CN116549099B - Radio frequency ablation measurement and control system and measurement and control method - Google Patents
Radio frequency ablation measurement and control system and measurement and control method Download PDFInfo
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- 238000007674 radiofrequency ablation Methods 0.000 title claims abstract description 161
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
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- A—HUMAN NECESSITIES
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- A61B2018/00696—Controlled or regulated parameters
- A61B2018/00702—Power or energy
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- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1425—Needle
- A61B2018/143—Needle multiple needles
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- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
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Abstract
The invention relates to a radio frequency ablation measurement and control system and a measurement and control method, which relate to the technical field of radio frequency ablation and are used for accurately controlling the temperature of a radio frequency ablation needle and avoiding the phenomena of too low temperature and uneven thermal field at the edge position of an ablation area. According to the radio frequency ablation measurement and control system, after the main needle is designated as the temperature control element to adjust the working parameters of the main needle, the sub needle is designated as the temperature control element again to adjust the working parameters of the main needle, so that the problems that the temperature at the edge position is too low, the thermal field is uneven and the cell activity at the edge position cannot be completely killed can be avoided; or the radio frequency ablation instrument directly designates the stator needle as a temperature control element to adjust the working parameters of the stator needle, and can also solve the problems that the temperature at the edge position is too low and the thermal field is uneven so as not to completely kill the cell activity at the position.
Description
Technical Field
The invention relates to the technical field of radio frequency ablation, in particular to a radio frequency ablation measurement and control system and a measurement and control method.
Background
The current radio frequency ablation technology for tumor minimally invasive treatment has wide application, safety and reliability, the frequency range is generally between 200 and 500KHz, radio frequency energy is transmitted to the part of the operation electrode entering the tissue under the guidance of percutaneous puncture or a cavity mirror through a radio frequency cable connector and the operation electrode and forms a loop with a negative plate connected with the outside of the body, a high frequency electric field is formed, conductive particles and polarized molecules in the tissue around the operation electrode are excited to run at a high speed under the action of the high frequency electric field to form frictional heat, and when the temperature of the tissue reaches above 60 ℃, proteins in the tissue are coagulated, and irreversible necrosis is lost, so that the treatment effect is achieved.
The current in the ablation area is generally the most dense near the center point of the electrode, the area is the highest point of temperature, the temperature gradually decays when the center point of the electrode extends outwards from two sides (such as left and right sides or upper and lower sides) in the radial direction, if the temperature of the edge position is too low, cells at the position still have activity, ablation omission can be generated to cause postoperative recurrence, and if the temperature is further increased, the temperature of the center area is too high, so that the tissue at the position is encrusted and carbonized, and the like, which is unfavorable for smooth operation.
Disclosure of Invention
The invention provides a radio frequency ablation measurement and control system and a measurement and control method, which are used for accurately controlling the temperature of a radio frequency ablation needle and avoiding the phenomena of too low temperature and uneven temperature of a thermal field at the edge position of an ablation area.
According to a first aspect of the present invention there is provided a radio frequency ablation measurement and control system comprising a radio frequency ablator and a radio frequency ablator needle, the radio frequency ablator needle comprising a main needle and at least one sub-needle, the sub-needle being extendable or retractable from the periphery of the main needle;
the radio frequency ablation instrument is respectively connected with the main needle and the sub needle so as to receive signals fed back by the main needle and the sub needle;
the radio frequency ablation instrument is configured to designate the main needle as a temperature control element to adjust working parameters of the radio frequency ablation instrument, and then designate the sub needle as a temperature control element to adjust the working parameters of the radio frequency ablation instrument; or alternatively
The radio frequency ablation instrument is configured to designate only the sub-needle as a temperature control element to adjust an operating parameter of the radio frequency ablation instrument.
In one embodiment, the radio frequency ablation instrument is configured to designate the main needle as a temperature control element and to determine the temperature T of the main needle at the current time Main unit (t i ) Target temperature T with main needle s main part After the working parameters of the radio frequency ablation instrument are adjusted, designating the sub-needle as a temperature control element, and according to the temperature T of the sub-needle at the current moment Son (t i ) With target temperature T of sub-needle s-shaped son And adjusting the working parameters of the radio frequency ablation instrument again.
In one embodiment, the radio frequency ablation instrument is configured to designate only the sub-needle as a temperature control element and to determine the temperature T at the current time of the sub-needle Son (t i ) With the target temperature T of the sub-needle s-shaped son And adjusting the working parameters of the radio frequency ablation instrument.
In one embodiment, the operating parameters of the radiofrequency ablation instrument include the power P (t i ) When the radio frequency ablation instrument designates the main needle as a temperature control element, the power P (t i ) The temperature with the main needle satisfies the following relation:
P(t i )＝P(t i-1 )+ΔP；
ΔP＝K p [T e (t i )-T e (t i-1 )]+K j T e (t i )+K d [T e (t i )-2T e (t i-1 )+T e (t i-2 )]；
T e (t i )＝T main unit (t i )-T s main part ；
T e (t i-1 )＝T Main unit (t i-1 )-T s main part ；
T e (t i-2 )＝T Main unit (t i-2 )-T s main part ；
Wherein Δp is the power value to be adjusted;
t i i is a natural number greater than or equal to 2, which is the working time of the main needle at the current moment;
P(t i-1 ) The power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time is the power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time;
T e (t i-1 ) The temperature of the main needle at the i-1 th moment;
T e (t i-2 ) The temperature of the main needle at the i-2 th moment;
K p the numerical range of the temperature-regulated scaling factor is 0.4-1;
K j the numerical range of the integration time is 0.4-1;
K d the numerical range of the differential time is 0.5-1.
In one embodiment, the operating parameters of the radiofrequency ablation instrument include whenThe power P (t) output by the radio frequency ablation instrument to the radio frequency ablation needle at the previous moment i ) When the radio frequency ablation instrument designates the sub-needle as a temperature control element, the power P (t i ) The temperature with the sub-needle satisfies the following relation:
P(t i )＝P(t i-1 )+ΔP；
ΔP＝K p [T e (t i )-T e (t i-1 )]+K j T e (t i )+K d [T e (t i )-2T e (t i-1 )+T e (t i-2 )]；
T e (t i )＝T son (t i )-T s-shaped son ；
T e (t i-1 )＝T Son (t i-1 )-T s-shaped son ；
T e (t i-2 )＝T Son (t i-2 )-T s-shaped son ；
Wherein Δp is the power value to be adjusted;
t i i is a natural number greater than or equal to 2, which is the working time of the sub-needle at the current moment;
P(t i-1 ) The power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time is the power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time;
T e (t i-1 ) The temperature of the sub-needle at the i-1 th moment;
T e (t i-2 ) The temperature of the sub-needle at the i-2 th moment;
K p the numerical range of the temperature-regulated scaling factor is 0.4-1;
K j the numerical range of the integration time is 0.4-1;
K d the numerical range of the differential time is 0.5-1.
In one embodiment, the radiofrequency ablation instrument is configured to determine the current output voltage U (t i ),
The current output voltage U (t i ) And (3) withPower P (t) i ) The following relationship is satisfied:
wherein U is ref Is the reference voltage of the digital-to-analog converter;
P max is the maximum output power of the radio frequency ablation instrument.
In one embodiment, the radiofrequency ablation instrument is configured to determine the current output voltage U (t i ),
The current output voltage U (t i ) Power P (t) i ) The following relationship is satisfied:
wherein,for the power P (t) i ) The voltage of the corresponding radio frequency signal;
U ref is the reference voltage of the digital-to-analog converter;
P max is the maximum output power of the radio frequency ablation instrument.
According to a second aspect of the present invention, there is provided a radio frequency ablation measurement and control system comprising a radio frequency ablator and a radio frequency ablator needle, the radio frequency ablator needle comprising a main needle and at least one sub-needle, the sub-needle being extendable or retractable from the periphery of the main needle;
the radio frequency ablation instrument is respectively connected with the main needle and the sub needle so as to receive signals fed back by the main needle and the sub needle;
the radio frequency ablation instrument can designate the main needle and the main needle as temperature control elements, or designate only the sub needles as temperature control elements to adjust working parameters of the radio frequency ablation instrument;
when the radio frequency ablation instrument designates the sub-needle as a temperature control element, the radio frequency ablation instrument is configured to target temperature T according to the sub-needle s-shaped son Controlling the unfolding diameter D of the sub-needle, wherein the unfolding diameter D of the sub-needle and the target temperature T of the sub-needle s-shaped son The following relationship is satisfied:
wherein AD is the diameter of the ablation zone in the direction of the sub-needle deployment;
D t is a coefficient, and the numerical range is 10-30.
In one embodiment, the target temperature T of the primary needle s main part With the target temperature T of the sub-needle s-shaped son The following relationship is satisfied:
T s-shaped son ≤T s main part ≤T s-shaped son +20。
In one embodiment, the radio frequency ablation instrument is configured to designate the main needle as a temperature control element and to determine the temperature T of the main needle at the current time Main unit (t i ) Target temperature T with main needle s main part After the working parameters of the radio frequency ablation instrument are adjusted, designating the sub-needle as a temperature control element, and according to the temperature T of the sub-needle at the current moment Son (t i ) With target temperature T of sub-needle s-shaped son And adjusting the working parameters of the radio frequency ablation instrument again.
In one embodiment, when the radio frequency ablation instrument designates the sub-needle as a temperature control element, the sub-needle with the lowest temperature is set as the temperature control element preferentially, and the power P (t i ) The method comprises the steps of carrying out a first treatment on the surface of the Then, the radio frequency ablation instrument searches and judges the other sub-needle with the lowest current temperature again and sets the other sub-needle as a temperature control element so as to adjust the power P (t i ) Until the temperature of each sub-needle reaches the target temperature T s-shaped son 。
In one embodiment, the operating parameter package of the radio frequency ablatorThe power P (t) output by the radio frequency ablation instrument to the radio frequency ablation needle at the current moment i ) When the radio frequency ablation instrument designates the main needle as a temperature control element, the power P (t i ) The temperature with the main needle satisfies the following relation:
P(t i )＝P(t i-1 )+ΔP；
ΔP＝K p [T e (t i )-T e (t i-1 )]+K j T e (t i )+K d [T e (t i )-2T e (t i-1 )+T e (t i-2 )]；
T e (t i )＝T main unit (t i )-T s main part ；
T e (t i-1 )＝T Main unit (t i-1 )-T s main part ；
T e (t i-2 )＝T Main unit (t i-2 )-T s main part ；
Wherein Δp is the power value to be adjusted;
t i i is a natural number greater than or equal to 2, which is the working time of the main needle at the current moment;
P(t i-1 ) The power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time is the power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time;
T e (t i-1 ) The temperature of the main needle at the i-1 th moment;
T e (t i-2 ) The temperature of the main needle at the i-2 th moment;
K p the numerical range of the temperature-regulated scaling factor is 0.4-1;
K j the numerical range of the integration time is 0.4-1;
K d the numerical range of the differential time is 0.5-1.
In one embodiment, the operating parameters of the radiofrequency ablation instrument include the power P (t i ) When the radio frequency ablation instrument designates the sub-needle as a temperature control element,power P (t) i ) The temperature with the sub-needle satisfies the following relation:
P(t i )＝P(t i-1 )+ΔP；
ΔP＝K p [T e (t i )-T e (t i-1 )]+K j T e (t i )+K d [T e (t i )-2T e (t i-1 )+T e (t i-2 )]；
T e (t i )＝T son (t i )-T s-shaped son ；
T e (t i-1 )＝T Son (t i-1 )-T s-shaped son ；
T e (t i-2 )＝T Son (t i-2 )-T s-shaped son ；
Wherein Δp is the power value to be adjusted;
t i i is a natural number greater than or equal to 2, which is the working time of the sub-needle at the current moment;
P(t i-1 ) The power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time is the power output to the radio frequency ablation needle by the radio frequency ablation instrument at the i-1 time;
T e (t i-1 ) The temperature of the sub-needle at the i-1 th moment;
T e (t i-2 ) The temperature of the sub-needle at the i-2 th moment;
K p the numerical range of the temperature-regulated scaling factor is 0.4-1;
K j the numerical range of the integration time is 0.4-1;
K d the numerical range of the differential time is 0.5-1.
In one embodiment, the radiofrequency ablation instrument is configured to determine the current output voltage U (t i ),
The current output voltage U (t i ) Power P (t) i ) The following relationship is satisfied:
wherein U is ref Is the reference voltage of the digital-to-analog converter;
P max is the maximum output power of the radio frequency ablation instrument.
In one embodiment, the radiofrequency ablation instrument is configured to determine the current output voltage U (t i ),
The current output voltage U (t i ) Power P (t) i ) The following relationship is satisfied:
wherein,for the power P (t) i ) The voltage of the corresponding radio frequency signal;
U ref is the reference voltage of the digital-to-analog converter;
P max is the maximum output power of the radio frequency ablation instrument.
According to a third aspect of the present invention, the present invention provides a measurement and control method of a radio frequency ablation measurement and control system, comprising the following operation steps:
the method comprises the steps that after a main needle of a radio frequency ablation needle is designated as a temperature control element by the radio frequency ablation instrument to adjust working parameters of the radio frequency ablation instrument, a sub-needle of the radio frequency ablation needle is designated as a temperature control element to adjust the working parameters of the radio frequency ablation instrument; or alternatively
The radio frequency ablation instrument designates sub-needles of the radio frequency ablation needle as temperature control elements to adjust the working parameters of the radio frequency ablation instrument.
Compared with the prior art, the invention has the advantages that the radio frequency ablation instrument designates the main needle as the temperature control element to adjust the working parameters, and then designates the sub needle as the temperature control element to adjust the working parameters, thereby avoiding the problems that the temperature at the edge position is too low (for example, lower than 60 ℃) and the thermal field is uneven and the cell activity at the position can not be completely killed; or the radio frequency ablation instrument directly designates the stator needle as a temperature control element to adjust the working parameters of the stator needle, and can also solve the problems that the temperature at the edge position is too low (for example, lower than 60 ℃) and the thermal field is uneven so as not to completely kill the cell activity at the position.
Drawings
The invention will be described in more detail hereinafter on the basis of embodiments and with reference to the accompanying drawings.
FIG. 1 is a block diagram of the connection of the components of a radio frequency ablator in an embodiment of the invention;
FIG. 2 is a front view of a radio frequency ablation needle in an embodiment of the invention;
FIG. 3 is a schematic view of the temperature field of a radio frequency ablation needle in an embodiment of the invention;
fig. 4 is a schematic illustration of an ablation zone in an embodiment of the invention.
Reference numerals:
100. a radiofrequency ablation needle;
110. a main needle;
120. a sub-needle;
130. a handle; 140. a main needle temperature measuring element; 150. a sub-needle temperature measuring element; 160. an insulating layer; 170. a scale tube; 180. an ablation electrode; 190. a neutral electrode;
200. a radio frequency ablation instrument;
210. a main control unit; 220. a measurement and control unit; 230. a switching power supply (digital-to-analog converter); 240. a power source; 250. a filter; 260. a power switch;
Detailed Description
The invention will be further described with reference to the accompanying drawings.
As shown in fig. 1 and 2, the present invention provides a radio frequency ablation measurement and control system, which comprises a radio frequency ablation instrument 200 and a radio frequency ablation needle 100. As shown in fig. 2, the rf ablation needle 100 includes a main needle 110 and at least one sub-needle 120, and the rf ablation instrument 200 is connected to the main needle 110 and the sub-needle 120, respectively, to receive signals fed back from the main needle 110 and the sub-needle 120. For example, when the main needle 110 and the sub-needle 120 feed back temperature signals, the rf ablation apparatus 200 may determine whether the current temperature of the main needle 110 and/or the sub-needle 120 reaches the target temperature according to the temperature signals fed back by the main needle 110 and/or the sub-needle 120, and if not, adjust the working parameters of the rf ablation apparatus 200 accordingly, for example, increase or decrease the power thereof according to the difference between the current temperature of the main needle 110 and/or the sub-needle 120 and the target temperature, so that the temperature of the main needle 110 and/or the sub-needle 120 changes accordingly to reach the target temperature.
Example 1
In this embodiment 1, the rf ablation apparatus 200 is configured to designate the main needle 110 as a temperature control element to adjust the operation parameters of the rf ablation apparatus 200, and designate the sub-needle 120 as a temperature control element to adjust the operation parameters of the rf ablation apparatus 200.
Specifically, the RF ablation instrument 200 is configured to first designate the main needle 110 as a temperature control element, and to determine the temperature T of the main needle 110 at the current time Main unit (t i ) Target temperature T with main needle 110 s main part After the working parameters of the radio frequency ablation instrument 200 are adjusted, the sub-needle 120 is designated as a temperature control element, and the temperature T at the current moment of the sub-needle 120 is determined Son (t i ) With target temperature T of sub-needle s-shaped son The operating parameters of the radiofrequency ablation instrument 200 are again adjusted.
When the rf ablation apparatus 200 designates the main needle 110 as the temperature control element, the rf ablation apparatus 200 only determines the temperature T of the main needle 110 at the current time, although the rf ablation apparatus 200 receives the temperature signals fed back by the main needle 110 and the sub-needles 120 Main unit (t i ) Whether or not to reach its target temperature T s main part Without judging the relationship between the temperature of the sub-needle 120 and its target temperature; conversely, when the rf ablation apparatus 200 designates the sub-needle 120 as the temperature control element, the rf ablation apparatus 200 only determines the temperature T of the sub-needle 120 at the current time, although the rf ablation apparatus 200 still receives the temperature signals fed back by the main needle 110 and the sub-needle 120 Son (t i ) Whether or not to reach its target temperature T s-shaped son And no longer focuses on the relationship between the temperature of the primary needle 110 and its target temperature.
That is, in the present embodiment 1, the radio frequency ablation instrument 200 operates by replacing the temperature control element. The reason why the rf ablation instrument 200 replaces the temperature controlling element is that, during treatment, an ablation area (for example, a circle with a radius of about 4cm as shown in fig. 3) formed by the main needle 110 presents an energy field gradually decaying outwards from a position where the main needle 110 is located, because an electrode for receiving rf energy of the rf ablation instrument 200 is located on the main needle 110, and the position where the main needle 110 is located is a central position of the ablation area, so that the closer to the electrode (for example, the central position) the energy is the most dense, and accordingly, the area is the position with the highest temperature; each 1cm of the radial extension from both sides (e.g., left and right sides or upper and lower sides) in the radial direction of the center position attenuates the temperature by about 10 c (as shown in fig. 3, the temperature is highest at the center point of a circle having a radius of about 4cm, about 95 c, and the temperature is lowest at the most edge region, about 55 c). That is, the energy and temperature are maximized at the center position where the main needle 110 is located; the smaller the energy and temperature, the farther the main needle 110 is from, which causes the temperature at the location (center location) of the main needle 110 to be too high (e.g., above 90 ℃) and the temperature at the edge location of the ablation zone to have not reached the target temperature. If the temperature at the edge is too low (e.g., below 60 ℃), cells may still be active, and ablation may be omitted, which may result in incomplete surgery, so that the energy input to the main needle 110 is generally increased, which in turn may cause the temperature at the location (central location) of the main needle 110 to be too high, and may generate crusting and charring, which may be detrimental to normal operation.
Based on the above-mentioned problems, the present invention enables the temperature T of the main needle 110 at the current moment by replacing the temperature control element Main unit (t i ) Has reached its target temperature T s main part At this time, the sub-needle 120 is set as a temperature control element, thereby controlling the temperature of the sub-needle 120. Since the sub-needle 120 is located in the circumferential direction of the main needle 110, the sub-needle 120 is located at an edge position far from the center with respect to the ablation region formed by the main needle 110, and thus the temperature of the sub-needle 120 can be adjusted to reach the target temperature by controlling the energy input to the sub-needle 120, thereby ensuring the temperature at the edge positionThe temperature can reach the target temperature, so that the temperature at the edge position reaches the temperature capable of completely killing the activity of cells at the edge position, and the phenomenon of incomplete operation caused by ablation omission is avoided. On the other hand, since the energy field is superimposed on the energy field of the center position of the main needle 110 when the energy is inputted to the sub-needle 120, the temperature of the main needle 110 is further increased by the T of the main needle 110 s main part Set to less than its limit temperature (e.g., less than 90 ℃), and/or by setting the T of the sub-needle 110 s-shaped son Is set to be less than its limit temperature (e.g., less than 85 deg.c) to avoid the problem of excessive temperature at the location (center location) of the main needle 110.
The operating parameters of the rf ablation instrument 200 include the power P (t) output by the rf ablation instrument 200 to the rf ablation needle 100 at the current time i ) The power P (t i ) The temperature of the main needle 110 and the sub-needle 120 of the rf ablation instrument 200 may be affected. In general, the power P (t i ) The larger the temperature of the main needle 110 and the sub-needle 120 is, the larger the power P (t i ) The smaller the temperature of the main needle 110 and the sub-needle 120 is, the smaller the power P (t i ) When reduced to 0, the temperatures of the main needle 110 and the sub needle 120 may temporarily maintain the current temperature.
When the rf ablation apparatus 200 designates the main needle 110 as a temperature control element, the power P (t i ) The temperature with the main needle 110 satisfies the following relation (1):
P(t i )＝P(t i-1 )+ΔP；
ΔP ＝K p [T e (t i )-T e (t i-1 )]+ K j T e (t i )+ K d [T e (t i )-2T e (t i-1 )+ T e (t i-2 )]； (1-1)
T e (t i )＝ T main unit (t i )-T s main part ； (1-3)
T e (t i-1 )＝ T Main unit (t i-1 )-T s main part ； (1-4)
T e (t i-2 )＝ T Main unit (t i-2 )-T s main part ； (1-5)
Wherein ΔP is the power value to be adjusted, t i I is a natural number greater than or equal to 2, which is the working time of the main needle 110 at the current moment; p (t) i-1 ) The power output by the radio frequency ablation instrument 200 to the radio frequency ablation needle 100 at the i-1 time; t (T) e (t i-1 ) The temperature of the main needle 110 at time i-1; t (T) e (t i-2 ) The temperature of the main needle 110 at time i-2; k (K) p The numerical range of the temperature-regulated scaling factor is 0.4-1; k (K) j The numerical range of the integration time is 0.4-1; k (K) d The numerical range of the differential time is 0.5-1.
That is, the RF ablation device 200 is based on the temperature of the main needle 110 at the current time (i.e. the ith time) and the target temperature T thereof s main part The relation between the temperature at the time immediately before the i-th time (i.e. the i-1-th time) and the target temperature T thereof s main part The relation between the temperature at the time immediately preceding the i-1 st time (i.e., the i-2 nd time) and the target temperature T thereof s main part To determine the power P (t i ). That is, the radio frequency ablation instrument 200 compares the temperature monitoring value (the temperature at the current time) with the set target temperature by an incremental PID control algorithm, and adjusts the power P (t) based on the comparison result i ) (e.g., for power P (t) i ) Increasing or decreasing) to enable the temperature to reach the target temperature. By the control method, the controlled temperature can gradually reach the preset target temperature, and the problem of excessive oscillation of temperature control is avoided.
Accordingly, the power P (t i ) In relation to the temperature value of the previous two times, the power at the current moment P (t i ) And carrying out iterative calculation according to the temperature values of the last two times so as to avoid introducing more irrelevant temperature data and reduce certain calculated amount.
Further, as described above, when the temperature of the main needle 110 reaches the target temperature value, the rf ablator 200 stops or decreases the power output; to avoid that the temperature at the edge location of the ablation zone has not reached the target temperature, the radiofrequency ablation instrument 200 will designate the sub-needle 120 as a temperature control element.
When the radio frequency ablation instrument 200 designates the stator needle 120 as a temperature control element, the power P (t i ) With the current temperature T of the sub-needle 120 Son (t i ) Target temperature T with sub-needle 120 s-shaped son The following relationship is satisfied:
P(t i )＝P(t i-1 )+ΔP；
ΔP ＝K p [T e (t i )-T e (t i-1 )]+ K j T e (t i )+ K d [T e (t i )-2T e (t i-1 )+ T e (t i-2 )]； (1-2)
T e (t i )＝T son (t i )-T s-shaped son ；
T e (t i-1 )＝T Son (t i-1 )-T s-shaped son ；
T e (t i-2 )＝T Son (t i-2 )-T s-shaped son ；
Wherein ΔP is the power value to be adjusted, t i I is a natural number greater than or equal to 2, which is the working time of the sub-needle 120 at the current moment; p (t) i-1 ) The power output by the radio frequency ablation instrument 200 to the radio frequency ablation needle 100 at the i-1 time; t (T) e (t i-1 ) The temperature of the sub-needle 120 at time i-1; t (T) e (t i-2 ) The temperature of the sub-needle 120 at time i-2; k (K) p The numerical range of the temperature-regulated scaling factor is 0.4-1; k (K) j The numerical range of the integration time is 0.4-1; k (K) d The numerical range of the differential time is 0.5-1.
That is, the rf ablator 200 may adjust its power output to the sub-needle 120 as per the control method described above for adjusting the main needle 110. When the temperature of the sub-needle 120 reaches its target temperature, a temperature control timer is started to reach the desired ablation range.
When the radio frequency ablation instrument 200 uses the designated sub-needles 120 as the temperature control elements, some sub-needles 120 (1 or more) with the lowest temperature are preferentially arranged as the temperature control elements, namelyAdjusting the power P (t) at the current time according to the temperature of the lowest temperature sub-needle 120 i ) To expect that the temperature of the sub-needle 120 can reach the target temperature T thereof s-shaped son The method comprises the steps of carrying out a first treatment on the surface of the Subsequently, another sub-needle 120 (may be 1 or more) having the lowest current temperature is found and judged again, and is set as a temperature control element to adjust the power P (t) i ) Repeating the above steps to make the temperature of each sub-needle 120 reach the target temperature T s-shaped son 。
After obtaining the power output to the rf ablation needle 100 according to the temperatures of the main needle 110 and the sub-needle 120, the current output voltage U (t i ) In such a manner that the power output by the power source reaches the power P (t i )。
Specifically, the current output voltage U (t i ) Power P (t) i ) The following relationship is satisfied:
wherein U is ref The reference voltage of the digital-to-analog converter is generally 1-5V; p (P) max The maximum output power of the rf ablator 200 is typically 150-500W.
The above-mentioned relational expression (1-3) can also be written in the form of the following relational expression (1-4):
in the above-mentioned relational expression (1-4),
wherein D is factor For the coefficients of the power and the digital-to-analog conversion value, AD is the full amplitude of the digital-to-analog converter, which is related to the bit number (generally 10-24 bits) of the digital-to-analog converter, and the AD takes on the value 1024-16777216. Thus, the current output voltage U (t i ) Finally, the power required to be set at this time, namely the power P (t) i )。
In addition, the voltage U of the radio frequency signal corresponding to the power to be set at this time can be adjusted according to the real-time tissue impedance R detected by the radio frequency ablation instrument 200 p (t i )。
Specifically, the current output voltage U (t i ) Power P (t) i ) The following relationship is satisfied:
wherein,for the power P (t) i ) The voltage of the corresponding radio frequency signal; u (U) ref The reference voltage of the digital-to-analog converter is generally 1-5V; p (P) max The maximum output power of the rf ablator 200 is typically 150-500W.
Thus, the above-mentioned relational expression (1-5) can be written in the form of the following relational expression (1-6):
wherein D is factor For the coefficients of the power and the digital-to-analog conversion value, AD is the full amplitude of the digital-to-analog converter, which is related to the bit number (generally 10-24 bits) of the digital-to-analog converter, and the AD takes on the value 1024-16777216. Thus, the current output voltage U (t i ) Finally, the power required to be set at this time, namely the power P (t) i )。
When the temperature of the sub-needle 120 reaches the target temperature, the rf ablator 200 maintains the output current power P (t i ) For a certain time (for example, 5-20 min) to achieve the thermal deposition effect and consolidate the therapeutic effect.
The radio frequency ablator 200 designates the sub-needle 120 as a temperature control elementIn this case, the RF ablation instrument 200 is further configured to target the temperature T based on the sub-needle 120 s-shaped son Controlling the unfolding diameter D of the sub-needle 120, wherein the unfolding diameter D of the sub-needle 120 and the target temperature T of the sub-needle 120 s-shaped son The following relationship is satisfied:
where AD is the diameter of the ablation zone in the direction of deployment of the sub-needle 120; d (D) t Is a coefficient, and the numerical range is 10-30.
As shown in fig. 4, the shape of the ablation region formed in the expanding direction of the sub-needle 120 is a circle of diameter AD (the thermal field distribution takes the shape of an oblate spheroid in three dimensions). The upper ablation height of the plane of the sub-needle 120 is AH1, and the lower ablation height of the plane of the sub-needle 120 is AH2. Wherein the upper ablation height AH1 is an amount that varies with power P and time t, which may range from 0-20mm; the lower ablation height AH2 is an amount that varies with power P and time t and may range from 0-10mm.
Target temperature T of main needle 110 s main part Target temperature T with sub-needle 120 s-shaped son The following relationship is satisfied:
T s-shaped son ≤T s main part ≤T s-shaped son +20。
Target temperature T of sub-needle 120 s-shaped son Can be 54-100 ℃, D t Is a factor (ablation diameter and temperature control time factor), wherein the temperature control time is typically 5-10min, i.e. the radio frequency ablator 200 described above keeps outputting the current power P (t i ) For a certain time.
In other embodiments, the deployed diameter D of the sub-needle 120 of the rf ablation needle 100 may be determined according to the size of the designated area to be ablated. As shown in fig. 4, the diameter of the deployed sub-needle is D, and the ablation range can be set according to the power P (t i ) And the time t.
The overall morphology distribution of the thermal field is as follows: the ablation form of the sub-needle 120 in the deployment direction is a circle with a diameter AD, the ablation height of the upper part of the plane of the sub-needle 120 is AH1, and the ablation height of the lower part of the plane of the sub-needle 120 is AH2.
At different settings of power P and time t, ablation diameter AD satisfies the following definition:
AD＝D+2×SW；
where SW is the coefficient of the ablation range of the outward extension of the sub-needle 120, which is a function of power P (t i ) And the variation of time t, the value range is 0-10mm.
The power P is generally set to 50-200W and the time t is 5-20min. An oblate spheroid is formed after ablation. Total (S)
The ablation height at the upper part of the plane where the sub-needle 120 is located is AH1, which is power P (t i ) And the amount of time t change, the value range is 0-20mm.
The ablation height at the upper part of the plane where the sub-needle 120 is located is AH2, which is power P (t i ) And the amount of time t change, the value range is 0-20mm.
Example 2
Unlike embodiment 1 described above, the rf ablation instrument 200 is configured to designate only the sub-needle 120 as a temperature control element to adjust the operating parameters of the rf ablation instrument 200. In other words, the radiofrequency ablation instrument 200 may not pay attention to the relationship between the temperature of the main needle 110 and its target temperature, but only determine the relationship between the temperature of the sub-needle 120 and its target temperature. Because the temperature of the central location of the ablation zone is highest based on the analysis described above, the temperature of the main needle 110 at the central location will generally also achieve the desired target as long as the temperature of the sub-needle 120 can achieve the desired target.
Specifically, the radiofrequency ablation instrument 200 is configured to designate only the sub-needle 120 as a temperature control element, and to determine the temperature T at the current time of the sub-needle 120 Son (t i ) Target temperature T with sub-needle 120 s-shaped son The operating parameters of the radiofrequency ablation instrument 200 are adjusted.
The operating parameters of the rf ablation instrument 200 include the power P (t) output by the rf ablation instrument 200 to the rf ablation needle 100 at the current time i ) When the radiofrequency ablation instrument 200 designates the stator needle 120 as a temperature control element, the power P (t i ) With the current temperature T of the sub-needle 120 Son (t i ) Target temperature T with sub-needle 120 s-shaped son The following relationship is satisfied:
P(t i )＝P(t i-1 )+ΔP；
ΔP＝K p [T e (t i )-T e (t i-1 )]+ K j T e (t i )+ K d [T e (t i )-2T e (t i-1 )+ T e (t i-2 )]； (2-1)
T e (t i )＝T son (t i )-T s-shaped son ；
T e (t i-1 )＝T Son (t i-1 )-T s-shaped son ；
T e (t i-2 )＝T Son (t i-2 )-T s-shaped son ；
Wherein t is i I is a natural number greater than or equal to 2, which is the working time of the sub-needle 120 at the current moment; p (t) i-1 ) The power output by the radio frequency ablation instrument 200 to the radio frequency ablation needle 100 at the i-1 time; t (T) e (t i-1 ) The temperature of the sub-needle 120 at time i-1; t (T) e (t i-2 ) The temperature of the sub-needle 120 at time i-2; k (K) p The numerical range of the temperature-regulated scaling factor is 0.4-1; k (K) j The numerical range of the integration time is 0.4-1; k (K) d The numerical range of the differential time is 0.5-1.
That is, the RF ablation device 200 is based on the temperature of the sub-needle 120 at the current time (i.e. the i-th time) and the target temperature T thereof s-shaped son The relation between the temperature at the time immediately before the i-th time (i.e. the i-1-th time) and the target temperature T thereof s-shaped son The relation between the temperature at the time immediately preceding the i-1 st time (i.e., the i-2 nd time) and the target temperature T thereof s-shaped son To determine the power P (t i ). That is, the radio frequency ablation instrument 200 compares the temperature monitoring value (the temperature at the current time) with the set target temperature by an incremental PID control algorithm, and adjusts the power P (t) based on the comparison result i ) (e.g., for power P (t) i ) Increasing or decreasing) to enable the temperature to reach the targetAnd (5) marking the temperature. By the control method, the controlled temperature can gradually reach the preset target temperature, and the problem of excessive oscillation of temperature control is avoided.
Further, in the present embodiment 2, the current output voltage U (t i ) Power P (t) i ) The relation (1-3) or the relation (1-5) to obtain the power required to be set at this time, namely the power P (t) at the current moment i ) The present invention will not be described in detail.
It will be appreciated that in this embodiment 2, the relationship of (1-6) in the above embodiment 1 can be used to obtain the deployment diameter of the sub-needle 120, which is not described in detail in the present invention.
On the basis of the above embodiments 1 and 2, as shown in fig. 1, the radio frequency ablation apparatus 200 includes a main control unit 210, a measurement and control unit 220, a switching power supply (digital-to-analog converter) 230, a power source 240, a filter 250, and a power switch 260, and the arrows in fig. 1 indicate the flow direction of signals.
The main control unit 210 may generate rf energy based on the set parameters or the measurement and control unit 220 calculates the tuned parameters according to the temperature fed back. The measurement and control unit 220 is used for detecting the state of the rf ablation electrode and the power source switch, and obtaining the temperature measurement value fed back by the sub-needle 120 or the main needle 110, and the main control unit 210 controls the output of the power source 240 according to the analog voltage generated by the corresponding set temperature value. The switching power supply (digital-to-analog converter) 230 is used to change the input ac power supply into dc power supply. The power source 240 is configured to generate the radio frequency energy, such as 470KHz radio frequency energy.
Wherein, the measurement and control unit 220 is in communication connection with the radio frequency ablation needle 100. More specifically, the measurement and control unit 220 is connected to the ablation electrode 180 (which may be used as an anode and extend into the target position in the body along with the main needle 110) and the neutral electrode 190 (which may be used as a cathode and form a current loop with the ablation electrode 180 on the main needle 110, which may be attached to the epidermis of the human body), and the ablation electrode 180 (which may be used as an anode and extend into the target position in the body along with the sub needle 120) and the neutral electrode 190 (which may be used as an cathode and form a current loop with the ablation electrode 180 on the sub needle 120, which may be attached to the epidermis of the human body) on the main needle 110, respectively, so as to control the on-off state thereof. In addition, the measurement and control unit 220 is further connected to the temperature measuring element on the main needle 110 and the temperature measuring element on the sub-needle 120, respectively, so as to obtain temperature data of the main needle 110 and the sub-needle 120, respectively. Wherein the temperature sensing element on the main needle 110 may be disposed in the ablation electrode 180 on the main needle 110 and the temperature sensing element on the sub-needle 120 may be disposed in the ablation electrode 180 on the sub-needle 120.
The measurement and control unit 220 is in communication connection with the main control unit 210, so that the acquired temperature signal is fed back to the main control unit 210, and the main control unit 210 determines the power required to be set according to judgment and calculation and transmits the power signal to the measurement and control unit 220.
The main control unit 210 is further connected to a switching power supply (digital-to-analog converter) 230 and a power source 240, where the switching power supply (digital-to-analog converter) 230 is connected to the power source 240, and the main control unit 210 can obtain the current output voltage by modulating the switching power supply (digital-to-analog converter) 230, and finally obtain the power to be set.
In addition, the power switch 260 is connected to a filter 250, and the filter 250 is used for filtering the mains voltage fluctuation of the input ac power. The filter 250 can filter out the fluctuation of the grid voltage of the purified input alternating current power supply, so that the grid voltage is stable and reliable. The filter 250 is connected to a switching power supply (digital-to-analog converter) 230.
The measurement and control unit 220 has a plurality of switching devices and N relays to control the rf energy and electrode output switching. The main control unit 210 generates a corresponding analog voltage value according to the temperature value fed back by the main control unit and a preset target temperature value, so as to control the power output by the power source 240. That is, the main control unit 210 can control the output of the power source 240 according to the temperature value obtained by the measurement and control unit 220, and monitor the temperature value of the central position of the ablation region where the main needle 110 of the rf ablation needle 100 is located and the edge position of the ablation region where the sub-needle 120 is located in real time, so as to determine the duration of the ablation region.
The measurement and control unit 220 monitors the reflux impedance of the neutral electrode 190 when the rf ablation needle 100 works to determine whether the neutral electrode is disconnected or connected, so as to avoid skin injury and ensure the safety of the operation.
Based on the above embodiments 1 and 2, as shown in fig. 2, the rf ablation needle 100 further includes a handle 130. Wherein the main needle 110 and the sub-needle 120 are connected to the handle 130, and the sub-needle 120 can be extended or retracted from the outer circumference of the main needle 110. When the sub-needle 120 is deployed, it is extended and deployed from the gap between the tip of the main needle 110 and the needle tube, and conversely, the sub-needle 120 is retracted from the gap. The rf ablation needle 100 may take the form of a conventional structure including a main needle and a sub-needle, such as the rf ablation electrode needle disclosed in chinese patent CN115444551a, which is incorporated herein by reference in its entirety.
Temperature measuring elements (e.g., thermocouples, etc.) may be disposed on the main needle 110 and the sub-needle 120 to measure the temperature of the main needle 110 and the sub-needle 120 and feed back temperature signals to the measurement and control unit 220 of the rf ablation apparatus 200. As shown in FIG. 2, the main needle temperature measuring element 140 on the main needle 110 may be disposed at the root position of the main needle 110, and the sub-needle temperature measuring element 150 on the sub-needle 120 may be disposed at the tip position of the sub-needle 120.
The number of the sub-needles 120 may be 1 or more, and the plurality of sub-needles 120 may be wound around the circumference of the main needle 110, so that the sub-needles 120 may be umbrella-shaped or otherwise shaped when being unfolded. When there are a plurality of sub-needles 120, a temperature measuring element may be provided on each sub-needle 120, or a temperature measuring element may be provided on only a part of the sub-needles 120 (for example, as shown in fig. 2, a sub-needle 120 provided with a temperature measuring element and a sub-needle 120 not provided with a temperature measuring element are provided at a distance).
It should be noted that, since the sub-needle 120 provided with the temperature measuring element can feed back the temperature signal to the radio frequency ablation instrument 200, the temperature measuring element can be designated as a temperature controlling element by the radio frequency ablation instrument 200; the sub-pins 120 without the temperature measuring element cannot be set as the temperature controlling element.
In addition, the main needle 110 may be coated with an insulation layer 160 on the needle tube portion thereof to insulate the needle tube portion thereof. The needle cannula is configured in the form of a graduated tube 170 so that the depth of insertion of the primary needle 110 into the target site may be indicated.
The tip of the main needle 110 may take the form of a three-edged tip, which has electrical conductivity. The tip of the main needle 110 is connected to a central tube in the graduated tube 170. When the scale tube 170 is moved, a gap is formed between the scale tube and the central tube, and the sub-needle 120 can be extended and unfolded from the gap.
The terminal conductive part of the scale tube 170 is connected with a high-frequency wire, the high-frequency wire is connected with a PCB adapter plate, and the PCB adapter plate is connected with the measurement and control unit 220 of the radio frequency ablation instrument 200 through a radio frequency connector. The main needle temperature measuring element 140 is arranged at the top end of the needle tip inner cavity of the main needle 110 communicated with the inner cavity of the central tube, and the tail end of the main needle temperature measuring element 140 is respectively connected with the PCB adapter plate and the radio frequency connector, so that the main needle temperature measuring element 140 can be communicated with the measurement and control unit 220 of the radio frequency ablation instrument 200. The sub-needle temperature measuring element 150 is disposed at the top end of the inner cavity of the sub-needle 120, and the tail ends thereof are respectively connected with the PCB adapter plate and the radio frequency connector, thereby being capable of communicating with the measurement and control unit 220 of the radio frequency ablation instrument 200.
The tip of the main needle 110 may be made of an anti-sticking material so that it is not adhered to tissues to ensure stable conductivity and prevent scabbing due to an excessive center temperature.
Example 3
On the basis of the embodiment 1 and the embodiment 2, the invention also provides a measurement and control method of the radio frequency ablation measurement and control system, which comprises the following operation steps:
after the main needle 110 of the rf ablation needle 100 is designated as a temperature control element by the rf ablation instrument 200 to adjust the working parameters of the rf ablation instrument 200, the sub-needles 120 of the rf ablation needle 100 are designated as temperature control elements to adjust the working parameters of the rf ablation instrument 200.
Alternatively, the radiofrequency ablation instrument 200 designates the sub-needles 120 of the radiofrequency ablation needle 100 as temperature control elements to adjust the operating parameters of the radiofrequency ablation instrument 200.
The specific adjustment process of the working parameters of the rf ablation apparatus 200 is shown in the above-mentioned embodiments 1 and 2, and the description thereof is omitted herein.
The measurement and control method is applied to the experiment or test stage of the radio frequency ablation measurement and control system.
While the invention has been described with reference to a preferred embodiment, various modifications may be made and equivalents may be substituted for elements thereof without departing from the scope of the invention. In particular, the technical features mentioned in the respective embodiments may be combined in any manner as long as there is no structural conflict. The present invention is not limited to the specific embodiments disclosed herein, but encompasses all technical solutions falling within the scope of the claims.
Claims (5)
1. A radio frequency ablation measurement and control system, characterized by comprising a radio frequency ablation instrument (200) and a radio frequency ablation needle (100), the radio frequency ablation needle (100) comprising a main needle (110) and at least one sub-needle (120), the sub-needle (120) being extendable or retractable from the periphery of the main needle (110);
the radio frequency ablation instrument (200) is respectively connected with the main needle (110) and the sub-needle (120) to receive signals fed back by the main needle (110) and the sub-needle (120);
wherein, the radio frequency ablation instrument (200) is configured to designate the main needle (110) as a temperature control element to adjust the working parameters of the radio frequency ablation instrument (200), and then designate the sub-needle (120) as a temperature control element to adjust the working parameters of the radio frequency ablation instrument (200); the radio frequency ablation instrument (200) is configured to designate the main needle (110) as a temperature control element and to determine the temperature T of the main needle (110) at the current moment Main unit (t i ) Target temperature T with the main needle (110) s main part After the working parameters of the radio frequency ablation instrument (200) are adjusted, designating the sub-needle (120) as a temperature control element, and according to the temperature T of the sub-needle (120) at the current moment Son (t i ) With target temperature T of sub-needle s-shaped son Readjusting the operating parameters of the radiofrequency ablation instrument (200);
the working parameters of the radio frequency ablation instrument (200) comprise the power P (t) output by the radio frequency ablation instrument (200) to the radio frequency ablation needle (100) at the current moment i ) When the radio frequency ablation instrument (200) designates the main needle (110) as a temperature control element, the power P (t) at the current moment i ) The temperature of the main needle (110) satisfies the following relation:
P(t i )＝P(t i-1 )+ΔP；
ΔP＝K p [T e (t i )-T e (t i-1 )]+K j T e (t i )+K d [T e (t i )-2T e (t i-1 )+T e (t i-2 )]；
T e (t i )＝T main unit (t i )-T s main part ；
T e (t i-1 )＝T Main unit (t i-1 )-T s main part ；
T e (t i-2 )＝T Main unit (t i-2 )-T s main part ；
Wherein Δp is the power value to be adjusted;
t i i is a natural number greater than or equal to 2, which is the working time of the main needle (110) at the current moment;
P(t i-1 ) Outputting power to the radio frequency ablation needle (100) for the radio frequency ablation instrument (200) at the i-1 th moment;
T e (t i-1 ) Is the temperature of the main needle (110) at time i-1;
T e (t i-2 ) Is the temperature of the main needle (110) at time i-2;
K p the numerical range of the temperature-regulated scaling factor is 0.4-1;
K j the numerical range of the integration time is 0.4-1;
K d the numerical range of the differential time is 0.5-1.
2. The radiofrequency ablation measurement and control system according to claim 1, characterized in that the operating parameters of the radiofrequency ablation instrument (200) comprise the power P (t i ) When the radio frequency ablation instrument (200) designates the sub-needle (120) as a temperature control element, the power P (t) at the current moment i ) The temperature of the sub-needle (120) satisfies the following relation:
P(t i )＝P(t i-1 )+ΔP；
ΔP＝K p [T e (t i )-T e (t i-1 )]+K j T e (t i )+K d [T e (t i )-2T e (t i-1 )+T e (t i-2 )]；
T e (t i )＝T son (t i )-T s-shaped son ；
T e (t i-1 )＝T Son (t i-1 )-T s-shaped son ；
T e (t i-2 )＝T Son (t i-2 )-T s-shaped son ；
Wherein Δp is the power value to be adjusted;
t i i is a natural number greater than or equal to 2, which is the working time of the sub-needle (120) at the current moment;
P(t i-1 ) Outputting power to the radio frequency ablation needle (100) for the radio frequency ablation instrument (200) at the i-1 th moment;
T e (t i-1 ) The temperature of the sub-needle (120) at the i-1 th moment;
T e (t i-2 ) The temperature of the sub-needle (120) at time i-2;
K p the numerical range of the temperature-regulated scaling factor is 0.4-1;
K j the numerical range of the integration time is 0.4-1;
K d the numerical range of the differential time is 0.5-1.
3. The radiofrequency ablation measurement and control system according to claim 1, characterized in that the radiofrequency ablation instrument (200) is configured to control the current output voltage U (t) of the radiofrequency ablation instrument (200) by adjusting the current output voltage U (t i ),
The current output voltage U (t) of the radio frequency ablation instrument (200) i ) Power P (t) i ) The following relationship is satisfied:
wherein U is ref Is the reference voltage of the digital-to-analog converter;
P max is the maximum of the radio frequency ablation instrument (200)Is set, and the output power of the same is set.
4. The radiofrequency ablation measurement and control system according to claim 1, characterized in that the radiofrequency ablation instrument (200) is configured to control the current output voltage U (t) of the radiofrequency ablation instrument (200) by adjusting the current output voltage U (t i ),
The current output voltage U (t) of the radio frequency ablation instrument (200) i ) Power P (t) i ) The following relationship is satisfied:
wherein,for the power P (t) i ) The voltage of the corresponding radio frequency signal;
U ref is the reference voltage of the digital-to-analog converter;
P max is the maximum output power of the radio frequency ablation instrument (200).
5. A method of measurement and control of a radio frequency ablation measurement and control system according to any of claims 1-4, comprising the following steps: the main needle (110) of the radio frequency ablation needle (100) is designated as a temperature control element by the radio frequency ablation instrument (200) so as to adjust the working parameters of the radio frequency ablation instrument (200), and the sub-needles (120) of the radio frequency ablation needle (100) are designated as the temperature control element so as to adjust the working parameters of the radio frequency ablation instrument (200).
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109481013A (en) * | 2018-12-19 | 2019-03-19 | 南京康友医疗科技有限公司 | A kind of microwave ablation device with thermal field monitoring function |
| CN109498155A (en) * | 2019-01-10 | 2019-03-22 | 上海交通大学 | Quick planning system and method in ablation art |
| CN114052894A (en) * | 2021-11-18 | 2022-02-18 | 上海睿速创生医疗科技有限公司 | Multi-electrode radio frequency ablation needle |
| CN115444551A (en) * | 2022-11-11 | 2022-12-09 | 海杰亚（北京）医疗器械有限公司 | Radio frequency ablation electrode needle |
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| CN109481013A (en) * | 2018-12-19 | 2019-03-19 | 南京康友医疗科技有限公司 | A kind of microwave ablation device with thermal field monitoring function |
| CN109498155A (en) * | 2019-01-10 | 2019-03-22 | 上海交通大学 | Quick planning system and method in ablation art |
| CN114052894A (en) * | 2021-11-18 | 2022-02-18 | 上海睿速创生医疗科技有限公司 | Multi-electrode radio frequency ablation needle |
| CN115444551A (en) * | 2022-11-11 | 2022-12-09 | 海杰亚（北京）医疗器械有限公司 | Radio frequency ablation electrode needle |
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