CN116568321A - 用于治疗神经变性疾病的靶向髓鞘少突胶质细胞糖蛋白(mog)的基于car-treg的疗法 - Google Patents

用于治疗神经变性疾病的靶向髓鞘少突胶质细胞糖蛋白(mog)的基于car-treg的疗法 Download PDF

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Publication number
CN116568321A
CN116568321A CN202180059182.8A CN202180059182A CN116568321A CN 116568321 A CN116568321 A CN 116568321A CN 202180059182 A CN202180059182 A CN 202180059182A CN 116568321 A CN116568321 A CN 116568321A
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protein
cells
disease
glial
treg
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CN202180059182.8A
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Chinese (zh)
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L·B·沃特金
P·G·阿什顿-里卡特
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Az Treatment Co ltd
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Az Treatment Co ltd
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Priority to CN202411201412.1A priority Critical patent/CN119410588A/zh
Publication of CN116568321A publication Critical patent/CN116568321A/zh
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C12N5/0634—Cells from the blood or the immune system
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CN202180059182.8A 2020-05-28 2021-05-28 用于治疗神经变性疾病的靶向髓鞘少突胶质细胞糖蛋白(mog)的基于car-treg的疗法 Pending CN116568321A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202411201412.1A CN119410588A (zh) 2020-05-28 2021-05-28 用于治疗神经变性疾病的靶向髓鞘少突胶质细胞糖蛋白(mog)的基于car-treg的疗法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063031261P 2020-05-28 2020-05-28
US63/031,261 2020-05-28
PCT/US2021/034968 WO2021243275A2 (en) 2020-05-28 2021-05-28 Car-treg-based therapies for treating neurgdegenerative diseases

Related Child Applications (1)

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CN202411201412.1A Division CN119410588A (zh) 2020-05-28 2021-05-28 用于治疗神经变性疾病的靶向髓鞘少突胶质细胞糖蛋白(mog)的基于car-treg的疗法

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CN116568321A true CN116568321A (zh) 2023-08-08

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CN202180059182.8A Pending CN116568321A (zh) 2020-05-28 2021-05-28 用于治疗神经变性疾病的靶向髓鞘少突胶质细胞糖蛋白(mog)的基于car-treg的疗法
CN202411201412.1A Pending CN119410588A (zh) 2020-05-28 2021-05-28 用于治疗神经变性疾病的靶向髓鞘少突胶质细胞糖蛋白(mog)的基于car-treg的疗法

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US (1) US20230210899A1 (https=)
EP (1) EP4157877A2 (https=)
JP (1) JP2023531378A (https=)
CN (2) CN116568321A (https=)
IL (1) IL298501A (https=)
WO (1) WO2021243275A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112840019A (zh) * 2018-08-14 2021-05-25 Sotio有限责任公司 与调节克雷布斯循环的反式代谢分子组合的嵌合抗原受体多肽及其治疗用途

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3773629A4 (en) 2018-03-27 2022-01-19 AZTherapies, Inc. CAR-TREG-BASED THERAPIES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
WO2010141801A2 (en) 2009-06-05 2010-12-09 Cellular Dynamics International, Inc. Reprogramming t cells and hematophietic cells
EP3773629A4 (en) * 2018-03-27 2022-01-19 AZTherapies, Inc. CAR-TREG-BASED THERAPIES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
JP7817159B2 (ja) * 2019-11-08 2026-02-18 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 炎症状態及び変性疾患を処置するために操作された間葉系幹細胞を使用する方法及び材料

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112840019A (zh) * 2018-08-14 2021-05-25 Sotio有限责任公司 与调节克雷布斯循环的反式代谢分子组合的嵌合抗原受体多肽及其治疗用途
CN112840019B (zh) * 2018-08-14 2025-07-04 Sotio有限责任公司 与调节克雷布斯循环的反式代谢分子组合的嵌合抗原受体多肽及其治疗用途

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CN119410588A (zh) 2025-02-11
US20230210899A1 (en) 2023-07-06
WO2021243275A2 (en) 2021-12-02
IL298501A (en) 2023-01-01
EP4157877A2 (en) 2023-04-05
JP2023531378A (ja) 2023-07-24
WO2021243275A3 (en) 2022-02-17

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