CN116391870A - Food composition for quickly supplementing physical ability and repairing muscle injury after exercise - Google Patents

Food composition for quickly supplementing physical ability and repairing muscle injury after exercise Download PDF

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CN116391870A
CN116391870A CN202310264063.7A CN202310264063A CN116391870A CN 116391870 A CN116391870 A CN 116391870A CN 202310264063 A CN202310264063 A CN 202310264063A CN 116391870 A CN116391870 A CN 116391870A
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parts
exercise
mice
formula
vitamin
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扈洪波
唐佳琪
曹丽行
赵冲
尹淑涛
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention aims to provide a food nutrition formula for quickly supplementing physical ability and repairing muscle injury, which comprises the following raw materials in parts by weight: 150 parts of glucose, 100 parts of fructose, 27 parts of collagen peptide, 19 parts of glutamine, 22 parts of sodium chloride, 11 parts of potassium citrate, 1 part of taurine, 1 part of glycine, 0.5 part of beta-alanine, 0.3 part of vitamin C and 0.01 part of vitamin B. The formula has the effects of remarkably enhancing physical performance, relieving sports injury and restoring glycogen storage in vivo. The invention has the effects of promoting the recovery of the physical ability after exercise and the prescription after short-term administration, improving the grabbing power of mice, reducing the levels of creatine kinase and lactate dehydrogenase in serum of the mice, relieving the injury caused by exercise and recovering glycogen stores of the mice after immediate administration after exercise. The invention provides a new formula for developing sports health-care food and has great application value.

Description

Food composition for quickly supplementing physical ability and repairing muscle injury after exercise
Technical Field
The invention relates to the field of health-care food, in particular to a food nutrition formula for promoting rapid physical stamina supplement and muscle injury repair after exercise.
Background
Physical stamina is the basic athletic ability that people show through the motion quality such as strength, speed, endurance, harmony, flexibility, sensitivity in the motion process, possess good athletic stamina and participate in each item leisure and competitive sport, enjoy the most basic condition of motion enjoyment. Along with the improvement of national living standard, the body-building concept is continuously extended into the common crowd, and high-intensity work, acute high load or unaccustomed exercise can consume a large amount of physical energy, so that body electrolyte is lost, body fluid balance is destroyed, muscle oxidative damage is caused, normal activities of human bodies are influenced, and the health of the human bodies is threatened. The energy, protein and electrolyte which are consumed are needed to be timely supplemented after exercise, so that physical energy recovery can be assisted and muscle protein synthesis can be accelerated. When people are in physical fitness, athletes with high exercise amount, rescue workers with high working strength and the like, the requirement for the quick recovery of physical ability is urgent, so that the method has important significance for accelerating the recovery of physical ability after the exercise of human body by developing food formulas.
The body can consume a large amount of physical energy in the exercise process, and the glycogen stores in the body can be exhausted after long-time exercise, so that the body is converted from aerobic sugar metabolism to fat combustion, further muscle oxidative damage and lactic acid accumulation are caused, and fatigue is generated. Therefore, a food composition capable of promoting glycogen recovery, regulating body fluid balance, and repairing oxidative damage is very important. The invention aims to provide a food formula which has wide raw material sources, is suitable for the parents of the price and has wide applicability, and can quickly supplement physical stamina and repair muscle injury.
Disclosure of Invention
The invention aims to provide a food nutrition formula for quickly supplementing physical ability and repairing muscle damage.
The invention provides a food formula for quickly supplementing physical ability and repairing muscle injury, which comprises the following components in parts by weight: 100-200 parts of glucose, 50-150 parts of fructose, 25-30 parts of collagen peptide, 17-22 parts of glutamine, 20-25 parts of sodium chloride, 9-13 parts of potassium citrate, 1 part of taurine, 1 part of glycine, 0.5 part of beta-alanine, 0.3 part of vitamin C and 0.01 part of vitamin B.
Glucose, which is the most rapidly absorbed monosaccharide by the body, enters the systemic circulation mainly passively from the visceral area after intestinal absorption, and is the most important energy supply substance for the human body.
Fructose, the monosaccharide with the highest sweetness, can endow the beverage with fresh flavor, improve unpleasant smell brought by glutamine and vitamins, promote gluconeogenesis and liver glycogenosis at the same time, and the literature shows that glucose and fructose can be taken simultaneously to relieve gastrointestinal burden and avoid diarrhea.
Collagen peptide is a small molecular peptide which is easier to absorb and is prepared by collagen hydrolysis, and the collagen is a main component of muscle cells of a human body, and has the potential effects of properly supplementing the collagen to repair muscle tissues and improve athletic performance.
Glutamine, one of the essential amino acids of the human body, participates in protein synthesis, and can be timely supplemented after exercise to effectively prevent muscle protein decomposition, maintain amino acid balance, promote muscle growth and relieve muscle soreness.
Sodium chloride and human body electrolyte can supplement sodium ions which are lost in a large amount along with perspiration after exercise, and promote the recovery of body fluid balance.
The potassium citrate and the organic acid potassium salt are more favorable for the absorption of organisms than the inorganic acid potassium salt, and can quickly supplement potassium ions lost after exercise and restore the body fluid balance.
Taurine, which is rich in amino acids in human muscle and viscera, not only participates in metabolism of organism, but also has functions of maintaining calcium steady state inside and outside cells, regulating osmotic pressure, etc., and also has functions of scavenging free radicals and protecting cardiac muscle.
Glycine not only participates in protein synthesis, and can be used for repairing muscle injury and improving athletic performance, but also can be used as synthesis raw material of neurotransmitter, and has effects of relieving fatigue and anxiety.
Beta-alanine, a non-protein amino acid, is catalyzed in vivo by carnosine synthase along with histidine to produce carnosine. As a sports nutrition supplement which is widely paid attention to at home and abroad at present, the beta-alanine has the effects of promoting energy metabolism, resisting oxidization, relieving muscle injury after sports and the like.
Vitamin C has good antioxidant function, is helpful for reducing inflammation and muscle soreness, can effectively remove free radicals generated by athletes in sports, prevent and slow down sports free radical injury, and has potential effects of relieving sports fatigue and improving sports endurance.
Vitamin B1 participates in energy production during exercise and plays an important role in sugar metabolism, is a coenzyme component of pyruvate dehydrogenase, and when a human body lacks vitamin B1, the vitamin B1 can directly influence aerobic metabolism and energy supply of skeletal muscle, thereby causing muscle contraction weakness and endurance deterioration.
The functional components have the characteristics of crossing action paths for promoting physical ability recovery after exercise, and the combination of the functional components is more beneficial to promoting physical ability recovery after body exercise, and the action paths are clear, safe and efficient.
The food formula for promoting physical recovery after exercise is prepared into a light yellow beverage by mixing the components according to the specified mass part ratio and completely dissolving the components in purified water.
The food for promoting the physical ability recovery after exercise of the invention is taken immediately after each time of exhaustion exercise.
The invention is carried out in a mode of 1 time per day in dosage, and each time, 1200-1250mg/kg bw.
Experiments prove that the Formula for promoting the physical recovery after exercise has the effects of restoring physical strength, promoting the synthesis of myoglycogen, reducing the levels of creatine kinase and lactate dehydrogenase in serum and relieving the potential effect of exercise injury, compared with a Control group (Control group) for supplementing clear water after strenuous exercise, the creatine kinase level in serum of a mouse supplemented with the Formula group (Formula group) is reduced by 43.2 percent (P < 0.001) after 24 hours, the lactate dehydrogenase level in serum is reduced by 13.0 percent (P < 0.01), and the experimental results are shown in figures 3 and 4. The soleus muscle glycogen content of mice in the formula group was increased by 91.1% (P < 0.05) and restored to a level close to that of the resting group (p=0.51) compared to the control group supplemented with clear water.
The application of the food formula in promoting physical recovery after exercise also belongs to the protection scope of the invention.
The invention designs the formula scientifically and reasonably according to the existing mechanism of sports injury and the like, and the components in the formula are food-borne functional components which promote the recovery of the sports after one or more ways are shown based on the current research, and the food-borne functional components comprise 11 functional components of glucose, fructose, collagen peptide, glutamine, sodium chloride, potassium citrate, taurine, glycine, beta-alanine, vitamin C and vitamin B1, and the formula has the characteristics of naturalness, safety, high efficiency, no toxic or side effect, clear action way and the like. The food formula for promoting physical ability recovery after exercise has an effect after being taken for a short period, can improve exercise capacity, restore glycogen storage and reduce the levels of creatine kinase and lactate dehydrogenase in serum of mice after being taken immediately after each exercise, and effectively relieves exercise injury.
Drawings
Fig. 1 shows the finished sports drink.
Figure 2 shows the effect of the supplemental formulation on the mouse grip immediately after 7 consecutive days of exercise.
Figure 3 shows the effect of supplementation of the formulation on creatine kinase in mouse serum immediately after 7 consecutive days of exercise.
FIG. 4 shows the effect of supplementation of the formulation on lactate dehydrogenase in mouse serum immediately after 7 consecutive days of exercise.
Figure 5 shows the effect of supplementation of formulation on myoglycogen in mice soleus muscle immediately after 7 consecutive days of exercise.
+ p<0.05， ++ p<0.01， +++ p<0.001, vs. sedary group;
* p <0.05, < p <0.01, < p <0.001, vs. Control group (Control group).
Detailed Description
The present invention will be described with reference to the following specific examples, but the present invention is not limited thereto.
The experimental methods used in the following examples are all conventional methods unless otherwise specified; the reagents, materials, etc. used in the examples described below are commercially available unless otherwise specified.
Example 1
100-200 parts of glucose, 50-150 parts of fructose, 25-30 parts of collagen peptide, 17-22 parts of glutamine, 20-25 parts of sodium chloride, 9-13 parts of potassium citrate, 1 part of taurine, 1 part of glycine, 0.5 part of beta-alanine, 0.3 part of vitamin C and 0.01 part of vitamin B are weighed according to a proportion, 52-56g is dissolved in 500mL of purified water, and the components are uniformly mixed.
And (3) canning the beverage, sterilizing for 10min under 500MPa, and obtaining the finished sports beverage (figure 1).
Example 2
A food nutrition formulation for promoting physical recovery after exercise is provided. The composition comprises the following components: 100-200 parts of glucose, 50-150 parts of fructose, 25-30 parts of collagen peptide, 17-22 parts of glutamine, 20-25 parts of sodium chloride, 9-13 parts of potassium citrate, 1 part of taurine, 1 part of glycine, 0.5 part of beta-alanine, 0.3 part of vitamin C and 0.01 part of vitamin B
The test method comprises the following steps: male C57 BL/6N mice, 24, 6-8 weeks old, all randomly divided into resting (sedary group), control group, formulation group (formulation group), 8 per group. The exercise group and the formula group were run on a downhill run for 60 min for 7 consecutive days, immediately after each exercise the formula group was irrigated with 2962 mg/kg bw of formula compound and the exercise group was irrigated with 15mL/kg bw of purified water. The resting group was perfused with 15mL/kg bw of purified water daily at the corresponding time. After the last lavage 24h, a grip test was performed.
Motion model: experimental animal running table. Slope-16 degrees, initial speed 10 m/min, adding 4 m/min every 5 min until 18 m/min, and keeping speed 16 m/min for 50 min.
Grip strength test: the bottom of the tail was grasped and then lowered vertically onto the rod of the grab meter. The mice were pulled slightly backwards while the two paws (forelimbs) of the mice gripped the rod, triggered "reverse pull", the grip was recorded in newtons (N), repeated 4 times, 90s apart each time, and the average of the last three times was taken. Mice were trained to be familiar with this procedure two days prior to exercise.
The experimental results (fig. 2) show that the food formula for promoting physical recovery after exercise has the effect of recovering the physical strength of the mice after exercise, and the holding power of the mice is improved by 10.5% compared with that of the exercise control group (p < 0.05).
Example 3
0039. A food nutrition formulation for promoting physical recovery after exercise is provided. The composition comprises the following components: 100-200 parts of glucose, 50-150 parts of fructose, 25-30 parts of collagen peptide, 17-22 parts of glutamine, 20-25 parts of sodium chloride, 9-13 parts of potassium citrate, 1 part of taurine, 1 part of glycine, 0.5 part of beta-alanine, 0.3 part of vitamin C and 0.01 part of vitamin B
The test method comprises the following steps: male C57 BL/6N mice, 24, 6-8 weeks old, all randomly divided into resting (sedary group), control group, formulation group (formulation group), 8 per group. The exercise group and the formula group were run on a downhill run for 60 min for 7 consecutive days, immediately after each exercise the formula group was irrigated with 2962 mg/kg bw of formula compound and the exercise group was irrigated with 15mL/kg bw of purified water. The resting group was perfused with 15mL/kg bw of purified water daily at the corresponding time. After the last lavage 24h, mice were sacrificed for serum, soleus muscle and liver.
Motion model: experimental animal running table. Slope-16 degrees, initial speed 10 m/min, adding 4 m/min every 5 min until 18 m/min, and keeping speed 16 m/min for 50 min.
Experimental results (fig. 3) demonstrate that this post-exercise performance recovery food formula supplementation has the potential to reduce motor impairment in mice in downhill motor models, with 43.2% lower creatine kinase levels in the serum of the mice compared to the motor control group (p < 0.001).
Experimental results (fig. 4) demonstrate that the post-exercise performance recovery food formula supplementation has the potential to reduce exercise damage in mice in downhill exercise models, with 13.0% lower lactate dehydrogenase levels in the serum of the mice compared to the exercise control group (p < 0.01).
Experimental results (fig. 5) demonstrate that the post exercise physical recovery food formula supplementation has the effect of recovering muscle glycogen consumed in mice in downhill exercise models, with a 91.1% increase in muscle glycogen levels in the mice soleus muscle (p < 0.05) compared to the exercise control group, and approaching resting levels (p=0.51).
Experiments prove that the formula for promoting the recovery of physical fitness after exercise disclosed by the invention has the potential effects of recovering physical strength, promoting the synthesis of myoglycogen, reducing the levels of creatine kinase and lactate dehydrogenase in serum and relieving exercise injury after short-term supplementation. Taking the gripping force as an evaluation standard, the invention has the effect of quickly recovering physical stamina after exercise (figure 2). As can be seen from fig. 3 and 4, compared with the Control group (Control group) supplemented with clear water after severe exercise, the creatine kinase level in serum of mice supplemented with Formula group (Formula group) is reduced by 43.2% (p < 0.001), and the lactate dehydrogenase level in serum is reduced by 13.0% (p < 0.01), which proves that the invention can rapidly remove metabolic waste in body fluid after exercise and reduce body injury. As can be seen from fig. 5, compared with the control group supplemented with clear water, the soleus muscle glycogen content of the mice in the formula group was increased by 91.1% (p < 0.05) and recovered to a level close to that of the resting group (p=0.51), demonstrating that the present invention can promote the synthesis of muscle glycogen after exercise, contributing to physical recovery.

Claims (4)

1. Use of a food composition for promoting physical recovery after exercise, comprising by weight: 150 parts of glucose, 100 parts of fructose, 27 parts of collagen peptide, 19 parts of glutamine, 22 parts of sodium chloride, 11 parts of potassium citrate, 1 part of taurine, 1 part of glycine, 0.5 part of beta-alanine, 0.3 part of vitamin C and 0.01 part of vitamin B.
2. The use according to claim 1, characterized in that: the food formula can weigh 52-56g of the composition according to mass, and completely dissolve in 500mL of purified water to prepare a pale yellow sports drink.
3. The method according to claim 2, characterized in that: the sports beverage is prepared by adopting an ultrahigh pressure sterilization mode.
4. A method for quickly restoring physical ability after exercise, which is characterized in that: immediately after exercise, the beverage prepared according to the method of claim 2 is taken 1 time a day, 1200-1250mg/kg bw.
CN202310264063.7A 2023-03-18 2023-03-18 Food composition for quickly supplementing physical ability and repairing muscle injury after exercise Pending CN116391870A (en)

Priority Applications (1)

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CN202310264063.7A CN116391870A (en) 2023-03-18 2023-03-18 Food composition for quickly supplementing physical ability and repairing muscle injury after exercise

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310264063.7A CN116391870A (en) 2023-03-18 2023-03-18 Food composition for quickly supplementing physical ability and repairing muscle injury after exercise

Publications (1)

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CN116391870A true CN116391870A (en) 2023-07-07

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