CN116370186A - Schlemm's tube expansion bracket and manufacturing method - Google Patents
Schlemm's tube expansion bracket and manufacturing method Download PDFInfo
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- CN116370186A CN116370186A CN202310305807.5A CN202310305807A CN116370186A CN 116370186 A CN116370186 A CN 116370186A CN 202310305807 A CN202310305807 A CN 202310305807A CN 116370186 A CN116370186 A CN 116370186A
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- schlemm
- stent
- canal
- tube
- memory alloy
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- 229910001285 shape-memory alloy Inorganic materials 0.000 claims abstract description 20
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims abstract description 12
- 238000007493 shaping process Methods 0.000 claims abstract description 9
- 238000009954 braiding Methods 0.000 claims abstract description 8
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229910052759 nickel Inorganic materials 0.000 claims abstract description 6
- 229910052719 titanium Inorganic materials 0.000 claims abstract description 6
- 239000010936 titanium Substances 0.000 claims abstract description 6
- 210000001585 trabecular meshwork Anatomy 0.000 claims description 16
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 12
- 210000004087 cornea Anatomy 0.000 claims description 11
- 210000002159 anterior chamber Anatomy 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 229910000990 Ni alloy Inorganic materials 0.000 claims description 3
- 238000002513 implantation Methods 0.000 claims description 3
- 229910052715 tantalum Inorganic materials 0.000 claims description 3
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 claims description 3
- 238000009941 weaving Methods 0.000 claims description 3
- 238000004140 cleaning Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 239000000956 alloy Substances 0.000 abstract description 4
- 229910045601 alloy Inorganic materials 0.000 abstract description 3
- 238000010438 heat treatment Methods 0.000 abstract description 3
- 208000031481 Pathologic Constriction Diseases 0.000 abstract description 2
- 230000036262 stenosis Effects 0.000 abstract description 2
- 208000037804 stenosis Diseases 0.000 abstract description 2
- 210000001742 aqueous humor Anatomy 0.000 description 11
- 230000000694 effects Effects 0.000 description 6
- 230000004410 intraocular pressure Effects 0.000 description 6
- 238000005520 cutting process Methods 0.000 description 4
- 208000030533 eye disease Diseases 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 208000010412 Glaucoma Diseases 0.000 description 3
- 230000035515 penetration Effects 0.000 description 3
- 230000010339 dilation Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000005457 ice water Substances 0.000 description 2
- 238000009940 knitting Methods 0.000 description 2
- 230000003902 lesion Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000000750 progressive effect Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010016760 Flat anterior chamber of eye Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001746 atrial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000001886 ciliary effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000001328 optic nerve Anatomy 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- C—CHEMISTRY; METALLURGY
- C21—METALLURGY OF IRON
- C21D—MODIFYING THE PHYSICAL STRUCTURE OF FERROUS METALS; GENERAL DEVICES FOR HEAT TREATMENT OF FERROUS OR NON-FERROUS METALS OR ALLOYS; MAKING METAL MALLEABLE, e.g. BY DECARBURISATION OR TEMPERING
- C21D9/00—Heat treatment, e.g. annealing, hardening, quenching or tempering, adapted for particular articles; Furnaces therefor
- C21D9/0068—Heat treatment, e.g. annealing, hardening, quenching or tempering, adapted for particular articles; Furnaces therefor for particular articles not mentioned below
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
- C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
- C22F1/10—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of nickel or cobalt or alloys based thereon
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
- C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
- C22F1/16—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of other metals or alloys based thereon
- C22F1/18—High-melting or refractory metals or alloys based thereon
- C22F1/183—High-melting or refractory metals or alloys based thereon of titanium or alloys based thereon
Abstract
The invention provides a schlemm's tube (self-adaptive pump) expansion bracket and a manufacturing method thereof. The schlemm's tube expanding stent provided by the invention comprises: a cylindrical body configured to weave wires of a shape memory alloy into a lattice structure fabricated in a zigzag shape in a plurality of needles arranged in a circumferential direction (X) and a longitudinal direction (Y) of a cylindrical jig, respectively. The schlemm's tube expanding support is made of tubular mesh type design, is mostly composed of titanium, nickel and alloy thereof, is prepared after braiding, heat treatment and shaping, and has good supporting force, biocompatibility, shaping force and good braiding characteristics. The bracket is tightly combined with the narrow section of the schlemm pipe, and is not easy to shift. The schlemm's tube expanding support provided by the invention can generate continuous and soft radial expansion force which acts on the inner wall of the schlemm tube to recover the stenosis.
Description
Technical Field
The invention relates to the technical field of ophthalmic medical equipment, in particular to a schlemm's tube expansion bracket and a manufacturing method thereof.
Background
Glaucoma is a second generally blinding eye disease worldwide, the first largely irreversible blinding eye disease, which is a chronic, progressive eye disease that jeopardizes the optic nerve and vision function with a prevalence of 2-3%. In the treatment of glaucoma, lowering intraocular pressure and improving prognosis by changing the aqueous humor outflow and inflow balance are currently the most commonly used and accepted most effective means in the industry.
Aqueous humor is produced by the ciliary muscle epithelium, and its outflow is primarily through the trabecular meshwork distributed over the atrial corners into the schlemm's canal, and then is introduced into the aqueous humor vein back into the vein. In addition, about 5 to 25% of the aqueous humor is drained through the uveal-scleral pathway.
Traditional glaucoma surgery, such as trabeculotomy or trabeculectomy, is based on cutting the eye wall and creating a new aqueous flow path through the trabecular meshwork to the anterior chamber. The intraocular pressure is suddenly reduced due to the penetration of the anterior chamber during the operation, and complications such as shallow anterior chamber, low intraocular pressure and the like are easy to occur.
There is a new class of treatments that do not require penetration of the anterior chamber, i.e., mucotubular dilation procedures. In the small-sized tube dilatation operation, the dilatation condition and the effect of the Schlemm's tube play a key role in the success or failure of the operation. The small-size canal operation mainly injects a high-molecular viscoelastic agent into the Schlemm's canal to achieve the purposes of expanding the Schlemm's canal, reducing resistance of aqueous humor outflow, promoting aqueous humor drainage and reducing intraocular pressure.
However, the operation type cannot ensure the expansion effect of the Schlemm's canal and cannot maintain the expansion state of the Schlemm's canal for a long time, so that the provision of a device suitable for stably expanding the Schlemm's canal to reduce the outflow resistance of aqueous humor is a technical problem to be solved in the art.
Disclosure of Invention
The embodiment of the invention provides a schlemm's tube expansion bracket and a manufacturing method thereof, which are used for solving the problems in the prior art.
In order to achieve the above purpose, the present invention adopts the following technical scheme.
The schlemm's tube expanding support includes one cylindrical main body with memory alloy wire woven netted structure;
the schlemm's canal stent is adapted to be implanted within the schlemm's canal and is capable of continuously generating radial expansion forces such that the stenosed site of the schlemm's canal is restored to patency.
Preferably, the configuration of the cylindrical body includes a mesh stent, a tubular stent, a wound stent, and a ring stent.
Preferably, the cylindrical main body comprises a tantalum bracket, a titanium bracket, a nickel bracket and a titanium-nickel alloy bracket.
Preferably, the device further comprises a transmitter which is detachably connected with the monofilament net pipe and used for limiting the radial expansion of the monofilament net pipe;
when the schlemm's canal is expanded to a predetermined location within the schlemm's canal, the presenter is removed and the monofilament net-like canal is able to continue to create radial expansion forces such that the inner diameter of the schlemm's canal increases.
Preferably, the main body is woven by titanium-nickel memory alloy wires with the diameter range of 10-100 micrometers; the diameter of the body ranges from 50 to 500 microns.
Preferably, the implantation process comprises:
making an incision in a transparent corneal region of the limbus, supporting the transparent anterior corneal chamber using a viscoelastic agent; making a notch on the trabecular meshwork;
placing a Schlemm's canal stent within the Schlemm's canal using an intraocular forceps or a bolus, the Schlemm's canal being placed from an incision in the transparent cornea and trabecular meshwork into a preset position;
the viscoelastic agent of the anterior chamber of the transparent cornea is cleaned, and the incision of the transparent cornea region and the incision of the trabecular meshwork are watertight.
In a second aspect, the present invention provides a method of making a schlemm's tube expanded stent comprising:
s1, braiding memory alloy wires into a cylindrical net-shaped structure;
s2, shaping the net-shaped structure body in the environment of 400-600 ℃.
Preferably, the method further comprises placing the mesh structure into a presenter.
Preferably, in step S1, the mesh structure is a monofilament mesh structure, and the memory alloy wire is a titanium-nickel memory alloy wire.
The technical scheme provided by the embodiment of the invention can be seen that the schlemm's tube (self-adaptive pump) expansion bracket and the manufacturing method provided by the invention. The schlemm's tube expanding stent provided by the invention comprises: a cylindrical body configured to weave wires of a shape memory alloy into a lattice structure fabricated in a zigzag shape in a plurality of needles arranged in a circumferential direction (X) and a longitudinal direction (Y) of a cylindrical jig, respectively. The schlemm's tube expanding support is made of tubular mesh type design, is mostly composed of titanium, nickel and alloy thereof, is prepared after braiding, heat treatment and shaping, and has good supporting force, biocompatibility, shaping force and good braiding characteristics. The bracket is tightly combined with the narrow section of the schlemm pipe, and is not easy to shift. The schlemm's tube expanding support provided by the invention can generate continuous and soft radial expansion force which acts on the inner wall of the schlemm tube to recover the stenosis.
Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic illustration of a schlemm's tube stent according to the present invention;
FIG. 2 is a schematic view of the region of action of a schlemm's stent according to the present invention;
FIG. 3 is a schematic illustration of a schlemm's canal stent according to the present invention implanted therein;
FIG. 4 is a schematic view showing the working state of the schlemm's expanded stent after implantation according to the present invention;
fig. 5 is a schematic view of a schlemm's tube stent applied to the treatment of eye diseases.
In the figure:
1. main body 2 schlemm's canal 3. Stenosed area;
schlemm's canal dilating scaffold 503 limbal incision 504, lesion 505, iris 506, pupil 507, cornea 508, sclera.
Detailed Description
Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals refer to the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary only for explaining the present invention and are not to be construed as limiting the present invention.
As used herein, the singular forms "a", "an", "the" and "the" are intended to include the plural forms as well, unless expressly stated otherwise, as understood by those skilled in the art. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof. It will be understood that when an element is referred to as being "connected" or "coupled" to another element, it can be directly connected or coupled to the other element or intervening elements may also be present. Further, "connected" or "coupled" as used herein may include wirelessly connected or coupled. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
It will be understood by those skilled in the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
For the purpose of facilitating an understanding of the embodiments of the invention, reference will now be made to the drawings of several specific embodiments illustrated in the drawings and in no way should be taken to limit the embodiments of the invention.
The invention provides a schlemm's tube expansion bracket and a manufacturing method thereof, which are used for solving the following technical problems in the prior art:
there is a new class of treatments that do not require penetration of the anterior chamber, i.e., mucotubular dilation procedures. In the small-sized tube dilatation operation, the dilatation condition and the effect of the Schlemm's tube play a key role in the success or failure of the operation. The small-size canal operation mainly injects a high-molecular viscoelastic agent into the Schlemm's canal to achieve the purposes of expanding the Schlemm's canal, reducing resistance of aqueous humor outflow, promoting aqueous humor drainage and reducing intraocular pressure.
However, the operation type cannot ensure the expansion effect of the Schlemm's canal and cannot maintain the expansion state of the Schlemm's canal for a long time, so that the provision of a device suitable for stably expanding the Schlemm's canal to reduce the outflow resistance of aqueous humor is a technical problem to be solved in the art.
Referring to fig. 1, the invention provides a schlemm's tube expansion bracket, which comprises a cylindrical main body 1, wherein the cylindrical main body 1 is a net structure of a memory alloy wire knitting structure, and has good memory property and super elasticity.
As shown in fig. 2 to 4, the schlemm's expanded stent provided by the present invention is in a pre-compressed state when stored (when preparation is completed), and in use, the stent is left in the schlemm's tube 2 according to the difference between the deformation degree of the stent and the deformation degree of the stent by being implanted in the narrow region 3 of the lesion in the schlemm's tube 2, and the schlemm's tube 2 is continuously mechanically expanded to reduce the resistance of aqueous humor passing through the trabecular meshwork and thus reduce the intraocular pressure.
In the preferred embodiment provided by the invention, a mesh stent (wall stent), a tubular stent, a winding stent and a ring stent can be adopted according to the structural design requirement of the stent, and a memory alloy material such as a tantalum stent, a titanium stent, a nickel stent and a titanium-nickel alloy stent thereof is preferred according to the material design requirement. For example, the cylindrical body 1 has a monofilament net-like tubular structure of a titanium-nickel memory alloy wire braid structure. Specifically, the main body 1 of the monofilament net-shaped tubular structure is formed by weaving titanium-nickel memory alloy wires with the diameter range of 10-100 micrometers, and the diameter range of the monofilament net-shaped tube is 50-500 micrometers. In one more common type, the monofilament mesh tube has a length of 8mm and a diameter of 0.25mm.
In a preferred embodiment provided by the present invention, the stent further comprises a spreader detachably connected to the monofilament mesh tube for limiting radial expansion of the monofilament mesh tube prior to use so as to maintain it in a compressed state. When the device is used, the device and the monofilament net-shaped tube are placed in the narrow region of the schlemm's tube together, and then the device is withdrawn, at this time, the monofilament net-shaped tube can continuously generate radial expansion force, so that the inner diameter of the schlemm's tube is increased, and the narrow region is restored to be smooth.
In a preferred embodiment provided by the present invention, the procedure for implanting the present stent is as follows:
making incisions in the transparent corneal region and trabecular meshwork of the limbus, supporting the transparent anterior corneal chamber with a viscoelastic;
placing the Schlemm's canal stent within a Schlemm's canal using an intraocular forceps or a bolus, placing the Schlemm's canal from an incision in the transparent cornea and trabecular meshwork into a preset position;
cleaning the viscoelastic agent of the anterior chamber of the transparent cornea, watertight and transparent cornea and trabecular meshwork incisions, and completing the operation.
Wherein, the incision depth can be properly mastered according to the actual size of the expansion bracket, for example, a transparent cornea is used for making an incision of 2.2mm, and a trabecular meshwork is used for cutting the trabecular meshwork by using a trabecular meshwork cutting knife for cutting the trabecular meshwork by about 0.5-1 mm. Figure 5 shows the present stent in position and in operation as applied to the corneal region.
In a second aspect, the present invention provides a method for manufacturing the schlemm's tube expansion stent, comprising the following steps:
s1, weaving memory alloy wires into a net-shaped structure;
s2, shaping the net-shaped structure body at the temperature of 400-600 ℃. The shaped mesh structure is in a pre-compressed state.
Further, the cylindrical main body 1 is a monofilament net-shaped tubular structure of a titanium-nickel memory alloy wire knitting structure.
Further, the method includes placing the prepared monofilament net-like tube into a dispenser.
The invention also provides an embodiment for exemplarily showing the manufacturing and using effects of the expansion bracket provided by the invention.
The stent is a monofilament net-shaped metal stent woven by titanium-nickel wires, and is shaped for 5-60 minutes at a high temperature of 400-600 ℃. In the in vitro test process, the prepared monofilament net-shaped metal stent is in a softened state under the condition of 0-10 ℃ (ice water), the shape of the stent is changed in a certain range by rolling, a monofilament net-shaped tube in a precompressed state is constructed, the monofilament net-shaped tube is placed in a dispenser, and finally the dispenser and the monofilament net-shaped tube are placed in a narrow area of a schlemm's tube. When in use, the schlemm's tube is pushed out of the inner delivery device in the focus area above 33 ℃, the monofilament netlike tube can immediately generate continuous soft radial expansion force, and the monofilament netlike tube is restored to the original shape and acts on the inner wall of the tube, so that the narrow part is restored to be unobstructed.
In summary, the schlemm's tube expansion stent and the manufacturing method provided by the invention comprise the following steps: a cylindrical body configured to weave wires of a shape memory alloy into a lattice structure fabricated in a zigzag shape in a plurality of needles arranged in a circumferential direction (X) and a longitudinal direction (Y) of a cylindrical jig, respectively. The schlemm's tube expanding support is made of tubular mesh type design, is mostly composed of titanium, nickel and alloy thereof, is prepared after braiding, heat treatment and shaping, and has good supporting force, biocompatibility, shaping force and good braiding characteristics. The bracket is tightly combined with the narrow section of the schlemm pipe, and is not easy to shift. Meanwhile, the expansion bracket has the following characteristics: (1) The self-expanding schelmm tube and the anastomotic stoma inner stent of the titanium-nickel memory alloy have excellent biocompatibility, and have peculiar memory property and superelasticity. The inner bracket is in a softened state under the condition of 0-10 ℃ (ice water), the shape of the inner bracket is changed within a certain range, and the inner bracket is put into a transmitter; the inner support is pushed out at the temperature of above 33 ℃, can be immediately restored to the original shape, generates continuous soft radial expansion force and acts on the inner wall of the schelmm pipe to restore the patency of the narrow part. (2) The inner support has good super elasticity at body temperature, and can fluctuate along with the pulsation of a normal schelmm pipe, so that the schelmm pipe is kept smooth and has no uncomfortable feeling. (3) The two ends of the inner support are small circular arcs, so that the wall of the schelmm pipe can not be damaged. Simple operation and definite curative effect. (4) Can prevent stent blockage caused by bacterial infection, bleeding, inflammatory reaction, proliferation membrane, and pigmentation.
Those of ordinary skill in the art will appreciate that: the drawing is a schematic diagram of one embodiment and the modules or flows in the drawing are not necessarily required to practice the invention.
In this specification, each embodiment is described in a progressive manner, and identical and similar parts of each embodiment are all referred to each other, and each embodiment mainly describes differences from other embodiments. In particular, for apparatus or system embodiments, since they are substantially similar to method embodiments, the description is relatively simple, with reference to the description of method embodiments in part. The apparatus and system embodiments described above are merely illustrative, wherein the elements illustrated as separate elements may or may not be physically separate, and the elements shown as elements may or may not be physical elements, may be located in one place, or may be distributed over a plurality of network elements. Some or all of the modules may be selected according to actual needs to achieve the purpose of the solution of this embodiment. Those of ordinary skill in the art will understand and implement the present invention without undue burden.
The present invention is not limited to the above-mentioned embodiments, and any changes or substitutions that can be easily understood by those skilled in the art within the technical scope of the present invention are intended to be included in the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the protection scope of the claims.
Claims (9)
1. The schlemm's tube expanding support is characterized by comprising a cylindrical main body, wherein the cylindrical main body is a net structure of a memory alloy wire weaving structure;
the schlemm's canal expansion stent is used to be implanted into the schlemm's canal, and can continuously generate radial expansion force, so that the narrow part of the schlemm's canal is restored to be unobstructed.
2. The schlemm's tube expanding stent of claim 1, wherein the configuration of the cylindrical body comprises a mesh stent, a tubular stent, a wound stent, and a ring stent.
3. The schlemm's canal stent according to claim 1, wherein the material of the cylindrical body comprises tantalum stent, titanium stent, nickel stent and titanium-nickel alloy stent.
4. The schlemm's canal expansion stent according to claim 1, further comprising a presenter detachably connected to the monofilament mesh tube for limiting radial expansion of the monofilament mesh tube;
when the schlemm's canal is expanded to a predetermined position within the schlemm's canal, the presenter is removed and the monofilament net-like canal is able to continue to create radial expansion forces such that the inner diameter of the schlemm's canal increases.
5. The schlemm's tube expansion stent according to claim 1, wherein the main body is woven from titanium-nickel memory alloy wires having a diameter in the range of 10-100 microns; the diameter of the main body ranges from 50 to 500 micrometers.
6. The schlemm's canal expansion stent according to claim 1, wherein the implantation procedure comprises:
making an incision in a transparent corneal region of the limbus, supporting the transparent anterior corneal chamber using a viscoelastic agent; making a notch on the trabecular meshwork;
placing the Schlemm's canal stent within a Schlemm's canal using an intraocular forceps or a bolus, placing the Schlemm's canal from an incision in the transparent cornea and trabecular meshwork into a preset position;
cleaning the viscoelastic agent of the anterior chamber of the transparent cornea, watertight the incision of the transparent cornea region and the incision of the trabecular meshwork.
7. A method of making a schlemm's stent comprising:
s1, braiding memory alloy wires into a cylindrical net-shaped structure;
s2, shaping the net-shaped structure body in the environment of 400-600 ℃.
8. The method of manufacturing of claim 7, further comprising placing the mesh structure into the dispenser.
9. The method according to claim 8, wherein in step S1, the mesh structure is a monofilament mesh structure, and the memory alloy wire is a titanium-nickel memory alloy wire.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310305807.5A CN116370186A (en) | 2023-03-27 | 2023-03-27 | Schlemm's tube expansion bracket and manufacturing method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310305807.5A CN116370186A (en) | 2023-03-27 | 2023-03-27 | Schlemm's tube expansion bracket and manufacturing method |
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| CN116370186A true CN116370186A (en) | 2023-07-04 |
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| CN202310305807.5A Pending CN116370186A (en) | 2023-03-27 | 2023-03-27 | Schlemm's tube expansion bracket and manufacturing method |
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