CN116688365A - Brain stimulation guiding device, system and application - Google Patents

Brain stimulation guiding device, system and application Download PDF

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Publication number
CN116688365A
CN116688365A CN202210175852.9A CN202210175852A CN116688365A CN 116688365 A CN116688365 A CN 116688365A CN 202210175852 A CN202210175852 A CN 202210175852A CN 116688365 A CN116688365 A CN 116688365A
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positioning
brain
head
stimulation
brain stimulation
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缪婉
黄河
李圳
何姣燕
宫进昌
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Nanjing Vishee Medical Technology Co Ltd
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Nanjing Vishee Medical Technology Co Ltd
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Priority to CN202210175852.9A priority Critical patent/CN116688365A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/004Magnetotherapy specially adapted for a specific therapy
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00Materials specially adapted for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P10/00Technologies related to metal processing
    • Y02P10/25Process efficiency

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Materials Engineering (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

The application discloses a guiding device, a system and an application for brain stimulation, wherein the guiding device comprises a stimulation device, a follow-up positioning device and a positioning guide plate which is worn on the head and the face of a patient and is printed in a 3D way, a plurality of guiding parts are integrally formed on the positioning guide plate, the stimulation device is matched with the guiding parts, and the follow-up positioning device is attached to the head and the neck of a therapist and provides supporting force and freedom of movement for the stimulation device. The guiding device realizes perfect combination of the 3D printing technology and the follow-up positioning technology, and has the advantages of accurate positioning, high repetition precision, comfort for patients and the like. On the basis of a brain stimulation device, a brain stimulation system is built by combining an image processing system and a 3D modeling system, and the processing, the separation, the three-dimensional reconstruction, the registration, the guide plate model design and the like of medical image data are realized, so that the brain stimulation system has a good application prospect in the treatment of depression, cerebral apoplexy, aphasia, spasm, insomnia, obsessive compulsive disorder and other diseases in invalid medicaments and psychological treatment.

Description

Brain stimulation guiding device, system and application
Technical Field
The application relates to a guiding device, in particular to a brain stimulation guiding device, a system and application thereof; belongs to the technical field of medical equipment.
Background
The magnetic stimulation is to release the energy stored in the capacitor into the stimulating coil in a short time according to the principle of electromagnetic induction, so as to form a pulse current, and then form a pulse magnetic field and an induced electric field in the space nearby the pulse current. When the stimulating coil stimulates the human body, induced current is generated in the nerve tissue of the human body, and the cell membrane of the nerve cell is depolarized, so that action potential is generated. Different effects can be produced according to different stimulation positions, so that the brain stimulation technology is suitable for treating nervous system diseases such as depression, migraine and the like.
In the case of brain stimulation treatment, it is important to locate nerve stimulation points on the skull. The brain stimulation device in the prior art generally provides a navigation positioning device and a positioning method of a transcranial magnetic stimulator through matching a mechanical arm with a binocular/monocular vision positioning navigation system, such as a Chinese patent CN106110507A, and adopts a tracking technology that the vision positioning navigation system is matched with a multi-degree-of-freedom mechanical arm to clamp a head, so that the tracking technology has higher cost and higher use environment, and the problem of control interference of magnetic stimulation high-frequency radiation on a robot needs to be solved. The applicant also finds that the device has high requirements on the specificity of the treatment room and can generate the following errors: repeated positioning errors caused by the process quality of the mechanical arm, visual errors caused by insufficient resolution of a visual system, space coordinate calculation errors caused by a mechanical arm control algorithm, deformation errors caused by image processing software in the nuclear magnetic resonance image processing process, layer thickness errors, errors of generated coordinates after processing, head movement errors generated in the nuclear magnetic resonance image shooting process and the like can greatly reduce the treatment effect.
In view of this, there is a need for technological innovations to overcome the above-described problems.
Disclosure of Invention
In order to solve the defects in the prior art, the application aims to provide a guiding device and a guiding system for brain stimulation, and also discloses the application direction of the brain stimulation system.
In order to achieve the above object, the present application adopts the following technical scheme:
the application discloses a guiding device for brain stimulation, which comprises a stimulation device, a follow-up positioning device and a positioning guide plate worn on the head and the face of a patient, wherein the positioning guide plate is printed by 3D printing, a plurality of guiding parts are integrally formed on the positioning guide plate, the stimulation device is matched with the guiding parts, and the follow-up positioning device is attached to the head and the neck of a therapist and provides supporting force and freedom of movement for the stimulation device.
Preferably, the positioning guide plate is integrally formed by 3D printing, and may be an integral cover attached to the forehead of the patient.
Or, the positioning guide plate is of another structure and comprises a face support frame and a head treatment frame, wherein the contour line of the face support frame is attached to the forehead of a patient, and the head treatment frame is attached to the top of the head of the patient, so that the head is quickly and accurately positioned to a focus area during brain stimulation treatment; in particular, a blank space is formed between the face support and the head treatment support, which results in a higher patient comfort and cost savings, as compared to a fully wrapped helmet positioning device, while also achieving a better treatment.
More preferably, the guiding component is any structure for rapidly positioning the stimulation device to the treatment area, and in particular may be any one selected from a sticking type, a snap type or a jogged type structure (such as a guiding ring).
Preferably, the positioning guide plate is printed by a 3D printing material, and a photosensitive resin material or a nylon material can be selected, and the materials have better biocompatibility. The photosensitive resin is further preferable because the photosensitive resin is molded quickly, is easy to machine and polish, and has elasticity.
Preferably, the aforementioned stimulation device is a magnetic stimulation beat head, an electrical stimulation head or a deep invasive stimulation head.
Specifically, the magnetic stimulation head is one of a round head, a 8-shaped head, a butterfly head and a conical head, and correspondingly, the guiding component is matched with the head in an adaptation mode.
More preferably, positioning holes are formed at two ends of the face support frame of the positioning guide plate, and the follow-up positioning device is provided with a clamping piece connected with the positioning holes, so that even if the head moves during the treatment of a patient, the follow-up positioning device can carry the stimulation device to follow the movement, and the treatment effect is not affected.
Still preferably, the aforementioned follow-up positioning device is a follow-up headrest or a follow-up positioning helmet. The follow-up headrest can comprise a neck pillow and a follow-up device, wherein the neck pillow is a soft bag so as to improve comfort level, the neck pillow is connected with the follow-up device through a locking mechanism, and the locking mechanism can provide elastic deformation and traction force to realize real-time tracking of the body position of a patient. The following positioning helmet can be used in the prior art, such as the applicant's prior application 202021575339.1.
Based on the guiding device, the application also discloses a brain stimulation system, which comprises: the mechanical control system (controlling the stimulation device to the treatment area/location) and the treatment parameter system (controlling and adjusting the frequency, parameters, etc. of the system) are similar to the prior art, so that no further description is given in the present application. Furthermore, the system further comprises: a guiding device for brain stimulation, a medical image processing system and a 3D modeling system as described above; the medical image processing system is used for realizing data acquisition, processing, registration, disease fitting and target area coordinate calculation, so that personalized positioning can be carried out on the corresponding diseases, a face model containing target area characteristics is obtained, an equal ratio three-dimensional model of the head and the brain of a patient is reconstructed, and the face model is sent to the 3D modeling system; the 3D modeling system is used for digitally designing the model, designing the guide part and the contour line according to the position characteristic information of the specific indication acquired by the medical image processing system, finally generating a positioning guide plate model and transmitting the positioning guide plate model to the 3D printer, and obtaining the positioning guide plate through 3D printing.
Preferably, the medical image processing system comprises a data processing module, a structure positioning module, a function positioning module, an image display module and a result output module; the data processing module acquires medical image data and performs split processing on the medical image data to acquire personalized brain region area outline to be treated; the structure positioning module obtains the outline of the brain region to be treated of the structure position according to the image data, and forms position characteristic data of a target spot and a guide pin; the functional positioning module acquires the personalized regional outline of the brain region to be treated according to the functional connection of the brain region, and forms the position characteristic data of the target spot and the guide pin; the image display module is used for intuitively displaying the plane and the stereoscopic image in the interface and sending the plane and the stereoscopic image to the 3D modeling system through the result output module.
Further preferably, the aforementioned data processing module includes: the device comprises a data acquisition unit, an image segmentation unit, a functional area identification unit, a normal mode registration unit and an auxiliary functional unit; the structure positioning module comprises a normal mode registration unit and an auxiliary positioning unit, the function positioning module comprises a function area identification unit and an auxiliary positioning unit, the image display module comprises a plane editing unit, a three-dimensional processing unit and a display adjusting unit, and the result output module comprises a coordinate conversion unit and a format conversion unit; the data acquisition unit sends acquired medical image data to the image segmentation unit; the image segmentation unit segments medical image data into outer surface data including facial contours and brain data; the normal mode registration unit registers the internal brain file to a coordinate system; the functional area identification unit processes the brain area data to obtain the brain area outline of the personalized area to be treated; the auxiliary positioning unit generates a center point by taking the outline of the brain region area, takes a virtual target point as an incident point, generates a virtual guide pin perpendicular to the scalp, and forms a convex mark at the end of the guide pin to form two-dimensional data of the target point and the guide pin; the coordinate conversion unit forms a coordinate system according to the characteristic coordinates of the human body, and converts the treatment target point into coordinate information which can be read by the follow-up positioning device; the format conversion unit outputs data containing the treatment target in a form readable by a three-dimensional modeling system; the plane editing unit is used for performing operations such as rotation, scaling, level switching and the like on the image.
Further preferably, the image display module further includes a model transparency unit for adjusting a display effect of the model.
The brain stimulation system can carry out targeted auxiliary treatment on patients suffering from depression, aphasia, cerebral apoplexy, insomnia and anxiety, and has remarkable effect on patients suffering from depression, which are not effective in medicine and psychological treatment.
The beneficial effects are that:
(1) The brain stimulation guiding device is based on the positioning guide plate of 3D printing, is connected with the stimulation device and the follow-up positioning device, realizes perfect combination of the 3D printing technology and the follow-up positioning technology, and has the advantages of accurate positioning, high repetition precision, comfort for patients and the like.
(2) Based on the brain stimulation device, the brain stimulation system is built by combining the image processing system and the 3D modeling system, so that the medical image data is processed, split, the face model is reconstructed in a three-dimensional mode, registered, the guide plate model is designed, and the like, and finally, the market popularization of the brain stimulation system is realized, so that the brain stimulation system has a good application prospect in diseases with ineffective medicaments such as depression, insomnia and anxiety and psychological treatment.
Drawings
Fig. 1 is a schematic view showing the structure of the brain stimulation guide device according to the present application in a use state.
FIG. 2 is a unitary covered positioning guide of the present application.
Fig. 3 is a block diagram of the brain stimulation system of the present application.
Meaning of reference numerals in the drawings: 1. the head is clapped 2, follow-up headrest 3, location baffle, 31, guide ring, 32, facial support frame, 33, head treatment frame, 4, holder.
Detailed Description
The application is described in detail below with reference to the drawings and the specific embodiments.
In the description of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present application. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
Example 1
The structure of the guiding device for brain stimulation of the embodiment is shown in fig. 1, and the guiding device comprises a head 1, a follow-up headrest 2, and a positioning guide plate 3 worn on the head and the face of a patient, wherein the positioning guide plate 3 is printed by 3D printing, and a plurality of guiding rings 31 are integrally formed on the positioning guide plate 3. The number of the guide rings 31 in this embodiment is specifically 3, and the layout is as shown in fig. 1. The stimulation coil is arranged on the head 1 and is embedded with the guide ring 31, and the follow-up headrest 2 is attached to the head and neck of a therapist and provides supporting force and freedom of movement for the head 1. Therefore, the integral guiding device has the advantages of being rapid and accurate in positioning, enabling the head 1 to track the body position of a patient in real time, and the like, so that comfort level of the patient is improved, and treatment effect is optimized.
In practical application, the magnetic stimulation head 1 is only one of stimulation devices, and can also adopt stimulation devices of the types such as an electric stimulation head or a deep invasive stimulation head; furthermore, the guiding ring 31 is not limited to the embedded guiding ring in the present embodiment, and may be of a paste type, a snap type, or the like, so long as the structure capable of positioning and guiding the stimulation device to the area to be treated quickly falls within the scope of the present application.
In addition to the use of the follower headrest 2 of the present embodiment, the positioning helmet of the prior application 202021575339.1 may be used. When the helmet is applied, the human body characteristic coordinate system is matched with the coordinate system of the helmet, and the magnetic stimulation coil in the helmet is moved through the mechanical control system, so that the coil focus is stimulated on the position of the treatment target point, and the treatment scheme is set according to the treatment parameter adjusting system.
The positioning guide 3 is preferably made of biocompatible material and formed integrally by 3D printing technology, and can be made of photosensitive resin material or nylon material, preferably photosensitive resin material, with higher comfort. Specifically, the positioning guide 3 includes a face support 32 and a head treatment frame 33, the contour line of the face support 32 is attached to the forehead of the patient, the head treatment frame 33 is attached to the top of the head of the patient, as shown in fig. 1, so that the head 1 can be rapidly and accurately positioned to the focus area (target spot) during brain stimulation treatment, and the sliding of the positioning guide 3 during treatment can be avoided. It should be noted that, in the present embodiment, a blank space (such as the exposed forehead shown in fig. 1) is formed between the face support 32 and the head treatment frame 33, which saves cost and achieves better treatment effect compared to the fully wrapped helmet positioning device in the prior art.
In practical application, the whole cover without the blank area can be adopted, as shown in fig. 2, and meanwhile, the whole cover is not a magic tape, so that the whole cover is a sticking type guiding structure.
The head 1 of the guiding device of the application can be selected at will, such as a round head, a 8-shaped head, a butterfly head and a conical head, and correspondingly, the guiding ring 31 is matched with the head.
In order to further optimize the follow-up effect, positioning holes (which are blocked in the figure and are not shown) are formed at two ends of the face support frame 32 of the positioning guide plate 3, and the follow-up headrest 2 is provided with clamping pieces 4 connected with the positioning holes, so that even if the head moves during the treatment of a patient, the follow-up headrest 2 can carry the head 1 to follow the movement in real time, thereby ensuring that the treatment effect is not affected.
As a further improvement of this embodiment, the following headrest 2 may be further divided into a neck pillow and a following device, where the neck pillow is a soft bag to improve comfort, and is connected with the following device through a locking mechanism, where the locking mechanism can provide elastic deformation and traction force, so as to better implement real-time tracking of the patient's body position.
Example 2
The guiding device of embodiment 1 is used for constructing a brain stimulation system, so that accurate, rapid and repeated positioning of stimulation targets is realized to realize brain stimulation treatment. As shown in fig. 3, the system includes a mechanical control system, a treatment parameter system, a medical image processing system, and a 3D modeling system in addition to the aforementioned guiding devices. The structure and the function of the mechanical control system and the treatment parameter system are similar to those of the prior art, the medical image processing system is used for realizing data acquisition, processing, registration, disease fitting and target region coordinate calculation, obtaining a face model containing target region characteristics, reconstructing an equal ratio three-dimensional model of the head and the brain of a patient, and sending the model to the 3D modeling system; the 3D modeling system performs digital design on the model, designs the guide ring 31 and the contour line, and finally generates a positioning guide plate 3 model and sends the positioning guide plate 3 model to the 3D printer.
The medical image processing system comprises a data processing module, a structure positioning module, a function positioning module, an image display module and a result output module.
The data processing module acquires medical image data and performs split processing on the medical image data to acquire personalized brain region area outline to be treated, and the method specifically comprises the following steps: the data acquisition unit and the image segmentation unit. The data acquisition unit sends the acquired medical image data to the image segmentation unit; the image segmentation unit segments the medical image data into outer surface data including a face contour and brain data.
The structure positioning module obtains the outline of the brain region to be treated of the structure position according to the image data, and forms position characteristic data of the target point and the guide pin; the functional positioning module acquires the personalized outline of the brain region to be treated according to the functional connection of the brain region, and forms the position characteristic data of the target spot and the guide pin. The structure positioning module comprises a normal mode registration unit and an auxiliary positioning unit, and the function positioning module comprises a function area identification unit and an auxiliary positioning unit. Processing the brain region data through the functional region identification unit to obtain the brain region outline of the personalized region to be treated; the normal mode registration unit registers the internal brain file to a coordinate system; and finally, generating a center point by using the outline of the brain region area through an auxiliary positioning unit, generating a virtual guide needle perpendicular to the scalp by using a virtual target point as an incidence point, increasing the refraction angle of the scalp to indicate that the magnetic field coil deflects at the skull of the scalp, ending the guide needle on the scalp, and forming a convex mark at the ending end to form two-dimensional data of the target point and the guide needle.
The image display module is used for intuitively displaying the plane and the stereoscopic image in an interface, such as an equal-ratio three-dimensional model of the head and the brain of a patient, and sends the model to the 3D modeling system through the result output module. The 3D modeling system performs digital processing on the surface of the face model, and outputs a guide plate model in a 3D printing readable format.
For a better understanding and implementation of the present application, its process is briefly set forth below in connection with the system:
the system collects the original data from the optical disc or other paths, divides the original data into external head data and internal brain data, and then performs positioning in two ways:
(1) The structural positioning mode is as follows: and extracting brain data of MRI or CT of the patient, inducing a treatment target area of an effective treatment crowd onto a conventional model, aligning an interested area in the conventional model marked with the treatment target area with the brain data of the patient, registering the treatment target point to a specific position of the brain data of the patient in a deformation mode, and obtaining position characteristic information of the treatment target area according to the whole original data.
(2) Functional positioning mode: extracting fMRI and brain data of MRI of a patient, registering the fMRI of the patient on the MRI, preprocessing nuclear magnetic resonance images to remove interference information, finding out some areas with definite structural characteristics as reference areas, reflecting brain functional activity information with time variability such as cerebral blood oxygen and the like by voxel variation of the reference areas, screening available information by a filter, judging the positions of the areas communicated with the reference areas or the positions of the appointed increase and decrease variation of the information according to synchronous change of the time variation information, and obtaining the position characteristic information of the functional target area according to the whole original data.
After the positioning is finished, image display and achievement output can be performed, the model is digitally designed through a 3D modeling system, a positioning guide plate model is generated, and the positioning guide plate model is sent to a 3D printer for printing.
In summary, the brain stimulation guiding device is connected with the head 1 and the follow-up headrest 2 based on the positioning guide plate 3 of 3D printing, perfect combination of the 3D printing technology and the follow-up positioning technology is realized, and the guiding device has the advantages of accurate positioning, high repetition precision, comfort for patients and the like. The further developed brain stimulation system realizes the processing, the splitting, the three-dimensional reconstruction of a face model, the registration, the design of a guide plate model and the like of medical image data, and finally realizes the marketing popularization of the brain stimulation system, so that the brain stimulation system has a better application prospect in depression, aphasia, cerebral apoplexy, insomnia, anxiety and other related diseases with ineffective medicaments and psychological treatment.
In the description of the present application, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present application will be understood in specific cases by those of ordinary skill in the art.
In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present application. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing has shown and described the basic principles, principal features and advantages of the application. It will be appreciated by persons skilled in the art that the above embodiments are not intended to limit the application in any way, and that all technical solutions obtained by means of equivalent substitutions or equivalent transformations fall within the scope of the application.

Claims (15)

1. The utility model provides a guiding device for brain stimulation, its characterized in that includes stimulation device, follow-up positioner, still includes one and wears in the location baffle of patient's head face, the location baffle is printed by 3D, and integrated into one piece has a plurality of guide parts on the location baffle, stimulation device with guide part cooperatees, follow-up positioner laminating in therapist's head neck and for stimulation device provides holding power and freedom of movement.
2. The brain stimulation guide according to claim 1, wherein the positioning guide is made by 3D printing and is a unitary cover that fits over the forehead of the patient.
3. The brain stimulation guide according to claim 1, wherein the positioning guide plate comprises a face support frame and a head treatment frame, the outline of the face support frame is attached to the forehead of the patient, the head treatment frame is attached to the top of the head of the patient, and a blank space is formed between the face support frame and the head treatment frame.
4. The brain stimulation guide according to claim 1, wherein the guide member is configured to rapidly position the stimulation device to the treatment area, and is selected from any one of a stick-type, a snap-type, and a fitting-type structure.
5. The brain stimulation guide according to claim 1, wherein the positioning guide is printed from 3D printing material.
6. The brain stimulation guide according to claim 5, wherein the 3D printing material is a photosensitive resin material or a nylon material.
7. A brain stimulation guide according to claim 1, wherein the stimulation device is a magnetic stimulation beat head, an electrical stimulation head or a deep invasive stimulation head.
8. The brain stimulation guide of claim 7, wherein the magnetic stimulation head is one of a round head, a figure 8 head, a butterfly head, or a conical head.
9. A brain stimulation guide according to claim 3, wherein the positioning guide plate has positioning holes formed at both ends of the face support frame, and the follow-up positioning device has a clip member connected to the positioning holes.
10. The brain stimulation guiding device according to claim 1, wherein the follow-up positioning device is a follow-up headrest or a follow-up positioning helmet.
11. A brain stimulation system, comprising: a mechanical control system and a treatment parameter system, further comprising: the brain stimulation guiding device, medical image processing system and 3D modeling system according to any one of claims 1-10;
the medical image processing system is used for realizing data acquisition, processing, registration, disease fitting and target region coordinate acquisition, obtaining a face model containing target region characteristics, reconstructing an equal ratio three-dimensional model of the head and the brain of a patient, and sending the model to the 3D modeling system;
the 3D modeling system is used for digitally designing the model, designing the guide part and the contour line according to the position characteristic information of the specific indication acquired by the medical image processing system, finally generating a positioning guide plate model and transmitting the positioning guide plate model to the 3D printer, and obtaining the positioning guide plate through 3D printing.
12. The brain stimulation system according to claim 11, wherein the medical image processing system comprises a data processing module, a structure positioning module, a function positioning module, an image display module, and a result output module;
the data processing module acquires medical image data and performs splitting processing on the medical image data to acquire segmented image data and patient data;
the structure positioning module obtains the outline of the brain region to be treated of the structure position according to the image data, and forms position characteristic data of a target spot and a guide pin;
the functional positioning module acquires the personalized brain region area outline to be treated of the corresponding disease according to the functional connection of the brain region, and forms the position characteristic data of the target spot and the guide pin;
the image display module is used for intuitively displaying the plane and the stereoscopic image in the interface and sending the plane and the stereoscopic image to the 3D modeling system through the result output module.
13. The brain stimulation system according to claim 12, wherein said data processing module comprises: the structure positioning module comprises a normal mode registration unit and an auxiliary positioning unit, the function positioning module comprises a function area identification unit and an auxiliary positioning unit, the image display module comprises a plane editing unit, a three-dimensional processing unit and a display adjusting unit, and the result output module comprises a coordinate conversion unit and a format conversion unit;
the data acquisition unit sends acquired medical image data to the image segmentation unit;
the image segmentation unit segments medical image data into outer surface data including facial contours and brain data;
the normal mode registration unit registers the internal brain file to a standard brain template coordinate system;
the functional area identification unit processes the brain area data to obtain the brain area outline of the personalized area to be treated;
the auxiliary positioning unit generates a center point by taking the outline of the brain region area, takes a virtual target point as an incident point, generates a virtual guide pin perpendicular to the scalp, and forms a convex mark at the end of the guide pin to form two-dimensional data of the target point and the guide pin;
the coordinate conversion unit forms a coordinate system according to the characteristic coordinates of the human body, converts the treatment target point into coordinate information which can be read by the follow-up positioning device and outputs the coordinate information to the mechanical control system;
the format conversion unit outputs head data containing a treatment target point in a readable form of a three-dimensional modeling system;
the plane editing unit is used for performing rotation, scaling and level switching operations on the images.
14. The brain stimulation system according to claim 13, wherein the image display module further comprises a model transparency unit for adjusting the display effect of the model.
15. The use of a brain stimulation system according to any one of claims 11-14 for brain stimulation assisted therapy of depression, aphasia, stroke, insomnia and anxiety.
CN202210175852.9A 2022-02-25 2022-02-25 Brain stimulation guiding device, system and application Pending CN116688365A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210175852.9A CN116688365A (en) 2022-02-25 2022-02-25 Brain stimulation guiding device, system and application

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Application Number Priority Date Filing Date Title
CN202210175852.9A CN116688365A (en) 2022-02-25 2022-02-25 Brain stimulation guiding device, system and application

Publications (1)

Publication Number Publication Date
CN116688365A true CN116688365A (en) 2023-09-05

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Country Link
CN (1) CN116688365A (en)

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