CN116392285B - Novel bone taking device - Google Patents
Novel bone taking device Download PDFInfo
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- CN116392285B CN116392285B CN202310674167.5A CN202310674167A CN116392285B CN 116392285 B CN116392285 B CN 116392285B CN 202310674167 A CN202310674167 A CN 202310674167A CN 116392285 B CN116392285 B CN 116392285B
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- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 89
- 230000007246 mechanism Effects 0.000 claims abstract description 40
- 210000003625 skull Anatomy 0.000 claims abstract description 33
- 239000012634 fragment Substances 0.000 claims abstract description 32
- 238000003306 harvesting Methods 0.000 claims abstract description 9
- 238000000605 extraction Methods 0.000 claims description 11
- 230000000149 penetrating effect Effects 0.000 claims description 4
- 239000004677 Nylon Substances 0.000 claims description 3
- 238000005553 drilling Methods 0.000 claims description 3
- 229920001778 nylon Polymers 0.000 claims description 3
- 210000005013 brain tissue Anatomy 0.000 abstract description 11
- 230000006378 damage Effects 0.000 abstract description 7
- 210000004556 brain Anatomy 0.000 abstract description 4
- 241001465754 Metazoa Species 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 238000002474 experimental method Methods 0.000 abstract description 3
- 210000004204 blood vessel Anatomy 0.000 abstract description 2
- 210000005036 nerve Anatomy 0.000 abstract description 2
- 241000700159 Rattus Species 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000003925 brain function Effects 0.000 description 1
- 210000001951 dura mater Anatomy 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Surgical Instruments (AREA)
Abstract
The invention provides a novel bone harvesting machine, which relates to the technical field of animal brain experiments and comprises the following components: the locking mechanism comprises a positioning structure and a guiding structure, wherein the two positioning structures are fixed in a drilled hole drilled before skull cutting and used for limiting the starting position and the ending position of the guiding structure, and the guiding structure moves from the positioning structure at the starting position to a gap between the skull and a bone fragment, and the positioning structure at the ending position stops moving; the tail ends of the traction mechanisms are respectively connected with the two ends of the guide structure, the guide structure can move in a gap between the skull and the bone fragments by adjusting the two traction mechanisms, and can encircle the outer side of the bone fragments to tightly hold the bone fragments, so that the problems that when the bone fragments are used for smaller bone fragments, the grabbing effect is not ideal, the stability is poor, the bone fragments are easy to shift and drop, and even secondary damage to surrounding brain tissues, blood vessels, nerves and the like is caused are solved.
Description
Technical Field
The invention relates to the technical field of animal brain experiments, in particular to a novel bone taking device.
Background
In brain function research, animals such as rats are often used as experimental objects, especially in research in the field of neuroscience, subsequent operations after the skull of the rat is perforated are more conventional means, the experiment needs to determine the three-dimensional coordinates (X, Y, Z axes) of the perforated position, then the corresponding skull position is perforated, and then bone fragments are removed by a bone harvesting device, so that the brain tissue of the rat is further operated.
However, the three-jaw bone holder is mainly applied to the traditional bone taking machinery at present, and when the bone holder is used for grabbing a large bone piece with good integrity, the damage to brain tissues around the bone piece end is small, but when the bone holder is used for small bone pieces, the grabbing effect is not ideal, meanwhile, the stability is poor, the bone piece is easy to shift and drop, and even secondary damage to the surrounding brain tissues, blood vessels, nerves and the like is caused.
Disclosure of Invention
The invention provides a novel bone harvesting machine, which specifically comprises:
the locking mechanism comprises a positioning structure and a guiding structure, wherein the two positioning structures are fixed in a drilled hole drilled before skull cutting and used for limiting the starting position and the ending position of the guiding structure, and the guiding structure moves from the positioning structure at the starting position to a gap between the skull and a bone fragment, and the positioning structure at the ending position stops moving;
the tail ends of the two traction mechanisms are respectively connected with the two ends of the guide structure, the guide structure can move in a gap between the skull and the bone fragments by adjusting the two traction mechanisms, and the guide structure can encircle the outer side of the bone fragments to hug the bone fragments.
Further, the device also comprises an installation part; the mounting piece of the mounting part is preferably of an I-shaped structure, and the left side and the right side of the rear end of the mounting piece and the right side of the front end of the mounting piece are respectively provided with a rotary hole.
Further, a sliding hole is formed in the left side of the front end of the mounting piece, and the shape of the sliding hole is preferably a round corner rectangle; and the middle part of the inner wall of the sliding hole is provided with guide grooves which are symmetrical front and back and are used for limiting and guiding one of the positioning structures.
Further, a first positioning structure is inserted into the rotary hole, and the first positioning structure is rotatably connected with the mounting piece; the other positioning structure is inserted into the sliding hole and is in sliding connection with the mounting piece, and the other positioning structure is used for adjusting the distance between the two positioning structures so as to adapt to the drill holes with different distances on the skull.
Further, the positioning structure comprises a guide part; the guide part comprises a guide piece, a support piece and a limiting piece; the two guide parts are respectively inserted into the rotating hole and the sliding hole at the front end of the mounting piece; the upper end of the guide piece is provided with a handle; the lower end of the guide piece is provided with threads for installing the limiting piece; the thread lower end of the guide piece is provided with a thread hole, and the thread hole is preferably round; the support piece is of a basin-shaped structure, and a screw hole is formed in the support piece; the supporting piece is connected to the outer side of the thread of the guiding piece through a screw hole and is used for limiting the depth of the bottom of the guiding piece penetrating into the skull drilling hole; the limiting piece is internally provided with a through hole, and is inserted into the guide groove; the limiting piece is fixedly connected to the outer side of the left guide piece.
Further, the middle part fixedly connected with of guide structure is used for restricting the limit structure of guide structure position.
Further, the guide structure includes a locking portion; the locking part comprises a locking wire and a lead slider; the locking wire is preferably a medical nylon wire, and the tail end of the locking wire is spirally curled; the limiting structure is specifically a lead sliding block, the section of the lead sliding block is of a T-shaped structure, and two ends of the lead sliding block are respectively connected with the head ends of the two locking wires.
Further, the two traction mechanisms are inserted into the two rotary holes at the rear end of the mounting piece, and are in rotary connection with the mounting piece; the lower extreme of traction mechanism sets up the storage structure.
Further, the traction mechanism comprises a traction part; the traction part comprises a traction piece and a wire box; the upper end of the traction piece is fixedly connected with a handle for rotating the traction piece; the storage structure is specifically a wire box; the lower extreme fixedly connected with line box of traction element, and the tail end of locking line is accomodate to line box inside.
Further, the right side of the mounting piece is fixedly connected with a connecting plate; the right side of the connecting plate is fixedly connected with a holding frame.
Advantageous effects
The experimenter needs to determine the distance between two positioning structures and the penetration depth according to the drill hole on the skull, then holds the device, penetrates the two positioning structures into the drill hole, cuts the guide structure into the drill hole when the guide structure is at the initial position by adjusting the angle of the positioning structure, drives the guide structure to slide towards the end position along the track of the cut seam by rotating the traction mechanism on one side, enables the guide structure to be distributed into the cut seam, gradually tightens the guide structure around the bone piece by rotating the traction mechanism on the other side after the guide structure reaches the end position, and holds the bone piece tightly, and can stably and safely take out the bone piece after the device is lifted;
the structure is safer for the bone holder, the vertical downward action is converted into the horizontal action when the guiding structure holds the bone fragments tightly when the bone holder clamps the bone fragments, the brain tissues can be effectively prevented from being stabbed, the safety is improved, the guiding structure holds the bone fragments more than the contact points of the bone fragments, the bone fragments can be fixed more stably after the bone fragments are held tightly, the bone fragments are effectively prevented from falling off, and secondary damage is caused to the brain tissues.
Drawings
In order to more clearly illustrate the technical solution of the embodiments of the present invention, the drawings of the embodiments will be briefly described below.
The drawings described below are only for illustration of some embodiments of the invention and are not intended to limit the invention.
In the drawings:
fig. 1 shows a schematic perspective view of the whole of a novel bone harvesting machine according to an embodiment of the present invention.
Fig. 2 shows an exploded view of the entirety of a novel bone extraction instrument according to an embodiment of the invention.
Fig. 3 shows a schematic perspective cross-sectional view of a mounting portion of a novel bone extraction instrument according to an embodiment of the invention.
Fig. 4 shows an enlarged partial schematic view of the novel bone extraction mechanism at a of fig. 3, in accordance with an embodiment of the invention.
Fig. 5 shows a schematic assembly of the left guide of the novel bone extraction device according to an embodiment of the invention.
Fig. 6 shows an enlarged partial schematic view of the novel bone extraction mechanism at B of fig. 5, in accordance with an embodiment of the invention.
Fig. 7 is a schematic perspective view showing a traction part of the novel bone removing device according to the embodiment of the present invention.
Fig. 8 shows an enlarged partial schematic view of the novel bone extraction mechanism at C of fig. 7, in accordance with an embodiment of the invention.
Fig. 9 is a schematic perspective view showing a locking part of the novel bone removing device according to the embodiment of the present invention.
Fig. 10 shows a partially enlarged schematic illustration of the novel bone extraction mechanism at D of fig. 9 in accordance with an embodiment of the invention.
List of primary reference numerals
1. A mounting part; 101. a mounting member; 102. a rotation hole; 103. a sliding hole; 104. a guide groove;
2. a guide part; 201. a guide member; 202. a support; 203. a limiting piece;
3. a traction section; 301. a traction member; 302. a wire box;
4. a locking part; 401. locking the wire; 402. a lead slider;
5. a grip portion; 501. a connecting plate; 502. a holding frame.
Detailed Description
In order to make the objects, aspects and advantages of the technical solution of the present invention more clear, the technical solution of the embodiment of the present invention will be clearly and completely described below with reference to the accompanying drawings of the specific embodiment of the present invention.
Examples: please refer to fig. 1 to 10:
embodiment one:
as shown in fig. 1 and 2, the present invention proposes a novel bone harvesting device, comprising:
the locking mechanism comprises a positioning structure and a guiding structure, wherein the two positioning structures are fixed in a drilled hole drilled before skull cutting and used for limiting the starting position and the ending position of the guiding structure, and the guiding structure moves from the positioning structure at the starting position to a gap between the skull and the bone fragments, and the positioning structure at the ending position stops moving;
the tail ends of the two traction mechanisms are respectively connected with two ends of the guide structure, the guide structure can move in a gap between the skull and the bone fragments by adjusting the two traction mechanisms, and the guide structure can encircle the outer side of the bone fragments to hug the bone fragments.
As shown in fig. 3 and 4, the device further comprises a mounting part 1; the mounting piece 101 of the mounting part 1 is preferably in an I-shaped structure, and the left side and the right side of the rear end of the mounting piece 101 and the right side of the front end are respectively provided with a rotary hole 102; the mounting piece 101 is used for mounting other parts of the device, and meanwhile, the mounting piece 101 adopts an I-shaped structure, so that the overall weight of the device can be effectively reduced, and the device is easier to operate in a handheld manner; the mounting piece 101 is provided with three rotary holes 102, and two traction mechanisms and one positioning structure are respectively mounted.
As shown in fig. 3 and 4, a sliding hole 103 is formed on the left side of the front end of the mounting member 101, and the shape of the sliding hole 103 is preferably a rounded rectangle; the middle part of the inner wall of the sliding hole 103 is provided with a guide groove 104 which is symmetrical in front-back and is used for limiting and guiding one of the positioning structures; the mounting member 101 is provided with a sliding hole 103 for mounting another positioning structure, and simultaneously guides and limits the sliding of the positioning structure through a guiding groove 104 inside the positioning structure.
Wherein, as shown in fig. 5 and 6, the first positioning structure is inserted into the rotation hole 102, and the first positioning structure is rotatably connected with the mounting member 101; the other positioning structure is inserted into the sliding hole 103 and is slidably connected with the mounting piece 101, so as to adjust the interval between the two positioning structures, thereby adapting to the different interval drilling holes on the skull.
Wherein, as shown in fig. 5 and 6, the positioning structure comprises a guiding part 2; the guide part 2 comprises a guide piece 201, a support piece 202 and a limiting piece 203; two guide portions 2 are inserted into the rotation hole 102 and the slide hole 103 at the front end of the mounting member 101, respectively; the right guide part 2 rotates in the rotary hole 102, so that the line hole orientation at the bottom end of the guide piece 201 is changed, and after the guide part 2 is inserted into the drill hole, the line hole can be adjusted to be aligned with the cutting seam, so that the locking line 401 is conveniently introduced into the cutting seam between the skull and the bone fragments;
preferably, the upper end of the guide 201 is provided with a handle; the device can be operated conveniently and rapidly by an operator through the handle;
preferably, the lower end of the guide 201 is threaded for mounting the limiting member 203;
preferably, the thread lower end of the guide 201 is provided with a thread hole, and the thread hole is preferably circular; the inside of the wire hole passes through the locking wire 401 and restrains the starting position and the ending position of the locking wire 401, so that the locking wire 401 is aligned with a cutting seam between the skull and the bone fragments when in the starting position, and the locking wire 401 is conveniently inserted into the cutting seam gradually;
preferably, the supporting member 202 has a basin-shaped structure, and a screw hole is formed in the supporting member 202; the supporting piece 202 is connected to the outer side of the thread of the guiding piece 201 through a screw hole and is used for limiting the depth of the bottom of the guiding piece 201 penetrating into the skull drill hole; the position of the supporting piece 202 outside the guide piece 201 can be adjusted by rotating the supporting piece 202, so that the protruding length of the lower end of the guide piece 201 is adjusted, and the supporting piece 202 is supported at the upper end of a skull drill hole when the position of the guide piece 201 is fixed because the diameter of the supporting piece 202 is larger than that of the skull drill hole, so that the guide piece 201 is prevented from penetrating into the drill hole too deeply, and the damage of the guide piece 201 to brain tissues is caused;
preferably, a through hole is formed in the limiting piece 203, and the limiting piece 203 is inserted into the guide groove 104; the limiting piece 203 is fixedly connected to the outer side of the left guide piece 201; the sliding of the left guide 201 is guided and restrained by the stopper 203.
As shown in fig. 7 and 8, the middle part of the guiding structure is fixedly connected with a limiting structure for limiting the position of the guiding structure; the guiding structure is limited through the limiting structure, so that the guiding structure is prevented from being sunk into the cutting seam to injure brain tissues deeply.
Wherein, as shown in fig. 9 and 10, the guiding structure comprises a locking part 4; the locking part 4 comprises a locking wire 401 and a lead slider 402; the locking wire 401 is preferably medical nylon wire, and the tail end of the locking wire 401 is spirally curled; the locking part 4 is gradually arranged into the cutting seam under the drive of the traction mechanism, the cut bone fragments are surrounded, and the locking part 4 is contracted by matching with the traction mechanism, so that the cut bone fragments are tightly held, and the cut bone fragments can be safely and stably taken off from the skull;
preferably, the limiting structure is specifically a lead slider 402, the section of the lead slider 402 is of a T-shaped structure, and two ends of the lead slider 402 are respectively connected with the head ends of two locking wires 401; the width of lead slider 402 upper end is greater than the width of cutting seam, and the width of lead slider 402 lower extreme is less than the width of cutting seam simultaneously, and the lead slider 402 upper end receives the spacing of skull and bone piece, is located the upside of skull and bone piece, and the lead slider 402 lower extreme inserts in the cutting seam inside simultaneously, and guide locking line 401 enters into the cutting seam, and lead slider 402 can lay locking line 401 gradually and get into the cutting seam inside when receiving traction mechanism to drive and produce the motion, through above structure, use locking line 401 and lead slider 402 can prevent that brain tissue from receiving the damage, simultaneously to the peripheral complex bone piece of cutting down on the skull, also can comparatively convenient centre gripping.
Wherein, as shown in fig. 7 and 8, two traction mechanisms are inserted inside two rotation holes 102 at the rear end of the mounting member 101 while the two traction mechanisms are rotatably connected with the mounting member 101; the lower end of the traction mechanism is provided with a storage structure; the bone slice is taken in through accomodating the structure to the both ends of guide structure, during the use, through rotating the traction mechanism of one side, can pull guide structure, make limit structure remove along the cutting seam, and make guide structure enter into inside the cutting seam, after guide structure follows home position to the end position, reverse rotation opposite side's traction mechanism, can make guide structure hug tightly the bone slice that cuts down, and then can take off bone slice from the skull, through above structure, for bone holder, vertical decurrent action when holding bone holder centre gripping, horizontal action when changing into guide structure hugging bone slice, can effectually prevent stabbing brain tissue, safer, guide structure is more for the contact point of bone slice simultaneously, after hugging bone slice, can make the fixed of bone slice more stable, effectually avoid bone slice drop, cause secondary injury to brain tissue.
Wherein, as shown in fig. 7 and 8, the traction mechanism comprises a traction part 3; the traction part 3 comprises a traction piece 301 and a wire box 302; the upper end of the traction piece 301 is fixedly connected with a handle for rotating the traction piece 301;
preferably, the receiving structure is embodied as a wire box 302; the lower end of the traction piece 301 is fixedly connected with a wire box 302, and the tail end of a locking wire 401 is accommodated in the wire box 302; the wire box 302 is used to receive the locking wire 401 while providing the movement of the wire slider 402 with the locking wire 401 that needs to be received and extended.
Wherein, as shown in fig. 2, a connecting plate 501 is fixedly connected to the right side of the mounting member 101; the right side of the connecting plate 501 is fixedly connected with a holding frame 502; through setting up portion of gripping 5, the experimenter of being convenient for holds this device.
Specific use and action of the embodiment: according to the invention, an experimenter needs to determine the distance and the penetration depth of two positioning structures according to the drill hole on the skull, then holds the device, penetrates the two positioning structures into the drill hole, cuts the guide structure into the drill hole at the initial position by adjusting the angle of the positioning structures, drives the guide structure to slide towards the end position along the track of the cut seam by rotating the traction mechanism at one side, distributes the guide structure into the cut seam, gradually tightens the guide structure around the bone piece by rotating the traction mechanism at the other side after the guide structure reaches the end position, and holds the bone piece tightly, and can stably and safely take out the bone piece after lifting the device.
Embodiment two:
after taking bones, a flexible sensor is implanted into the brain of the rat, and the specific steps are as follows:
A. completely removing the rat skull with forceps to expose the dura mater;
B. the mouse head is fixed in the stereotactic frame by the ear strip and the biting plate, so that the brain stability is ensured;
C. the actuator was attached to a mount in a stereotactic frame and moved using a micromanipulator, the circular flat tip (3 mm diameter) of the actuator was fixed in the center of the open skull region. Then adjusting the needle tip to an angle parallel to the surface of the impact part;
D. establishing a zero point by moving an actuator in the expansion model downward until the tip contacts the surface of the impact site;
E. clicking start to strike the injured part to reach a deformation depth of 5 mm;
F. implanting a sensor;
G. suturing the wound and rewarming.
The foregoing is merely exemplary embodiments of the present invention and is not intended to limit the scope of the invention, which is defined by the appended claims.
Claims (10)
1. A novel bone harvesting device, comprising:
the locking mechanism comprises a positioning structure and a guiding structure, wherein the two positioning structures are fixed in a drilled hole drilled before skull cutting and used for limiting the starting position and the ending position of the guiding structure, and the guiding structure moves from the positioning structure at the starting position to a gap between the skull and a bone fragment, and the positioning structure at the ending position stops moving;
the tail ends of the two traction mechanisms are respectively connected with the two ends of the guide structure, the guide structure can move in a gap between the skull and the bone fragments by adjusting the two traction mechanisms, and the guide structure can encircle the outer side of the bone fragments to hug the bone fragments;
the positioning structure comprises a guide part (2); the guide part (2) comprises a guide piece (201), a support piece (202) and a limiting piece (203); the two guide parts (2) are respectively inserted into the rotating hole (102) and the sliding hole (103) at the front end of the mounting piece (101); the lower end of the guide piece (201) is provided with threads for installing the limiting piece (203); a wire hole is formed in the lower end of the thread of the guide piece (201), and the wire hole is circular; screw holes are formed in the support piece (202); the supporting piece (202) is connected to the outer side of the thread of the guide piece (201) through a screw hole and is used for limiting the depth of the bottom of the guide piece (201) penetrating into the skull drill hole; the limiting piece (203) is internally provided with a through hole, and the limiting piece (203) is inserted into the guide groove (104); the limiting piece (203) is fixedly connected to the outer side of the left guide piece (201);
the middle part of the guide structure is fixedly connected with a limiting structure for limiting the position of the guide structure, and the guide structure comprises a locking part (4); the locking part (4) comprises a locking wire (401) and a lead slider (402); the locking wire (401) is a medical nylon wire, and the tail end of the locking wire (401) is spirally curled; the limiting structure is a lead slider (402), and the section of the lead slider (402) is of a T-shaped structure.
2. The novel bone extraction device according to claim 1, further comprising a mounting portion (1) for mounting the locking mechanism and the traction mechanism; the mounting piece (101) of the mounting part (1) is of an I-shaped structure, and rotary holes (102) are respectively formed in the left side and the right side of the rear end of the mounting piece (101) and the right side of the front end of the mounting piece.
3. The novel bone taking device according to claim 2, wherein a sliding hole (103) is formed on the left side of the front end of the mounting piece (101), and the sliding hole (103) is in a shape of a round rectangle; guide grooves (104) which are symmetrical in front and back are formed in the middle of the inner wall of the sliding hole (103) and are used for limiting and guiding one of the positioning structures.
4. A novel bone harvesting apparatus according to claim 3, wherein a first one of said positioning structures is inserted inside the rotation hole (102) and is rotatably connected to the mounting member (101); the other positioning structure is inserted into the sliding hole (103) and is in sliding connection with the mounting piece (101) and used for adjusting the distance between the two positioning structures so as to adapt to different-distance drilling holes on the skull.
5. The novel bone harvesting device according to claim 1, wherein the upper end of the guide member (201) is provided with a handle.
6. The novel bone harvesting device according to claim 1, wherein the support member (202) is of a basin-shaped configuration.
7. The novel bone taking device according to claim 1, wherein two ends of the lead slider (402) are respectively connected with the head ends of two locking wires (401).
8. The novel bone extraction device according to claim 2, wherein two of said traction mechanisms are inserted inside two rotation holes (102) at the rear end of the mounting member (101) while the two traction mechanisms are rotatably connected to the mounting member (101); the lower extreme of traction mechanism sets up the storage structure.
9. The novel bone extraction device according to claim 7, characterized in that the traction mechanism comprises a traction part (3); the traction part (3) comprises a traction piece (301) and a wire box (302); the upper end of the traction piece (301) is fixedly connected with a handle for rotating the traction piece (301);
the storage structure of the traction mechanism is a wire box (302); the lower end of the traction piece (301) is fixedly connected with a wire box (302), and the tail end of a locking wire (401) is accommodated in the wire box (302).
10. The novel bone extraction device according to claim 2, characterized in that the right side of the mounting member (101) is fixedly connected with a connecting plate (501); the right side of the connecting plate (501) is fixedly connected with a holding frame (502).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310674167.5A CN116392285B (en) | 2023-06-08 | 2023-06-08 | Novel bone taking device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310674167.5A CN116392285B (en) | 2023-06-08 | 2023-06-08 | Novel bone taking device |
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| CN218220351U (en) * | 2022-08-26 | 2023-01-06 | 丽水学院 | Autogenous bone fragment centre gripping pincers |
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| CN116392285A (en) | 2023-07-07 |
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