CN116637255A

CN116637255A - Micro-dose adjusting method for needleless injection device

Info

Publication number: CN116637255A
Application number: CN202310440918.7A
Authority: CN
Inventors: 张亚
Original assignee: Zhuoyou Medical Suzhou Co ltd
Current assignee: Zhuoyou Medical Suzhou Co ltd
Priority date: 2023-04-23
Filing date: 2023-04-23
Publication date: 2023-08-25
Anticipated expiration: 2043-04-23
Also published as: CN116637255B

Abstract

The invention relates to a micro-dose adjustment method for a needleless injection device, comprising the steps of: providing a needleless injection device; maintaining the needleless injection device in a vertical state and directing the needleless injection head toward a facial region of the injection subject; acquiring a first facial image of the facial region by an image acquisition unit; selecting a target micro-dose of a corresponding facial area according to the first facial image, and generating a first adjusting signal based on the target micro-dose to send to a second adjusting module; the user or the second adjusting module adjusts the first adjusting module to the target position according to the first adjusting signal, or the user or the second adjusting module checks whether the first adjusting module is adjusted to the target position according to the first adjusting signal. The invention provides the regulating method which can be manually operated and automatically operated to flexibly switch to regulate the micro dose, and the method is beneficial to realizing the automatic operation of needleless injection, reducing the manual workload of a user and reducing the risk of misoperation.

Description

Micro-dose adjusting method for needleless injection device

Technical Field

The invention relates to the field of medical equipment, in particular to a micro-dose adjusting method for a needleless injection device.

Background

The needleless injection is an injection mode without a traditional capillary needle, does not need to be pricked into the body through the needle, but uses a needleless injection pusher to generate certain pressure through a driving module with stable mechanical property, and pushes the liquid medicine to be dispersed and injected into subcutaneous tissues of a patient under the action of the pressure. The needleless injection does not produce wounds in the injection process, so that the pain and fear of the patient in needling meat can be reduced to a certain extent.

However, the application of the existing needleless injection technology is relatively limited, the existing needleless injection products are often suitable for rapid injection in a short time (such as single vaccine injection, etc.), and the injection period of most medical projects is relatively long and frequent injection is required (for example, the water injection time can last 40-50 minutes according to the injection requirements of different injection objects, and for example, the hyaluronic acid injection needs about 30-60 minutes). Therefore, when the conventional needleless injection product is applied to the medical field with long injection period and frequent and multiple injections, various operation pain points such as difficult single-hand operation, difficult dosage adjustment, difficult heat dissipation, complicated operation and the like exist.

For example, needleless injection technology also places higher demands on the operating efficiency, stability of the drive module in order to be able to provide a needleless injector with sufficient injection pressure. For example, chinese patent application publication No. CN108452405a discloses an electromagnetic driving device for needleless injection, which overcomes the defect of low reliability caused by the fact that the current must be controlled to achieve the limit in the prior art. Although the electromagnetic driving device can improve the working stability to a certain extent (realizing the reliable limit of the needle tube), the electromagnetic driving device also has the problems of heavy weight, large volume, large heat and the like, which can increase the operation difficulty of operators to a certain extent.

In addition, in order to facilitate manual operation by an operator, the prior art has attempted to provide a needleless injector in a pistol shape, however, the needleless injector in the pistol shape has a relatively limited application range, and is generally more suitable for a range of situations such as rapid vaccine injection in a shoulder region.

For example, chinese patent application publication No. CN102652848A discloses an electromagnetic type continuous needleless injector with adjustable dose and injection depth, the whole external shape of which is designed in the shape of a pistol for the convenience of the operator.

However, since the needleless injector should be maintained in a state of being perpendicular to the injection area during the injection, for an injection item (such as a hydro-optical injection applied to the face) in which the injection subject needs to lie down, the injection posture of the pistol shape during the injection may rather cause inconvenience to the operator (it will be understood that the hand of the operator needs to be maintained in a large curved posture so that the injection needle of the pistol is perpendicular to the face area of the injection subject). In other words, such pistol-shaped injectors are often suitable for use in a rapid injection scenario where the subject is sitting (e.g., when the subject is sitting, the shoulder is injected with a vaccine).

In addition, the dosage adjustment of the needleless injector has the problems of complex operation and difficult accurate quantitative adjustment. Specifically, when the operator needs to adjust the dose, a wrench that rotates the internal hex (or other structure) is inserted into the housing (11) from a small hole in the rear of the housing and engages the internal hex (or other structure) on the core (12). It is evident that this adjustment by means of external tools is not convenient and that the adjustment requires the operator to press the iron core in order to bring it against the spring force of the return spring (10) to the position of the injection stop), and that this manual pressure application process also presents difficulties in the regulation of the dosage values, in particular for the adjustment of micro-doses, such as 0.5 ml.

For another example, chinese patent publication No. CN101690834a discloses a continuous needleless injection system driven by electromagnetic force, the whole appearance of which is also designed as a pistol appearance, and the pistol appearance also has the problems of difficult single-hand use and inability to accurately adjust dosage when applied to the medical field.

Disclosure of Invention

The invention aims to provide a semi-automatic operation mode capable of realizing mutual cooperative cooperation of manual operation and automatic operation, which can be suitable for injection scenes such as hormones, medical and aesthetic injection, auxiliary reproduction injection and the like.

In order to solve the above-mentioned technical problems, the present invention specifically adopts the following technical scheme, and a micro-dose adjusting method for a needleless injection device includes:

s401 provides a needleless injection device comprising: a housing; the first end of the housing is provided with an injection module for containing a liquid, the injection module comprising: a needleless injection head and a push rod; a magnetic driving module is arranged in the shell, and a rotor component in the magnetic driving module can drive the pushing rod to reciprocate, so that the liquid is injected or received; the first adjusting module is also arranged in the shell and used for adjusting the moving range of the rotor assembly;

s402 maintaining the needleless injection device in a vertical state and orienting the needleless injection head toward a face area of an injection subject;

s403, acquiring at least one first facial image of the facial area through an image acquisition unit;

s404, selecting a target micro-dose corresponding to the facial area according to the first facial image, and generating a first adjusting signal based on the target micro-dose to be sent to a second adjusting module;

s405 the user or the second adjustment module adjusts the first adjustment module to a target position according to the first adjustment signal, and the user or the second adjustment module verifies whether the first adjustment module is adjusted to the target position according to the first adjustment signal after the adjustment is completed.

In some embodiments, the first adjustment module comprises: the first rotating part and the second rotating part are meshed with the first rotating part, and the second rotating part can reciprocate along the axial direction under the drive of the first rotating part, so that the moving range of the rotor assembly in the reciprocating process is adjusted; wherein the first rotating part includes: a first rotating member engaged with the second rotating portion, and a second rotating member coaxially rotated with the first rotating member, the first rotating member protruding outward through the opening of the housing, the second rotating member being provided with a plurality of limit protrusions around the axial direction, and the housing

A limiting groove matched with the limiting protrusion is correspondingly arranged in the inner part;

accordingly, the S405 includes:

s51, the second adjusting module determines a target rotation angle of the first rotating piece according to the first adjusting signal;

s52, the second adjusting module adjusts the first rotating piece to a target position according to the target rotating angle.

In some embodiments, the second adjustment module comprises: a securing structure for securing the needleless injection device, and an adjustment structure for adjusting the first rotating member, the adjustment structure comprising:

And a driving unit for driving the third rotating member to rotate.

In some embodiments, the limit protrusion is provided with a dose identifier, and the housing is further provided with a visible opening corresponding to the limit protrusion, where the visible opening is used for observing a dose identifier corresponding to the current rotation angle, and accordingly, S405 includes the steps of:

judging whether the dose identifier observed by the current rotation angle is matched with the target micro dose or not; if not, the first rotating member is corrected and adjusted, or a prompt signal is sent to a user.

In some embodiments, the mover assembly of the needleless injection device in S401 comprises: a second hollow frame, wherein a first end of the second hollow frame is slidably mounted inside the stator assembly through a sliding component, and the sliding component is also connected with the pushing rod;

the mover assembly further includes: a buffer member provided at an outer periphery of the sliding member, the buffer member including: an elastic member provided at an outer periphery of the second end of the sliding member; when the rotor assembly is kept in a vertical state, the elastic component is in contact with the wall surface of the sliding component, so that the tendency of displacement of the sliding component and the second hollow framework due to the action of gravity is limited or reduced.

In some embodiments, in the needleless injection device in S401, a plurality of first protrusions are provided on the inner side of the housing in the axial direction, adjacent side walls of the first protrusions together form a first groove, and the first groove penetrates through the first end cover and the second end cover on two sides of the housing, so that a plurality of heat dissipation openings are formed on the first end cover and the second end cover;

the first grooves form a plurality of heat dissipation air channels distributed along the circumferential direction of the magnetic drive motor, and heat generated by the magnetic drive motor in the starting process can be guided out along the circumferential direction of the magnetic drive motor and is discharged through heat dissipation openings on two sides of the shell under the guidance of the heat dissipation air channels.

In some embodiments, prior to S404, further comprising:

collecting a plurality of second facial images of the injection object, and performing skin detection on a plurality of facial areas of the injection object according to the second facial images to obtain corresponding skin information;

determining target microdose of the plurality of facial regions according to the skin information;

adding a marker to the second facial image according to the target microdose, the marker comprising: the target microdose.

In some embodiments, S404 includes:

comparing and searching the first facial image with at least one pre-stored second facial image, wherein the second facial image is a pre-acquired facial image of the injection object, and the second facial image is marked with a target micro-dose;

when at least one second facial image is searched to be matched with the first facial image, acquiring the mark information of the second facial image;

and determining the target micro-dose of the corresponding facial area according to the marking information.

In some embodiments, prior to S404, further comprising the step of:

determining, by the first facial image, positional information of the facial region, the positional information including: coordinate data;

judging whether the distance between the face area and the preset non-injection area meets a preset safety threshold or not, and if not, sending a corresponding warning signal to the user.

In some embodiments, comprising:

s406 adding a marker to the first facial image according to the actual injection dose, the marker comprising:

true injection dose;

s407 stores the marked first facial image in an object database.

The beneficial technical effects are as follows:

the invention provides a micro-dose adjusting method capable of being coordinated with human and machine, which can be matched with the existing system to realize automatic determination and adjustment of dose, and meanwhile, when the injection safety is relatively high and the manual intervention of an operator is needed, the operator can conveniently take down the needleless injector to manually operate. The manual and automatic flexible switching mode can better meet the injection requirements in the current micro-high frequency injection scene.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. Like elements or portions are generally identified by like reference numerals throughout the several figures. In the drawings, elements or portions thereof are not necessarily drawn to scale. It will be apparent to those of ordinary skill in the art that the drawings in the following description are of some embodiments of the invention and that other drawings may be derived from these drawings without inventive faculty.

FIG. 1 is a schematic view of a needleless injection device in accordance with an exemplary embodiment of the present invention;

FIG. 2 is a schematic diagram of a first adjustment module according to an exemplary embodiment of the present invention;

FIG. 3 is a schematic diagram of a first internal structure of a first adjustment module according to an exemplary embodiment of the present invention;

FIG. 4 is a schematic diagram of a second internal structure of the first adjustment module according to an exemplary embodiment of the present invention;

FIG. 5 is a schematic cross-sectional view of a magnetic drive module in an exemplary embodiment of the invention;

FIG. 6 is a schematic view of a needle-free injection device according to yet another exemplary embodiment of the present invention;

FIG. 7 is a schematic view showing a first internal structure of a needleless injection device in accordance with still another exemplary embodiment of the present invention;

FIG. 8 is a schematic view of a second internal structure of a needleless injection device in accordance with yet another exemplary embodiment of the present invention;

FIG. 9 is a schematic cross-sectional view of the needleless injection device of FIG. 7;

FIG. 10 is a schematic view showing a partial structure of a mover assembly according to an exemplary embodiment of the present invention;

FIG. 11 is a schematic view of a housing according to an exemplary embodiment of the present invention;

FIG. 12 is a schematic view of the front end cap structure of a needleless injection device in accordance with an exemplary embodiment of the present invention;

FIG. 13 is a schematic view of a first adjustment module of a needleless injection device in accordance with another exemplary embodiment of the present invention;

FIG. 14 is a schematic view of the needleless injection device of FIG. 13;

FIG. 15 is a schematic view of a first cross-sectional configuration of the needleless injection device of FIG. 13;

FIG. 16 is a schematic view of a portion of the first adjustment module of FIG. 13;

FIG. 17 is a schematic diagram illustrating the cooperation between the special-shaped rotating portion and the limiting block in the first adjusting module shown in FIG. 13;

FIG. 18 is a schematic view of a second cross-sectional configuration of the needleless injection device of FIG. 13;

fig. 19 is a schematic structural view of a special-shaped rotating portion according to an exemplary embodiment of the present invention;

FIG. 20 is a schematic view of a partial structure of a second adjustment module according to an exemplary embodiment of the present invention;

FIG. 21 is a block diagram of an automated control system in an exemplary embodiment of the invention;

fig. 22 is a semi-automated control method in an exemplary embodiment of the invention.

Reference numeral identification summary:

10 is an injection module; 20 is a shell; 21 is a start switch; 22 is a first adjusting module, 22-1 is a first rotating piece, 22-2 is a second rotating piece, 22-3 is a second rotating part, and 22-4 is a buffer pad;

23 is a rotor component, 23-1 is an insulating partition plate, 23-2 is a lead mounting groove, 23-3 is an isolation pipeline, 23-4 is a sliding component, 23-41 is an annular sliding block, and 23-42 is a wear-resistant ring; 23-5 is a second hollow framework, 23-51 is a shock pad, 23-52 is a supporting spring, and 23-53 is a limiting block; 24 is an electronic control module;

25 is a stator assembly, 25-1 is a first hollow framework, 25-2 is a permanent magnet; 26-1 is a front end cover, 26-11 is a first cover plate, and 26-12 is a second cover plate; 26-2 is a rear end cover, 26-21 is a rotating path, 26-22 is a second positioning opening, 27-1 is a first protrusion, and 27-2 is a first groove; 28 is a special-shaped rotating part, 28-1 is a step, 28-2 is a first auxiliary rotating piece, 28-3 is a second auxiliary rotating piece, and 28-4 is a first positioning opening; 31 is a fixed structure, 32 is a third rotating member, and 33 is a driving unit; 40 is a computer and 50 is a control system.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. It will be apparent that the described embodiments are some, but not all, embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

In this document, suffixes such as "module", "component", or "unit" used to represent elements are used only for facilitating the description of the present invention, and have no particular meaning in themselves. Thus, "module"

"component" or "unit" may be used in combination.

The terms "upper," "lower," "inner," "outer," "front," "rear," "one end," "the other end," and the like herein refer to an orientation or positional relationship based on that shown in the drawings, merely for convenience of description and to simplify the description, and do not denote or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be construed as limiting the invention. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

The terms "mounted," "configured to," "connected," and the like, herein, are to be construed broadly as, for example, "connected," whether fixedly, detachably, or integrally connected, unless otherwise specifically defined and limited; the two components can be mechanically connected, can be directly connected or can be indirectly connected through an intermediate medium, and can be communicated with each other. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.

Herein, "and/or" includes any and all combinations of one or more of the associated listed items.

Herein, "plurality" means two or more, i.e., it includes two, three, four, five, etc.

It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.

As used in this specification, the term "about", typically expressed as +/-5% of the value,

more typically +/-4% of the value, more typically +/-3% of the value, more typically +/-2% of the value, even more typically +/-1% of the value, even more typically +/-0.5% of the value.

In this specification, certain embodiments may be disclosed in a format that is within a certain range. It should be appreciated that such a description of "within a certain range" is merely for convenience and brevity and should not be construed as a inflexible limitation on the disclosed ranges. Accordingly, the description of a range should be considered to have specifically disclosed all possible sub-ranges and individual numerical values within that range. For example, a range

The description of (c) should be taken as having specifically disclosed sub-ranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., as well as individual numbers within such ranges, e.g., 1,2,3,

4,5 and 6. The above rule applies regardless of the breadth of the range.

Herein, "face image" refers to image information (such as a skin photograph) obtained by image acquisition of the face of an injection subject in whole or in part. For example, it may be a full-face photograph, or a partial photograph of the tail part, forehead part, chin, nose bridge, lips, cheekbones, or the like. Wherein, skin detection process does: and carrying out binarization processing on the facial image, and carrying out skin color detection according to the binarization result. For example, alternative skin detection methods include, but are not limited to: HSV color space H range screening method, ellipse skin color detection model, cr component+Otsu method threshold segmentation algorithm of YCrCb color space, gesture recognition of BGR space, cr, cb range screening method, etc.

Herein, a "non-injection region" is a region of the face that needs to be avoided during injection. Taking the water photo needle project as an example, the positions near the lips, the temple, the surrounding of the nose and the like are usually required to be avoided.

Herein, the "real injection dose" is an actual injection dose to the current face region. Which is typically the target microdose. Of course, in some embodiments, the target micro-dose may also be manually adjusted to account for the particular condition of the subject being injected (skin care requirements or skin characteristics, etc.), where the actual injected dose is recorded as a value after manual adjustment.

As used herein, "vertical" or "perpendicular to each other" refers to a plane in which a needleless injection device (specifically, a needleless injection head) and an injection area (e.g., a human face) of an injection subject are perpendicular or nearly perpendicular to each other, so as to ensure that a medicament can smoothly pass through the skin of the injection subject.

Herein, a "user" may refer to a worker (e.g., healthcare worker or the like) performing an injection procedure,

and may also refer to a computer or other medical system (e.g., skin detector, etc.) coupled to the needleless injection device.

Example 1

As shown in fig. 1-21, the present invention provides a needleless injection device using a magnetically driven motor in order to be able to accommodate the long and frequent injection needs of medical injection procedures.

As shown in fig. 1, the needleless injection device includes: a housing 20, an injection module 10 disposed at a first end of the housing, the injection module comprising: a needleless injector head, a pusher capable of reciprocating along a cavity of the needleless injector head; when the pushing rod moves at a high speed along the injection direction, liquid (such as hormone, heparin, a water optical needle or hyaluronic acid and other medicaments) in the needleless injection head can be pushed to enable the medicament to generate high pressure in the needleless injection head, the high pressure medicament can form an extremely fine water needle through the outlet end of the needleless injection head, the instant potential energy of the water needle breaks through skin cuticle with a certain thickness and then is rapidly dispersed in skin dermis tissue with a fixed depth, and therefore noninvasive medicament injection is achieved.

A magnetic drive motor (i.e., a magnetic drive module) disposed inside the housing, the magnetic drive motor comprising: a front end cover, a rear end cover, and a stator assembly (also referred to as a stator) 25 and a mover assembly (also referred to as a mover) 23 disposed between the front end cover 26-1 and the rear end cover 26-2, the mover assembly being capable of reciprocating in an axial direction of the stator assembly and driving the push rods to move synchronously; wherein the stator assembly comprises: the first hollow framework 25-1 is respectively connected with the front end cover and the rear end cover, the plurality of annular permanent magnets 25-2 are arranged on the inner side of the first hollow framework, and the outer side of the first hollow framework is wrapped with a magnetic insulating sleeve; the mover assembly includes: the second hollow framework 23-5 is arranged on the inner side of the first hollow framework, a plurality of insulating partition boards 23-1 are arranged on the second hollow framework at intervals, a plurality of groups of wire groups are correspondingly arranged among the insulating partition boards, a wire mounting groove 23-2 for guiding wires is also arranged on the second hollow framework, a plurality of isolation pipelines 23-3 are also arranged at the second end of the second hollow framework, and the wires sequentially pass through the rear end cover along the wire mounting groove and the isolation pipelines; and an electronic control module 24 disposed adjacent to the rear end cap and connected to the magnetically driven motor.

In some embodiments, the plurality of wire sets collectively disposed on the second hollow skeleton are connected in parallel, for example, three sets of enameled wires are provided to be energized in parallel.

In this embodiment, in order to reduce the overall volume of the needleless injection device, the multi-line groups which are arranged in parallel and in a concentrated manner are adopted to cooperate with the permanent magnets to generate enough electromagnetic force, so that the rotor assembly can generate larger acceleration in a limited moving range, and enough pressure is applied to the medicament to form the ultrafine water needle.

Further, in order to avoid the local heat generated by the centrally arranged wire set being too high, as shown in fig. 3, in some embodiments, a plurality of first protrusions (also equivalent to reinforcing structures) 27-1 are arranged on the inner side of the shell along the axial direction, adjacent side walls of the first protrusions jointly form a first groove 27-2, and the first groove penetrates through the first end cover and the second end cover on two sides of the shell, so that a plurality of heat dissipation openings are formed on the first end cover and the second end cover;

the first grooves form a plurality of heat dissipation air channels distributed along the circumferential direction of the magnetic drive motor, and heat generated by the magnetic drive motor in the starting process can be guided out along the circumferential direction of the magnetic drive motor and is discharged through heat dissipation openings on two sides of the shell under the guidance of the heat dissipation air channels. Specifically, in the process of reciprocating movement of the mover assembly, air in the shell is guided to flow along the axial direction (namely the movement direction of the mover) to a certain extent, and at the moment, heat generated in the vicinity of the mover assembly can be outwards dissipated along the openings at the two ends of the heat dissipation air duct under the driving of air flow. In addition, because the radiating air duct is arranged along the annular direction and is provided with openings at two ends of the shell, when an operator or a mechanical hand holds the needleless injection device for injection, the working of the radiating air duct is not disturbed.

In some embodiments, the first groove is an arcuate groove, such as a semi-circular groove.

In some embodiments, as shown in fig. 8, the mover assembly includes: a sliding member 23-4 provided at a first end of the second hollow frame, the second hollow frame being slidably mounted inside the first hollow frame by the sliding member, and a second end of the sliding member 23-4 being connected to the push rod; wherein, the mover assembly further comprises: and a buffer member provided on an outer periphery of the sliding member.

Specifically, as shown in fig. 8, in some embodiments, both ends of the second hollow frame are provided with sliding members 23-4 for supporting and mounting the second hollow frame inside the stator assembly (specifically, the first hollow frame 25-1), and the sliding members can drive the second hollow frame to slide/move relatively with respect to the first hollow frame.

In some embodiments, as shown in fig. 8, the sliding member disposed near the front end cover includes:

the annular sliding block 23-41 connected with the first end of the second hollow framework, at least one wear-resistant ring 23-42 is arranged on the outer side of the annular sliding block, and when the rotor assembly is installed inside the magnetic drive motor through the annular sliding block, the rotor assembly is in contact with the stator assembly through the wear-resistant ring, so that abrasion and vibration of the rotor assembly in the frequent injection process are reduced to a certain extent.

In particular, in some embodiments, the first end of the annular slider is connected to the second hollow skeleton,

the second end of the annular slider (i.e. the second end of the sliding member) protrudes upwards to form a boss (the boss is preferably provided in a cylindrical structure), wherein the boss can pass through an opening provided in the first cover plate and the boss is also connected with the push rod.

In some embodiments, as shown in fig. 7, the cushioning component includes: the shock pad 23-51 is arranged between the front end cover and the sliding part, and can weaken the vibration action of the rotor component when impacting the front end cover, so that the working stability of the needleless injection device is improved, and the single-hand use of an operator is facilitated.

In some embodiments, as shown in fig. 7, the cushioning component includes: an elastic member (preferably, a support spring 23-52) provided at the outer periphery of the second end of the sliding member; when the mover assembly pushes the pushing rod under the action of gravity, the elastic component is contacted with the wall surface of the sliding component so as to limit the displacement of the sliding component.

It will be appreciated that for most medical injection projects, the subject is typically receiving an injection in a lying position, taking into account the length of the injection and the particularities of the injection procedure. Thus, it is desirable to keep the needleless injection head perpendicular to the face of the subject during injection. The design of the shock pad and the supporting spring in the embodiment can avoid the phenomenon of liquid leakage of the needleless injection head when the needleless injection head is vertically placed.

Specifically, since the mover assembly has a certain dead weight, when the whole needleless injection device is in a vertical state, the mover assembly falls down under the action of gravity so as to apply a certain pressure to the pushing rod, thereby causing the needleless injection head to leak. And the supporting springs and the damping pads can reduce the falling speed and the falling distance of the rotor assembly in the falling process, so that the liquid leakage phenomenon is reduced or relieved.

In some embodiments, the injection module further comprises a reservoir connected to the needleless injector head (e.g.,

can be a card bottle which is fixed outside the shell through a mounting bayonet), the needleless injection head can be a single-needle or multi-needle injection head, and when the pushing rod retreats, the liquid in the liquid storage bottle is sucked into the needleless injection head. Wherein, the liquid storage bottle and the needleless injection head can be flexibly disassembled and replaced so as to be convenient for replacement after each injection is completed.

In some embodiments, the front and rear end caps are respectively mated with the housing (preferably made of plastic) by a snap-fit arrangement.

In some embodiments, the front end cap 26-1 includes: the first cover plate 26-11 fixedly connected with the shell is provided with an opening for the second end of the sliding component (namely, the end connected with the pushing rod) to pass through, the first cover plate is outwards protruded along the edge of the opening to form a second cover plate 26-12, a hollow area of the second cover plate provides a reciprocating movement path for the pushing rod and the sliding component, and the buffer component is arranged on the inner side of the first cover plate and/or the second cover plate.

In some embodiments, a cooperating region is disposed proximate the second end of the housing, the cooperating region defining a cooperating path along an axial direction of the housing, the cooperating paths being sequentially disposed along: a start switch 21, a first adjustment module (also called dose adjustment module) and a display module, and the display module is arranged in a region corresponding to the electronic control module and is in communication with the electronic control module.

In some embodiments, the display module may display one or more of the following information: the target microdose to be injected, the type of agent (e.g., name, etc.), the injected dose, the remaining injected dose, the adjusted dose, etc.

In some embodiments, the magnetically driven motor further comprises: an iron core for increasing the electromagnetic density,

the iron core is arranged on the inner side of the second hollow framework.

In some embodiments, the first hollow armature is made of a magnetically isolated material.

In some embodiments, the housing of the stator assembly employs an aluminum motor housing for isolating the magnetic field from the outside.

In some embodiments, the front end cover and the rear end cover are also aluminum end covers, which also play a role in magnetic field isolation for the external and the electric control module at the rear end of the motor, and ensure the electromagnetic compatibility of the electric equipment.

The needleless injection device provided by the embodiment of the invention can be applied to injection of medicines such as medical and aesthetic medicines, hormones (for example, insulin injection), heparin required by auxiliary reproduction and the like.

The technical scheme and beneficial technical effects of the invention are further described below by taking a water optical needle project as an example. Generally, the total injection amount of the hydro-optical needle is about 5-10ml, but the total amount of 5-10ml is needed to be injected to different points (such as forehead, chin, nose bridge, lips, etc.) on the face through multiple micro-dose injections. Moreover, the micro-dose injected from different facial points is different in consideration of the difference of skin conditions (such as darkness, color spots, etc.) of different injection subjects or different facial areas of the same injection subject. Thus, during hydro-optical injection, it is often necessary to frequently inject different microdose (e.g., only 0.5ml or less of medicament for sensitive areas) at various points on the face of the subject. Such frequent medicament sampling and medicament injection on the one hand generates high heat inside the housing, and requires fast and accurate adjustment of the injected microdose by the operator.

In some embodiments, the apparatus further comprises: a second adjusting module connected with the electric control module,

The second adjustment module includes:

an image acquisition unit configured to acquire at least one first facial image (i.e., a partial photograph) of a facial region of an injection subject when the needleless injection device is in a vertical state and the injection module is aligned with the facial region;

a dose selection unit configured to select a target micro-dose corresponding to the facial region from the first facial image and generate a first adjustment signal based on the target micro-dose to send to the electronic control module;

wherein the electronic control module is further configured for verifying whether the first adjustment module is adjusted to a target position based on the first adjustment signal.

For example, in some embodiments, whether to turn on the image capture unit may be selected by a user (specifically, an activation signal may be sent to the image capture unit by the electronic control module).

In some embodiments, further comprising: a pretreatment module connected with the second regulation module,

the preprocessing module is configured to acquire a plurality of second facial images of the injection object, and perform skin detection on a plurality of facial areas of the injection object according to the second facial images so as to acquire corresponding skin information; determining target microdose of the plurality of facial regions according to the skin information; adding a marker to the second facial image according to the target microdose, the marker comprising: the target microdose;

Accordingly, the dose selection unit comprises:

a first subunit configured to compare the first facial image with at least one of the second facial images; when at least one of the second facial images is retrieved to match the first facial image (e.g., photo texture matches), obtaining marking information for the second facial image;

a second subunit configured to determine the target microdose for a corresponding facial region from the marker information.

Further, in some embodiments, a first adjustment module 22 for adjusting an injection dose, the first adjustment module comprising: a first rotating part and a second rotating part 22-3 meshed with the first rotating part, wherein the second rotating part can reciprocate along the axial direction under the drive of the first rotating part, so as to adjust the moving range of the rotor assembly in the reciprocating process; wherein the first rotating part includes: a first rotary member 22-1 and a second rotary member 22-2 which are coaxially rotated, wherein,

the first rotating piece is meshed with the second rotating part, a plurality of limiting protrusions are arranged on the second rotating piece along the axial direction of the second rotating piece, and at least one limiting groove matched with the limiting protrusions is correspondingly arranged on the shell.

Further, in some embodiments, a dose identifier is disposed on the limiting protrusion, and a visible opening is further disposed on the housing corresponding to the limiting protrusion, where the visible opening is used for observing a dose identifier corresponding to the current rotation angle, and correspondingly, the second adjusting module further includes: a dose verification module configured to determine whether the dose indicator observed by the current rotation angle matches the target micro-dose; if not, the first rotating member is corrected and adjusted, or a prompt signal is sent to a user.

In some embodiments, further comprising: a data management module connected with the second regulating module,

is configured for adding a marker to the first facial image in accordance with a true injected dose, the marker comprising: true injection dose; and storing the marked first facial image into an object database.

In some embodiments, the second adjustment module further comprises:

a risk early warning unit configured to determine location information of the face area from the first face image, the location information including: coordinate data; and judging whether the distance between the face area and the non-injection area meets a preset safety threshold, and if not, sending a first warning signal to the electronic control module.

Example two

The invention also provides a method of dose adjustment for a needleless injection device for a magnetically driven motor,

to facilitate automated drug injection, the method comprising the steps of:

s101 provides a needleless injection device as described in any one of embodiments one;

s102, enabling the needleless injection device to keep a vertical state and enabling the needleless injection head to face the face area of an injection object;

s103, acquiring at least one first facial image of the facial area through an image acquisition unit;

s104, selecting a target micro-dose corresponding to the facial area according to the first facial image, and generating a first adjusting signal based on the target micro-dose to send to a second adjusting module;

and S105, the user or the second adjusting module adjusts the first adjusting module to a target position according to the first adjusting signal.

In particular, in some embodiments, the second adjustment module may be communicatively coupled to the electronic control module, or the second adjustment module and the electronic control module may be configured as the same module.

In some embodiments, the first adjustment module comprises: a first rotating part and a second rotating part 22-3 meshed with the first rotating part, wherein the second rotating part can reciprocate along the axial direction under the drive of the first rotating part, so as to adjust the moving range of the rotor assembly in the reciprocating process; wherein the first rotating part includes: the first rotating member 22-1 meshed with the second rotating portion 22-3, and the second rotating member 22-2 coaxially rotating with the first rotating member 22-1, wherein the first rotating member protrudes outwards through the opening of the shell, a plurality of limit protrusions are arranged on the second rotating member around the axial direction, and limit grooves matched with the limit protrusions are correspondingly arranged in the shell;

Accordingly, the S105 includes:

In some embodiments, the second adjustment module comprises: a fixing structure 31 for fixing the needleless injection device, and an adjusting structure for adjusting the first rotating member, the adjusting structure comprising: a third rotating member 32 engaged with the first rotating member, and a driving unit 33 for driving the third rotating member 32 to rotate.

In some embodiments, the limit protrusion is provided with a dose identifier, and the housing is further provided with a visible opening corresponding to the limit protrusion, where the visible opening is used for observing a dose identifier corresponding to the current rotation angle, and accordingly, S105 includes the steps of:

The embodiment of the invention provides a micro-dose adjusting or verifying method which can be manually operated and mechanically operated in cooperation with each other. The manual and mechanical cooperative characteristic ensures that the method not only can reduce the manual operation workload of a user, but also can ensure the efficiency and operation safety of the whole injection process (the mode of automatic dose adjustment and dose inspection can accurately control the tiny dose). Meanwhile, when the device is applied to a real medical injection project, the manual and mechanical flexible conversion mode can be flexibly adapted to the real-time operation requirement of medical staff.

For example, in some embodiments, the second adjustment module may be configured as a robotic mechanism (as shown in fig. 20 and 21) or may cooperate with a robotic mechanism or the like, and may automatically perform dose adjustment, injection procedures during a medical injection procedure under the supervision of a user (e.g., a doctor). When the injection difficulty is relatively high (such as for the important areas like the adjacent eye area or for the injection of the injection object with relatively complex skin condition), the beatifying doctor can conveniently take down the needleless injection device from the manipulator and adopts a manual operation mode to carry out the dosage adjustment and the injection.

In some embodiments, prior to S104, further comprising:

Preferably, in some embodiments, the method may be combined with an existing control system (e.g., a skin detection device connected to a computer), wherein skin analysis is first performed on the facial skin of the subject by the control system to determine the total injected dose and the target microdose for the different regions, and then injection is sequentially performed for each of the different regions according to the target microdose.

In some embodiments, S104 comprises:

In some embodiments, the method further comprises the step of:

In some embodiments, further comprising:

s106, adding marks to the first facial image according to the actual injection dose, wherein the marks comprise:

true injection dose;

s107 stores the marked first facial image in an object database.

In the embodiment of the invention, an automatic dose adjustment design is adopted, so that the data acquisition and management of the real injection information (such as the injection dose and the injection area) can be more conveniently carried out, and the injection information of the injection object can be conveniently monitored and managed for a long time by a user.

Example III

In order to accurately adjust the micro-dose in the frequent injection process, the invention also provides a micro-adjustable needleless injection device. The needleless injection device is convenient for manual adjustment and can realize automatic adjustment. Also, the needleless injection device may comprise any one or more of the same modules or structural components of the embodiments described above.

For example, in some preferred embodiments, the needleless injection device comprises: a housing, a housing 20 disposed at a first end of the housing, an injection module 10, the injection module comprising: a needleless injector head, a pusher capable of reciprocating along a cavity of the needleless injector head;

a magnetic drive motor disposed inside the housing, the magnetic drive motor comprising: the front end cover, the rear end cover, and the stator assembly 25 and the rotor assembly 23 arranged between the front end cover 26-1 and the rear end cover 26-2, wherein the rotor assembly can reciprocate along the axial direction of the stator assembly and drive the pushing rod to synchronously move;

And a dose adjustment module (also referred to as a first adjustment module 22, as shown in fig. 3) for adjusting an injected dose, the dose adjustment module comprising: the first rotating part (specifically, the first rotating part can be fixed on the rear end cover through a supporting pin), and the second rotating part 22-3 (specifically, a mounting opening is formed on the rear end cover for the second rotating part to pass through so as to realize reciprocating motion) meshed with the first rotating part, and the second rotating part can reciprocate along the axial direction under the driving of the first rotating part, so that the moving range of the rotor assembly in the reciprocating motion process is adjusted.

Preferably, in some embodiments, as shown in fig. 3, the first rotating part includes: the first rotating member 22-1 and the second rotating member 22-2 coaxially rotate, wherein the first rotating member 22-1 is meshed with the second rotating portion 22-3, the second rotating member 22-2 is provided with a plurality of limiting protrusions along the axial direction thereof, and the shell is correspondingly provided with at least one limiting groove matched with the limiting protrusions.

In some embodiments, the diameter of the first rotating member is greater than the diameter of the second rotating member,

A first opening is formed in a region, corresponding to the first rotating part, of the shell; the first opening includes: the mounting area is used for enabling the first rotating piece to protrude to the outer side of the shell, and the visual area is used for observing the rotating state of the second rotating piece, wherein the second rotating piece is arranged on the inner side of the shell.

In some embodiments, the size of the limit projection is greater than the size of the rotating tooth of the first rotating member.

In some embodiments, the limit protrusions are arc protrusions (e.g., semicircular protrusions), and the limit grooves are correspondingly configured as arc grooves.

In order to achieve labor-saving and accurate micro-dose adjustment in the embodiment, a dose adjustment mode based on double rotating members is designed. Wherein, the first rotation piece of direct control movable range adopts small-size design (specifically, the periphery of first rotation piece evenly is provided with a plurality of micro-teeth) can realize laborsaving operation. Meanwhile, the large-size arc-shaped bulge design of the second transmission piece can assist an operator to accurately position, when the second transmission piece rotates to the state that one arc-shaped bulge and one arc-shaped groove are mutually matched (namely, the bulge is completely clamped in the groove), the arc-shaped groove in turn can apply certain resistance to the rotation piece to limit the rotation piece to further rotate, and therefore the operator can judge whether the second transmission piece rotates in place or not through handfeel (such as whether the second transmission piece is subjected to resistance).

In some embodiments, a dose indicator is disposed on the limit projection.

In some embodiments, the first end of the second rotating part is meshed with the first rotating part, and a buffer module is arranged on one side of the second rotating part, which corresponds to the rotor assembly, so as to reduce the vibration effect of the rotor assembly, which impacts the rear end cover in the medicine taking process, and improve the working stability of the needleless injection device.

In some embodiments, the buffer module comprises: cushion 22-4; the second end of the second rotating part is provided with a first positioning groove or a first positioning bulge, and the buffer cushion is correspondingly provided with a second positioning bulge or a second positioning groove.

For example, in some embodiments, the second end of the second rotating portion is provided with a first positioning groove, and the positioning groove is a trapezoidal groove (specifically, the cross section of the positioning groove is configured as a trapezoid) with a gradually decreasing opening, so as to further limit the displacement of the cushion pad.

In some embodiments, the first rotating portion is mounted on the rear end cover through a fixing piece, and the second rotating portion is also rotatably connected with the rear end cover (specifically, an opening is provided on the rear end cover, the second rotating portion can rotate back and forth through the opening, and the second end of the second rotating portion can also contact with the iron core).

Specifically, in some embodiments, the second rotating portion is threadably connected to the rear end cap.

In some embodiments, an electronic control module is disposed outside of the rear end cap and fixedly mounted on the rear end cap, wherein a reserved space is formed between the electronic control module and the rear end cap for mounting the dose adjustment module.

A starting switch and a display module which are connected with the electric control module are respectively arranged on two sides of the dose adjusting module; the display module is arranged in a region corresponding to the electric control module on the shell, and the starting switch, the dose adjusting module and the display module are arranged on the same straight line;

wherein the start switch, the dose adjustment module and the display module arranged along the line together form a cooperating path.

In some embodiments, the injection end of the needleless injection head is provided with an injection signal acquisition module,

the injection signal acquisition module is used for acquiring a pressure signal of the injection end, and sending a corresponding starting signal to the electronic control module when the pressure signal belongs to a preset threshold value so that liquid in the needleless injection head is injected.

Further, the dual rotational member of the present invention also enables automatic adjustment of microdose, and preferred embodiments for automatically enabling microdose adjustment are described below.

In some embodiments, the needleless injection device further comprises: the second regulation module is connected with the electronic control module, and the second regulation module comprises:

an image acquisition unit configured to acquire at least one first facial image of a facial region of an injection subject when the needleless injection device is in a vertical state and the injection module is aligned with the facial region;

For example, in some embodiments, a miniature camera is provided in the housing on a side of the housing adjacent to the needleless injection head for taking a photograph of the skin of the facial area (i.e., the first facial image). When a skin photo is taken, the target micro-dose of the current facial area is judged according to the skin state (such as whether a colored plate, darkness or red blood streak is present or not) of the facial area, and then the target micro-dose is sent to an electronic control module, and the electronic control module automatically adjusts the first adjusting module (for example, specifically, the first rotating member is rotated as shown in fig. 21).

the preprocessing module is configured to acquire a plurality of second facial images of the injection object, and perform skin detection on a plurality of facial areas of the injection object according to the second facial images so as to acquire corresponding skin information (such as whether a colored plate, a dark or red blood streak and the like); determining target microdose of the plurality of facial regions according to the skin information; adding a marker to the second facial image according to the target microdose, the marker comprising: the target microdose;

accordingly, the dose selection unit comprises:

a first subunit configured to compare the first facial image with at least one of the second facial images; when at least one second facial image is searched to be matched with the first facial image, acquiring the mark information of the second facial image;

In some embodiments, the limit protrusion is provided with a dose identifier, and the housing is further provided with a visible opening corresponding to the limit protrusion, where the visible opening is used for observing a dose identifier corresponding to the current rotation angle, and correspondingly, the second adjusting module further includes: a dose verification module configured to determine whether the dose indicator observed by the current rotation angle matches the target micro-dose; if not, the first rotating member is corrected and adjusted, or a prompt signal is sent to a user.

Preferably, the needleless injection device of the present embodiment is operated in a combination of manual and automated operation. For example, for injection subjects with relatively uniform facial skin tone, a fully automated dose adjustment approach may be employed. Aiming at uneven complexion or other scenes with higher requirements on injection operation, a manual operation or manual and automatic combination mode is adopted.

is configured for adding a marker to the first facial image in accordance with a true injected dose, the marker comprising: true injection dose; and storing the marked first facial image into an object database. In this embodiment, the needleless injection device may further collect values for each injection subject, so as to facilitate management of treatment information or injection information of the injection subject.

In some embodiments, the second adjustment module further comprises:

In some embodiments, the second adjustment module may include: a manipulator for gripping a needleless injection device (in particular, as shown in fig. 20, a partial structure of the manipulator may be provided as a fixed structure 31, wherein the fixed structure 31 may further be equipped with a movement actuator that moves spatially in a user-specified direction, thereby bringing the needleless injection device to different injection areas of an injection subject).

In particular, in some embodiments, the needleless injection device of the present invention can be provided directly on an existing injection system or injection device. For example, the needleless injection device of the present invention can directly replace the hydro-optical needle injection needle portion of the hydro-optical needle injection instrument of the prior art.

Example IV

According to the needleless injection device of the above embodiments, the present invention provides a micro-dose automatic adjustment method, comprising the steps of:

s201 maintaining the needleless injection device in a vertical state and orienting the needleless injection head toward an area to be injected (such as a facial area, a scalp area, or other areas) of an injection subject;

s202, acquiring at least one first facial image of the facial area through an image acquisition unit;

S203, selecting a target micro-dose corresponding to the face area according to the first face image by the dose selecting unit;

s204, generating a first adjusting signal based on the target micro-dose to send to a second adjusting module;

s205, the user or the second adjusting module adjusts the first adjusting module to the target position according to the first adjusting signal, or the user or the second adjusting module checks whether the first adjusting module is adjusted to the target position according to the first adjusting signal.

Accordingly, the S205 includes:

In some embodiments, the limit protrusion is provided with a dose identifier, and the housing is further provided with a visible opening corresponding to the limit protrusion, where the visible opening is used for observing a dose identifier corresponding to the current rotation angle, and accordingly, S205 includes the steps of:

The embodiment of the invention provides a micro-dose adjusting or verifying method which can be manually operated and mechanically operated in cooperation with each other. The manual and mechanical cooperative characteristic enables the method to reduce the manual operation workload of a user and flexibly adapt to the real-time operation requirement.

In some embodiments, prior to S204, further comprising:

In some embodiments, S204 comprises:

In some embodiments, the method further comprises the step of:

In some embodiments, further comprising:

s206, adding marks to the first facial image according to the actual injection dose, wherein the marks comprise:

true injection dose;

s207 stores the marked first facial image in an object database.

Example five

In some embodiments, the present invention also provides another micro-adjustable needleless injection device comprising a housing, an injection module 10 disposed at a first end of the housing, the injection module comprising: a needleless injector head, a pusher capable of reciprocating along a cavity of the needleless injector head;

A magnetic drive module disposed within the housing, the magnetic drive module comprising: the front end cover, the rear end cover, and the stator assembly 25 and the rotor assembly 23 arranged between the front end cover 26-1 and the rear end cover 26-2, wherein the rotor assembly can reciprocate along the axial direction of the stator assembly and drive the pushing rod to synchronously move; wherein,,

the stator assembly includes: the first hollow framework 25-1 is respectively connected with the front end cover and the rear end cover, the plurality of annular permanent magnets 25-2 are arranged on the inner side of the first hollow framework, and the outer side of the first hollow framework is wrapped with a magnetic insulating sleeve;

the mover assembly includes: a second hollow frame 23-5 provided inside the first hollow frame,

a plurality of insulating partition boards 23-1 are arranged on the second hollow framework, a plurality of groups of wire groups are correspondingly arranged among the insulating partition boards, a wire mounting groove 23-2 for guiding wires is also arranged on the second hollow framework, a plurality of isolation pipelines are also arranged at the second end of the second hollow framework, and the wires sequentially pass through the rear end cover along the wire mounting groove and the isolation pipelines;

an electronic control module 24 disposed adjacent to the rear end cap and connected to the magnetic drive module;

And a first adjustment module disposed at a second end of the mover assembly, the first adjustment module capable of realizing flexible conversion of manual operation and mechanical operation comprising: a special-shaped rotating part 28 capable of rotating along the circumferential direction of the rotor assembly, and limiting blocks 23-53 arranged at the second end of the second hollow framework;

as shown in fig. 18, a plurality of steps 28-1 with different heights are sequentially disposed on a first side of the special-shaped rotating portion 28, a first auxiliary rotating member 28-2 is disposed on a second side of the special-shaped rotating portion 28, and the first auxiliary rotating member 28-2 can reciprocate along a rotating path 26-21 disposed on the rear end cover, so as to drive the special-shaped rotating portion 28 to reciprocate;

when the profiled rotation part 28 rotates in the circumferential direction (i.e. around the axis of the cylindrical housing), the moving range of the mover assembly increases or decreases accordingly, wherein the distance between the step and the stopper on the same line as the stopper is the moving range.

In some embodiments, a plurality of elastic positioning members are further disposed inside the profiled rotating part 28 corresponding to the plurality of steps, and a plurality of first positioning openings 28-4 are further disposed on the second side of the profiled rotating part 28 corresponding to the plurality of elastic positioning members, wherein the elastic positioning members can protrude outwards through the first positioning openings 28-4 when no external force is applied;

The rear end cover is provided with at least one second positioning opening 26-22, wherein when one of the first positioning openings corresponds to the second positioning opening, the elastic positioning piece can extend into the second positioning opening, so that certain resistance is given to the rotation of the special-shaped rotating part, and a user can judge whether the special-shaped rotating part rotates in place or not through handfeel (namely, blocked force).

In some embodiments, the first adjustment module further comprises: the second auxiliary rotating member 28-3 is used for driving the first auxiliary rotating member 28-2 to rotate, and an opening for the second auxiliary rotating member 28-3 to rotate is correspondingly formed in the shell.

Further, in some embodiments, the second adjustment module for adjusting the first auxiliary rotating member 28-2 or the second auxiliary rotating member 28-3 further includes: a drive unit for adjusting a first auxiliary rotating member or a second auxiliary rotating member, the drive unit comprising: the output end of the arc motor can move along the arc guide rail. The output end of the arc-shaped motor can be connected with the first auxiliary rotating piece or the second auxiliary rotating piece so as to drive the first auxiliary rotating piece or the second auxiliary rotating piece to rotate.

For example, in some embodiments, the arc motor may be disposed at a position between the electronic control module and the magnetic driving module, where an output end of the arc motor is connected to the first auxiliary rotating member to drive the first auxiliary rotating member to rotate along a set angle.

For example, in some embodiments, the arc motor may be disposed outside the housing, and the output end of the arc motor is directly connected to the second auxiliary rotating member to drive the second auxiliary rotating member to rotate along the set angle.

In some embodiments, the second adjustment module comprises:

accordingly, the dose selection unit comprises:

In some embodiments, the second adjustment module further comprises:

Example six

Corresponding to the fifth embodiment, the invention further provides a micro-dose automatic adjustment method, comprising the steps of:

there is provided a needleless injection device as in any of embodiments five, wherein the second adjustment module comprises: a drive unit for adjusting a first auxiliary rotating member or a second auxiliary rotating member, the drive unit comprising: the output end of the arc motor moves along the arc guide rail and is connected with the first auxiliary rotating piece or the second auxiliary rotating piece so as to drive the first auxiliary rotating piece or the second auxiliary rotating piece to rotate;

maintaining the needleless injection device in a vertical state and orienting the needleless injection head toward a facial region of an injection subject;

Acquiring at least one first facial image of the facial region by an image acquisition unit; selecting, by a dose selection unit, a target micro-dose corresponding to the facial region according to the first facial image, and generating a first adjustment signal based on the target micro-dose for transmission to a second adjustment module;

the user or the second adjusting module adjusts the first adjusting module to the target position according to the first adjusting signal, or the user or the second adjusting module checks whether the first adjusting module is adjusted to the target position according to the first adjusting signal.

Accordingly, the S305 includes:

In some embodiments, the housing is provided with an opening for the second auxiliary member to protrude outwards,

the second auxiliary member can reciprocally rotate along the path provided by the opening, and dosage identifiers are arranged on the edge of the opening at intervals, and accordingly, S305 includes the steps of:

In some embodiments, prior to S304, further comprising:

In some embodiments, S304 comprises:

In some embodiments, the method further comprises the step of:

In some embodiments, further comprising:

s306 adds a marker to the first facial image according to the actual injected dose, the marker comprising:

true injection dose;

s307 stores the marked first facial image in an object database.

Example seven

Further, the invention also provides a micro-dose automatic adjusting method for the needleless injection device aiming at the needleless injection device in any embodiment.

For example, in some exemplary embodiments, a method includes:

s401 provides a needleless injection device comprising: a housing 20; the first end of the housing is provided with an injection module 10 for containing a liquid, the injection module comprising: a needleless injection head and a push rod; a magnetic driving module is arranged in the shell, and a rotor component in the magnetic driving module can drive the pushing rod to reciprocate, so that the liquid is injected or received;

And a first adjusting module for adjusting the moving range of the rotor assembly is further arranged in the shell.

s403, acquiring at least one first facial image (namely skin photo) of the facial area through an image acquisition unit;

s405, the user or the second adjusting module (or the electric control module) adjusts the first adjusting module to a target position according to the first adjusting signal, or the user or the second adjusting module checks whether the first adjusting module is adjusted to the target position according to the first adjusting signal.

Specifically, in some embodiments, S405 includes: the user or the second adjusting module adjusts the first adjusting module to a target position according to the first adjusting signal, and the user or the second adjusting module checks whether the first adjusting module is adjusted to the target position according to the first adjusting signal after the adjustment is completed.

accordingly, the S405 includes:

The embodiment of the invention provides a micro-dose adjusting or verifying method which can be manually operated and mechanically operated in cooperation with each other. The manual and mechanical cooperation feature enables the method to reduce the manual operation workload of a user, and the mode of automatic dose adjustment and dose inspection can accurately control the tiny dose. Meanwhile, when the method is applied to a real medical injection project, the mode of manual and mechanical flexible conversion can be flexibly adapted to the real-time operation requirement.

For example, in some embodiments, the second adjustment module may be configured as a robotic mechanism (as shown in fig. 20, 21) or may cooperate with a robotic mechanism or the like, and may automatically perform dose adjustment, injection procedures during a medical injection procedure under the supervision of a user (e.g., a cosmetist). When the injection difficulty is relatively high (such as for the important areas like the adjacent eye area or for the injection of the injection object with relatively complex skin condition), the beatifying doctor can conveniently take down the needleless injection device from the manipulator and adopts a manual operation mode to carry out the dosage adjustment and the injection.

In some embodiments, the mover assembly of the needleless injection device in S401 comprises: a second hollow frame, wherein a first end of the second hollow frame 23-5 is slidably mounted on the inner side of the stator assembly through a sliding part 23-4, and the sliding part 23-4 is also connected with the pushing rod;

the mover assembly further includes: a buffer member provided at an outer periphery of the sliding member, the buffer member including: an elastic member (i.e., support springs 23-52) provided at the outer periphery of the second end of the sliding member; when the rotor assembly is kept in a vertical state, the elastic component is in contact with the wall surface of the sliding component, so that the tendency of displacement of the sliding component and the second hollow framework due to the action of gravity is limited or reduced.

In some embodiments, the needleless injection device in S401 is provided with a plurality of first protrusions 27-1 on the inner side of the housing in the axial direction, adjacent side walls of the first protrusions together form a first groove 27-2, and the first groove penetrates through the first end cover and the second end cover on two sides of the housing, so that a plurality of heat dissipation ports are formed on the first end cover and the second end cover;

In some embodiments, prior to S404, further comprising:

In some embodiments, S404 includes:

In some embodiments, the method further comprises the step of:

For example, in some embodiments, the marking information of the second facial image further includes: the data of the coordinates are provided with a coordinate,

the coordinate data of the first facial image may be determined according to the matched marking information of the second facial image.

In some embodiments, further comprising:

true injection dose;

s407 stores the marked first facial image in an object database.

It will be appreciated that the needleless injection device or dose adjustment method of embodiments of the present invention, as illustrated in fig. 21, can be communicatively coupled to a computer 40, a control system 50 (which may be specifically various types of skin detection devices) to enable semi-automatic or fully automated microdose adjustment and injection.

It should be noted that the medical injection project is a preferred injection scene of the present invention, and of course, the injection device or the dose adjusting method of the present invention can also be applied to other injection scenes (such as vaccine injection, etc.).

From the above description of the embodiments, it will be clear to those skilled in the art that the above-described embodiment method may be implemented by means of software plus a necessary general hardware platform, but of course may also be implemented by means of hardware, but in many cases the former is a preferred embodiment. Based on such understanding, the technical solution of the present invention may be embodied essentially or in a part contributing to the prior art in the form of a software product stored in a storage medium (e.g. ROM/RAM, magnetic disk, optical disk) comprising several instructions for causing a computer terminal (which may be a mobile phone, a computer, a server, or a network device, etc.) to perform the method according to the embodiments of the present invention.

The embodiments of the present invention have been described above with reference to the accompanying drawings, but the present invention is not limited to the above-described embodiments, which are merely illustrative and not restrictive, and many forms may be made by those having ordinary skill in the art without departing from the spirit of the present invention and the scope of the claims, which are to be protected by the present invention.

Claims

1. A method of microdose adjustment for a needleless injection device, comprising:

s401 provides a needleless injection device comprising: a housing (20); the first end of the housing is provided with an injection module (10) for containing a liquid, the injection module comprising: a needleless injection head and a push rod; a magnetic driving module is arranged in the shell, and a rotor component in the magnetic driving module can drive the pushing rod to reciprocate, so that the liquid is injected or received; the first adjusting module is also arranged in the shell and used for adjusting the moving range of the rotor assembly; s402 maintaining the needleless injection device in a vertical state and orienting the needleless injection head toward a face area of an injection subject;

2. A micro-dose adjustment method for a needleless injection device as claimed in claim 1, in which the first adjustment module comprises: a first rotating part and a second rotating part (22-3) meshed with the first rotating part, wherein the second rotating part can reciprocate along the axial direction of the rotor assembly under the drive of the first rotating part, so as to adjust the moving range of the rotor assembly in the reciprocating process; wherein the first rotating part includes: a first rotating member (22-1) meshed with the second rotating portion (22-3), and a second rotating member (22-2) coaxially rotating with the first rotating member (22-1), wherein the first rotating member protrudes outwards through a shell opening, a plurality of limit protrusions are arranged on the second rotating member around the axial direction, and limit grooves matched with the limit protrusions are correspondingly arranged in the shell;

Accordingly, the S405 includes:

3. A micro-dose adjustment method for a needleless injection device as claimed in claim 2, in which the second adjustment module comprises: a fixing structure (31) for fixing the needleless injection device, and an adjusting structure for adjusting the first rotating member, the adjusting structure comprising: a third rotating member (32) engaged with the first rotating member, and a driving unit for driving the third rotating member (32) to rotate.

4. A micro-dose adjusting method for a needleless injection device as claimed in claim 2 or 3, in which a dose indicator is provided on the limit projection, and a visual opening is provided on the housing corresponding to the limit projection, the visual opening being used to observe the dose indicator corresponding to the current rotation angle, and in which S405 further comprises the steps of:

judging whether the dose identifier observed by the current rotation angle is matched with the target micro dose or not;

If not, the first rotating member is corrected and adjusted, or a prompt signal is sent to a user.

5. A micro-dose setting method for a needleless injection device as in claim 1, wherein said sub-assembly in S401 comprises: a second hollow skeleton, wherein a first end of the second hollow skeleton (23-5) is slidably arranged on the inner side of a stator assembly of the magnetic driving module through a sliding part (23-4), and the sliding part (23-4) is also connected with the pushing rod;

the mover assembly further includes: a buffer member provided at an outer periphery of the sliding member, the buffer member including: an elastic member (23-52) provided on the outer periphery of the second end of the sliding member; when the rotor assembly is kept in a vertical state, the elastic component is in contact with the wall surface of the sliding component, so that the tendency of displacement of the sliding component and the second hollow framework due to the action of gravity is limited or reduced.

6. A micro-dose adjusting method for a needleless injection device as claimed in claim 1, wherein a plurality of first protrusions (27-1) are provided on the inner side of the housing in the needleless injection device in S401 along the axial direction, adjacent side walls between the first protrusions together form a first groove (27-2), and the first groove penetrates through a first end cover and a second end cover on both sides of the housing, thereby forming a plurality of heat radiation ports on the first end cover and the second end cover;

The first grooves form a plurality of heat dissipation air channels distributed along the circumferential direction of the magnetic driving module, and heat generated by the magnetic driving module in the starting process can be guided out along the circumferential direction of the magnetic driving module and is discharged through heat dissipation openings on two sides of the shell under the guidance of the heat dissipation air channels.

7. A micro-dose setting method for a needleless injection device as claimed in claim 5, and further comprising, prior to S404:

8. A micro-dose setting method for a needleless injection device as claimed in claim 1, in which S404 comprises:

and determining the target micro-dose corresponding to the facial area according to the marking information.

9. A micro-dose setting method for a needleless injection device as claimed in claim 1, and comprising, prior to S404, the further step of:

10. A micro-dose setting method for a needleless injection device as claimed in claim 1, and further comprising:

s406 adding a marker to the first facial image according to the actual injection dose, the marker comprising: true injection dose;

s407 stores the marked first facial image in an object database.