CN116500248A - Pathological section scanning device and method - Google Patents
Pathological section scanning device and method Download PDFInfo
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Abstract
The invention discloses a pathological section scanning device and a pathological section scanning method, and belongs to the technical field of medical detection. The device comprises a control module, an analysis processing module, a feedback module, a display module, a storage module, a transmission module, a scanning assembly, a fixing assembly and an anti-shake assembly, wherein the analysis processing module, the feedback module, the display module, the storage module and the transmission module are in communication connection with the control module; the scanning component scans pathological section images and transmits the pathological section images to the control module; the anti-shake assembly detects vibration generated in the process that the scanning assembly focuses on pathological sections and transmits the vibration to the control module, and the control module drives the fixing assembly to fix the scanning assembly. The scanning definition is prevented from being influenced by vibration generated when the guide rail rapidly moves to focus, so that the scanning image is unclear to cause misdiagnosis, and the scanning precision and the scanning efficiency are improved.
Description
Technical Field
The invention relates to the technical field of medical detection, in particular to a pathological section scanning device and a pathological section scanning method.
Background
Pathological section is a medical means widely used in the medical field, pathological section is made by pathological histology method (usually, pathological section is embedded in paraffin block, sliced by slicer, then hematoxylin-eosin (H-E) staining is used), the occurrence and development process of pathological section is further checked by microscope, finally pathological diagnosis is made. The preparation method is characterized in that when in preparation, part of pathological tissues or organs are subjected to treatment by various chemicals and burying methods, so that the pathological tissues or organs are fixed and hardened, are cut into slices on a slicing machine, are adhered to a glass slide, are dyed with various colors for examination under a microscope to observe pathological changes, and are used for making pathological diagnosis, thereby providing assistance for clinical diagnosis and treatment.
In the early stage, pathology analysis workers generally observe slice tissues on a glass slide through a microscope, and fatigue is easily generated by observing the slice tissues through an eyepiece of the microscope, so that time and labor are often wasted, the traditional physical glass slide is not very accurate, a new generation digital pathology slice is required to be converted, a digital pathology scanning system is indispensable, a digital image technology is combined with a traditional optical amplifying device, and the physical slice is scanned and converted into a digital image, so that a film reading mode is more convenient, and a foundation is laid for remote consultation, pathology teaching and digital storage of the slice.
In the prior art, a pathological section scanning device basically loads a glass slide on an X-axis horizontal moving platform and a Y-axis horizontal moving platform, a scanning mirror moves up and down along a Z-axis to focus and scan and shoot pictures, the glass slide is easy to shake in the moving process of an X-axis guide rail and a Y-axis guide rail in the focusing process, and vibration is easy to generate when the glass slide moves to focus rapidly, so that the scanning definition of the scanning mirror is influenced.
Disclosure of Invention
The invention aims to provide a pathological section scanning device and a pathological section scanning method, which are used for solving the problem that the scanning definition is affected by vibration easily generated when a scanning mirror of the pathological section scanning device is rapidly moved and focused by a guide rail in the prior art.
The aim of the invention can be achieved by the following technical scheme:
the pathological section scanning device comprises a control module, an analysis processing module, a feedback module, a display module, a storage module and a transmission module which are in communication connection with the control module, and also comprises a scanning assembly, a fixing assembly and an anti-shake assembly which are in communication connection with the control module; the scanning component scans pathological section images and transmits the pathological section images to the control module; the anti-shake assembly detects vibration generated in the process that the scanning assembly focuses on pathological sections and transmits the vibration to the control module, and the control module drives the fixing assembly to fix the scanning assembly.
As a further scheme of the invention, the device also comprises a positioning component, wherein the positioning component drives the scanning component to focus pathological sections; the scanning assembly comprises a scanning mirror, an installation seat and a positioning mirror, one end of the positioning mirror penetrates through the installation seat to be connected to the positioning assembly, the scanning mirror is installed on the bottom surface of the installation seat, and the positioning mirror is installed on the bottom wall of the installation seat.
As a further scheme of the invention, the anti-shake component is sleeved on the side wall of the scanning mirror; the anti-shake assembly comprises a vibration sensor and a current detection assembly; the vibration sensor comprises a lug, a stirrup, a magnetic field assembly and an electric wire; the stirrup and the wire form a closed loop; the lug is attached to the side wall of the scanning mirror, the stirrup plate is hinged to the bottom of the lug, and vibration transmitted by the scanning assembly is received to generate swing; the magnetic field assembly is arranged on the inner wall of the vibration sensor and forms a magnetic field covering the closed loop, and the current detection assembly detects current generated by the closed loop.
As a further scheme of the invention, the vibration sensor further comprises a receiving film, wherein the receiving film is sleeved on the side wall of the scanning mirror; the lug is buried in the receiving film, and the bottom of the lug protrudes out of the receiving film.
As a further scheme of the invention, the anti-shake assembly further comprises a vibration absorbing assembly, and the vibration absorbing assembly is arranged at the top of the vibration sensor; the vibration absorbing assembly comprises a shell and an air spring, the shell is sleeved on the side wall of the scanning mirror, and the inner wall of the shell is connected with the side wall of the scanning mirror through the air spring; the shell is made of magnesium alloy or cast iron.
As a further scheme of the invention, the device further comprises a base, wherein the base is provided with a scanning port, the scanning port is provided with a carrying box, the carrying box comprises a box body, the top of the box body is provided with a clamping groove, and the clamping groove is matched with a glass slide for fixing pathological sections.
As a further scheme of the invention, the device further comprises a transmission assembly, a plurality of object carrying boxes are uniformly arranged on the transmission assembly, a transmission channel is arranged on the base, the transmission assembly transmits the object carrying boxes with pathological sections clamped to the scanning port along the transmission channel for scanning, the scanning port is provided with a photoelectric sensing probe, and the photoelectric sensing probe is electrically connected with the transmission assembly.
As a further aspect of the present invention, the fixing assembly includes a mechanical claw, a first clamping plate, a spring, and a second clamping plate, wherein the mechanical claw is fixed on the base, the first clamping plate is fixed on a side claw wall of the mechanical claw, and the second clamping plate is connected with the first clamping plate through the spring.
A pathological section scanning method, comprising the steps of:
s1: sequentially placing a plurality of pathological sections into a plurality of carrying boxes, starting a transmission assembly, conveying the pathological sections to a scanning port by the transmission assembly, and controlling the transmission assembly to be suspended when the photoelectric sensing probe senses that the carrying boxes pass through;
s2: the control module determines the pathological section position according to the image information acquired by the positioning mirror and controls the positioning assembly to drive the scanning mirror to focus the pathological section;
s3: the anti-shake assembly detects scanning mirror vibration: if the scanning mirror vibrates, the lug receives vibration generated by the scanning mirror and transmits the vibration to the stirrup plate, so that the stirrup plate swings, a magnetic induction line in a closed loop cutting magnetic field generates current, and a current detection assembly detects a current signal generated by the closed loop and transmits the current signal to the control module; the control module controls the fixing component to clamp and fix the scanning mirror;
s4: the control module controls the scanning mirror to scan the pathological section, obtains graphic information of the pathological section, transmits the graphic information to the analysis processing module for analysis processing, screens out the pathological section meeting the requirements and stores the pathological section in the storage module;
s5: the control module controls the transmission assembly to continue to operate, and scans the next pathological section.
As a further aspect of the present invention, step S4 includes the steps of:
a1: the analysis processing module cuts the scanned pathological section image according to preset pixels and judges whether the cut pathological section pixels are smaller than the preset pixels or not;
a2: if the cut pathological section pixels are smaller than the preset pixels, creating a blank picture, wherein the pixels of the blank picture are equal to the preset pixels, and the analysis processing module patches the pathological section which is smaller than the preset pixels on the blank picture, and the storage module stores the patched blank picture;
a3: if the cut pathological section pixels are equal to the preset pixels, the storage module directly stores the pictures of the cut pathological section;
a4: the analysis processing module analyzes and splices the patched blank picture and the cut pathological section which is equal to the preset pixel, scans the analyzed and spliced pathological section, generates a pathological section integral picture and stores the pathological section integral picture in the storage module.
The invention has the beneficial effects that:
(1) According to the pathological section scanning device and method disclosed by the invention, the pathological section image is scanned by the scanning component and transmitted to the control module, the positioning component drives the scanning component to focus the pathological section, the vibration generated by the scanning component is detected and absorbed by the anti-shake component, the scanning component is fixed by the fixing component, the phenomenon that the scanning definition is affected by vibration generated by the scanning mirror when the guide rail moves rapidly for focusing is avoided, the scanning image is unclear and misdiagnosis is caused, and the scanning precision is improved.
(2) The invention discloses a pathological section scanning device and a pathological section scanning method, wherein a vibration sensor is sleeved on the side wall of a scanning mirror and used for detecting whether the scanning mirror vibrates, if the scanning mirror vibrates, a closed loop is formed by a stirrup plate and an electric wire to generate current, a control module controls a fixing component to clamp the scanning mirror after detecting the current generated by the closed loop, the scanning mirror is prevented from continuously shaking, and after the scanning mirror is clamped by the fixing component, the scanning of pathological sections is performed, so that the acquired pathological section images are ensured to be clearer, misdiagnosis caused by unclear pathological section image information is avoided, and the scanning efficiency is improved.
Drawings
The invention is further described below with reference to the accompanying drawings.
Fig. 1 is a schematic diagram of the overall structure of a pathological section scanning device according to the present invention;
fig. 2 is a schematic diagram of an internal structure of a shock absorbing assembly of a pathological section scanning device according to the present invention;
FIG. 3 is a top view of a vibration sensor of a pathological section scanning device according to the present invention;
fig. 4 is a schematic diagram of an internal structure of a vibration sensor of a pathological section scanning device according to the present invention;
fig. 5 is a schematic diagram of the overall structure of a carrying case of the pathological section scanning device according to the present invention.
In the figure: 1. a scanning assembly; 101. a scanning mirror; 102. a mounting base; 103. a positioning mirror; 2. a positioning assembly; 3. a fixing assembly; 301. a mechanical claw; 302. a first clamping plate; 303. a spring; 304. a second clamping plate; 306. a fixing frame; 4. a transmission assembly; 5. a scanning port; 6. a carrying box; 601. a case body; 602. a clamping groove; 7. a base; 8. an anti-shake assembly; 81. a shock absorbing assembly; 811. a housing; 812. an air spring; 82. a vibration sensor; 821. a receiving film; 822. a bump; 823. a stirrup; 824. a first magnetic pole; 825. a second magnetic pole; 826. an electric wire; 20. a mounting frame; 21. an X-axis transmission assembly; 211. an X-axis servo cylinder; 212. a slideway; 213. a chute; 214. a connecting block; 215. a slide block; 22. a Y-axis transmission assembly; 221. a ball screw assembly; 222. a slide; 23. a Z-axis transmission assembly; 231. a Z-axis servo cylinder; 9. a photoelectric sensing probe; 10. and (5) damping glue nails.
Detailed Description
The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments, and all other embodiments obtained by those skilled in the art without making creative efforts based on the embodiments of the present invention are included in the protection scope of the present invention.
1-5, the pathological section scanning device comprises a control module, an analysis processing module, a feedback module, a display module, a storage module, a transmission module, a scanning component 1, a positioning component 2, a fixing component 3 and an anti-shake component 8, wherein the analysis processing module, the feedback module, the display module, the storage module, the transmission module, the scanning component 1, the fixing component 3 and the anti-shake component 8 are respectively in communication connection with the control module; the scanning assembly 1 is used for scanning pathological section image information and transmitting the pathological section image information to the control module, the control module transmits the obtained pathological section image information to the analysis processing module, and the analysis processing module screens out pathological sections meeting the requirements from the scanned pathological section image and stores the pathological section image information in the storage module; the display module is used for displaying a slice analysis process image and a quantitative analysis index report of the digital slice image slice processing analysis of the analysis processing module; the feedback module is connected with the analysis processing module and is used for feeding back and inputting analysis processing result information to the analysis processing module, and the analysis processing module carries out self-correction data update according to the analysis processing result information; the storage module is used for storing the picture information of the pathological section meeting the requirements, and the transmission module is used for carrying out data interaction on the information stored in the storage module and an external database; the positioning component 2 is used for driving the scanning component 1 to focus the pathological section; the anti-shake assembly 8 is used for detecting and absorbing vibration generated by the scanning assembly 1; the fixing component 3 fixes the scanning component 1 to prevent jitter from affecting focusing.
Since the existing pathological section scanning device focuses the pathological section by moving the glass slide positioned in the X-axis and Y-axis directions, the glass slide is easy to cause shaking of the scanning mirror 101 in the process of moving the glass slide on the guide rail rapidly, so that the scanned image of the scanning mirror 101 is blurred to influence the subsequent pathological analysis, the scanning mirror 101 is required to be not shaking when scanning is performed at the moment, the scanning can be started after the line of sight is clear, the efficiency is low, in order to improve the scanning efficiency, the positioning assembly 2 is arranged to drive the scanning assembly 1 to focus the pathological section for scanning, the positioning assembly 2 comprises the mounting frame 20, the mounting frame 20 is arranged on the base 7, shock absorption glue nails 10 are nailed at the connecting positions between the connecting frames of the mounting frame 20 and the base 7, the shock absorption glue nails 10 are used for buffering and damping by utilizing the elasticity and the damping effect of rubber, the energy when the load shaking can be consumed by the rubber, the stress is eliminated, and the vibration on the mounting frame 20 is slowed down;
an X-axis transmission assembly 21, a Y-axis transmission assembly 22 and a Z-axis transmission assembly 23 are arranged on the mounting frame 20, the X-axis transmission assembly 21 drives the scanning assembly 1 to move along the X-axis direction, the Y-axis transmission assembly 22 drives the scanning assembly 1 to move along the Y-axis direction, the Z-axis transmission assembly 23 drives the scanning assembly 1 to move along the Z-axis direction, and the driving directions of the X-axis transmission assembly 21, the Y-axis transmission assembly 22 and the Z-axis transmission assembly 23 are mutually perpendicular;
the mounting frame 20 is of a square frame structure, in a square frame formed at the top of the mounting frame 20, X-axis transmission assemblies 21 are mounted on the mounting frame 20 bars on two opposite sides of the mounting frame 20, Y-axis transmission assemblies 22 are connected between the two X-axis transmission assemblies 21, Z-axis transmission assemblies 23 are perpendicular to the Y-axis transmission assemblies 22, and the scanning assembly 1 is mounted at the end part of the Z-axis transmission assemblies 23;
in an embodiment, the X-axis transmission assembly 21 includes an X-axis servo cylinder 211, a slide way 212, a slide way 213, a connection block 214 and a sliding block 215, the slide way 212 is connected below the rod of the mounting frame 20, the slide way 213 is arranged in the slide way 212, the sliding block 215 is slidingly connected to the rod of the mounting frame 20, one side of the connection block 214 is connected to the bottom of the sliding block 215, the other side of the connection block 214 protrudes out of the slide way 213 to be abutted to the outer bottom wall of the slide way 212, the part of the connection block 214 protruding out of the slide way 213 is connected with the piston rod of the X-axis servo cylinder 211, the connection block 214 is driven to move by extending or retracting the piston rod of the X-axis servo cylinder 211, the connection block 214 slides along the slide way 213, and the sliding block 215 slides along the rod of the mounting frame 20 under the driving of the connection block 214; in the process of synchronously moving the left X-axis transmission component 21 and the right X-axis transmission component 21, the scanning component 1 is driven to move along the X-axis direction to adjust the position of the scanning component 1 for focusing pathological sections;
in an embodiment, the Y-axis transmission assembly 22 includes a ball screw assembly and a sliding seat 222, the sliding seat 222 is connected to the ball screw assembly 221, the ball screw assembly drives the screw to rotate through a servo motor to drive the sliding seat 222 to move, so that the scanning assembly 1 is driven by the Y-axis transmission assembly 22 to move along the Y-axis direction to adjust the position of the scanning assembly 1 focusing on the pathological section;
in one embodiment, the Z-axis transmission assembly 23 includes a Z-axis servo cylinder 231, the Z-axis servo cylinder 231 is connected to the slide base 222, and a piston rod of the Z-axis servo cylinder 231 extends through the slide base 222 to below the slide base 222 and is connected with the scanning assembly 1; the scanning assembly 1 is adjusted to move to focus the pathological section along the Z-axis direction by the extension or shortening of the piston rod of the Z-axis servo cylinder 231;
the control module adjusts the horizontal position of the scanning mirror 101 along the X-axis direction and the Y-axis direction by controlling the X-axis transmission assembly 21 and the Y-axis transmission assembly 22 according to the pathological section position detected by the positioning mirror 103, and adjusts the height of the scanning mirror 101 by controlling the Z-axis transmission assembly 23, so that the scanning assembly 1 moves more stably in the process of focusing the pathological section, the shaking degree of the scanning mirror 101 caused by the vibration of the mounting frame 20 is reduced, and the pathological section is focused accurately.
The scanning assembly 1 comprises a scanning mirror 101, a mounting seat 102 and a positioning mirror 103, wherein the upper end part of the scanning mirror 101 penetrates through the mounting seat 102 and is connected to a piston rod of a Z-axis servo cylinder 231, the positioning mirror 103 is arranged on the mounting seat 102 and surrounds the side wall of the scanning mirror 101, the positioning mirror 103 is used for positioning the positioning assembly 2 to adjust the position of a pathological section of the scanning mirror 101 in focusing, a control module controls an X-axis transmission assembly 21 and a Y-axis transmission assembly 22 to adjust the position of the pathological section of the scanning mirror 101 in focusing through the pathological section image position obtained by the positioning mirror 103, and the height of the scanning mirror 101 is adjusted through the extension or shortening of the piston rod of the Z-axis servo cylinder 231 so that the image of the pathological section of the scanning mirror 101 in scanning is clearer.
Since the scanning mirror 101 moves to align the pathological section, slight shake still exists, even slight shake can cause pathological section image blurring of scanning mirror 101 scanning, once pathological section image blurring, misdiagnosis can be caused if a pathological section is located in a blurring area, medical accidents are caused, an anti-shake assembly 8 is installed on the scanning mirror 101, and the residual tiny vibration is detected and absorbed, the anti-shake assembly 8 comprises a vibration sensor 82 sleeved on the side wall of the scanning mirror 101, the vibration sensor 82 comprises a receiving film 821, a protruding block 822, a stirrup 823, a first magnetic pole 824, a second magnetic pole 825 and an electric wire 826, the receiving film 821 is made of silicon rubber, the receiving film 821 is sleeved on the side wall of the scanning mirror 101, the protruding block 822 is buried in the receiving film 821, one side wall of the protruding block 822 is tightly attached to the side wall of the scanning mirror 101, the bottom end of the protruding block 822 is hinged with the receiving film 821, a first magnetic pole 824 and a second magnetic pole 825 are respectively fixed on two opposite sides of the first magnetic pole 823 and the second magnetic pole 823, a magnetic pole 823 is formed between the first magnetic pole 824 and the second magnetic pole 823, the first magnetic pole 823 and the second magnetic pole 823 and the electric wire 823 are connected with the stirrup 823 in a closed loop, and the magnetic field stirrup 823 is formed; the receiving film 821 is sleeved on the side wall of the scanning mirror 101, the receiving film 821 is used for collecting vibration caused by shaking generated by the scanning mirror 101, the vibration received by the receiving film 821 can cause the film surface resonance of the receiving film 821 in the process of transversely transmitting the vibration along the cross section of the receiving film 821, so that the film surface of the receiving film 821 transmits the vibration together, the vibration is amplified, the lug 822 senses the vibration to vibrate, the stirrup 823 hinged to the bottom of the lug 822 swings along with the vibration of the lug 822, the stirrup 823 is positioned in a magnetic field, a magnetic induction line in the magnetic field is cut in the swinging process of the stirrup 823, a closed loop is formed by the stirrup 823 and an electric wire 826, and a current detection component is connected in series, and is used for detecting whether current is generated in the closed loop, the control module controls the fixing component 3 to clamp the scanning mirror 101 after detecting the current generated by the closed loop, the scanning mirror 101 is prevented from continuing shaking, the obtained pathological section image is ensured to be clearer after the scanning of the pathological section is clamped by the fixing component 3, and the pathological section image information is prevented from being misdiagnosed.
In one embodiment, the current detecting assembly comprises a light tube and a photoreceptor, wherein the light tube is connected in series in a closed loop formed by the stirrup 823 and the electric wire 826, the photoreceptor which is connected with the control module in a communication way is arranged in the vibration sensor 82 and is used for sensing the brightness of light rays in the vibration sensor 82, when the protrusion 822 is vibrated to enable the stirrup 823 to swing in a magnetic field to cut the magnetic induction wire to generate current, the light tube is electrified to emit light, the photoreceptor senses the brightness emitted by the light, the detected light signal is transmitted to the control module, and the control module controls the fixing assembly 3 to clamp the scanning mirror 101, so that the scanning definition is prevented from being affected by shaking of the scanning mirror 101.
In an embodiment, the fixed component 3 is provided with an inductive switch, the mechanical claw 301 is provided with an electromagnetic relay, the electromagnetic relay is connected in series in the closed loop, the inductive switch is in communication connection with the control module, if the inductive switch is in an open state, the fixed component 3 can not operate, the mechanical claw 301 can clamp the scanning mirror 101 only after the inductive switch is closed and the moving and static contacts of the electromagnetic relay are connected, when the control module controls the positioning component 2 to drive the scanning component 1 to move to focus a pathological section, the control module controls the inductive switch to be closed, the current detection component comprises a lamp tube and a photoresistor, when the closed loop generates current, the lamp tube emits light, the photoresistor is in a high-resistance state, when the photoresistor senses light, the resistance value of the photoresistor is reduced, the photoresistor is in circuit connection, so that an armature of the electromagnetic relay is adsorbed by magnetic force generated after the coil in the electromagnetic relay is electrified, the moving and the static contacts are connected, the mechanical claw 301 clamps the scanning mirror 101, and if the control module controls the inductive switch to be disconnected in the process of positioning the next pathological section, even if the stirrup 823 swings to generate current, the mechanical claw 301 can not operate.
In an embodiment, in order to reduce the vibration generated by the mounting frame 20 during the process of driving the scanning assembly 1 by the positioning assembly 2 to move and focus the pathological section to affect the positioning and focusing of the scanning assembly 1, a vibration absorbing assembly 81 is installed above the vibration sensor 82, the vibration absorbing assembly 81 is sleeved on the side wall of the scanning mirror 101, the vibration absorbing assembly 81 comprises a shell 811 and an air spring 812, the shell 811 is sleeved on the side wall of the scanning mirror 101, the inner side wall of the shell 811 is connected with the side wall of the scanning mirror 101 through a plurality of air springs 812, the air spring 812 is filled with a sealed air column, when the side wall of the scanning mirror 101 vibrates, the elastic characteristic of the air spring column is utilized, after the vibration force received by the side wall of the scanning mirror 101 is transmitted to the air spring 812, the side connected with the air spring 812 receives an impact force, the impact force compresses air, and the side connected with the air spring 812 and the shell 811 is kept relatively static due to inertia, and the impact force of the vibration is compressed and absorbed after passing through the sealed air column of the air spring 812, so that the vibration is weakened and absorbed gradually, the vibration disappears quickly, and the vibration is prevented from waiting for complete disappearance of the vibration, and the scanning efficiency is improved;
in one embodiment, in order to further improve the vibration absorbing effect of the vibration absorbing member 81, the housing 811 is a shell made of magnesium alloy or cast iron having excellent performance of absorbing vibration energy, thereby improving the vibration absorbing effect of the vibration absorbing member 81.
In an embodiment, since after the scan mirror 101 focuses on the pathological section, it cannot be determined whether the vibration negative effect inside the scan mirror 101 is eliminated, if the image information obtained by scanning the pathological section is easy to cause the image to be blurred, the closed loop where the stirrup 823 is located cuts the magnetic induction line in the magnetic field to generate current, the current flows through the light tube to make the light tube emit light, and the control system determines whether the scan mirror 101 is still vibrating by detecting whether the light tube emits light through the photoreceptor, because the stirrup 823 swings to cut the magnetic induction line to make the light tube emit light as long as the scan mirror 101 vibrates, if the light tube does not emit light, the control module controls the scan mirror 101 to scan, if the light tube emits light, the control module controls the fixing component 3 to clamp the scan mirror 101 to prevent the scan mirror from continuing vibrating, thereby controlling the scan mirror 101 to scan, accurately determining whether the scan mirror 101 vibrates, ensuring that the scanned pathological section image is clear, and improving the scanning efficiency.
In an embodiment, when the positioning component 2 drives the scanning component 1 to focus the pathological section, and the scanning component 2 is required to drive the scanning component 1 to focus the pathological section when the scanning component 1 needs to scan and pick up a proper position for scanning analysis, a user observes whether the position is suitable for scanning from the scanning mirror 101, but each time the positioning component 2 drives the scanning component 1 to move, the scanning mirror 101 vibrates, even if the vibration slightly causes the blurring of images in the scanning mirror 101, the focusing definition needs to be refocused, the existence of the vibration influences the focusing definition, so that the position needs to be observed again after the vibration disappears when focusing, the position is suitable for scanning, the user does not need to move to the next position and continues to wait until the vibration disappears, the working efficiency is low, in order to prevent the focusing efficiency from being influenced by vibration, an anti-shake assembly 8 is arranged on the side wall of a scanning mirror 101, when the scanning mirror 101 vibrates, the vibration of the scanning mirror 101 is transmitted to a lug 822 attached to the side wall of the scanning mirror 101 to cause resonance of the lug 822, the vibration of the lug 822 can cause swinging of a stirrup 823 hinged to the bottom of the lug 822, a closed loop formed by the stirrup 823 and a wire 826 is in a magnetic field coverage range, when the swinging of the stirrup 823 can cut a magnetic induction wire to generate current in the closed loop, at the moment, a current signal generated in the closed loop is detected by a current detection assembly and then transmitted to a control module, and the control module drives a fixing assembly 3 to clamp the scanning mirror 101 to stop vibrating the scanning mirror 101, and meanwhile, the vibration absorption assembly 81 absorbs residual vibration; if the vibration disappears, the stirrup 823 does not swing, the current detection component does not detect that current exists in the closed loop, and the control module controls the fixing component 3 to loosen the scanning mirror 101, so that the scanning mirror 101 can move continuously for focusing; if the scanning mirror 101 does not vibrate, the stirrup 823 continues to swing slightly due to the inertia force to generate current, the fixing component 3 continues to clamp the scanning mirror 101 to fix, and at this time, if the scanning mirror 101 finishes scanning the area and needs to move, the control module can be manually operated to control the fixing component 3 to loosen the clamping and fixing of the scanning mirror 101.
The scanning assembly 1, the positioning assembly 2, the fixing assembly 3 and the anti-shake assembly 8 are arranged on the base 7, the scanning opening 5 is formed in the base 7, the scanning opening 5 is provided with the carrying box 6, the carrying box 6 comprises a box body 601, a clamping groove 602 is formed in the top of the box body 601, the clamping groove 602 is matched with a slide glass for fixing pathological sections, and the slide glass for fixing the pathological sections is placed in the clamping groove 602 for scanning;
the existing pathological section is placed on the base 7 for focusing scanning, manual placement is often needed, one pathological section is removed after being scanned and placed on the other pathological section, efficiency is low, in order to improve detection efficiency, the transmission assembly 4 is arranged, a plurality of object carrying boxes 6 are uniformly distributed on the transmission assembly 4, the base 7 is provided with a conveying channel, the transmission assembly 4 conveys the object carrying boxes 6 which clamp the pathological section along the conveying channel to the scanning port 5 for scanning, the scanning port 5 is provided with the photoelectric sensing probe 9, and the photoelectric sensing probe 9 is electrically connected with the transmission assembly 4;
in an embodiment, a plurality of carrying boxes 6 are placed on the conveyor belt of the transmission assembly 4 at equal intervals, after the carrying boxes 6 on the conveyor belt pass through the photoelectric sensing probe 9, the conveyor belt is controlled to stop transmitting when the light of the photoelectric sensing probe 9 is blocked, the control module controls the positioning assembly 2 to position so that the scanning assembly 1 scans the pathological section in focus, and the control module controls the conveyor belt to continue to operate after the scanning is completed, so that the pathological section is prevented from being placed manually, and the detection efficiency is improved.
The fixed component 3 comprises a mechanical claw 301, a first clamping plate 302, a spring 303 and a second clamping plate 304, wherein the mechanical claw 301 is arranged on the base 7 through a fixing frame 306, the first clamping plate 302 is fixed on one side claw wall of the mechanical claw 301, the second clamping plate 304 is connected with the first clamping plate 302 through the spring 303, the first clamping plate 302 and the second clamping plate 304 are connected through the spring 303, clamping force is increased, the mechanical claw 301 is prevented from being directly contacted with the scanning mirror 101, and the clamped scanning mirror 101 can be prevented from slipping, friction is reduced, so that clamping is firmer;
in an embodiment, a protective soft cushion is installed on the side, attached to the scanning mirror 101, of the second clamping plate 304 to protect the scanning mirror 101 from scratch and damage, when the scanning mirror 101 vibrates, the stirrup 823 swings in a magnetic field to cut a magnetic induction line to generate current, the control module drives the mechanical claw 301 to start clamping the scanning mirror 101 to keep the scanning mirror from continuously shaking after detecting the current, when the scanning mirror 101 does not vibrate any more, no current passes through the circuit, the mechanical claw 301 loosens the scanning mirror 101, and then scanning of the next pathological section is performed.
The invention discloses a pathological section scanning device, which has the following working principle:
the vibration sensor 82 is sleeved on the side wall of the scanning mirror 101 and is used for detecting whether the scanning mirror 101 vibrates, the receiving film 821 is made of silicon rubber, the receiving film 821 is sleeved on the side wall of the scanning mirror 101, the lug 822 is embedded in the receiving film 821, one side wall of the lug 822 is clung to the side wall of the scanning mirror 101, the bottom end of the lug 822 protrudes out of the receiving film 821 and is hinged with the stirrup 823, a first magnetic pole 824 and a second magnetic pole 825 are respectively fixed on two opposite sides of the stirrup 823, a magnetic field is formed between the first magnetic pole 824 and the second magnetic pole 825, the stirrup 823 is located in the coverage of the magnetic field, and the stirrup 823 is connected with the electric wire 826 to form a closed loop; the receiving film 821 is sleeved on the side wall of the scanning mirror 101, the receiving film 821 is used for collecting vibration caused by shaking generated by the scanning mirror 101, the vibration received by the receiving film 821 can cause resonance of the film surface of the receiving film 821 in the process of transversely transmitting the vibration along the cross section of the receiving film 821, so that the film surface of the receiving film 821 transmits the vibration together, the vibration is amplified, the lug 822 senses the vibration to vibrate, the stirrup 823 hinged to the bottom of the lug 822 swings along with the vibration of the lug 822, the stirrup 823 is positioned in a magnetic field, when the stirrup 823 swings, a closed loop is formed by the stirrup 823 and an electric wire 826 to generate current, the control module controls the fixing component 3 to clamp the scanning mirror 101 after detecting the current generated by the closed loop, the scanning mirror 101 is prevented from continuously shaking, the scanning of a pathological section is carried out after the fixing component 3 clamps the scanning mirror 101, the obtained pathological section image is ensured to be clearer, and misdiagnosis caused by unclear image information of the pathological section is avoided.
In order to avoid misdiagnosis caused by unclear view of a lesion area due to distortion and blurring of an obtained pathological section image, and to ensure that the scanned pathological section image is clear, a pathological section scanning method for the pathological section scanning device comprises the following steps of:
s1: sequentially placing a plurality of pathological sections into a plurality of carrying boxes 6, starting a transmission assembly 4, conveying the pathological sections to a scanning port 5 by the transmission assembly 4, and controlling the transmission assembly 4 to be suspended when a photoelectric sensing probe 9 senses that the carrying boxes 6 pass through;
s2: the control module determines the pathological section position according to the image information acquired by the positioning mirror 103 and controls the positioning assembly 2 to drive the scanning mirror 101 to focus the pathological section;
s3: the anti-shake component 8 detects vibration generated after the scanning mirror 101 moves to the position right above the pathological section through the vibration sensor 82 and controls the fixing component 3 to clamp and fix the scanning mirror 101;
s4: the control module controls the scanning mirror 101 to scan the pathological section, obtains graphic information of the pathological section, transmits the graphic information to the analysis processing module for analysis processing, screens out the pathological section meeting the requirements, and stores the pathological section in the storage module, wherein the analysis processing module cuts the scanned pathological section image according to preset pixels and judges whether the cut pathological section pixels are smaller than the preset pixels; if the cut pathological section pixels are smaller than the preset pixels, creating a blank picture, wherein the pixels of the blank picture are equal to the preset pixels, and the analysis processing module patches the pathological section which is smaller than the preset pixels on the blank picture, and the storage module stores the patched blank picture; if the cut pathological section pixels are equal to the preset pixels, the storage module directly stores the pictures of the cut pathological section; the analysis processing module analyzes and splices the patched blank picture and the cut pathological section which is equal to the preset pixel, scans the analyzed and spliced pathological section, generates a pathological section integral picture and stores the pathological section integral picture in the storage module;
s5: the control module controls the transmission assembly 4 to continue to run, and the steps are repeated to scan the next pathological section.
While certain embodiments of the present invention have been described in detail, this disclosure is only for the purpose of illustrating preferred embodiments of the invention and is not to be construed as limiting the scope of the invention. All equivalent changes and modifications within the scope of the present invention are intended to be covered by the present invention.
Claims (8)
1. The pathological section scanning device comprises a control module, an analysis processing module, a feedback module, a display module, a storage module and a transmission module which are in communication connection with the control module, and is characterized by also comprising a scanning component, a fixing component and an anti-shake component which are in communication connection with the control module; the scanning component scans pathological section images and transmits the pathological section images to the control module; the anti-shake component detects vibration generated in the process of focusing the pathological section by the scanning component and transmits the vibration to the control module, and the control module drives the fixing component to fix the scanning component; the positioning assembly drives the scanning assembly to focus the pathological section; the scanning assembly comprises a scanning mirror, an installation seat and a positioning mirror, one end of the positioning mirror penetrates through the installation seat and is connected to the positioning assembly, the scanning mirror is installed on the bottom surface of the installation seat, and the positioning mirror is installed on the bottom wall of the installation seat; the anti-shake assembly is sleeved on the side wall of the scanning mirror; the anti-shake assembly comprises a vibration sensor and a current detection assembly; the vibration sensor comprises a lug, a stirrup, a magnetic field assembly and an electric wire; the stirrup and the wire form a closed loop; the lug is attached to the side wall of the scanning mirror, the stirrup plate is hinged to the bottom of the lug, and vibration transmitted by the scanning assembly is received to generate swing; the magnetic field assembly is arranged on the inner wall of the vibration sensor and forms a magnetic field covering the closed loop, and the current detection assembly detects current generated by the closed loop.
2. The pathological section scanning device of claim 1, wherein the vibration sensor further comprises a receiving film, the receiving film being sleeved on the side wall of the scanning mirror; the lug is buried in the receiving film, and the bottom of the lug protrudes out of the receiving film.
3. The pathological section scanning device of claim 1, wherein the anti-shake assembly further comprises a shock absorbing assembly mounted on top of the vibration sensor; the vibration absorbing assembly comprises a shell and an air spring, the shell is sleeved on the side wall of the scanning mirror, and the inner wall of the shell is connected with the side wall of the scanning mirror through the air spring; the shell is made of magnesium alloy or cast iron.
4. The pathological section scanning device according to claim 1, further comprising a base, wherein the base is provided with a scanning port, the scanning port is provided with a carrying box, the carrying box comprises a box body, the top of the box body is provided with a clamping groove, and the clamping groove is matched with a glass slide for fixing the pathological section.
5. The pathological section scanning device according to claim 4, further comprising a transmission assembly, wherein a plurality of the object carrying boxes are uniformly arranged on the transmission assembly, the base is provided with a transmission channel, the transmission assembly carries the object carrying boxes holding pathological sections along the transmission channel to the scanning port for scanning, the scanning port is provided with a photoelectric sensing probe, and the photoelectric sensing probe is electrically connected with the transmission assembly.
6. The pathological section scanning device according to claim 4, wherein the fixing assembly comprises a gripper, a first clamping plate, a spring and a second clamping plate, the gripper is fixed on the base, the first clamping plate is fixed on a side wall of the gripper, and the second clamping plate is connected with the first clamping plate through the spring.
7. A pathological section scanning method for a pathological section scanning apparatus as claimed in any one of claims 1 to 6, comprising the steps of:
s1: sequentially placing a plurality of pathological sections into a plurality of carrying boxes, starting a transmission assembly, conveying the pathological sections to a scanning port by the transmission assembly, and controlling the transmission assembly to be suspended when the photoelectric sensing probe senses that the carrying boxes pass through;
s2: the control module determines the pathological section position according to the image information acquired by the positioning mirror and controls the positioning assembly to drive the scanning mirror to focus the pathological section;
s3: the anti-shake assembly detects scanning mirror vibration: if the scanning mirror vibrates, the lug receives vibration generated by the scanning mirror and transmits the vibration to the stirrup plate, so that the stirrup plate swings, a magnetic induction line in a closed loop cutting magnetic field generates current, and a current detection assembly detects a current signal generated by the closed loop and transmits the current signal to the control module; the control module controls the fixing component to clamp and fix the scanning mirror;
s4: the control module controls the scanning mirror to scan the pathological section, obtains graphic information of the pathological section, transmits the graphic information to the analysis processing module for analysis processing, screens out the pathological section meeting the requirements and stores the pathological section in the storage module;
s5: the control module controls the transmission assembly to continue to operate, and scans the next pathological section.
8. The pathological section scanning method according to claim 7, wherein the step S4 comprises the steps of:
a1: the analysis processing module cuts the scanned pathological section image according to preset pixels and judges whether the cut pathological section pixels are smaller than the preset pixels or not;
a2: if the cut pathological section pixels are smaller than the preset pixels, creating a blank picture, wherein the pixels of the blank picture are equal to the preset pixels, and the analysis processing module patches the pathological section which is smaller than the preset pixels on the blank picture, and the storage module stores the patched blank picture;
a3: if the cut pathological section pixels are equal to the preset pixels, the storage module directly stores the pictures of the cut pathological section;
a4: the analysis processing module analyzes and splices the patched blank picture and the cut pathological section which is equal to the preset pixel, scans the analyzed and spliced pathological section, generates a pathological section integral picture and stores the pathological section integral picture in the storage module.
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