CN116461997A - Sample processing device - Google Patents

Sample processing device Download PDF

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Publication number
CN116461997A
CN116461997A CN202310463612.3A CN202310463612A CN116461997A CN 116461997 A CN116461997 A CN 116461997A CN 202310463612 A CN202310463612 A CN 202310463612A CN 116461997 A CN116461997 A CN 116461997A
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CN
China
Prior art keywords
sample
consumable
sample processing
module
processing device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202310463612.3A
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Chinese (zh)
Inventor
潘国龙
田雪佳
刘瑞琪
张文凭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rongzhi Biotechnology Qingdao Co ltd
Original Assignee
Rongzhi Biotechnology Qingdao Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rongzhi Biotechnology Qingdao Co ltd filed Critical Rongzhi Biotechnology Qingdao Co ltd
Priority to CN202310463612.3A priority Critical patent/CN116461997A/en
Publication of CN116461997A publication Critical patent/CN116461997A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G61/00Use of pick-up or transfer devices or of manipulators for stacking or de-stacking articles not otherwise provided for
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G57/00Stacking of articles
    • B65G57/02Stacking of articles by adding to the top of the stack
    • B65G57/16Stacking of articles of particular shape
    • B65G57/20Stacking of articles of particular shape three-dimensional, e.g. cubiform, cylindrical

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The present invention relates to a sample processing device. The sample processing device includes: a base frame; a sample processing module disposed on the pedestal; consumable management component, consumable management component includes perception module, piles up the module and transport the module, perception module is arranged every sample processing module is with detecting and is located sample consumable in the sample processing module is used up, pile up the module and arrange on the bed frame and include many spare sample consumable, transport the module movably fix on the bed frame, and when perception module detects corresponding sample processing module in sample consumable is used up, transport the module and be configured to snatch one spare sample consumable and shift it to sample processing module is last in order to replace the sample consumable that uses up. The sample processing device can automatically manage sample consumable materials in the sample processing process.

Description

Sample processing device
Technical Field
The invention relates to the field of biological sample detection, in particular to a sample processing device.
Background
The sample processing device is a device for automatically processing biological samples, and is widely applied to the field of biological sample detection, such as nucleic acid extraction, IGF-1 detection, GHB detection, NGS library preparation and the like. For different detection types, different sample processing components are usually provided on the sample processing device. For example, a sample processing device generally includes sample processing means such as a pipetting device, a magnetometric rack device, an oscillation device, a heating and drying device, and a reagent tank. The sample processing components are matched with each other according to a preset experimental flow, and the biological sample is subjected to extraction, purification and other treatments so as to facilitate subsequent detection and analysis.
When a sample processing device is used for processing biological samples, consumable materials are usually required to be replaced timely so as to ensure the cleanliness of sample processing. Still taking nucleic acid extraction as an example, consumables include a gun head of a pipetting device, a deep well plate for holding reagents in a reagent tank, and the like. After the consumable is used, the user needs to judge the type of the consumable by himself, then take the consumable from the material preparation area, and then replace the consumable. The manual operation mode is inconvenient to operate, low in efficiency and easy to pollute consumable materials so as to influence the result of sample detection.
Accordingly, there is a need in the art for a new solution to the above-mentioned problems.
Disclosure of Invention
The invention provides a sample processing device, which aims to solve the technical problem that the sample processing device in the prior art cannot realize automatic management of sample consumable materials. The sample processing device includes: a base frame; a sample processing module disposed on the pedestal; consumable management component, consumable management component includes perception module, piles up the module and transport the module, perception module is arranged every sample processing module is with detecting and is located sample consumable in the sample processing module is used up, pile up the module and arrange on the bed frame and include many spare sample consumable, transport the module movably fix on the bed frame, and when perception module detects corresponding sample processing module in sample consumable is used up, transport the module and be configured to snatch one spare sample consumable and shift it to sample processing module is last in order to replace the sample consumable that uses up.
The sample processing device comprises a pedestal, a sample processing module and a consumable management assembly. The sample processing module is arranged on the pedestal to process the sample differently depending on the type of sample detection. The consumable management component comprises a sensing module, a stacking module and a transferring module. Wherein a sensing module is arranged on each sample processing module to detect whether a sample consumable located in the sample processing module is spent. The stacking module is disposed on the pedestal and includes a plurality of spare sample consumables. The transport module is movably secured to the pedestal and when the sensing module detects that a sample consumable in a corresponding sample processing module is spent, the transport module is configured to grasp and transfer a spare sample consumable to the sample processing module to replace the spent sample consumable. Through the cooperation of perception module, pile up module and transport module, can in time transfer reserve sample consumable to sample processing module after the sample consumable in the sample processing module is used up, realize the automated management of sample consumable, improve sample processing device's degree of automation. In addition, sample processing module and consumable management module all arrange on the bed frame, can also shorten the transportation stroke of sample consumable, improve the efficiency of transporting and changing.
In a preferred embodiment of the above sample processing device, the sample processing module includes a mounting plate and a sample processing member detachably arranged on the mounting plate, and the sensing module is fixed to the mounting plate. The sample processing component is detachably arranged on the mounting plate, so that the sample processing component can be conveniently disassembled and assembled, and the matched sample processing component can be flexibly selected according to the requirements of different detection types so as to meet the requirements of different detection types. In addition, the sensing module is fixed on the mounting plate, so that whether the sample consumable in the sample processing module is used up or not can be conveniently detected, and the sample consumable can be replaced in time.
In a preferred embodiment of the above sample processing device, the mounting plate is provided with a plurality of elastic pieces and a plurality of fixing columns, and the plurality of elastic pieces and the plurality of fixing columns are spaced apart from each other along a circumferential direction of the mounting plate and together enclose a mounting area that can restrain the sample processing member. The cooperation of shell fragment and fixed column can be convenient for the sample processing part install and the location on the mounting panel.
In a preferred embodiment of the above sample processing device, the transfer module includes: the three-dimensional platform is fixed on the base frame; and a manipulator movably fixed on the three-dimensional platform and configured to grasp the sample consumable and the standby sample consumable. Through foretell setting, can conveniently realize snatching and transporting of sample consumptive material and reserve sample consumptive material.
In the above preferred technical solution of the sample processing device, the manipulator is further provided with a code scanner for scanning an information code of the standby sample consumable, so as to obtain a type of the standby sample consumable. The code scanner is arranged, so that the information of the standby sample consumable can be conveniently identified, and the appropriate standby sample consumable can be accurately grasped.
In a preferred embodiment of the above sample processing device, the manipulator includes a mechanical clamping jaw for clamping the standby sample consumable, and a code scanner fixing plate for fixing the code scanner is provided on the mechanical clamping jaw. The setting of mechanical clamping jaw can be convenient for snatch sample consumable and reserve sample consumable. The code scanner is arranged on the scanner fixing plate fixedly arranged on the mechanical clamping jaw, so that the code scanner can conveniently and accurately scan the information code of the standby sample consumable.
In a preferred embodiment of the above sample processing device, the stacking module includes: a fixed base disposed on the base frame; and a limiting plate configured to extend vertically upward along a circumferential edge of the stationary base so as to define, with the stationary base, a chamber containing the standby sample consumable. Through foretell setting for reserve sample consumptive material can be stable and regularly pile up on unable adjustment base, and the module of being convenient for is snatched it.
In a preferred embodiment of the above sample processing device, the limiting plate includes a left limiting plate and a right limiting plate disposed opposite to each other on both sides of the fixing base, and each of the left limiting plate and the right limiting plate is a U-shaped member with an upward opening. Through foretell setting for the limiting plate has simple structure, is convenient for processing manufacturing.
In the preferred technical scheme of the sample processing device, a detection device is arranged on the limiting plate to detect the height of the standby sample consumable in the cavity. Through the arrangement, the height of the standby sample consumable in the cavity can be conveniently detected, so that the manipulator can accurately position and grasp the standby sample consumable.
In the preferred technical solution of the above sample processing device, the sample consumable and the standby sample consumable respectively include a gun head, a shallow well plate, a PCR plate, and a deep well plate. Through the arrangement, the types of consumable materials can be enriched, and the requirement of the consumable materials in the sample processing process is met.
Drawings
Preferred embodiments of the present invention are described below with reference to the accompanying drawings, in which:
FIG. 1 is a schematic view of a sample processing device according to an embodiment of the present invention;
FIG. 2 is a schematic view of an embodiment of a stacking module in a sample processing device of the present invention;
FIG. 3 is a schematic view of the structure of an embodiment of the mounting plate of the sample processing module in the sample processing device of the present invention.
List of reference numerals:
1. a sample processing device; 10. a base frame; 11. a bottom plate; 12. a supporting vertical plate; 121. a left support vertical plate; 122. a right support riser; 20. a sample processing module; 21. a mounting plate; 211. a spring plate; 212. fixing the column; 213. a mounting area; 22. a sample processing component; 23. sample consumables; 30. a consumable management component; 31. a perception module; 32. stacking modules; 321. a fixed base; 3211. a fixed bottom plate; 3212. a support column; 3213. a limit fixing plate; 322. a limiting plate; 322a, left limiting plate; 322b, right limiting plate; 3221. a first limit post; 3222. the second limit column; 3223. a connecting plate; 323. a chamber; 324. a detection device; 325. a support base; 326. standby sample consumables; 33. a transfer module; 331. a three-dimensional platform; 3311. an X-direction slide rail; 3312. a Y-direction slide rail; 3313. a Z-direction slide rail; 332. a manipulator; 3321. mechanical clamping jaws; 3322. a code scanner fixing plate; 40. a code scanner.
Detailed Description
Preferred embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the present invention, and are not intended to limit the scope of the present invention.
It should be noted that, in the description of the present invention, terms such as "upper," "lower," "left," "right," "inner," "outer," and the like indicate directions or positional relationships based on the directions or positional relationships shown in the drawings, which are merely for convenience of description, and do not indicate or imply that the apparatus or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
Furthermore, it should be noted that, in the description of the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "configured," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be directly connected, can be indirectly connected through an intermediate medium, and can also be communicated with the inside of two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art according to the specific circumstances.
In order to solve the technical problem that a sample processing device in the prior art cannot realize automatic management of sample consumables, the invention provides a sample processing device 1. The sample processing device 1 includes: a base frame 10; a sample processing module 20, the sample processing module 20 being arranged on the pedestal 10; a consumable management assembly 30, the consumable management assembly 30 comprising a sensing module 31, a stacking module 32 and a transfer module 33, the sensing module 31 being arranged on each sample processing module 20 to detect whether a sample consumable 23 located in the sample processing module 20 is spent, the stacking module 32 being arranged on the base 10 and comprising a plurality of spare sample consumables 326, the transfer module 33 being movably secured to the base 10, and the transfer module 33 being configured to grasp and transfer a spare sample consumable 326 onto the sample processing module 20 to replace a spent sample consumable 23 when the sensing module 31 detects that a sample consumable 23 in a corresponding sample processing module 20 is spent.
FIG. 1 is a schematic view of a sample processing device according to an embodiment of the present invention. As shown in fig. 1, in one or more embodiments, the sample processing device 1 of the present invention includes a pedestal 10, a plurality of sample processing modules 20, and a consumable management assembly 30. A plurality of sample processing modules 20 are arranged on the pedestal 10 to meet sample processing requirements for different detection types, including, but not limited to, nucleic acid extraction, IGF-1 detection, GHb detection, NGS library preparation, etc. The consumable management assembly 30 is also disposed on the pedestal 10 for timely replacement of the sample consumables 23 spent on the sample processing module 20.
As shown in fig. 1, in one or more embodiments, the base frame 10 includes a base plate 11 and a support riser 12 secured to the base plate 11. The base plate 11 may provide a suitable installation space for the sample processing module 20 and the consumable management assembly 30. In one or more embodiments, the base plate 11 is a generally rectangular plate-like structure. Alternatively, the bottom plate 11 may be provided in a square, circular or other suitable shape. The base plate 11 may be machined from a suitable metal material (e.g., stainless steel, cast iron, etc.) to provide good mechanical properties. Based on the orientation shown in fig. 1, the support riser 12 is fixed to the rear side of the base plate 11, and includes a left support riser 121 and a right support riser 122 spaced apart from each other in the left-right direction. The left and right support risers 121 and 122 are each generally perpendicular to the floor 11. The left support riser 121 and the right support riser 122 are secured to the base plate 11 by, but not limited to, bolting, clamping, welding. The left support riser 121 and the right support riser 122 are used to support and mount the transport module 33 of the consumable management assembly 30. Alternatively, the support risers 12 may be provided in other suitable configurations and numbers, so long as the transfer module 33 is stably supported and installed.
As shown in fig. 1, a plurality of sample processing modules 20 are arranged on the base plate 11 at intervals from each other so as to process biological samples. In one or more embodiments, each sample processing module 20 includes a mounting plate 21 and a sample processing component 22 removably secured to the mounting plate 21. The mounting plate 21 is fixed to the base plate 11 of the base frame 10. The fixing means may be, but is not limited to, screwing, welding, etc.
FIG. 2 is a schematic view of the structure of an embodiment of the mounting plate of the sample processing module in the sample processing device of the present invention. As shown in fig. 2, in one or more embodiments, the mounting plate 21 is a generally rectangular flat plate. The mounting plate 21 may be made of a suitable metal material (e.g., stainless steel, aluminum alloy, etc.), a resin material (e.g., PP, PE, etc.), etc., so as to have good mechanical properties. Based on the orientation shown in fig. 2, 2 elastic pieces 211 and 4 fixing posts 212 spaced apart from each other along the circumferential edge thereof are formed on the upper surface of the mounting plate 21. The 2 spring tabs 211 and the 4 fixing posts 212 together enclose a mounting area 213 for restraining the sample processing component 22. Specifically, each of the fixing posts 212 is configured to extend upward substantially perpendicularly from the upper surface of the mounting plate 21. In addition, the fixed column 212 has a generally tapered shape so that the sample processing member 22 can be conveniently inserted into the mounting region 213 and abutted against the fixed column 212. Each of the elastic pieces 211 is directed toward the middle of the mounting plate 21 so that a pushing force can be applied to the sample processing member 22 by the elastic action of the elastic piece 211 itself when the sample processing member 22 is disposed in the mounting region 213, thereby stably and firmly fixing the sample processing member 22 to the mounting plate 21 together with the fixing posts 212. It should be noted that the number and arrangement positions of the elastic pieces 211 and the fixing posts 212 may be adjusted according to actual needs, as long as the sample processing member 22 can be firmly fixed.
With continued reference to fig. 1, the sample processing component 22 is secured to the floor 11 of the base frame 10 by a mounting plate 21. Sample processing component 22 includes, but is not limited to, a magnetometric rack device, a heated drying device, a shaking device, a gun head cartridge, a reagent reservoir, a sample reservoir, a vascular clamping device. In performing different types of tests on biological samples, the appropriate sample processing component 22 may be selected according to actual needs. For example, in performing nucleic acid extraction, the sample processing member 22 may be selected from a cartridge, a reagent tank, a sample tank, a magnetic rack device, a heat drying device, a shaking device, and the like. In performing the Ghb test, the sample processing component 22 can select a cartridge, a shaking device, a heat drying device, a vascular clamping device, and the like. In addition, a suitable sample consumable 23 is placed on the sample processing device 221 of the sample processing component 22. The sample consumable 23 includes a gun head, a shallow well plate, a PCR plate, a deep well plate, or the like. Before processing the sample, the sample consumable 23 needs to be placed in advance on the corresponding sample processing component 22, for example, the gun head is placed in advance on the gun head cartridge. During processing of the sample, the sample consumable 23 may be used up and replaced in time to avoid contaminating the sample and to continue with the biological sample process or to prepare for the next biological sample process.
As shown in fig. 1 and 2, in one or more embodiments, the consumable management assembly 30 includes a perception module 31, a stacking module 32, and a transport module 33. A sensing module 31 is arranged on each sample processing module 20 to detect whether the sample consumable 23 in the corresponding sample processing module 20 is spent. With continued reference to FIG. 2, in one or more embodiments, the sensing module 31 is secured to the upper surface of the mounting plate 21. The sensing module 31 is in communication with a controller (not shown) of the sample processing device 1 for transmitting the detected results to the controller.
With continued reference to fig. 1, in one or more embodiments, 4 stacked modules 32 are disposed spaced apart from one another in the fore-aft direction on the left side of the floor 11 of the base frame 10. Alternatively, the number of stacked modules 32 may be set to other suitable numbers greater or less than 4, such as 3, 5, etc. Alternatively, the stacking module 32 may be arranged at other suitable positions of the base plate 11, such as the right side or the like.
FIG. 3 is a schematic diagram of an embodiment of a stacking module in a sample processing device of the present invention. As shown in fig. 3, in one or more embodiments, each stack module 32 includes a stationary base 321 and a limiting plate 322 to enclose a chamber 323 that houses a standby sample consumable 326. The standby sample consumables 326 are sequentially arranged in layers within the chamber 323. Spare sample consumables 326 include gun tips, shallow well plates, PCR plates, or deep well plates, among others. The fixing base 321 is disposed on the bottom plate 11 of the base frame 10. In one or more embodiments, the fixing base 321 includes a fixing base plate 3211, a supporting column 3212, a limiting fixing plate 3213, and the like. The fixing base plate 3211 has a substantially rectangular plate-like structure. The fixing means between the fixing base plate 3211 and the base plate 11 includes, but is not limited to, screwing, welding, and the like. In one or more embodiments, a vertically inward extending limit slot (not shown) is formed on the upper surface of the securing base 3211 to receive a support pedestal 325 for supporting the standby sample consumable 326. The 4 support columns 3212 are arranged at four corners of the fixed base plate 3211, respectively. Each support post 3212 has a generally cylindrical shape and is generally perpendicular to the fixed floor 3211. The tops of the support columns 3212 on the left and right sides are respectively provided with 1 limit fixing plate 3213 extending approximately in the front-rear direction.
As shown in fig. 3, the limiting plate 322 extends vertically upward along the circumferential edge of the fixing base 321, and the limiting plate 322 defines a chamber 323 accommodating the standby sample consumable 326 together with the fixing base 321. In one or more embodiments, the limiting plate 322 includes a left limiting plate 322a and a right limiting plate 322b disposed opposite to each other on the left and right sides of the fixing base 321. The left limiting plate 322a is fixed to the limiting fixed plate 3213 located at the left side, and the right limiting plate 322b is fixed to the limiting fixed plate 3213 located at the right side. In one or more embodiments, each of the left and right stop plates 322a, 322b is a U-shaped piece (not identified in the figures) with an upward opening. Specifically, each of the left and right stopper plates 322a and 322b includes first and second stopper posts 3221 and 3222 spaced apart from each other in the front-rear direction, and a connection plate 3222 disposed between the first and second stopper posts 3221 and 3222. The connection plate 3222 is located at lower portions of the first and second stopper posts 3221 and 3222 such that the entire left or right stopper plate 322a or 322b has a generally U-shape. First and second stop posts 3221, 3222 have a generally L-shaped cross-section so as to constrain the standby sample consumables 326 stacked in sequence.
With continued reference to fig. 1 and 3, the support base 325 is disposed on the fixing base 321 and inserted into a chamber 323 defined by the fixing base 321 and the limiting plate 322. In one or more embodiments, the support base 325 is inserted into a limit slot on the fixed base plate 3211 to increase the securement of the installation. Based on the orientation shown in fig. 1, the support pedestal 325 is a box that is open at the top to allow the bottom-located standby sample consumable 326 (i.e., the standby sample consumable 326 closest to the support pedestal 325) to extend into the interior of the support pedestal 325 through the top opening to avoid interference. In addition, the bottom standby sample consumable 326 rests on the top circumferential edge of the support pedestal 325, and then the other standby sample consumables 326 are sequentially stacked on the bottom standby sample consumable 326.
With continued reference to FIG. 3, in one or more embodiments, each stack module 32 further includes a detection device 324. The detection device 324 is used to detect the height of the standby sample consumable 326 within the chamber 323. In one or more embodiments, a detecting device 324 corresponding to the height of each layer of standby sample consumable 326 is disposed on the first limiting post 3221 of the left limiting plate 322a, so as to detect whether the standby sample consumable 326 with the corresponding height is used. The number of test devices 324 in the stacking module 32 for placement of different types of standby sample consumables 326 varies. When the height of the spare sample consumables 326 is higher, the number of layers of the corresponding type of spare sample consumables 326 that can be stacked on the stacking module 32 is reduced, and the number of detection devices 324 in the stacking module 32 is correspondingly reduced. In addition, the detection device 324 is in communication with the controller of the sample processing device 1, so as to transmit the detection result to the controller, and further control the movement of the transfer module 33.
As shown in fig. 1, in one or more embodiments, the transport module 33 includes a three-dimensional platform 331 and a robot 332. The three-dimensional platform 331 is fixed to the support riser 12. The manipulator 332 is movably fixed to the three-dimensional platform 332 by a driving motor (not shown). In one or more embodiments, the three-dimensional platform 331 includes an X-directional slide rail 3311, a Y-directional slide rail 3312, and a Z-directional slide rail 3311. Based on the orientation shown in fig. 1, the X-direction slide rail 3311 is fixed to the top of the left and right support risers 121 and 122 of the base frame 10 and extends in the substantially right-left direction. The Y-direction slide rail 3312 extends generally in the front-to-rear direction, and the rear end of the Y-direction slide rail 3312 is slidably fixed to the X-direction slide rail 3311. The Z-slide rail 3313 extends substantially in the up-down direction, and a middle portion of the Z-slide rail 3313 is slidably fixed to the Y-slide rail 3312. The robot 332 is movably secured to the Z-slide rail 3313 of the three-dimensional platform 331. That is, the robot 332 may move up and down along the Z-direction slide rail 3313 by driving of the driving motor. Thus, with the above arrangement, the robot 332 can flexibly move in the left-right direction, the front-rear direction, and the up-down direction to grasp and transfer the standby sample consumable 326. In one or more embodiments, the manipulator 332 includes a mechanical jaw 3321 for grasping the sample consumable 23 and the standby sample consumable 326. The mechanical clamping jaw 3321 can be opened and closed under the drive of a motor so as to grasp and put down the consumable.
As shown in fig. 1, in one or more embodiments, the sample processing device 1 of the present invention further comprises a code scanner 40. The scanner 40 may scan the information code disposed on the standby sample consumable 326 to obtain the type of the standby sample consumable 326, facilitating the transfer module 33 to accurately identify the standby sample consumable 326 that matches the depleted sample consumable 23. In one or more embodiments, a scanner mounting plate 3322 is provided on the mechanical clamping jaw 3321 and a scanner 40 is mounted on the scanner mounting plate 3322 to conveniently and accurately scan the information code on the spare sample consumable 326.
When the sample processing device 1 of the present invention is in use, the sensing module 31 arranged on the sample processing module 22 will detect in real time whether the sample consumable 23 is spent. When the sensing module 31 detects that the sample consumable 23 is spent, the controller will drive the transport module 33 to move to the area where the stacking module 32 is located. The scanner 40 will scan and identify the information code on the spare sample consumable 326. When the controller receives the scan result, it will compare whether the spare sample consumable 326 matches the used sample consumable 23. If the result is negative, the transfer module 33 will continue to move to other stacking modules 32; if so, the transfer module 33 will be positioned at the stack module 32. Next, the detecting device 324 on the stacking module 32 will detect the standby sample consumable 326 stacked on the uppermost layer of the fixing base 321, so as to drive the manipulator 332 of the transferring module 33 to accurately grasp the standby sample consumable 326. After the standby sample consumable 326 is grasped, the manipulator 332 will transfer the standby sample consumable 326 to the corresponding sample processing module 20 under the control of the controller to replace the sample consumable 326.
Thus far, the technical solution of the present invention has been described in connection with the preferred embodiments shown in the drawings, but it is easily understood by those skilled in the art that the scope of protection of the present invention is not limited to these specific embodiments. Equivalent modifications and substitutions for related technical features may be made by those skilled in the art without departing from the principles of the present invention, and such modifications and substitutions will fall within the scope of the present invention.

Claims (10)

1. A sample processing device, the sample processing device comprising:
a base frame;
a sample processing module disposed on the pedestal;
a consumable management assembly including a sensing module disposed on each of the sample processing modules to detect whether sample consumables located therein are spent, a stacking module disposed on the pedestal and including a plurality of spare sample consumables, and a transport module movably secured to the pedestal and
when the sensing module detects that the corresponding sample consumable in the sample processing module is exhausted, the transfer module is configured to grasp and transfer a piece of the standby sample consumable onto the sample processing module to replace the exhausted sample consumable.
2. The sample processing device of claim 1, wherein the sample processing module comprises a mounting plate and a sample processing component removably disposed on the mounting plate, and the perception module is secured to the mounting plate.
3. The sample processing device of claim 2, wherein a plurality of spring tabs and a plurality of fixing posts are provided on the mounting plate, the plurality of spring tabs and the plurality of fixing posts being spaced apart from each other along a circumferential direction of the mounting plate and together enclosing a mounting area that can constrain the sample processing component.
4. The sample processing device of claim 1, wherein the transport module comprises:
the three-dimensional platform is fixed on the base frame; and
and the manipulator is movably fixed on the three-dimensional platform and is configured to grasp the sample consumable and the standby sample consumable.
5. The sample processing device according to claim 4, wherein a scanner for scanning an information code of the standby sample consumable is further provided on the robot to acquire the type of the standby sample consumable.
6. The sample processing device of claim 5, wherein the manipulator comprises a mechanical jaw for holding the standby sample consumable and a scanner mounting plate is provided on the mechanical jaw for mounting the scanner.
7. The sample processing device of claim 1, wherein said stacking module comprises:
a fixed base disposed on the base frame;
and a limiting plate configured to extend vertically upward along a circumferential edge of the stationary base so as to define, with the stationary base, a chamber containing the standby sample consumable.
8. The sample processing device according to claim 7, wherein the stopper plate includes a left stopper plate and a right stopper plate disposed opposite to each other on both sides of the stationary base, and each of the left stopper plate and the right stopper plate is a U-shaped member with an opening upward.
9. Sample processing device according to claim 7 or 8, wherein detection means are provided on the limiting plate to detect the height of the standby sample consumable in the chamber.
10. The sample processing device of claim 1, wherein said sample consumable and said standby sample consumable comprise a gun head, a shallow well plate, a PCR plate, and a deep well plate, respectively.
CN202310463612.3A 2023-04-26 2023-04-26 Sample processing device Pending CN116461997A (en)

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Application Number Priority Date Filing Date Title
CN202310463612.3A CN116461997A (en) 2023-04-26 2023-04-26 Sample processing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310463612.3A CN116461997A (en) 2023-04-26 2023-04-26 Sample processing device

Publications (1)

Publication Number Publication Date
CN116461997A true CN116461997A (en) 2023-07-21

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Application Number Title Priority Date Filing Date
CN202310463612.3A Pending CN116461997A (en) 2023-04-26 2023-04-26 Sample processing device

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117245634A (en) * 2023-11-15 2023-12-19 云南师范大学 Six-degree-of-freedom high-precision mechanical arm

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117245634A (en) * 2023-11-15 2023-12-19 云南师范大学 Six-degree-of-freedom high-precision mechanical arm
CN117245634B (en) * 2023-11-15 2024-01-23 云南师范大学 Six-degree-of-freedom high-precision mechanical arm

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