CN116350935A - Electrical stimulation and electroencephalogram recording integrated device - Google Patents
Electrical stimulation and electroencephalogram recording integrated device Download PDFInfo
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- CN116350935A CN116350935A CN202111619228.5A CN202111619228A CN116350935A CN 116350935 A CN116350935 A CN 116350935A CN 202111619228 A CN202111619228 A CN 202111619228A CN 116350935 A CN116350935 A CN 116350935A
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- 238000000537 electroencephalography Methods 0.000 claims description 24
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0484—Garment electrodes worn by the patient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/251—Means for maintaining electrode contact with the body
- A61B5/256—Wearable electrodes, e.g. having straps or bands
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/263—Bioelectric electrodes therefor characterised by the electrode materials
- A61B5/266—Bioelectric electrodes therefor characterised by the electrode materials containing electrolytes, conductive gels or pastes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/263—Bioelectric electrodes therefor characterised by the electrode materials
- A61B5/27—Conductive fabrics or textiles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
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Abstract
The invention discloses an electric stimulation and electroencephalogram recording integrated device, which comprises an electroencephalogram recording electrode, an electrode upper seat, an electrode lower seat, a supporting body, an electric stimulation electrode, a conductive medium and an upper plug-in; the electroencephalogram recording electrode is embedded in the electrode upper seat or the electrode lower seat, and the electric stimulation electrode is integrally packaged in the upper plug-in; the electrode upper seat and the electrode lower seat form an electrode seat, and the electrode seat is arranged on a support body according to an electroencephalogram international universal positioning system; the upper plug-in is fixed on the upper electrode seat, and a conductive medium is arranged in the cavity of the upper plug-in. The integrated device for the electrical stimulation and the electroencephalogram recording can rapidly realize the positioning of the electrical stimulation electrode, the electrical stimulation electrode is convenient to replace, and the real-time synchronization and the organic fusion of the electrical stimulation and the electroencephalogram recording are realized.
Description
Technical Field
The invention relates to an integrated device for electrical stimulation and electroencephalogram recording, which is used for electrical stimulation and electroencephalogram recording and is particularly suitable for application scenes of multiple modes of electroencephalogram and electrical stimulation.
Background
With the continued development of neuromodulation techniques, high-focus transcranial direct current stimulation (HD-tDCS) has become a research hotspot for cognitive neuroscience, psychiatry, and neurorehabilitation medicine. The HD-tDCS technology is widely used for treating chronic pain, epilepsy, depression, parkinsonism and other diseases clinically. In the electrical stimulation study, researchers are very concerned about the effects after electrical stimulation, and electroencephalogram is an effective way to evaluate the effects after electrical stimulation. The combination of the HD-tDCS and the EEG not only can effectively evaluate the electric stimulation effect and optimize the electric stimulation parameters, but also can pre-classify patients and provide a personalized accurate stimulation scheme. The HD-tDCS and EEG multi-mode technology combined has become a brain science research trend, and has great application potential in the research of treating various neuropsychiatric diseases and neuro-electrophysiological mechanisms. The electrode is used as key hardware for collecting HD-tDCS and EEG signals, and directly influences the overall efficacy of the HD-tDCS/EEG combined technology. At present, an integrated device for HD-tDCS and EEG recording is lacked, so that the HD-tDCS and the EEG recording are convenient and synchronous to carry out, and a closed loop feedback system for regulation, monitoring and regulation is formed. The current HD-tDCS/EEG combination can only be realized by inserting a recording electrode on an individual stimulation site, and the stimulation same-point position is not conveniently realized on an international general point position system such as 10-20 of EEG. This not only brings operational inconvenience to practical applications, but also makes it difficult to achieve efficient fusion of HD-tDCS with EEG recordings. Therefore, development of an integrated device for electrical stimulation and electroencephalogram acquisition is needed. In addition, the positioning of the electro-stimulation electrode is troublesome, and a fast-installed and self-positioned electro-stimulation electrode needs to be developed.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a rapid positioning and electrical stimulation and electroencephalogram acquisition integrated device.
The technical scheme of the invention is as follows:
an electrical stimulation and electroencephalogram recording integrated device comprises an electroencephalogram recording electrode, an electrode upper seat, an electrode lower seat, a supporting body, an electrical stimulation electrode, a conductive medium and an upper plug-in; the electroencephalogram recording electrode is embedded in the electrode upper seat or the electrode lower seat, and the electric stimulation electrode is integrally packaged in the upper plug-in; the electrode upper seat and the electrode lower seat form an electrode seat, and the electrode seat is arranged on the support body according to an international electroencephalogram positioning system; the upper plug-in is fixed on the upper electrode seat, and a conductive medium is arranged in the cavity of the upper plug-in.
The further technical scheme is as follows:
the electric stimulation and electroencephalogram recording integrated device is characterized in that a notch is arranged on one side of the upper plug-in unit, which is opposite to the electroencephalogram recording electrode, so that the conductive medium is contacted with the electroencephalogram recording electrode.
The upper plug-in is fixed on the electrode upper seat through an extrusion groove or a clamping groove.
The electrical stimulation and electroencephalogram recording integrated device is characterized in that a conductive medium injection hole is formed in the top end of an upper plug-in; the conductive medium is fluid conductive medium and is injected through the conductive medium injection hole.
The electric stimulation and electroencephalogram recording integrated device is characterized in that the conductive medium is a water-absorbing material immersed with electrolyte solution, and the water-absorbing material is selected from one of sponge, cotton fiber and conductive gel.
The electric stimulation and electroencephalogram recording integrated device is characterized in that an electric stimulation electrode is made of silver/silver chloride plating layers, silver/silver chloride powder or inert conductor materials.
The electrode upper seat and the electrode lower seat of the electric stimulation and electroencephalogram recording integrated device are detachably connected and fixed on the support body through screw knobs, clamping grooves or extrusion; or is undetachable and is fixed on the support body in a riveting or bonding way; or is an integrally formed whole.
The electrical stimulation and electroencephalogram recording integrated device is characterized in that an electrical stimulation electrode is fixed on the top or the inner wall of an upper plug-in.
The support body of the electric stimulation and electroencephalogram recording integrated device is one of a cap, a helmet and a headband.
The electric stimulation and electroencephalogram recording integrated device is characterized in that the conductive medium contacted with the electroencephalogram recording electrode and the electric stimulation electrode is a fluid conductive medium or a water-absorbing material immersed with electrolyte solution.
The electroencephalogram recording electrode and the electric stimulation electrode of the integrated device are respectively contacted with the water absorbing material immersed with the electrolyte solution and the fluid-shaped conductive medium.
The electrode lower seat of the electric stimulation and electroencephalogram recording integrated device is in a horn shape.
The bottom end of the electrode upper seat of the electric stimulation and electroencephalogram recording integrated device is provided with a horn-shaped expansion end.
The electrode lower seat or the expansion end of the electric stimulation and electroencephalogram recording integrated device is internally provided with a plurality of comb-shaped teeth.
The electrical stimulation and electroencephalogram recording integrated device provided by the invention has the advantages that:
the invention provides an electrical stimulation and electroencephalogram recording integrated device, which integrates an electroencephalogram recording electrode and an electrical stimulation electrode. The electrical stimulation electrode is conveniently placed on the electrode upper seat of the electroencephalogram recording electrode on international universal points such as 10-20, 10-10, 10-5 and the like, so that the real-time synchronization of the electrical stimulation and the electroencephalogram recording is realized. The rapid and accurate positioning of the electric stimulation electrode is realized by skillfully utilizing the international universal electroencephalogram positioning systems of 10-20 and the like. The electric stimulation electrode or the upper plug-in unit integrally packaged with the electric stimulation electrode can be used as an independent component, so that later maintenance and replacement are facilitated. The electric stimulation electrode easy to move and install is greatly convenient for selecting different stimulation schemes. The horn-shaped electrode lower seat or the expansion end can effectively increase the effective contact area of the electrode and the scalp, effectively reduce the electrode-skin impedance, reduce the current density penetrating the scalp below the stimulation electrode, provide comfortable feeling of a high subject, and avoid pain stimulation, thereby improving the electric stimulation effect and the electroencephalogram recording signal quality. The comb-shaped electrode lower seat or the expanding end is internally provided with a plurality of comb-shaped teeth, so that the skin cuticle can be effectively removed through simple rotation, and the comb-shaped electrode lower seat or the expanding end is well and stably anchored on the scalp with hair. The expansion end is also convenient to be filled with water absorbing materials immersed with electrolyte to form a detachable conductive medium unit, and comb teeth can be used for supporting the water absorbing materials to ensure good ion conducting channels, so that the electrode-skin impedance is reduced.
Drawings
Fig. 1 is a schematic diagram of an integrated device for electrical stimulation and electroencephalogram recording, in which an electrical stimulation electrode is fixed on the top of an upper plug-in unit.
Fig. 2 is a schematic diagram of another integrated device for electrical stimulation and electroencephalogram recording, in which the electrode lower seat is in a horn shape.
Fig. 3 is a schematic diagram of another integrated device for electrical stimulation and electroencephalogram recording, wherein a horn-shaped expansion end is arranged at the bottom end of the upper electrode seat.
1-an electroencephalogram recording electrode; 2-electrode upper seat; 3-electrode lower base; 4-a support; 5-an electrical stimulation electrode; 6-a conductive medium; 7-upper plug-in; 8-a horn-shaped expansion end; 9-comb teeth; 10-conductive medium injection hole.
Detailed Description
The invention is described in further detail below with reference to the accompanying drawings.
Example 1: is a basic embodiment of the present invention. As shown in fig. 1, 2 and 3, an integrated device for electrical stimulation and electroencephalography comprises an electroencephalography electrode 1, an electrode upper seat 2, an electrode lower seat 3, a supporting body 4, an electrical stimulation electrode 5, a conductive medium 6 and an upper plug-in unit 7. The electroencephalogram recording electrode 1 is embedded in the electrode upper seat 2. When the electroencephalogram recording electrode 1 is embedded in the electrode lower seat 3, the equivalent embodiment is provided. The electric stimulation electrode 5 is integrally packaged in the upper plug-in 7; the electrode upper seat 2 and the electrode lower seat 3 form an electrode seat, and the electrode seat is arranged on a support body according to an international universal electroencephalogram positioning system (such as 10-20, 10-10 and 10-5); the upper plug-in 7 is fixed on the electrode upper seat 2, and a conductive medium 6 is arranged in the cavity of the upper plug-in. The main advantages are as follows: the device integrates an electroencephalogram recording electrode and an electric stimulation electrode simultaneously, and realizes real-time synchronization of electric stimulation and electroencephalogram recording. The rapid and accurate positioning of the electric stimulation electrode is realized by skillfully utilizing the international universal electroencephalogram positioning systems of 10-20 and the like.
Example 2: is a preferred embodiment of the present invention. As shown in fig. 1, the integrated device for electrical stimulation and electroencephalograph recording comprises an electroencephalograph recording electrode 1, an electrode upper seat 2, an electrode lower seat 3, a supporting body 4, an electrical stimulation electrode 5, a conductive medium 6 and an upper plug-in unit 7. The electroencephalogram recording electrode 1 is embedded in the electrode upper seat 2, and the specific position of the electroencephalogram recording electrode on the electrode upper seat can be flexibly designed according to application. The upper plug-in 7 is provided with a notch on the side facing the electroencephalogram recording electrode 1, so that the conductive medium 6 is contacted with the electroencephalogram recording electrode 1. The electric stimulation electrode 5 is integrally packaged on the top or the inner wall of the upper plug-in unit 7, and is made of silver/silver chloride plating, silver/silver chloride powder or inert conductor materials. The electrode upper seat 2 and the electrode lower seat 3 form an electrode seat, and the electrode seats are arranged on a support body according to an international universal electroencephalogram positioning system of 10-20, 10-10, 10-5 and the like, so that the rapid and accurate positioning of the electric stimulation electrode is realized. The electrode upper seat 2 and the electrode lower seat 3 are detachably connected and fixed on a supporting body (such as a cap, a helmet and a head band) through screw knobs, clamping grooves or extrusion. The electrode upper seat 2 and the electrode lower seat 3 can be fixed on the supporting bodies such as a cap, a helmet and a headband in a non-detachable way through bonding or riveting, the electrode upper seat 2 and the electrode lower seat 3 can be integrally formed electrode seats, and the peripheral supporting bodies are embedded into the electrode upper seat and the electrode lower seat through grooves on the electrode seats, so that the fixing of the integrated electrode on the supporting bodies is realized. The electroencephalogram recording electrode 1 and the electric stimulation electrode 5 are in contact with the conductive medium 6, so that electric stimulation and electroencephalogram signals are effectively transmitted. The electric stimulation electrode 5 is integrally packaged on the upper plug-in unit 7, the upper plug-in unit 7 is an independently replaceable component, and is fixedly arranged on the electrode upper seat 2 through an extrusion groove or a clamping groove, so that later maintenance and replacement are facilitated, and the upper plug-in unit can also be used as a disposable consumable for emergency treatment, infection, pediatric department and other outpatients. When the electric stimulation electrode 5 is a replaceable component and is clamped on the upper plug-in unit 7, the electric stimulation electrode belongs to an equivalent embodiment. The conductive medium 6 is a fluid conductive medium and is selected from one or more of conductive adhesive, conductive paste or conductive liquid. When the upper plug-in 7 is not integrated with a sealing or clamping electric stimulation electrode, the upper plug-in can be used as an electroencephalogram record independently. The top end of the upper insert 7 is provided with a conductive medium injection hole 10, and a fluid conductive medium is injected through the conductive medium injection hole 10. Equivalent embodiments are possible when the conductive medium is a water absorbing material immersed in an electrolyte solution. The water absorbing material is selected from one of sponge, cotton fiber and conductive gel.
Example 3: is a preferred embodiment of the present invention. On the basis of the embodiment 2, as shown in fig. 2, the electrode lower seat 3 is horn-shaped. When the bottom end of the electrode upper seat 2 is provided with a horn-shaped expansion end (fig. 3), the electrode upper seat belongs to another equivalent embodiment. The horn-shaped electrode lower seat or the expansion end can effectively increase the effective contact area between the electrode and the scalp, and effectively reduce the electrode-skin impedance, thereby improving the electrical stimulation effect and the electroencephalogram recording signal quality. The horn-shaped electrode lower seat 3 or the horn-shaped expansion end 8 is internally provided with a plurality of comb-shaped teeth 9, so that the skin cuticle can be effectively removed through simple rotation, and the water absorbing material only containing electrolyte solution can be clamped.
Example 4: is yet another preferred embodiment of the present invention. In examples 2 to 3, the electroencephalographic electrode 1 and the electrostimulation electrode 5 were in contact with the same type of electrolyte (fluid type conductive medium or water absorbing material immersed in an electrolyte solution). Unlike examples 2 to 3, the electroencephalographic electrode 1 and the electrostimulation electrode 5 are respectively in contact with a water-absorbing material immersed in an electrolyte solution and a fluid-like conductive medium. The conductive medium 6 is a fluid conductive medium and is selected from one or more of conductive adhesive, conductive paste or conductive liquid. The water absorbing material is selected from one of sponge, cotton fiber and conductive gel, and the electrolyte solution is one or a combination of more of NaCl, KCl or PBS. The fluid type conductive medium and the water-absorbing material composite type conductive medium immersed with the electrolyte solution can effectively improve the contact between the electric stimulation electrode and the conductive medium, and can effectively avoid the risks that the scalp is stained by using the fluid type conductive medium such as conductive adhesive and the like and the short circuit of the electrode at adjacent sites is caused by the flowing of the conductive medium. Meanwhile, the water absorbing material can effectively absorb the fluid type conductive medium on the upper layer, and the working time of the integrated device is prolonged.
The above-described embodiments of the present invention are merely exemplary of further technical solutions, principles, applications, and effects, etc., and it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the inventive concept of the present invention, which fall within the scope of the present invention. That is, the scope of the claims of the present invention is not limited to the above-described embodiments.
Claims (14)
1. An electrical stimulation and electroencephalogram recording integrated device is characterized in that: comprises an electroencephalogram recording electrode (1), an electrode upper seat (2), an electrode lower seat (3), a supporting body (4), an electric stimulation electrode (5), a conductive medium (6) and an upper plug-in (7); the electroencephalogram recording electrode (1) is embedded in the electrode upper seat (2) or the electrode lower seat (3), and the electric stimulation electrode (5) is integrally packaged in the upper plug-in (7); the electrode upper seat (2) and the electrode lower seat (3) form an electrode seat, and the electrode seat is arranged on the support body (4) according to an international electroencephalogram positioning system; the upper plug-in (7) is fixed on the electrode upper seat (2), and a conductive medium (6) is arranged in the cavity of the upper plug-in.
2. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the upper plug-in (7) is provided with a notch at one side which is opposite to the electroencephalogram recording electrode (1), so that the conductive medium (6) is contacted with the electroencephalogram recording electrode (1).
3. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the upper plug-in (7) is fixed on the electrode upper seat (2) through an extrusion groove or a clamping groove.
4. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the top end of the upper plug-in (7) is provided with a conductive medium injection hole (10); the conductive medium is fluid conductive medium and is injected through a conductive medium injection hole (10).
5. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the conductive medium (6) is a water-absorbing material immersed with electrolyte solution, and the water-absorbing material is selected from one of sponge, cotton fiber and conductive gel.
6. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the electric stimulation electrode (5) is made of silver/silver chloride plating, silver/silver chloride powder or inert conductor material.
7. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the electrode upper seat (2) and the electrode lower seat (3) are detachably connected and fixed on the support body through screw knob, clamping groove or extrusion; or is undetachable and is fixed on the support body (4) in a riveting or bonding way; or is an integrally formed whole.
8. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the top or the inner wall of the upper plug-in (7) is fixed with an electric stimulation electrode (5).
9. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the supporting body (4) is one of a hat, a helmet and a headband.
10. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the conductive medium contacted with the electroencephalogram recording electrode (1) and the electric stimulation electrode (5) is a fluid conductive medium or a water absorbing material immersed with electrolyte solution.
11. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the electroencephalogram recording electrode (1) and the electric stimulation electrode (5) are respectively contacted with a water absorbing material immersed with electrolyte solution and a fluid-shaped conductive medium.
12. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the electrode lower seat (3) is in a horn shape.
13. The integrated electrical stimulation and electroencephalography device according to claim 1, wherein: the bottom end of the electrode upper seat (2) is provided with a horn-shaped expansion end (8).
14. The integrated electrical stimulation and electroencephalography device according to claim 12 or 13, wherein: a plurality of comb-shaped teeth (9) are arranged in the electrode lower seat (3) or the expansion end.
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