CN116491903A - Nerve damage area determination method, system, equipment and medium - Google Patents

Nerve damage area determination method, system, equipment and medium Download PDF

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CN116491903A
CN116491903A CN202310477135.6A CN202310477135A CN116491903A CN 116491903 A CN116491903 A CN 116491903A CN 202310477135 A CN202310477135 A CN 202310477135A CN 116491903 A CN116491903 A CN 116491903A
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ultrasonic
myoelectric
determining
nerve damage
nerves
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涂宗祺
周宇峰
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Chongqing Medical University
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Chongqing Medical University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/388Nerve conduction study, e.g. detecting action potential of peripheral nerves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • A61B5/397Analysis of electromyograms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy

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Abstract

The invention provides a nerve damage area determining method, a system, equipment and a medium.

Description

Nerve damage area determination method, system, equipment and medium
Technical Field
The application relates to the technical field of medicine, in particular to a method, a system, equipment and a medium for determining a nerve damage area.
Background
Focused ultrasound ablation surgery (focused ultrasound ablation surgery, FUAS) is a non-invasive treatment technique, has the advantages of non-invasiveness, targeting, penetrability of human tissues, controllable energy distribution and the like, and is currently applied to the treatment of various gynaecological and obstetrical diseases, such as hysteromyoma, adenomyosis, scar pregnancy, placenta implantation and the like. The focused ultrasound ablation operation is safe and effective, is easy to accept by patients, and has wide application prospect.
Nonetheless, complications of focused ultrasound ablation procedures also occur during treatment, common complications include: skin, intestinal and nerve damage. In the nerve injury confirmation process, the accumulation of clinician experience and the development of focused ultrasound ablation procedures have reduced the incidence of nerve injury adverse reactions. At present, in clinical practice, injury information is mostly obtained through subjective feedback (such as pain and leg numbness) of a patient, and a doctor timely adjusts ultrasonic parameters according to the injury information fed back by the patient, so that the risk of nerve injury is reduced. However, the sensitivity of the patient to the pain is quite different, and accurate and reliable damage early warning information cannot be provided; if the occurrence of nerve damage is avoided or reduced by simply relying on the experience of a doctor, the learning curve using this technique becomes long, and the safety of treatment cannot be fully ensured.
Disclosure of Invention
In view of the above-mentioned drawbacks of the prior art, the present invention provides a method, a system, a device and a medium for determining a nerve damage area, so as to solve the problem that in the process of determining the nerve damage area, the sensitivity of a patient to pain is greatly different, and accurate and reliable damage early-warning information cannot be provided; if the occurrence of nerve damage is avoided or reduced by simply relying on the experience of a doctor, the learning curve using this technique becomes long, and the technical problem of safety of treatment cannot be completely ensured.
In an exemplary embodiment of the present application, the present invention provides a method of determining a nerve damage region, the determining of the nerve damage region including:
acquiring myoelectric physiological indexes of the skin surfaces of nerves of a plurality of different positions, wherein the myoelectric physiological indexes are obtained by irradiating the skin surfaces of the nerves which are coincident with the focused ultrasonic focus of the B-ultrasonic system through the B-ultrasonic system, the B-ultrasonic system comprises a B-ultrasonic probe, a focused ultrasonic transducer and a coupling cone, the first end of the focused ultrasonic transducer is provided with a mounting hole for mounting the probe, the B-ultrasonic probe is mounted on the mounting hole, and the coupling cone is fixedly arranged at the second end of the focused ultrasonic transducer;
determining the states of nerves of different parts based on the myoelectric physiological indexes and a preset myoelectric physiological index interval range, wherein the states comprise normal and damaged states, and the preset myoelectric physiological index interval range is obtained by irradiating the skin surface of a plurality of normal nerves which are coincident with the focused ultrasonic focus of the B ultrasonic-focused ultrasonic system through the B ultrasonic-focused ultrasonic system;
the nerve damage region is determined based on the status of the nerves at several different locations.
In an exemplary embodiment of the present application, the pulse width is 0.8-2ms during the irradiation.
In an exemplary embodiment of the present application, the pulse repetition frequency during the irradiation is 1-100Hz.
In an exemplary embodiment of the present application, the sound intensity is < 4W/cm during the irradiation 2
In an exemplary embodiment of the present application, determining the status of the respective nerve includes:
if the myoelectric physiological index is within the range of the preset myoelectric physiological index interval, the state of the corresponding nerve is determined to be normal.
In another exemplary embodiment of the present application, determining the status of the respective nerve further comprises:
if the myoelectric physiological index exceeds the range of the preset myoelectric physiological index interval, determining the state of the corresponding nerve as damaged.
In an exemplary embodiment of the present application, determining a nerve damage region includes:
if the states of the nerves of adjacent parts are damaged and normal respectively, the area between the adjacent parts is determined as a nerve damaged area.
In an exemplary embodiment of the present application, the present invention further provides a nerve damage area determining system, the nerve damage area determining method system including:
the system comprises an acquisition module, a B-ultrasonic-focusing ultrasonic system and a coupling cone, wherein the acquisition module is configured to acquire myoelectric physiological indexes of the skin surfaces of nerves of a plurality of different parts, the myoelectric physiological indexes are obtained by irradiating the skin surfaces of the nerves which are coincident with the focusing ultrasonic focus of the B-ultrasonic-focusing ultrasonic system through the B-ultrasonic-focusing ultrasonic system, the B-ultrasonic-focusing ultrasonic system comprises a B-ultrasonic probe, a focusing ultrasonic transducer and the coupling cone, the first end of the focusing ultrasonic transducer is provided with a mounting hole for mounting the probe, the B-ultrasonic probe is mounted on the mounting hole, and the coupling cone is fixedly arranged at the second end of the focusing ultrasonic transducer;
the state determining module is configured to determine states of nerves of different parts based on the myoelectric physiological indexes and a preset myoelectric physiological index interval range, wherein the states comprise normal and damaged, and the preset myoelectric physiological index interval range is obtained by irradiating the skin surface of a plurality of normal nerves which are coincident with the focused ultrasonic focuses of the B ultrasonic-focusing ultrasonic system through the B ultrasonic-focusing ultrasonic system;
a nerve damage region determination module configured to determine a nerve damage region based on states of nerves of a number of different locations.
In an exemplary embodiment of the present application, the present invention further provides an electronic device, including:
one or more processors;
and a storage means for storing one or more programs that, when executed by the one or more processors, cause the electronic device to implement the nerve damage area determination method as described above.
In an exemplary embodiment of the present application, the present invention also provides a computer-readable storage medium having stored thereon a computer program which, when executed by a processor of a computer, causes the computer to perform the nerve damage area determining method as described above.
The invention has the beneficial effects that:
according to the method, the myoelectric physiological indexes of the skin surfaces of the nerves of a plurality of different positions are obtained, the states of the nerves of the different positions are determined based on the myoelectric physiological indexes and the preset region range of the myoelectric physiological indexes, the states comprise normal states and damaged states, the damaged areas of the nerves are determined based on the states of the nerves of the plurality of different positions, and then pain of patients in the detection process is reduced.
In this application, irradiation parameter is controllable, sets up in a flexible way, is applicable to the nerve damage of different degree, has avoided relying on clinician experience to detect in the prior art and probably causes the technical problem of further harm to impaired nerve, for example, the nerve damage that different diseases caused is different to focusing ultrasonic tolerance, like compare in normal nerve tissue, diabetes cause peripheral neuropathy in can bear more doses supersound, but once impaired then be difficult to resume.
In the application, the FUS dose is low in the focused ultrasonic radiation process, and the use is safe. Also, the use of FUS of low intensity can promote recovery of damaged nerves.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the application.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the application and together with the description, serve to explain the principles of the application. It is apparent that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained from these drawings without inventive effort for a person of ordinary skill in the art. In the drawings:
FIG. 1 is a flow chart illustrating a method of determining a nerve damage area according to an exemplary embodiment of the present application;
FIG. 2 is a flow chart of an exemplary embodiment of determining the status of the corresponding nerve in the embodiment of FIG. 1;
FIG. 3 is a flow chart of another exemplary embodiment of determining the status of the corresponding nerve in the embodiment of FIG. 1;
FIG. 4 is a flow chart of an exemplary embodiment of determining a nerve damage area in the embodiment of FIG. 1;
FIG. 5 is a flow chart illustrating a method of determining a nerve damage area according to an embodiment of the present application;
FIG. 6 is a schematic diagram of a B-ultrasonic-focusing ultrasonic system according to the embodiment shown in FIG. 5;
FIG. 7 is a schematic diagram of the configuration of a coupling cone in the B-ultrasonic-focusing ultrasonic system of FIG. 6;
FIG. 8 is an assembly view of a coupling cone and a focused ultrasound transducer in the B-ultrasound-focused ultrasound system of FIG. 6;
FIG. 9 is a schematic illustration of the irradiation of nerves in the embodiment shown in FIG. 5;
FIG. 10 is a block diagram of a nerve damage area determination system shown in an exemplary embodiment of the present application;
fig. 11 shows a schematic diagram of a computer system suitable for use in implementing the electronic device of the embodiments of the present application.
Detailed Description
Further advantages and effects of the present invention will become readily apparent to those skilled in the art from the disclosure herein, by referring to the accompanying drawings and the preferred embodiments. The invention may be practiced or carried out in other embodiments that depart from the specific details, and the details of the present description may be modified or varied from the spirit and scope of the present invention. It should be understood that the preferred embodiments are presented by way of illustration only and not by way of limitation.
It should be noted that the illustrations provided in the following embodiments merely illustrate the basic concept of the present invention by way of illustration, and only the components related to the present invention are shown in the drawings and are not drawn according to the number, shape and size of the components in actual implementation, and the form, number and proportion of the components in actual implementation may be arbitrarily changed, and the layout of the components may be more complicated.
In the following description, numerous details are set forth in order to provide a more thorough explanation of embodiments of the present invention, it will be apparent, however, to one skilled in the art that embodiments of the present invention may be practiced without these specific details, in other embodiments, well-known structures and devices are shown in block diagram form, rather than in detail, in order to avoid obscuring the embodiments of the present invention.
Referring to fig. 1, fig. 1 is a flowchart of a method for determining a nerve damage area according to an exemplary embodiment of the present application, where the method is used for solving the problem that in a process of determining a nerve damage area by adopting an existing method, sensitivity of a patient to pain is greatly different, and accurate and reliable damage early-warning information cannot be provided; if the occurrence of nerve damage is avoided or reduced by simply relying on the experience of a doctor, the learning curve using this technique becomes long, and the technical problem of safety of treatment cannot be completely ensured.
As shown in fig. 1, in an exemplary embodiment of the present application, the method for determining a nerve damage area includes at least steps S110 to S130, which are described in detail as follows:
s110, acquiring myoelectric physiological indexes of the skin surface of nerves at different positions;
in the application, the myoelectric physiological index is obtained by irradiating the skin surface of the corresponding nerve overlapped with the focused ultrasonic focus of the B ultrasonic-focused ultrasonic system through the B ultrasonic-focused ultrasonic system, the B ultrasonic-focused ultrasonic system comprises a B ultrasonic probe, a focused ultrasonic transducer and a coupling cone, the first end of the focused ultrasonic transducer is provided with a mounting hole for mounting the probe, the B ultrasonic probe is mounted on the mounting hole, the first end of the coupling cone (the coupling cone is provided with a cavity) is fixedly arranged at the second end of the focused ultrasonic transducer, during irradiation, the second end of the coupling cone is provided with a water inlet for supplying deaerated water into the cavity inside the coupling cone, and during irradiation, the B ultrasonic probe faces the corresponding nerve;
in the irradiation process, the pulse width is 0.8-2ms, the pulse repetition frequency is 1-100Hz, and the sound intensity is less than 4W/cm 2
Myoelectric physiological indexes comprise conduction speed, latency period, action potential and the like;
s120, determining the state of a corresponding nerve based on the myoelectric physiological index and a preset myoelectric physiological index interval range;
it is to be noted that the state includes normal and damaged, and the range of the preset myoelectric physiological index interval is obtained by irradiating a plurality of normal nerves which are coincident with the focused ultrasonic focuses of the B ultrasonic-focusing ultrasonic system by the B ultrasonic-focusing ultrasonic system;
step S130, determining a nerve damage area based on the states of the nerves of a plurality of different parts.
In the related art, the occurrence of adverse effects of nerve injury has been reduced by accumulation of clinician experience and development of focused ultrasound ablation procedures during nerve injury confirmation. At present, in clinical practice, injury information is mostly obtained through subjective feedback (such as pain and leg numbness) of a patient, and a doctor timely adjusts ultrasonic parameters according to the injury information fed back by the patient, so that the risk of nerve injury is reduced. The inventor generates power after analyzing the related technology, the sensitivity of patients to pains is larger, and accurate and reliable damage early warning information cannot be provided; if the occurrence of nerve damage is avoided or reduced by simply relying on the experience of a doctor, the learning curve using this technique becomes long, and the safety of treatment cannot be fully ensured. Therefore, the inventor considers that by acquiring the myoelectric physiological indexes of the skin surfaces of the nerves of a plurality of different parts, the states of the corresponding nerves are determined based on the myoelectric physiological indexes and the preset myoelectric physiological index interval range, the states comprise normal and damaged states, and the damaged areas of the nerves are determined based on the states of the nerves of a plurality of different parts, so that the pain of patients in the detection process is reduced, and the technical problem that the damaged nerves are possibly damaged further by the detection by the experience of clinicians in the prior art is avoided.
Referring to fig. 2, fig. 2 is a flow chart of determining the status of the corresponding nerve in the embodiment shown in fig. 1 in an exemplary embodiment.
As shown in fig. 2, in an exemplary embodiment of the present application, the process of determining the status of the corresponding nerve in the embodiment shown in fig. 1 includes step S210, which is described in detail below:
and S210, if the myoelectric physiological index is within the range of the preset myoelectric physiological index interval, determining the state of the corresponding nerve as normal.
Fig. 3 is a flow chart of another exemplary embodiment of determining the status of the corresponding nerve in the embodiment shown in fig. 1.
As shown in fig. 3, in another exemplary embodiment of the present application, the process of determining the status of the corresponding nerve in the embodiment shown in fig. 1 further includes step S320, which is described in detail below:
and S320, if the myoelectric physiological index exceeds the range of the preset myoelectric physiological index interval, determining the state of the corresponding nerve as damaged.
Specifically, if the myoelectric physiological index is not within the preset myoelectric physiological index interval, the state of the corresponding nerve is determined to be damaged.
Referring to fig. 4, fig. 4 is a flow chart of determining a nerve damage area in an exemplary embodiment in the embodiment shown in fig. 1.
As shown in fig. 4, in an exemplary embodiment of the present application, the process of determining a nerve damage area in the embodiment shown in fig. 1 includes step S410, which is described in detail below:
step S410, if the states of the nerves of adjacent parts are damaged and normal respectively, determining the areas between the adjacent parts as nerve damaged areas.
Referring to fig. 5, fig. 5 is a flowchart illustrating a method for determining a nerve damage region according to an embodiment of the present application, where the method for determining a nerve damage region relies on a B-ultrasonic-focused system. As shown in fig. 6, the B-ultrasonic-focusing ultrasonic system comprises a B-ultrasonic probe, a focusing ultrasonic transducer (i.e. FUS transducer) and a coupling cone, wherein a mounting hole for mounting the probe is arranged at a first end of the focusing ultrasonic transducer, the B-ultrasonic probe is mounted on the mounting hole, a first end of the coupling cone (the coupling cone is provided with a cavity) is fixedly arranged at a second end of the focusing ultrasonic transducer, and in the irradiation process, a water inlet for feeding deaerated water into the cavity inside the coupling cone is arranged at the second end of the coupling cone (as shown in fig. 7), wherein the assembly diagram of the coupling cone and the focusing ultrasonic transducer is shown in fig. 8. The B ultrasonic probe, the focusing ultrasonic transducer and the coupling cone are all in the prior art, and are not described in detail herein.
As shown in fig. 5, in a specific embodiment of the present application, the nerve damage area determining method includes the following steps:
determining which side of the leg has sciatic nerve injury;
coating an ultrasonic couplant on the skin surface of the thigh at the proximal end;
placing a pre-filled degassed water B-ultrasound focused system on the surface of the skin coated with the couplant;
adjusting the B-ultrasonic-focusing ultrasonic system up and down according to the ultrasonic image prompt so that the FUS focus (namely, the focused ultrasonic focus) coincides with the target nerve (namely, the corresponding nerve) (as shown in figure 9);
placing myoelectric recording electrodes in respective muscle blocks or sequentially in a plurality of muscle blocks;
directing the B ultrasonic probe to the corresponding nerve, wherein the pulse width is 0.8-2ms, the pulse repetition frequency is 1-100Hz, and the sound intensity is less than 4W/cm 2 Irradiating a plurality of different nerves under the condition of specific parameters to obtain myoelectric physiological indexes (namely electric physiological indexes) of the skin surfaces of the nerves at a plurality of different positions, wherein the myoelectric physiological indexes comprise conduction speed, latency period, action potential and the like;
determining the state of the corresponding nerve based on the myoelectric physiological index and the preset myoelectric physiological index interval range, wherein the state comprises normal and damaged, specifically, if the myoelectric physiological index is in the preset myoelectric physiological index interval range, determining the state of the corresponding nerve as normal, specifically, determining the state of the corresponding nerve as normal if the conduction speed, the latency period and the action potential are all in the corresponding preset myoelectric physiological index interval range; if the myoelectric physiological index exceeds the preset myoelectric physiological index interval range, namely if the myoelectric physiological index is not in the preset myoelectric physiological index interval range, determining the state of the corresponding nerve as damaged, specifically, determining the state of the corresponding nerve as damaged if any one index of the conduction speed, the latency period and the action potential is not in the corresponding preset myoelectric physiological index interval range;
the skin surface irradiation method comprises the steps that a preset myoelectric physiological index interval range is obtained by irradiating the skin surface of a plurality of normal nerves which are coincident with the focused ultrasonic focuses of the B ultrasonic-focused ultrasonic system through the B ultrasonic-focused ultrasonic system under the condition of the same irradiation parameters of the corresponding nerves;
the nerve damage region is determined based on the states of the nerves of several different sites, specifically, if the states of the nerves of adjacent sites are damaged and normal, respectively, the region between the adjacent sites is determined as the nerve damage region.
Referring to fig. 10, fig. 10 is a block diagram of a nerve damage area determination system according to an exemplary embodiment of the present application.
As shown in fig. 10, in an exemplary embodiment of the present application, the nerve damage area determination system M1000 includes:
an acquisition module M1010 configured to acquire myoelectric physiological indicators of the skin surface of nerves of a number of different sites;
in the application, the myoelectric physiological index is obtained by irradiating a corresponding nerve which coincides with a focused ultrasonic focus of the B ultrasonic-focused ultrasonic system by the B ultrasonic-focused ultrasonic system, the B ultrasonic-focused ultrasonic system comprises a B ultrasonic probe, a focused ultrasonic transducer and a coupling cone, a first end of the focused ultrasonic transducer is provided with a mounting hole for mounting the probe, a second end of the focused ultrasonic transducer is provided with a concave surface, the B ultrasonic probe is mounted on the mounting hole, a first end of the coupling cone (the coupling cone is provided with a cavity) is fixedly arranged at the second end of the focused ultrasonic transducer, and in the irradiation process, a water inlet for supplying deaerated water into the cavity inside the coupling cone is arranged at the second end of the coupling cone, and the B ultrasonic probe faces the corresponding nerve during irradiation; in the irradiation process, the pulse width is 0.8-2ms, the pulse repetition frequency is 1-100Hz, and the sound intensity is less than 4W/cm 2
A state determining module M1020 configured to determine a state of the corresponding nerve based on the myoelectric physiological index and a preset myoelectric physiological index interval range;
it is to be noted that the state includes normal and damaged, and the range of the preset myoelectric physiological index interval is obtained by irradiating a plurality of normal nerves which are coincident with the focused ultrasonic focuses of the B ultrasonic-focusing ultrasonic system by the B ultrasonic-focusing ultrasonic system;
the nerve damage area determination module M1030 is configured to determine a nerve damage area based on the states of the nerves of the several different sites.
It should be noted that, the nerve damage area determining system provided in the above embodiment and the nerve damage area determining method provided in the above embodiment belong to the same concept, and the specific manner in which each module and unit perform the operation has been described in detail in the method embodiment, which is not repeated here. In practical application, the nerve damage area determining system provided in the above embodiment may allocate the functions to different functional modules according to needs, that is, the internal structure of the device is divided into different functional modules to perform all or part of the functions described above, which is not limited herein.
The embodiment of the application also provides electronic equipment, which comprises: one or more processors; and a storage means for storing one or more programs that, when executed by the one or more processors, cause the electronic device to implement the nerve damage area determination method provided in the respective embodiments described above.
Fig. 11 shows a schematic diagram of a computer system suitable for use in implementing the electronic device of the embodiments of the present application. It should be noted that, the computer system 1100 of the electronic device shown in fig. 11 is only an example, and should not impose any limitation on the functions and the application scope of the embodiments of the present application.
As shown in fig. 11, the computer system 1100 includes a central processing unit (Central Processing Unit, CPU) 1101 that can perform various appropriate actions and processes, such as performing the method described in the above embodiment, according to a program stored in a Read-Only Memory (ROM) 1102 or a program loaded from a storage section 1108 into a random access Memory (Random Access Memory, RAM) 1103. In the RAM 1103, various programs and data required for system operation are also stored. The CPU 1101, ROM 1102, and RAM 1103 are connected to each other by a bus 1104. An Input/Output (I/O) interface 1105 is also connected to bus 1104.
The following components are connected to the I/O interface 1105: an input section 1106 including a keyboard, a mouse, and the like; an output portion 1107 including a Cathode Ray Tube (CRT), a liquid crystal display (Liquid Crystal Display, LCD), and a speaker; a storage section 1108 including a hard disk or the like; and a communication section 1109 including a network interface card such as a LAN (Local Area Network ) card, a modem, or the like. The communication section 1109 performs communication processing via a network such as the internet. The drive 1110 is also connected to the I/O interface 1105 as needed. Removable media 1111, such as a magnetic disk, an optical disk, a magneto-optical disk, a semiconductor memory, or the like, is installed as needed on drive 1110, so that a computer program read therefrom is installed as needed into storage section 1108.
In particular, according to embodiments of the present application, the processes described above with reference to flowcharts may be implemented as computer software programs. For example, embodiments of the present application include a computer program product comprising a computer program embodied on a computer readable medium, the computer program comprising a computer program for performing the method shown in the flowchart. In such an embodiment, the computer program can be downloaded and installed from a network via the communication portion 1109, and/or installed from the removable media 1111. When executed by a Central Processing Unit (CPU) 1101, performs the various functions defined in the system of the present application.
It should be noted that, the computer readable medium shown in the embodiments of the present application may be a computer readable signal medium or a computer readable storage medium, or any combination of the two. The computer readable storage medium may be, for example, an electronic, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, or device, or any combination thereof. More specific examples of the computer-readable storage medium may include, but are not limited to: an electrical connection having one or more wires, a portable computer diskette, a hard disk, a Random Access Memory (RAM), a read-Only Memory (ROM), an erasable programmable read-Only Memory (Erasable Programmable Read Only Memory, EPROM), flash Memory, an optical fiber, a portable compact disc read-Only Memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing. In the present application, a computer-readable signal medium may include a data signal propagated in baseband or as part of a carrier wave, with a computer-readable computer program embodied therein. Such a propagated data signal may take any of a variety of forms, including, but not limited to, electro-magnetic, optical, or any suitable combination of the foregoing. A computer readable signal medium may also be any computer readable medium that is not a computer readable storage medium and that can communicate, propagate, or transport a program for use by or in connection with an instruction execution system, apparatus, or device. A computer program embodied on a computer readable medium may be transmitted using any appropriate medium, including but not limited to: wireless, wired, etc., or any suitable combination of the foregoing.
The flowcharts and block diagrams in the figures illustrate the architecture, functionality, and operation of possible implementations of systems, methods and computer program products according to various embodiments of the present application. Where each block in the flowchart or block diagrams may represent a module, segment, or portion of code, which comprises one or more executable instructions for implementing the specified logical function(s). It should also be noted that, in some alternative implementations, the functions noted in the block may occur out of the order noted in the figures. For example, two blocks shown in succession may, in fact, be executed substantially concurrently, or the blocks may sometimes be executed in the reverse order, depending upon the functionality involved. It will also be noted that each block of the block diagrams or flowchart illustration, and combinations of blocks in the block diagrams or flowchart illustration, can be implemented by special purpose hardware-based systems which perform the specified functions or acts, or combinations of special purpose hardware and computer instructions.
The units involved in the embodiments of the present application may be implemented by means of software, or may be implemented by means of hardware, and the described units may also be provided in a processor. Wherein the names of the units do not constitute a limitation of the units themselves in some cases.
Another aspect of the present application also provides a computer-readable storage medium having stored thereon a computer program which, when executed by a processor of a computer, causes the computer to perform the method of determining a nerve damage area as described above. The computer-readable storage medium may be included in the electronic device described in the above embodiment or may exist alone without being incorporated in the electronic device.
Another aspect of the present application also provides a computer program product or computer program comprising computer instructions stored in a computer readable storage medium. The processor of the computer device reads the computer instructions from the computer-readable storage medium, and the processor executes the computer instructions, so that the computer device performs the nerve damage area determination method provided in the above-described respective embodiments.
The above embodiments are merely illustrative of the principles of the present invention and its effectiveness, and are not intended to limit the invention. Modifications and variations may be made to the above-described embodiments by those skilled in the art without departing from the spirit and scope of the invention. It is therefore intended that all equivalent modifications and changes made by those skilled in the art without departing from the spirit and technical spirit of the present invention shall be covered by the appended claims.

Claims (10)

1. A method of determining a nerve damage region, the determining the nerve damage region comprising:
acquiring myoelectric physiological indexes of the skin surfaces of nerves of a plurality of different positions, wherein the myoelectric physiological indexes are obtained by irradiating the skin surfaces of the nerves which are coincident with the focused ultrasonic focus of the B-ultrasonic system through the B-ultrasonic system, the B-ultrasonic system comprises a B-ultrasonic probe, a focused ultrasonic transducer and a coupling cone, the first end of the focused ultrasonic transducer is provided with a mounting hole for mounting the probe, the B-ultrasonic probe is mounted on the mounting hole, and the coupling cone is fixedly arranged at the second end of the focused ultrasonic transducer;
determining the states of nerves of different parts based on the myoelectric physiological indexes and a preset myoelectric physiological index interval range, wherein the states comprise normal and damaged states, and the preset myoelectric physiological index interval range is obtained by irradiating the skin surface of a plurality of normal nerves which are coincident with the focused ultrasonic focus of the B ultrasonic-focused ultrasonic system through the B ultrasonic-focused ultrasonic system;
the nerve damage region is determined based on the status of the nerves at several different locations.
2. The method of claim 1, wherein the pulse width during the irradiating is 0.8-2ms.
3. The method of claim 1, wherein the pulse repetition frequency during the irradiating is 1-100Hz.
4. The method for determining a nerve damage area according to claim 1, wherein the sound intensity is < 4W/cm during the irradiation 2
5. The method of determining a nerve damage area of claim 1, wherein determining the status of the respective nerve comprises:
if the myoelectric physiological index is within the range of the preset myoelectric physiological index interval, the state of the corresponding nerve is determined to be normal.
6. The method of determining a nerve damage area of claim 5, wherein determining the status of the respective nerve further comprises:
if the myoelectric physiological index exceeds the range of the preset myoelectric physiological index interval, determining the state of the corresponding nerve as damaged.
7. The method of determining a nerve damage area according to claim 1, wherein determining a nerve damage area comprises:
if the states of the nerves of adjacent parts are damaged and normal respectively, the area between the adjacent parts is determined as a nerve damaged area.
8. A nerve damage area determination system, wherein the nerve damage area determination method system comprises:
the system comprises an acquisition module, a B-ultrasonic-focusing ultrasonic system and a coupling cone, wherein the acquisition module is configured to acquire myoelectric physiological indexes of the skin surfaces of nerves of a plurality of different parts, the myoelectric physiological indexes are obtained by irradiating the skin surfaces of the nerves which are coincident with the focusing ultrasonic focus of the B-ultrasonic-focusing ultrasonic system through the B-ultrasonic-focusing ultrasonic system, the B-ultrasonic-focusing ultrasonic system comprises a B-ultrasonic probe, a focusing ultrasonic transducer and the coupling cone, the first end of the focusing ultrasonic transducer is provided with a mounting hole for mounting the probe, the B-ultrasonic probe is mounted on the mounting hole, and the coupling cone is fixedly arranged at the second end of the focusing ultrasonic transducer;
the state determining module is configured to determine states of nerves of different parts based on the myoelectric physiological indexes and a preset myoelectric physiological index interval range, wherein the states comprise normal and damaged, and the preset myoelectric physiological index interval range is obtained by irradiating the skin surface of a plurality of normal nerves which are coincident with the focused ultrasonic focuses of the B ultrasonic-focusing ultrasonic system through the B ultrasonic-focusing ultrasonic system;
a nerve damage region determination module configured to determine a nerve damage region based on states of nerves of a number of different locations.
9. An electronic device, the electronic device comprising:
one or more processors;
storage means for storing one or more programs that, when executed by the one or more processors, cause the electronic device to implement the nerve damage area determination method of any one of claims 1-7.
10. A computer-readable storage medium, having stored thereon a computer program which, when executed by a processor of a computer, causes the computer to perform the nerve damage area determination method according to any one of claims 1-7.
CN202310477135.6A 2023-04-27 2023-04-27 Nerve damage area determination method, system, equipment and medium Pending CN116491903A (en)

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