CN116549104A - Laser injector device and manufacturing method of laser injector needle thereof - Google Patents
Laser injector device and manufacturing method of laser injector needle thereof Download PDFInfo
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- CN116549104A CN116549104A CN202310228205.4A CN202310228205A CN116549104A CN 116549104 A CN116549104 A CN 116549104A CN 202310228205 A CN202310228205 A CN 202310228205A CN 116549104 A CN116549104 A CN 116549104A
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- 229910021421 monocrystalline silicon Inorganic materials 0.000 claims description 10
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 9
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- 239000000853 adhesive Substances 0.000 claims 1
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- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 10
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
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- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C25/00—Surface treatment of fibres or filaments made from glass, minerals or slags
- C03C25/10—Coating
- C03C25/104—Coating to obtain optical fibres
- C03C25/1065—Multiple coatings
- C03C25/1068—Inorganic coatings
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J5/00—Adhesive processes in general; Adhesive processes not provided for elsewhere, e.g. relating to primers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B2018/2205—Characteristics of fibres
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B2018/2255—Optical elements at the distal end of probe tips
- A61B2018/2266—Optical elements at the distal end of probe tips with a lens, e.g. ball tipped
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- Health & Medical Sciences (AREA)
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Abstract
The invention relates to a laser injector device and a method for manufacturing a laser injector needle thereof, which comprises a laser injector and a laser needle connected with the output end of the laser injector; the laser injector comprises a linear motor and a laser, wherein the linear motor is used for driving the laser to move, and the laser is connected to a rotor straight shaft of the linear motor; the laser needle comprises a needle tail, a needle tube, an optical fiber and AB glue, wherein the needle tail is connected to a laser of the laser injector; the laser emits the required laser, the beam collimation is regulated by the beam expander, the laser is focused by the focusing lens and finally coupled into the optical fiber of the laser needle, the laser is released by the laser needle and acts on the central part of the malignant tumor, and the variant cells are killed by the high temperature generated by the laser. The invention emits the needed laser through the laser, then releases the laser through the laser needle head and acts on the central part of the malignant tumor, and kills the variant cells by utilizing the high temperature generated by the laser.
Description
Technical Field
The invention relates to a laser injector device and a manufacturing method of a laser injector needle head thereof.
Background
Medically, cancer refers to malignant tumors originating in epithelial tissue, the most common of which. Correspondingly, malignant tumors originating from mesenchymal tissue are collectively referred to as sarcomas. There are a few malignant tumors which are not named according to the above principles, such as nephroblastoma, malignant teratoma, etc. The term "cancer" is generally used to refer to all malignant tumors.
Tumors are novel organisms formed by abnormal proliferation and differentiation caused by the fact that cells of local tissues lose normal regulation on the gene level of the organisms under the action of various tumorigenic factors. Once a new organism is formed, it does not stop growing due to the elimination of the cause, and its growth is not physiologically regulated by the normal organism, but destroys normal tissues and organs, which is particularly evident in malignant tumors. Compared with benign tumor, malignant tumor has fast growth speed, is infiltrative, is easy to generate bleeding, necrosis, ulcer and the like, and often has distant metastasis, thus causing emaciation, weakness, anemia, inappetence, fever, serious organ function damage and the like of human body, and finally causing death of patients.
At present, surgery treatment, chemotherapy, radiation treatment, targeted treatment, immunotherapy and traditional Chinese medicine treatment are generally adopted for medical treatment of malignant tumors, wherein the targeted treatment is to design corresponding instruction drugs, the drugs are injected into cancerogenic sites in human bodies to combine and send actions, so that cancer cells die, but the treatment period is long, the human bodies receive the drugs for a long time and are easy to generate immunity to the drugs, so that the treatment is influenced, the targeted instruction equipment cannot accurately inject pillows into the targeted drugs, inconvenience is brought to the treatment, and no equipment for killing cancer cells by utilizing high temperature generated by laser at the central part of the malignant tumors is available in China.
Disclosure of Invention
In view of the foregoing, it is an object of the present invention to provide a laser injector device and a method for manufacturing a laser injector needle thereof, which solve at least one of the above problems.
The technical scheme adopted for realizing the purpose of the invention is as follows: a laser injector device comprises a laser injector and a laser needle connected with the output end of the laser injector;
the laser injector comprises a linear motor and a laser, wherein the linear motor is used for driving the laser to move, and the laser is connected to a rotor straight shaft of the linear motor;
the laser needle comprises a needle tail, a needle tube, an optical fiber and AB glue, wherein the needle tail is connected to a laser of the laser injector, a cavity is formed in the needle tail, the needle tube is fixedly connected to the needle tail and is communicated with the cavity of the needle tail, the front end of the needle tube is the tip of a tangential plane, the optical fiber is positioned in the laser needle, one end of the optical fiber is positioned at the needle tail and is connected with the output end of the laser, the other end of the optical fiber is positioned at the tip of the needle tube, and the AB glue is filled in a gap between the cavity of the needle tail and the optical fiber;
the laser emits the required laser, the beam collimation is regulated by the beam expander, the laser is focused by the focusing lens and finally coupled into the optical fiber of the laser needle, the laser is released by the laser needle and acts on the central part of the malignant tumor, and the variant cells are killed by the high temperature generated by the laser.
Further, the laser injector also comprises a manipulator for controlling the position of the linear motor, and the manipulator is connected with the stator part of the linear motor.
Further, the laser comprises a laser host, a laser generator cable, a power supply line, a signal line and a host control module; the laser, the laser transmitter cable, the power supply line and the signal line are respectively and electrically connected with the host control module.
Further, the host control module comprises a micro controller, a control panel module and a display, wherein the host control module is used for displaying and controlling a laser switch and laser power conversion, under the control of the micro controller, the host control module can be started or switched to different laser powers through an operating system on the control panel module, and the display on the control panel module displays corresponding numbers of power and action time during laser output.
Further, the host control module is further connected with the linear motor and the mechanical torch respectively, under the control of the host control module, the linear motor is started through the control panel module, and the movement direction of the linear motor rotor part is changed according to requirements, so that the positions of the laser and the laser needle are driven through the linear motor rotor part, and the tip of the laser needle is enabled to act on the target.
Further, the manipulator starts the manipulator through the control panel module under the control of the host control module and operates the movement of the machinery, so that the manipulator drives the stator part of the linear motor to move, and the stator part of the linear motor drives the laser and the laser needle to move, so that the position of the laser needle is changed.
Further, the laser adopts a laser with adjustable power.
Further, the needle tube is prepared according to different parts of the injection heart, the alimentary canal, the body surface and the like: corresponding calibers of 0.7mm, 1.0mm, 2.0mm, etc.
A manufacturing method of a laser syringe needle comprises an electroplating method for preparing the laser syringe needle;
the electroplating method comprises the following steps:
step 1: drawing monocrystalline silicon into an optical fiber shape required by a laser needle;
step 2: silver plating technology is adopted to integrally silver the surface of the optical fiber to form silver plated optical fiber;
step 3: plating a layer of thin copper on the surface of the silver-plated optical fiber by utilizing an electroplating technology, so as to form a copper-plated optical fiber;
the method comprises the following steps: plating a layer of thin nickel on the surface of the copper-plated optical fiber by utilizing an electroplating technology to form a nickel-plated optical fiber;
step 5: plating a layer of thin gold on the surface of the nickel-plated optical fiber by utilizing an electroplating technology to form a gold-plated optical fiber;
step 6: forming a needle tube of a laser needle at the front end of the gold-plated optical fiber by adopting a grinding and polishing technology;
step 7: manufacturing the tail part of the laser needle head at the tail part of the laser needle head by adopting a laser coupling technology;
step 8: grinding the front end of a needle tube of the preliminary laser needle into a tip meeting the requirements by adopting an optical fiber surface grinding and polishing technology;
step 9: adopting an optical fiber surface grinding and polishing technology to treat the tail end of the preliminary laser needle head into an end surface coupled with a laser;
step 10: the cross-sectional images of the front and rear ends of the laser needle are detected by a microscope to determine that the laser needle is made to meet the required requirements.
A manufacturing method of a laser syringe needle comprises an adhesion method for preparing the laser needle;
the bonding method comprises the following steps:
step 1: drawing a corresponding drawing according to the required laser needle, and manufacturing the needle tail and the needle tube of the corresponding laser needle according to the drawing;
step 2: drawing monocrystalline silicon into optical fibers required by a laser needle by using a Czochralski monocrystalline silicon technology according to a drawing;
step 3: the special AB glue for the optical fiber is used for bonding the optical fiber in the tail part of the laser needle head and the needle tube to form a preliminary laser needle head;
step 4: grinding and polishing the surface of the optical fiber, and polishing the front end of the preliminary needle tube into a tip meeting the requirements;
step 5: grinding and polishing the surface of an optical fiber, and processing the tail part of the needle head of the preliminary laser needle head into an end surface coupled with a laser;
step 6: and detecting the end face patterns of the tip and the tail of the laser needle by using a microscope to determine the compliance.
The invention has the beneficial effects that:
1. the laser needle is driven by the linear motor to act on the central part of the tumor in the human body, so that the situation that the laser needle cannot act on the tumor due to the deviation of the position of the laser needle is avoided;
2. the laser emits the required laser, the beam collimation is regulated by the beam expander, the laser is focused by the focusing lens and finally coupled into the optical fiber of the laser needle, the laser is released by the laser needle and acts on the central part of the malignant tumor, and the variant cells are killed by the high temperature generated by the laser, so that the effect of treating the malignant tumor is achieved;
3. the movement of the manipulator is operated through the control panel module, so that the position and the angle of the laser needle head and the tumor are adjusted, and the center position of the tumor is accurately injected by the laser needle head.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present invention.
Fig. 2 is a schematic structural diagram of a manipulator connected with a linear motor according to the present invention.
Fig. 3 is a partial cross-sectional view of a laser needle.
Fig. 4 is a circuit diagram of the present invention.
In the figure, a 1-linear motor, a 2-linear motor stator part, a 3-linear motor rotor straight shaft, a 4-laser, a 5-laser needle head, a 6-manipulator, a 7-optical fiber, an 8-needle tube, a 9-tip, a 10-AB glue and a 11-needle head tail part are arranged.
Detailed Description
The invention will be further described with reference to the drawings and the specific examples.
Fig. 1, 2, 3 and 4 schematically illustrate a laser injector device and a method for manufacturing a laser injector needle according to an embodiment of the present invention.
As shown in fig. 1, 2, 3 and 4, a laser injector device is characterized in that: the laser needle comprises a laser injector and a laser needle connected to the output end of the laser injector;
the laser injector comprises a linear motor and a laser, wherein the linear motor is used for driving the laser to move, and the laser is connected to a rotor straight shaft of the linear motor;
the laser needle comprises a needle tail, a needle tube, an optical fiber and AB glue, wherein the needle tail is connected to a laser of the laser injector, a cavity is formed in the needle tail, the needle tube is fixedly connected to the needle tail and is communicated with the cavity of the needle tail, the front end of the needle tube is the tip of a tangential plane, the optical fiber is positioned in the laser needle, one end of the optical fiber is positioned at the needle tail and is connected with the output end of the laser, the other end of the optical fiber is positioned at the tip of the needle tube, and the AB glue is filled in a gap between the cavity of the needle tail and the optical fiber;
the laser emits the required laser, the beam collimation is regulated by the beam expander, the laser is focused by the focusing lens and finally coupled into the optical fiber of the laser needle, the laser is released by the laser needle and acts on the central part of the malignant tumor, and the variant cells are killed by the high temperature generated by the laser.
As shown in fig. 1, 2 and 3, the AB glue is used to fasten the optical fiber to the tail of the needle, so as to avoid unstable connection between the laser needle and the laser injector caused by loosening of the optical fiber, and thus affect the transmission of laser.
As shown in fig. 1, 2 and 3, the front end of the needle tube is provided with a sharp end with a tangential plane, so that the needle tube is convenient to be injected into the tissues of a human body.
As shown in fig. 1, 2 and 3, the needle tube is used for protecting the optical fiber from damage.
As shown in fig. 1, 2 and 3, the laser injector generates laser light and is coupled to an optical fiber of a laser needle connected to an output end of the laser injector.
As shown in fig. 1 and 2, the laser injector further comprises a manipulator for controlling the position of the linear motor, and the manipulator is connected with the stator part of the linear motor.
As shown in fig. 1, 2, 3 and 4, the laser includes a laser host, a laser generator cable, a power supply line, a signal line and a host control module; the laser, the laser transmitter cable, the power supply line and the signal line are respectively and electrically connected with the host control module.
As shown in fig. 1, 2, 3 and 4, the host control module includes a micro controller, a control panel module, a display and the like, and the host control module is used for displaying and controlling a laser switch, laser power conversion and the like, and under the control of the micro controller, the host control module can be started or switched to different laser powers through an operating system on the control panel module, and the power and the action time during laser output display corresponding numbers on the display on the control panel module.
As shown in fig. 1, 2, 3 and 4, the host control module is further connected with the linear motor and the mechanical flashlight respectively, and under the control of the micro controller, the linear motor is started by the control panel module, and the movement direction (such as extension or contraction) of the linear motor rotor part is changed according to the requirement, so that the positions of the laser and the laser needle are driven by the linear motor rotor part, and the tip of the laser needle acts on the target.
As shown in fig. 1, fig. 2, fig. 3 and fig. 4, the manipulator is controlled by the host control module, the manipulator is started by the control panel module, and the motion of the manipulator is operated, so that the manipulator drives the stator part of the linear motor to move, and the stator part of the linear motor drives the laser and the laser needle to move, so as to change the position of the laser needle, wherein the manipulator can change the angle of the laser needle, and the injection angle of the laser needle is adjusted according to the different positions of the human tumor, so that the laser needle is accurately injected into the center position of the tumor.
As shown in fig. 1, fig. 2, fig. 3 and fig. 4, when the position between the laser needle and the malignant tumor needs to be adjusted, the linear motor is started by the control panel module, after the linear motor is started, the active cell part of the linear motor moves, and the medical imaging equipment (such as ultrasonic imaging) is intervened to detect the tumor and the position of the laser needle, and the switch of the control panel module is adjusted, so that the active cell part of the linear motor drives the laser needle connected to the laser to move, and the tip of the laser needle is accurately injected into the center position of the tumor.
As shown in fig. 1, 2, 3 and 4, the manipulator may be a multi-joint manipulator, so as to facilitate adjustment of the height and angle of the laser needle.
As shown in fig. 1, 2, 3 and 4, the base of the manipulator may further be provided with a plurality of rollers, so that the rollers drive the laser injector to move, so as to facilitate the transfer of the laser injector.
As shown in fig. 1, 2, 3 and 4, laser needles with different sizes are designed according to the positions of different tumors, for example, when the laser needles enter the digestive tract, uterus and other parts for treatment, the caliber of a needle tube of the laser needle is 0.5mm-1.5mm; the catheter entering the heart cavity has strict size requirements, so that the caliber of the needle tube of the laser needle entering the heart cavity is 0.5mm-1.0mm; the caliber of a needle tube of the laser needle entering the spleen is required to be 0.8mm; the laser needle conforming to the spleen is established, the laser needle is injected into the center part of the tumor in the spleen, and laser generated by the laser injector is coupled into the optical fiber of the laser needle, so that the laser is released at the tip of the laser needle, the released laser acts on the tumor, and cancer cells are killed by high temperature generated by the laser, so that the effect of treating the tumor is achieved.
As shown in fig. 1, 2, 3 and 4, the laser needle is made of monocrystalline silicon.
As shown in fig. 1, 2, 3 and 4, the laser adopts a laser with adjustable power, so as to adjust the energy of laser output by the laser and avoid damaging human tissues due to overlarge laser energy generated by the laser.
As shown in fig. 1, 2, 3 and 4, the laser may be a laser-50 carbon dioxide laser, etc., wherein the carbon dioxide laser generates infrared light, and the output wavelength is 10.6 microns, and the laser has good directivity. The monochromaticity is good, the energy conversion rate is high, the output power is high, the carbon dioxide laser generates carbon dioxide laser beam, the beam collimation is regulated by the beam expander, the carbon dioxide laser is focused by the focusing mirror and finally coupled into the optical fiber of the laser needle, and the laser needle releases tiny light spots to act on the center of the tumor, so that the power density of the light spots is highly concentrated, the temperature can reach 200-1000 ℃, the high temperature and certain pressure at the light spots have the capabilities of cutting, burning and oxidizing the tumor, and capillary vessels exposed at the laser needle can be sealed and condensed, so that human tissues outside the tumor do not bleed or bleed little.
As shown in FIG. 1, FIG. 2, FIG. 3 and FIG. 4, the type of the micro controller can be 511-STM32F723ZET6 micro controller, ATSAML21E17B-MUT micro controller or PIC32MZ2048ECH100-I/PF micro controller.
As shown in fig. 1, 2, 3 and 4, the specific steps of the present invention are used:
1. confirming the tumor position in the patient by adopting medical imaging equipment;
2. the manipulator is operated through the control panel module, so that the manipulator changes the positions of the linear motor and the laser needle, and the optimal angle of the laser needle injected into the tumor position of the human body is adjusted;
3. starting a linear motor through a control panel module, so that a rotor part of the linear motor is elongated, and a laser needle is driven to be injected into the center of a tumor;
4. starting a laser through a control panel module, adjusting the power of the laser, enabling the laser to generate required laser, adjusting the beam collimation through a beam expander, focusing through a focusing mirror, finally coupling into an optical fiber of a laser needle, releasing laser through the laser needle and acting on the central part of a malignant tumor, and killing variant cells by utilizing the high temperature generated by the laser;
5. the extension or contraction of the linear motor and the output power of the laser are regulated by the control panel module, so that the laser emitted by the laser needle head is completely acted on the tumor until cancer cells of the tumor are completely killed;
6. the laser is turned off through the control panel module, so that the laser stops working;
7. the linear motor rotor is regulated to shrink partially through the control panel module, so that the laser needle is driven to move out of the human body.
A manufacturing method of a laser syringe needle comprises an electroplating method for preparing the laser syringe needle;
the electroplating method comprises the following steps:
step 1: drawing monocrystalline silicon into an optical fiber shape required by a laser needle;
step 2: silver plating technology is adopted to integrally silver the surface of the optical fiber to form silver plated optical fiber;
step 3: plating a layer of thin copper on the surface of the silver-plated optical fiber by utilizing an electroplating technology, so as to form a copper-plated optical fiber;
the method comprises the following steps: plating a layer of thin nickel on the surface of the copper-plated optical fiber by utilizing an electroplating technology to form a nickel-plated optical fiber;
step 5: plating a layer of thin gold on the surface of the nickel-plated optical fiber by utilizing an electroplating technology to form a gold-plated optical fiber;
step 6: forming a needle tube of a laser needle at the front end of the gold-plated optical fiber by adopting a grinding and polishing technology;
step 7: manufacturing the tail part of the laser needle head at the tail part of the laser needle head by adopting a laser coupling technology;
step 8: grinding the front end of a needle tube of the preliminary laser needle into a tip meeting the requirements by adopting an optical fiber surface grinding and polishing technology;
step 9: adopting an optical fiber surface grinding and polishing technology to treat the tail end of the preliminary laser needle head into an end surface coupled with a laser;
step 10: the cross-sectional images of the front and rear ends of the laser needle are detected by a microscope to determine that the laser needle is made to meet the required requirements.
A manufacturing method of a laser syringe needle comprises an adhesion method for preparing the laser needle;
the bonding method comprises the following steps:
step 1: drawing a corresponding drawing according to the required laser needle, and manufacturing the needle tail and the needle tube of the corresponding laser needle according to the drawing;
step 2: drawing monocrystalline silicon into optical fibers required by a laser needle by using a Czochralski monocrystalline silicon technology according to a drawing;
step 3: the special AB glue for the optical fiber is used for bonding the optical fiber in the tail part of the laser needle head and the needle tube to form a preliminary laser needle head;
step 4: grinding and polishing the surface of the optical fiber, and polishing the front end of the preliminary needle tube into a tip meeting the requirements;
step 5: grinding and polishing the surface of an optical fiber, and processing the tail part of the needle head of the preliminary laser needle head into an end surface coupled with a laser;
step 6: and detecting the end face patterns of the tip and the tail of the laser needle by using a microscope to determine the compliance.
What has been described above is merely some embodiments of the present invention. It will be apparent to those skilled in the art that at least one of the modifications and improvements can be made without departing from the inventive concept.
Claims (2)
1. A manufacturing method of a laser syringe needle comprises a laser syringe and a laser needle connected to the output end of the laser syringe;
the laser injector comprises a linear motor and a laser, wherein the linear motor is used for driving the laser to move, and the laser is connected to a rotor straight shaft of the linear motor;
the laser needle comprises a needle tail, a needle tube, an optical fiber and AB glue, wherein the needle tail is connected to a laser of the laser injector, a cavity is formed in the needle tail, the needle tube is fixedly connected to the needle tail and is communicated with the cavity of the needle tail, the front end of the needle tube is the tip of a tangential plane, the optical fiber is positioned in the laser needle, one end of the optical fiber is positioned at the needle tail and is connected with the output end of the laser, the other end of the optical fiber is positioned at the tip of the needle tube, and the AB glue is filled in a gap between the cavity of the needle tail and the optical fiber;
the laser emits the required laser, the beam collimation is regulated by the beam expander, the laser is focused by the focusing lens and finally coupled into the optical fiber of the laser needle, the laser is released by the laser needle and acts on the central part of the malignant tumor, and the variant cells are killed by the high temperature generated by the laser;
the method is characterized in that: electroplating method for preparing laser needle;
the electroplating method comprises the following steps:
step 1: drawing monocrystalline silicon into an optical fiber shape required by a laser needle;
step 2: silver plating technology is adopted to integrally silver the surface of the optical fiber to form silver plated optical fiber;
step 3: plating a layer of thin copper on the surface of the silver-plated optical fiber by utilizing an electroplating technology, so as to form a copper-plated optical fiber;
the method comprises the following steps: plating a layer of thin nickel on the surface of the copper-plated optical fiber by utilizing an electroplating technology to form a nickel-plated optical fiber;
step 5: plating a layer of thin gold on the surface of the nickel-plated optical fiber by utilizing an electroplating technology to form a gold-plated optical fiber;
step 6: forming a needle tube of a laser needle at the front end of the gold-plated optical fiber by adopting a grinding and polishing technology;
step 7: manufacturing the tail part of the laser needle head at the tail part of the laser needle head by adopting a laser coupling technology;
step 8: grinding the front end of a needle tube of the preliminary laser needle into a tip meeting the requirements by adopting an optical fiber surface grinding and polishing technology;
step 9: adopting an optical fiber surface grinding and polishing technology to treat the tail end of the preliminary laser needle head into an end surface coupled with a laser;
step 10: the cross-sectional images of the front and rear ends of the laser needle are detected by a microscope to determine that the laser needle is made to meet the required requirements.
2. A method of manufacturing a laser syringe needle according to claim 1, comprising an adhesive method for preparing a laser needle;
the bonding method comprises the following steps:
step 1: drawing a corresponding drawing according to the required laser needle, and manufacturing the needle tail and the needle tube of the corresponding laser needle according to the drawing;
step 2: drawing monocrystalline silicon into optical fibers required by a laser needle by using a Czochralski monocrystalline silicon technology according to a drawing;
step 3: the special AB glue for the optical fiber is used for bonding the optical fiber in the tail part of the laser needle head and the needle tube to form a preliminary laser needle head;
step 4: grinding and polishing the surface of the optical fiber, and polishing the front end of the preliminary needle tube into a tip meeting the requirements;
step 5: grinding and polishing the surface of an optical fiber, and processing the tail part of the needle head of the preliminary laser needle head into an end surface coupled with a laser;
step 6: and detecting the end face patterns of the tip and the tail of the laser needle by using a microscope to determine the compliance.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202310228205.4A CN116549104A (en) | 2017-11-10 | 2017-11-10 | Laser injector device and manufacturing method of laser injector needle thereof |
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| CN202310228205.4A CN116549104A (en) | 2017-11-10 | 2017-11-10 | Laser injector device and manufacturing method of laser injector needle thereof |
| CN201711104573.9A CN107913464A (en) | 2017-11-10 | 2017-11-10 | A kind of production method of laser injection device and its laser syringe needle |
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| CN201711104573.9A Division CN107913464A (en) | 2017-11-10 | 2017-11-10 | A kind of production method of laser injection device and its laser syringe needle |
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| CN202310228205.4A Pending CN116549104A (en) | 2017-11-10 | 2017-11-10 | Laser injector device and manufacturing method of laser injector needle thereof |
| CN201711104573.9A Pending CN107913464A (en) | 2017-11-10 | 2017-11-10 | A kind of production method of laser injection device and its laser syringe needle |
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Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4564011A (en) * | 1982-03-22 | 1986-01-14 | Leon Goldman | Laser optic device and method |
| US5222953A (en) * | 1991-10-02 | 1993-06-29 | Kambiz Dowlatshahi | Apparatus for interstitial laser therapy having an improved temperature sensor for tissue being treated |
| US5468239A (en) * | 1992-04-13 | 1995-11-21 | Sorenson Laboratories, Inc. | Apparatus and methods for using a circumferential light-emitting surgical laser probe |
| JPH0759791A (en) * | 1993-08-23 | 1995-03-07 | Mochida Pharmaceut Co Ltd | Operation probe of carbon dioxide laser operation device |
| WO2001020999A1 (en) * | 1999-09-23 | 2001-03-29 | Trimedyne, Inc. | Materials and methods for inducing angiogenesis and the repair of mammalian tissue |
| JP2002200181A (en) * | 2000-10-31 | 2002-07-16 | Shigehiro Kubota | Laser treatment instrument |
| AU2002350313B2 (en) * | 2001-12-14 | 2005-12-01 | Monteris Medical Inc. | Hyperthermia treatment and probe therefor |
| AU2002367876A1 (en) * | 2002-04-19 | 2003-11-03 | Ray Freeman | Tissue penetration device |
| JP2008099923A (en) * | 2006-10-20 | 2008-05-01 | Kazunori Nosaka | Treatment device |
| WO2010014224A2 (en) * | 2008-07-28 | 2010-02-04 | Xintec Corporation | Multi-wavelength laser and method for contact ablation of tissue |
| CN101934106B (en) * | 2009-07-01 | 2012-06-20 | 重庆医科大学 | Laser driving needleless injection system |
| US20110015484A1 (en) * | 2009-07-16 | 2011-01-20 | Alvarez Jeffrey B | Endoscopic robotic catheter system |
| CN102499756B (en) * | 2011-11-09 | 2013-08-14 | 浙江大学 | Device for performing fetal reduction operation by utilizing lasers |
| CN103246019A (en) * | 2013-05-23 | 2013-08-14 | 深圳市天阳谷科技发展有限公司 | Fiber collimator |
| WO2016210135A1 (en) * | 2015-06-23 | 2016-12-29 | The Regents Of The University Of California | Precision injector/extractor for robot-assisted minimally-invasive surgery |
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2017
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