signal and transmit the signal to the control circuit board 40 when the detection card conveying seat 20 slides to the detection card detecting seat 30, so that the control circuit board 40 controls the operation of the detection card conveying seat 20 according to the control signal and stops the operation of the detection card conveying seat 20, so that the detection card conveying seat 20 stays at a preset position, and the position limit when the detection card conveying seat 20 slides to the detection card detecting seat 30 is realized.

The second limit switch 163 can be triggered to generate a signal and transmit the signal to the control circuit board 40 when the detection card conveying seat 20 slides to a side far away from the detection card conveying seat 30 (that is, slides to the top plate 111 side), so that the control circuit board 40 controls the operation of the detection card conveying seat 20 according to the control signal and stops the operation of the detection card conveying seat 20, so that the detection card conveying seat 20 stays at a preset position, the position limit when the detection card conveying seat 20 slides to the top plate 111 side is realized, and the mutual damage caused by the contact between the detection card conveying seat 20 and the top plate 111 is reduced.

In an embodiment, the first sub-limit switch 162 and the second sub-limit switch 163 may be optocoupler limit switches, when the position of the detection card conveying seat 20 is disposed in the groove, the detection card conveying seat 20 blocks the light transmission between the limit light emitting portion and the limit light receiving portion, and the groove-shaped optocoupler further generates a control signal and transmits the control signal to the control circuit board 40, so that the first driving device 12, for example, the driving component 121 stops running under the control of the control circuit board 40, and further the detection card conveying seat 20 stays at a predetermined position.

It is understood that the first sub-limit switch 162 and the second sub-limit switch 163 may also be limit pieces such as a travel switch, a proximity switch, and the like. The first and second sub limit switches 162 and 163 may be sensors having a limit function.

In an embodiment, the mounting housing 161 may be omitted, and the first and second sub-limit switches 162 and 163 may be directly disposed at other positions of the rack 10. Of course, in the case where the housing is provided, the molecular diagnostic apparatus 100 may be provided on the housing as well as the mounting case 161. Even, the mounting case 161 may be omitted, and the first and second sub-limit switches 162 and 163 may be directly provided on the cabinet.

Detection card conveying seat 20

Referring to fig. 2, the test card transport housing 20 may include an abutment plate 50 and a shipping assembly 60 mounted on the frame 10, such as a first rail 1126. Wherein the shipping assembly 60 is used to house a test card. The pressing plate 50 is connected with the first driving device 12, so as to slide on the first guide rail 1126 under the action of the first driving device 12, and further drive the delivery assembly 60 to slide on the first guide rail 1126, and the delivery assembly 60 can deliver the detection card and the detection card onto the detection card detection seat 30.

Pressure plate 50

Referring to fig. 10, fig. 10 is an exploded view of the pressing plate 50 of fig. 2 according to the present application. The pressure plate 50 may include a first housing 51 mounted on the frame 10 such as the screw body 1224, an electromagnetic member 52 provided on a side of the first housing 51 facing the detection holder 30 for the detection card, a pressing member 53 for fixing the detection card on the shipping assembly 60, a heating assembly 54 provided on the first housing 51, a first circuit board 55 mounted on the first housing 51 and electrically connected to the electromagnetic member 52 and the heating assembly 54, respectively, a locking member 56 mounted on the first housing 51 for fixing the pressing member 53, a second housing 57 covered on a side of the first housing 51 facing away from the electromagnetic member 52, and a first rail assembly 58 provided on the first housing 51 and mounted on the frame 10 such as the first rail 1126. Wherein the first housing 51 and the second housing 57 are buckled to form an abutting plate main body. The first circuit board 55 may be electrically connected with the control circuit board 40. The electromagnetic member 52 may generate a magnetic force under the control of the control circuit board 40 to attract the pressing member 53 to the first housing 51. The electromagnetic member 52 can eliminate the magnetic force under the control of the control circuit board 40 to avoid the attraction of the pressing member 53. The heating assembly 54 may heat the test card under the control of the control circuit board 40. The first slide rail assembly 58 is slidable on the frame 10, such as the first rail 1126. The first housing 51 is connected with the frame 10 such as the screw main body 1224 to slide in the extending direction of the first rail 1126 by the rotation of the screw main body 1224.

Referring to fig. 11 and 12, fig. 11 and 12 are schematic views of the first housing 51 in fig. 10 from different angles. The first housing 51 may be made of a hard material such as plastic, metal, etc. The first housing 51 may have a plate-like structure, but may have other shapes, which will not be described in detail. The first housing 51 may include a housing body 511. The housing body 511 is provided with a receiving groove 512 toward the middle of the side of the second housing 57 for receiving the first circuit board 55 and the locking member 56. The cross section of the receiving groove 512 may be circular or may be other shapes.

The case body 511 may be provided with a catching hole 513 around the receiving groove 512 for mounting the heating assembly 54. The locking holes 513 may be circumferentially uniformly distributed around the receiving groove 512. The number of the catching holes 513 may be 1 or more. In some embodiments, the number of the snap holes 513 may also be one of 2, 3, 4, 5, 6, … …. In one embodiment, the number of the clamping holes 513 may be specifically 6. In one embodiment. The shape of the clamping hole 513 is a section of a ring structure.

The housing body 511 is provided with a cutout 514 to allow for the shipping assembly 60. The notch 514 extends inward from one side edge of the case main body 511 near the fourth reinforcing plate 1134. The gap 514 may be disposed opposite the strip-shaped aperture 1111 and the direction of extension of the gap 514 may be consistent with the direction of extension of the strip-shaped aperture 1111 such that the shipping component 60 slides within both the strip-shaped aperture 1111 and the gap 514. In one embodiment, the notch 514 is located between two adjacent clamping holes 513.

The housing body 511 is bent in the accommodating groove 512 toward the side close to the second housing 57 at the edge of the opening 514 to form a sidewall 5111, so as to isolate the opening 514 from the accommodating groove 512. In one embodiment, the surface of the sidewall 5111 adjacent to the second housing 57 is flush with the surface of the housing body 511 adjacent to the second housing 57. In one embodiment, the sidewall 5111 can be used to support the second housing 57.

The housing body 511 is provided with a first insertion hole 5112 and a second insertion hole 5113 penetrating the housing body 511 in the receiving groove 512 so that the locking member 56 is mounted at the insertion holes. In an embodiment, the mating Kong Liru first mating holes 5112 and the second mating holes 5113 may be omitted.

The housing body 511 is provided with a stopper 5114 in the accommodation groove 512 to restrict the mounting position of the first circuit board 55. For example, the limiting posts 5114 are disposed around the notch 514 to form a space for mounting the first circuit board 55 in cooperation with the housing body 511, so as to limit the mounting position of the first circuit board 55. In one embodiment, the limiting post 5114 is provided with a communication hole 5114a, so that the circuit trace penetrates the communication hole 5114a from the side of the housing body 511 close to the electromagnetic member 52 and extends into the accommodating groove 512 to be electrically connected with the first circuit board 55.

In an embodiment, the limiting post 5114 can also be used to abut against the second housing 57 to support the second housing 57. In one embodiment, the stop posts 5114 can also be omitted. In an embodiment, the communication hole 5114a may be directly provided at other positions of the case body 511 instead of the stopper post 5114.

The housing body 511 is provided with a connection post 5115 in the receiving groove 512 for mounting the first circuit board 55 to avoid the first circuit board 55 from directly contacting the housing body 511. In an embodiment, the connection post 5115 may be connected to and fixed to the first circuit board 55 by a screw connection, a socket connection, a clip connection, an adhesive connection, a welding connection, or the like. In an embodiment, the connection post 5115 may be omitted, and the first circuit board 55 is directly fixed in the receiving groove 512.

The edge of the side, far away from the second casing 57, of the clamping hole 513 of the casing body 511 is bent into the clamping hole 513 to form a convex edge 5116, so that the heating component 54 is clamped and mounted, and the heating component 54 is prevented from sliding off the side, close to the electromagnetic piece 52, of the casing body 511. A communication port 5117 is provided between the clamping hole 513 and the accommodating groove 512 so that a circuit trace connected to the heating assembly 54 is electrically connected to the first circuit board 55 through the communication port 5117.

The housing body 511 is provided with a first screw portion 515 near the screw assembly 122, for example, a first screw 1221. The housing body 511 is provided with a second screw portion 516 near the screw assembly 122, for example, the second screw 1222. The screw parts, for example, the first screw part 515 and the second screw part 516 may include a connection lug 5151 extending from the housing body 511 and a screw 5152 mounted on the connection lug 5151. The screw 5152 can be sleeved on the screw assembly 122, such as the screw body 1224. The screw 5152 is internally provided with an internal thread engaged with an external thread of the screw main body 1224 to move the housing main body 511 in an extending direction of the screw assembly 122, for example, the screw main body 1224, upon rotation of the screw assembly 122, for example, the screw main body 1224.

The case body 511 is provided with positioning holes 517 for positioning the position of the detection card.

The middle part of the side surface of the case body 511 away from the second case 57 is provided with a relief groove 518 for accommodating the electromagnetic member 52, the pressing member 53, and the heating element 54. In an embodiment, the cross section of the relief groove 518 is circular, but other shapes are also possible, and will not be described. The relief groove 518 and the accommodating groove 512 are arranged back to back relative to the housing body 511, so that the relief groove 518 is communicated with the notch 514, the first plug hole 5112 and the second plug hole 5113 of the plug Kong Liru are positioned in the relief groove 518, the communication hole 5114a on the limit post 5114 is positioned in the relief groove 518, and the clamping hole 513 is positioned around the relief groove 518. In one embodiment, the relief slots 518 may be omitted.

In one embodiment, the housing body 511 has a plurality of accommodating grooves uniformly distributed on the inner circumference of the relief groove 518 for mounting the electromagnetic member 52. The number of the accommodating grooves may be plural, and the specific number may be one of 2, 3, 4, 5, 6, … …, etc. In one embodiment, the number of the receiving grooves may be 2, for example, the first receiving groove 5118 and the second receiving groove 5119.

Referring to fig. 10 again, the electromagnetic member 52 can be energized to generate a magnetic force, so as to adsorb and fix the pressing member 53. The electromagnet 52 may include a first electromagnet 521 and a second electromagnet 522 electrically connected to the first circuit board 55, respectively. Wherein, the first electromagnet 521 may be installed in the first accommodating groove 5118. The second electromagnet 522 may be installed in the second accommodating groove 5119. Specifically, the first electromagnet 521 and the second electromagnet 522 may be fixed on the housing body 511 by a connection manner such as screwing, clamping, inserting, welding, bonding, and the like. In one embodiment, the circuit traces electrically connected to the first electromagnet 521 and the second electromagnet 522 pass through the communication hole 5114a to be electrically connected to the first circuit board 55. In one embodiment, solenoid 52 may be omitted.

Referring to fig. 13, fig. 13 is a schematic structural view of the pressing member 53 in fig. 10 according to the present application. The number of the pressing members 53 may be 1 or more. In one embodiment, the number of the pressing members 53 may be 2, namely, the first pressing member 531 and the second pressing member 532. A gap 533 is provided between the two pressing members 53. The gap 533 is disposed opposite the strip aperture 1111 to yield the shipping assembly 60 such that the shipping assembly 60 can move in both the gap 533 and the strip aperture 1111.

Each of the pressing members 53 may be made of a hard material such as metal, etc., and specifically may be made of metal such as iron, etc., which is attracted by an electromagnet under a magnetic force. Of course, in some embodiments, each hold-down member 53 may also be made of a rigid material, such as plastic, metal, etc., to engage the locking member 56.

Each pressing member 53 may have a plate-like structure, and may have a circular portion or an annular portion, but may have other shapes, which will not be described. The pressing member 53, for example, the first pressing member 531 may include a pressing member body 5311. The compression body 5311 may be provided with a relief portion 5312 to relief the test card to increase the contact area between the compression body 5311 and the test card, thereby limiting the test card. In one embodiment, the relief 5312 may be a perforation or a notch.

The pressing piece main body 5311 of the first pressing piece 531 is provided with a sub-relief portion 5313 toward the edge of the second pressing piece 532. The pressing piece main body 5311 of the second pressing piece 532 is provided with a sub-relief portion 5313 toward the edge of the first pressing piece 531. The sub-abdication portion 5313 of the first pressing member 531 and the sub-abdication portion 5313 of the second pressing member 532 are disposed opposite to each other, and can form an abdication portion for abdicating the detection card, so as to increase the contact area between the pressing member main body 5311 and the detection card, thereby limiting the detection card. In one embodiment, the child offering portion 5313 may be a notch.

In an embodiment, the abdication portions in the above embodiment may be uniformly distributed circumferentially, so as to reasonably fix and limit the detection card. It is understood that the number of relief portions may be identical to the number of the card-engaging holes 513 or the number of the detection cards.

The compression member body 5311 is provided with a first snap-in portion 5314 for removable connection with the shipping assembly 60.

In an embodiment, the first and second pressing members 531 and 532 may be of a unitary structure, with the gap 533 being provided only at a position opposite to the strip-shaped hole 1111. The gap 533 extends inward from the edge of the pressing piece 53. In one embodiment, the gap 533 may also be omitted and the hold down 53 may be included as part of the shipping assembly 60.

When the electromagnet 52 attracts the pressing member 53, one electromagnet such as the first electromagnet 521 in the electromagnet 52 may attract the surface of the first pressing member 531 such as the pressing member main body 5311, and the other electromagnet such as the second electromagnet 522 may attract the surface of the second pressing member 532 such as the pressing member main body 5311.

In one embodiment, the hold-down member 53 may also be locked with the locking member 56. For example, the clamp body 5311 may be clamped between adjacent two of the relief portions by the locking member 56. Of course, a corresponding connection structure such as a connection post, a lifting lug, or the like may be provided on the pressing member main body 5311 to be clamped and fixed by the locking member 56.

Referring again to fig. 10, the heating assembly 54 may include a first heating element 541 mounted on a side of the first housing 51, e.g., the housing body 511, adjacent to the second housing 57, and a second heating element 542 mounted on a side of the first housing 51, e.g., the housing body 511, remote from the second housing 57. The first heating member 541 cooperates with the second heating member 542 to heat the test card when in abutment with or in a suitable scene or position.

It will be appreciated that the designations "first heating element", "second heating element", and "heating element" may be interchangeable in some embodiments. For example, in one embodiment, the "first heating element" in other embodiments is referred to as the "second heating element", and correspondingly, the "second heating element" in other embodiments is referred to as the "first heating element".

Referring to fig. 14 and 15, fig. 14 and 15 are schematic views of the first heating element 541 of fig. 10 from different angles. The first heating member 541 may include a heating body 5411. The heating body 5411 may be made of a thermally conductive rigid material such as metal to facilitate heating of the test card. Heating element such as heating resistor may be provided in heating body 5411.

The heating body 5411 may be disposed in the first housing 51, for example, the clamping hole 513, and clamped with the first housing 51, for example, the housing body 511, so as to mount the heating body 5411 on the first housing 51.

The surface of the heating body 5411 facing the side of the second housing 57 is provided with a groove 5412 to be engaged with the second housing 57. The edge of the heating body 5411 facing the side of the second housing 57 is provided with a clamping edge 5413, so that the heating body 5411 is placed in the clamping hole 513 from the side of the first housing 51 close to the second housing 57 and is exposed at the side of the first housing 51 far from the second housing 57, and meanwhile, the clamping edge 5413 is matched and clamped with the protruding edge 5116, so that the heating body 5411 is prevented from slipping from the side of the first housing 51 close to the electromagnetic member 52.

In some embodiments, when the heating body 5411 is positioned in the clamping hole 513, the circuit trace electrically connected with the heating device inside the heating body 5411 may be electrically connected with the first circuit board 55 through the communication port 5117 to realize control of the heating device inside the heating body 5411.

It will be appreciated that in one embodiment, the heating body 5411 may be integrally constructed with the first housing 51, such as the housing body 511.

Referring to FIG. 10, the second heating member 542 can have a generally annular configuration. The second heating member 542 may be made of a heat conductive hard material such as metal, and may have a heating device such as a heating resistor disposed therein. The second heating member 542 is mounted in the relief groove 518 of the housing body 511. The second heating element 542 may be fixed on the yielding groove 518 by a connection manner such as a screw connection, a plug connection, a buckle connection, etc. The second heating element 542 is provided with a notch 5421 to yield the gap 514 and the shipping assembly 60.

In some embodiments, when the second heating element 542 is located in the yielding groove 518, the circuit trace electrically connected to the heat generating device inside the second heating element 542 may be electrically connected to the first circuit board 55 through the communication hole 5114a, so as to control the heat generating device inside the second heating element 542.

Referring to fig. 16, fig. 16 is a schematic structural diagram of the first circuit board 55 in fig. 10. The first circuit board 55 may have a ring-shaped structure as a whole. The first circuit board 55 is provided with electronic components such as resistors, capacitors, and inductors. The first circuit board 55 is mounted in the receiving groove 512 of the case body 511. The first circuit board 55 may be limited by the limit posts 5114 to avoid shaking. The first circuit board 55 may be fixed on the connection post 5115 by a screw connection, a plug connection, a buckle connection, or the like. The first circuit board 55 is provided with a notch 551 to yield the side wall 5111, the notch 514, and the shipping assembly 60. The first circuit board 55 may be electrically connected to the heat generating device in the heating assembly 54 and the electromagnetic member 52, respectively, so as to control the heat generating device in the heating assembly 54 and the electromagnetic member 52, respectively. In an embodiment, the first circuit board 55 may be omitted without sharing the working pressure for the control circuit board 40, and the heat generating devices and the electromagnetic members 52 in the heating assembly 54 may be directly electrically connected with the control circuit board 40.

Referring to fig. 17 and 18, fig. 17 is a schematic structural view of the locking member 56 of fig. 10, and fig. 18 is a sectional view of the locking member 56 of fig. 17 taken along the line XVII-XVII. Retaining member 56 may include a retaining housing 561 secured to housing body 511, a linkage assembly 562 disposed within retaining housing 561, and a retaining pawl 563 disposed outside retaining housing 561 and coupled to linkage assembly 562.

Specifically, the locking housing 561 is hollow, and the blocking walls 5611 are provided at opposite sides of the opening, and the blocking walls 5611 are protruded toward the locking housing 561. The lock case 561 is provided with a relief hole 5612 in a portion adjacent to the engagement wall 5611. The lock housing 561 is provided with a latch 5613 in the relief hole 5612. The latch 5613 is elastically deformable. The latch 5613 protrudes outward from the lock housing 561. When the locking member 56 is mounted on the housing body 511, an end of the locking housing 561 remote from the catching wall 5611 protrudes into the first insertion hole 5112 or the second insertion hole 5113 from the first housing 51, for example, the side of the housing body 511 remote from the second housing 57. The clamping block 5613 is elastically deformed by the extrusion of the first housing 51, for example, the housing body 511, so that the clamping block 5613 passes through the plugging hole, and further, the housing body 511 is clamped at the position of the yielding hole 5612, the clamping wall 5611 is located at one side of the housing body 511 away from the second housing 57 and is abutted with the bottom surface of the yielding groove 518, the clamping block 5613 is located at one side of the housing body 511 close to the second housing 57 and is abutted with the bottom surface of the accommodating groove 512, and further, under the action of the clamping wall 5611 and the clamping block 5613, the clamping installation of the locking housing 561 and the first housing 51, for example, the housing body 511 is realized. It is to be understood that the locking housing 561 may also be fixed to the housing body 511 by a screw connection, a plug connection, a buckle connection, an adhesive connection, a welding connection, etc., which will not be described.

The linkage assembly 562 may include a linkage body 5621 mounted inside the locking housing 561, a connector 5622 slidably coupled to the linkage body 5621, an elastic member 5623 mounted on the linkage body 5621 and the connector 5622 and forcing the connector 5622 to slide out of the locking housing 561 with respect to the linkage body 5621, and a linkage member 5624 provided on the linkage body 5621 to lock or unlock the connector 5622.

The interlocking body 5621 is hollow and columnar, is provided in the lock case 561, and extends from the bottom surface in the lock case 561 to the position of the latch 5613. In one embodiment, the linkage body 5621 may be integrally constructed with the lock housing 561. In one embodiment, the linkage body 5621 may be omitted.

The connecting pieces 5622 are disposed in the linkage main body 5621, and may be disposed in a column shape, wherein an outer diameter of one part of the connecting pieces 5622 is larger than an outer diameter of the other part of the connecting pieces 5622, and one end of the connecting piece 5622 having a larger outer diameter is fixedly connected with the locking claw 563. In one embodiment, the outer diameter of the connector 5622 is uniform.

The elastic member 5623 is fitted over the smaller outer diameter portion of the connecting member 5622. In an embodiment, the elastic member 5623 may be a spring, and is sleeved around the connecting member 5622, where one end abuts against the linkage body 5621 or the locking housing 561, and the other end abuts against the connecting member 5622. It is understood that the elastic member 5623 may be made of other elastic materials, which will not be described in detail.

The link 5624 is fixed inside the link body 5621 to lock or unlock the link 5624. The linkage 5624 may be an electromagnet, for example, the electromagnet is electrically connected to the control circuit board 40, so as to be under the control of the control circuit board 40 to adsorb and fix the connection 5622 at a certain position, so that the connection 5622 cannot move, and the connection 5622 is locked, and when the connection 5622 is unlocked, the linkage 5624 is also under the control of the control circuit board 40, so as to unlock the connection 5622 at a certain position. In one embodiment, the linkage 5624 may also be other structures such as an electromagnet. Of course, the linkage 5624 may also be a mechanical structure, such as a wheel, a ratchet, or the like, that can lock or unlock the connector 5622.

In one embodiment, the linkage 5624 may be configured to:

when the link 5624 locks the link 5622, the link 5622 moves again into the lock housing 561 to slide relative to the link body 5621, thereby triggering the link 5624 and breaking the state in which the link 5624 locks the link 5622.

When the link 5624 does not lock the link 5622, the link 5622 moves into the lock housing 561 to slide relatively to the link body 5621, thereby triggering the link 5624 such that the link 5624 locks the link 5622.

When the locking piece 56 is used, when the locking claw 563 is aligned with the position of the pressing piece 53, the locking claw 563 can move to one side of the pressing piece 53 under the driving of the first shell 51, so that the locking claw 563 is abutted with the pressing piece 53, the locking claw 563 receives an abutting force moving inwards of the locking shell 561, and then moves inwards of the locking shell 561, and meanwhile receives the extrusion force of the locking shell 561 to the locking claw 563, so that the locking claw 563 is closed to clamp the pressing piece 53, such as a position between two adjacent abdications or a structure such as a connecting column or a connecting lug, and clamping locking of the pressing piece 53 is achieved. At the same time, the engagement force of the locking pawl 563 against the movement into the locking housing 561 triggers the link assembly 562, and the link assembly 562 maintains the locking state of the locking pawl 563. When the locking claw 563 keeps the locking state, the locking claw 563 receives the abutting force moving into the locking shell 561 again, the locking claw 563 moves into the locking shell 561 again, the linkage assembly 562 is triggered again, the locking state of the locking claw 563 is broken by the linkage assembly 562, unlocking is achieved, the locking claw 563 moves to the side far away from the locking shell 561 under the action of the linkage assembly 562, the locking claw 563 is opened, the pressing piece 53 cannot be clamped and locked, and the pressing piece 53 is put down.

In one embodiment, locking member 56 may also be a door lock switch. In one embodiment, retaining member 56 may also be omitted in the presence of solenoid 52.

Referring to fig. 19 and 20, fig. 19 and 20 are schematic views of the second housing 57 in fig. 10 from different angles. The second housing 57 may include a cover body 571 that may be snapped with the first housing 51, e.g., the housing body 511. The cover body 571 can be connected and fixed with the first housing 51, for example, the housing body 511, by a connection manner such as a screw connection, a plug connection, a buckle connection, a welding connection, an adhesive connection, etc., which will not be described in detail.

The cover body 571 may be made of a rigid material such as plastic, metal, etc. The cover body 571 is provided with a through hole 572. The through hole 572 may be disposed opposite to the receiving groove 512 to yield the first circuit board 55 such that the first circuit board 55 is exposed. In an embodiment, the through hole 572 may be omitted, and the cover body 571 may completely cover the first housing 51, for example, the housing body 511. In an embodiment, the size of the through hole 572 may be adjusted such that the through hole 572 corresponds to a portion of the opening 514 in the housing body 511 to yield the shipping assembly 60, and the cover body 571 covers the first circuit board 55.

The cover body 571 is provided with a notch 573. The notch 573 is provided extending inward from the edge of the cover main body 571 so as to communicate with the through hole 572. The opening 573 is disposed at a position of the cover body 571 opposite to the opening 514, so that when the cover body 571 is buckled with the housing body 511, the opening 573 communicates with the opening 514 to yield the shipping component 60, so that the shipping component 60 can slide in the opening 573.

The cover body 571 is provided with a fixing column 574 on a side facing the first housing 51. The fixing column 574 protrudes from the surface of the cover body 571. The fixing post 574 is located at a position of the cover body 571 opposite to the groove 5412 of the heating component 54, so that a spring is sleeved on the fixing post 574, so that one end of the spring abuts against the cover body 571, and the other end abuts against the portion of the heating component 54 in the groove 5412. It will be appreciated that the heating element 54 is movable relative to the first housing 51 towards the second housing 57 when the side of the first housing 51 remote from the second housing 57 is forced by the spring, which is compressed. In one embodiment, the fixation post 574 may be omitted. In an embodiment, the spring may be replaced by other elastic members, which will not be described in detail.

The cover body 571 is provided with a hanging tab 575 at a side remote from the first housing 51 to be connected with the shipping assembly 60. The hanging lugs 575 are connected and fixed on the cover body 571 in a connecting mode of screw connection, plug connection, buckle connection, welding, bonding and the like. In an embodiment, the number of lugs 575 may be two, such as a first lug 5751 and a second lug 5752. The first and second lugs 5751 and 5752 are symmetrically arranged. It will be appreciated that the number and placement of the tabs 575 may be set as desired as the tabs 575 function to connect the shipping assembly 60.

The cover body 571 is further provided with a positioning hole 576, and the positioning hole 576 is located on the cover body 571 at a position opposite to the positioning hole 517, so that when the cover body 571 is buckled with the housing body 511, the positioning hole 576 is communicated with the positioning hole 517, and positioning of the detection card is achieved.

Referring to fig. 10 and 21, fig. 21 is a schematic perspective view of the pressing plate 50 in fig. 10. The first slide rail assembly 58 is disposed on the first housing 51 to effect a sliding connection of the first housing 51 with the frame 10, such as the first rail 1126. The first slide assembly 58 may include a plurality of slides. The particular number of slide rails may be the same as the number of first slide rails 1126, and in some embodiments, the number of slide rails may be less than the number of first slide rails 1126.

In an embodiment, the number of the sliding rails may be 4, which are the first sliding rail 581, the second sliding rail 582, the third sliding rail 583, and the fourth sliding rail 584, respectively.

Referring to fig. 21 and 22, fig. 22 is a schematic structural view of the first rail 581 of fig. 21. Each of the slide rails such as the first slide rail 581 may include a first slide rail mount 5811 provided on the first housing 51 such as the housing body 511 and a first slide rail member 5812 mounted on the first slide rail mount 5811. Wherein the first rail member 5812 may be mounted on the first rail 1126 to enable relative sliding movement of the first rail member 5812 and the first rail 1126.

The first rail mount 5811 may be made of a rigid material such as plastic, metal, or the like. The first rail mount 5811 may be fixed to a side surface of the first housing 51, for example, the housing body 511, by a screw connection, a plug connection, a snap connection, a welding connection, an adhesive connection, or the like. The first rail mount 5811 is bent toward the cover body 571 on a side away from the detection card detection seat 30 to form a bent portion 5814. The bending portion 5814 may abut against a side of the second case 57 away from the first case 51. In an embodiment, the fastening structure such as a bolt, a screw, or the like may sequentially pass through the bending portion 5814 and the second housing 57 and be connected and fixed with the first housing 51, and of course, other manners such as plugging, buckling, welding, or bonding may be used to achieve the connection and fixation relationship between the bending portion 5814 and the second housing 57 and the first housing 51.

In an embodiment, a limiting plate 5813 may be disposed on a sliding rail, such as the first sliding rail 581, so as to cooperate with the second limiting switch 16, for example, when the pressing plate 50 slides with the frame 10, such as the first sliding rail 1126, the limiting plate 5813 may slide on the stroke of the pressing plate 50, when the limiting plate 5813 slides to a predetermined position, may be disposed in a groove of the second limiting switch 16, such as a groove-shaped optocoupler, to block light transmission between the limiting light emitting portion and the limiting light receiving portion, so that the groove-shaped optocoupler is triggered to generate a control signal and transmit the control signal to the control circuit board 40, and under the control of the control circuit board 40, the operation of the first driving device 12, such as the driving assembly 121, is stopped to stop the movement of the pressing plate 50. It is understood that the limiting plate 5813 may be disposed on other sliding rails of the first sliding rail assembly 58, or may be disposed at other locations of the pressing plate 50.

Referring to fig. 23, fig. 23 is a schematic diagram illustrating a connection structure between the frame 10 and the pressing plate 50. Wherein the pressing plate 50 is mounted on the frame 10. The first rail member 5812 of the first rail 581 is mounted on the first rail 1126 on the third leg 1123. Accordingly, the first rail member 5812 of the second rail 582 is mounted on the first rail 1126 on the fourth leg 1124. The first rail member 5812 of the third rail 583 is mounted on the first rail 1126 on the first leg 1121. The first rail member 5812 of the second rail 582 is mounted on the first rail 1126 on the second leg 1122. The first screw 515 is screw-coupled to a first screw 1221, for example, a screw body 1224. The second screw 516 is screw-coupled to a second screw 1222, such as a screw body 1224. When the driving assembly 121 moves, the first lead screw 1221 and the second lead screw 1222 are driven to move synchronously, and thus, the first lead screw 1221 and the second lead screw 1222 both rotate relatively to the pressing plate 50, so that the first sliding rail assembly 58, such as the first sliding rail member 5812, of the pressing plate 50 can slide on the first sliding rail 1126, thereby realizing the position movement of the pressing plate 50, in particular, the position movement of the pressing plate 50 in the vertical direction.

Shipping assembly 60

Referring to fig. 24, fig. 24 is a schematic view of the shipping assembly 60 of fig. 2. The shipping assembly 60 may include a carriage 61 disposed above the pressure plate 50 and mounted on the frame 10, such as the first rail 1126, and a shipping member 62 mounted on the carriage 61. Wherein the carriage 61 is slidable on the frame 10, e.g. the first rail 1126. The carriage 61 is connected to the pressing plate 50 to slide on the frame 10 together with the pressing plate 50 in some scene scenarios. The shipper 62 may be used to place a test card. The shipper 62 is slidable relative to the carriage 61. The sliding direction of the shipper 62 with respect to the carriage 61 is different from the sliding direction of the carriage 61 with respect to the frame 10.

It will be appreciated that when the shipping assembly 60 is extended, the shipping member 62 slides on the carriage 61 to slide to a first position outside of the rack 10, completing the extension, and placing the test card when the shipping assembly 60 is in the extended condition. The shipping assembly 60 is then slid over the carriage 61 to a second position within the rack 10 to complete the retraction as the shipping assembly 60 is retracted and is slidable between a third position and a fourth position on the first rail 1126 as the shipping assembly 60 is in the retracted state. In some embodiments, the shipping assembly 60 may be extended in the third position. In some embodiments, the shipping assembly 60 may be extendable at a position between the third position and the fourth position.

Referring to fig. 25, fig. 25 is a schematic structural view of the carriage 61 in fig. 24. The carriage 61 may include a mount 611, a second slide rail assembly 612 mounted on the mount 611 and slidably coupled to the frame 10, such as the first rail 1126, a second rail 613 mounted on the mount 611 for mounting the shipper 62, and a second driving device 614 for driving the shipper 62 to slide on the second rail 613.

It will be appreciated that the designations "first drive", "second drive", and "drive", etc., may be interchanged in some embodiments. For example, in one embodiment, the "first driving device" in other embodiments is referred to as a "second driving device", and correspondingly, the "second driving device" in other embodiments is referred to as a "first driving device".

The fixing frame 611 may be made of a hard material such as plastic, metal, etc. The whole fixing frame 611 may be a frame structure, and of course, may be other shapes, which will not be described in detail. The fixing frame 611 may include a first connection plate 6111, a second connection plate 6112 connected to the first connection plate 6111, a third connection plate 6113 connected to the second connection plate 6112 and disposed opposite to the first connection plate 6111, and a fourth connection plate 6114 connected to the third connection plate 6113 and the first connection plate 6111 and disposed opposite to the second connection plate 6112.

In an embodiment, the first connection plate 6111, the second connection plate 6112, the third connection plate 6113, and the fourth connection plate 6114 may be enclosed to form a rectangle. The extending direction of the second connecting plate 6112 and the extending direction of the fourth connecting plate 6114 may be identical to the extending direction of the bar-shaped hole 1111, or may be different.

The second slide rail assembly 612 is disposed on the fixing frame 611 for enabling the sliding connection of the fixing frame 611 and the frame 10 when the second slide rail assembly 612 is slidably connected with the frame 10, such as the first guide rail 1126. The second rail assembly 612 may include a plurality of rails, and a particular number of rails may be the same as the number of first rails 1126, and in some embodiments, the number of rails may be less than the number of first rails 1126.

In an embodiment, the number of the sliding rails may be 4, which are the first sliding rail 6121, the second sliding rail 6122, the third sliding rail 6123, and the fourth sliding rail 6124, respectively.

Each slide rail, for example, the first slide rail 6121, may include a second slide rail mount 6125 disposed on the mount 611 and a second slide rail member 6126 mounted to the second slide rail mount 6125. Wherein the second rail member 6126 can be mounted to the first rail 1126 to enable relative sliding movement of the second rail member 6126 with respect to the frame 10, such as the first rail 1126.

The second rail mount 6125 may be made from a rigid material such as plastic, metal, or the like. The second sliding rail mounting member 6125 may be fixed on the fixing frame 611 by a screw connection, a plug connection, a welding, a buckle, an adhesive, etc. In an embodiment, the second rail mounting member 6125 may be omitted and the second rail member 6126 may be directly disposed on the fixing frame 611.

When the second slide rail assembly 612 is slidably coupled to the frame 10, such as the first rail 1126, the second slide rail member 6126 of the slide rail, such as the first slide rail 6121, is slidably coupled to the first rail 1126 of the second leg 1122. The second rail member 6126 of the rail, e.g., the second rail 6122, is slidably coupled to the first rail 1126 of the third leg 1123. The second rail member 6126 of a rail, such as the third rail 6123, is slidably coupled to the first rail 1126 of the fourth leg 1124. The second rail member 6126 of the rail, e.g., the fourth rail 6124, is slidably coupled to the first rail 1126 of the first leg 1121.

In an embodiment, the first sliding rail 6121 and the fourth sliding rail 6124 are disposed on a side of the fourth connecting plate 6114 away from the second connecting plate 6112. The second sliding rail 6122 and the third sliding rail 6123 are disposed on a side of the second connecting plate 6112 away from the fourth connecting plate 6114. Of course, as for the mounting positions of the first slide rail 6121, the second slide rail 6122, the third slide rail 6123, and the fourth slide rail 6124 on the fixing frame 611, respectively, can be adjusted according to actual situations.

The second guide 613 is mounted on the fixing frame 611 for mounting the shipper 62 such that the shipper 62 slides on the second guide 613. The second rail 613 may extend in a direction that coincides with the direction of extension of the bar-shaped aperture 1111 such that the shipper 62 slides within the bar-shaped aperture 1111 as well as sliding on the second rail 613. The second rail 613 may include a first sub-rail 6131 disposed on a mount 611, such as a second connection plate 6112, and a second sub-rail 6132 disposed on a mount 611, such as a fourth connection plate 6114. The extending direction of the first sub rail 6131 may coincide with the extending direction of the second sub rail 6132. The first sub-rail 6131 and the second sub-rail 6132 may be fixed on the fixing frame 611 by screwing, buckling, welding, bonding, plugging, etc. In one embodiment, the extending direction of the first sub rail 6131 is a horizontal direction. In an embodiment, the extending direction of the first sub-rail 6131 may be different from the extending direction of the second sub-rail 6132 when the shipper 62 slides over the first sub-rail 6131 without affecting the sliding of the shipper 62 within the bar-shaped aperture 1111.

It will be appreciated that the designations "first rail", "second rail", and "rail" may be interchangeable in some embodiments. For example, in one embodiment, the "first rail" in other embodiments is referred to as the "second rail", and correspondingly, the "second rail" in other embodiments is referred to as the "first rail".

The second driving means 614 may include a second driving member 6141 provided on the fixing frame 611 and a screw 6142 connected to the second driving member 6141. The second driving member 6141 may be mounted on the fixing frame 611, for example, the first connecting plate 6111, for driving the screw 6142 to rotate. The second driving member 6141 may be electrically connected to the control circuit board 40 to move under the control of the control circuit board 40. The screw 6142 is rotatably connected with the fixing frame 611 such as the first connecting plate 6111 and the fourth connecting plate 6114. The extending direction of the lead screw 6142 may coincide with the extending direction of the second guide rail 613. The outer surface of the screw 6142 is provided with external threads. The lead screw 6142 is screwed with the carrying member 62 by an external thread, so that when the lead screw 6142 rotates, the lead screw 6142 rotates relative to the carrying member 62, and the carrying member 62 slides on the second guide rail 613 under the cooperation of the lead screw 6142 and the second guide rail 613.

The second driving member 6141 is installed on one side of the first connecting plate 6111 away from the third connecting plate 6113, and specifically can be connected and fixed through a connection mode such as a screw, a bolt, a buckle, a plug-in connection, a welding connection, an adhesive connection and the like. In an embodiment, the second drive 6141 may be a motor. The output shaft of the motor may penetrate the first connection plate 6111 and be connected to the lead screw 6142. Of course, the second driving member 6141 may be other types of power sources.

It will be appreciated that the second guide rail 613 may be omitted when the number of lead screws 6142 is as large as to maintain, support the stability of the shipper 62.

In some embodiments, a mount 611, such as a first connector plate 6111, is provided with a positioning light generator 615 for positioning the test card in the shipper 62. The positioning light generator 615 is located at a side of the first connection plate 6111 remote from the third connection plate 6113. The positioning light generator 615 is disposed opposite to the positioning holes, such as the positioning hole 576 and the positioning hole 517, on the pressing plate 50, so that the light emitted from the positioning light generator 615 passes through the positioning holes, such as the positioning hole 576 and the positioning hole 517, on the pressing plate 50, and then cooperates with the positioning light receiver 716 (shown in fig. 33) to position the test card on the shipping member 62.

In one embodiment, to limit movement of the shipping member 62, a light sensor 616 may be disposed on a side of the mount 611, such as the second connection plate 6112, proximate to the fourth connection plate 6114. The light sensor 616 is electrically connected to the control circuit board 40 to operate under the control of the control circuit board 40. The light sensor 616 may include a light emitting unit for emitting light and a light receiving unit for receiving light. When the carrying member 62 slides along the second guide rail 613 toward the first connection plate 6111 and reaches a predetermined position, the light emitted from the light emitting unit is received and reflected to the light receiving unit, the light sensor 616 is triggered to generate a control signal and transmit the control signal to the control circuit board 40, and the control circuit board 40 controls the carrying member 62 so that the carrying member 62 is maintained at the predetermined position. In one embodiment, the light sensor 616 is located on a side of the second connection plate 6112 near the first connection plate 6111. In an embodiment, the light sensor 616 may also be limited by the first limit switch 15, the travel switch, the proximity switch, etc. in the above embodiments.

In some embodiments, to enable the pressing plate 50 to slide with the carriage 61, a traction element 617 may be provided on the fixed frame 611. The number of the traction members 617 may be plural in order to achieve stable sliding of the pressing plate 50 and the carriage 61. For example, the number of traction elements 617 may be 2, first traction element 6171 and second traction element 6172, respectively. Two traction elements 617 may be symmetrically disposed on both sides of the mount 611.

In one embodiment, the first traction member 6171 is disposed on a side of the second connecting plate 6112 remote from the fourth connecting plate 6114. The second traction member 6172 is disposed on a side of the fourth connecting plate 6114 away from the second connecting plate 6112.

Each of the traction members 617, for example, the second traction member 6172, may include a suspension member 6172a provided on a connection plate, for example, the fourth connection plate 6114, and an elastic member 6172b having one end connected to the suspension member 6172a and the other end connected to the pressing plate 50, for example, the hanging tab 575. Wherein the tight fit between the mount 611 and the abutment plate 50 is increased by the elastic member 6172b.

In one embodiment, the suspension 6172a can be a columnar structure. The hanging piece 6172a of the first traction piece 6171 is provided on the side of the second connecting plate 6112 away from the fourth connecting plate 6114. The suspension 6172a of the first traction member 6171 can be positioned between the second slide 6122 and the third slide 6123. The suspension 6172a of the second traction member 6172 is provided on a side of the fourth connecting plate 6114 away from the second connecting plate 6112. The suspension 6172a of the second traction member 6172 can be positioned between the first slide 6121 and the fourth slide 6124.

In one embodiment, the elastic member 6172b may be a tension spring. One end of an elastic member 6172b, such as a tension spring, of the first traction member 6171 may be connected and fixed to the suspension member 6172a of the first traction member 6171. The other end of the elastic member 6172b of the first traction member 6171, such as a tension spring, may be connected and fixed with the pressing plate 50, such as the first hanger 5751. One end of an elastic member 6172b, such as a tension spring, of the second traction member 6172 may be connected and fixed to the suspension member 6172a of the second traction member 6172. The other end of the elastic member 6172b of the second traction member 6172, such as a tension spring, may be connected and fixed with the pressing plate 50, such as the second hanger 5752.

It will be appreciated that in some embodiments, the suspension 6172a of each traction element 617 may be omitted, and the corresponding mating resilient element 6172b may be directly connected and secured to the corresponding connection plate in the mount 611. In some embodiments, the traction members 617 may be omitted where the shipper assembly 60 relies on its own weight to effect movement with the pressure plate 50. In some embodiments, the tractor 617 may be omitted and the shipping assembly 60 may be threadably coupled to the lead screw assembly 122, e.g., the first lead screw 1221, the second lead screw 1222.

Referring to fig. 26, fig. 26 is a schematic structural view of the carrying member 62 in fig. 24. The carrying member 62 may include a sliding seat 63 mounted on the second guide rail 613 and screw-coupled with a second driving means 614 such as a screw 6142, a third driving member 64 mounted on the sliding seat 63, and a card holder 65 mounted on the third driving member 64 and driven in a rotational movement by the third driving member 64. The sliding seat 63 slides on the second guide rail 613 to drive the third driving member 64 and the card holder 65 to move together, and can move to a position outside the rack 10 to place the detection card on the card holder 65, the sliding seat 63 can also drive the third driving member 64 and the card holder 65 to move to a position in the rack 10, and the third driving member 64 can drive the detection card on the card holder 65 to perform centrifugal movement to complete the centrifugal processing of the detection card.

Referring to fig. 27 and 28, fig. 27 and 28 are schematic views of the sliding seat 63 of fig. 26 from different angles. The slide mount 63 may include a slide mount body 631 for mounting the third driver 64, a third slide rail assembly 632 disposed on the slide mount body 631 and slidably coupled to the second rail 613, e.g., the first sub rail 6131, and a fourth slide rail assembly 633 disposed on the slide mount body 631 and slidably coupled to the second rail 613, e.g., the second sub rail 6132. The fourth rail assembly 633 can be screwed to a second drive 614, such as a threaded spindle 6142. So as to drive the sliding seat body 631 to slide on the second guide rail 613 under the driving of the second driving device 614.

The slide mount body 631 may be made of a hard material such as plastic, metal, or the like. The slide mount body 631 may include a bottom plate 6311 and a side plate 6312 surrounding the bottom plate 6311. The middle portion of the bottom plate 6311 may be provided with a yielding hole 6311a to yield the third driving member 64. The side plate 6312 may extend from the edge of the bottom plate 6311 to a side away from the pressing plate 50. The side plates 6312 may include a first side plate 6312a provided with the third slide rail assembly 632, a second side plate 6312b connected with the first side plate 6312a and located at a side of the bottom plate 6311 near the first connection plate 6111, and a third side plate 6312c connected with the second side plate 6312b and symmetrically provided with the first side plate 6312 a.

The third sliding rail assembly 632 is fixed on the side of the first side plate 6312a near the second connecting plate 6112, which may be specifically fixed by screwing, inserting, fastening, welding, bonding, or the like. The third slide rail assembly 632 is slidably coupled with the second rail 613, e.g., the first sub rail 6131, to achieve a sliding connection of the slide mount body 631 with the slide frame 61. The third rail assembly 632 may include a third rail mount 6321 provided on the slide mount body 631, for example, the first side plate 6312a, and a third rail piece 6322 mounted on the third rail mount 6321. Wherein the third track member 6322 may be mounted on a second track 613, e.g. a first sub-track 6131, to enable relative sliding movement of the third track member 6322 and the second track 613, e.g. the first sub-track 6131.

The third track mount 6321 may be made of a rigid material such as plastic, metal, or the like. The third rail mount 6321 may be secured to the side plate 6312, e.g., the first side plate 6312a, by screwing, plugging, snapping, welding, bonding, etc. In an embodiment, the third rail mount 6321 may be omitted and the third rail mount 6322 may be disposed directly on the side plate 6312, e.g., the first side plate 6312 a.

The fourth sliding rail assembly 633 is fixed on a side of the third side plate 6312c near the fourth connecting plate 6114, and may specifically be fixed by screwing, inserting, fastening, welding, bonding, or other manners. The fourth rail assembly 633 is slidably coupled to a second rail 613, such as a second sub-rail 6132, to provide for a sliding connection of the slide mount body 631 to the slide mount 61. The fourth rail assembly 633 may include a fourth rail mount 6331 provided on the slide mount body 631, for example, the third side plate 6312c, a fourth rail piece 6332 mounted on the fourth rail mount 6331, and a screw 6333 mounted on the fourth rail mount 6331. Wherein the fourth track member 6332 may be mounted on a second track 613, e.g. a second sub-track 6132, to enable relative sliding movement of the fourth track member 6332 and the second track 613, e.g. the second sub-track 6132. The screw 6333 may be sleeved on the screw 6142, and an internal thread matching with an external thread of the screw 6142 is provided inside the screw 6333, so that the sliding seat 63 moves in an extending direction of the screw 6142 under the driving of the second driving member 6141.

It will be appreciated that the designations "first slide", "second slide", "third slide", "fourth slide", and "slide", etc., may be interchanged in some embodiments. For example, in one embodiment, the "first rail" in other embodiments is referred to as the "second rail", and correspondingly, the "second rail" in other embodiments is referred to as the "first rail".

The designations of "first slide rail assembly", "second slide rail assembly", "third slide rail assembly", "fourth slide rail assembly", and "slide rail assembly" may be interchangeable in some embodiments. For example, in one embodiment, the "first slide rail assembly" in other embodiments is referred to as the "second slide rail assembly", and correspondingly, the "second slide rail assembly" in other embodiments is referred to as the "first slide rail assembly".

The designations of "first rail mount", "second rail mount", "third rail mount", "fourth rail mount", and "rail mount" may be interchangeable in some embodiments. For example, in one embodiment, the "first rail mount" in other embodiments is referred to as a "second rail mount", and correspondingly, the "second rail mount" in other embodiments is referred to as a "first rail mount".

The designations of "first rail member", "second rail member", "third rail member", "fourth rail member", and "rail member" may be interchangeable in some embodiments. For example, in one embodiment, the "first rail member" in other embodiments is referred to as the "second rail member", and correspondingly, the "second rail member" in other embodiments is referred to as the "first rail member".

The fourth track mount 6331 may be made of a rigid material such as plastic, metal, or the like. The fourth rail mount 6331 may be secured to the side plate 6312, e.g., the third side plate 6312c, by screwing, plugging, snapping, welding, bonding, etc. In an embodiment, the fourth track mount 6331 may be omitted and the fourth track mount 6332 may be disposed directly on the side plate 6312, e.g., the third side plate 6312 c.

The screw 6333 may be disposed between the side plates 6312, e.g., the third side plate 6312c and the fourth slide mount 6331.

In one embodiment, limiting the slide mount 63 is achieved. The sliding seat 63 is provided with a first stopper 634. The first limiting member 634 may be disposed on a portion of the second side plate 6312b corresponding to the light sensor 616, so that when the sliding seat 63 slides along the second guide rail 613 toward the first connecting plate 6111, the light emitted from the light emitting unit may be received when the sliding seat 63 reaches a predetermined position, the first limiting member 634 reflects the light to the light receiving unit, the light sensor 616 generates a control signal and transmits the control signal to the control circuit board 40, and the control circuit board 40 controls the second driving member 6141. So that the slide mount 63 is located at a predetermined position. It will be appreciated that the first stop 634 may also be located at other locations where it may cooperate with the light sensor 616, such as the third drive member 64.

In addition, the slide seat 63 is limited. The sliding seat 63 is provided with a second limit piece (not shown) cooperating with the first limit switch 15. When the sliding seat 63 moves to a side far away from the first connecting plate 6111 and reaches a predetermined position, the second limiting member can be placed in a groove of the first limiting switch 15, such as a groove-shaped optocoupler, to block light transmission between the limiting light emitting portion and the limiting light receiving portion, so that the first limiting switch 15, such as the groove-shaped optocoupler, is triggered to generate a control signal and transmit the control signal to the control circuit board 40, and under the control of the control circuit board 40, the operation of the second driving member 6141 is stopped, and further, the movement of the sliding seat 63 is stopped. It will be appreciated that the second stop member may also be provided at other locations where it may cooperate with the first stop switch 15, such as the third drive member 64.

It will be appreciated that the designations "first stop", "second stop" and "stop" may be interchangeable in some embodiments. For example, in one embodiment, the "first stopper" in other embodiments is referred to as the "second stopper", and correspondingly, the "second stopper" in other embodiments is referred to as the "first stopper".

Referring again to fig. 26 and 27, the third driving member 64 is mounted on a sliding seat 63, such as a base plate 6311. The side plate 6312 surrounds the third drive member 64. The third driving member 64 may be specifically connected and fixed to the sliding seat 63 by screwing, plugging, buckling, welding, bonding, etc. A part of the structure of the third driving member 64, such as the output shaft, may pass through the relief hole 6311a and be connected and fixed to the card holder 65. In one embodiment, the third drive member 64 may be a motor. The output shaft of the motor may pass through the relief hole 6311a and be connected to the catch 65.

It will be appreciated that the designations of "first drive", "second drive", "third drive", and "drive" etc. may be interchangeable in some embodiments. For example, in one embodiment, the "first driver" in other embodiments is referred to as the "second driver", and correspondingly, the "second driver" in other embodiments is referred to as the "first driver".

The clamping support 65 is arranged below the sliding seat 63 and is fixedly connected with the third driving piece 64.

Referring to fig. 29 and 30, fig. 29 is a schematic structural view of the connection between the third driving member 64 and the clamping bracket 65 in fig. 26, and fig. 30 is a schematic structural view of the connection between the third driving member 64 and the clamping bracket 65 and the compression member 53 in fig. 2. The tray 65 may include a tray body 651. The card holder body 651 may be made of a rigid material such as plastic, metal, etc. The holder main body 651 is a rotation body, and the axis of the rotation body is coaxially provided with the output shaft of the third driving element 64. In one embodiment, the cartridge body 651 is a circular disk-like structure.

The holder main body 651 is provided with ribs 652 on a side close to the third driving member 64. The rib 652 is disposed so as to diverge around the portion of the holder main body 651 connected to the third driving element 64. The ribs 652 are circumferentially distributed around the portion of the holder body 651 to which the third driving member 64 is connected.

Adjacent two ribs 652 form a recess 653 with the card holder body 651 for placement of a test card. The number of recesses 653 may correspond to the number of heating elements 54. Of course, the number of the concave portions 653 may be smaller than the number of the heating elements 54. In one embodiment, the number of the concave portions 653 may be 6, and of course, the specific number of the concave portions 653 may be adjusted according to practical situations.

The holder body 651 is provided with a second clamping portion 654 in the recess 653 for clamping with the test card. The second clamping portion 654 is located near the edge of the clamping body 651. In one embodiment, the second fastening portion 654 is a groove or a protrusion. The card holder body 651 provides a receiving hole 655 in the recess 653 to allow for the detection card. In one embodiment, the recess 653 is a groove that may have the same depth as the thickness of the test card so that when the test card is placed in the recess 653, the surface of the test card is flush with the surface of the rib 652 remote from the card holder body 651.

In one embodiment, to effect connection of the cartridge body 651 with the hold down 53. The third clamping portion 6521 may be disposed on the rib 652, so that the third clamping portion 6521 is clamped with the pressing member 53. In an embodiment, the third clamping portion 6521 is a protruding pillar, so that the protruding pillar is disposed in the first clamping portion 5314 of the pressing member 53, for example, in the connecting hole, and is clamped with the pressing member 53. In one embodiment, the first clamping portion 5314 may be disposed on the rib 652 and the third clamping portion 6521 may be disposed on the pressing member 53. In an embodiment, the snap-fit relationship between the third locking portion 6521 and the pressing member 53 may be replaced by other structures, such as a groove and a protrusion, a socket structure, a snap structure, etc. In an embodiment, to further enhance the mating relationship between the card holder main body 651 and the pressing member 53, a magnetic force connecting member such as a permanent magnet or an electromagnet may be disposed inside the card holder main body 651 and/or the rib 652, so as to absorb the pressing member 53 by using the magnetic force, and enhance the mating relationship between the third clamping portion 6521 and the pressing member 53, so that the pressing member 53 may abut against the surface of the detection card, so as to avoid unstable installation of the detection card.

In one embodiment, to achieve positioning of the test card. The rib 652 may be provided with a positioning hole 6522. The positioning hole 6522 is opposite to the positioning hole 517, 576 when the card holder body 651 is rotated to a predetermined position, so that when the light emitted from the positioning light generator 615 passes through the positioning hole 517, 576 and 6522, it is confirmed that the detection card on the card holder body 651 is at the predetermined position, and if the light emitted from the positioning light generator 615 passes through the positioning hole 517 and 576 when the card holder body 651 is not rotated to the predetermined position, it is confirmed that the detection card on the card holder body 651 is not at the predetermined position, but does not pass through the positioning hole 6522.

In one embodiment, the card holder body 651 is provided with a first positioning member 656 (shown in fig. 31) on a side remote from the third driving member 64 to position the test card when the test card is carried to the test card holder 30 so that the test card is placed at a predetermined position for test card detection. In an embodiment, the first positioning member 656 is a positioning block, and the positioning block extends to a side far away from the card holder main body 651, and the cross-sectional area perpendicular to the extending direction gradually decreases. In one embodiment, the positioning block may be conical.

It will be appreciated that the carrier body 651 may be in the fourth position when the test card is carried by the card holder body 651 to the test card test socket 30.

It will be appreciated that the designations "first position", "second position", "third position", "fourth position", and "position" may be interchangeable in some embodiments. For example, in one embodiment, the "first position" in other embodiments is referred to as the "second position", and correspondingly, the "second position" in other embodiments is referred to as the "first position".

Fig. 31 and 32 are schematic views of the connection structure of the pressing plate 50 and the shipping assembly 60 of fig. 2 according to different views of the present application. When the pressure plate 50 is connected to the shipping assembly 60, the components of the shipping assembly 60 with the clip 65 removed are assembled together, and then the carriage 61 of the shipping assembly 60 is placed over the pressure plate 50. The first slide rail 6121 in the carriage 61 is disposed opposite the fourth slide rail 584 of the pressure plate 50 so as to be mounted together on the first rail 1126 of the second leg 1122 of the frame 10. The second slide rail 6122 in the carriage 61 is disposed opposite the first slide rail 581 of the pressing plate 50 so as to be mounted together on the first guide rail 1126 of the third leg 1123 of the frame 10. The third slide rail 6123 in the slide frame 61 is disposed opposite the second slide rail 582 of the pressing plate 50 so as to be mounted together on the first guide rail 1126 of the fourth leg 1124 of the frame 10. The fourth slide rail 6124 in the slide frame 61 is disposed opposite the third slide rail 583 of the pressing plate 50 so as to be mounted together on the first rail 1126 of the first leg 1121 of the frame 10.

It will be appreciated that the pressure plate 50 and the shipping assembly 60 may also be mounted on different first rails 1126, respectively. Of course, portions of the first rail 1126 may be mounted only against the platen 50 or the shipping assembly 60.

Next, the card holder 65 of the shipping member 62 in the shipping assembly 60 is placed on the side of the pressing plate 50 away from the carriage 61, so that the pressing member 53 is located between the first housing 51 and the card holder 65. The output shaft of the third driving member 64 of the delivery member 62 in the delivery assembly 60 passes through the notch of the pressing plate 50 and is connected and fixed with the clamping bracket 65.

The first lugs 5751 of the abutment plate 50 are disposed opposite and interconnected to the first traction members 6171 in the shipping assembly 60. The second lugs 5752 of the abutment plate 50 are disposed opposite and interconnected to the second traction members 6172 in the shipping assembly 60. Specifically, one end of the elastic member 6172b of the first traction member 6171 is connected to the suspension member 6172a of the first traction member 6171, and the other end of the elastic member 6172b of the first traction member 6171 is connected to the first hanger 5751 of the pressure plate 50. One end of the elastic member 6172b of the second traction member 6172 is connected to the suspension member 6172a of the second traction member 6172, and the other end of the elastic member 6172b of the second traction member 6172 is connected to the first hanger 5751 of the pressing plate 50.

Detection card detection seat 30

Referring to fig. 33, fig. 33 is an exploded view of the test card holder 30 in fig. 2. The test card test socket 30 may include a support frame 70 fixedly connected to the frame 10, a support seat 80 mounted on the support frame 70, and a test assembly 90 mounted on the support frame 70 and the support seat 80. Wherein the support base 80 is located below the pressing plate 50 so as to carry the test card conveyed by the test card conveying base 20, such as the delivery assembly 60. The detection assembly 90 is electrically connected to the control circuit board 40. When the detection module 90 places the detection card on the support base 80, a series of detection processes are performed on the detection card by using the excitation light to generate a detection signal, and the detection signal is transmitted to the control circuit board 40.

Support frame 70

Referring to fig. 33, the support frame 70 is integrally formed as a frame structure and may be located at the bottom of the frame 10. The support frame 70 may include a base 71 disposed at the bottom of the frame 10 and fixedly connected to the frame 10, and a fixing seat 72 mounted at the top of the base 71.

The base 71 may include a base body 711. The base body 711 may be made of a rigid material such as plastic, metal, or the like. The whole base body 711 may have a plate-like structure, but may have other structures, and the details thereof will not be described. The base 71 may be attached to the frame 10, such as the leg 112, by plugging, screwing, welding, bonding, snapping, etc. In one embodiment, the base 71 may be secured to the ends of the legs 112.

A fixing groove 712 may be formed in the middle of the top of the base body 711 for receiving and fixing the fixing seat 72. In an embodiment, the fixing groove 712 may be omitted, and the fixing base 72 may be directly fixed on the base 71.

The base body 711 has a plurality of isolation grooves 713 circumferentially distributed around the fixing groove 712 to cooperate with the detecting member 90. A fixing portion 714 is formed between adjacent two of the isolation grooves 713 to be engaged with the detecting assembly 90. The provision of the plurality of isolation grooves 713 may reduce the contact area of the sensing element 90 with the base body 711. In an embodiment, the isolation groove 713 may be omitted.

The top of the base body 711 is provided with a support part 715 for supporting the support base 80. The support portion 715 may be connected and fixed to the base body 711 by plugging, screwing, welding, bonding, fastening, or the like. In an embodiment, the supporting portion 715 may have a rod-shaped structure, and of course, the supporting portion 715 may have other structures. In an embodiment, the support 715 may be omitted in the case of other structures supporting the support base 80.

The top of the base body 711 is provided with a positioning light receiver 716 opposite to the positioning light generator 615, so as to receive light emitted by the positioning light generator 615, thereby realizing positioning of the detection card. The positioning light receiver 716 may be electrically connected to the control circuit board 40 such that, after the positioning light receiver 716 receives the light, a signal is generated and transmitted to the control circuit board 40 to cause the molecular diagnostic device 100 to confirm that the detection card has reached a predetermined position. In some embodiments, the mounting locations of the positioning light generator 615 and the positioning light receiver 716 may be interchanged.

The mounting block 72 may include a mounting block 721 disposed within the mounting slot 712. The mounting 721 may be made of a rigid material such as plastic, metal, etc. The mounting base 721 may be fixed to the base body 711 by plugging, screwing, welding, bonding, fastening, or the like. The mounting block 721 may be used to mount the detection assembly 90.

The top of the mount 721 may be provided with first and second clamping plates 722 and 723, which are vertically disposed. The first and second clamping plates 722, 723 may each be made of a rigid material such as plastic, metal, or the like. The first and second clamping plates 722, 723 are offset and disposed in parallel to mate with the detection assembly 90. The first clamping plate 722 is provided with a fixing hole 7221 to be engaged with the sensing assembly 90. The second clamping plate 723 is provided with fixing holes 7231 to be engaged with the detection assembly 90. The extending direction of the fixing hole 7221 is parallel to the extending direction of the fixing hole 7231 without overlapping, so that a compact installation of the detecting assembly 90 is achieved. It will be appreciated that in one embodiment, the mounting block 721 may be omitted and the first and second clamping plates 722, 723 may be mounted directly to the base body 711.

A support plate 724 is provided on the first and second clamping plates 722 and 723 for supporting the support base 80. The support plate 724 is disposed opposite the mount 721.

In one embodiment, at least a portion of the structure in the support frame 70, such as the base 71, may also be part of the frame 10. That is, the support frame 70 may also be part of the frame 10.

Support base 80

Referring to fig. 34, fig. 34 is an exploded view of the support base 80 shown in fig. 33. The support base 80 may include a support base body 81 mounted on the base 71 such as the support portion 715 and the support plate 724, a detection chamber assembly 82 mounted on the support base body 81, a loading chamber assembly 83 mounted on the support base body 81 and supporting a detection card in cooperation with the detection chamber assembly 82, and a second circuit board 84 provided on the support base body 81. Wherein the detection chamber assembly 82 may be mounted on the support base 80 at a position opposite to the heating assembly 54, for example, the first heating element 541, to be engaged with the heating assembly 54, for example, the first heating element 541. The loading chamber assembly 83 can be mounted on the support base 80 opposite the heating assembly 54, such as the second heating member 542, to mate with the heating assembly 54, such as the second heating member 542. The detection chamber assembly 82 cooperates with the loading chamber assembly 83 to support and heat the detection card. The detection chamber assembly 82 may also be used to detect excitation light from a detection card. The detection chamber assembly 82 and the loading chamber assembly 83 are electrically connected together with the second circuit board 84 to realize heating control of the detection chamber assembly 82 and the loading chamber assembly 83.

Referring to fig. 35 and 36, fig. 35 and 36 are schematic views of the supporting seat body 81 of fig. 34 from different angles. The support base body 81 may be made of a rigid material such as plastic, metal, etc. The support base body 81 may have a plate-like structure as a whole. The top of the supporting seat body 81 may be provided with a placement groove 811 for giving way to the card holder 65. The support base body 81 has a clamping hole 812 formed in the placement groove 811 for engagement with the loading chamber assembly 83. The supporting seat main body 81 is further provided with a second positioning member 813 in the placement groove 811 to cooperate with the first positioning member 656 to position the detection card. In an embodiment, the second positioning member 813 may be a positioning groove formed in the placement groove 811 of the supporting seat body 81, so as to be used for positioning the position of the test card when the first positioning member 656, for example, a positioning block, is placed in the second positioning member 813, for example, a positioning groove. In an embodiment, the shape of the second positioning member 813, e.g., a positioning block, may match the shape of the first positioning member 656, e.g., a positioning slot. It can be understood that the positioning and matching relationship between the supporting seat main body 81 and the clamping bracket 65 is not limited to the matching relationship between the second positioning member 813 and the first positioning member 656, but may be a matching relationship between magnets, a matching relationship between an electromagnet and a magnetic force, or other matching relationships, which will not be repeated.

It will be appreciated that the designations of "first detent", "second detent", and "detent" may be interchangeable in some embodiments. For example, in one embodiment, the "first positioning member" in other embodiments is referred to as the "second positioning member", and correspondingly, the "second positioning member" in other embodiments is referred to as the "first positioning member".

The support base body 81 is provided with a positioning hole 814 in the placement groove 811. The positioning hole 814 may be disposed opposite to the positioning hole 517, the positioning hole 576 and the positioning hole 6522, so that the light emitted from the positioning light generator 615 passes through the positioning hole 814, the positioning hole 517, the positioning hole 576 and the positioning hole 6522 and is received by the positioning light receiver 716 to position the detection card.

The support base body 81 has a plurality of extending grooves 815 uniformly distributed around the circumference of the placement groove 811. The extending grooves 815 are communicated with the placing grooves 811, so that the supporting seat main body 81 forms an assembling table 816 between two adjacent extending grooves 815, a detection card can be placed on the assembling table 816, and the extending grooves 815 give way to the detection card, so that the assembling table 816 supports and clamps the detection card.

The support base body 81 is provided with a receiving hole 817 at a position of the mounting table 816 so that the detection chamber assembly 82 is mounted in the receiving hole 817.

The support base body 81 is provided with a recess 818 at a position adjacent to one side of the support frame 70 and opposite to the mounting table 816 for mounting the detection chamber assembly 82. The receiving hole 817 is located in the recess 818. A mounting stand 819 is positioned between adjacent recesses 818 for securing the detection chamber assembly 82.

Referring to fig. 34, the detection chamber assembly 82 is mounted in the support base body 81, such as the accommodating hole 817 and the recess 818. The detection chamber assembly 82 may include at least one light detection member 821, and a specific number of light detection members 821 may be one of 1, 2, 3, 4, 5, 6, … … to facilitate mounting of the detection chamber assembly 82 within the recess 818.

Referring to fig. 37, fig. 37 is a schematic structural diagram of the light detecting member 821 in fig. 34. The light detecting member 821 may be provided in correspondence with one of the first heating members 541 so that both cooperate to heat one of the detecting cards. The light detecting member 821 may include a detecting seat 822 disposed in the supporting seat body 81, for example, the receiving hole 817 and the recess 818, and a first clamping piece 823 for fixing the detecting seat 822 to the supporting seat body 81.

Referring to FIGS. 37 and 38, FIG. 38 is a cross-sectional view of sensing seat 822 of FIG. 37 taken along line XXXVII-XXXVII. The test seat 822 may include a test seat body 8221 disposed within a support seat body 81, such as a recess 818. The detection seat main body 8221 may be made of a hard material such as plastic, metal, or the like. The detection seat main body 8221 is provided with an extension portion 8222 extending toward one side of the receiving hole 817 such that the extension portion 8222 protrudes into the receiving hole 817. The extension portion 8222 is flush with the surface of the mounting table 816 on the side of the mount main body 81 where the mounting table 816 is disposed, so as to improve the external appearance of the mount 80.

The extension portion 8222 is provided with a detection groove 8223 so that a part of the structure of the detection card is placed in the detection groove 8223 at the side where the mount table 816 is provided to the support base main 81.

In one embodiment, the extension 8222 is provided with a separation slot 8224 on the side of the detection slot 8223 adjacent to the loading chamber assembly 83, such that a portion of the structure of the detection card is disposed within the separation slot 8224 on the side of the support base body 81 where the mounting table 816 is disposed.

The detection groove 8223 extends from the extension portion 8222 toward the detection seat main body 8221.

The detection seat main body 8221 is provided with an excitation fiber channel 8225 in the extending direction of the detection groove 8223 for mounting the excitation fiber 8226. The excitation fiber channel 8225 communicates with the detection slot 8223 such that the excitation fiber 8226 emits light, such as excitation light, to the detection slot 8223. In one embodiment, the extension direction of the excitation fiber channel 8225 may coincide with the extension direction of the detection slot 8223. In an embodiment, the extension direction of the excitation fiber channel 8225 may form an angle with the extension direction of the detection groove 8223, and the degree of the angle may be 0-75 °. In one embodiment, the excitation fiber channel 8225 is sloped from the detection slot 8223 to the loading chamber assembly 83 side.

In an embodiment, the excitation fiber channel 8225 is inclined from the detection slot 8223 to the loading chamber component 83, and the extending direction of the excitation fiber channel 8225 may form an included angle with the extending direction of the detection slot 8223, and the degree of the included angle may be one of 0, 15 °, 30 °, 45 °, 60 °, 75 °.

The excitation fiber 8226 may include an excitation fiber body 8226a and an excitation fiber nipple 8226b disposed at an end of the excitation fiber body 8226 a. Wherein an excitation fiber splice 8226b is disposed within excitation fiber channel 8225. The junction of the excitation fiber body 8226a and the excitation fiber nipple 8226b forms a securing location for mating with the first clamp tab 823.

In one embodiment, the excitation fiber 8226, e.g., excitation fiber body 8226a, has a diameter of about 2.5mm. Specifically, the diameter may be 2.5mm.

The detection seat main body 8221 is provided with a receiving fiber channel 8227 communicating with the detection groove 8223 at a position forming an angle with the extending direction of the detection groove 8223. The receiving fiber 8228 is used for receiving excitation light emitted from the excitation fiber 8226 and fluorescence formed by the excitation light irradiation detection card.

In an embodiment, the extending direction of the receiving fiber channel 8227 may form an angle with the extending direction of the detection slot 8223, and the degree of the angle may be 0-75 °. In one embodiment, the excitation fiber channel 8225 is sloped from the detection slot 8223 to a side distal to the loading chamber assembly 83.

In an embodiment, the receiving fiber channel 8227 is inclined from the detection slot 8223 to a side far away from the loading chamber assembly 83, the extending direction of the receiving fiber channel 8227 may form an included angle with the extending direction of the detection slot 8223, and the degree of the included angle may be one of 0, 15 °, 30 °, 45 °, 60 °, 75 °.

In one embodiment, the excitation fiber channel 8225 is inclined from the detection slot 8223 to the loading chamber assembly 83, and the extension direction of the excitation fiber channel 8225 may form an angle with the extension direction of the detection slot 8223, and the degree of the angle may be 45 °. The receiving fiber channel 8227 is inclined from the detecting groove 8223 to a side far from the loading cavity assembly 83, the extending direction of the receiving fiber channel 8227 can form an included angle with the extending direction of the detecting groove 8223, and the degree of the included angle can be 75 degrees. That is, the direction of extension of the receiving fiber channel 8227 may form an angle with the direction of extension of the excitation fiber channel 8225, and the degree of the angle may be 120 °. The signal to noise ratio of the optical detection element 821 may be up to 80dB or more.

In one embodiment, the extension direction of the excitation fiber channel 8225 may coincide with the extension direction of the detection slot 8223. The receiving fiber channel 8227 is inclined from the detecting groove 8223 to a side far from the loading cavity assembly 83, the extending direction of the receiving fiber channel 8227 can form an included angle with the extending direction of the detecting groove 8223, and the degree of the included angle can be 60 degrees. That is, the direction of extension of the receiving fiber channel 8227 may form an angle with the direction of extension of the excitation fiber channel 8225, and the degree of the angle may be 60 °. The signal to noise ratio of the optical detection element 821 may be up to 60dB or more.

The detection seat main body 8221 is provided with a heating element accommodation groove 8229a at one side where the excitation fiber channel 8225 is provided, for accommodating heating elements such as a heating resistor. The detection seat main body 8221 can realize heating of the detection card through a heating device. The heat generating device in the heating member receiving groove 8229a may be electrically connected to the second circuit board 84 to achieve heating under the control of the second circuit board 84.

The detection seat main body 8221 is provided with a heating element accommodation groove 8229b on a side close to the sample application chamber assembly 83 for accommodating a heating element such as a heating resistor. The detection seat main body 8221 can realize heating of the detection card through a heating device. The heat generating device in the heating member receiving groove 8229b may be electrically connected to the second circuit board 84 to achieve heating under the control of the second circuit board 84.

In an embodiment, the detecting seat main body 8221 may be integrally formed with the supporting seat main body 81.

Referring to fig. 37, the first fastening plate 823 may be made of a hard material such as plastic, metal, etc. The first clamp plate 823 may include a clamp body 8231. The clamping body 8231 can be in a strip-shaped plate structure, and of course, can also be in other structures, and details are omitted. The middle part of the clamping body 8231 can be abutted with one side of the detection seat 822, such as the detection seat main body 8221, where the excitation fiber channel 8225 is arranged. The two ends of the clamping body 8231 are provided with fixing parts 8232 so as to be respectively installed and fixed with the mounting tables 819 on two sides of the detection seat 822, such as the detection seat main body 8221, and specifically, the clamping body can be fixedly connected by adopting modes of plugging, buckling, welding, bonding and the like. The edge of the middle part of the clamping body 8231 is provided with a plurality of clamping holes 8233 so as to give way to the excitation optical fiber 8236. The clamping body 8231 forms a latch 8234 between two adjacent clamping holes 8233. The clamping body 8231 is abutted against one side of the excitation fiber channel 8235 arranged on the detection seat 822, such as the detection seat main body 8231, so that the excitation fiber connector 8236 b is clamped in the excitation fiber channel 8235 by two adjacent clamping teeth 8234, and the excitation fiber body 8236 a is located between the two adjacent clamping teeth 8234. The fixing of the light detecting element 821 is realized.

In one embodiment, to provide a way for the heating element receiving slot 8239 a, the chucking body 8231 is provided with a through hole 8235 at a position opposite to the heating element receiving slot 8239 a so that the heating element protrudes from the through hole 8235 into the heating element receiving slot 8239 a.

Referring to FIGS. 39 and 40, FIG. 39 is a schematic diagram of the loading chamber assembly 83 of FIG. 34. FIG. 40 is a cross-sectional view of the loading chamber assembly 83 of FIG. 39 taken along line XXXIX-XXXIX. The loading chamber assembly 83 may include a tray 831 secured to a support plate 724, a support assembly 832 mounted to the tray 831, and a loading chamber mount 833 mounted to the support assembly 832. Wherein, the loading cavity mount pad 833 is used for fixed detection card, also is used for heating the detection card. The loading chamber mount 833 cooperates with a heating assembly 54, such as a second heating element 542, to heat the test card.

The carrier 831 can be made of a rigid material such as plastic, metal, etc. The whole structure can be plate-shaped, of course, can also be other structures, and the description is omitted. The support plate 831 can be fastened to the support plate 724 by screwing, plugging, bonding, welding, or the like. In one embodiment, the supporting plate 831 can be fastened to the supporting base 81 by screwing, inserting, bonding, welding, etc. In an embodiment, the pallet 831 can be omitted and the support member 832 can be directly fixedly coupled to the support plate 724. In an embodiment, in the case where the support plate 724 is omitted, the supporting plate 831 may be directly fixed to the first and second clamping plates 722 and 723. In an embodiment, the supporting plate 831 may be fixed to the supporting portion 715 while the supporting plate 724 is omitted.

The support assembly 832 may include a socket post 8321 disposed on a side of the tray 831 remote from the support plate 724 and a spring 8322 sleeved on the socket post 8321. One end of the spring 8322 is abutted with the supporting plate 831, and the other end is abutted with the loading cavity mounting seat 833 so as to be used for adjusting the distance between the loading cavity mounting seat 833 and the supporting plate 831. In one embodiment, the socket post 8321 may be omitted. In one embodiment, the spring 8322 may be replaced by an elastic member made of other materials and having elasticity. In one embodiment, the socket posts 8321 may be part of the pallet 831. In one embodiment, a socket post 8321 may be provided on the loading chamber mount 833. In one embodiment, the spring 8322 may be replaced with other elastic members such as plastic, torsion springs, metal strips with elastic deformation, etc.

The loading chamber mount 833 is used for placing the test card. The loading chamber mount 833 may include a mount body 8331. The whole mounting seat body 8331 can be made of hard heat conductive materials such as plastic or metal.

The mounting base body 8331 is configured to be placed in the supporting base body 81, for example, the fastening hole 812, so as to slide in the fastening hole 812. One side of the mounting seat body 8331 far away from the supporting plate 831 is provided with a sample adding cavity mounting groove 8332 for mounting the detection card. The mounting seat body 8331 is provided with a socket 8333 towards the support component 832, so as to be abutted with the mounting seat body 8331 when the spring 8322 is placed in the socket 8333. In one embodiment, the socket 8333 may be omitted.

The edge of mount pad body 8331 towards supporting component 832 one side sets up joint along 8334 to mount pad body 8331 stretches into in the card solid hole 812 from supporting seat main part 81 towards supporting component 832 one side, avoids mount pad body 8331 to keep away from supporting component 832 one side and supporting seat main part 81 slippage at supporting seat main part 81.

The mounting seat body 8331 is provided with a heating element accommodating groove 8335 so as to accommodate heating elements such as a heating resistor, and the like, so that the mounting seat body 8331 can heat the detection card. The heat generating device may be electrically connected to the second circuit board 84 to heat under the control of the second circuit board 84. In one embodiment, the heating element receiving recess 8335 is located between the socket recess 8333 and the loading chamber receiving recess 8332.

In order to better heat the detection card, the detection flow is prevented from being influenced by the heated water vapor condensation, and the detection precision is improved. The mounting seat body 8331 is provided with an abutment portion 8336 at one side edge of the sample loading cavity mounting groove 8332 so as to abut against the detection card. In an embodiment, the abutment 8336 may also be used to position the test card.

Referring to fig. 34, the second circuit board 84 may be electrically connected to the heat generating device in the detection chamber assembly 82 and the heat generating device in the sample application chamber assembly 83, respectively, so as to control the heat generating device to heat.

The second circuit board 84 may have a ring-like structure and may be disposed around the loading chamber assembly 83. The second circuit board 84 may be directly fixed to a side of the support base body 81 near the support frame 70, such as the support plate 724, for example, by welding, inserting, fastening, bonding, screwing, or the like. In one embodiment, the second circuit board 84 may also be directly secured to the support frame 70, such as support plate 724. In an embodiment, the second circuit board 84 may also be directly fixed to the support frame 70, such as the support portion 715. In one embodiment, the second circuit board 84 may also be directly attached to the loading chamber assembly 83, such as the tray 831.

It will be appreciated that the designations "first circuit board", "second circuit board", and "circuit board" may be interchangeable in some embodiments. For example, in one embodiment, the "first circuit board" in other embodiments is referred to as the "second circuit board", and correspondingly, the "second circuit board" in other embodiments is referred to as the "first circuit board".

In an embodiment, the second circuit board 84 may be omitted without sharing the working pressure for the control circuit board 40, and the heat generating device in the detection chamber assembly 82 and the heat generating device in the sample application chamber assembly 83 may be directly electrically connected to the control circuit board 40.

Detection assembly 90

Please refer to fig. 33. The detection assembly 90 may include a light generator 91 mounted on a support frame 70, such as a base body 711, a light receiving assembly 92 mounted on a support frame 70, such as a base body 711, and a detection chamber assembly 82 mounted on a support base 80, such as a support base body 81 (i.e., the detection chamber assembly 82 of the support base 80 described above, the detection chamber assembly 82 may be a common element of the support base 80 and the detection assembly 90). Wherein, the light generator 91 and the light receiving component 92 are electrically connected with the control circuit board 40. The light generator 91 is used to generate excitation light, and may generate the excitation light under the control of the control circuit board 40. The excitation light may be transmitted to the detection cavity assembly 82 to excite the detection card and generate fluorescence, which may be received by the light receiving assembly 92, and the light receiving assembly 92 may generate a detection signal under the control of the control circuit board 40. The detection signal is transmitted to the control circuit board 40 and the control circuit board 40 processes the generated diagnostic data.

Referring to fig. 33 and 41 together, fig. 41 is a schematic diagram of the light generator 91 in fig. 33. The number of the light generators 91 may be 1 or more. The number of light generators 91 may specifically be one of 2, 3, 4, 5, 6, … …. In an embodiment, the number of light generators 91 may be 2, specifically the first light generator 911 and the second light generator 912.

The first light generator 911 and the second light generator 912 may be fixed to the fixed base 72, such as the mounting base 721, and may be fixed to the fixed base 72, such as the mounting base 721, by plugging, welding, screwing, bonding, fastening, or the like. The excitation light output end of the first light generator 911 may pass through the fixing hole 7221 to be fixed on the first clamping plate 722. The excitation light output end of the second light generator 912 may pass through the fixing hole 7231 to be fixed on the second clamping plate 723.

Referring to fig. 42, fig. 42 is a cross-sectional view of the first light generator 911 of fig. 41. The light generator 91, for example, the first light generator 911, may include a main housing 913 provided with a receiving cavity 9130, a light source 914 mounted within the receiving cavity 9130, a first lens module 915 mounted within the receiving cavity 9130, a functional membrane group 916 mounted within the receiving cavity 9130, and an excitation fiber 917 extending into the receiving cavity 9130. The light source 914 is electrically connected to the control circuit board 40 through a circuit trace for generating excitation light under the control of the control circuit board 40. The excitation light can sequentially pass through the first lens module 915 and the functional film set 916 and then be coupled into the excitation fiber 917.

The main housing 913 may include a front housing 9131 provided with a first sub-housing cavity 9131a and a rear housing 9132 that is snap-fitted with the front housing 9131 and provided with a second sub-housing cavity 9132 a. The first sub-housing chamber 9131a and the second sub-housing chamber 9132a constitute a housing chamber 9130.

The front housing 9131 may include a front housing body 9133 that is snap-fitted to the rear housing 9132, and a front housing cover plate 9134 that covers the front housing body 9133 on a side remote from the rear housing 9132.

The front housing body 9133 may be made of a rigid material such as plastic, metal, etc. The front housing main body 9133 is provided with a first sub-housing chamber 9131a. The front housing body 9133 is provided with a first receiving hole 9131b communicating with the first sub-receiving cavity 9131a at a side away from the rear housing 9132 to yield the light source 914.

The front housing cover 9134 may be made of a rigid material such as plastic, metal, etc. The front housing cover 9134 may be fastened to the front housing main body 9133, for example, by welding, fastening, plugging, screwing, or the like. The front housing cover 9134 may have a circuit trace electrically connected to the light source 914 and a first electrical interface 9141 electrically connected to the circuit trace. The first electrical interface 9141 may be disposed on a side of the front housing cover 9134 that is snapped with the front housing cover 9134. The first electrical interface 9141 may be electrically connected with the control circuit board 40.

The rear housing 9132 may include a rear housing body 9135 that is snap-fit with a front housing 9131, such as a front housing body 9133, and a rear housing cover plate 9136 that covers a side of the rear housing body 9135 that is remote from the front housing 9131, such as the front housing body 9133.

The rear housing body 9135 may be made of a rigid material such as plastic, metal, or the like. The rear housing body 9135 is provided with a second sub-receiving cavity 9132a. The rear housing body 9135 may be fixedly connected to the front housing 9131, e.g., the front housing body 9133, by plugging, snapping, screwing, welding, bonding, etc.

The rear housing cover 9136 may be made of a rigid material such as plastic, metal, etc. The rear housing cover plate 9136 is provided with a second receiving hole 9136a communicating with the second sub-receiving cavity 9132a for mounting the excitation optical fiber 917.

The light source 914 may be an LED lamp. The LED lamp can be a blue LED lamp with the peak wavelength of 470 nm. Of course, other types of light sources are also possible. The light source 914 may be electrically connected with circuit traces on the front housing cover 9134 to make electrical connection with the control circuit board 40. The light source 914 is disposed on a side of the front housing cover 9134 adjacent to the front housing main body 9133. The light source 914 is disposed opposite to the first receiving hole 9131 b. In an embodiment, the light source 914 may extend into the first accommodating hole 9131b, and may also extend from the first accommodating hole 9131b into the first sub-accommodating cavity 9131 a.

The first lens module 915 is mounted in the first sub-housing chamber 9131 a. The optical axis may be the same as that of the light source 914, so that the excitation light emitted by the light source 914 is transmitted, so that the excitation light is reduced in beam and focal length, and the excitation light is better coupled into the excitation fiber 917. The first lens module 915 may include a first lens 9151, a second lens 9152 having the same optical axis as the first lens 9151, and a first clamping ring 9153 for fixing the first lens 9151 and the second lens 9152. The optical axis of the first lens 9151 is the same as that of the light source 914. The optical axis of the first lens 9151 or the optical axis of the second lens 9152 may be referred to as the optical axis of the first lens module 915.

In an embodiment, the lenses, e.g., first lens 9151 and second lens 9152, are both positive lenses, having a positive focal length. The lenses, such as the first lens 9151 and the second lens 9152, may be specifically plano-convex lenses. The plano-convex lens is mainly used for expanding beams, imaging, beam collimation, focusing collimation, beam collimation point light sources and the like in an optical system. One of the incidence plane and the emergence plane of the plano-convex lens is a convex plane, and the other is a plane.

The incident surface of the first lens 9151 is a plane, and the exit surface is a convex surface. The incident surface of the second lens 9152 is convex, and the exit surface is planar. The incident surface of the first lens 9151 is disposed opposite to the light source 914. The incident surface of the second lens 9152 is disposed opposite to the exit surface of the first lens 9151. The exit surface of the second lens 9152 is disposed opposite to the functional membrane set 916.

The first fastening ring 9153 may be sleeved around the first lens 9151 and the second lens 9152 to fix the first lens 9151 and the second lens 9152. When the first lens module 915 is disposed in the first sub-receiving cavity 9131a, the side of the first fastening ring 9153 facing the light source 914 is abutted against the front housing 9131, such as the front housing main body 9133, and the side of the first fastening ring 9153 facing away from the light source 914 is abutted against the rear housing 9132, such as the rear housing main body 9135, so as to fix the front housing 9131 and the rear housing 9132 to the first lens module 915.

It is appreciated that in some embodiments, the first lens module 915 may further include other types of lenses, such as convex lenses, concave lenses, etc., which will not be described in detail. The arrangement of the first lens 9151 and the second lens 9152 in the first lens module 915 is not limited to the above, but may be other arrangements, for example, the first lens 9151 and the second lens 9152 may be directly fixed to the front housing 9131, for example, the front housing main body 9133, by bonding, plugging, fastening, screwing, or the like.

The functional film set 916 is used for performing stray light filtering, excitation light adjustment, and other functions on the excitation light. The functional membrane group 916 may include an optical filter 9161, an optical homogenizing sheet 9162 and a second fastening ring 9163 disposed in the second sub-housing cavity 9132 a.

The filter 9161 is configured to receive the excitation light transmitted through the first lens module 915, for example, the second lens 9152, so as to filter stray light in the excitation light. The filter 9161 is also called a fluorescence filter. The fluorescent filter is a key optical element applied to life science instruments and biomedicine, and has the main functions of selecting and separating characteristic wave band spectrums of excitation light and emitted fluorescence of substances in fluorescent inspection analysis systems of biology, medicine and the like, and then observing the characteristic wave band spectrums through a fluorescence microscope. In one embodiment, the filter 9161 may be an excitation filter. The excitation Filter is called a fluorescence excitation Filter (or a fluorescence Filter, excitation Filter), which refers to a Filter through which only light with a wavelength of excitation fluorescence can pass in a fluorescence microscope or a fluorescence imaging system, and of course, laser light (i.e., the light source 914 can emit laser light) is directly used as excitation light.

The side of the filter 9161 away from the first lens module 915 abuts the rear housing 9132, for example, the rear housing main body 9135. One side of the optical filter 9161, which is close to the first lens module 915, for example, the second lens 9152, abuts against the second clamping ring 9163, so as to realize the installation and fixation of the optical filter 9161 and the rear housing 9132. Of course, the filter 9161 may be fixed to the rear housing 9132, for example, the rear housing main body 9135, by other means, such as adhesion, plugging, fastening, or screwing.

In one embodiment, the filter 9161 may be an excitation filter. The filter 9161 may be an excitation filter of EX450-475 (excitation wavelength 450-475 nm).

The light homogenizing sheet 9162 is configured to receive the excitation light transmitted through the filter 9161. The light homogenizing sheet 9162 is also called a light homogenizer, a diffuser or a homogenizer for converting excitation light into a uniform spot of arbitrary shape.

The light-equalizing sheet 9162 is used for receiving the excitation light transmitted through the filter 9161. One side of the light-homogenizing sheet 9162, which is close to the optical filter 9161, is abutted against the optical filter 9161, and one side of the light-homogenizing sheet 9162, which is far away from the optical filter 9161, is abutted against the rear housing 9132, for example, the rear housing cover plate 9136, so as to fix the light-homogenizing sheet 9162. Of course, the light-equalizing sheet 9162 may be fixed to the rear housing 9132 by other manners, such as adhesion, plugging, fastening, screwing, etc.

One end of the excitation fiber 917 may extend into the rear housing 9132, e.g., the second receiving hole 9136a, so that excitation light transmitted through the light homogenizing sheet 9162 is coupled into the excitation fiber 917. Of course, the excitation fiber 917 may also extend into the rear housing 9132, such as the second sub-housing 9132 a.

The other end of the excitation fiber 917 may be coupled to at least one excitation fiber 8226, so that the plurality of light detection elements 821 can detect with the same excitation light, and detection errors caused by different excitation lights can be reduced. In one embodiment, the number of light detecting elements 821 is 6, and the excitation fiber 917 of the first light generator 911 may be coupled to the excitation fibers 8226 of the three light detecting elements 821. The excitation fibers 917 of the second light generator 912 may be coupled to the excitation fibers 8226 of the three light detectors 821.

In one embodiment, the excitation fiber 917 has a diameter of about 2.5mm. Specifically, the diameter may be 2.5mm.

Referring to fig. 43, fig. 43 is an exploded view of the light receiving assembly 92 of fig. 33. The light receiving assembly 92 may include a light receiving member 921 electrically connected with the control circuit board 40, a light path assembly 922 for light path connection with the detection chamber assembly 82, a first washer 923 disposed on the light receiving member 921 and for fixing the light path assembly 922, a second washer 924 disposed on the first washer 923 and for fixing the light path assembly 922, and a chucking assembly 925 disposed on the second washer 924 and for fixing the light path assembly 922. Wherein the fluorescent light is transmitted to the light receiving member 921 through the light path member 922. The light receiving unit 921 generates a detection signal, and transmits the detection signal to the control circuit board 40.

Referring to fig. 44, fig. 44 is a schematic diagram of the light receiving member 921 in fig. 33. The light receiving member 921 may include a fixed plate 9211 in a ring shape and arranged with circuit wirings, a second electrical interface 9212 provided at the fixed plate 9211 and electrically connected to the circuit wirings, and light sensors 9213 circumferentially uniformly distributed on the fixed plate 9211 and electrically connected to the circuit wirings. Wherein the light receiving member 921 can be used to receive fluorescence. The light receiving member 921 is electrically connected to the control circuit board 40 through the second electrical interface 9212 to transmit a detection signal generated by fluorescence triggering to the control circuit board 40.

The fixing plate 9211 may be installed at the isolation groove 713 and the fixing portion 714 on the support frame 70, for example, the base body 711. The fixing plate 9211 may be disposed at a distance from the base body 711 at the isolation groove 713. Of course, the fixing plate 9211 may also extend into the isolation groove 713 to form a fastening structure with the base body 711. The fixing plate 9211 may be connected and fixed to the base body 711 at the fixing portion 714 by screwing, fastening, plugging, bonding, welding, or the like. The fixing plate 9211 may surround the fixing groove 712. In an embodiment, the fixing plate 9211 may be similar in size and even identical in size to the support base 80, such as the support base body 81, so that the support base 80, such as the receiving fiber channel 8227 of the detection cavity assembly 82, is located above the light sensor 9213, even directly above the light sensor 9213, thereby reducing the difficulty in arranging the receiving fiber 8228.

In one embodiment, the light sensor 9213 is a photodiode.

Referring to fig. 43, the optical path assembly 922 may include at least one sub-optical path assembly 9221. In an embodiment, the number of sub-optical path components 9221 may be identical to the number of light sensors 9213 in the light receiving member 921 such that the sub-optical path components 9221 correspond to the light sensors 9213 one by one.

Referring to fig. 45 and 46, fig. 45 is a schematic structural diagram of the neutron optical path assembly 9221 in fig. 43. FIG. 46 is a cross-sectional view of the neutron optical path assembly of FIG. 45. The sub-optical path assembly 9221 may include a second lens module 9222 that transmits fluorescent light to the light sensor 9213 and a receiving fiber 9223 that transmits fluorescent light to the second lens module 9222.

The second lens module 9222 may include a third lens 9224 mounted in the first gasket 923, a third clamping ring 9225 for fixing the third lens 9224 in the first gasket 923, a fourth clamping ring 9226 mounted in the second gasket 924, and a fourth lens 9227 fixed in the second gasket 924 by the fourth clamping ring 9226.

It will be appreciated that the designations "first lens", "second lens", "third lens", "fourth lens", and "lens" etc. may be interchangeable in some embodiments. For example, in one embodiment, the "first lens" in other embodiments is referred to as the "second lens", and correspondingly, the "second lens" in other embodiments is referred to as the "first lens".

In an embodiment, the lenses, e.g., third lens 9224 and fourth lens 9227, are both positive lenses, having a positive focal length. The lenses such as the third lens 9224 and the fourth lens 9227 may be specifically plano-convex lenses. The plano-convex lens is mainly used for expanding beams, imaging, beam collimation, focusing collimation, beam collimation point light sources and the like in an optical system. One of the incidence plane and the emergence plane of the plano-convex lens is a convex plane, and the other is a plane.

The incident surface of the third lens 9224 is convex, and the exit surface is planar. The incident surface of the fourth lens 9227 is a plane, and the exit surface is a convex surface. The incident surface of the third lens 9224 is disposed opposite to the exit surface of the fourth lens 9227. The exit surface of the third lens 9224 is disposed opposite to the photosensor 9213. The incident surface of the fourth lens 9227 is disposed opposite to the receiving fiber 9223.

In an embodiment, an Emission Filter (Emission Filter ) may also be disposed between the third lens 9224 and the fourth lens 9227. The emission filter is a filter for selecting and transmitting fluorescence emitted from a substance to be detected, and the wavelength of the emitted light is generally longer than that of the excitation light when the substance to be detected is in a cut-off state, and a narrow band filter, a band-pass filter, or a long-wave pass filter may be selected as the emission filter.

In one embodiment, the emission filter may be specifically an excitation filter of EM522-645 (emission wavelengths 522-645 nm).

The third clamping ring 9225 is disposed on the incident surface side of the third lens 9224, so as to press the third lens 9224 against the first gasket 923, thereby fixing the third lens 9224.

The fourth fastening ring 9226 is disposed on the exit surface side of the fourth lens 9227, so as to press the fourth lens 9227 against the second gasket 924, thereby fixing the fourth lens 9227.

It will be appreciated that the designations "first snap ring", "second snap ring", "third snap ring", "fourth snap ring", and "snap ring" may be interchangeable in some embodiments. For example, in one embodiment, the "first clamping ring" in other embodiments is referred to as the "second clamping ring", and correspondingly, the "second clamping ring" in other embodiments is referred to as the "first clamping ring".

It is understood that in some embodiments, the second lens module 9222 may further include other types of lenses, such as convex lenses, concave lenses, and other functional films, such as light homogenizing films, optical filters, and the like, which will not be described in detail. The arrangement of the third lens 9224 and the fourth lens 9227 is not limited to the above, and other arrangements are also possible, for example, the third lens 9224 may be directly fixed to the first gasket 923 by bonding, plugging, fastening, screwing, or the like. For example, the fourth lens 9227 may be directly secured to the second gasket 924 by adhesive, plugging, snapping, screwing, or the like.

In one embodiment, the second lens module 9222 provides an emission filter between the third lens 9224 and the fourth lens 9227. The emission filter is a filter for selecting and transmitting fluorescence emitted from a substance to be detected, and the wavelength of emitted light is generally longer than that of excitation light, except for autofluorescence of the substance to be detected, and a band filter, a band-pass filter, a long-wave pass filter, or the like may be selected as the emission filter.

In an embodiment, an emission filter may be placed between the first gasket 923 and the second gasket 924 to achieve a fixed connection to the emission filter.

The receiving fiber 9223 may include a receiving fiber body 9223a and a receiving fiber nipple 9223b disposed at an end of the receiving fiber body 9223 a. Wherein the receiving fiber optic connector 9223b is disposed within the first gasket 923 and/or the second gasket 924 to transmit fluorescent light to the second lens module 9222, e.g., the fourth lens 9227. The junction of receiving fiber body 9223a and receiving fiber nipple 9223b forms a securing location for mating with clamping assembly 925. In one embodiment, the diameter of the receiving fiber 9223, e.g., receiving fiber body 9223a, is about 2.5mm. Specifically, the diameter may be 2.5mm.

One end of the receiving optical fiber 9223 may be connected to one receiving optical fiber 8228 such that fluorescence is transmitted to the light sensor 9213 through the receiving optical fiber 8228 and the receiving optical fiber 9223.

Referring to fig. 47, fig. 47 is a schematic structural view of the first gasket 923 in fig. 43. The first gasket 923 may be made of a rigid material such as metal, plastic, or the like. The first gasket 923 may have a ring-shaped structure, and in particular, may conform to the shape of the fixing plate 9211, such that the first gasket 923 is laminated with the fixing plate 9211.

The first washer 923 may be fastened to the fixing plate 9211 by screwing, welding, fastening, bonding, or the like.

The first gasket 923 is provided with a yielding notch 9231 to yield the light receiving member 921, such as the second electrical interface 9212. When the first gasket 923 and the fixing plate 9211 are stacked, the second electrical interface 9212 may be disposed in the yielding notch 9231.

The first gasket 923 has a plurality of first filling holes 9232 circumferentially distributed therein for mounting the second lens module 9222 such as the third lens 9224 and the third clamping ring 9225. The side of the third lens 9224 facing the light sensor 9213 may abut the first gasket 923. The side of the third lens 9224 away from the optical sensor 9213 may abut against the third clamping ring 9225, so as to realize the fixed connection between the third clamping ring 9225 and the first washer 923 and the third lens 9224.

The first filling hole 9232 may be disposed opposite the light sensor 9213 so that the light sensor 9213 may receive fluorescence. In one embodiment, the light sensor 9213 may extend into the first fill hole 9232. The exit surface of the third lens 9224 may abut the first gasket 923. The third clamping ring 9225 may be fixedly connected to the first washer 923 to achieve connection fixation of the third lens 9224.

Referring to fig. 48, fig. 48 is a schematic diagram illustrating a structure of the second gasket 924 in fig. 43. The second washer 924 may be made of a rigid material such as metal, plastic, etc. The second gasket 924 may have an annular structure, and may specifically conform to the shape of the first gasket 923, such that the first gasket 923 is stacked with the second gasket 924. The second gasket 924 is provided with a yielding notch 9241 opposite to the yielding notch 9231 to yield the second electrical interface 9212. When the second gasket 924, the first gasket 923, and the fixing plate 9211 are stacked, the second electrical interface 9212 may be disposed in the yielding notch 9231 and the yielding notch 9241.

The first gasket 923 may be secured to the second gasket 924 by screwing, welding, snapping, bonding, or the like. In one embodiment, the first gasket 923 may be integrally formed with the second gasket 924.

The second gasket 924 is provided with a plurality of second filling holes 9242 circumferentially distributed for mounting the second lens module 9222 such as the fourth lens 9227 and the fourth clamping ring 9226. The second filling hole 9242 may be disposed opposite to the first filling hole 9232 so that the light sensor 9213 may receive fluorescence. The side of the fourth lens 9227 facing the photosensor 9213 may abut against the fourth clamping ring 9226. The side of the fourth lens 9227 away from the photosensor 9213 may abut against the second gasket 924, so as to realize the fixed connection of the fourth clamping ring 9226 and the second gasket 924 to the fourth lens 9227 in a matched manner. The receiving fiber optic connector 9223b of the receiving fiber optic 9223 may extend into the second filling hole 9242 away from the second gasket 924.

It will be appreciated that the first gasket 923 and the second gasket 924 may form an assembly housing, while the first fill hole 9232 and the second fill hole 9242 communicate to form a fill hole.

Referring to fig. 43, a clamping assembly 925 is disposed on a side of the second washer 924 remote from the first washer 923 for fixedly receiving the optical fibers 9223. The clamping assembly 925 may include a plurality of circumferentially spaced second clamping tabs 9251. Referring to fig. 49, fig. 49 is a schematic structural view of the second clamping piece 9251 in fig. 43. The second clip 9251 may be made of a rigid material such as plastic, metal, or the like. The second chucking plate 9251 may include a chucking body 9252. The chucking body 9252 may have a strip-shaped sheet structure so as to be disposed on the second gasket 924. The chucking body 9252 has a plurality of chucking holes 9253 arranged in an extending direction thereof. The chucking holes 9253 are provided extending inward from the edges. Between two adjacent clamping holes 9253 are clamping teeth 9254. The receiving fiber optic connector 9223b may be captured within the second filling hole 9242 by the latch 9254 by attaching the clamping body 9252 to a side of the second washer 924 remote from the first washer 923 such that the receiving fiber optic body 9223a is located between two adjacent latches 9254. A fixed connection between the receiving fiber 9223 and the second washer 924 is achieved.

It will be appreciated that the designations "first clip", "second clip" and "clip" may be interchangeable in some embodiments. For example, in one embodiment, the "first grip tab" in other embodiments is referred to as the "second grip tab", and correspondingly, the "second grip tab" in other embodiments is referred to as the "first grip tab".

The chucking body 9252 is provided with a fixing portion 9255 so as to achieve a fixed connection between the chucking body 9252 and the second washer 924. In an embodiment, the fixing portion 9255 may be perforated so as to pass through the fixing portion 9255 by a screw and bolt or the like, pass through the second washer 924, the first washer 923, and be screwed to the light receiving member 921 such as the fixing plate 9211.

It is understood that the clamping body 9252 may be connected and fixed to the second washer 924 by other manners, such as plugging, buckling, etc., which will not be described herein.

In one embodiment, all of the second clamping tabs 9251 in the clamping assembly 925 are of unitary construction.

Control circuit board 40

Referring again to fig. 1 and 2, the control circuit board 40 may include a first sub-control circuit board 41 fixed to the chassis 10, e.g., the circuit mounting board 13, and a second sub-control circuit board 42 disposed on top of the chassis 10, e.g., the top board 111. Wherein the first sub-control circuit board 41 is electrically connected with the second sub-control circuit board 42.

The first sub-control circuit board 41 may be mounted on the connection posts 1312 of the circuit mounting board 13 in the rack 10 to avoid the first sub-control circuit board 41 directly on the mounting board body 131. Of course, in an embodiment, when the connection post 1312 is omitted, the first sub-control circuit board 41 may be directly fixed to the mounting board body 131.

The first sub-control circuit board 41 may be electrically connected to the housing 10, such as the first driver 1212, for controlling the sliding position of the test card holder 20 relative to the housing 10.

The first sub-control circuit board 41 may be electrically connected to the pressing board 50, for example, the first circuit board 55, so as to control the electromagnetic member 52, magnetically apply force to the pressing member 53, so as to control the heating assembly 54, and heat the detection card.

The first sub-control circuit board 41 may be electrically connected to the shipping assembly 60, such as the second drive 6141, to control the third drive 64 and the card holder 65 to slide with respect to the carriage 61.

The first sub-control circuit board 41 may be electrically connected to the shipping assembly 60, for example, the third driving member 64, so as to control the third driving member 64 to drive the card holder 65 to perform centrifugation on the test card.

The first sub-control circuit board 41 may be electrically connected to a test cavity assembly 82, such as a heat generating device, to control the test socket 822 to heat the test card.

The first sub-control circuit board 41 may be electrically connected to the loading chamber assembly 83, e.g., a heating device, to control the loading chamber mount 833 to heat the test card.

The first sub-control circuit board 41 may be electrically connected to the detection assembly 90, for example, the light source 914, so as to control the light source 914 to emit excitation light.

The first sub-control circuit board 41 may be electrically connected to a detection assembly 90, such as a light sensor 9213, to control the light sensor 9213 to receive fluorescent light.

The first sub-control circuit board 41 may be electrically connected to the rack 10, for example, the first limit switch 15, and the detection card conveying seat 20, for example, the optical sensor 616, so as to control the position of the third driving member 64 in the carrying member 62 to drive the card holder 65 to slide.

The first sub-control circuit board 41 may be electrically connected with the rack 10, for example, the first sub-limit switch 162, the second sub-limit switch 163, so as to control the sliding position of the shipping assembly 60.

The first sub-control circuit board 41 may be electrically connected with the carrying member 62 such as the positioning light generator 615, the support frame 70 such as the positioning light receiver 716 to control the position of the detection card.

The second sub-control circuit board 42 may be mounted above the rack 10, such as the top plate 111. In an embodiment, when the molecular diagnostic apparatus 100 is provided with a cabinet, the second sub-control circuit board 42 may be provided at a position where the cabinet is opposite to the top plate 111.

The second sub control circuit board 42 may be electrically connected to an output device such as a display, a printer, etc., to output diagnostic data of the molecular diagnostic device 100 through the output device.

The second sub-control circuit board 42 may be electrically connected to an input device such as a display, a keyboard, and the code scanning device 14, so as to input a control instruction to the molecular diagnostic device 100, for example, the control circuit board 40 through the input device, so that the molecular diagnostic device 100 controls the detection card conveying seat 20 and/or the detection card detecting seat 30 through the control circuit board 40.

In an embodiment, one of the second sub-control circuit board 42 and the first sub-control circuit board 41 may be omitted, and the two are integrated on one sub-control circuit board.

Detection card 93

Next, a test card is described which can be used in the molecular diagnostic device 100 of the above embodiment to perform the test of the sample loaded on the test card and further process it to form diagnostic data.

Referring to fig. 50, fig. 50 is a schematic structural diagram of a test card according to an embodiment of the application. The test card 93 is also referred to as a molecular diagnostic centrifugation test card or test card. The detection card 93 may include a body 94 provided with a sample loading chamber, a flow channel, a waste liquid chamber, an isolation chamber and a detection chamber, an isolation layer 95 covering one side of the body 94, and a cover 96 covering the sample loading chamber of the body 94.

Referring to fig. 50, 51 and 52 together, fig. 51 is a cross-sectional view of the test card 93 of fig. 50 along the line L-L, and fig. 52 is a schematic perspective view of the test card 93 of fig. 50. The body 94 is made of a rigid material such as plastic or the like. The specific body 94 may be made of ABS (Acrylonitrile Butadiene Styrene plastic, acrylonitrile-butadiene-styrene), PDMS (Polydimethylsiloxane), PC (Polycarbonate), PMMA (Polymethyl methacrylate ), PS (General purpose polystyrene, polystyrene), PP (Polypropylene), COC (copolymers of cycloolefin, cyclic olefin copolymer), COP (Cyclo Olefin Polymer, cyclic olefin polymer), or the like, and is manufactured by injection molding, numerical control machine processing, or 3D printing.

The body 94 may be generally plate-like in configuration. The fan-shaped structure is generally fan-shaped, and can be in a fan ring shape, a fan leaf shape or a cake shape. For example, body 94 is a fan formed by two straight sides and an arcuate side joined end to end. For example, the body 94 is a fan ring formed by sequentially connecting a straight line edge, an outer circular arc edge, a straight line edge, and an inner circular arc edge end to end. Of course, the body 94 may have other shapes, which will not be described in detail.

In one embodiment, the angle between the two straight sides of the fan-shaped structure of body 94 may be 40 ° -60 °, the diameter of the inner circular arc may be 10mm-100mm, and the diameter of the outer circular arc may be 100mm-200mm. By adopting the detection cards 93 with the size structure, at least 6 detection cards can be arranged in the detection plane of the molecular diagnosis equipment 100 to form a circular surface, so that at least 6 detection cards 93 can be detected simultaneously, the overall detection efficiency is improved, and the detection requirements of a large scale can be met.

The body 94 is provided with a mounting portion 941 protruding toward a side away from the isolation layer 95 near the center of the outer arc or the inner arc. The body 94 is provided with a sample addition chamber 9411 recessed at a position opposite to the mounting portion 941 on a side close to the separation layer 95 for sample addition at the sample addition chamber 9411. The sample application chamber 9411 is mainly used for pretreatment of a sample (liquid sample), and the pretreatment may include one or more of chemical treatment, heat treatment, enzyme treatment, physical separation, and the like. In some embodiments, the loading chamber 9411 has a volume of approximately 200-2000. Mu.L. The sample addition chamber 9411 may be preloaded with a dry reagent, which may be air dried/dried in situ, or may be added as a lyophilized reagent to the sample addition chamber 9411.

The body 94 is provided with a fourth fastening portion 942 at a location remote from the side of the barrier layer 95 and near the outer circular arc edge to mate with the shipping assembly 60, such as the second fastening portion 654. In an embodiment, the fourth fastening portion 942 may be a protrusion. It will be appreciated that the second fastening portion 654 may be interchanged with the fourth fastening portion 942, and that the second fastening portion 654 and the fourth fastening portion 942 may be fastened in other manners.

It will be appreciated that the designations "first trim portion", "second trim portion", "third trim portion", "fourth trim portion", and "trim portion" may be interchangeable in some embodiments. For example, in one embodiment, the "first fastening portion" in other embodiments is referred to as a "second fastening portion", and correspondingly, the "second fastening portion" in other embodiments is referred to as a "first fastening portion".

The body 94 is provided with a first limit portion 943 bent at the edge portion of one straight line side close to the outer arc side and away from the isolation layer 95, and a second limit portion 944 protruding at the portion of the other straight line side close to the outer arc side and away from the isolation layer 95. The first limit portion 943 and the second limit portion 944 of the body 94 cooperate to fix the detection card 93 so as to smoothly perform centrifugal processing of the detection card 93, and the body 94 is provided with a waste liquid chamber 9441 in a recess at a position opposite to the second limit portion 944 on a side close to the separation layer 95. The body 94 is provided with a plurality of plug-in connection part groups uniformly distributed along the extending direction of the outer arc edge between the first limit part 943 and the second limit part 944 at one side far away from the isolation layer 95. Each set of prongs may include a first prong 945 and a second prong 946. The connecting line between the first inserting portion 945 and the second inserting portion 946 can pass through the center of the outer arc edge. The first mating portion 945 is disposed between the mounting portion 941 and the second mating portion 946. The first mating portion 945 and the second mating portion 946 may be configured to mate with the test card holder 30, such as the isolation slot 8224 and the test slot 8223.

The body 94 is provided with an isolation chamber 9451 recessed at a position opposite to the first plugging portion 945 on a side close to the isolation layer 95. The isolation chamber 9451 is provided with a meltable isolator. The separator is switchable between a molten state and an unmelted (typically solid) state. When the detection card 93 is not used for detection, the separator may be controlled to be in an unmelted state, at which time the separator may prevent the sample from entering the detection chamber 9461 (shown in fig. 52) through the flow path. In some embodiments, the separator may be paraffin wax, microcrystalline wax, synthetic wax, or natural wax.

The body 94 is provided with a detection chamber 9461 recessed at a position adjacent to one side of the separation layer 95 and opposite to the second insertion portion 946. The detection chamber 9461 is provided with a reagent. Isolation chamber 9451 communicates with detection chamber 9461 on a side near isolation layer 95. The spacer within the spacer chamber 9451 may also be used to seal the spacer reagent to prevent reverse entry of the reagent into the spacer chamber 9451. The reagent is maintained within the detection chamber 9461. While the test is being performed, the separator may be controlled to be in a molten state, at which time the sample may enter the detection chamber 9461 through the sample addition chamber 9411 to react with the reagent in the detection chamber 9461 to complete the test.

Reagents and meltable spacers may be layered within the detection chamber 9461. In some embodiments, the separator may be paraffin wax, microcrystalline wax, synthetic wax, or natural wax. The separator is solid at normal temperature and low temperature, becomes liquid after being heated to a specific temperature, and has no inhibition effect on nucleic acid amplification reaction. In some embodiments, the reagents may be dry reagents including primers for the amplification reaction and one or more of DNA (deoxyribonucleic acid ) binding dyes, enzymes, magnesium sulfate, potassium chloride, dNTPs (Nucleoside triphosphate, deoxynucleoside triphosphates). The dry reagent is filled into the detection chamber 9461 in a liquid state, and is formed by a drying process, the temperature of which is less than the melting temperature of the separator, and the drying process includes air drying, and freeze-drying. In the detection heating process, the reagent and the separator are both in liquid state, and the separator is replaced by the detection cavity 9461 under the action of the centrifugal field due to the fact that the specific gravity of the separator is smaller than that of the reagent, so that the reaction and detection are not affected.

In some embodiments, the spacer is loaded into the detection chamber 9461 in a molten state and formed by natural solidification or reduced temperature solidification. When the test is not performed, the separator can be controlled to be in an unmelted state, and the sealed and isolated storage of the reagent can be realized through the separator. When the test is required, the separator is controlled to be in a melted state, for example, by heating the test card 93, so that the separator is melted by heating, at this time, the separator can move out of the test cavity 9461 and flow into the separation cavity 9451 under the action of centrifugal force, and the sample can enter the test cavity 9461, and then the separator is solidified again to seal the mouth of the test cavity 9461, so that a mutual separation seal is formed for the plurality of test cavities 9461, so that the reaction or the test can be performed independently between the test cavities 9461.

The body 94 is provided with a flow channel 947 on a side close to the isolation layer 95 to communicate the sample addition chamber 9411 with the isolation chamber 9451.

The body 94 is provided with an abutment groove 948 at a position opposite to the flow passage 947 on a side away from the separation layer 95 so as to be engaged with the abutment portion 8336. For example, the abutting portion 8336 can be placed in the abutting groove 948 to heat the portion of the flow channel 947, so as to avoid condensation of water vapor in the flow channel 947, further reduce influence on subsequent detection process, and improve detection accuracy. In some embodiments, the abutment slot 948 may be omitted.

The isolation layer 95 may be a film-like structure, but other structures are also possible. The isolation layer 95 may be made of a material such as a compacting adhesive, an ultraviolet curing adhesive or an optical grade double sided adhesive, or may be made of a material similar to the main body 94. The isolation layer 95 may be attached to the body 94, and may be specifically sealed and fixed by, for example, ultrasonic welding, laser welding, adhesive sealing, etc., so as to isolate the flow channel 947, the waste liquid chamber 9441, the isolation chamber 9451, and the detection chamber 9461.

The lid 96 is provided to cover the mouth of the sample chamber 9411. To seal off the loading chamber 9411. When sample addition is desired, the cover 96 can be opened, sample can be added to the sample addition chamber 9411, and the cover 96 can be closed. The cover 96 can block water and ventilate, so that water vapor generated in the heating process can be discharged, and the air pressure in the test card 93 is reduced, so that a good ventilation effect can be ensured, and escape of pollutants such as aerosol and biomolecules generated in the amplification reaction can be blocked, so that pollution to personnel and environment caused by detection is avoided.

When the detection card 93 centrifugally rotates, the sample liquid passes through the sample application chamber 9411 and the flow channel 947. The separator is in a solid state at this time, so that the detection chamber 9461 can be sealed, and the sample liquid cannot flow to the detection chamber 9461. After the sample liquid is heated, the separator is melted by heat and flows to the detection chamber 9461, so that the flow channel 947 and the detection chamber 9461 can be communicated, and the sample liquid can flow into the detection chamber 9461. Because the specific gravity of the isolator is smaller than that of the reagent, the isolator can be replaced on the reagent under the action of the centrifugal field, the reaction and detection are not affected, and the detection cavity 9461 can be sealed.

Some embodiments of the present application further provide a method for detecting based on the detection card 93. The method can be used in the molecular diagnostic apparatus 100 in the above embodiment. Referring to fig. 53, fig. 53 is a schematic diagram illustrating a usage process of the test card in fig. 50. The specific steps are as follows:

step S5301: the sample application chamber receives a sample.

After the sample is added to the sample-adding chamber 9411, the sample needs to be subjected to a heating pretreatment, and the heating mode may be a metal heating block, a heating air flow, electromagnetic waves (infrared radiation, laser, microwave) or the like. The heating area of the detection card can be the area near the sample loading cavity. The heating process is to raise the temperature to a specified temperature, such as 90 ℃. And after reaching the specified temperature, preserving heat for 3-10min according to the specified requirement to realize pretreatment. After the pretreatment is completed, the temperature of the sample liquid is reduced to a specified temperature, such as 60 ℃.

Step S5302: the test card is rotated by centrifugal force to cause the sample to flow through the flow channel to the test chamber.

And (5) performing centrifugal treatment on the rotation control of the detection card. For example, the rotation direction can be controlled to be clockwise, the rotation speed is more than 1000rpm, and the rotation time is about 10-15s. Through the rotation, the sample liquid can flow from the sample adding cavity to the detection cavity through the flow channel, so that the filling of the sample in the detection cavity can be realized conveniently. And excess sample liquid will enter the waste chamber.

Step S5303: the melting spacer is heated so that the sample flows into the detection chamber and mixes with the reagents in the detection chamber.

Here, it is necessary to heat treat the region near the detection chamber so that the temperature is higher than the melting point of the separator, thereby melting the separator and mixing the sample with the reagent in the detection chamber.

Step S5304: the centrifuge rotates to displace the spacer with the sample in the detection chamber and seal the inlet end of the detection chamber.

The rotation control is performed again on the detection card. Wherein, the motor can rotate clockwise, the rotation speed is more than 1000rpm, and the rotation time is 10-15s. At this time, due to the rotation of the detection card, the sample enters the detection cavity, the isolator and the aqueous solution in the detection cavity are replaced, and the isolator is transferred to the inlet end of the detection cavity, so that the sealing of each detection cavity is completed. And then changing the motor control parameters to enable the detection card to alternately rotate clockwise and anticlockwise. For example, the test card may be controlled to rotate clockwise at a speed of 3000rpm for 1s, then counter-clockwise at a speed of 3000rpm for 1s, and alternately 10-15 times. The sample in the detection cavity and the reagent can be completely dissolved and mixed by the mode of clockwise and anticlockwise alternating rotation.

Meanwhile, the separator flows to the inlet end of the detection cavity under the action of centrifugal force after being heated and melted, so that the inlet end of the detection cavity is sealed.

Step S5305: the mixed mixture was tested.

In this step, amplification reactions and detection are required. If real-time detection is used, the detection and amplification reaction are performed simultaneously, and if end-point detection is used, the detection is performed after the amplification is completed. Wherein the amplification reaction can be achieved by: heating the vicinity of the detection cavity, and controlling the temperature within the range of 60-75 ℃. After reaching the specified temperature, the amplification reaction is completed by preserving the heat for 30-60min according to the specified requirement.

Next, a procedure for performing a sample test using the molecular diagnostic device 100 and the test card 93 will be described, with the following specific procedures:

the control circuit board 40 performs basic information setting such as the number of samples, the type, the heating temperature, the number of rotations, the operation parameters, etc. by the detection card 93 through the input device. After the basic information is set, the detection of the detection card 93 may be further turned on by the input device.

A test card 93 loaded with a sample.

Under the control of the control circuit board 40, the first driving element 1212 respectively controls the first lead screw 1221 and the second lead screw 1222 to rotate through the synchronization assembly 1213, so that the pressing plate 50 drives the delivery assembly 60 to slide on the first guide rail 1126 toward the top plate 111. When the limit plate 5813 triggers the second limit switch 16, for example, the second sub-limit switch 163, the pressing plate 50 reaches a predetermined position. The first driver 1212 stops operating after the control circuit board 40 receives the signal from the second limit switch 163.

Under the control of the control circuit board 40, the second driving member 6141 slides the carrying member 62 along the second guide rail 613 to a side away from the first connecting plate 6111 via the lead screw 6142. When the first limit switch 15 is triggered by the shipper 62, e.g., the second limit, the shipper 62 reaches a predetermined position. The second driving member 6141 stops operating after the control circuit board 40 receives the signal that the first limit switch 15 is triggered.

The test card 93 loaded with sample is placed at a recess 653 of the shipper 62, such as the receptacle 65. The detection card 93, for example, the mounting portion 941 is placed in the receiving hole 655. The test card 93 is fastened to the second fastening portion 654 of the card holder 65, for example, by the fourth fastening portion 942, thereby completing placement of one test card 93.

The control circuit board 40 scans the image of the information mark on the card holder 65 through the code scanning device 14, judges whether the information mark is the detection card 93 predetermined by the user, and if not, carries out early warning prompt. If yes, the next step is carried out.

Under the control of the control circuit board 40, the third driving member 64 starts to rotate, and drives the card holder 65 to rotate, so that the recess 653 of the next detection card 93 reaches a predetermined position, and then the placement of the next detection card 93 is operated.

After the detecting card 93 is placed in the concave portion 653 on the card holder 65, the detecting card 93 is circumferentially and uniformly distributed on the card holder 65. If the number of test cards 93 is insufficient to be circumferentially distributed on the card holder 65, trim cards may be placed in the recess 653 of the card holder 65 so that the trim cards are circumferentially distributed on the card holder 65 along with the test cards 93. The test card 93 is thus placed.

Under the control of the control circuit board 40, the second driving member 6141 slides the carrying member 62 along the second guide rail 613 to the side close to the first connecting plate 6111 via the lead screw 6142. When the shipping member 62, such as the first stop 634, triggers the light sensor 616, the shipping member 62 reaches a predetermined position. The second driving part 6141 stops operation after the control circuit board 40 receives the signal that the light sensor 616 is triggered.

The carriage 61, such as the positioning light generator 615, emits light that is transmitted through the positioning holes 576, 517 to the card holder 65 under the control of the control circuit board 40.

If the light passes through the positioning hole 6522 on the card support 65 again, the light passes through the supporting seat 80, such as the positioning hole 814, and is transmitted to the positioning light receiver 716. The control circuit board 40 will confirm that the test card is in the predetermined position.

If the light cannot pass through the positioning holes 6522 on the card support 65. The positioning light receiver 716 cannot receive the light emitted from the positioning light generator 615. The control circuit board 40 controls the third driving member 64, so that the third driving member 64 drives the card holder 65 to rotate, and the positioning hole 6522 on the card holder 65 is opposite to the positioning hole 576, and the light passes through the positioning holes 576, 517, 6522 and is received by the positioning light receiver 716. And then proceeds to the next step.

Under the control of the control circuit board 40, the first driving element 1212 respectively controls the first lead screw 1221 and the second lead screw 1222 to rotate through the synchronization assembly 1213, so that the pressing plate 50 drives the delivery assembly 60 to slide on the first guide rail 1126 toward the side far from the top plate 111. When the shipper 62, such as the card holder 65, is in quick contact with the support 80, such as the support body 81. The first positioning member 656 of the card support 65 facing the side of the supporting seat main body 81 will extend into the second positioning member 813, and due to the special structure of the first positioning member 656, the first positioning member 656 is easily placed in the second positioning member 813, so as to position the detection card 93.

When the clip 65 abuts against the support base 80, for example, the support base main body 81. The test card 93 will be positioned on the support base 80. The detection card 93, for example, the mounting portion 941, is to be placed in the loading chamber setting groove 8332 of the loading chamber mounting seat 833. The detection card 93, e.g. the first mating portion 945, will be placed in the light detecting member 821, e.g. the isolation groove 8224. The detection card 93, for example, the second socket 946, will be placed in the light detecting member 821, for example, the detection groove 8223. The detection card 93, for example, the first limiting portion 943, is disposed in the supporting base body 81, for example, the extending groove 815, and abuts against the mounting table 816. The detection card 93, for example, the second stopper 944 is placed in the support base body 81, for example, the extension groove 815, and abuts against the mounting table 816. To this end, the placement of the detection card 93 on the support base 80 is completed.

When the limit plate 5813 triggers the second limit switch 16, e.g., the first sub-limit switch 162, the pressing plate 50 reaches a predetermined position. The first driver 1212 ceases operation after the control circuit board 40 receives the signal from the first sub-limit switch 162. At this time, the pressing plate 50, for example, the heating element 54, is placed in contact with the detecting card 93 at a position where the isolation chamber 9451 and the detecting chamber 9461 are provided, and the pressing member 53, for example, the abdication portion 5312 and the sub abdication portion 5313 abdies the cover 96 of the detecting card 93 to clamp the cover 96. At the same time, the securing of the pressing piece 53 is released because the locking piece 56 is pressed.

Under the control of the control circuit board 40, the heating devices in the loading chamber assembly 83, for example, the loading chamber mounting seat 833, and the heating devices in the second heating member 542 are heated to complete the heating of the detection card 93, for example, the loading chamber 9411. The heating pretreatment of the sample is realized.

In the presence of the electromagnetic member 52, the electromagnetic force needs to be canceled under the control of the control circuit board 40 so that the pressing member 53 is placed above the card holder 65. Specifically, the pressing member 53, for example, the first clamping portion 5314 is sleeved on the third clamping portion 6521 of the clamping support 65, so that the pressing member 53 and the clamping support 65 are fixed, and in addition, the clamping support 65 is tightly abutted to the pressing member 53 by matching with the acting force generated by the electromagnet, the permanent magnet and the like in the clamping support 65. Without the hold-down member 53, the holding-down member 53 is fixed only by the electromagnetic member 52.

Under the control of the control circuit board 40, the first driving element 1212 respectively controls the first lead screw 1221 and the second lead screw 1222 to rotate through the synchronization assembly 1213, so that the pressing plate 50 drives the delivery assembly 60 to slide on the first guide rail 1126 towards the side close to the top plate 111. When the limit plate 5813 triggers the second limit switch 16, for example, the second sub-limit switch 163, the pressing plate 50 reaches a predetermined position. The first driver 1212 stops operating after the control circuit board 40 receives the signal from the second limit switch 163.

Under the control of the control circuit board 40, the third driving member 64 starts to rotate to drive the card holder 65 to rotate, so as to realize the first centrifugal treatment of the detection card. After completion, the repositioning of the test card is achieved by the cooperation of the positioning light generator 615 and the positioning light receiver 716.

The detection card 93 is again fed onto the holder 80, for example, the holder body 81, under the control of the control circuit board 40.

The heating device in the first heating element 541 is controlled to be heated under the control of the control circuit board 40, and the heating device in the photodetection element 821 is controlled to be heated. The secondary heating of the detection card 93 is realized.

The test card 93 is then centrifuged again.

Finally, the test card 93 is transferred to the support 80, for example, the support body 81.

Under the control of the control circuit board 40, the light generator 91 emits excitation light, and the mixture in the detection chamber 9461 of the detection card 93 is excited in the detection groove 8223. The light sensor 9213 in the light receiving member 92 receives fluorescence. The detection signal is received by the control circuit board 40 and processed to form diagnostic data.

While the foregoing is directed to the preferred embodiments of the present application, it will be appreciated by those skilled in the art that changes and modifications may be made without departing from the principles of the application, such changes and modifications are also intended to be within the scope of the application.

Claims

1. A molecular diagnostic device, comprising:

2. The molecular diagnostic apparatus according to claim 1, wherein the first heating member is mounted on the cartridge holder, the molecular diagnostic apparatus further comprising:

3. The molecular diagnostic apparatus according to claim 2, wherein the test card test socket comprises:

the supporting seat main body is used for supporting the detection card;

4. A molecular diagnostic device according to claim 3, wherein the support base body is provided with an assembly table on a side supporting the test card, the assembly table being for mounting the test chamber, the test base being mounted on the assembly table.

5. The molecular diagnostic apparatus according to claim 4, wherein the mount is provided with a receiving hole, the mount main body is provided with a recess portion on a side away from the mount, the recess portion communicates with the receiving hole, and the detection mount is located in the recess portion.

6. The molecular diagnostic device according to claim 5, wherein the detection cartridge comprises:

7. The molecular diagnostic device according to any one of claims 4 to 6, wherein the number of the detecting seats is plural, the number of the assembling tables is plural, the plurality of detecting seats is one-to-one corresponding to the plurality of assembling tables, and the plurality of detecting seats are circumferentially arranged.

8. The molecular diagnostic apparatus according to any one of claims 3 to 6, wherein the second heating member is provided on the cartridge detection seat, the molecular diagnostic apparatus further comprising:

9. The molecular diagnostic device of claim 8, wherein the first circuit board is disposed on a side of the cradle body that is remote from the test card.

10. The molecular diagnostic device according to any one of claims 3-6, wherein the cartridge further comprises:

and the supporting frame is used for supporting the supporting seat main body.

11. The molecular diagnostic device according to any one of claims 2-6, wherein the pressure plate comprises:

12. The molecular diagnostic apparatus according to claim 11, wherein the pressure plate body comprises:

13. The molecular diagnostic device according to claim 12, wherein the first housing has a flange at an edge of the side of the clamping hole away from the second housing to be clamped with the third heating member.

14. The molecular diagnostic apparatus according to any one of claims 12 to 13, wherein the number of the clamping holes is plural, the number of the third heating members is plural, the plurality of the clamping holes are in one-to-one correspondence with the plurality of the third heating members, and the plurality of the clamping holes are arranged around the circle.

15. The molecular diagnostic apparatus according to any one of claims 12 to 13, wherein the second heating member is provided on a side of the first housing away from the second housing, the molecular diagnostic apparatus further comprising a second circuit board provided on a side of the first housing facing the second housing, the second circuit board being electrically connected to the second heating member, the third heating member and the control circuit board, respectively, the second circuit board being responsive to control of the control circuit board to drive the third heating member to heat the detection chamber and/or to drive the second heating member to heat the sample application chamber.

16. The molecular diagnostic apparatus according to claim 1, wherein the second heating member is provided on the cartridge detection seat, the molecular diagnostic apparatus further comprising:

17. The molecular diagnostic device according to claim 16, wherein the test card test receptacle comprises:

18. The molecular diagnostic device according to claim 17, wherein the test card cartridge further comprises:

19. The molecular diagnostic device according to claim 18, wherein the plurality of loading chamber mounting seats are provided, the plurality of elastic members are provided, the plurality of loading chamber mounting seats are provided in one-to-one correspondence with the plurality of elastic members, the plurality of elastic members are respectively abutted against the supporting plate, and the supporting plate is mounted on a side of the supporting seat main body away from the supporting seat main body on which the detection card is mounted.

20. The molecular diagnostic device according to claim 18, wherein the loading chamber mount comprises:

21. The molecular diagnostic apparatus according to claim 20, wherein the detection card is provided with a flow channel to communicate the sample loading chamber and the detection chamber, and the mount body is provided with an abutting portion at one side edge for abutting against a portion of the detection card where the flow channel is provided for heating.

22. The molecular diagnostic device according to claim 16, wherein the pressure plate comprises:

23. The molecular diagnostic apparatus according to claim 22, wherein the compression member is provided with a relief portion such that the loading chamber is disposed within the relief portion, and the fourth heating member is configured to heat in abutment with the loading chamber disposed within the relief portion.

24. The molecular diagnostic apparatus according to any one of claims 22 to 23, wherein the first heating member is provided on the pressure plate main body, the molecular diagnostic apparatus further comprising a second circuit board provided on the pressure plate main body, the second circuit board being electrically connected to the first heating member, the fourth heating member, the electromagnetic member and the control circuit board, respectively, the second circuit board being responsive to control of the control circuit board to drive the first heating member to heat the detection chamber and/or to drive the fourth heating member to heat the sample application chamber, the second circuit board being responsive to control of the control circuit board to energize the electromagnetic member.

25. A molecular diagnostic device, comprising:

26. A molecular diagnostic device, comprising: