CN116370008B

CN116370008B - Multi-pitch woven support

Info

Publication number: CN116370008B
Application number: CN202310452021.6A
Authority: CN
Inventors: 张宁; 付诗; 张淼; 刘辰洋
Original assignee: Shanghai Li Kai Technology Co ltd
Current assignee: Shanghai Li Kai Technology Co ltd
Priority date: 2023-04-24
Filing date: 2023-04-24
Publication date: 2024-01-30
Anticipated expiration: 2043-04-24
Also published as: CN116370008A

Abstract

The application relates to a multisection woven scaffold, comprising: the tubular knitting machine comprises a knitting main body, wherein the knitting main body is a tubular knitting fabric comprising more than two groups of different knitting pitches, first knitting wires are respectively knitted clockwise and anticlockwise on a knitting core rod to form a first knitting pipe, the straight line distance of the first knitting wires around the knitting core rod is a first pitch, other knitting wires are spirally knitted on the knitting core rod, and the first pitch is smaller than the knitting pitch of the other knitting wires. By arranging two or more tubular braided fabrics with different braiding pitches on the braided main body, the braided main body in a bent state of the braided main body in a blood vessel bent section is in a bending state due to the design of the big and small sections, and the curvature of braiding wires with small pitches is consistent, and the trend is consistent in the bending state; the large-pitch braided wire has stronger capability of adhering to and conforming to a blood vessel at the blood vessel bending section, can reduce the deformation degree of the lumen of the small-pitch braided wire in the state of bending the blood vessel to a certain extent, and improves the integral deformation resistance of the braided body.

Description

Multi-pitch woven support

Technical Field

The application relates to the technical field of medical instruments, in particular to a multi-pitch braided stent.

Background

Minimally invasive interventional surgery is a common treatment means for treating intracranial aneurysms, and the main treatment technology for the intracranial aneurysms currently comprises different methods such as spring coil stuffing, stent graft implantation, stent-assisted spring coil stuffing, blood flow guiding devices and the like. However, for some more complex intracranial aneurysms, such as large and huge saccular aneurysms, wide carotid aneurysms, fusiform aneurysms, and interlayer aneurysms, the treatment process is more complex, the complications rate is high during operation and after operation, and the recurrence rate is high after operation, so that the intracranial aneurysms are treated by using a more traditional spring ring or a stent-assisted spring ring filling technology, and the phenomena of long time consumption during operation, difficult complete occlusion of the neck of the aneurysm and incomplete occlusion of the aneurysm exist; while most of the film covered stent is difficult to be used for bending blood vessels, in-place is difficult, and siphon bending and above parts are not applicable; blood flow guiding devices, which are currently popular in the market, are increasingly favored by doctors due to their better compliance, neck covering effect and blood flow guiding capability.

However, the adherence effect, mechanical properties and positioning of the blood flow guiding device are always important clinical concerns. In particular, in the vascular curved section, the support capability of the braided stent after radial opening and opening is still required to be improved.

Disclosure of Invention

In view of this, the present application proposes a multi-pitch braided stent comprising a braided body including two or more sets of tubular braids having different braiding pitches; the first braiding wires are braided on the braiding core rod clockwise and anticlockwise respectively to form a first braiding pipe, and the linear distance of the first braiding wires around the braiding core rod is a first pitch; the other braided wires are spirally braided on the braided core rod, and the first pitch is smaller than the braiding pitch of the other braided wires.

In one possible implementation, the braiding pitch of the remaining braiding filaments except the first braiding filament is an integer multiple of the first pitch.

In one possible embodiment, the remaining braiding wires, except for the first braiding wire, are braided clockwise and/or counterclockwise on the braiding mandrel.

In one possible implementation, the length of the first braided tube is equal to the axial length of the remaining braided filaments in the braided body.

In one possible implementation, at least a maximum braiding pitch the braiding filaments have a filament diameter greater than a filament diameter of the first braiding filaments.

In one possible implementation, the braided filaments braided clockwise and braided counterclockwise are at an included angle of 20 ° -160 ° in the same pitch.

In one possible implementation, the woven body is integrally formed.

In one possible implementation, the end of the woven body has a developing tip.

In one possible implementation, both ends of the woven body are in a flared structure.

In one possible implementation, the braided filaments have a filament diameter between 20 microns and 100 microns, and a portion of the braided filaments have a filament diameter greater than a filament diameter of another portion of the braided filaments.

In one possible implementation, the material of the braided wire is a memory metal, and the braided wire is made of a single material or a mixture of two or more materials.

In one possible implementation, the braided body is made using nickel titanium braided wire and platinum braided wire mixed braiding or cobalt chromium braided wire and platinum braided wire mixed braiding.

In one possible implementation manner, the first braiding wire and the other braiding wires adjacent to the first braiding wire are mutually wound and fixed at the end part of the braiding body, and both ends of the braiding body are of a closed structure.

In one possible implementation manner, the knitting main body is sequentially divided into a proximal conveying section, a middle flow blocking section and a distal opening section in a proximal-to-distal direction; in the middle choke section, the first braided tube has an intersection with the remaining braided filaments, the remaining braided filaments having an intersection with at least the first braided tube, such that more than two sets of the tubular braids are interwoven into the same unitary body in the middle choke section; the first braided wire is twisted with the rest braided wires at the proximal end side of the middle flow blocking section, and the twisting part is the proximal end conveying section; the first braided wire is twisted with the rest of the braided wires at the distal end side of the middle flow blocking section, and the twisted part is the distal opening section.

In one possible implementation manner, in the proximal conveying section and the distal opening section, the braiding wires of the first braided tube and the other braiding wires adjacent to the braiding wires are twisted and fixed in the same direction or opposite directions at two end positions of the braided body to form a closed twisting structure; or in the proximal conveying section, part of the braiding wires of the first braided tube and part of the other braiding wires are twisted and fixed at the two ends of the braided body in the same direction or opposite directions to form a semi-closed twisting structure.

In one possible implementation manner, at least the distal end of the braiding main body is a closed and wound structure, and the braiding wires adjacent to the braiding wires are bent in an arc shape at the end of the braiding main body to form the closed and wound structure.

In one possible implementation manner, the knitting main body is sequentially divided into a proximal conveying section, a middle flow blocking section and a distal opening section in a proximal-to-distal direction; in the middle choke section, the first braided tube has an intersection with the remaining braided filaments, the remaining braided filaments having an intersection with at least the first braided tube, such that more than two sets of the tubular braids are interwoven into the same unitary body in the middle choke section; the proximal conveying section is in a loose structure, and the braiding wires in the proximal conveying section are braided to the proximal tail part along the original track; the distal opening section is in a loose structure, and the braiding wires in the section are braided distally to a distal tail along an original track.

In one possible implementation, two adjacent closed structures are arranged in a staggered manner along the circumferential direction of the woven body, or two adjacent loose structures are arranged in a staggered manner along the circumferential direction of the woven body.

The beneficial effects of this application: by arranging more than two tubular braided fabrics with different braiding pitches on the braided main body, the braided main body in a bent state of the vascular bending section is in a bending state due to the design of the big and small sections of the tubular braided fabrics, and the curvature of the braided wires with small pitches is consistent (especially the curvature of the first braided wires with the minimum pitches) and the trend is consistent in the bending state; the large-pitch braided wire has stronger capability of adhering to and conforming to a blood vessel at the blood vessel bending section, can reduce the deformation degree of the lumen of the small-pitch braided wire in the state of bending the blood vessel to a certain extent, and improves the integral deformation resistance of the braided body.

Other features and aspects of the present application will become apparent from the following detailed description of exemplary embodiments, which proceeds with reference to the accompanying drawings.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate exemplary embodiments, features and aspects of the present application and together with the description, serve to explain the principles of the present application.

FIG. 1 illustrates a schematic side structural view of a multi-segmented braided stent in accordance with an embodiment of the present application;

FIG. 2 illustrates a schematic side structural view of a multi-segmented braided stent in accordance with another embodiment of the present application;

FIG. 3 illustrates an axial view of an end of a multi-segmented braided stent in a closed twist configuration in accordance with an embodiment of the present application;

FIG. 4 illustrates an axial view of an end of a multi-segmented braided stent in a closed loop configuration in accordance with an embodiment of the present application;

FIG. 5 illustrates a partial enlarged view of a closed twist structure with the ends of a multi-segmented braided stent in a staggered arrangement in accordance with an embodiment of the present application;

FIG. 6 illustrates a partial enlarged view of a semi-closed twist structure with the ends of a multi-segmented braided stent staggered in accordance with an embodiment of the present application;

fig. 7 shows a partial enlarged view of a closed loop structure with the ends of the multi-segmented braided stent offset in position according to an embodiment of the present application.

Detailed Description

Various exemplary embodiments, features and aspects of the present application will be described in detail below with reference to the accompanying drawings. In the drawings, like reference numbers indicate identical or functionally similar elements. Although various aspects of the embodiments are illustrated in the accompanying drawings, the drawings are not necessarily drawn to scale unless specifically indicated.

It should be understood, however, that the terms "center," "longitudinal," "transverse," "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counter-clockwise," "axial," "radial," "circumferential," and the like indicate or are based on the orientation or positional relationship shown in the drawings, and are merely for convenience of description or to simplify the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be configured and operated in a particular orientation, and therefore should not be construed as limiting the present application.

Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present application, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.

The word "exemplary" is used herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.

In addition, numerous specific details are set forth in the following detailed description in order to provide a better understanding of the present application. It will be understood by those skilled in the art that the present application may be practiced without some of these specific details. In some instances, methods, means, elements, and circuits have not been described in detail as not to unnecessarily obscure the present application.

FIG. 1 illustrates a schematic side structural view of a multi-segmented braided stent in accordance with an embodiment of the present application; FIG. 2 illustrates a schematic side structural view of a multi-segmented braided stent in accordance with another embodiment of the present application; FIG. 3 illustrates an axial view of an end of a multi-segmented braided stent in a closed twist configuration in accordance with an embodiment of the present application;

FIG. 4 illustrates an axial view of an end of a multi-segmented braided stent in a closed loop configuration in accordance with an embodiment of the present application; FIG. 5 illustrates a partial enlarged view of a closed twist structure with the ends of a multi-segmented braided stent in a staggered arrangement in accordance with an embodiment of the present application; FIG. 6 illustrates a partial enlarged view of a semi-closed twist structure with the ends of a multi-segmented braided stent staggered in accordance with an embodiment of the present application; fig. 7 shows a partial enlarged view of a closed loop structure with the ends of the multi-segmented braided stent offset in position according to an embodiment of the present application.

As shown in fig. 1-7, the multi-pitch braided stent comprises: the main body 10 is knitted, the main body 10 comprises more than two groups of tubular knitted fabrics with different knitting pitches, wherein the first knitted wires 101 are respectively knitted clockwise and anticlockwise on a knitting mandrel to form a first knitted tube, the straight line distance of the first knitted wires 101 around the knitting mandrel is a first pitch P1, the rest of the knitted wires are spirally knitted on the knitting mandrel, and the first pitch P1 is smaller than the knitting pitch of the rest of the knitted wires.

In this embodiment, by providing the woven body 10 with two or more tubular braids having different braiding pitches, the woven body 10 is in a bent state in the blood vessel bent section due to the design of the size section thereof, and the curvature of the braiding wires of the small pitch is uniform (particularly, the first braiding wires 101 of the minimum pitch) and the trend is uniform in the bent state; the large-pitch braided wire has stronger capability of adhering to and conforming to the blood vessel at the blood vessel bending section, can reduce the deformation degree of the lumen of the small-pitch braided wire in the state of bending the blood vessel to a certain extent, and improves the integral deformation resistance of the braided body 10.

It should be pointed out especially that the multisection is apart from weaving the support of this application is particularly useful for when the fine pitch braided wire is denser, and the acute angle of camber is less in the blood vessel is curved, piles up between the fine pitch braided wire, through increasing the tubular braid that the larger large pitch braided wire of relative pitch constitutes, the effectual lumen of reduction is to the intraductal risk of collapsing and little curved side wall non-sticking of support, avoids causing the narrow condition of support.

In one embodiment, the braiding pitches of the remaining braiding wires except for the first braiding wire 101 are integer multiples of the first pitch P1.

In this embodiment, the first pitch P1 of the first braided wire 101 is the smallest, and is mainly used to form a high-pore-density flow guiding layer, which serves as a blood flow guide, while the pitches of the remaining braided wires are positive integer multiples.

The large pitch referred to herein is a larger weaving pitch relative to the first pitch P1, while the small pitch means a weaving pitch smaller relative to the pitch, the smallest being only the first pitch P1.

Therefore, it is preferable that the pore density of the first braided tube is 60 or more per mm ² 。

As shown in fig. 2, in one embodiment, the woven body 10 includes three kinds of woven wires with different pitches, which are sequentially arranged from small to large according to the pitches: first braided wire 101, second braided wire 102, and third braided wire 103.

In this embodiment, the multiple pitch design provides unique mechanical properties that provide higher radially outward expansion and radial support forces than conventional stents.

In one embodiment, the remaining braided filaments, except for first braided filaments 101, are braided clockwise and/or counterclockwise on the braiding mandrel.

More specifically, in one embodiment, there are two different pitches of the braided wires, wherein the first braided wire 101 is arranged to be braided in a clockwise and counterclockwise spiral, and the braiding pitches are both a first pitch P1, denoted as P1; the second braided wire 102 has one or more braiding pitches Pm, pm=np1, where n is a positive integer greater than 1, and may exist alone with a single helical direction or both helical directions.

In one embodiment, the length of the first braided tube is equal to the axial length of the remaining braided filaments in the braided body 10.

In this embodiment, the first braiding wires 101 having the first pitch are braided together in the clockwise and counterclockwise directions to form a single braid, which is referred to herein as a first braided tube, and the second braiding wires 102 are also "fed" into and "out" of the first braided tube at different positions when the second braiding wires 102 are rotated about the braiding mandrel, and the points at which the braided wires feed into and out of the first braided tube and intersect with the first braiding wires 101 are referred to herein as intersection points. That is, the remaining braided tubes larger than the first pitch are braided on the basis of the first braided tube, and the braided body 10 in this application is preferably integrally braided.

In one particular embodiment, at least the maximum braiding pitch braiding filaments have a filament diameter greater than the filament diameter of first braiding filaments 101.

In this embodiment, at least the wire material of the largest pitch braided wire is replaced with a larger wire diameter so that the multi-pitch braided stent can further reduce the likelihood of deformation.

In one embodiment, the filaments woven clockwise and counterclockwise at the same pitch form an included angle of 20 ° -160 °.

In one embodiment, the woven body 10 is integrally formed.

In one embodiment, the end of the woven body 10 has a developing tip.

In one embodiment, the two ends of the woven body 10 are in a flared configuration.

In one embodiment, the filaments of the braid have a filament diameter between 20 microns and 100 microns, and a portion of the braid has a filament diameter greater than a filament diameter of another portion of the braid.

In the embodiment, the mixed braided wires and part of the braided wires have larger wire diameters, so that the area of the multi-section braided stent attached to the microcatheter during delivery can be effectively reduced, the friction resistance is reasonably reduced, and the operation of delivering to the distal end by an operator is easy.

In one embodiment, the material of the knitting yarn is a memory metal, and the knitting yarn is made of a single material or a mixture of two or more materials.

In one embodiment, the woven body 10 is made using nickel titanium woven wire and platinum woven wire mixed or cobalt chromium woven wire and platinum woven wire mixed.

In one embodiment, the first braided wire 101 and the other neighboring braided wires are intertwined and fixed at the end of the braided body 10, and both ends of the braided body 10 are closed structures.

In one embodiment, the knitted body 10 is divided into a proximal delivery segment 121, a middle flow-blocking segment 122, and a distal opening segment 123 in sequence in a proximal to distal direction thereof, wherein in the middle flow-blocking segment 122, a first knitted tube has an intersection with the remaining knitted wires, and wherein at least the remaining knitted wires have an intersection with the first knitted tube, such that two or more sets of tubular knitted articles are interwoven as a single body in the middle flow-blocking segment 122, the first knitted wire 101 is twisted with the remaining knitted wires on a proximal side of the middle flow-blocking segment 122, the twisted portion is the proximal delivery segment 121, the first knitted wire 101 is twisted with the remaining knitted wires on a distal side of the middle flow-blocking segment 122, and the twisted portion is the distal opening segment 123.

In this embodiment, during one revolution of the second braided wire 102 along the braiding mandrel, the second braided wire 102 enters the first braided tube once and exits the braided tube Zhou Yici, and the intersection points of the first braided wire 101 and the second braided wire 102 are all referred to herein as intersection points, and the following is the same; it is also possible that the second braided wire 102 is fed into the first braided tube twice and then discharged from the inside of the first braided tube to the outer periphery once during three turns of the second braided wire 102 along the braiding mandrel, and the first braided wire 101 and the second braided wire 102 intersect at an intersection point.

In one embodiment, in the proximal conveying section 121 and the distal opening section 123, the braiding wires of the first braided tube and the remaining braiding wires adjacent thereto are twisted and fixed in the same direction or opposite directions at both end positions of the braided body to form a closed twisting structure 131; alternatively, in the proximal delivery segment 121, a portion of the braided filaments of the first braided tube are twisted and secured with a portion of the remaining braided filaments in the same direction or in opposite directions at the two end positions of the braided body to form a semi-closed twist structure 132.

It should be noted that, as shown in fig. 5, the distal end of the braided body 10 must be a closed twist structure 131, or be processed in other ways, so that the entire distal end is curved to avoid damage to the human body, and the proximal delivery segment 121 is not required to take excessive protective measures due to its direct contact with the delivery device. Only part of the inner and outer braided wires can be twisted and fixed in the same direction or opposite directions to form a semi-closed twisting structure 132, as shown in fig. 6; may also be formed in a closed twist structure 131 consistent with the structure of the distal opening section 123.

More specifically, the closed twist structure 131 is: at the beginning or ending of braiding, the total filament head z involved in braiding is first divided into several parts, and the braided filaments in each part are further divided into two bundles which are rotated in the same direction or opposite directions respectively to form stable filament bundles, and then the two filament bundles are bound together in parallel to form the complete closed twist structure 131.

In another embodiment, the semi-closed twist structure 132 consists of: when knitting is started or finished, cutting the equal number of knitting yarns which are uniformly distributed in the circumferential direction and rotate in the same direction or opposite directions in part of the total spinning head z participating in knitting, further dividing the rest of knitting yarns into a plurality of parts, dividing the knitting yarns in each part into two bundles which rotate clockwise and anticlockwise respectively to form stable yarn bundles, and then binding the two yarn bundles together in parallel to form a final semi-closed twisting end.

More specifically, one method of closed end wrap around weave design is: the braiding mandrel is perforated and assembled with stainless steel nails, the braiding wires on the carrier are passed around the stainless steel nails to form a closed loop 133, and the braiding wires passed around the stainless steel nails are then connected to another carrier. On this basis, the carrier is woven in accordance with a predetermined trajectory to form a support with a closed loop structure 133 at the end. After braiding to the other end, the braiding mandrel is removed and the braiding wire is manually operated to bypass the stainless steel pin to form another closed loop structure 133.

In one embodiment, when the braiding main body 10 has the closed twisting structure 131 or the closed wrapping structure 133, two adjacent closed twisting structures 131 are arranged in a staggered manner along the circumferential direction of the braiding main body 10; or two adjacent closed loop structures 133 are arranged offset along the circumferential direction of the knitted body 10.

In this embodiment, as shown in fig. 5 to 7, at the end of the woven main body 10, adjacent closed structures are arranged in a staggered manner along the circumferential direction of the stent, and when the double-layer woven stent of the present application is compressed, the end staggering enables a plurality of adjacent closed structures to be better abducted, so that the stent is easier to compress.

In one embodiment, at least the distal end of the woven body 10 is a closed loop structure 133, and the adjacent woven filaments are bent in an arc shape at the end of the woven body 10 to form the closed loop structure 133.

In one embodiment, the knitted body 10 is divided into a proximal delivery section 121, a middle flow blocking section 122 and a distal opening section 123 in sequence in a proximal to distal direction thereof, wherein in the middle flow blocking section 122, a first knitted tube has an intersection with the rest of the knitted wires, and the rest of the knitted wires have an intersection with at least the first knitted tube, so that two or more sets of tubular knitted fabrics are interwoven into the same whole in the middle flow blocking section 122, the proximal delivery section 121 has a loose structure, the knitted wires in the section are knitted proximally to a proximal tail along an original track, and the distal opening section 123 has a loose structure, and the knitted wires in the section are knitted distally to a distal tail along the original track.

In one embodiment, two adjacent closed structures are offset along the circumference of the knitted body 10, or two adjacent loose structures are offset along the circumference of the knitted body 10.

In one embodiment, a multi-pitch woven stent is prepared by the following steps: the integral braiding and forming of the multi-section distance braiding bracket is realized through braiding, and the integral braiding and forming specifically comprises the following steps: by controlling the braiding speed of the braiding wires and adjusting the braiding pitch of the braiding wires, the braiding wires with different pitches are uniformly distributed in the braiding main body 10, and then the braided and formed bracket is subjected to heat treatment shaping and is taken down, the two ends can be subjected to laser welding so as to improve the structural stability of the bracket. And the end portion of the woven body 10 is provided with a hollow tube which is not permeable to the radio waves to improve the end portion developing ability.

The embodiments of the present application have been described above, the foregoing description is exemplary, not exhaustive, and not limited to the embodiments disclosed. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the various embodiments described. The terminology used herein was chosen in order to best explain the principles of the embodiments, the practical application, or the improvement of technology in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.

Claims

1. The multi-pitch braided stent is characterized by comprising a braided main body, wherein the braided main body comprises more than two groups of tubular braided fabrics with different braiding pitches;

the first braiding wires are braided on the braiding core rod clockwise and anticlockwise respectively to form a first braiding pipe, and the linear distance of the first braiding wires around the braiding core rod is a first pitch;

the other braided wires are spirally braided on the braiding mandrel, and the first pitch is smaller than the braiding pitch of the other braided wires;

the first braiding wires and other braiding wires adjacent to the first braiding wires are mutually wound and fixed at the end part of the braiding body, and both ends of the braiding body are of a closed structure;

the braiding main body is sequentially divided into a proximal conveying section, a middle flow blocking section and a distal opening section in the direction from the proximal end to the distal end;

in the middle choke section, the first braided tube has an intersection with the remaining braided filaments, and the remaining braided filaments have an intersection with at least the first braided tube, so that two or more sets of the tubular braids are interwoven into the same whole in the middle choke section.

2. The multi-pitch woven stent of claim 1, wherein the weaving pitches of the remaining weaving filaments except for the first weaving filament are positive integer multiples of the first pitch.

3. The multi-pitch braided stent of claim 1, wherein the remaining braided filaments, except for the first braided filaments, are braided clockwise and/or counterclockwise on the braided mandrel.

4. A multi-segmented braided stent according to claim 3 wherein the length of the first braided tube is equal to the axial length of the remaining braided filaments in the braided body.

5. The multi-pitch woven stent of claim 1 wherein at least a maximum weaving pitch woven wire has a wire diameter greater than a wire diameter of the first woven wire.

6. The multi-segmented braided stent of any one of claims 1-5, wherein the braided filaments braided clockwise and braided counterclockwise at the same pitch form an included angle of 20 ° to 160 °.

7. The multi-segmented braided stent of any one of claims 1-5, wherein the braided body is integrally formed.

8. The multi-segmented braided stent of any one of claims 1-5, wherein the braided filaments have a filament diameter between 20 microns and 100 microns;

the end part of the braiding main body is provided with a developing end;

and two ends of the woven main body are in flaring structures.

9. The multi-segmented braided stent of any one of claims 1-5, wherein the braided filaments are made of memory metal and the braided filaments are made of a single material or a mixture of two or more materials.

10. The multi-pitch braided stent of claim 9, wherein the braided body is made using nickel-titanium braided wire and platinum braided wire mixed braiding or cobalt-chromium braided wire and platinum braided wire mixed braiding.

11. The multi-segmented braided stent of claim 10, wherein,

the first braided wire is twisted with the rest braided wires at the proximal end side of the middle flow blocking section, and the twisting part is the proximal end conveying section;

the first braided wire is twisted with the rest of the braided wires at the distal end side of the middle flow blocking section, and the twisted part is the distal opening section.

12. The multi-segmented braided stent of claim 11, wherein in the proximal delivery segment and the distal opening segment, the braided filaments of the first braided tube are twisted with the remaining braided filaments adjacent thereto in the same direction or in opposite directions at both end positions of the braided body to form a closed twisted structure;

or in the proximal conveying section, part of the braiding wires of the first braided tube and part of the other braiding wires are twisted and fixed at the two ends of the braided body in the same direction or opposite directions to form a semi-closed twisting structure.

13. The multi-segmented braided stent of claim 11, wherein at least the distal end of the braided body is a closed loop structure, and the braided filaments adjacent to the first braided filaments are bent in an arc shape at the end of the braided body to form the closed loop structure.

14. The multi-segmented braided stent of claim 1, wherein the proximal delivery segment is in a loose configuration, the braided filaments in the segment being braided proximally along an original trajectory to a proximal tail;

the distal opening section is in a loose structure, and the braiding wires in the section are braided distally to a distal tail along an original track.

15. The multi-segmented braided stent of any one of claims 11-14, wherein adjacent two of the closure structures are offset along the circumference of the braided body.

16. The multi-pitch woven stent of claim 14 wherein adjacent two of the loose structures are offset along the circumference of the woven body.