CN116448853A - Disposable self-sensing signal test piece and electrochemical sensing method - Google Patents
Disposable self-sensing signal test piece and electrochemical sensing method Download PDFInfo
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- CN116448853A CN116448853A CN202210007653.7A CN202210007653A CN116448853A CN 116448853 A CN116448853 A CN 116448853A CN 202210007653 A CN202210007653 A CN 202210007653A CN 116448853 A CN116448853 A CN 116448853A
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- processing unit
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- electrochemical processing
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- signal
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- 238000012360 testing method Methods 0.000 title claims abstract description 49
- 238000000034 method Methods 0.000 title claims description 10
- 238000001514 detection method Methods 0.000 claims abstract description 90
- 238000012545 processing Methods 0.000 claims abstract description 62
- 230000005540 biological transmission Effects 0.000 claims abstract description 38
- 238000003487 electrochemical reaction Methods 0.000 claims abstract description 9
- 230000003213 activating effect Effects 0.000 claims description 10
- 239000000758 substrate Substances 0.000 claims description 9
- 230000004913 activation Effects 0.000 claims description 5
- 239000010410 layer Substances 0.000 claims description 4
- 239000011241 protective layer Substances 0.000 claims description 4
- 239000003990 capacitor Substances 0.000 claims description 3
- 239000012491 analyte Substances 0.000 description 8
- 239000012530 fluid Substances 0.000 description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000000835 electrochemical detection Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000002985 plastic film Substances 0.000 description 2
- 229920006255 plastic film Polymers 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229910002651 NO3 Inorganic materials 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000013566 allergen Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 150000003278 haem Chemical class 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
Abstract
The application provides a disposable self-sensing signal test piece, which comprises a test piece body, wherein the test piece body is provided with a detection area and a circuit area, and the detection area is provided with a detection circuit; the test piece body is provided with an electrochemical processing unit, a wireless transmission unit and a power supply unit, wherein the electrochemical processing unit is arranged in the circuit area, the detection circuit is electrically connected with the electrochemical processing unit, the electrochemical processing unit is used for sending a control signal for executing detection to the detection circuit, the detection circuit is used for carrying out electrochemical reaction with the sample to be detected after receiving the control signal and feeding back a feedback signal to the electrochemical processing unit, the electrochemical processing unit is used for converting the feedback signal into a detection parameter signal and sending the detection parameter signal to a receiving element through the wireless transmission unit, and the power supply unit is used for supplying power to the electrochemical processing unit and the wireless transmission unit.
Description
Technical Field
The application relates to an electrochemical sensing test piece and a sensing method.
Background
Electrochemical sensors (Electrochemical Sensor) have been developed for use in the detection of various fluids. The existing electrochemical sensor is equipped differently according to different requirements, but the basic architecture of the existing electrochemical sensor does not include: a container for containing a fluid to be tested, a chemical Reagent (Reagent) for generating an electrochemical reaction with an analyte of the fluid to be tested and generating an output signal of an electrical parameter, a plurality of test electrodes including a working electrode (Working Electrode), a reference electrode (Reference Electrode) and a detection electrode (Detecting Electrode), and a measuring device for providing the necessary working voltage, receiving the output signal and measuring a measurement value to represent the content of the analyte.
In the prior art, the chemical reagent and the test electrode are usually in the form of a sensing test strip, and the measuring device is in the form of a separate measuring instrument, so in order to perform the detection, the user must prepare the measuring instrument and the sensing test strip matched with the measuring instrument, the convenience in use is not enough, and different measuring instruments must be prepared for different detection targets, and the selling price of the measuring instrument is far higher than that of the sensing test strip, which significantly increases the cost burden for the user who needs to detect multiple detection targets at the same time, and the carrying is also inconvenient.
Problems such as these result in the difficulty of popularization of the existing electrochemical sensor, and many users with potential needs do not use the electrochemical sensor because of expensive price, insufficient convenience in use, difficulty in carrying, and the like.
Disclosure of Invention
The technical problem to be solved in the present application is to provide a sensing strip and a sensing method capable of greatly improving convenience.
In order to achieve the above and other objects, the present invention provides a disposable self-sensing signal test strip, comprising a test strip body having a detection area for contacting a sample to be detected and a circuit area for not contacting the sample to be detected, wherein the detection area has a detection circuit; the test piece body is further provided with an electrochemical processing unit, a wireless transmission unit and a power supply unit which are arranged in the circuit area, the detection circuit is electrically connected with the electrochemical processing unit, the electrochemical processing unit is used for sending a control signal for executing detection to the detection circuit, the detection circuit is used for carrying out electrochemical reaction with the sample to be detected after receiving the control signal and feeding back a feedback signal to the electrochemical processing unit, the electrochemical processing unit is further used for converting the feedback signal into a detection parameter signal and sending the detection parameter signal to a receiving element which is not mechanically connected with the disposable self-sensing signal test piece through the wireless transmission unit, and the power supply unit is used for supplying power to the electrochemical processing unit and the wireless transmission unit.
In order to achieve the above and other objects, the present invention provides a disposable self-sensing signal test strip, which mainly comprises a substrate, a detection circuit, an electrochemical processing unit, a wireless transmission unit, a power supply unit, a protection layer and a power supply activating means, wherein the substrate has a detection area for contacting a sample to be detected and a circuit area for not contacting the sample to be detected, the detection circuit, the electrochemical processing unit and the power supply unit are all arranged in the circuit area, the electrochemical processing unit is electrically connected with the detection circuit, the power supply unit is used for supplying power to the electrochemical processing unit and the wireless transmission unit, the protection layer completely covers the circuit area, the electrochemical processing unit, the wireless transmission unit and the power supply unit, and the power supply activating means is used for enabling a user to selectively activate the power supply unit to supply power to the electrochemical processing unit and the wireless transmission unit; the electrochemical processing unit is used for sending a control signal for executing detection to the detection circuit, the detection circuit is used for carrying out electrochemical reaction with the sample to be detected after receiving the control signal and feeding back a feedback signal to the electrochemical processing unit, and the electrochemical processing unit is further used for converting the feedback signal into a detection parameter signal and sending the detection parameter signal to a receiving element which is not mechanically connected with the disposable self-sensing signal test piece through the wireless transmission unit.
In order to achieve the above and other objects, the present invention also provides an electrochemical sensing method, which uses the disposable self-sensing signal test strip, and sequentially comprises the following steps:
activating the power supply unit to supply power to the electrochemical processing unit and the wireless transmission unit by using the power supply activating means;
sending a control signal for executing detection to the detection circuit by using the electrochemical processing unit;
after the detection circuit receives the control signal, the detection circuit is utilized to perform electrochemical reaction with the sample to be detected, and a feedback signal is fed back to the electrochemical processing unit;
converting the feedback signal into a detection parameter signal by using the electrochemical processing unit; and
the electrochemical processing unit is used for transmitting the detection parameter signal to a receiving element which is not mechanically connected with the disposable self-sensing signal test piece through the wireless transmission unit.
Based on the above design, the user can generate and send out the detection parameter signal without using a disposable test piece, and the test piece can be directly used without being mechanically connected with other external hard equipment, and the selling price can be still controlled to be far lower than that of the existing measuring instrument, so that the problem that the electrochemical sensor field is not easy to popularize for a long time is solved, and more potential users can execute electrochemical detection with potential requirements, such as health-related detection, with low cost.
Other details of the other functions and embodiments of the present application are described below with reference to the drawings.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are required to be used in the embodiments or the description of the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present application, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a block diagram of one embodiment of the present application;
fig. 2 is a schematic diagram of one embodiment of the present application.
Symbol description
1: disposable self-sensing signal test piece 2: receiving element
3: power supply activating means 4: display device
10: detection zone 11: detection circuit
20: circuit area 30: electrochemical treatment unit
40: wireless transmission unit 50: power supply unit
60: substrate 70: protective layer
Detailed Description
The positional relationship described in the following embodiments includes: the upper, lower, left and right, unless otherwise indicated, are relative to the orientation of the elements shown in the drawings.
Referring to fig. 1 and 2, an embodiment of the present invention is shown, in which a disposable self-sensing signal test strip 1 can be used for detecting various fluids, and is used for detecting whether a sample to be detected contains a target analyte, a concentration of the target analyte and/or other required detection values, wherein the sample to be detected can be, but is not limited to, blood, urine, a water sample or other non-aqueous fluid samples, and the target analyte can be, but is not limited to, glycosylated heme, blood sugar, heavy metal, nitrate, nitrite, allergen, formaldehyde, dissolved oxygen and other chemical parameters, and the required detection values can be, but are not limited to, acid-base number, conductivity and other physical parameters. The disposable self-sensing signal strip 1 may be used in combination with a receiving element 2 that is not mechanically connected to the disposable self-sensing signal strip 1, the mechanical connection being a physical direct contact between the two components, the receiving element 2 being, but not limited to, a mobile phone, a tablet computer, a computer or other device that can form a wireless connection with the disposable self-sensing signal strip 1 and display, process and/or relay the signal of the detected parameter.
The disposable self-sensing signal test strip 1 comprises a test strip body and a power supply activating means 3, wherein the test strip body is provided with an electrochemical processing unit 30, a wireless transmission unit 40, a power supply unit 50, a substrate 60 and a protection layer 70. The substrate 50 has a detection zone 10 for contacting the sample to be detected and a circuit zone 20 for not contacting the sample to be detected, i.e., the detection zone and the circuit zone are present in the body of the test strip. The detection area 10 is provided with a detection circuit 11, and the detection circuit 11 is electrically connected with the electrochemical processing unit 30; depending on the target analyte or value to be detected, detection circuitry 11 may include, but is not limited to, a working electrode, a reference electrode, an auxiliary electrode, and/or a detection electrode; also, depending on the target analyte or the value to be detected, at least a portion of detection circuitry 11 may include, but is not limited to, a chemical reagent, enzyme, catalyst, and/or enzyme attached to the electrical conductor that facilitates detection of the target analyte or the value to be detected.
The electrochemical processing unit 30, the wireless transmission unit 40 and the power supply unit 50 are disposed in the circuit area 20, and the protective layer 70 completely covers the circuit area 20, the electrochemical processing unit 30, the wireless transmission unit 40 and the power supply unit 50, and the protective layer 70 is, for example, a power supply rim body and has air/water tightness. The electrochemical processing unit 30 may be, for example and without limitation, a microprocessor, the wireless transmission unit 40 may be, for example and without limitation, a bluetooth transmission chip, and the power supply unit 50 may be a capacitor, a fuel cell or other rechargeable or non-rechargeable micro-battery for supplying power to the electrochemical processing unit 30 and the wireless transmission unit 40. In a possible embodiment, the disposable self-sensing signal test strip can be recycled after the first use, and in particular, the rechargeable battery of the disposable self-sensing signal test strip can be recycled for other new or recycled test strip bodies.
The power activation means 3 is used for enabling a user to selectively activate the power supply capability of the power supply unit 50 for supplying power to the electrochemical processing unit 30 and the wireless transmission unit 40, that is, the power supply capability of the power supply unit 50 is activated, the power supply unit 50 can supply power to the electrochemical processing unit 30 and the wireless transmission unit 40; conversely, when the power supply capability of the power supply unit 50 is not activated, the power supply unit 50 cannot supply power to the electrochemical processing unit 30 and the wireless transmission unit 40 to retain the power. The power supply activating means 3 is, for example, a plastic film that can block the power supply unit 50 from other circuits, thereby temporarily disabling the power supply unit 50 from supplying power; when the plastic film is removed, the power supply unit 50 contacts the circuit and resumes the power supply capability. In other possible embodiments, the power activation means may be, but is not limited to, a switch, a knob; in other possible embodiments, the power activation means is an action of placing the power unit into the test strip body.
In order to reduce the cost of the disposable self-sensing signal test strip, the disposable self-sensing signal test strip is particularly free of a gold finger for forming mechanical connection with an external detector and a display for displaying the detection parameter signal.
The disposable self-sensing signal test strip can be applied to an electrochemical sensing method, and the method sequentially comprises the following steps:
the ability of the power supply unit 50 to supply power to the electrochemical processing unit 30 and the wireless transmission unit 40 is activated by the power supply activation means 3;
sending out a control signal for performing detection to the detection circuit 11 by means of the electrochemical processing unit 30;
after the detection circuit 11 receives the control signal, the detection circuit 11 is utilized to perform electrochemical reaction with the sample to be detected, and a feedback signal is fed back to the electrochemical processing unit 30;
converting the feedback signal into a detection parameter signal by the electrochemical processing unit 30; and
the electrochemical processing unit 30 is utilized to transmit the detection parameter signal to the receiving element 2 which is not mechanically connected with the disposable self-sensing signal test piece through the wireless transmission unit 40;
the detected parameter signal is displayed on a display 4 of the receiving unit 2.
Based on the above design, the user can generate and send out the detection parameter signal without using a measuring instrument, and can receive and display the detection parameter signal by using the existing personal devices such as mobile phones or tablet computers of the user, and the test piece can be directly used without being mechanically connected with other external hard equipment, and the selling price can be still controlled to be far lower than that of the existing measuring instrument, thereby solving the long-standing problem of difficult popularization in the field of electrochemical sensors, and enabling more potential users to perform electrochemical detection with potential demands, such as health-related detection, with low cost.
The above examples and/or embodiments are merely for illustrating the preferred examples and/or embodiments for implementing the technology of the present application, and are not limited in any way to the embodiments of the technology of the present application, and any person skilled in the art should be able to make some changes or modifications to other equivalent examples without departing from the scope of the technical means disclosed in the present application, but should still consider the technology or examples substantially identical to the present application.
Claims (10)
1. A disposable self-sensing signal strip, comprising:
the test piece body is provided with a detection area for contacting a sample to be detected and a circuit area for not contacting the sample to be detected, wherein the detection area is provided with a detection circuit; the test piece body is further provided with an electrochemical processing unit, a wireless transmission unit and a power supply unit which are arranged in the circuit area, the detection circuit is electrically connected with the electrochemical processing unit, the electrochemical processing unit is used for sending a control signal for executing detection to the detection circuit, the detection circuit is used for carrying out electrochemical reaction with the sample to be detected after receiving the control signal and feeding back a feedback signal to the electrochemical processing unit, the electrochemical processing unit is further used for converting the feedback signal into a detection parameter signal and sending the detection parameter signal to a receiving element which is not mechanically connected with the disposable self-sensing signal test piece through the wireless transmission unit, and the power supply unit is used for supplying power to the electrochemical processing unit and the wireless transmission unit.
2. The disposable self-sensing signal test strip of claim 1, wherein the test strip body has a substrate, the detection area and the circuit area are both disposed on the substrate, and the electrochemical processing unit, the wireless transmission unit and the power supply unit are all disposed on the substrate.
3. The disposable self-sensing signal test strip of claim 1, wherein said power supply unit is a capacitor.
4. The disposable self-sensing signal test strip of claim 1, wherein said test strip body further comprises a protective layer entirely covering said circuit area, said electrochemical processing unit, said wireless transmission unit and said power supply unit.
5. The disposable self-sensing signal strip of claim 1, wherein the disposable self-sensing signal strip is free of a finger for mechanically connecting to an external detector and a display for displaying the detection parameter signal.
6. The disposable self-sensing signal strip of claim 1, further comprising a power activation means for enabling a user to selectively activate the power unit's ability to supply power to the electrochemical processing unit and the wireless transmission unit.
7. A disposable self-sensing signal test strip, which is characterized by mainly comprising the following components:
a substrate having a detection area for contacting a sample to be detected and a circuit area for not contacting the sample to be detected;
the detection circuit is arranged in the detection area;
the electrochemical processing unit is arranged in the circuit area and is electrically connected with the detection circuit;
the wireless transmission unit is arranged in the circuit area;
the power supply unit is arranged in the circuit area and used for supplying power to the electrochemical processing unit and the wireless transmission unit;
a protection layer which completely covers the circuit area, the electrochemical processing unit, the wireless transmission unit and the power supply unit; and
a power source activating means for enabling a user to selectively activate the power source unit's ability to supply power to the electrochemical processing unit and the wireless transmission unit;
the electrochemical processing unit is used for sending a control signal for executing detection to the detection circuit, the detection circuit is used for carrying out electrochemical reaction with the sample to be detected after receiving the control signal and feeding back a feedback signal to the electrochemical processing unit, and the electrochemical processing unit is further used for converting the feedback signal into a detection parameter signal and sending the detection parameter signal to a receiving element which is not mechanically connected with the disposable self-sensing signal test piece through the wireless transmission unit.
8. The disposable self-sensing signal strip of claim 7, wherein the power supply unit is a capacitor.
9. An electrochemical sensing method using the disposable self-sensing signal test strip according to any one of claims 6 to 8, comprising the following steps in order:
activating the power supply unit to supply power to the electrochemical processing unit and the wireless transmission unit by using the power supply activating means;
sending a control signal for executing detection to the detection circuit by using the electrochemical processing unit;
after the detection circuit receives the control signal, the detection circuit is utilized to perform electrochemical reaction with the sample to be detected, and a feedback signal is fed back to the electrochemical processing unit;
converting the feedback signal into a detection parameter signal by using the electrochemical processing unit; and
the electrochemical processing unit is used for transmitting the detection parameter signal to a receiving element which is not mechanically connected with the disposable self-sensing signal test piece through the wireless transmission unit.
10. The electrochemical sensing method of claim 9, further comprising the steps of:
and displaying the detection parameter signal on a display of the receiving element.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210007653.7A CN116448853A (en) | 2022-01-05 | 2022-01-05 | Disposable self-sensing signal test piece and electrochemical sensing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210007653.7A CN116448853A (en) | 2022-01-05 | 2022-01-05 | Disposable self-sensing signal test piece and electrochemical sensing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116448853A true CN116448853A (en) | 2023-07-18 |
Family
ID=87120643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210007653.7A Pending CN116448853A (en) | 2022-01-05 | 2022-01-05 | Disposable self-sensing signal test piece and electrochemical sensing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116448853A (en) |
-
2022
- 2022-01-05 CN CN202210007653.7A patent/CN116448853A/en active Pending
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