CN116370836A - Method and device for improving eyesight by low-energy red light self-adaptive radiation type polarized irradiation - Google Patents
Method and device for improving eyesight by low-energy red light self-adaptive radiation type polarized irradiation Download PDFInfo
- Publication number
- CN116370836A CN116370836A CN202310181361.XA CN202310181361A CN116370836A CN 116370836 A CN116370836 A CN 116370836A CN 202310181361 A CN202310181361 A CN 202310181361A CN 116370836 A CN116370836 A CN 116370836A
- Authority
- CN
- China
- Prior art keywords
- linear
- light
- red light
- polarized light
- fundus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000005855 radiation Effects 0.000 title claims abstract description 41
- 238000000034 method Methods 0.000 title claims abstract description 14
- 230000004438 eyesight Effects 0.000 title description 9
- 230000010287 polarization Effects 0.000 claims abstract description 41
- 238000003384 imaging method Methods 0.000 claims abstract description 26
- 210000001525 retina Anatomy 0.000 claims abstract description 15
- 239000000835 fiber Substances 0.000 claims abstract description 12
- 230000004377 improving vision Effects 0.000 claims abstract description 6
- 238000013519 translation Methods 0.000 claims description 10
- 241000519995 Stachys sylvatica Species 0.000 claims description 7
- 230000003044 adaptive effect Effects 0.000 claims description 4
- 238000012545 processing Methods 0.000 claims description 4
- 230000008859 change Effects 0.000 claims description 3
- 238000005286 illumination Methods 0.000 claims description 2
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 238000001514 detection method Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 8
- 102000008186 Collagen Human genes 0.000 abstract description 7
- 108010035532 Collagen Proteins 0.000 abstract description 7
- 229920001436 collagen Polymers 0.000 abstract description 7
- 230000000638 stimulation Effects 0.000 abstract description 2
- 239000002131 composite material Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 8
- 238000010586 diagram Methods 0.000 description 6
- 210000001508 eye Anatomy 0.000 description 5
- 210000001328 optic nerve Anatomy 0.000 description 4
- 210000001747 pupil Anatomy 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 101100327165 Arabidopsis thaliana CCD8 gene Proteins 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000005252 bulbus oculi Anatomy 0.000 description 2
- 230000001678 irradiating effect Effects 0.000 description 2
- 238000001126 phototherapy Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 208000002177 Cataract Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 208000030533 eye disease Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000002189 macula lutea Anatomy 0.000 description 1
- 208000002780 macular degeneration Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000002438 mitochondrial effect Effects 0.000 description 1
- 208000001491 myopia Diseases 0.000 description 1
- 230000004379 myopia Effects 0.000 description 1
- 210000004126 nerve fiber Anatomy 0.000 description 1
- 210000004498 neuroglial cell Anatomy 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000004382 visual function Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0664—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/073—Radiation therapy using light using polarised light
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The invention relates to a method and a device for improving vision by adjusting irradiation fundus with low-energy red light self-adaptive polarization. The method includes that incident light is parallel red light polarized light beam, the light beam is generated by natural light through a composite linear polarizing plate, emergent light of radiation type linear polarized light is formed, and a retina area is irradiated by taking a video disc as a center, so that each linear polarization direction diverges along retina collagen fibers. Because of individual difference, the invention introduces a video disc imaging positioning system to adjust the center position of the radial polarized light beam so that the radial polarized light beam is positioned at the center of the video disc, thereby enabling the divergent radiation direction of the linear polarized light to be attached to the direction of the retina collagen fiber cells and achieving better stimulation irradiation treatment effect.
Description
Technical Field
The invention relates to the field of restoration and treatment of visual functions, in particular to a method for adjusting and irradiating fundus by adopting low-energy red light self-adaptive radiation polarization and improving vision and a corresponding device thereof.
Background
The vision improvement technology has become a hot topic of the current medical research, wherein the vision improvement by low-energy infrared irradiation on the fundus is an effective treatment method, which can improve the symptoms of eye diseases such as vision and blurred vision, and has an important role in the treatment of myopia at present. Research shows that the low-energy red light can improve the metabolism of retina cells, stimulate cone cells, improve the oxygen carrying capacity of red blood cells, strengthen the fixation function of the center of macula lutea, promote the regeneration of retina cells, and improve vision. Currently, low energy red light therapy has been widely used to treat ocular fundus lesions such as macular degeneration, glaucoma, cataracts, and the like.
The invention provides a therapy and a device for introducing low-energy red light with a radiation linear polarization state and irradiating retina with a video disc as a center according to a red light therapy principle so as to improve vision more effectively. Polarized red light is a special red light in which the electric field vector in electromagnetic waves is vibrated in a specific direction. The polarized red light irradiation increases the collagen content (Silva. D.F 2006,Journal of Biomedical Optics) compared with the natural light stimulation, thereby improving the elasticity and toughness of the eyeball. Especially, the laser irradiation can also improve the strength of the cornea collagen fiber (S.E. Avetisov 2013,Journal of Biomedical Optics), and when the polarization direction is irradiated along the fiber direction, the irradiation is more beneficial to stimulating the activity of fiber cells (Ando 2013,Journal of Biomedical Optics), promoting the functions of cone rod cells, glial cells, polar cells and the like (Hulyarso, 2015Medical Informatics and Engineering), and can remarkably enhance the activity of retina, thereby accelerating the repair of damaged retina. Because the nerve fiber diverges with the optic disc (disk) as the center, the invention adopts the radiation type linearly polarized light red light to better ensure that the polarization direction is attached to the trend of the optic nerve fiber, thereby ensuring the irradiation intensity and the treatment effect. Meanwhile, due to individual difference, the linear polarization imaging technology is used for positioning, and the central position of the radiation type linear polarized light beam is adjusted, so that the divergent radiation direction of the linear polarized light is attached to the direction of the retina collagen fiber cells, and the better effect of stimulating irradiation treatment is achieved.
Disclosure of Invention
A method and device for improving vision by low-energy red light self-adaptive polarization state adjustment irradiation of fundus is characterized in that red light is modulated to have radiation type linear polarization characteristic while parallel red light beams irradiate eyes for treatment. The linear polarization imaging technology is used for imaging and positioning the eyeground retina to position the optic disc, and the center position of the radial polarization parallel light beam entering the pupil is adjusted, so that the radial polarization parallel light beam irradiates along the direction in which optic nerve collagen fibers around the optic disc diverge more effectively, stimulates deeper eyeground tissues, and has better vision improvement effect.
The device of the invention comprises an emission source which is a red LED or a red laser source; the radiation type linear polarization device is formed by splicing linear polarization fan-shaped plates with the same radius and small radian, and the linear polarization directions of the fan-shaped plates are all along the radial direction, so that a radiation type linear polarized light beam is generated; a rotatable wheel having a linear polarizer and a light intensity attenuator, the rotatable wheel being operable to switch between the conversion of said radiation into single-direction linear polarization and radiation by rotation; the fundus imaging system consists of a linear polaroid, a two-dimensional imaging detector and a processing unit; a two-dimensional translation system for enabling the radial linear polarization polarizer, the rotatable wheel disc and the fundus imaging system to translate simultaneously, wherein the two-dimensional translation system can be controlled by two micro-motor units; a light intensity regulator for controlling light intensity is composed of a gradually-changed light intensity attenuation sheet.
The method of the invention comprises the following steps:
(1) The system receives a signal for starting to work, and the red light source, the rotatable wheel disc, the fundus imaging system and the light intensity regulator start to be started;
(2) As shown in fig. 1, a red light source 1 emits a parallel light beam 2, and a radiation type parallel red light having linearly polarized light in all directions on a cross section is formed by a radiation type linear polarization device 3. The polarized parallel red light travels in a direction with a small angle with the central axis 4 and is downwards obliquely incident, and the oblique incidence is caused by that the center of the retina optic disc is positioned below the central line of the eye axis in physiology;
(3) The rotatable wheel disc 5 adjusts the linear polarizing plate 6 to change the radiation linear polarized light into single-direction linear polarized light to pass through;
(4) The linear polaroid 7 and the two-dimensional area array detector 8 of the fundus imaging system and the red light source are symmetrically and obliquely incident and received about the center of an eye axis, and single linear polarized parallel red light generated in the steps (2) and (3) is used as an incident light source, and reflected light returned on the retina passes through the linear polaroid 8 of the imaging system. The linear polarizer 8 is perpendicular to the vibration direction of the polarizer 6 in step (3), and finally a fundus image is formed on the two-dimensional probe 9. Since the optic disc is isotropic, other areas are anisotropic, and an white spot appears on the image;
(5) According to the detected image in the step (4), the whole equipment is translated by utilizing a two-dimensional translation system 10, the equipment is adaptively moved, so that white spots are moved to the center of the image, namely, the center of a light beam just irradiates the video disc 11;
(6) The rotatable wheel is tuned to the light intensity attenuator 6 to allow the radiation to pass linearly polarized light. According to the adjustment of the steps (4) and (5), the center of the linearly polarized light is well irradiated on the video disc 11, and the direction of the linearly polarized light is attached to the direction of peripheral visual fibers;
(7) The eyes were irradiated for 3 minutes through the above steps (1) - (6), and the treatment was ended once and twice daily.
Compared with the prior art, the invention has the beneficial effects that:
(1) The invention adopts low-energy red light with specific polarization state, and can not cause obvious injury or uncomfortable feeling to eyes. The characteristic is that the radial linear polarization treatment is adopted for entering the pupil, the divergent linear polarization direction taking the optic disc as the center is better attached to the fiber direction of the optic nerve cell, the tissue of the fundus can be stimulated more effectively, and the mitochondrial activity and the growth of the nerve cell are improved. The method is a non-invasive treatment mode, which not only ensures the irradiation intensity of red light, but also improves the treatment effect.
(2) The invention introduces a retina optic disc imaging positioning system, obtains the relative position of the optic disc on the image by using a linear polarization orthogonal imaging system, and can adaptively adjust the position of an incident plane by incident light so that the radiation polarization center of a light beam is positioned near the optic disc. Thus, the direction of the incident radiation type linear polarized light and the direction of optic nerve collagen fibers around the optic disc can be well matched and overlapped, the accurate positioning and adjustment of the radiation type linear polarized light beam are realized, the accuracy and the effectiveness of treatment are improved, and the better treatment effect is realized.
Drawings
FIG. 1 is a schematic diagram of a system arrangement of the present invention;
FIG. 2 is a schematic diagram of the structure of a radial linear polarizer of the present invention;
FIG. 3 is a schematic diagram of an embodiment of the present invention;
fig. 4 is a flow chart of the steps of an embodiment of the present invention.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
FIG. 1 is a schematic diagram of the system device structure of the present invention, which comprises the following devices: the red light source 1 is a red light LED or a laser source, and emits a parallel light beam 2. The radiation type linear polarization device 3 is formed by splicing linear polarization fan-shaped plates with the same radius and small radian, and the linear polarization directions of the fan-shaped plates are all along the radial direction, so that a radiation type linear polarized light beam is generated. The device also comprises a central axis 4, a rotatable wheel disc 5. The polarized parallel light beam will be irradiated perpendicularly to the ocular cells 5 through the light guide tube.
Fig. 2 is a schematic structural diagram of a radiation type linear polarizer of the present invention, in which a radiation type linear polarizer 1 is formed by splicing linear polarizing fan-shaped plates 2 with small radians of the same radius, and the linear polarization directions of the fan-shaped plates are all along the radial direction, so as to generate a radiation type linear polarized light beam.
An embodiment of the present invention will be further described with reference to the accompanying drawings.
Fig. 3 is a schematic diagram of an embodiment of the present invention, specifically an example of a low-energy red light adaptive radiation type fundus-polarized illumination vision improving device. The device comprises five parts, wherein a 630nm laser light source 1 and a beam expander 2 are adopted as a light source part, a polarization adjusting device consists of a radiation type linear polaroid 3 and a rotatable wheel disc 4 (consists of a linear polaroid 5 and a light intensity adjuster 6 which are gradual change type light intensity attenuation sheets), a fundus imaging system consists of a linear polaroid 7 and an area array CCD (comprising an imaging processing unit) 8, and a two-dimensional translation system consists of two one-dimensional translation tables.
FIG. 4 is a flowchart showing the steps of the embodiment of the present invention, which comprises the following specific implementation steps:
(1) The system receives signals to start working, a 630nm laser light source 1 emits 5mW laser, a parallel beam with the section diameter of 10mm is generated through a laser beam expander 2, and meanwhile, a rotatable wheel disc 4, a fundus imaging system linear bias sheet 7, an area array CCD8 and a power supply of a light intensity regulator 6 start to be started.
(2) The light beam formed in the step (1) is downwards obliquely incident in a certain small angle with the upper part of the central axis 10 of the eyeball by 20 degrees, so that the light beam can better approach the center of the optic disc on the retina at the correct position;
(3) The light beam in the step (2) passes through a radiation type linear polaroid sheet 3 in a polarization regulating device to form radiation type polarized parallel red light with linearly polarized light in all directions on the section;
(4) Passing the radiation type polarized parallel red light in the step (3) through a rotatable wheel disc 4 in a polarization adjustment device, and rotating the wheel disc to a linear polaroid 5 through a rotation device, wherein the vibration direction of the linear polaroid is a horizontal direction;
(5) The fundus imaging system is arranged below the central axis of the ocular axis, the arrangement angle and the light source are in an axisymmetric mode, and the linear polaroid 7 in the fundus imaging system is rotated to a vertical angle so as to form an included angle of 90 degrees with the linear polaroid 3 in the step (4);
(6) Forming an imaging light path by the incident light in the step (4) and the reflected light in the step (5), forming a fundus image on the area array CCD8, forming an white spot at the image due to isotropy of the optic disc and anisotropy of other areas,
(7) The white spot contrast in the image of the step (6) is the lowest, and the processing unit is used for calculating the central position coordinates of the white spot;
(8) Moving the two-dimensional translation device 9 reversely according to the coordinate value of the step (7) to enable the white spot to be positioned in the center of the image, and completing the positioning of the optical beam center to the video disc
(9) Rotating the rotatable wheel disc 4 in the polarization adjustment device in the step (4) to the light intensity attenuator 6 through the rotation device, so that the radiation type linearly polarized light beam can pass through;
(10) The 10mm cross-section parallel polarized red light is normally incident into the pupil, completely covering the pupil area.
(11) After 3 minutes of irradiation in the steps (1) - (5), the treatment is finished once and twice a day.
Claims (9)
1. The device for improving vision by adjusting irradiation fundus of low-energy red light adaptive polarization state is characterized by comprising an emission source which is a red light LED or a red light laser source; a radial linear polarization polarizer; a rotatable wheel; a fundus imaging system; a two-dimensional translation system; a light intensity regulator for controlling light intensity is composed of a gradually-changed light intensity attenuation sheet.
2. The radiation type linear polarization device according to claim 1, wherein the device is formed by splicing fan-shaped linear polarizers with small radian of same radius, and the linear polarization directions of the fan-shaped polarizers are all along radial direction, so as to generate radiation type linear polarized light beams.
3. A rotatable wheel according to claim 1 having a linear polarizer and light intensity attenuator thereon operative to switch between converting said radiation into single direction linear polarized light and radiation-type linear polarized light by rotation.
4. The fundus imaging system according to claim 1, comprising a linear polarizer, a two-dimensional imaging detector and a processing unit.
5. The two-dimensional translation system according to claim 1, wherein said radial linear polarization polarizer, said rotatable wheel and said fundus imaging system are simultaneously translatable.
6. A method for improving vision by illuminating fundus with low energy red light adaptive polarization adjustment, said method comprising the steps of:
(1) The system starts to work, and a red light source, a rotatable wheel disc, a fundus imaging system and a light intensity regulator are started;
(2) The red light source emits parallel light beams, and the light beams pass through the radiation type linear polarization device;
(3) The rotary wheel disc can be used for adjusting the linear polarizing plate to change the radiation linear polarized light into single-direction linear polarized light to pass through;
(4) The fundus imaging system receives the single linearly polarized parallel red light generated in the steps (2) and (3) as an incident light source and forms a fundus image;
(5) Translating the whole device by using a two-dimensional translation system according to the detection image in the step (4);
(6) The rotary wheel disc adjusts the light intensity attenuation sheet to enable the radiation linear polarized light to pass through, and according to the adjustment of the steps (4) and (5), the center of the radiation linear polarized light well irradiates the optic disc, and the direction of the linear polarized light is attached to the direction of peripheral optic fibers.
7. The method according to claim 6, wherein the radiation type linear polarization polarizing device in the step (2) forms radiation type parallel red light with linearly polarized light in all directions on a cross section, and the polarized parallel red light forms an included angle with a central axis by a certain small angle and is obliquely incident downwards.
8. The method according to claim 6, wherein in the step (4), the linear polarizer and the two-dimensional area array detector of the fundus imaging system are symmetrical to the red light source about the center of the eye axis, the single linear polarization parallel red light incident light source generated in the oblique incidence receiving steps (2) and (3) is used, the reflected light returned on the retina passes through the linear polarizer of the imaging system, the linear polarizer is perpendicular to the vibration direction of the polarizer in the step (3), and the fundus image is finally formed on the two-dimensional detector.
9. The method for improving vision by adjusting illumination fundus with low-energy red light adaptive polarization according to claim 6, wherein the detected image in step (5) is translated through a two-dimensional translation system to adaptively move the device so that white spots are moved to the center of the image, i.e. the center of the light beam is just illuminated on the optic disc.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310181361.XA CN116370836A (en) | 2023-02-27 | 2023-02-27 | Method and device for improving eyesight by low-energy red light self-adaptive radiation type polarized irradiation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202310181361.XA CN116370836A (en) | 2023-02-27 | 2023-02-27 | Method and device for improving eyesight by low-energy red light self-adaptive radiation type polarized irradiation |
Publications (1)
Publication Number | Publication Date |
---|---|
CN116370836A true CN116370836A (en) | 2023-07-04 |
Family
ID=86970216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310181361.XA Pending CN116370836A (en) | 2023-02-27 | 2023-02-27 | Method and device for improving eyesight by low-energy red light self-adaptive radiation type polarized irradiation |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN116370836A (en) |
-
2023
- 2023-02-27 CN CN202310181361.XA patent/CN116370836A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4836203A (en) | Device for therapeutical irradiation of organic tissue by laser radiation | |
US6186628B1 (en) | Scanning laser ophthalmoscope for selective therapeutic laser | |
CN109199689B (en) | Cornea treatment device based on adjustable optical element group and solution dripping absorption device | |
US6494878B1 (en) | System and method for accurate optical treatment of an eye's fundus | |
US20180280196A1 (en) | System for neuroprotective therapy for glaucoma | |
US20100290007A1 (en) | Electronic ophthalmoscope for selective retinal photodisruption of the photoreceptor mosaic | |
JPS612851A (en) | Apparatus and method for surgically removing turbid crystal tissue from eyeball in non-incisive manner | |
JPH06505906A (en) | Contact probe for laser cyclophotocoagulation | |
KR20130111932A (en) | Method and apparatus for treatment of ocular tissue using combined modalities | |
JPH10503940A (en) | Eye movement detection method and system | |
JPH08503625A (en) | Method and apparatus for laser heated cornea formation | |
TW200916081A (en) | A system for laser photoablation within a lens | |
US20240122782A1 (en) | Vision training device and vision training instrument cross-reference to related applications | |
CN102429767B (en) | Laser cornea hot forming surgery system | |
CN208741772U (en) | Ophtalmic treatments instrument | |
JP2021534905A (en) | Methods and systems for large spot retinal laser treatment | |
CN1957867A (en) | Intravital surgery system for scanning type laser operation of hot forming cornea | |
CN105944234A (en) | Semiconductor laser rehabilitation instrument based on three-wavelength laser | |
CN116370836A (en) | Method and device for improving eyesight by low-energy red light self-adaptive radiation type polarized irradiation | |
CN112137849A (en) | Bionic vision training instrument capable of achieving double light supplement for back pole of eye ground and peripheral vision of eye ground | |
CN114206436A (en) | Selective laser stimulation of corneal stem cells | |
CN115253090A (en) | Photodynamic therapy equipment at somatic cell level | |
CN205626738U (en) | Semiconductor laser instrument based on three wavelength laser | |
CN111407507B (en) | Eye tissue cutting device | |
CN108309559A (en) | Induced retinal generates and discharges dopamine and activate the method and ophtalmic treatments instrument of dopamine receptor D1 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
CB02 | Change of applicant information |
Address after: Room 517, No. 1348 Xinjinqiao Road, Pudong New Area, Shanghai, June 2012 Applicant after: Shanghai Haoruishi Intelligent Technology Co.,Ltd. Address before: Room 517, No. 1348 Xinjinqiao Road, Pudong New Area, Shanghai, June 2012 Applicant before: Shanghai Haoruishi Science and Technology Innovation Intelligent Equipment Co.,Ltd. |
|
CB02 | Change of applicant information | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |