CN116616994A - Automatic medicine injection equipment in blood vessel - Google Patents

Automatic medicine injection equipment in blood vessel Download PDF

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Publication number
CN116616994A
CN116616994A CN202310459977.9A CN202310459977A CN116616994A CN 116616994 A CN116616994 A CN 116616994A CN 202310459977 A CN202310459977 A CN 202310459977A CN 116616994 A CN116616994 A CN 116616994A
Authority
CN
China
Prior art keywords
injection
assembly
injection needle
needle
bearing housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202310459977.9A
Other languages
Chinese (zh)
Inventor
边桂彬
叶强
伊智诚
李桢
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Automation of Chinese Academy of Science
Original Assignee
Institute of Automation of Chinese Academy of Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Automation of Chinese Academy of Science filed Critical Institute of Automation of Chinese Academy of Science
Priority to CN202310459977.9A priority Critical patent/CN116616994A/en
Publication of CN116616994A publication Critical patent/CN116616994A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/00736Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286Needle tip design, e.g. for improved penetration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287Accessories for bringing the needle into the body; Automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3293Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle hub
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006Having specific accessories
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287Accessories for bringing the needle into the body; Automatic needle insertion
    • A61M2005/3289Accessories for bringing the needle into the body; Automatic needle insertion with rotation of the needle, e.g. to ease penetration
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The application provides a pressing device for avoiding hand contact, which comprises an injection assembly, an injection needle bending mechanism, an injection needle rotating mechanism, an injection needle delivery mechanism and a liquid medicine pushing mechanism. The injection assembly comprises an injection needle and an injection tube, wherein one end of the injection needle is connected with one end of the injection tube, the liquid medicine pushing mechanism is communicated with the other end of the injection tube, liquid medicine is stored in the liquid medicine pushing mechanism, and the liquid medicine can be pushed to the injection needle at a preset speed until being pushed into a blood vessel. The injection needle rotating mechanism comprises an injection needle outer sleeve and a rotating assembly, the injection needle rotating mechanism wraps the injection tube, the rotating assembly drives the injection assembly to rotate through the injection needle outer sleeve, the injection assembly is clamped by the injection needle delivering mechanism, the injection assembly is driven to move, the injection needle can be inserted into a blood vessel with reasonable strength, the injection needle bending mechanism is connected with the injection needle outer sleeve at the end part close to the injection needle, so that the injection needle is driven to bend, and the injection needle can be accurately inserted into the blood vessel of a patient.

Description

Automatic medicine injection equipment in blood vessel
Technical Field
The application relates to the technical field of medical equipment, in particular to a pressing device capable of avoiding hand contact.
Background
Retinal Vein Occlusion (RVO) is a worldwide important cause of vision decline in the elderly, and it manifests as thrombus formation in the center of retinal veins or branch vessels, resulting in serious vision loss and even blindness.
In order to ensure the safety and accuracy of Retinal Vein Occlusion (RVO) procedures, it is important to provide an intravascular automatic drug delivery device that assists the surgeon in the procedure.
Disclosure of Invention
The application provides intravascular automatic medicine injection equipment, which aims to at least solve the problems that an injection needle can be stably injected in a retina blood vessel, improve the positioning precision of the injection needle during intravascular puncture, and detect the puncture force of the injection needle in real time so that medicine can be stably pushed at a specified speed.
In view of the above, the present application provides an intravascular automatic drug delivery device, comprising: the injection assembly comprises an injection needle and an injection tube, and the injection needle is connected with one end of the injection tube; the liquid medicine pushing mechanism is connected with the injection assembly and is communicated with the other end of the injection tube; the injection needle rotating mechanism is connected with the injection assembly and comprises an injection needle external sleeve and a rotating assembly, the injection needle rotating mechanism is wrapped outside the injection tube, and the rotating assembly drives the injection assembly to rotate through the injection needle external sleeve; the injection needle bending mechanism is arranged on the injection needle rotating mechanism and is connected with the end part, close to the injection needle, of the injection needle external sleeve so as to drive the injection needle to bend; and the injection needle delivery mechanism clamps the injection assembly and drives the injection assembly to move.
In some alternative embodiments, the injection needle delivery device further comprises a base, and the injection needle rotating mechanism, the injection needle delivery mechanism and the liquid medicine pushing mechanism are sequentially arranged in the length direction of the base.
In some alternative embodiments, the base includes a support housing and a support plate, the support housing and the needle rotation mechanism being disposed on the support plate; the injection needle rotating mechanism, the injection needle bending mechanism and the injection needle delivery mechanism are arranged in the supporting shell, one ends of the injection needle and the injection tube are positioned outside the supporting shell, and the liquid medicine pushing mechanism penetrates through the supporting shell and is connected with the other end of the injection tube.
In some alternative embodiments, the medical fluid pushing mechanism comprises a first three-way valve, a second three-way valve, a medical injection hose, a pushing assembly, a servo motor lever, a pneumatic sensor, and a pressure sensor; the first three-way valve, the medicine injection hose, the pushing assembly and the servo electric lever are sequentially connected; the first three-way valve is respectively connected with the injection tube and the medicine injection hose; the second three-way valve sleeve is arranged on the pushing assembly, and the air pressure sensor is arranged on the second three-way valve; the pressure sensor is arranged on the servo motor rod.
In some alternative embodiments, the push assembly includes a drug-delivery sleeve and a compression assembly that is slidable within the drug-delivery sleeve; the extrusion assembly comprises a rubber piston, a sealing ring, a push rod and a push rod connector, wherein the rubber piston, the push rod and the push rod connector are sequentially connected, and the sealing ring is sleeved outside the rubber piston.
In some alternative embodiments, the rotating assembly includes a piezoelectric drive motor, a first coupling, and a second coupling, the piezoelectric drive motor being coupled to the first coupling and the second coupling, respectively, the first coupling being coupled to the syringe outer sleeve, the second coupling being coupled to the needle bending mechanism.
In some alternative embodiments, the needle bending mechanism comprises a first drive motor, a third coupling, an output shaft, a drive wire, a turntable, and a continuum component; the second shaft coupling with the carousel is connected, first driving motor set up in the carousel, first driving motor with the third shaft coupling is connected, output shaft connects the driving wire, the driving wire passes the outside sleeve of injection tube with the continuum part is connected.
In some alternative embodiments, the syringe further comprises a support member, one end of the support member is disposed on the housing of the piezoelectric driving motor, and the other end of the support member is connected with the syringe external sleeve through a first bearing.
In some alternative embodiments, the delivery needle delivery mechanism includes a fixed base plate, a second drive motor, and a bearing housing assembly, the fixed base plate, the second drive motor, and the bearing housing assembly being stacked, the injection tube extending through the bearing housing assembly.
In some alternative embodiments, the bearing housing assembly comprises a first bearing housing and a second bearing housing, the first bearing housing and the second bearing housing being arranged in a length direction of the syringe, the first bearing housing being provided with a first sleeve, the second bearing housing being provided with a second sleeve.
Compared with the prior art, the application has the following technical effects:
the application provides intravascular automatic drug injection equipment, which comprises: injection assembly, needle bending mechanism, needle rotation mechanism, needle delivery mechanism, and drug solution pushing mechanism. The injection assembly comprises an injection needle and an injection tube, wherein the injection needle is connected with one end of the injection tube, the liquid medicine pushing mechanism is communicated with the other end of the injection tube, liquid medicine is stored in the liquid medicine pushing mechanism, and the liquid medicine pushing mechanism can push the liquid medicine to the injection needle through the injection tube at a preset speed and stably until the liquid medicine is pushed to the inside of a patient body, so that the stable injection of the liquid medicine in retinal blood vessels can be ensured. The injection needle rotating mechanism comprises an injection needle outer sleeve and a rotating assembly, the injection needle rotating mechanism wraps the injection tube, the rotating assembly drives the injection assembly to rotate through the injection needle outer sleeve, the injection assembly is clamped by the injection needle delivering mechanism, the injection assembly is driven to move forwards or backwards, the injection needle can be inserted into a blood vessel with reasonable strength, the injection needle bending mechanism is connected with the injection needle outer sleeve, close to the end portion of the injection needle, so that the injection needle is driven to bend, the injection needle can be accurately inserted into the blood vessel of a patient, and the positioning accuracy of the injection needle during intravascular puncture is improved.
Drawings
The foregoing and/or additional aspects and advantages of the application will become apparent and may be better understood from the following description of embodiments taken in conjunction with the accompanying drawings in which:
FIG. 1 is a schematic view showing the structure of an intravascular automatic drug delivery device according to an embodiment of the present application;
FIG. 2 shows a schematic perspective view of the intravascular automatic drug delivery device of the embodiment provided in FIG. 1;
FIG. 3 illustrates a schematic diagram of the connection of the needle rotation mechanism to the injection assembly of the embodiment provided in FIG. 1;
FIG. 4 shows a schematic view of a portion of the construction of the injection assembly of the embodiment provided in FIG. 1;
FIG. 5 illustrates a schematic connection of the needle rotation mechanism, the injection assembly and the needle bending mechanism of the embodiment provided in FIG. 1 at a first view angle;
FIG. 6 illustrates a schematic view of the connection of the needle rotation mechanism, the injection assembly and the needle bending mechanism of the embodiment provided in FIG. 1 at a second view angle;
FIG. 7 shows a schematic view of the configuration of the first coupling or the second coupling of the needle rotation mechanism of the embodiment provided in FIG. 1;
FIG. 8 is a schematic view showing the connection of the needle delivery mechanism and the injection assembly of the embodiment provided in FIG. 1;
FIG. 9 shows a schematic view of the configuration of a first bearing housing in the needle delivery mechanism of the embodiment provided in FIG. 1;
FIG. 10 is a schematic view showing the structure of a second bearing in the needle delivery mechanism of the embodiment provided in FIG. 1;
fig. 11 is a schematic view showing the structure of the drug solution pushing mechanism of the embodiment provided in fig. 1;
FIG. 12 is a schematic view showing the structure of a pushing assembly in the pushing mechanism according to the embodiment shown in FIG. 1;
FIG. 13 is a schematic view showing the structure of a push rod joint in the pushing mechanism of the embodiment of FIG. 1;
fig. 14 is a schematic view showing the structure of a second three-way valve and an air pressure sensor in the pushing mechanism for pushing medical fluid according to the embodiment provided in fig. 1.
Wherein, the correspondence between the reference numerals and the component names in fig. 1 to 14 is:
1-a base; 11-a support plate; 111-a third support element; 12-a support shell; 2-needle bending mechanism; 21-a first drive motor; 22-a third coupling; 23-output shaft; 24-driving wires; 25-a turntable; 26-continuum part; 3-a needle rotation mechanism; 31-a piezoelectric driving motor; 32-a first coupling; 38-an injection needle outer sleeve; 4-a needle delivery mechanism; 41-fixing the bottom plate; 42-a second drive motor; 43-an adapter member; 44-a bearing housing assembly; 441-a first bearing housing; 442-a second bearing mount; 443-a first sleeve; 444-a second sleeve; 5-a liquid medicine pushing mechanism; 51-a first three-way valve; 52-a second three-way valve; 53-a drug injection hose; 54-pushing assembly; 541-a drug-injection sleeve; 542-rubber piston; 543-sealing ring; 544-push rod; 545-a push rod joint; 55-servo electric bars; 56-an air pressure sensor; 57-pressure sensor; 6-an injection assembly; 61-an injection needle; 62-syringe; 7-a support member; 71-a first support element; 711-supporting ring; 72-a second support element; 721-fixation element; 722-a fixed plate; 723-a fixed rod.
Detailed Description
In order that the above-recited objects, features and advantages of the present application will be more clearly understood, a more particular description of the application will be rendered by reference to the appended drawings and appended detailed description. It should be noted that, without conflict, the embodiments of the present application and features in the embodiments may be combined with each other.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application, however, the present application may be practiced in other ways than those described herein, and therefore the scope of the present application is not limited to the specific embodiments disclosed below.
Retinal Vein Occlusion (RVO) is a worldwide important cause of vision decline in the elderly, and it manifests as thrombus formation in the center of retinal veins or branch vessels, resulting in serious vision loss and even blindness. In order to ensure the safety and accuracy of Retinal Vein Occlusion (RVO) procedures, it is important to provide an intravascular automatic drug delivery device that assists the surgeon in the procedure.
The application provides intravascular automatic medicine injection equipment, which aims to at least solve the problem that an injection needle 61 can be stably injected in a retinal blood vessel, improve the positioning precision of the injection needle 61 during intravascular puncture, and detect the puncture force of the injection needle 61 in real time so that medicine can be stably pushed at a specified speed.
The present application provides an intravascular automatic drug injection device, as shown in fig. 1 and 2, comprising: a needle bending mechanism 2, a needle rotation mechanism 3, a needle delivery mechanism 4 and an injection assembly 6. The injection assembly 6 includes a needle 61 and a syringe 62, and the needle 61 is connected to one end of the syringe 62. The liquid medicine pushing mechanism 5 is connected with the injection assembly 6, and the liquid medicine pushing mechanism 5 is communicated with the other end of the injection tube 62. The injection needle rotating mechanism 3 is connected with the injection assembly 6, the injection needle rotating mechanism 3 comprises an injection needle outer sleeve 38 and a rotating assembly, the injection needle rotating mechanism 3 is wrapped outside the injection tube 62, and the rotating assembly drives the injection assembly 6 to rotate through the injection needle outer sleeve 38. The needle bending mechanism 2 is disposed on the needle rotating mechanism 3, and the needle bending mechanism 2 is connected to an end portion of the needle outer sleeve 38 near the needle 61 to drive the needle 61 to bend. The injection needle delivery mechanism 4 clamps the injection assembly 6 to drive the injection assembly 6 to move.
Specifically, the medical fluid pushing mechanism 5 stores medical fluid, and the medical fluid pushing mechanism 5 can push the medical fluid through the syringe 62 to the injection needle 61 at a predetermined speed until it is pushed into the patient. The injection assembly 6 is driven to rotate by the injection needle rotating mechanism 3, and the injection assembly 6 is driven to move forwards or backwards by the injection needle delivering mechanism 4, so that the injection needle 61 can be inserted into a blood vessel with reasonable force. The needle bending mechanism 2 is connected to the end of the needle outer sleeve 38 near the needle 61 to bend the needle 61 so that the needle 61 can be accurately inserted into the blood vessel of the patient.
In some alternative embodiments, as shown in fig. 1 and 2, the intravascular automatic injection device further includes a base 1, and the needle rotating mechanism 3, the needle delivery mechanism 4, and the drug solution pushing mechanism 5 are disposed in this order in the length direction of the base 1.
Specifically, the length of the injection assembly 6 extends in the same direction as the length of the base 1. The needle bending mechanism 2, the needle rotating mechanism 3, the needle delivery mechanism 4, and the drug solution pushing mechanism 5 are connected to the injection unit 6 in this order in the longitudinal direction of the injection unit 6.
Further, the base 1 includes a support case 12 and a support plate 11, the support case 12 and the injection needle rotating mechanism 3 being provided to the support plate 11; the needle rotating mechanism 3, the needle bending mechanism 2, and the needle delivery mechanism 4 are provided inside the support case 12, one end of the needle 61 and the syringe 62 is located outside the support case 12, and the liquid pushing mechanism 5 penetrates the support case 12 and is connected to the other end of the syringe 62.
Specifically, as shown in fig. 2, the supporting case 12 is provided with a housing space, the needle rotating mechanism 3 and the needle delivering mechanism 4 are fixed to the supporting case 12, the needle 61 is provided outside the supporting case 12, at least a part of an end portion of the syringe 62 connected to the needle 61 is provided outside the supporting case 12, a part of the syringe 62 inside the supporting case 12 is connected to the needle rotating mechanism 3 and the needle delivering mechanism 4 in order, and the drug solution pushing mechanism 5 passes through the supporting case 12 to be connected to an end of the syringe 62 remote from the needle 61.
Further, as shown in fig. 1 and 2, the support plate 11 is provided with a plurality of third support elements 111, optionally, the plurality of third support elements 111 are sequentially disposed in the length direction of the support plate 11, optionally, the support plate 11 includes four third support elements 111, a preset distance is disposed between each of the third support elements 111, and the four third support elements 111 are sequentially a first third support element 111, a second third support element 111, a third support element 111, and a fourth third support element 111 in the length direction of the support plate 11. The support shell 12 is arranged between the first and second third support elements 111, the support shell 12 being connected to the first and second third support elements 111, respectively, and optionally the support shell 12 being bolted to the first and second third support elements 111, respectively. The medical fluid pushing mechanism 5 is supported by a third supporting element 111 and a fourth third supporting element 111, and optionally, the medical fluid pushing mechanism 5 is connected with the third supporting element 111 and the fourth third supporting element 111 through bolts.
In some alternative embodiments, as shown in fig. 11, the medical fluid pushing mechanism 5 includes a first three-way valve 51, a second three-way valve 52, a drug injection hose 53, a pushing assembly 54, a servo motor lever 55, a pneumatic sensor 56, and a pressure sensor 57; the first three-way valve 51, the medicine injection hose 53, the pushing component 54 and the servo motor lever 55 are sequentially connected; the first three-way valve 51 is connected with the injection tube 62 and the injection hose 53 respectively; the second three-way valve 52 is sleeved on the pushing component 54, and the air pressure sensor 56 is arranged on the second three-way valve 52; the pressure sensor 57 is provided to the servo motor lever 55.
Specifically, as shown in fig. 11, the first three-way valve 51 includes three ports, one of which is connected to the syringe 62 and the other of which is connected to the medicine container containing medicine with the medicine-injecting hose 53. The pushing component 54 is provided with a second three-way valve 52, and the second three-way valve 52 is provided with a gas pressure sensor 56, wherein the gas pressure sensor 56 is used for sensing the real-time gas pressure and preventing the excessive injection flow rate of the medicine.
In some alternative embodiments, as shown in fig. 11, 12, 13, and 14, the push assembly 54 includes a drug-injection sleeve 541 and a compression assembly that is slidable within the drug-injection sleeve 541; the extrusion assembly comprises a rubber piston 542, a sealing ring 543, a push rod 544 and a push rod joint 545, wherein the rubber piston 542, the push rod 544 and the push rod joint 545 are sequentially connected, and the sealing ring 543 is sleeved outside the rubber piston 542.
Specifically, servo cylinder 57 is connected to push rod fitting 545. The end of the push rod 544 is provided with a snap spring for limiting movement of the push rod 544. A gas-liquid mixture such as silicone oil is arranged between the push rod 544 and the rubber piston 542, the servo cylinder 57 pushes the push rod 544 forwards through the push rod connector 545, the gas-liquid mixture such as silicone oil can play a buffering effect, the push rod 544 pushes the rubber piston 542 to move forwards, the rubber piston 542 presses air, then the liquid medicine in the medicine container is pushed to move in the injection tube 62, and the liquid medicine is injected through the injection needle 61, so that automatic medicine injection is completed.
In some alternative embodiments, as shown in fig. 3, 5, 6 and 7, the rotating assembly includes a piezoelectric drive motor 31, a first coupling 32 and a second coupling, the piezoelectric drive motor 31 being coupled to the first coupling 32 and the second coupling, respectively, the first coupling 32 being coupled to the syringe outer sleeve 38, and the second coupling being coupled to the needle bending mechanism 2.
Specifically, in the longitudinal direction of the syringe 62, the first coupling 32 and the second coupling are disposed back-to-back on the piezoelectric driving motor 31, the syringe outer sleeve 38 is sleeved outside the syringe 62, the syringe outer sleeve 38 penetrates through the first coupling 32, the piezoelectric driving motor 31 and the second coupling, the piezoelectric driving motor 31 is connected with the syringe outer sleeve 38 through the first coupling 32, and the piezoelectric driving motor 31 drives the syringe outer sleeve 38 and the syringe 62 to rotate.
In some alternative embodiments, as shown in fig. 5, the needle bending mechanism 2 includes a first drive motor 21, a third coupling 22, an output shaft 23, a drive wire 24, a turntable 25, and a continuum member 26; the second coupling is connected with the turntable 25, the first drive motor 21 is arranged on the turntable 25, the first drive motor 21 is connected with the third coupling 22, the output shaft 23 is connected with the drive wire 24, and the drive wire 24 passes through the outer sleeve 38 of the injection tube and is connected with the continuous body part 26.
Specifically, the piezoelectric driving motor 31 drives the turntable 25 to rotate through the second coupling, the first driving motor 21 is connected with the output shaft 23 through the third coupling 22, the output shaft 23 is connected with the driving wire 24, and the driving wire 24 passes through the small hole of the outer sleeve 38 of the injection tube and ensures the shape to be fixed in the outer sleeve 38 of the injection tube. The first driving motor 21 is arranged on the turntable 25, when the turntable 25 rotates, the first driving motor 21 can rotate along with the turntable 25, and the first driving motor 21 can change the position and the angle in the rotating process, so that the length of the driving wire 24 can be influenced, the extension and the contraction of the driving wire 24 are driven, the length of the driving wire 24 can change to drive the continuous body part 26 to bend, the injection needle 61 close to the continuous body part 26 is bent, the injection needle can be accurately inserted into a blood vessel of a patient, and the positioning precision of the injection needle 61 during intravascular puncture is improved. A plurality of fbg gratings are mounted on the distal end of the injection tube 62 to detect the minute penetration force of the injection needle 61. Optionally, three fbg gratings are mounted at the end of the drug delivery tube 62.
In some alternative embodiments, the injector further comprises a support member 7, wherein one end of the support member 7 is disposed on the housing of the piezoelectric driving motor 31, and the other end of the support member 7 is connected to the syringe external sleeve 38 through a first bearing.
Specifically, the support part 7 includes a first support member 71 and a second support member 72, one end of the first support member 71 is provided with a support ring 711, the other end of the first support member 71 is connected to one end of the second support member 72, one end of the second support member 72 remote from the first support member 71 is provided with a fixing member 721, the fixing member 721 includes a fixing plate 722 and a fixing rod 723, the fixing plate 722 is provided with a plurality of fixing rods 723, and the second support member 72 is connected to the housing of the piezoelectric driving motor 31 through the fixing member 721.
Further, the second support member 72 is connected to the fixing plate 722, and the housing of the piezoelectric driving motor 31 is provided with a plurality of fixing holes, and the respective fixing rods 723 of the fixing members 721 are respectively abutted with the respective fixing holes, so that the support part 7 is fixed to the housing of the piezoelectric driving motor 31. The syringe 62 of the injection assembly 6 penetrates the support ring 711 so that the support member 7 supports the injection assembly 6.
In some alternative embodiments, as shown in fig. 8, 9 and 10, the delivery needle delivery mechanism 4 includes a fixed base plate 41, a second drive motor 42, an adapter member 43, and a bearing housing assembly 44, the fixed base plate 41, the second drive motor 42, the adapter member 43, and the bearing housing assembly 44 being stacked, with the syringe 62 extending through the bearing housing assembly 44.
Specifically, the second driving motor 42 is a piezoelectric linear driving motor, the outer sleeve 38 of the injection needle passes through the piezoelectric rotary driving motor, the motor shaft is hollow, the injection tube 62 extends out of the outer sleeve 38 of the injection needle and is fixed on the two bearing seat assemblies 44, the injection tube 62 is prevented from rotating to generate torque, the bearing seat assemblies 44 clamp the injection tube 62, the bearing seat assemblies 44 are fixed on the adapting component 43 through screws, the adapting component 43 is fixed with a linear driving platform of the piezoelectric linear driving motor through screws, and the piezoelectric linear driving motor is connected with the fixed bottom plate 41 through screws. When the piezoelectric linear driving motor works, the linear driving platform of the piezoelectric linear driving motor moves forwards to drive the switching part 43 and the bearing seat assembly 44 to move forwards, so that the forward pushing of the medicine injection tube 62 is realized, and the forward delivery of the injection needle 61 is completed. The adapter member 43 is an adapter plate.
In some alternative embodiments, as shown in fig. 8, 9 and 10, the bearing housing assembly 44 includes a first bearing housing 441 and a second bearing housing 442, the first bearing housing 441 and the second bearing housing 442 being arranged in a length direction of the syringe 62, the first bearing housing 441 being provided with a first sleeve 443, and the second bearing housing 442 being provided with a second sleeve 444.
Specifically, the needle outer sleeve 38 passes through a piezoelectric rotary drive motor, and the syringe 62 extends out of the needle outer sleeve 38 and is secured to the two bearing blocks 44 to prevent torque from being generated by rotation of the syringe 62. The first bearing seat 441 and the second bearing seat 442 clamp the medicine injection tube 62, and are fixed on the adapter plate 43 by screws, the adapter plate 43 is fixed with a linear driving platform of a piezoelectric linear driving motor by screws, and the piezoelectric linear driving motor is connected with the fixed bottom plate 41 by screws. When the piezoelectric linear driving motor works, the linear driving platform moves forwards to drive the adapter plate 43, the first bearing seat 441 and the second bearing seat 442 to move forwards, so that the medicine injection tube 62 is pushed forwards, and the injection needle 61 is delivered forwards.
In the present application, the term "plurality" means at least two or more, unless explicitly defined otherwise. The terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; "coupled" may be directly coupled or indirectly coupled through intermediaries. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art according to the specific circumstances.
In the description of the present specification, the terms "one embodiment," "some embodiments," "particular embodiments," and the like, mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present application. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics may be combined in any suitable manner in any one or more embodiments or examples.
The above is only a preferred embodiment of the present application, and is not intended to limit the present application, but various modifications and variations can be made to the present application by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the protection scope of the present application.

Claims (10)

1. An intravascular automatic drug delivery device, comprising:
an injection assembly (6) comprising an injection needle (61) and an injection tube (62), wherein the injection needle (61) is connected with one end of the injection tube (62);
the liquid medicine pushing mechanism (5) is connected with the injection assembly (6) and is communicated with the other end of the injection tube (62);
the injection needle rotating mechanism (3) is connected with the injection assembly (6) and comprises an injection needle outer sleeve (38) and a rotating assembly, the injection needle rotating mechanism (3) is wrapped outside the injection tube (62), and the rotating assembly drives the injection assembly (6) to rotate through the injection needle outer sleeve (38);
the injection needle bending mechanism (2) is arranged on the injection needle rotating mechanism (3) and is connected with the end part, close to the injection needle (61), of the injection needle outer sleeve (38) so as to drive the injection needle (61) to bend;
and the injection needle delivery mechanism (4) clamps the injection assembly (6) and drives the injection assembly (6) to move.
2. The intravascular automatic drug delivery device according to claim 1, further comprising a base (1), wherein the needle rotating mechanism (3), the needle delivery mechanism (4) and the drug solution pushing mechanism (5) are sequentially disposed in a longitudinal direction of the base (1).
3. The intravascular automatic drug delivery device according to claim 2, wherein the base (1) comprises a support housing (12) and a support plate (11), the support housing (12) and the injection needle rotation mechanism (3) being provided to the support plate (11);
the injection needle rotating mechanism (3), the injection needle bending mechanism (2) and the injection needle delivery mechanism (4) are arranged in the supporting shell (12), one ends of the injection needle (61) and the injection tube (62) are located outside the supporting shell (12), and the liquid medicine pushing mechanism (5) penetrates through the supporting shell (12) and is connected with the other end of the injection tube (62).
4. An intravascular automatic drug delivery device according to claim 3, wherein the drug solution pushing mechanism (5) comprises a first three-way valve (51), a second three-way valve (52), a drug delivery hose (53), a pushing assembly (54), a servo motor lever (55), a barometric sensor (56) and a pressure sensor (57);
the first three-way valve (51), the medicine injection hose (53), the pushing assembly (54) and the servo motor lever (55) are sequentially connected;
the first three-way valve (51) is respectively connected with the injection tube (53) and the medicine injection hose (53);
the second three-way valve (52) is sleeved on the pushing assembly (54), and the air pressure sensor (56) is arranged on the second three-way valve (52);
the pressure sensor (57) is provided to the servo lever (55).
5. An intravascular automatic drug delivery device according to claim 4, wherein the pushing assembly (54) comprises a drug delivery sleeve (541) and a compression assembly, the compression assembly being slidable within the drug delivery sleeve (541);
the extrusion assembly comprises a rubber piston (542), a sealing ring (543), a push rod (544) and a push rod joint (545), wherein the rubber piston (542) is sequentially connected with the push rod (544) and the push rod joint (545), and the sealing ring (543) is sleeved outside the rubber piston (542).
6. The intravascular automatic drug delivery device according to claim 1, wherein the rotating assembly comprises a piezoelectric drive motor (31), a first coupling (32) and a second coupling, the piezoelectric drive motor (31) is connected with the first coupling (32) and the second coupling respectively, the first coupling (32) is connected with the syringe outer sleeve (38), and the second coupling is connected with the injection needle bending mechanism (2).
7. The intravascular automatic drug delivery device of claim 6, wherein the needle bending mechanism (2) comprises a first drive motor (21), a third coupling (22), an output shaft (23), a drive wire (24), a turntable (25) and a continuum member (26); the second shaft coupling is connected with the rotary table (25), the first driving motor (21) is arranged on the rotary table (25), the first driving motor (21) is connected with the third shaft coupling (22), the output shaft (23) is connected with the driving wire (24), and the driving wire (24) penetrates through the outer sleeve (38) of the injection tube and is connected with the continuous body part (26).
8. The intravascular automatic drug delivery device according to claim 7, further comprising a support member (7), wherein one end of the support member (7) is disposed on a housing of the piezoelectric driving motor (31), and the other end of the support member (7) is connected to the syringe external sleeve (38) through a first bearing.
9. The delivery needle delivery mechanism (4) according to claim 7, comprising a fixed base plate (41), a second drive motor (42), an adapter member (43) and a bearing housing assembly (44), wherein the fixed base plate (41), the second drive motor (42), the adapter member (43) and the bearing housing assembly (44) are arranged in a stack, and wherein the injection tube (62) extends through the bearing housing assembly (44).
10. The bearing housing assembly (44) according to claim 9, characterized in that the bearing housing assembly (44) comprises a first bearing housing (441) and a second bearing housing (442), the first bearing housing (441) and the second bearing housing (442) being arranged in the length direction of the injection tube (62), the first bearing housing (441) being provided with a first sleeve (443), the second bearing housing (442) being provided with a second sleeve (444).
CN202310459977.9A 2023-04-25 2023-04-25 Automatic medicine injection equipment in blood vessel Pending CN116616994A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310459977.9A CN116616994A (en) 2023-04-25 2023-04-25 Automatic medicine injection equipment in blood vessel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310459977.9A CN116616994A (en) 2023-04-25 2023-04-25 Automatic medicine injection equipment in blood vessel

Publications (1)

Publication Number Publication Date
CN116616994A true CN116616994A (en) 2023-08-22

Family

ID=87596385

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202310459977.9A Pending CN116616994A (en) 2023-04-25 2023-04-25 Automatic medicine injection equipment in blood vessel

Country Status (1)

Country Link
CN (1) CN116616994A (en)

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