CN116439821A

CN116439821A - Multi-needle steep pulse ablation electrode device, radio frequency ablation device, method and system

Info

Publication number: CN116439821A
Application number: CN202310700671.8A
Authority: CN
Inventors: 陈强; 王志青; 邵文煜; 郑书琪
Original assignee: Zhejiang Curaway Medical Technology Co ltd
Current assignee: Zhejiang Curaway Medical Technology Co ltd
Priority date: 2023-06-14
Filing date: 2023-06-14
Publication date: 2023-07-18
Anticipated expiration: 2043-06-14
Also published as: CN116439821B

Abstract

The invention discloses a multi-needle steep pulse ablation electrode device, a radio frequency ablation device, a method and a system, wherein a plurality of energy application units are configured to be inserted into and connected to the far end surface of a handheld shell in a sliding mode along a preset track, a driving part is arranged in the handheld shell, and each energy application unit is driven by the driving part to slide on the far end surface of the handheld shell along the preset track, so that the distance between each energy application unit and the area of an energy application execution area formed by matching the execution ends of each energy application unit are adjusted to adapt to the preset energy application area of energy required to be applied by a target tumor, and the problem that the distance between needles and the ablation area are difficult to accurately control in the conventional steep pulse ablation electrode is solved. After the energy is adjusted to fit the target tumor, the execution end of the energy application unit can reach the target tumor to apply energy in a conveying or penetrating mode, so that the target tumor in the energy application execution area is subjected to steep pulse ablation.

Description

Multi-needle steep pulse ablation electrode device, radio frequency ablation device, method and system

Technical Field

The invention belongs to the technical field of medical equipment, and particularly relates to a multi-needle steep pulse ablation electrode device, a radio frequency ablation device, a method and a system.

Background

At present, the treatment methods of cancers mainly comprise operation treatment, radiation treatment, chemotherapy and the like, but the traditional treatment methods are limited by factors such as indication, contraindications, side effects and the like, so the treatment effect is still not ideal, and therefore, the search for new treatment methods of cancers is always an important subject in the medical field and the biomedical engineering field.

Recent studies have found that after electroporation, the cell will undergo irreversible electrical breakdown of the cell membrane with increasing pulse intensity and increasing pulse duration, causing cell membrane rupture until cell death. By utilizing the characteristic, researchers propose irreversible electroporation therapy, which is a novel non-thermal tumor ablation means, wherein electric pulses are applied to cancer tissues to cause irreversible electric breakdown of cancer cells, so that the survival condition of the cancer cells is destroyed, and the purpose of killing the cancer cells is achieved. However, the steep pulse ablation electrodes currently on the market have several problems: first, steep pulse ablation electrodes require multiple electrodes to be used in combination during treatment, but it is difficult to ensure parallelism between the electrodes or that the electrodes are in the same plane during the procedure. Second, the spacing between the steep pulse ablation electrodes cannot be precisely controlled, and the electrode spacing can affect the range of the electric field covering the tumor and the field intensity distribution during treatment, thereby affecting the ablation effect. Thirdly, during treatment, the ablation area cannot be changed at will according to the size or shape of the focus, and the puncture position or the model of the electrode is changed to completely ablate, so that the difficulty of operation is increased and the operation time is prolonged.

Disclosure of Invention

In order to solve the problems, the invention provides a multi-needle steep pulse ablation electrode device, a radio frequency ablation device, a method and a system, which are used for solving the problems that the prior steep pulse ablation electrode is difficult to accurately control the distance between needles and the ablation area, and the technical scheme is as follows:

the invention provides a multi-needle steep pulse ablation electrode device, which defines a region to which energy is applied for target tissue as a preset energy application region, and comprises the following components:

a hand-held housing;

the energy application units are respectively configured to be inserted into and slidingly connected to the far-end surface of the handheld shell along a preset track, and the execution ends of the energy application units are positioned on the same plane and cooperate to form an energy application execution area;

the driving part is arranged in the handheld shell, the power input end of the driving part extends out of the handheld shell, and the power output end of the driving part is respectively connected with the plurality of energy applying units;

the driving part is configured to receive external power input from the power input end, and to output driving force from the power output end to drive the plurality of energy application units to slide along the preset tracks corresponding to the energy application units respectively so as to adjust the energy application execution area to be matched with the preset energy application area.

In the multi-needle steep pulse ablation electrode device of the invention, the preset trajectories of the plurality of energy application units are configured to converge toward and/or diverge outwardly from the center of the distal end face of the handpiece.

The multi-needle steep pulse ablation electrode device of the invention, the shape of the energy application execution area is configured as a regular polygon.

The multi-needle steep pulse ablation electrode device provided by the invention is characterized in that the direction vertical to the far end surface of the handheld shell is defined as vertical, and the direction parallel to the far end surface of the handheld shell is defined as horizontal;

the driving part comprises a power input unit, a power execution unit and a plurality of connecting sliding units; the connecting sliding units are respectively connected with the corresponding energy applying units and are connected with the inner cavity of the handheld shell in a sliding manner along the preset track; the output end of the power input unit extends into the inner cavity of the handheld shell and is connected to each connecting sliding unit through the power executing unit in a transmission way; the power execution unit is configured to receive a power input of the power input unit and convert the power input to drive each of the connection slide unit and the energy application unit to slide laterally.

The power input unit is a vertical power input mechanism, the power execution unit comprises a vertical sliding block and an elastic force supply unit, and the connecting sliding unit is a transverse sliding block provided with a guide inclined plane;

the input end of the vertical power input mechanism extends out of the handheld shell, and the output end of the vertical power input mechanism is connected with the vertical sliding block and is used for driving the vertical sliding block to vertically move; a plurality of driving inclined planes which are arranged in a surrounding manner are arranged on the vertical sliding block, and the driving inclined planes incline towards the center of the far end face of the handheld shell; the plurality of transverse sliding blocks are arranged on the periphery of the vertical sliding blocks in a surrounding mode, and the driving inclined planes correspond to the guiding inclined planes one by one; the elastic force supply unit is respectively connected with each transverse sliding block and is used for providing elastic force of the transverse sliding blocks towards the vertical sliding blocks;

under the drive of the elastic force supply unit, the guide inclined plane of each transverse sliding block is attached to the drive inclined plane, and the transverse position of the transverse sliding block relative to the vertical sliding block is adjusted along the preset track by the vertical relative position change of the vertical sliding block.

The invention relates to a multi-needle steep pulse ablation electrode device, wherein a vertical power input mechanism comprises a rotating piece, an adjusting screw and a fixing nut;

the fixing nut is fixed on the vertical sliding block; the adjusting screw is vertically arranged and is in threaded connection with the fixing nut; the rotating piece is fixed at one end of the adjusting screw rod and extends out of the handheld shell.

The invention relates to a multi-needle steep pulse ablation electrode device, wherein a rotating piece comprises a knob and a vertical elastic piece; the bottom end of the knob is provided with an extension boss extending outwards and used for being abutted to the proximal end face of the handheld shell; and two ends of the vertical elastic piece are respectively connected with the extension boss and the vertical sliding block.

The elastic force supply unit is an annular compression spring;

and one side of each transverse sliding block, which is away from the center of the distal end face of the handheld shell, is provided with an elastic piece groove, and the annular compression spring surrounds each transverse sliding block and is embedded into the corresponding elastic piece groove.

The invention relates to a multi-needle steep pulse ablation electrode device, wherein a vertical sliding block comprises a sliding block body, a vertical guide structure and a plurality of inclined guide structures, wherein the vertical guide structure and the inclined guide structures are arranged on the sliding block body;

The outer contour of the vertical guide structure is attached to the wall surface of the inner cavity of the handheld shell; the oblique guide structure comprises two guide plates which are vertically arranged on the sliding block body at intervals, the lower ends of the two guide plates are respectively provided with an oblique tangential plane facing the center of the far end surface of the handheld shell, and the two corresponding oblique tangential planes are combined to form the driving inclined plane;

the upper end of the transverse sliding block is provided with a protruding structure, and two sides of the protruding structure are respectively provided with an inclined step surface matched with the guide inclined surface.

According to the multi-needle steep pulse ablation electrode device, the transverse sliding block is internally provided with the embedded through grooves which are vertically arranged and extend to the protruding structures.

According to the multi-needle steep pulse ablation electrode device, the lower end of the transverse sliding block is provided with the extension sliding table extending towards at least one side of the preset track;

the far end face of the handheld shell is of a far end bottom plate structure, and the far end bottom plate structure comprises a chassis and a cover plate; the chassis is respectively provided with a guide groove corresponding to each preset track, and the width of the guide groove is matched with the whole size of the extension sliding table; the bottom surface of the guide groove is provided with a strip-shaped through groove for the energy applying unit to pass through; the cover plate is covered on the chassis and provided with guide openings corresponding to the guide grooves one by one, and the width of the guide openings is matched with that of the transverse sliding blocks.

According to the multi-needle steep pulse ablation electrode device, the chassis and the cover plate are respectively provided with the extending openings for enabling the vertical sliding block to extend in.

According to the multi-needle steep pulse ablation electrode device, the power input unit is a rotating piece, the power execution unit is a plurality of intermediate transmission pieces, and the connecting sliding unit is a transverse sliding block;

the first ends of the plurality of intermediate transmission pieces are respectively connected with the rotating piece in a rotating way and are offset to the rotating axis of the rotating piece, and at least part of the rotating pieces extend out of the handheld shell; the second end of the middle transmission piece is rotationally connected with the transverse sliding block;

the far end surface of the handheld shell is a chassis, a plurality of long strip-shaped through grooves for the energy applying unit to pass through are formed in the chassis, and the track of the long strip-shaped through grooves is the preset track; the transverse sliding blocks slide on the chassis, and the energy applying units are clamped on the transverse sliding blocks and extend out of the corresponding long strip-shaped through grooves.

The multi-needle steep pulse ablation electrode device comprises a power input unit, a power execution unit, a connecting sliding unit and a connecting sliding unit, wherein the power input unit is a vertical power input mechanism;

The input end of the vertical power input mechanism extends out of the handheld shell, and the output end of the vertical power input mechanism is respectively connected with the first ends of the inclined connecting rods in a rotating and/or swinging manner and is used for driving the first ends of the inclined connecting rods to vertically move; the second ends of the oblique connecting rods are respectively connected with the corresponding transverse sliding blocks in a rotating and/or swinging mode;

The power execution unit further comprises a support connecting rod, wherein the first end of the support connecting rod is connected with the handheld shell in a rotating and/or swinging mode, and the second end of the support connecting rod is connected with a rod body of the oblique connecting rod in a rotating and/or swinging mode.

The invention relates to a multi-needle steep pulse ablation electrode device, wherein a vertical power input mechanism comprises a rotating piece, an adjusting screw rod, a connecting sliding block and a vertical elastic piece;

The adjusting screw is vertically arranged in the handheld shell and is in threaded connection with the proximal end face of the handheld shell, the connecting sliding blocks are rotationally connected with the adjusting screw, and the connecting sliding blocks are respectively connected with the first ends of the inclined connecting rods; the rotating piece is fixed at one end of the adjusting screw rod and extends out of the handheld shell; the two ends of the vertical elastic piece are respectively connected with the handheld shell and the connecting sliding block.

The multi-needle steep pulse ablation electrode device is characterized in that the energy application unit is a metal puncture needle.

The multi-needle steep pulse ablation electrode device of the invention has three or four or five energy application units.

The invention provides a method for using a multi-needle steep pulse ablation electrode assembly for performing ablation of target tissue, comprising:

providing a multi-needle steep pulse ablation electrode assembly: further comprising a handheld housing, a plurality of energy application units, and a drive; the connecting ends of the energy applying units are inserted into and connected with the far-end surface of the handheld shell in a sliding way along a preset track, and the executing ends of the energy applying units are positioned on the same plane and cooperate to form an energy applying executing area; the driving part is arranged in the handheld shell, the power input end of the driving part extends out of the handheld shell, and the power output end of the driving part is respectively connected with the plurality of energy applying units; the driving part is configured to receive external power input from the power input end, and the power output end outputs driving force to drive the plurality of energy applying units to slide along the corresponding preset tracks;

The driving part is configured to receive external power input to drive each energy application unit to slide along a preset track of the energy application unit, so as to obtain the energy application execution area matched with a preset energy application area;

the multi-needle steep pulse ablation electrode device is configured to convey or puncture each energy application unit to a target position corresponding to target tissue;

each of the energy application units is configured to deliver energy to a target tissue.

The invention provides a tumor ablation device, comprising:

a carrier carrying a plurality of treatment units; wherein, the connecting ends of the plurality of treatment units are configured to be inserted into and slidingly connected with the far end surface of the carrier along a preset track, and the executing ends of the treatment units are positioned on the same plane and cooperate to form an energy application executing area;

the driving part is arranged in the carrier, and the power output end of the driving part is respectively connected with each treatment unit; the driving part is configured to drive each treatment unit to slide along the corresponding preset track so as to adjust the energy application execution area to be matched with a preset tumor ablation area.

A medical minimally invasive system of the invention comprises a multi-needle steep pulse ablation electrode assembly as described in any of the above.

By adopting the technical scheme, the invention has the following advantages and positive effects compared with the prior art:

according to the embodiment of the invention, the plurality of energy application units are configured to be inserted into and connected with the far-end surface of the handheld shell in a sliding manner along the preset track, the driving part is arranged in the handheld shell, and each energy application unit is driven by the driving part to slide on the far-end surface of the handheld shell along the preset track, so that the distance between each energy application unit and the area of an energy application execution area formed by matching the execution ends of each energy application unit are adjusted to adapt to the preset energy application area of energy required by a target tumor, and the problem that the distance between needles and the ablation area are difficult to accurately control in the conventional steep pulse ablation electrode is solved. After the energy is adjusted to fit the target tumor, the execution end of the energy application unit can reach the target tumor to apply energy in a conveying or penetrating mode, so that the target tumor in the energy application execution area is subjected to steep pulse ablation.

Drawings

FIG. 1 is a schematic view of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention except for a hand-held housing;

FIG. 2 is a cross-sectional view of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 3 is a schematic view of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 4 is a schematic view of a chassis of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 5 is a schematic view of a cover plate of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 6 is a schematic view of a lateral slider of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 7 is a cross-sectional view of a lateral slider of a multi-needle steep pulse ablation electrode assembly in accordance with a first embodiment of the invention;

FIG. 8 is a schematic view of a vertical slider of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 9 is a cross-sectional view of a vertical slider of a multi-needle steep pulse ablation electrode assembly in accordance with a first embodiment of the invention;

fig. 10 is a schematic diagram of the cooperation of a vertical slider and a horizontal slider of a multi-needle steep pulse ablation electrode device according to the first embodiment of the invention;

FIG. 11 is a cross-sectional view of a vertical slider and a horizontal slider of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 12 is a schematic view of a knob of a multi-needle steep pulse ablation electrode assembly according to a first embodiment of the invention;

FIG. 13 is a cross-sectional view of a knob of a multi-needle steep pulse ablation electrode assembly according to an embodiment of the invention;

fig. 14 is a front view of a multi-needle steep pulse ablation electrode assembly according to a second embodiment of the invention, except for a hand-held housing;

FIG. 15 is a schematic view of a multi-needle steep pulse ablation electrode assembly according to a second embodiment of the invention except for a hand-held housing;

FIG. 16 is a cross-sectional view of a multi-needle steep pulse ablation electrode assembly in accordance with a third embodiment of the invention;

fig. 17 is a schematic view of a multi-needle steep pulse ablation electrode assembly according to a third embodiment of the invention except for a hand-held housing.

Reference numerals illustrate: 1: an energy application unit; 2: a chassis; 201: a guide groove; 202: a strip-shaped through groove; 3: a cover plate; 301: a guide opening; 4: an annular compression spring; 5: a transverse slide block; 501: a guide slope; 502: embedding the through groove; 503: an elastic member groove; 6: a vertical sliding block; 601: a guide plate; 602: a guide interval; 603: a blind hole; 604: a through hole; 7: a vertical elastic member; 8: a knob; 801: a knob threaded hole; 802: semicircular strip grooves; 803: an extension boss; 9: adjusting a screw; 10: a fixing nut; 11: a hand-held housing; 12: a rotating shaft; 13: an intermediate transmission member; 14: the connecting slide block; 15: an oblique connecting rod; 16: and supporting the connecting rod.

Detailed Description

Other advantages and effects of the present invention will become apparent to those skilled in the art from the following disclosure, which describes the embodiments of the present invention with reference to specific examples. The invention may be practiced or carried out in other embodiments that depart from the specific details, and the details of the present description may be modified or varied from the spirit and scope of the present invention. It is to be understood that the terms "center," "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are directional or positional relationships as indicated based on the drawings, merely to facilitate describing the invention and simplify the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus are not to be construed as limiting the invention. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", etc. may explicitly or implicitly include one or more such feature. In the description of the present invention, unless otherwise indicated, the meaning of "a plurality" is two or more.

It should be noted that, unless explicitly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art in a specific case.

In addition, in the description herein, "proximal" and "proximal" of "proximal" are terms commonly used in the medical arts. Specifically, the "proximal end" is an end close to the operator, the "proximal end" is an end face close to the operator, the "distal end" is an end far away from the operator, and the "distal end face" is an end face far away from the operator.

Example 1

Referring to fig. 1 to 13, in one embodiment, a multi-needle steep pulse ablation electrode device defines a region of desired energy application of a target tissue as a preset energy application region, including a hand-held housing 11, a plurality of energy application units 1, and a driving section.

The connection ends of the plurality of energy application units 1 are configured to be inserted into and slidingly connected to the distal end surface of the handheld housing 11 along a preset track, and the execution ends of the plurality of energy application units 1 are located on the same plane and cooperate to form an energy application execution area.

The driving part is arranged in the handheld shell 11, the power input end of the driving part extends out of the handheld shell 11, and the power output end of the driving part is respectively connected with the plurality of energy applying units 1. The driving part is configured such that the power input end receives external power input and outputs driving force from the power output end to drive the plurality of energy application units 1 to slide along preset tracks corresponding to the respective energy application units 1, respectively, so as to adjust the energy application execution area to match the preset energy application area.

In this embodiment, the plurality of energy applying units 1 are configured to be inserted into and slidingly connected to the distal end surface of the handheld housing 11 along a preset track, and a driving portion is disposed in the handheld housing 11, and each energy applying unit 1 is driven by the driving portion to slide on the distal end surface of the handheld housing 11 along the preset track, so that the distance between each energy applying units 1 and the area of the energy applying execution area formed by the execution end of each energy applying unit 1 are adjusted to adapt to the preset energy applying area required by the target tumor, and the problem that the distance between each needle and the ablation area are difficult to accurately control in the conventional steep pulse ablation electrode is solved. After the energy application unit is adjusted to fit the target tumor, the execution end of the energy application unit 1 can reach the target tumor to apply energy in a conveying or penetrating mode, so that the target tumor in the energy application execution area can be subjected to steep pulse ablation.

The specific structure of the multi-needle steep pulse ablation electrode device of this embodiment is further described below:

in the present embodiment, the preset trajectories of the plurality of energy application units 1 described above are configured to converge or diverge outwardly toward the center of the center distal face of the hand-held housing 11. That is, the preset tracks may be set as straight lines, specifically, elongated through grooves 202 formed on the radial lines that diverge outwards from the center point of the distal end surface of the handheld housing 11, where the radial lines of the preset tracks are disposed at equal angles. Of course, in other embodiments, the predetermined trajectory may be provided as a curve or other form, such as a curve that deflects toward a center point around the distal surface along the center point, which is not specifically limited herein.

In the present embodiment, the shape of the energy application execution region may be specifically configured as a regular polygon. I.e. the number of energy applying units 1 is the same as the number of end points of the regular polygon, and adjacent energy applying units 1 are equidistantly arranged with the center point of the distal end face as the center. Wherein the number of the energy applying units 1 is three or four or five or more, which can be specifically determined according to the need.

The direction perpendicular to the distal end face of the hand-held housing 11 is defined as vertical, and the direction parallel to the distal end face of the hand-held housing 11 is defined as lateral.

In this embodiment, the driving part may include a power input unit, a power execution unit, and a plurality of connection sliding units. The connecting sliding units are respectively connected with the corresponding energy applying units 1 and are connected with the inner cavity of the handheld shell 11 in a sliding manner along a preset track. The output end of the power input unit stretches into the inner cavity of the handheld shell 11 and is connected to each connecting sliding unit through the power executing unit in a transmission mode. The power execution unit is configured to receive a power input of the power input unit and convert the power input to drive the respective connection slide units and the energy application unit 1 to slide laterally. The power input unit is a component for receiving external power input, the power executing unit is a power conversion mechanism for converting the input power into driving the connecting sliding unit to slide on the distal end surface, and the connecting sliding unit is used as a component for connecting the energy applying unit 1 and realizing sliding.

Referring to fig. 6 to 11, further, the power input unit of the present embodiment may be a vertical power input mechanism, the power execution unit includes a vertical slider 6 and an elastic force supply unit, and the connection sliding unit may be a lateral slider 5 provided with a guide slope 501.

The input end of the vertical power input mechanism extends out of the handheld shell 11, and the output end of the vertical power input mechanism is connected with the vertical sliding block 6 and is used for outputting vertical driving force and driving the vertical sliding block 6 to vertically move. The plurality of transverse sliders 5 are arranged to be uniformly distributed around the circumference of the vertical slider 6, and the driving inclined surfaces are in one-to-one correspondence with the guiding inclined surfaces 501, and the guiding inclined surfaces 501 are inclined surfaces which face the center of the distal end surface and are inclined downward (the direction of the proximal end surface of the hand-held housing 11 facing the distal end surface is downward). The vertical sliding block 6 is provided with a plurality of driving inclined planes which are arranged in a surrounding manner, are in one-to-one correspondence with the transverse sliding blocks 5, and are parallel to the guiding inclined plane 501 (namely, inclined planes which face the center of the far end face of the handheld shell 11 and face downwards). An elastic force supply unit is connected to each lateral slider 5 for supplying an elastic force for pushing the lateral slider 5 toward the vertical slider 6, that is, in a direction toward the center of the distal end face of the hand-held housing 11.

The guiding inclined plane 501 of each transverse sliding block 5 is attached to the driving inclined plane under the driving of the elastic force supply unit, and the transverse position between the transverse sliding blocks 5 and the vertical sliding blocks 6 is adjusted along the preset track by the vertical relative position change of the vertical sliding blocks 6. The vertical sliding blocks 6 move downwards, namely each transverse sliding block 5 can be pushed outwards, so that the transverse sliding blocks 5 move along a preset track towards the direction deviating from the center of the far end surface of the handheld shell 11; the vertical sliding blocks 6 move upwards to release the limit of the transverse sliding blocks 5 in the transverse direction, and each transverse sliding block 5 moves along the preset track towards the direction close to the center of the far end surface of the handheld shell 11 under the action of the elastic force supply unit until being attached to the vertical sliding blocks 6.

Specifically, the vertical power input mechanism may include a rotator, an adjusting screw 9, and a fixing nut 10. The adjusting screw 9 is vertically arranged and rotatably connected in the inner cavity of the handheld housing 11, and the adjusting screw 9 fixes the nut 10. The rotating member is fixed to one end of the adjusting screw 9 near the proximal end face of the hand-held housing 11 and protrudes from the hand-held housing 11. The fixing nut 10 is screwed to the adjusting screw 9, and the fixing nut 10 is fixed to the vertical sliding block 6, specifically, a blind hole 603 may be formed on a proximal end face (upper end face) of the vertical sliding block 6, the fixing nut 10 may be fixedly disposed in the blind hole 603, and a through hole 604 may be disposed on a bottom surface of the blind hole 603 for allowing the adjusting screw 9 to pass through.

Referring to fig. 12 and 13, in the present embodiment, the turning member comprises a knob 8 and a vertical elastic member 7. The center of the bottom of the knob 8 is provided with a knob 8 threaded hole which is in threaded fit with the adjusting screw 9, and when the knob 8 is rotated, the adjusting screw 9 is also rotated. The outer surface of the knob 8 may be provided with a plurality of semicircular elongated grooves 802 which are uniformly arranged and mainly play a role in skid prevention. Further, the bottom end of the knob 8 is provided with an outwardly extending extension boss 803 for abutting against the proximal end face of the hand-held housing 11 (i.e., an opening is provided in the proximal end face of the hand-held housing 11 that allows the knob 8 to protrude but does not allow the extension boss 803 to protrude). The two ends of the vertical elastic piece 7 are respectively connected with the extending boss 803 and the vertical sliding block 6, so as to maintain the knob 8 to be always abutted against the proximal end face of the handheld shell 11, and the vertical elastic piece 7 can be specifically a compression spring.

When the knob 8 rotates, the adjusting screw 9 is driven to rotate, the fixing nut 10 in threaded connection with the adjusting screw is fixed on the vertical sliding block 6 and cannot rotate, and under the action of threads, the fixing nut 10 can move in the vertical direction, so that the vertical sliding block 6 is driven to move up and down.

Further, the elastic force supply unit may be specifically an annular compression spring 4. Correspondingly, an elastic piece groove 503 is formed on one side of each transverse sliding block 5 away from the center of the distal end face of the handheld housing 11, the annular compression spring 4 surrounds each transverse sliding block 5 and is embedded in the corresponding elastic piece groove 503, and the annular inward contraction force of the annular compression spring is used for providing the elastic force required by the transverse sliding blocks 5.

In this embodiment, the vertical sliding block 6 specifically includes a sliding block body, and a vertical guiding structure and a plurality of oblique guiding structures that are disposed on the sliding block body. The outer contour of the vertical guiding structure is attached to the wall surface of the inner cavity of the handheld shell 11, the inner cavity of the handheld shell 11 can be a cylindrical cavity, and then the outer contour (outer ring surface) of the vertical guiding structure can be round matched with the cylindrical side surface of the cylindrical cavity. The oblique guiding structure may specifically include two guiding plates 601 vertically and at intervals arranged on the slider body, the lower ends of the two guiding plates 601 are both provided with oblique tangential planes facing the center of the distal end face of the handheld housing 11, and the two corresponding oblique tangential planes are combined to form a driving inclined plane.

The upper end of the transverse sliding block 5 is provided with a corresponding protruding structure, and two sides of the protruding structure are respectively provided with an inclined step surface matched with the guide inclined surface 501. That is, in a state where the guide slope 501 is attached to the driving slope, the protruding structure always protrudes into the guide space 602 formed between the two guide plates 601, and the relative positional movement between the lateral slider 5 and the vertical slider 6 can be guided.

Further, in order to ensure sufficient clamping of the energy applying unit 1, the transverse slider 5 is provided with an embedded through groove 502 vertically arranged and extending to the protruding structure, that is, the connecting end of the energy applying unit 1 can be inserted into and extend out of the embedded through groove 502, thereby ensuring a longer clamping length and achieving the purpose of stable clamping.

In this embodiment, in order to guide the lateral slider 5 along the preset track, the lower end of the lateral slider 5 may be provided with an extension slide table extending toward at least one side of the preset track, and may actually be two extension slide tables extending toward two sides of the predicted track (both ends other than the track).

Referring to fig. 4 and 5, the distal surface of the hand-held housing 11 may be a distal base plate structure comprising a base plate 2 and a cover plate 3, which may be threaded. The chassis 2 is provided with a guiding groove 201 corresponding to each preset track, the width of the guiding groove 201 matches the whole size of the extending sliding table, and the bottom surface of the guiding groove 201 is provided with the long strip-shaped through groove 202 for the energy applying unit 1 to pass through. The cover plate 3 is covered on the chassis 2 and is provided with guide openings 301 corresponding to the guide grooves 201 one by one, and the width of the guide openings 301 is matched with that of the transverse sliding blocks 5. Namely, the chassis 2 and the cover plate 3 are matched to form a sliding chamber which is matched with the transverse sliding block 5 and two sides of which extend the sliding table.

Further, since the vertical sliding block 6 in this embodiment slides up and down, interference with the chassis 2 and the cover plate 3 will exist in a part of the scene, and thus the chassis 2 and the cover plate 3 are respectively provided with an extending opening for extending the vertical sliding block 6 for avoiding.

In this embodiment, the energy applying unit 1 may be specifically metal piercing needles, and the plurality of metal piercing needles are electrically connected to the high-voltage pulse power source, where at least one metal piercing needle is an input electrode (for guiding the high-frequency high-voltage pulse current into the energy applying execution area), and at least one metal piercing needle is a recovery electrode (for guiding the high-frequency high-voltage pulse current).

The following describes specific technical means of the present embodiment:

the multi-needle steep pulse ablation electrode device solves the problems that the high-voltage steep pulse treatment technology cannot accurately control the distance between the needles and randomly adjust the ablation area when performing tumor ablation operation, and simultaneously solves the problem that other normal tissues can be damaged when the tumor is resected by the surgical operation.

1. According to the multi-needle steep pulse ablation electrode device, through the cooperation of the transverse sliding block 5 and the guide grooves 201 of the chassis 2 and the upper cover plate 3 and the structure that the embedded through groove 502 of the transverse sliding block 5 for fixing the tail end of each metal puncture needle is perpendicular to the chassis 2, the metal puncture needles are parallel to each other, the movement tracks of the metal puncture needles are in the same plane, the fact that a plurality of metal puncture needles can penetrate the same focus tissue at the same time and are parallel to each other is ensured, the phenomenon that medical staff are required to hold or limit devices to keep the needles parallel to each other in steep pulse ablation operation is solved, the electrode device can enable the needles to be parallel to each other, the problem that other limit devices or medical staff are required to hold the electrodes to ensure the parallelism of the needles in the treatment process is avoided, and the operation difficulty of operation is reduced.

2. According to the multi-needle steep pulse ablation electrode device, the distance between the needles can be accurately controlled through the threaded connection structure of the adjusting screw 9, the knob 8 and the fixing nut 10, the matching of the fixing nut 10 and the blind hole 603 of the vertical sliding block 6 and the matching of the guiding inclined plane 501 and the driving inclined plane, because when the knob 8 rotates one thread, the adjusting screw 9 rotates one thread, the vertical sliding block 6 moves one thread pitch upwards or downwards along with the rotation, and the vertical sliding block 6 pushes the horizontal sliding block 5 to move a certain distance, the distance between the needles can be accurately controlled through the threaded connection structure and the matching of the horizontal sliding block 5 and the vertical sliding block 6, the problem that when a high-voltage steep pulse treatment technology is used for performing surgical ablation, a high-voltage pulse is applied between the two electrodes, the electrode distance can influence the range and the field intensity distribution of a tumor during treatment, so that the ablation effect is influenced can be solved, the range and the field intensity distribution of the electric field can be accurately controlled to cover the tumor, and the effect of complete ablation can be achieved, and other normal tissues can not be damaged.

3. The electrode of the invention can randomly adjust the ablation area of the electrode through the matching of the guide inclined plane 501 and the driving inclined plane and the matching of the elastic piece groove 503 of the transverse sliding block 5 and the annular compression spring 4. When the vertical sliding block 6 moves downwards, the vertical sliding block can push the vertical sliding block to move outwards from the center of the chassis 2, and the ablation area of the electrode is increased; when the vertical sliding block 6 moves upwards, the annular compression spring 4 is tightened, so that the guide inclined plane 501 of the horizontal sliding block 5 is always matched with the driving inclined plane of the vertical sliding block 6, meanwhile, the horizontal sliding block 5 moves towards the center of the chassis 2, the ablation area of the electrode device is reduced, the ablation area of the electrode can be adjusted randomly, the problem that the electrode itself cannot change the ablation area according to the size and shape of a tumor when the tumor is ablated, and the ablation area can be changed only by changing electrodes or puncture positions with different specifications is solved, so that the problem that the tumor is completely ablated is solved, the operation difficulty is reduced, and the flexibility of the electrode in clinical application is improved. Therefore, when in treatment, the ablation area of the electrode can be changed according to the size and shape of the tumor, the effect of complete ablation can be achieved without changing the electrodes with different specifications or changing the puncture position, the operation is simplified, and the operation time is saved.

Meanwhile, the distance between the needle bodies is realized through the thread structure, and when one thread is rotated, the distance between the needle bodies can be changed to a certain extent, namely, the distance between the needle bodies can be accurately controlled through the thread. Therefore, in the operation process, the electric field coverage range and field intensity distribution during treatment cannot be affected due to the fact that the electrode spacing cannot be accurately controlled, and therefore the ablation effect is not affected.

4. The electrode of the invention ablates focus tissues by combining surgical operation and high-voltage steep pulse ablation technology, which solves the problem that other normal tissues are damaged when the focus tissues are resected by surgical operation, solves the problem that the focus tissues cannot be completely ablated due to difficult accurate positioning when the focus tissues are treated by the high-voltage steep pulse ablation technology, and enhances the treatment effect of the operation.

Example two

Referring to fig. 14 and 15, the present embodiment provides a multi-needle steep pulse ablation electrode device based on the first embodiment, and the arrangement form of the driving part is adjusted, specifically as follows:

in this embodiment, the power input unit may be a rotating member, the power executing unit is a plurality of intermediate transmission members 13, and the connecting sliding unit is a transverse sliding block 5.

The first ends of the intermediate transmission members 13 are respectively rotatably connected to a rotating member (the direction of the rotation axis is vertical, which can be specifically realized through the rotating shaft 12), and are offset from the rotation axis of the rotating member, and at least part of the rotating member extends out of the handheld housing 11. The second end of the intermediate transmission member 13 is rotatably connected to the transversal slider 5 (likewise, the direction of the rotation axis is vertical, which can be achieved in particular by means of the rotation shaft 12).

The far end surface of the hand-held shell 11 is a chassis 2, a plurality of long strip-shaped through grooves 202 for enabling the energy applying unit 1 to pass through are arranged on the chassis 2, and the track of the long strip-shaped through grooves 202 is a preset track. The transverse slider 5 slides on the chassis 2, and the energy application unit 1 is clamped on the transverse slider 5 and extends out of the corresponding elongated through slot 202. Of course, the arrangement of the distal end face may be a combination of the chassis 2 and the cover plate 3 in the above-described embodiment one.

When the number of the energy applying units 1 is four, the preset track may be four elongated through grooves 202 arranged at 90 ° on the chassis 2. The transverse slide 5 is connected with the intermediate transmission member 13, and the intermediate transmission member 13 is connected with the rotating member (i.e. the knob 8) through the rotating shaft 12, and can mutually rotate. The transverse slide 5 has a circular through slot for fastening the energy application unit 1. When the knob 8 is turned, the intermediate transmission member 13 rotates and moves, and the movement of the intermediate transmission member 13 rotates and moves the lateral slider 5, so that the energy applying unit 1 also moves because the energy applying unit 1 is fixed on the lateral slider 5, but the movement path of the energy applying unit 1 is limited by the needle track (the elongated through slot 202) on the chassis 2. When the energy application units 1 are moved, the interval between the energy application units 1 is changed, and thus the ablation area is changed. Also, since the movements of the energy application units 1 occur in the same plane and the energy application units 1 are initially parallel to each other, the execution ends of the respective energy application units 1 are always in the same plane.

Example III

Referring to fig. 16 and 17, the present embodiment also provides a multi-needle steep pulse ablation electrode device based on the first embodiment, in which the arrangement form of the driving part is adjusted, specifically as follows:

in this embodiment, the power input unit is a vertical power input mechanism, the power executing unit is a plurality of oblique connecting rods 15, and the connecting sliding unit is a transverse sliding block 5.

The input end of the vertical power input mechanism extends out of the handheld shell 11, and the output end of the vertical power input mechanism is respectively connected with the first ends of the inclined connecting rods 15 in a rotating and/or swinging mode and is used for driving the first ends of the inclined connecting rods 15 to vertically move. The second ends of the oblique connecting rods 15 are respectively connected with the corresponding transverse sliding blocks 5 in a rotating and/or swinging manner (if the preset track is a straight line, only the rotation needs to be satisfied).

As in the embodiment, the distal end surface of the hand-held housing 11 is a chassis 2, and the chassis 2 is provided with a plurality of elongated through grooves 202 for the energy application unit 1 to pass through, and the track of the elongated through grooves 202 is a preset track. The transverse slider 5 slides on the chassis 2, and the energy application unit 1 is clamped on the transverse slider 5 and extends out of the corresponding elongated through slot 202. Of course, the arrangement of the distal end face may be a combination of the chassis 2 and the cover plate 3 in the above-described embodiment one.

Further, to ensure stability of the diagonal link motion, the power execution unit further includes a support link 16, wherein a first end of the support link 16 is rotatably and/or swingably connected to the handheld housing 11, and a second end of the support link 16 is rotatably and/or swingably connected to a rod body of the diagonal link 15 (specifically, may be a midpoint or other position of the diagonal link 15).

Specifically, the vertical power input mechanism may include a rotating member, an adjusting screw 9, a connecting slider 14, and a vertical elastic member 7; the adjusting screw rod 9 is vertically arranged in the handheld shell 11, the adjusting screw rod 9 is in threaded connection with the proximal end face of the handheld shell 11, the connecting slide block 14 is rotationally connected with the adjusting screw rod 9, and the connecting slide blocks 14 are respectively connected with the first ends of the inclined connecting rods 15; the rotating piece is fixed at one end of the adjusting screw rod 9 and extends out of the handheld shell 11; two ends of the vertical elastic piece 7 are respectively connected with the handheld shell 11 and the connecting sliding block 14.

When the number of the energy applying units 1 is four, the preset track may be four elongated through grooves 202 arranged at 90 ° on the chassis 2. The centre of the chassis 2 may be provided with a threaded cylinder for movement of the adjusting screw 9 on the rotating member (knob 8). The transverse slider 5 has a circular through-hole for fixing the energy application unit 1. The transverse slide block 5 is connected with the oblique connecting rod 15, the oblique connecting rod 15 is connected with the supporting connecting rod 16 and the oblique connecting rod 15 is connected with the connecting slide block 14 through piston pins, and the transverse slide block and the oblique connecting rod 15 can mutually rotate. The bottom center of the knob 8 is provided with the adjusting screw rod 9 which is in threaded fit with the chassis 2. When the knob 8 is turned, the knob 8 moves downward, so that the connecting slider 14 moves downward, the movement of the connecting slider 14 drives the rotation of the diagonal connecting rod 15 and the supporting connecting rod 16, and the rotation of the diagonal connecting rod 15 moves the lateral slider 5, so that the energy applying unit 1 moves. When the energy application units 1 are moved, the interval between the energy application units 1 is changed, and thus the ablation area is changed. Also, since the movements of the energy application units 1 occur in the same plane and the energy application units 1 are initially parallel to each other, the execution ends of the respective energy application units 1 are always in the same plane.

Example IV

This embodiment provides a method for performing ablation of tumor tissue using a multi-needle steep pulse ablation electrode assembly based on the first to third embodiments described above, comprising:

first, providing a multi-needle steep pulse ablation electrode device: it further includes a hand-held housing 11, a plurality of energy applying units 1, and a driving section. The connection ends of the plurality of energy application units 1 are configured to be inserted into and slidingly connected to the distal end surface of the handheld housing 11 along a preset track, and the execution ends of the plurality of energy application units 1 are located on the same plane and cooperate to form an energy application execution area. The driving part is arranged in the handheld shell 11, the power input end of the driving part extends out of the handheld shell 11, and the power output end of the driving part is respectively connected with the plurality of energy applying units 1. The driving part is configured such that the power input end receives an external power input and outputs a driving force from the power output end to drive the plurality of energy applying units 1 to slide along their corresponding preset trajectories, respectively.

In the second step, the driving part is configured to obtain an energy application execution area matching with a preset energy application area of the corresponding tumor tissue by rotating the knob 8 to drive each metal puncture needle to slide along its preset track.

Third, the multi-needle steep pulse ablation electrode assembly is configured such that each energy application unit 1 delivers or punctures to a target location corresponding to the target tissue.

Each energy application unit 1 is configured to deliver energy to a target tissue.

The method of the present embodiment is applicable, among other things, to in vitro experiments using multi-needle steep pulse ablation electrode assemblies to detect the accuracy of the energy application execution area formed by the assembly.

Example five

The present embodiment provides a radiofrequency ablation device, which defines a region to which energy is required to be applied to a target tissue as a preset radiofrequency ablation region, and includes a handheld housing 11, a plurality of energy application units 1, and a driving portion.

The connection ends of the energy application units 1 are configured to be inserted into and slidingly connected to the distal end surface of the handheld housing 11 along a preset track, and the execution ends of the energy application units 1 are located on the same plane and cooperate to form a radio frequency ablation execution area.

The driving part is arranged in the handheld shell 11, the power input end of the driving part extends out of the handheld shell 11, and the power output end of the driving part is respectively connected with the plurality of energy applying units 1. The driving part is configured to receive external power input through the power input end, and the power output end outputs driving force to drive the plurality of energy application units 1 to slide along preset tracks corresponding to the energy application units 1 respectively so as to adjust the radio frequency ablation execution area to be matched with the preset radio frequency ablation area.

In this embodiment, the plurality of energy applying units 1 are configured to be inserted into and slidingly connected to the distal end surface of the handheld housing 11 along a preset track, and a driving portion is disposed in the handheld housing 11, and each energy applying unit 1 is driven by the driving portion to slide on the distal end surface of the handheld housing 11 along the preset track, so that the distance between the energy applying units 1 and the area of the radio frequency ablation execution area formed by the matching of the execution ends of the energy applying units 1 are adjusted to adapt to the preset radio frequency ablation area of the target tumor to which energy needs to be applied, and the problem that the distance between the needles and the ablation area are difficult to be accurately controlled in the existing steep pulse ablation electrode is solved. After the device is adjusted to fit the target tumor, the execution end of the energy application unit 1 can reach the target tumor to apply energy in a conveying or penetrating mode, so that radio frequency ablation can be performed on the target tumor in the radio frequency ablation execution area.

The present embodiment differs from the first embodiment in that the energy application unit 1 of the present embodiment is for radiofrequency ablation, and may be specifically a radiofrequency ablation needle. When the radio frequency current in the radio frequency ablation needle flows through human tissue, the water molecules with polarity in the tissue move at high speed due to the rapid change of the electromagnetic field, heat is generated (i.e. internal heating effect), so that the water inside and outside the cell is evaporated, dried, and condensed and falls off to cause aseptic necrosis, thereby achieving the aim of treatment.

Example six

The embodiment provides a tumor ablation device, which comprises a carrier carrying a plurality of treatment units and a driving part,

the connecting ends of the treatment units are inserted into and connected to the distal end face of the carrier in a sliding mode along a preset track, and the executing ends of the treatment units are located on the same plane and form an energy application executing area in a matched mode. And the driving part is arranged in the carrier, and the power output end of the driving part is respectively connected with each treatment unit. The driving part is configured to drive each treatment unit to slide along the corresponding preset track so as to adjust the energy application execution area to be matched with the preset tumor ablation area.

Example seven

The present embodiment provides a medical minimally invasive system based on the first to fourth embodiments described above. The medical minimally invasive system configures the plurality of energy application units 1 to be inserted into and slidingly connected to the distal end surface of the handheld shell 11 along the preset track, a driving part is arranged in the handheld shell 11, and the driving part drives each energy application unit 1 to slide on the distal end surface of the handheld shell 11 along the preset track, so that the distance between the energy application units 1 and the area of an energy application execution area formed by matching the execution ends of the energy application units 1 are adjusted to adapt to the preset energy application area of the energy required to be applied by a target tumor, and the problem that the distance between needles and the ablation area are difficult to accurately control in the conventional steep pulse ablation electrode is solved. After the energy application unit is adjusted to fit the target tumor, the execution end of the energy application unit 1 can reach the target tumor in a conveying or penetrating mode to apply energy so as to ablate the target tumor in an energy application execution area.

Application example

The present application example is exemplified on the basis of the above embodiments one to four: firstly, the space between the metal puncture needles and the ablation area are matched to corresponding tumor targets by rotating the knob 8, the metal puncture needles are inserted into the lesion sites of a patient in a mode of being held by the hand-held part, then the high-voltage pulse power supply is started, the high-frequency high-voltage pulse current output by the high-voltage pulse power supply is led into the lesion sites of the patient through one or more metal puncture needles, the rest metal puncture needles serve as loop electrodes to lead the high-frequency high-voltage pulse current into the input ends of the high-voltage pulse power supply, when the high-frequency high-voltage pulse current passes through the lesion cells of the patient, the high-frequency high-voltage pulse current can damage the cell membranes of the lesion cells, so that the lesion cells are killed, and the high-frequency high-voltage pulse current only passes through the lesion sites locally and cannot damage healthy cells outside the lesion tissues due to the fact that the metal puncture needles serve as loop electrodes.

The embodiments of the present invention have been described in detail with reference to the drawings, but the present invention is not limited to the above embodiments. Even if various changes are made to the present invention, it is within the scope of the appended claims and their equivalents to fall within the scope of the invention.

Claims

1. A multi-needle steep pulse ablation electrode assembly defining a region of desired energy application to a target tissue as a preset energy application region, comprising:

a hand-held housing;

2. The multi-needle steep pulse ablation electrode device according to claim 1, wherein the preset trajectories of a plurality of the energy application units are configured to converge toward and/or diverge outwardly from a center of the hand-held housing distal face, and the shape of the energy application execution area is configured as a regular polygon.

3. The multi-needle steep pulse ablation electrode device of claim 1, wherein a direction perpendicular to the distal surface of the hand-held housing is defined as vertical and a direction parallel to the distal surface of the hand-held housing is defined as lateral;

4. The multi-needle steep pulse ablation electrode device according to claim 3, wherein the power input unit is a vertical power input mechanism, the power execution unit comprises a vertical slide block and an elastic force supply unit, and the connecting slide unit is a horizontal slide block provided with a guiding inclined plane;

5. The multi-needle steep pulse ablation electrode device according to claim 4, wherein the vertical power input mechanism comprises a rotator, an adjusting screw and a fixing nut;

The fixing nut is fixed on the vertical sliding block; the adjusting screw is vertically arranged and is in threaded connection with the fixing nut; the rotating piece is fixed at one end of the adjusting screw rod and extends out of the handheld shell;

the rotating piece comprises a knob and a vertical elastic piece; the bottom end of the knob is provided with an extension boss extending outwards and used for being abutted to the proximal end face of the handheld shell; two ends of the vertical elastic piece are respectively connected with the extension boss and the vertical sliding block;

the elastic force supply unit is an annular compression spring;

6. The multi-needle steep pulse ablation electrode device according to claim 4, wherein the vertical slider comprises a slider body, and a vertical guiding structure and a plurality of oblique guiding structures arranged on the slider body;

The upper end of the transverse sliding block is provided with a protruding structure, and two sides of the protruding structure are respectively provided with an inclined step surface matched with the guide inclined surface;

the transverse sliding block is internally provided with embedded through grooves which are vertically arranged and extend to the protruding structures.

7. The multi-needle steep pulse ablation electrode device according to claim 4, wherein an extension sliding table extending towards at least one side of the preset track is arranged at the lower end of the transverse sliding block;

the far end face of the handheld shell is of a far end bottom plate structure, and the far end bottom plate structure comprises a chassis and a cover plate; the chassis is respectively provided with a guide groove corresponding to each preset track, the width of the guide groove is matched with the whole size of the extension sliding table; the bottom surface of the guide groove is provided with a strip-shaped through groove for the energy applying unit to pass through; the cover plate is covered on the chassis and is provided with guide openings corresponding to the guide grooves one by one, the width of the guide openings is matched with that of the transverse sliding blocks, and the chassis and the cover plate are respectively provided with an extending opening for enabling the vertical sliding blocks to extend in.

8. The multi-needle steep pulse ablation electrode device according to claim 3, wherein the power input unit is a rotating member, the power executing unit is a plurality of intermediate transmission members, and the connecting sliding unit is a transverse sliding block;

9. The multi-needle steep pulse ablation electrode device according to claim 3, wherein the power input unit is a vertical power input mechanism, the power execution unit is a plurality of oblique connecting rods, and the connecting sliding unit is a transverse sliding block;

10. The multi-needle steep pulse ablation electrode device according to claim 9, wherein the power execution unit further comprises a support link, a first end of the support link being rotatably and/or swingably connected to the hand-held housing, and a second end of the support link being rotatably and/or swingably connected to a shaft of the diagonal link.

11. The multi-needle steep pulse ablation electrode device according to claim 10, wherein the vertical power input mechanism comprises a rotating member, an adjusting screw, a connecting slider and a vertical elastic member;

12. The multi-needle steep pulse ablation electrode device according to claim 1, wherein the energy application unit is a metal puncture needle, and the number of the energy application units is three or four or five.

13. A method of ablating an electrode assembly using a multi-needle steep pulse, comprising:

the driving part is configured to receive an external power input to drive each of the energy application units to slide along a preset track thereof, and to obtain the energy application execution area matched with a preset energy application area.

14. A radio frequency ablation device defining a region of desired energy application to target tissue as a preset radio frequency ablation region, comprising:

a hand-held housing;

the connecting ends of the energy application units are inserted into and connected to the far-end surface of the handheld shell in a sliding mode along a preset track, and the executing ends of the energy application units are located on the same plane and form a radio frequency ablation executing area in a matching mode;

the driving part is configured to receive external power input from the power input end, and the power output end outputs driving force to drive the energy applying units to slide along the preset tracks corresponding to the energy applying units respectively so as to adjust the radio frequency ablation execution area to be matched with the preset radio frequency ablation area.

15. A tumor ablation device, comprising:

16. A minimally invasive medical system comprising a multi-needle steep pulse ablation electrode assembly according to any of claims 1 to 12.