CN116421808B - Plasma adsorption and filtration device for asthma treatment and filtration method thereof - Google Patents

Plasma adsorption and filtration device for asthma treatment and filtration method thereof Download PDF

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Publication number
CN116421808B
CN116421808B CN202310223102.9A CN202310223102A CN116421808B CN 116421808 B CN116421808 B CN 116421808B CN 202310223102 A CN202310223102 A CN 202310223102A CN 116421808 B CN116421808 B CN 116421808B
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plasma
filter element
pipe
filter
asthma
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CN116421808A (en
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陈杰
徐曦
王蕊
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Jiangsu Qirui Biotechnology Co ltd
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Jiangsu Qirui Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3627Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633Blood component filters, e.g. leukocyte filters
    • A61M1/3635Constructional details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687Chemical treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • A61M2202/0413Blood
    • A61M2202/0415Plasma
    • A61M2202/0423Serum; Human serous fluid, i.e. plasma without fibrinogen
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/20Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters

Abstract

The invention discloses a plasma adsorption and filtration device for asthma treatment and a filtration method thereof, and relates to the technical field of plasma adsorption and filtration. The invention can adsorb inflammatory factors such as IL-8 in blood plasma through the first filter element component, can reduce the inflammatory factors to participate in airway inflammatory reaction of asthma, quickly and effectively improve symptoms of asthma patients, shorten treatment time, change the traditional treatment scheme by means of hormone medication, reduce hormone medication of the asthma patients, reduce side effects, simultaneously reduce pain of the patients, and adopt a pure physical treatment mode, thereby not only being safe and reliable, but also providing a new clinical treatment scheme, and being capable of effectively avoiding infection hidden trouble caused by inputting blood plasma of other people without supplementing blood plasma during treatment, and effectively preventing and treating.

Description

Plasma adsorption and filtration device for asthma treatment and filtration method thereof
Technical Field
The invention relates to the technical field of plasma adsorption filtration, in particular to a plasma adsorption filtration device for asthma treatment and a filtration method thereof.
Background
Asthma is a chronic inflammatory disease of the respiratory tract caused by genetic constitution plus external environmental stimuli, which has fundamentally different nature from that of common inflammation caused by bacterial or viral infection; frequent wheezing symptoms, obvious shortness of breath, accelerated heart rate and limited speaking activity; can cause great sweat dribbling, cyanosis, extreme anxiety, sleepiness and conscious disturbance, and the disease is dangerous and needs emergency rescue; the main inducing factors are as follows: bronchi have obstruction, severe dehydration and extreme patient failure.
The prior Chinese patent publication No. CN111450362A proposes a treatment device and a system for asthmatic patients, and in the scheme of the invention, the treatment device comprises a liquid inlet bottle group, an atomization generator and an atomization liquid outlet pipe, and although the pulse jet type liquid outlet can be realized in the scheme of the invention, the action range of medicines in atomization administration is improved, but only the atomized hormone medicines can be inhaled to control inflammatory reaction, and other modes can not be provided for reducing side effects brought by the use of hormones by patients, while in the traditional plasma replacement technology, plasma of patients is only separated and discarded, and plasma replacement is supplemented, so that the hidden danger that blood coagulation factors are consumed exists, and the risk of losing plasma per se during treatment is avoided.
Disclosure of Invention
In order to achieve the above purpose, the invention is realized by the following technical scheme: a plasma adsorption filtration device for asthma treatment, comprising a plasma adsorber;
the top of the upper shell is fixedly connected with an exhaust port at a position close to the edge;
a lower housing;
a feeding tube assembly for delivering whole blood into the housing;
and a filter cartridge comprising a first filter cartridge component and a second filter cartridge component, the first filter cartridge component being located above the second filter cartridge component;
the upper shell is detachably arranged at the top of the plasma absorber, the lower shell is embedded and arranged at the bottom of the plasma absorber, an accommodating space is formed between the bottom of the plasma absorber and the lower shell, the filter element is positioned and installed in the fixed cover.
Preferably, the tube inlet assembly comprises a blood inlet tube which is perpendicular to the top end of the upper shell, the bent tube part at the tail end of the blood inlet tube is fixedly connected with a lower guide tube, the inlet of the transverse tube part of the lower guide tube is fixedly connected with the bent tube part at the tail end of the blood inlet tube, the lower guide tube is communicated with the inner side of the blood inlet tube, and the bent tube part at the tail end of the lower guide tube is fixedly connected with the middle part of the top end of the upper shell.
Preferably, the bent pipe part at the tail end of the blood inlet pipe is fixedly connected with a bulb and is used for plugging the bent pipe part at the tail end of the blood inlet pipe.
Preferably, a first deceleration part is arranged at a position where the bent pipe part of the blood inlet pipe coincides with the transverse pipe part of the lower guide pipe, and a second deceleration part is arranged at the inner side of the bent pipe part of the lower guide pipe.
Preferably, the first filter element component comprises an overhead filter plate which is embedded and installed at the uppermost part of the inner side of the fixed cover, at least nine auxiliary filter plates are installed below the overhead filter plate in parallel, and the overhead filter plate and the auxiliary filter plates are mainly made of diatomite materials containing negative electrons, so that plasma is filtered layer by layer.
Preferably, the side of overhead filter plate is equilateral triangle and has laid three at least overhead cards, just the side of affiliated filter plate is equilateral triangle and has laid three at least subordinate cards, and subordinate cards on two adjacent subordinate filter plates dislocation 12 at least, and overhead cards and a plurality of subordinate cards constitute complete ring wall jointly, and first filter element assembly passes through the inboard of ring wall gomphosis installation at the fixed cover.
Preferably, the second filter element component consists of a microporous filter membrane with the aperture of 0.2-0.25 micrometers, the total number of layers of the second filter element component is 1-3, the main material is made of nylon, and the second filter element component is embedded and installed on the inner side of the fixed cover through the annular wall of the first filter element component to block bacteria from passing through.
Preferably, the bottom wall surface of the plasma absorber is provided with a slot, the inner wall of the plasma absorber is fixedly connected with a dome cover, the upper wall of the lower shell is fixedly connected with a wall ring, the plasma absorber is covered with the lower shell through the cooperation of the slot and the wall ring, and the dome cover is embedded and installed with the upper port of the fixed cover through the cooperation of the plasma absorber and the lower shell.
Preferably, the inner wall surface bottom fixedly connected with drainage fill of lower casing, just the limit rail has been seted up to the top avris of drainage fill, and the fixed cover passes through the limit rail block on the drainage fill, the collection mouth has been seted up at the middle part of drainage fill, and the bottom middle part fixedly connected with of lower casing is with the communicating play blood vessel of collection mouth.
A filtration method of a plasma adsorption filtration device for asthma treatment, comprising the steps of:
step one: firstly, placing a second filter element assembly into a fixed cover, then placing a first filter element assembly into the fixed cover, placing the first filter element assembly at the top of the second filter element assembly, placing the fixed cover into a lower shell, clamping a limit rail on the lower shell and a drainage hopper, covering a plasma adsorber at the top of the lower shell, and fixing the plasma adsorber and the lower shell;
step two: introducing the plasma of a patient into the filtering device from a blood inlet tube, leading the plasma of the patient into the filtering device through a first decelerating part and a second decelerating part at the inner sides of the blood inlet tube and a lower guiding tube, exhausting through an exhaust port in an upper shell, and then entering a first filter element component through a plasma absorber, wherein inflammatory factors such as IL-8 in the plasma can be adsorbed through an overhead filter plate and an auxiliary filter plate which are mainly composed of diatomite materials containing negative electrons;
step three: and the plasma filtered by the first filter element component enters the second filter element component, the micro-pore filter membrane filters macromolecular substances in the plasma of the patient at the moment, the filtered plasma of the patient completes the purification process, and the purified plasma of the patient is conveyed back to the patient.
The invention provides a plasma adsorption and filtration device for asthma treatment and a filtration method thereof. The beneficial effects are as follows:
1. according to the plasma adsorption and filtration device for asthma treatment and the filtration method thereof, inflammatory factors such as IL-8 in plasma and the like are adsorbed by the first filter element component, so that the inflammatory factors can be reduced to participate in airway inflammatory reaction of asthma, symptoms of asthma patients can be quickly and effectively improved, treatment time is shortened, a traditional treatment scheme depending on hormone administration is changed, the hormone administration of the asthma patients is reduced, side effects are reduced, and meanwhile pain of the patients is reduced.
2. According to the plasma adsorption and filtration device for asthma treatment and the filtration method thereof, the first filter element component is used for filtering and intercepting inflammatory factors such as IL-8 in plasma of a patient and the second filter element component is used for blocking bacteria, and the pure physical treatment mode is adopted, so that the device is safe and reliable, a new clinical treatment scheme is provided, and the plasma of other people is not required to be supplemented during treatment, so that the hidden infection trouble caused by inputting the plasma of other people can be effectively avoided.
3. According to the plasma adsorption and filtration device and the filtration method for asthma treatment, inflammatory factors such as IL-8 in the plasma of a patient can be filtered and intercepted, so that the treatment can be carried out before the asthma of the patient, and the effective prevention and treatment can be carried out before the asthma of the patient.
Drawings
FIG. 1 is a schematic view showing the external structure of a plasma adsorption filtration device for asthma treatment according to the present invention;
FIG. 2 is a schematic diagram showing the internal structure of a plasma adsorption filtration device for asthma treatment according to the present invention;
FIG. 3 is an exploded view showing the internal structure of a plasma adsorption filtration device for asthma treatment according to the present invention;
FIG. 4 is an enlarged view of FIG. 3 at A;
FIG. 5 is a schematic view of the structure of the lower housing of the present invention;
FIG. 6 is a schematic view of the tube assembly of the present invention;
FIG. 7 is a schematic illustration of the construction of a first cartridge assembly of the present invention;
fig. 8 is a flow chart of a filtration method of a plasma adsorption filtration device for asthma treatment of the present invention.
In the figure: 1. an upper housing; 2. a lower housing; 3. a tube inlet assembly; 301. entering a blood vessel; 302. ball head; 303. a lower guide tube; 304. a first deceleration section; 305. a second deceleration section; 4. an exhaust port; 5. a first filter element assembly; 501. a filter plate is arranged on the top; 502. an auxiliary filter plate; 503. a card is arranged on the top; 504. a slave card; 6. a fixed cover; 7. a second filter element assembly; 8. a slot; 9. a dome cover; 10. a wall ring; 11. a drainage bucket; 12. a limit rail; 13. a collection port; 14. exiting a blood vessel; 15. a plasma adsorber.
Detailed Description
The invention will be described in further detail with reference to the drawings and the detailed description. The embodiments of the invention have been presented for purposes of illustration and description, and are not intended to be exhaustive or limited to the invention in the form disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, and to enable others of ordinary skill in the art to understand the invention for various embodiments with various modifications as are suited to the particular use contemplated.
In this embodiment, as shown in fig. 1 to 8, the present invention provides a technical solution, that is, treatment is completed by integrating a blood component separator, which is a first solution: a plasma adsorption filtration device for asthma treatment, comprising a plasma adsorber 15; the upper shell 1, the top of the upper shell 1 is fixedly connected with an exhaust port 4 at a position close to the edge for exhausting; a lower case 2; an intake tube assembly 3 for delivering whole blood into the housing; the bent pipe part at the tail end of the blood inlet tube 301 is fixedly connected with a lower guide tube 303, the inlet of the transverse tube part of the lower guide tube 303 is fixedly connected with the bent pipe part at the tail end of the blood inlet tube 301, the lower guide tube 303 is communicated with the inner side of the blood inlet tube 301, the bent pipe part at the tail end of the lower guide tube 303 is fixedly connected with the middle part of the top end of the upper shell 1, the bent pipe part at the tail end of the blood inlet tube 301 is fixedly connected with a ball head 302, a first deceleration part 304 is arranged at the position where the bent pipe part of the blood inlet tube 301 and the transverse tube part of the lower guide tube 303 coincide, and a second deceleration part 305 is arranged at the inner side of the bent pipe part of the lower guide tube 303;
a filter cartridge comprising a first filter cartridge assembly 5 and a second filter cartridge assembly 7, the first filter cartridge assembly 5 being located above the second filter cartridge assembly 7;
the upper shell 2 is detachably arranged at the top of the plasma absorber 15, the lower shell 2 is embedded and arranged at the bottom of the plasma absorber 15, an accommodating space is formed between the bottom of the plasma absorber 15 and the lower shell 2, the fixed cover 6 is embedded and arranged in the accommodating space, the pipe inlet component 3 is fixedly connected with the middle part of the top end of the upper shell 1, and the filter element is positioned and arranged in the fixed cover 6.
At least nine auxiliary filter plates 502 are arranged in parallel below the top filter plate 501, and the top filter plate 501 and the auxiliary filter plates 502 are made of diatomite materials containing negative electrons; the auxiliary cards 504 on the two adjacent auxiliary filter plates 502 are staggered at least by 12 degrees, the top card 503 and the auxiliary cards 504 form a complete circular wall together, and the first filter element component 5 is embedded and installed on the inner side of the fixed cover 6 through the circular wall; the top card 503 and the plurality of subordinate cards 504 form a complete circular wall together, the second filter element assembly 7 is integrally and limitedly arranged between the first filter element assembly 5 and the fixed cover 6, so that the plasma filtered and adsorbed by the first filter element assembly 5 directly enters the second filter element assembly 7, the inflow of the plasma to other spaces or gaps is avoided, the invalid branches and the flow of the plasma are reduced, the flow path of the plasma is shortened, the tight connection of the second filter element assembly 7 to the plasma filtration treatment is realized, and the bacterial passing is quickly and effectively blocked;
the second filter element component 7 consists of a microporous filter membrane with the aperture of 0.2-0.25 micrometers, the total number of layers of the second filter element component 7 is 1-3, and the main material is made of nylon.
When in use, the first filter element component 5 mainly composed of diatomite material containing negative electrons can effectively adsorb inflammatory factors such as IL-8 in blood plasma by utilizing the peculiar specific adsorption property and the negative electrons contained in the first filter element component, reduce the participation of the inflammatory factors in airway inflammatory reaction of asthma, and can quickly and effectively improve symptoms of asthma patients; the adsorption effect of inflammatory factors can be improved by the filter element which carries out organic physical surface modification on diatomite materials;
the pore diameter of the micro-pore filtration membrane material of the second filter element assembly 7 is between 0.2 and 0.25 microns, and under the condition that bacteria are larger than 0.5 microns, macromolecular substances in plasma of a patient can pass through the pore diameter, so that the passing of the bacteria can be blocked under the condition that the patient is not influenced, and the safety of treatment is improved; for the current non-specific treatment method of the asthma without hepatorenal toxicity, long-term standardized treatment is required to be adhered to control the asthma, so that the recurrence is reduced, the illness state of a patient can be rapidly and effectively controlled, and the quality of life is improved;
through the first decelerating part 304 and the second decelerating part 305 arranged at the inner sides of the blood inlet pipe 301 and the lower guiding pipe 303, when the blood plasma is input to the first filter element assembly 5, the flow velocity of the blood plasma can be buffered twice, so that the direct impact of the blood plasma to the top-mounted filter plate 501 is weakened, IL-8 inflammatory factors in the blood plasma are prevented, the holes of the top-mounted filter plate 501 positioned at the uppermost part are directly blocked, the service life of the top-mounted filter plate 501 is prolonged, and the tops of the rest auxiliary filter plates 502 can fully play a role in the process of adsorbing and filtering the blood plasma;
secondly, by the plasma buffered by the first decelerating section 304 and the second decelerating section 305, after being led into the inner side of the dome cover 9 via the downdraft tube 303, the vertical downward flow speed of the plasma is slowed down, the initial effective contact area between the plasma and the top filter plate 501 is enlarged, and the plasma is exclusively led onto the first filter element assembly 5 mounted above the fixed cover 6 by the dome cover 9, the overall effective contact area between the first filter element assembly 5 and the plasma can be enlarged; through the operation, under the buffer guidance of the plasma by the inlet pipe component 3, the effective filtering area of the plasma by the first filter element component 5 is increased in an auxiliary way, the traditional vertical downward flow guiding type plasma guiding mode is changed, and the traditional direct current pipe type guiding not only ensures that the initial inflow velocity of the plasma is high, but also ensures that the initial effective contact area of the plasma and the filter element is small, thus the filtering effect of the filter element on the plasma is not fully exerted;
meanwhile, by means of the mutual matching between the drainage hopper 11, the collection port 13 and the blood tube 14, the filtered and adsorbed blood plasma can be gathered and guided rapidly and returned to the patient, so that the blood plasma return time is shortened, and the discomfort caused by the filtration of the blood plasma of the patient is reduced;
and utilize the upper port of vault 9 bottom insertion fixed cover 6, eliminate the hidden danger that first filter core subassembly 5 and second filter core subassembly 7 are linked together with external air through gas vent 4, isolate vault 9 promptly, fixed cover 6, drainage fill 11 and the unnecessary space between plasma adsorber 15, utilize the drainage space that plasma adsorber 15, lower casing 2 and dome 9, fixed cover 6, drainage fill 11 constitute jointly, provide dual isolation measure for the appearance of unnecessary bubble in the plasma, guarantee that plasma can fill fast in the drainage space that dome 9, fixed cover 6, drainage fill 11 formed, when avoiding unnecessary bubble to produce, can release the bubble that probably exists from the gap of ring wall under the delivery pressure of plasma, then discharge by gas vent 4, guarantee that this filter equipment filters the smooth of plasma.
The treatment process comprises the following steps: blood is collected and punctured at a vein of a patient by utilizing a blood taking needle, blood of the patient is led out, whole blood of the patient is separated into plasma and blood cells by a plasma separating device, the blood cells are returned into the patient by equipment, the plasma is adsorbed, filtered and purified by an asthma treatment filter, and the purified plasma is returned into the patient:
among them, there are two other treatment regimens that differ in the way plasma is separated by the treatment device:
the second scheme is that the centrifugal plasma single-sampling machine and the peristaltic pump are combined for treatment; wherein, the centrifugal plasma single-sampling machine is used for separating and transporting blood cells from plasma; the peristaltic pump is used for transporting blood plasma and measuring pressure of the filter;
a third scheme is that the column type plasma separator is combined with the continuous blood purifying equipment for treatment; wherein the column plasma separator is used for separating plasma; and the continuous blood purification device is used for transporting whole blood, blood cells, plasma and filter for pressure measurement.
It will be apparent that the described embodiments are only some, but not all, embodiments of the invention. All other embodiments, which can be made by those skilled in the art and which are included in the embodiments of the present invention without the inventive step, are intended to be within the scope of the present invention. Structures, devices and methods of operation not specifically described and illustrated herein, unless otherwise indicated and limited, are implemented according to conventional means in the art.

Claims (8)

1. A plasma adsorption filtration device for use in the treatment of asthma, comprising: a plasma adsorber (15); the upper shell (1), the top of the upper shell (1) is fixedly connected with an exhaust port (4) at a position close to the edge; a lower case (2); a pipe inlet assembly (3); the filter element comprises a first filter element component (5) and a second filter element component (7), and the first filter element component (5) is positioned above the second filter element component (7); the utility model discloses a plasma adsorber, including upper casing (1), lower casing (2), plasma adsorber (15), filter core, wherein, upper casing (1) is detachably installed at the top of plasma adsorber (15), lower casing (2) gomphosis is installed in the bottom of plasma adsorber (15), and has formed accommodation space between the bottom of plasma adsorber (15) and lower casing (2), fixed cover (6) are installed to the gomphosis in accommodation space, advance pipe assembly (3) fixed connection in the top middle part of upper casing (1), filter core location is installed in fixed cover (6), slot (8) have been seted up on plasma adsorber (15) diapire surface, and the inner wall fixedly connected with dome cover (9) of plasma adsorber (15), upper wall fixedly connected with wall ring (10) of lower casing (2), plasma adsorber (15) pass through slot (8) and wall ring (10) cooperation and lower casing (2) lid, wherein, dome cover (9) are installed through the cooperation of lower casing (2) and plasma adsorber (15) and the last port gomphosis of fixed cover (6).
2. The plasma adsorption filtration device for asthma treatment according to claim 1, wherein: the pipe feeding assembly (3) comprises a blood feeding pipe (301) which is perpendicular to the top end of the upper shell (1), a lower guide pipe (303) is fixedly connected to the bent pipe part at the tail end of the blood feeding pipe (301), the inlet of the transverse pipe part of the lower guide pipe (303) is fixedly connected with the bent pipe part at the tail end of the blood feeding pipe (301), the lower guide pipe (303) is communicated with the inner side of the blood feeding pipe (301), and the bent pipe part at the tail end of the lower guide pipe (303) is fixedly connected to the middle part of the top end of the upper shell (1).
3. The plasma adsorption filtration device for asthma treatment according to claim 2, wherein: the bent pipe part at the tail end of the blood inlet pipe (301) is fixedly connected with a bulb (302).
4. A plasmafilter for use in the treatment of asthma according to claim 3, wherein: a first deceleration part (304) is arranged at a position where the bent pipe part of the blood inlet pipe (301) is overlapped with the transverse pipe part of the lower guide pipe (303), and a second deceleration part (305) is arranged at the inner side of the bent pipe part of the lower guide pipe (303).
5. The plasma adsorption filtration device for asthma treatment according to claim 1, wherein: the first filter element assembly (5) comprises an overhead filter plate (501) which is embedded and installed at the uppermost part of the inner side of the fixed cover (6), at least nine auxiliary filter plates (502) are installed below the overhead filter plate (501) in parallel, and the overhead filter plate (501) and the auxiliary filter plates (502) are mainly made of diatomite materials containing negative electrons.
6. The plasma adsorption filtration device for asthma treatment according to claim 5, wherein: the side of overhead filter plate (501) is equilateral triangle and has laid at least three overhead card (503), just the side of subordinate filter plate (502) is equilateral triangle and has laid at least three subordinate card (504), subordinate card (504) on two adjacent subordinate filter plates (502) dislocation 12 at least, and overhead card (503) and a plurality of subordinate card (504) constitute complete ring wall jointly, and first filter core subassembly (5) are installed in the inboard of fixed cover (6) through ring wall gomphosis.
7. The plasma adsorption filtration device for asthma treatment according to claim 6, wherein: the second filter element component (7) consists of a microporous filter membrane with the aperture of 0.2-0.25 micrometers, the total number of layers of the second filter element component (7) is 1-3, the main material is made of nylon, and the second filter element component (7) is embedded and installed on the inner side of the fixed cover (6) through the annular wall of the first filter element component (5).
8. The plasma adsorption filtration device for asthma treatment according to claim 1, wherein: the drainage bucket is characterized in that the bottom of the inner wall surface of the lower shell (2) is fixedly connected with a drainage bucket (11), a limit rail (12) is arranged on the side of the top of the drainage bucket (11), the fixed cover (6) is clamped on the drainage bucket (11) through the limit rail (12), a collecting port (13) is arranged in the middle of the drainage bucket (11), and a bleeding pipe (14) communicated with the collecting port (13) is fixedly connected to the middle of the bottom of the lower shell (2).
CN202310223102.9A 2023-03-09 2023-03-09 Plasma adsorption and filtration device for asthma treatment and filtration method thereof Active CN116421808B (en)

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CN114949412A (en) * 2022-06-20 2022-08-30 王昌卿 Multipurpose blood purifier
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