CN116407339A

CN116407339A - Intraocular lens

Info

Publication number: CN116407339A
Application number: CN202111649297.0A
Authority: CN
Inventors: 甄彦杰
Original assignee: Abbott Beijing Medical Technology Co ltd
Current assignee: Abbott Beijing Medical Technology Co ltd
Priority date: 2021-12-30
Filing date: 2021-12-30
Publication date: 2023-07-11

Abstract

The intraocular lens of the present invention includes an optical portion having an optical axis, and haptics extending from the optical portion to the outer peripheral side, the haptics having a thickened portion having a thickness greater than a width. Because the loop has a thickening portion, the thickness of the thickening portion is larger than the width, the contact area between the loop and the human eye capsular bag can be increased, and the position stability of the intraocular lens in the human eye capsular bag is higher.

Description

Intraocular lens

Technical Field

The present invention relates to an intraocular lens.

Background

Intraocular lenses may be implanted in the human eye to treat cataracts. As patients have increased postoperative requirements, the human lens has developed a variety of different structural designs. Through different structural designs, the artificial lens brings more stable performance, so that the artificial lens can meet various requirements of patients.

Positional stability, such as centering stability, rotational stability, etc., is important after intraocular lens implantation. For example, an intraocular lens may cause 300 degrees of ametropia when displaced axially by 1mm at the location within the eye; alternatively, when the intraocular lens is optically decentered, tilted, the quality of the optical image is significantly affected.

For another example, when the axial direction of the Toric intraocular lens is rotated more than 5 ° from the axial position of the cornea of a human eye, the intraocular lens will affect the correction of astigmatism.

Therefore, it is very important to improve the positional stability of the intraocular lens.

Disclosure of Invention

In view of the above, the present invention provides an intraocular lens capable of improving positional stability after implantation.

The intraocular lens of the present invention includes an optical portion having an optical axis, and haptics extending from the optical portion to the outer peripheral side, the haptics having a thickened portion having a thickness greater than a width.

It will be appreciated that the thickness of the haptics is the dimension in the direction of the optical axis and the width is the dimension in a direction generally perpendicular to the direction of extension. In addition, the extending direction of the loop may be coincident with the radial direction of the optic or may be at an angle to the radial direction of the optic.

Because the loop has a thickening portion, the thickness of the thickening portion is larger than the width, the contact area between the loop and the human eye capsular bag can be increased, and the position stability of the intraocular lens in the human eye capsular bag is higher.

Optionally, the thickening extends over the entirety of the haptics.

Optionally, the haptic has a plurality of said thickenings with spaces therebetween.

Alternatively, the thickness of the haptics is constant in the direction of extension.

Optionally, the thickness of the haptics varies in the direction of extension.

Alternatively, the width of the haptics is constant in the direction of extension.

Optionally, the width of the haptics varies in the direction of extension.

Alternatively, the thickness of the haptics becomes progressively greater toward the outer peripheral side.

Optionally, the haptics have a root proximal to the optic and a distal portion distal from the optic, the distal portion having the thickening.

Optionally, the haptics have a root portion adjacent the optic, a distal end portion distal from the optic and a central portion connected between the root portion and the distal end portion, the ratio of thickness to width of the haptics at the root portion being less than the ratio of thickness to width at the distal end portion.

Optionally, the haptic thickness to width ratio at the central portion is between the root thickness to width ratio and the distal portion thickness to width ratio.

Optionally, the thickness of the thickening is 0.1-2.5 mm, 0.4-1.5 mm or 0.5-1 mm.

Optionally, the ratio of the thickness to the width of the thickening is (1.01-5): 1, (1.1-2): 1 or (1.3-1.8): 1.

Optionally, the thickness of the loop is larger as it approaches the periphery, the ratio of the thickness to the width of the region with the largest thickness is (5:1-1.01:1), (3:1) to (1.1:1) or (2:1) to (1.2:1), and the ratio of the thickness to the width of the region with the smallest thickness is (3:1) to (1.01:1), (2:1) to (1.1:1) or (1.6:1) to (1.2:1).

Optionally, the thickness of the haptic is smaller as it is closer to the outer periphery or farther from the optical portion along the extending direction, the ratio of the thickness to the width of the region of maximum thickness is (5:1-1.01:1), (3:1) to (1.1:1), or (2:1) to (1.2:1), and the ratio of the thickness to the width of the region of minimum thickness is (3:1) to (1.01:1), (2:1) to (1.1:1), or (1.6:1) to (1.2:1).

Optionally, the ratio of thickness to width of the haptics at different regions satisfies the following relationship:

haptic-shaped length region	Thickness to width ratio
		5～8	1.1:1～1.3:1
8～11	1.3:1～1.5:1
		11～13.5	1.5:1～1.8:1

The "haptic length" refers to a length calculated from a junction of the haptic and the optical portion along an extending direction of the haptic. The haptics may extend in a direction coincident with the radial direction or may be angled with respect to the radial direction, i.e. inclined with respect to the radial direction. In this application, the haptics may extend along straight lines, along rounded curves, or some portions thereof may extend along straight lines and other portions may extend along rounded curves. The meaning of the curve includes a rounded curve and a curve formed by combining a straight line and a rounded curve.

By adopting the structure, the thickness and the width of the loop are close to each other, the ratio (ratio) of the thickness to the width of the loop is small, and the loop can be ensured to have larger supporting force in the radial direction; the proportion of the thickness and the width of the loop at the middle part is moderate, and the compression stress is released; the haptic has a maximum thickness at the distal end and a smaller width dimension in a larger ratio, thus maximizing the contact area of the haptic edge with the human eye capsular bag.

Drawings

FIG. 1a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 1b is a schematic side view of the intraocular lens;

FIG. 2a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 2b is a schematic side view of the intraocular lens;

FIG. 3a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 3b is a schematic side view of the intraocular lens;

FIG. 4a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 4b is a schematic side view of the intraocular lens;

FIG. 5a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 5b is a schematic side view of the intraocular lens;

FIG. 6a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 6b is a schematic side view of the intraocular lens;

FIG. 7a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 7b is a schematic side view of the intraocular lens;

FIG. 8a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 8b is a schematic side view of the intraocular lens;

FIG. 9a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 9b is a schematic side view of the intraocular lens;

FIG. 10a is a schematic front view of an intraocular lens according to one embodiment of the present invention;

FIG. 10b is a schematic side view of the intraocular lens;

FIG. 11a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 11b is a schematic side view of the intraocular lens;

FIG. 12a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 12b is a schematic side view of the intraocular lens;

FIG. 13a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 13b is a schematic side view of the intraocular lens;

FIG. 14a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 14b is a schematic side view of the intraocular lens;

FIG. 15a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 15b is a schematic side view of the intraocular lens;

FIG. 16a is a schematic front view of an intraocular lens according to an embodiment of the present invention;

FIG. 16b is a schematic side view of the intraocular lens;

FIGS. 17 a-17 f are schematic diagrams illustrating thickness variation of haptics according to some embodiments of the present invention.

Detailed Description

The following describes specific embodiments of the present invention in detail.

In particular embodiments of the present invention, an intraocular lens is provided comprising an optic and haptics, the materials including, but not limited to, polymethacrylates, silicone gels, hydrophilic acrylates, hydrophobic acrylates, and the like. The optical portion has an optical axis, and when the lens is implanted in a human eye, light is transmitted through the optical portion and is incident on the retina of the human eye, so that the human eye can normally perform a visual function, that is, the optical portion is an optically effective portion of the intraocular lens. The haptics extend from the optic to the peripheral side (also referred to as the radially outer side) and, in the state of implantation into the human eye, are positioned between the optic and human eye tissue (typically the capsular bag) to serve as supports for the optic.

It is understood that the outer-inner circumferential direction or radial direction refers to a direction substantially perpendicular to the optical axis of the optical portion.

The haptics have a thickening with a thickness greater than the width, or in the thickening, the thickness of the haptics is greater than the width.

It will be appreciated that the thickness of the haptics is the dimension generally along the optical axis of the optic and the width of the haptics is the dimension in a direction in a plane generally perpendicular to the optical axis, generally perpendicular to the direction of extension of the haptics. The so-called extension direction here may coincide with the radial direction or may be at an angle to the radial direction, that is, the so-called "haptic extends from the optical portion to the outer peripheral side" in the present invention includes the meaning that the extension direction of the haptic coincides completely with the radial direction and also includes the meaning that the haptic extends obliquely in the radial direction (that is, the extension direction of the haptic makes an angle to the radial direction).

The form of extension of the haptics is not particularly limited, and may be, for example, smoothly curved or straight with corners.

As an example, the thickenings may be integral of the haptics, i.e. the thickness of the haptics is greater than the width at all locations.

However, the present invention is not limited thereto. For example, the haptics have a root portion, which is a portion near the optic, a distal portion, which is a portion remote from the optic, and a middle portion, which is a portion between the root portion and the distal portion. The thickening may be provided at the distal end, or at both the distal end and the central portion, or at the root, distal end and central portion. The ratio of the thickness to the width may be the same or different between the root, distal end and the thickened portion of the middle portion.

For another example, the haptics may have a plurality of thickenings with spaces therebetween. The spacing between the plurality of thickenings may be the same or different.

Because the loop has a thickening part, the thickness of the thickening part is larger than the width, after the artificial lens is implanted into a human eye, the contact area of the loop and the human eye capsular bag is larger, so that the position stability of the artificial lens in the human eye capsular bag is higher.

Specifically, for example, when the thickness dimension is larger than the width dimension, the stress analysis of the intraocular lens may consider only the force in the radial direction without generating stress in the axial direction (optical axis direction) or the stress influence in the axial direction is small, but when the thickness dimension is smaller than the width dimension, the stress influence in the axial direction is also large in addition to the force in the radial direction, and there is a risk that an axial displacement error occurs after the lens is implanted in the human eye under a compressive force.

Therefore, by providing the thickened portion on the haptics, the risk of displacement errors of the intraocular lens in the optical axis direction can be reduced, and the positional stability of the intraocular lens can be improved.

Alternatively, the thickness of the thickening is 0.1 to 2.5mm, alternatively 0.4 to 1.5mm, and alternatively 0.5 to 1mm.

The invention will be described in more detail by means of a few specific examples.

< example 1.1>

FIG. 1a is a schematic front view of an intraocular lens according to one embodiment of the present invention; fig. 1b is a schematic side view of the intraocular lens.

As shown in fig. 1a and 1b, an intraocular lens 101 of the present embodiment has an optical portion 11 and haptics 21. The optical portion 11 has a convex lens shape as a whole. The optical portion 11 has an optical axis X1, and the optical portion 11 is substantially circular when viewed along the optical axis X1. The optical portion 11 is not limited to a circular shape, but this does not affect the meaning of the axial direction, the radial direction, and the circumferential direction defined by the optical axis. In the present embodiment, the pair of haptics 21 extend from the edge portions on both sides of the optical portion 11 toward the outer periphery around the optical axis X1. The portions of the two haptics 21 extending from the optic 11 are located on the same diameter through the optical axis X1. Alternatively, it can be said that the portions of the two haptics 21 protruding from the optical portion 11 are spaced 180 degrees apart in the circumferential direction of the optical portion 11. The haptics 21 are generally letter-C-shaped and extend along a rounded arcuate segment with free ends. That is, the intraocular lens in this embodiment is an intraocular lens having C-shaped haptics.

In the present embodiment, the thickness D1 and width H1 of the haptics 21 at each location are constant, that is, the ratio of thickness to width remains constant, and the thickness D1 is greater than the width H1.

It will be appreciated that thickness is the dimension of the haptics 21 in the direction of the optical axis X1 and width H1 is the dimension of the haptics 21 in a direction generally perpendicular to the direction of extension (which may be understood as the direction of extension of the arcuate line segment described above) and may be characterized by the distance between two parallel tangential lines.

With the above configuration, since the thickness D1 of the haptics 21 is larger than the width H1, i.e., the haptics 21 are thickened, the contact area of the haptics 21 with the human eye capsular bag can be increased, and positional stability such as rotational stability, centering stability, and axial stability in the state where the intraocular lens 101 is implanted into the human eye can be improved. Wherein rotational stability means that the position is kept stable in the circumferential direction centering on the optical axis X1; centering stability means that the position is kept stable in the radial direction centered on the optical axis X1; axial stability means that the position is kept stable in the direction of the optical X1.

As a specific example, the thickness D1 may be set to 0.58mm and the width H1 may be set to 0.35mm in a ratio of about 1.66:1.

It goes without saying that the present embodiment is not limited thereto, and the thickness D1 is freely set in the range of 0.1 to 2.5mm, 0.4 to 1.5mm, or 0.5 to 1 mm; the ratio of the thickness to the width can be freely set within a range of (1.01 to 5): 1, (1.1 to 2): 1 or (1.3 to 1.8): 1.

< example 1.2>

fig. 2b is a schematic side view of the intraocular lens.

The main difference between this embodiment and the above-described embodiment is that the structure of the haptics is different and the other structures are substantially the same, so the same reference numerals are used for them and detailed description thereof is omitted appropriately. This is also true in the description of the embodiments described later.

The intraocular lens in this embodiment is an intraocular lens with four-corner haptics. As shown in fig. 2a and 2b, the intraocular lens 102 of the present embodiment has an optical portion 11 and haptics 22. The number of the haptics 22 is 4, and the haptics 22 extend from the edge portion of the optical portion 11 to the outer peripheral side, wherein two of the haptics 22 extend upward in fig. 2a and two of the haptics 22 extend downward in fig. 2 a. The two upwardly extending haptics 22 extend first along a straight line and then curve to gradually approach, and similarly the two downwardly extending haptics 22 extend first along a straight line and then curve to gradually approach.

In this embodiment, the thickness D1 and width H1 of the haptics 22 at each location are constant, i.e., the ratio of thickness to width remains constant, and the thickness D1 is greater than the width H1.

With the above configuration, since the thickness D1 of the haptics 22 is larger than the width H1, i.e., the haptics 22 are thickened, the contact area of the haptics 22 with the human eye capsular bag can be increased, and positional stability, such as rotational stability, centering stability, and axial stability, of the intraocular lens 102 in a human eye state can be improved.

< example 1.3>

fig. 3b is a schematic side view of the intraocular lens.

The intraocular lens in this embodiment is an intraocular lens with a C-shaped intermediate hollowed-out haptic. As shown in fig. 3a, 3b, the intraocular lens 103 of the present embodiment has an optical portion 11 and two haptics 23. The haptics 23 extend from the optical portion 11 to the outer peripheral side, are folded back and connected to the optical portion 11 (i.e., the haptics 23 have hollowed portions or holes are formed in the haptics 23), and the folded back portions and the portions before folding back are curved as a whole, and the arcs of both are substantially parallel.

In the present embodiment, the thickness D1 and width H1 of the haptics 23 at each location are constant, i.e., the ratio of thickness to width remains constant, and the thickness D1 is greater than the width H1.

With the above structure, since the thickness D1 of the haptics 23 is larger than the width H1, i.e., the haptics 23 are thickened, the contact area of the haptics 23 with the human eye capsular bag can be increased, and positional stability, such as rotational stability, centering stability, and axial stability, of the intraocular lens 102 in a human eye state can be improved.

< example 1.4>

fig. 4b is a schematic side view of the intraocular lens.

The intraocular lens in this embodiment is an intraocular lens with four corner intermediate hollowed-out haptics. As shown in fig. 4a, 4b, the intraocular lens 104 of the present embodiment has an optic 11 and 4 haptics 24. The haptics 24 extend from the optical portion 11, are folded back and connected to the optical portion 11, and the portions before and after folding extend in a curved shape as a whole, and the portions before folding protrude toward the outer peripheral side and the portions after folding protrude toward the inner peripheral side.

In this embodiment, the thickness D1 and width H1 of the haptics 24 at each location are constant, i.e., the ratio of thickness to width remains constant, and the thickness D1 is greater than the width H1.

With the above configuration, since the thickness D1 of the haptics 24 is larger than the width H1, i.e., the haptics 24 are thickened, the contact area of the haptics 24 with the human eye capsular bag can be increased, and positional stability, such as rotational stability, centering stability, and axial stability, of the intraocular lens 102 in a human eye state can be improved.

< example 2.1>

fig. 5b is a schematic side view of the intraocular lens.

As shown in fig. 5a, 5b, the intraocular lens 201 of the present embodiment has an optical portion 11 and two haptics 21A.

The structure of this embodiment is substantially the same as that shown in fig. 1A, 1b, with the main difference that in this embodiment the thickness of the haptics 21A varies in the direction of extension.

Specifically, as shown in FIG. 5b, haptic 21A has a root portion 2a, a distal end portion 2c and a middle portion 2b, root portion 2a being a portion near optical portion 11, distal end portion 2c being a portion distant from optical portion 11, and middle portion 2b being a portion between root portion 2a and distal end portion 2c. The thickness D21 of the root portion 2a is smaller than the thickness D22 of the distal end portion 2c. The thickness of the intermediate portion 2b may be between the thickness D21 of the root portion 2a and the thickness D22 of the distal end portion 2c, or may be equal to the thickness D21 of the root portion 2a or the thickness D22 of the distal end portion 2c.

The root portion 2a, distal end portion 2C and intermediate portion 2b are not strictly divided, and as an example of a division, see fig. 5a, in which 3 virtual circular arcs C1, C2, C3 are drawn, wherein C1 passes through points on the outermost peripheral side of the haptic 21A, and these 3 circular arcs C1, C2, C3 are arranged at equal intervals in the radial direction from a virtual circle passing through the outer edge of the optical zone 11. In this state, the portion of the haptic 21A on the inner peripheral side of the circular arc C3 is the root 2a, the portion between the circular arcs C3 and C2 is the intermediate portion 2b, and the portion on the outer peripheral side of the circular arc C2 is the distal portion 2C. However, the present invention is not limited thereto, and may be divided by the length along the extending direction of the haptics.

In addition, the width H2 of the haptics 21A remains constant as a whole.

Of the root portion 2a, the distal end portion 2c, and the intermediate portion 2b, the thickness D22 of the distal end portion 2c is greater than the width H2. The root portion 2a and the middle portion 2b may have a thickness greater than the width H2, or may have a thickness equal to or smaller than the width H2.

In this way, since the thickness D22 of the distal end portion is greater than the width H2, the haptic 22A has a thickened portion, so that the contact area between the haptic and the human eye capsular bag can be increased, and the positional stability after implantation of the intraocular lens 201 can be improved.

In other words, a thickening is provided in the distal end portion 2c, while the root portion 2a or the middle portion 2b may or may not be provided with a thickening. As an example, a thickening may be provided at the distal end and the middle portion, or at the root portion, the distal end and the middle portion. The ratio of the thickness to the width may be the same or different between the root, distal end and the thickened portion of the middle portion.

In addition, the thickness of the distal end portion 2c may be kept constant, or may be continuously changed with the intermediate portion 2b (or with the intermediate portion 2b and the root portion 2 a).

As an example, the thickness D22 of the distal end portion 2c may be set to 0.7mm, the thickness of the root portion 2a may be set to 0.58mm, and the width H2 may be set to 0.37mm.

It goes without saying that the invention is not limited thereto. The thickness of each portion of the haptics 21A may be freely set in the range of 0.1 to 2.5mm, 0.4 to 1.5mm, or 0.5 to 1 mm.

As an example, the thickness dimension of the haptics 21A tends to become larger as they approach the outermost portion (outermost portion of the distal end portion), and the ratio of the maximum portion thickness (or average thickness of the distal end portion) to the width may be (5:1 to 1.01:1), (3:1) to (1.1:1), or (2:1) to (1.2:1). The ratio of root minimum site thickness (or root average thickness) to width may be (3:1) - (1.01:1), (2:1) - (1.1:1), or (1.6:1) - (1.2:1).

< example 2.2>

fig. 6b is a schematic side view of the intraocular lens.

As shown in fig. 6a, 6b, intraocular lens 202 of this embodiment has an optic 11 and 4 haptics 22A. The thickness of the haptics 22A varies in the direction of extension. In addition, the width H2 of the haptics 22A remains constant in the extending direction.

In haptic 22A, distal portion thickness D22 is greater than width H2. The root and middle portions may have a thickness greater than the width H2, or may have a thickness equal to or less than the width H2.

In other words, a thickening is provided at the distal end, while the root or middle may or may not be provided with a thickening. As an example, a thickening may be provided at the distal end and the middle portion, or at the root portion, the distal end and the middle portion. The ratio of the thickness to the width may be the same or different between the root, distal end and the thickened portion of the middle portion.

In addition, the thickness of the distal portion may be constant or may vary continuously with the middle portion (or with the middle portion and the root portion).

As an example, the thickness D22 of the distal end portion may be set to 0.7mm, the thickness of the root portion may be set to 0.58mm, and the width H2 may be set to 0.37mm.

It goes without saying that the invention is not limited thereto. The thickness of each portion of the haptics 22A may be freely set within a range of 0.1 to 2.5mm, 0.4 to 1.5mm, or 0.5 to 1 mm.

As an example, the thickness dimension of the haptics 22A tends to become progressively larger as they approach the outermost portion (outermost portion of the distal portion), and the ratio of the maximum portion thickness (or average thickness of the distal portion) to the width may be (5:1 to 1.01:1), (3:1) to (1.1:1), or (2:1) to (1.2:1). The ratio of root minimum site thickness (or root average thickness) to width may be (3:1) - (1.01:1), (2:1) - (1.1:1), or (1.6:1) - (1.2:1).

< example 2.3>

fig. 7b is a schematic side view of the intraocular lens.

As shown in fig. 7a, 7b, the intraocular lens 203 of the present embodiment has an optical portion 11 and haptics 23A. The thickness of the haptics 23A varies in the direction of extension. In addition, the width H2 of the haptics 23A remains constant in the extending direction.

It goes without saying that the invention is not limited thereto. The thickness of each portion of the haptics may be freely set in the range of 0.1 to 2.5mm, 0.4 to 1.5mm, or 0.5 to 1 mm.

As an example, the thickness dimension of the haptics tends to become progressively larger as they approach the outermost portion (outermost portion of the distal end portion), and the ratio of the maximum portion thickness (or average thickness of the distal end portion) to the width may be (5:1 to 1.01:1), (3:1) to (1.1:1), or (2:1) to (1.2:1). The ratio of root minimum site thickness (or root average thickness) to width may be (3:1) - (1.01:1), (2:1) - (1.1:1), or (1.6:1) - (1.2:1).

< example 2.4>

FIG. 8a is a schematic front view of an intraocular lens according to one embodiment of the present invention; fig. 8b is a schematic side view of the intraocular lens.

As shown in fig. 8a, intraocular lens 204 of this embodiment has an optic 11 and haptics 24A. The thickness of haptics 24A varies in the direction of extension. In addition, the width H2 of the haptics 24A remains constant in the extending direction.

Specifically, in the present embodiment, in the haptics 24A, the thickness D22 of the distal end portions is greater than the width H2. The root and middle portions may have a thickness greater than the width H2, or may have a thickness equal to or less than the width H2.

< example 3.1>

FIG. 9a is a schematic front view of an intraocular lens according to an embodiment of the present invention; fig. 9b is a schematic side view of the intraocular lens.

As shown in fig. 9a and 9B, the intraocular lens 301 of the present embodiment has an optical portion 11 and haptics 21B. The thickness D3 of the haptics 21B remains constant in the direction of extension and, in addition, the width of the haptics 21B varies in the direction of extension.

For example, haptic 21B may have a thickness D3 of 0.1 to 2.5mm, 0.4 to 1.5mm, or 0.5 to 1mm.

The width of the haptics 21B tends to decrease gradually as they approach the outermost peripheral portion, and the ratio of the root maximum portion thickness to the width is preferably 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1. The ratio of the thickness to the width of the minimum distal portion is preferably 3:1 to 1.01:1, less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1.

As an example, the thickness D3 is set to 0.58mm, the width H31 of the root maximum portion may be set to 0.57mm, and the width H32 of the distal minimum portion may be set to 0.35mm.

The width dimension of the haptics 21B may be gradually increased as they approach the outermost Zhou Bucheng, and the ratio of the root minimum portion thickness to the width may be preferably 3:1 to 1.01:1, and less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1. The ratio of the thickness to the width of the maximum portion of the distal end is 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1.

For example, the width H31 of the root portion may be constant, the width H32 of the distal end portion may be constant, and the middle portion may be smoothly connected therebetween. As an example, the thickness D3 is set to 0.58mm, the width H31 of the root portion may be set to 0.57mm, and the width H32 of the distal end portion may be set to 0.35mm.

< example 3.2>

FIG. 10a is a schematic front view of an intraocular lens according to one embodiment of the present invention; fig. 10b is a schematic side view of the intraocular lens.

As shown in fig. 10a and 10B, the intraocular lens 302 of the present embodiment has an optical portion 11 and haptics 22B. The thickness D3 of the haptics 22B remains constant in the direction of extension and, in addition, the width of the haptics 21B varies in the direction of extension.

For example, the thickness D3 of the haptics 22B may be 0.1-2.5 mm, 0.4-1.5 mm, or 0.5-1 mm.

The width of the haptics 22B tends to decrease as they approach the outermost peripheral portion, and the ratio of the root maximum portion thickness to the width is preferably 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1. The ratio of the thickness to the width of the minimum distal portion is preferably 3:1 to 1.01:1, less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1.

As an example, the thickness D3 is set to 0.58mm, the width H31 of the root maximum portion may be set to 0.55mm, and the width H32 of the distal minimum portion may be set to 0.35mm.

The width dimension of the haptics 22B may be gradually increased as they approach the outermost Zhou Bucheng, and the ratio of the root minimum portion thickness to the width may be preferably 3:1 to 1.01:1, and less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1. The ratio of the thickness to the width of the maximum portion of the distal end is 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1.

For example, the width H31 of the root portion may be constant, the width H32 of the distal end portion may be constant, and the middle portion may be smoothly connected therebetween. As an example, the thickness D3 is set to 0.58mm, the width H31 of the root portion may be set to 0.55mm, and the width H32 of the distal end portion may be set to 0.35mm.

< example 3.3>

FIG. 11a is a schematic front view of an intraocular lens according to an embodiment of the present invention; fig. 11b is a schematic side view of the intraocular lens.

As shown in fig. 11a and 11B, the intraocular lens 303 of the present embodiment has an optical portion 11 and haptics 23B. The thickness D3 of the haptics 23B remains constant in the direction of extension and, in addition, the width of the haptics 23B varies in the direction of extension.

For example, haptic 23B may have a thickness D3 of 0.1 to 2.5mm, 0.4 to 1.5mm, or 0.5 to 1mm.

The width of the haptics 23B tends to decrease as they approach the outermost peripheral portion, and the ratio of the root maximum portion thickness to the width is preferably 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1. The ratio of the thickness to the width of the minimum distal portion is preferably 3:1 to 1.01:1, less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1.

As an example, the thickness D3 is set to 0.58mm, the width H31 of the root maximum portion may be set to 0.46mm, and the width H32 of the distal minimum portion may be set to 0.27mm.

The width dimension of the haptics 23B may be gradually increased as they approach the outermost Zhou Bucheng, and the ratio of the root minimum portion thickness to the width may be preferably 3:1 to 1.01:1, and less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1. The ratio of the thickness to the width of the maximum portion of the distal end is 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1.

For example, the width H31 of the root portion may be constant, the width H32 of the distal end portion may be constant, and the middle portion may be smoothly connected therebetween. As an example, the thickness D3 is set to 0.58mm, the width H31 of the root portion may be set to 0.46mm, and the width H32 of the distal end portion may be set to 0.27mm.

< example 3.4>

FIG. 12a is a schematic front view of an intraocular lens according to an embodiment of the present invention; fig. 12b is a schematic side view of the intraocular lens.

As shown in fig. 12a and 12B, the intraocular lens 304 of the present embodiment has an optical portion 11 and haptics 24B.

The thickness D3 of the haptics 24B remains constant in the direction of extension and, in addition, the width of the haptics 24B varies in the direction of extension.

For example, haptic 24B may have a thickness D3 of 0.1 to 2.5mm, 0.4 to 1.5mm, or 0.5 to 1mm.

The width of the haptics 24B tends to decrease as they approach the outermost peripheral portion, and the ratio of the root maximum portion thickness to the width is preferably 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1. The ratio of the thickness to the width of the minimum distal portion is preferably 3:1 to 1.01:1, less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1.

As an example, the thickness D3 is set to 0.58mm, the width H31 of the root maximum portion may be set to 0.4mm, and the width H32 of the distal minimum portion may be set to 0.25mm.

The width dimension of the haptics 24B may be gradually increased as they approach the outermost Zhou Bucheng, and the ratio of the root minimum portion thickness to the width may be preferably 3:1 to 1.01:1, and less preferably 2:1 to 1.1:1, and more preferably 1.6:1 to 1.2:1. The ratio of the thickness to the width of the maximum portion of the distal end is 5:1 to 1.01:1, less preferably 3:1 to 1.1:1, and more preferably 2:1 to 1.2:1.

For example, the width H31 of the root portion may be constant, the width H32 of the distal end portion may be constant, and the middle portion may be smoothly connected therebetween. As an example, the thickness D3 is set to 0.58mm, the width H31 of the root portion may be set to 0.4mm, and the width H32 of the distal end portion may be set to 0.25mm.

< example 4.1>

FIG. 13a is a schematic front view of an intraocular lens according to an embodiment of the present invention; fig. 13b is a schematic side view of the intraocular lens.

The intraocular lens 401 of the present embodiment shown in fig. 13a, 13b has an optical portion 11 and haptics 21C.

The haptics 21C are of greater thickness than their width dimension in the direction of extension, and the haptics vary in width and thickness but remain at the root, middle and distal portions with corresponding proportions of haptic thickness and width, respectively. The ratio can be set according to the following table.

TABLE 1 ratio of haptic thickness to Width at different regions

Region(s)	Haptic-shaped length region	Thickness to width ratio
			Heel part	5～8	1.1:1～1.3:1
Middle part	8～11	1.3:1～1.5:1
			Distal end portion	11～13.5	1.5:1～1.8:1

The "haptic-shaped length" herein refers to a length calculated from a junction of the haptic and the optical portion along an extending direction of the haptic. As an example, the direction of extension of the haptics may coincide with the radial direction, as other examples, the direction of extension of the haptics may also be at an angle to the radial direction, i.e. inclined with respect to the radial direction. The haptics may extend along straight lines, along a rounded curve, or along a portion thereof, and along other portions thereof.

Referring to the table, the thickness and the width of the loop are close to each other, the ratio (ratio) of the thickness to the width of the loop is small, and the loop can be ensured to have large supporting force in the radial direction; the proportion of the thickness and the width of the loop at the middle part is moderate, and the compression stress is released; the haptic has a maximum thickness at the distal end and a smaller width dimension in a larger ratio, thus maximizing the contact area of the haptic edge with the human eye capsular bag.

As an example, the haptics have a minimum thickness D41 at the root of 0.58mm and a maximum thickness D42 at the distal end of 0.7mm; having a maximum width H41 at the root of 0.57mm; the width H42 at the distal end is 0.35.

< example 4.2>

FIG. 14a is a schematic front view of an intraocular lens according to an embodiment of the present invention; fig. 14b is a schematic side view of the intraocular lens.

As shown in fig. 14a and 14b, intraocular lens 402 of the present embodiment has an optic 11 and haptics 22C.

The haptics 22C are of greater thickness than their width dimension in the direction of extension, with varying widths and thicknesses of the haptics being maintained at the root, middle and distal portions, with corresponding proportions of haptic thickness and width, respectively. The ratio can be set as in table 1 above.

As in the previous embodiments, the thickness and width dimensions of the haptics at the root are similar, and the ratio of the thickness to the width dimensions is small, so that the haptics can be ensured to have larger supporting force in the radial direction; the proportion of the thickness and the width of the loop at the middle part is moderate, and the compression stress is released; the haptic has a maximum thickness at the distal end and a smaller width dimension in a larger ratio, thus maximizing the contact area of the haptic edge with the human eye capsular bag.

As an example, the haptics have a minimum thickness D41 at the root of 0.58mm and a maximum thickness D42 at the distal end of 0.7mm; having a maximum width H41 at the root of 0.55mm; the width H42 at the distal end is 0.35.

< example 4.3>

FIG. 15a is a schematic front view of an intraocular lens according to an embodiment of the present invention; fig. 15b is a schematic side view of the intraocular lens.

As shown in fig. 15a and 15b, the intraocular lens 403 of the present embodiment has an optical portion 11 and haptics 23C.

The haptics 23C are of greater thickness than their width dimension in the direction of extension, and the haptics vary in width and thickness but remain at the root, middle and distal portions with corresponding proportions of haptic thickness and width, respectively. The ratio can be set as in table 1 above.

As an example, the haptics have a minimum thickness D41 at the root of 0.58mm and a maximum thickness D42 at the distal end of 0.7mm; having a maximum width H41 at the root of 0.46mm; the width H42 at the distal end is 0.27.

< example 4.4>

FIG. 16a is a schematic front view of an intraocular lens according to an embodiment of the present invention; fig. 16b is a schematic side view of the intraocular lens.

As shown in fig. 16a, 16b, intraocular lens 404 of the present embodiment has an optic 11 and haptics 24C.

The haptics 24C are of greater thickness than their width dimension in the direction of extension, and the haptics vary in width and thickness but remain at the root, middle and distal portions with corresponding proportions of haptic thickness and width, respectively. The ratio can be set as in table 1 above.

As an example, the haptics have a minimum thickness D41 at the root of 0.58mm and a maximum thickness D42 at the distal end of 0.7mm; having a maximum width H41 at the root of 0.4mm; the width H42 at the distal end is 0.35.

< other examples >

Figures 17 a-17 f illustrate some embodiments of the invention. In these embodiments, the thickness of the haptics varies in the direction of extension. For example, in FIG. 17a, the lower surface of the haptic (the surface substantially perpendicular to the width direction) is provided with a plurality of protrusions where the haptic is thickened to a thickness greater than the width. The projections may be equally spaced or not equally spaced. I.e. the haptics have a plurality of thickenings, which may or may not be equally spaced. It will be appreciated that the thickenings formed by the plurality of protrusions may also be formed on the upper surface of the haptics.

In fig. 17b, the lower surface of the haptic is wavy or sinusoidal (or cosine curved) during testing, thus giving the haptic a plurality of thickenings. It will be appreciated that the thickening formed by the plurality of wavy or sinusoidal (or cosine-curved) projections may also be formed on the upper surface of the haptics.

In fig. 17c, a plurality of protrusions are provided on both the upper and lower surfaces of the haptic, the protrusions between the upper and lower surfaces being disposed opposite each other, so that the haptic has a plurality of thickened portions. It will be appreciated that the protrusions between the upper and lower surfaces may also be partially or fully offset.

In fig. 17d, the upper and lower surfaces of the haptics are wavy and the peaks between the upper and lower surfaces are disposed opposite the peaks, thus providing the haptics with multiple thickenings. It will be appreciated that the peaks and peaks between the upper and lower surfaces may be partially or fully offset.

In fig. 17e, the lower surface of the haptics is formed in a stepped shape with a greater thickness at the distal end side. It will be appreciated that the step may also be formed on the upper surface of the haptics or may be of lesser thickness on the distal side.

In fig. 17f, the lower surface of the haptics is beveled and the thickness increases as it approaches the distal end along the extension direction. It will be appreciated that the slope may also be formed on the lower surface of the haptics or may be of lesser thickness on the distal side.

The foregoing description of the preferred embodiments of the invention is not intended to be limiting, but rather is intended to cover all modifications, equivalents, alternatives, and improvements that fall within the spirit and scope of the invention.

In the above embodiments, four types of haptics are illustrated, however, it goes without saying that the present invention is also applicable to intraocular lenses having other haptic shapes. The number of haptics is also not limited and may be 3, for example.

Claims

1. An intraocular lens comprising an optical portion having an optical axis and haptics extending from the optical portion to an outer peripheral side,

the haptics have a thickening portion having a thickness greater than a width.

2. The intraocular lens of claim 1, wherein the thickening extends throughout the entirety of the haptics.

3. The intraocular lens of claim 1 wherein said haptic has a plurality of said thickenings with spaces therebetween.

4. The intraocular lens of claim 1 wherein the thickness of the haptics is constant in the direction of extension.

5. The intraocular lens of claim 1 wherein the haptic thickness varies in the direction of extension.

6. The intraocular lens of claim 1 wherein the width of the haptics is constant in the direction of extension.

7. The intraocular lens of claim 1 wherein the width of the haptics varies in extension.

8. The intraocular lens of any one of claims 1-7 wherein the haptic thickness becomes progressively greater toward the peripheral side.

9. The intraocular lens of any one of claims 1-7, wherein the haptic has a root proximal to the optic and a distal end distal from the optic, the distal end having the thickened portion.

10. The intraocular lens of any one of claims 1-7 wherein the haptic has a root portion proximal to the optic, a distal end portion distal from the optic and a central portion connected between the root portion and the distal end portion,

the haptic has a thickness to width ratio at the root portion that is less than a thickness to width ratio at the distal end portion.

11. The intraocular lens of claim 10 wherein the haptic thickness to width ratio at the central portion is between the root thickness to width ratio and the distal portion thickness to width ratio.

12. Intraocular lens according to any one of claims 1 to 7, characterized in that the thickness of the thickening is 0.1-2.5 mm, 0.4-1.5 mm or 0.5-1 mm.

13. Intraocular lens according to any one of claims 1 to 7, characterized in that the ratio of the thickness to the width of the thickening is (1.01-5): 1, (1.1-2): 1 or (1.3-1.8): 1.

14. The intraocular lens according to any one of claims 1 to 7, wherein the haptic has a thickness that is greater closer to the outer periphery, the ratio of the thickness to the width of the region of greatest thickness being (5:1 to 1.01:1), (3:1) to (1.1:1) or (2:1) to (1.2:1), and the ratio of the thickness to the width of the region of least thickness being (3:1) to (1.01:1), (2:1) to (1.1:1) or (1.6:1) to (1.2:1).

15. The intraocular lens according to any one of claims 1 to 7, wherein the thickness of the haptic is smaller closer to the outer periphery or further from the optic in the direction of extension, the ratio of the thickness to the width of the region of greatest thickness is (5:1 to 1.01:1), (3:1) to (1.1:1) or (2:1) to (1.2:1), and the ratio of the thickness to the width of the region of smallest thickness is (3:1) to (1.01:1), (2:1) to (1.1:1) or (1.6:1) to (1.2:1).

16. The intraocular lens of any one of claims 1-7 wherein the haptic thickness to width ratio in different regions satisfies the relationship:

The "haptic length" refers to a length calculated from a junction of the haptic and the optical portion along an extending direction of the haptic.