CN116328016A - Novel self-pressure-measuring balloon catheter - Google Patents

Novel self-pressure-measuring balloon catheter Download PDF

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Publication number
CN116328016A
CN116328016A CN202310352902.0A CN202310352902A CN116328016A CN 116328016 A CN116328016 A CN 116328016A CN 202310352902 A CN202310352902 A CN 202310352902A CN 116328016 A CN116328016 A CN 116328016A
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film
membrane
chitosan hydrogel
balloon catheter
novel self
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Chinese (zh)
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王春飞
田琼
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Seventh Affiliated Hospital Of Sun Yat Sen University Shenzhen
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Seventh Affiliated Hospital Of Sun Yat Sen University Shenzhen
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Priority to CN202310352902.0A priority Critical patent/CN116328016A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/26Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/46Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
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    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/204Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
    • A61L2300/208Quaternary ammonium compounds
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    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/232Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402Anaestetics, analgesics, e.g. lidocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
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    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The invention belongs to the technical field of medical supplies, and particularly relates to a novel self-pressure-measuring air sac catheter which comprises a back lining, wherein a chitosan hydrogel film is adhered to the lower part of the back lining, an antibacterial tridecapeptide film is adhered to the lower part of the chitosan hydrogel film, a high-molecular quaternary ammonium salt film is adhered to the lower part of the antibacterial tridecapeptide film, and a fentanyl film is adhered to the lower part of the high-molecular quaternary ammonium salt film. This novel self-pressure balloon catheter has antibacterial, analgesic, hemostatic performance through setting up chitosan hydrogel membrane layer, can effectively prevent the red swelling phenomenon that the venous indwelling needle led to because of the infection, can reduce the painful sense of puncture position simultaneously. In addition, the transparent dressing with high air permeability does not cause skin whitening phenomenon, and simultaneously has low sensitization, thus bringing excellent comfort to patients; wherein the chitosan hydrogel film and the polyurethane film coated with medical gel are designed into round corners, so that the pasting is firmer.

Description

Novel self-pressure-measuring balloon catheter
Technical Field
The invention relates to the technical field of medical supplies, in particular to a novel self-pressure-measuring balloon catheter.
Background
Early esophageal cancer endoscopic treatments included endoscopic resective and non-resective treatments. Endoscopic resection includes endoscopic submucosectomy, polycyclic ligation submucosectomy, endoscopic submucosal dissection, endoscopic submucosal tunnel dissection, and the like.
However, the catheter does not have bacteriostasis, so that nursing staff is required to replace the catheter frequently when red swelling, pain and bacterial infection occur at the puncture part of the venous indwelling needle, and meanwhile, the skin around the needle eye is required to be strictly disinfected with iodine and alcohol every day. This not only increases the workload of the caregivers, but also causes psychological anxiety and physical pain to the patients due to bacterial infection and inflammation, so a novel self-pressure balloon catheter is needed.
Disclosure of Invention
Based on the prior art, the invention provides a novel self-pressure-measuring balloon catheter, which aims to solve the problems that a transparent dressing in the prior art does not have bacteriostasis, analgesic property and hemostatic property, and when a venous indwelling needle causes infection of a puncture part, the nursing staff workload and discomfort of a patient are increased due to inflammation.
The novel self-pressure-measuring air bag catheter comprises a back lining, wherein a chitosan hydrogel film is adhered to the lower side of the back lining, an antibacterial tridecapeptide film is adhered to the lower side of the chitosan hydrogel film, a high-molecular quaternary ammonium salt film is adhered to the lower side of the antibacterial tridecapeptide film, a fentanyl film is adhered to the lower side of the high-molecular quaternary ammonium salt film, a medical adhesive-coated polyurethane film is arranged below the fentanyl film, and a transparent back lining is adhered to the lower side of the medical adhesive-coated polyurethane film.
Preferably, the back lining is a silicon paper back lining, the middle of the silicon paper back lining is of a rectangular structure, the two ends of the silicon paper back lining are of arc structures, the length of the silicon paper back lining is 5-20cm, the width of the silicon paper back lining is 2-15cm, and the arc radius of the silicon paper back lining is 1-10cm.
Preferably, the thickness of the chitosan hydrogel film is 0.03-0.1mm, the middle of the chitosan hydrogel film and the polyurethane film coated with the medical gel are both rectangular structures, and the two ends of the chitosan hydrogel film and the polyurethane film coated with the medical gel are arc structures.
Preferably, the chitosan hydrogel film is located in the middle of the medical gel-coated polyurethane film and has an area smaller than that of the medical gel-coated polyurethane film.
Preferably, the polyurethane film coated with the medical gel is a commercially available high-permeability Shu Shi or IV3000 film with a thickness of 0.01-0.03mm.
Preferably, the medical gel on the polyurethane film coated with the medical gel is hypoallergenic alpha-cyanoacrylate.
Preferably, the transparent backing is a PE film or a PET film.
Preferably, the external dimensions of the antibacterial tridecapeptide film, the high-molecular quaternary ammonium salt film and the fentanyl film are matched with the external dimensions of the chitosan hydrogel film.
Preferably, the antibacterial tridecapeptide film, the high molecular quaternary ammonium salt film and the fentanyl film are all heavy and overlapped with the chitosan hydrogel film.
Preferably, the antibacterial tridecapeptide film is made of antibacterial tridecapeptide, the polymer quaternary ammonium salt film is made of polymer quaternary ammonium salt, and the fentanyl film is made of fentanyl.
The beneficial effects of the invention are as follows:
1. the invention has simple structure, good treatment effect and convenient use; the workload of nursing staff can be reduced, and the satisfaction degree of patients can be improved.
2. Through setting up chitosan hydrogel membrane layer and having antibacterial, analgesic, hemostatic performance, can effectively prevent the red swelling phenomenon that the venous indwelling needle led to because of the infection, can reduce the painful sense of puncture position simultaneously. In addition, the transparent dressing with high air permeability does not cause skin whitening phenomenon, and simultaneously has low sensitization, thus bringing excellent comfort to patients; wherein the chitosan hydrogel film and the polyurethane film coated with medical gel are designed into round corners, so that the pasting is firmer.
3. Antibacterial and anti-inflammatory effects are achieved by arranging antibacterial tridecapeptide films, so that wound healing is promoted, skin barriers are repaired, and skin and mucous membrane immunity is improved; the preparation method has the effects of inhibiting the growth of skin bacteria, treating acne, dermatitis, skin damage and other diseases, reducing scar formation, repairing skin barriers, preventing wound infection and promoting wound healing, and the macromolecular quaternary ammonium salt membrane is arranged to perform ion exchange with Ca < 2+ >, mg < 2+ > and the like near cell membranes by means of N < + >, so that the charge balance in bacteria is destroyed to cause bacterial death, further the antibacterial effect is achieved, and the effect of wound pain relieving is achieved after the fentanyl membrane is arranged for needle insertion.
Drawings
FIG. 1 is a schematic illustration of a novel self-pressure balloon catheter;
fig. 2 is an exploded view of a novel self-pressure balloon catheter.
In the figure: 1. a backing; 2. a chitosan hydrogel film; 3. an antibacterial tridecapeptide membrane; 4. a polymer quaternary ammonium salt film; 5. a fentanyl film; 6. polyurethane film coated with medical glue; 7. a transparent backing.
Description of the embodiments
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
Referring to fig. 1-2, a novel self-pressure-measuring balloon catheter comprises a backing 1, wherein the backing 1 is a silicon paper backing 1, the middle of the silicon paper backing 1 is of a rectangular structure, two ends of the silicon paper backing are of arc structures, the length of the silicon paper backing is 5-20cm, the width of the silicon paper backing is 2-15cm, and the arc radius of the silicon paper backing is 1-10cm.
The chitosan hydrogel film 2 is adhered below the back lining 1, the thickness of the chitosan hydrogel film 2 is 0.03-0.1mm, and the chitosan hydrogel film 2 is composed of a mixture of chitosan and glycerol.
An antibacterial tridecapeptide film 3 is adhered below the chitosan hydrogel film 2, and antibacterial and anti-inflammatory effects are achieved by arranging the antibacterial tridecapeptide film 3, so that wound healing is promoted, skin barriers are repaired, and skin and mucous membrane immunity is improved; has effects of inhibiting bacterial growth on skin, treating acne, dermatitis, skin injury, etc., reducing scar formation, repairing skin barrier, preventing wound infection, and promoting wound healing.
A polymer quaternary ammonium salt film 4 is adhered below the antibacterial tridecapeptide film 3, and the polymer quaternary ammonium salt film 4 is arranged to perform ion exchange with Ca2+, mg2+ and the like near a cell membrane by virtue of N+ to destroy charge balance in bacteria so as to kill bacteria, thereby playing an antibacterial role.
The fentanyl film 5 is adhered to the lower part of the high-molecular quaternary ammonium salt film 4, and the external dimensions of the antibacterial trideceth film 3, the high-molecular quaternary ammonium salt film 4 and the fentanyl film 5 are matched with the external dimensions of the chitosan hydrogel film 2; the antibacterial tridecapeptide film 3, the high molecular quaternary ammonium salt film 4 and the fentanyl film 5 are overlapped with the chitosan hydrogel film 2; the antibacterial tridecapeptide membrane 3 is made of antibacterial tridecapeptide, the polymer quaternary ammonium salt membrane 4 is made of polymer quaternary ammonium salt, and the fentanyl membrane 5 is made of fentanyl; the fentanyl film 5 was provided for wound pain relieving effect after needle insertion.
A polyurethane film 6 coated with medical gel is arranged below the fentanyl film 5, the middle parts of the chitosan hydrogel film 2 and the polyurethane film 6 coated with medical gel are both rectangular structures, and both ends are arc structures; the chitosan hydrogel film 2 is positioned in the middle of the polyurethane film 6 coated with the medical gel and has an area smaller than that of the polyurethane film 6 coated with the medical gel; the polyurethane film 6 coated with medical adhesive is commercial Shu Shi 3000 or IV3000 with high air permeability, the thickness is 0.01-0.03mm, the holding viscosity of the adhesive-coated part is less than or equal to 2.5cm or does not fall off within 30min, and the peeling strength of the self-adhesive-coated part is more than or equal to 1.0N/cm.
The medical glue on the polyurethane film 6 coated with the medical glue is hypoallergenic alpha-cyanoacrylate.
A transparent back lining 7 is adhered below the polyurethane film 6 coated with the medical adhesive, and the transparent back lining 7 is a PE film or a PET film.
The application range is as follows: the invention is mainly used for fixing the catheter: a venous indwelling needle, a peripheral and central venous catheter of the PICC are fixed, a central venous jugular vein of the CVC is fixed, a subclavian femoral venous catheter is fixed, and a subcutaneous transfusion port catheter is fixed; fixing the secondary dressing; protection of puncture sites and wound care.
The using method comprises the following steps: opening the inner packaging bag by conventional debridement and aseptic operation, taking out the product, tearing off the back lining 1, tightly attaching the product to the puncture part, slightly pressing for about 1 min to ensure that the application on the wound surface is more firmly combined, and finally tearing off the transparent back lining 7; if the puncture part is moist, loose and polluted, the puncture part needs to be replaced in time; the product has been sterilized to meet the requirement of sterility, and secondary pollution should be avoided during use.
The bacteriostasis and hemostasis principle of the product: the chitosan has active amino group, which can combine with negatively charged substances in bacteria such as milk protein and nucleic acid to affect the normal physiological function of cells and death, or adsorb on the surface of bacteria cells to form a layer of polymer film, which causes the permeability to change and causes cell death. In addition, the active amino group can aggregate red blood cells, concentrate platelets and realize the hemostatic function without depending on the conventional blood coagulation way.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.

Claims (10)

1. A novel self-pressure balloon catheter, characterized in that: including backing (1), the below of backing (1) bonds there is chitosan hydrogel membrane (2), the below of chitosan hydrogel membrane (2) bonds there is antibiotic tridecyl peptide membrane (3), the below of antibiotic tridecyl peptide membrane (3) bonds there is polymer quaternary ammonium salt membrane (4), the below of polymer quaternary ammonium salt membrane (4) bonds there is fentanyl membrane (5), the below of fentanyl membrane (5) is provided with polyurethane membrane (6) that scribbles medical glue, the below of polyurethane membrane (6) that scribbles medical glue bonds there is transparent back lining (7).
2. A novel self-pressure balloon catheter according to claim 1, wherein: the back lining (1) is a silicon paper back lining, the middle of the silicon paper back lining is of a rectangular structure, the two ends of the silicon paper back lining are of arc structures, the length of the silicon paper back lining is 5-20cm, the width of the silicon paper back lining is 2-15cm, and the arc radius of the silicon paper back lining is 1-10cm.
3. A novel self-pressure balloon catheter according to claim 1, wherein: the thickness of the chitosan hydrogel film (2) is 0.03-0.1mm, the middle parts of the chitosan hydrogel film (2) and the polyurethane film (6) coated with medical gel are rectangular structures, and the two ends of the chitosan hydrogel film are arc structures.
4. A novel self-pressure balloon catheter according to claim 1, wherein: the chitosan hydrogel film (2) is positioned in the middle of the polyurethane film (6) coated with medical gel, and the area of the chitosan hydrogel film is smaller than that of the polyurethane film (6) coated with medical gel.
5. A novel self-pressure balloon catheter according to claim 1, wherein: the polyurethane film (6) coated with the medical adhesive is a commercial Shu Shi 3000 or IV3000 film with high air permeability, and the thickness of the polyurethane film is 0.01-0.03mm.
6. A novel self-pressure balloon catheter according to claim 1, wherein: the medical adhesive on the polyurethane film (6) coated with the medical adhesive is hypoallergenic alpha-cyanoacrylate.
7. A novel self-pressure balloon catheter according to claim 1, wherein: the transparent back lining (7) is PE film or PET film.
8. A novel self-pressure balloon catheter according to claim 1, wherein: the external dimensions of the antibacterial tridecapeptide film (3), the high-molecular quaternary ammonium salt film (4) and the fentanyl film (5) are matched with the external dimensions of the chitosan hydrogel film (2).
9. A novel self-pressure balloon catheter according to claim 1, wherein: the antibacterial tridecapeptide film (3), the high-molecular quaternary ammonium salt film (4) and the fentanyl film (5) are overlapped with the chitosan hydrogel film (2).
10. A novel self-pressure balloon catheter according to claim 1, wherein: the antibacterial tridecapeptide membrane (3) is made of antibacterial tridecapeptide, the polymer quaternary ammonium salt membrane (4) is made of polymer quaternary ammonium salt, and the fentanyl membrane (5) is made of fentanyl.
CN202310352902.0A 2023-04-04 2023-04-04 Novel self-pressure-measuring balloon catheter Pending CN116328016A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101284147A (en) * 2008-06-06 2008-10-15 四川大学华西医院 Sustained-release analgesia medical dressing and preparation method thereof
CN204319351U (en) * 2014-12-11 2015-05-13 南阳市汇博生物技术有限公司 A kind of medical composite aquogel dressing
CN204446300U (en) * 2015-02-03 2015-07-08 广东泰宝医疗科技股份有限公司 A kind of composite medical dressing
CN107429029A (en) * 2015-04-06 2017-12-01 3M创新有限公司 Removable film forming gel composition and its application process
CN109106979A (en) * 2018-09-11 2019-01-01 吉林省蓝鼎陆和科技有限公司 A kind of tridecanoic peptide antiseptic dressing and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101284147A (en) * 2008-06-06 2008-10-15 四川大学华西医院 Sustained-release analgesia medical dressing and preparation method thereof
CN204319351U (en) * 2014-12-11 2015-05-13 南阳市汇博生物技术有限公司 A kind of medical composite aquogel dressing
CN204446300U (en) * 2015-02-03 2015-07-08 广东泰宝医疗科技股份有限公司 A kind of composite medical dressing
CN107429029A (en) * 2015-04-06 2017-12-01 3M创新有限公司 Removable film forming gel composition and its application process
CN109106979A (en) * 2018-09-11 2019-01-01 吉林省蓝鼎陆和科技有限公司 A kind of tridecanoic peptide antiseptic dressing and preparation method thereof

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