CN116327433A

CN116327433A - Artificial valve device

Info

Publication number: CN116327433A
Application number: CN202111590803.3A
Authority: CN
Inventors: 潘孔荣; 张存义; 仪克晶; 刘鹏忠; 张一�
Original assignee: Peijia Medical Technology Suzhou Co ltd
Current assignee: Peijia Medical Technology Suzhou Co ltd
Priority date: 2021-12-23
Filing date: 2021-12-23
Publication date: 2023-06-27

Abstract

The invention relates to the technical field of medical appliances, and discloses a prosthetic valve device. The first end of the first mesh unit and the first end of the second mesh unit of the prosthetic valve device are spaced apart from each other in a preset direction, and the second end of the first mesh unit and the second end of the second mesh unit are spaced apart from each other in the preset direction. According to the invention, the ends of the first mesh unit and the second mesh unit are spaced from each other in the preset direction, so that the ends of the first mesh unit and the second mesh unit are staggered from each other in the preset direction, which is beneficial to reducing the limit diameter size of the compressed artificial valve device, namely the artificial valve device can be compressed to a smaller diameter size, and further is beneficial to reducing the sheath inserting difficulty of the artificial valve device.

Description

Artificial valve device

Technical Field

The invention relates to the technical field of medical appliances, in particular to a prosthetic valve device.

Background

The aortic valve is a tri-leaflet valve that is positioned between the left ventricular outflow tract and the ascending aorta. The primary function of the valve is to maintain effective left ventricular ejection. Valves are affected under many pathological conditions, and various abnormalities occur. Aortic valve disease is a relatively common disease in the clinical work of cardiology and cardiac surgeons, mainly due to its high incidence in the elderly population. Methods of treating severe aortic valve disorders include valve surgical repair or replacement surgery, and the like. Standard surgical treatment strategies include aortic valve repair, valve protection techniques, aortic valve replacement techniques, and the like.

Aortic valve disorders include aortic stenosis, aortic insufficiency, and the like, both of which coexist in most cases. Aortic stenosis accounts for the majority of aortic disease, with a 1-2% incidence in people older than 65 years and a 4% incidence in people older than 85 years.

The technical principle of transcatheter aortic valve replacement (Transcatheter Aortic Valve Replacement, TAVR) is to compress and load a stent-graft with a prosthetic valve sewn thereto into a delivery system, then deliver it along an approach (e.g., an artery) to the aortic valve and release it, squeeze the diseased aortic valve aside the prosthetic valve, which is secured to the aortic valve, and replace the diseased aortic valve.

However, the current prosthetic valve stent is still large in the limit diameter size after being compressed due to unreasonable structural design, so that the prosthetic valve stent is inconvenient to load into a conveying system, and the operation is not facilitated.

Disclosure of Invention

In view of the above, the present invention mainly solves the technical problem of providing a prosthetic valve device capable of reducing the limit diameter size of the prosthetic valve device after compression.

In order to solve the technical problems, the invention adopts a technical scheme that: a prosthetic valve device is provided. The prosthetic valve device includes a stent having a blood flow inflow end and a blood flow outflow end disposed opposite to each other in a predetermined direction. The support comprises a plurality of mesh structure layers distributed layer by layer along a preset direction, at least part of mesh structure layers are target mesh structure layers, each target mesh structure layer comprises a first mesh unit and a second mesh unit, the first mesh unit and the second mesh unit are adjacent to each other in the preset circumferential direction, and the preset direction is perpendicular to a plane defined by the preset circumferential direction. The first mesh unit and the second mesh unit each have a first end facing the inflow end of the blood flow and a second end facing the outflow end of the blood flow, the first ends of the first mesh unit and the second mesh unit are spaced apart from each other in a preset direction, and the second ends of the first mesh unit and the second mesh unit are spaced apart from each other in the preset direction. The prosthetic valve device also includes a valve coupled to the stent.

In one embodiment of the invention, the first end of the first mesh unit is adjacent to the blood flow inflow end relative to the first end of the second mesh unit, and the second end of the first mesh unit is adjacent to the blood flow inflow end relative to the second end of the second mesh unit.

In one embodiment of the invention, the mesh layer adjacent to the target mesh layer is connected to the first end of the first mesh unit or to the second end of the second mesh unit.

In one embodiment of the invention, the valve is sutured to the stent through the first mesh unit when the mesh layer adjacent to the target mesh layer is connected to the first end of the first mesh unit; and when the mesh layer adjacent to the target mesh layer is connected to the second end of the second mesh unit, the valve is sutured to the stent through the second mesh unit.

In one embodiment of the invention, the first end of the first mesh unit is adjacent to the inflow end of the blood stream relative to the first end of the second mesh unit, and the second end of the first mesh unit is adjacent to the outflow end of the blood stream relative to the second end of the second mesh unit.

In an embodiment of the present invention, a mesh structure layer adjacent to a target mesh structure layer includes a connection portion and at least two support rod portions, the at least two support rod portions are sequentially and alternately distributed along a preset circumferential direction, and a connection portion is disposed between any two adjacent support rod portions; the support rod part is connected with the first mesh unit, and the connecting part is sunken towards the target mesh structure layer.

In an embodiment of the invention, the connecting part comprises a first connecting rod part and a second connecting rod part, the first connecting rod part is connected with the second connecting rod part, the first connecting rod part is also connected with the supporting rod part at one side of the connecting part, and the second connecting rod part is also connected with the supporting rod part at the other side of the connecting part; the length of the first connecting rod part and the length of the second connecting rod part are smaller than the length of the supporting rod part.

In an embodiment of the present invention, a mesh structure layer adjacent to a target mesh structure layer includes a connection portion and at least two support rod portions, the at least two support rod portions are sequentially and alternately distributed along a preset circumferential direction, and a connection portion is disposed between any two adjacent support rod portions; the support rod part is connected with the second mesh unit, and the connecting part protrudes towards the direction deviating from the target mesh structure layer.

In one embodiment of the present invention, the mesh layer adjacent to the target mesh layer includes a connection portion; any two adjacent first mesh units are connected through a connecting part.

In one embodiment of the present invention, the mesh structure layer includes at least two mesh units sequentially distributed along a predetermined circumferential direction; the mesh cell density of the mesh layer near the outflow end of the blood stream is greater than the mesh cell density of the mesh layer near the inflow end of the blood stream.

The beneficial effects of the invention are as follows: unlike the prior art, the present invention provides a prosthetic valve device. The prosthetic valve device includes a stent including a plurality of mesh layers distributed layer-by-layer along a predetermined direction. At least a portion of the mesh layer is a target mesh layer, the first and second mesh units of the target mesh layer each having a first end facing the inflow end of the blood stream and a second end facing the outflow end of the blood stream.

The first ends of the first and second mesh units are spaced apart from each other in a preset direction, and the second ends of the first and second mesh units are spaced apart from each other in the preset direction. Because the end parts of the first mesh unit and the second mesh unit are larger than the other positions of the first mesh unit and the second mesh unit after the stent is compressed, the ends of the first mesh unit and the second mesh unit are arranged to be spaced from each other in the preset direction, so that the ends of the first mesh unit and the second mesh unit are staggered from each other in the preset direction, the limit diameter size of the compressed artificial valve device is reduced, namely the artificial valve device can be compressed to a smaller diameter size, and the sheath inserting difficulty of the artificial valve device is reduced.

Drawings

The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the invention and together with the description, serve to explain the principles of the invention. Furthermore, these drawings and the written description are not intended to limit the scope of the inventive concept in any way, but to illustrate the inventive concept to those skilled in the art by referring to the specific embodiments.

FIG. 1 is a schematic view of one embodiment of a prosthetic valve device of the present invention;

FIG. 2 is a schematic view of the structure of a first embodiment of the bracket of the present invention;

FIG. 3 is a schematic view of the structure of the stent of the present invention in a compressed state;

FIG. 4 is a schematic view of the expanded configuration of the stent of FIG. 2;

FIG. 5 is a schematic view of a second embodiment of the stent of the present invention in an expanded configuration;

FIG. 6 is a schematic view of a third embodiment of a stent of the present invention in an expanded configuration;

fig. 7 is a schematic view of a fourth embodiment of the stent of the present invention in an expanded configuration.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the present invention more apparent, the technical solutions in the embodiments of the present invention will be clearly and completely described in the following in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention. The following embodiments and features of the embodiments may be combined with each other without conflict.

In order to solve the technical problem of larger diameter size of the compressed artificial valve stent in the prior art, an embodiment of the present invention provides an artificial valve device. The prosthetic valve device includes a stent having a blood flow inflow end and a blood flow outflow end disposed opposite to each other in a predetermined direction. The support comprises a plurality of mesh structure layers distributed layer by layer along a preset direction, at least part of mesh structure layers are target mesh structure layers, each target mesh structure layer comprises a first mesh unit and a second mesh unit, the first mesh unit and the second mesh unit are adjacent to each other in the preset circumferential direction, and the preset direction is perpendicular to a plane defined by the preset circumferential direction. The first mesh unit and the second mesh unit each have a first end facing the inflow end of the blood flow and a second end facing the outflow end of the blood flow, the first ends of the first mesh unit and the second mesh unit are spaced apart from each other in a preset direction, and the second ends of the first mesh unit and the second mesh unit are spaced apart from each other in the preset direction. The prosthetic valve device also includes a valve coupled to the stent. The details are set forth below.

Referring to fig. 1, fig. 1 is a schematic view of an embodiment of a prosthetic valve device according to the present invention.

In one embodiment, the prosthetic valve device may be applied to transcatheter aortic valve replacement or the like, and may specifically be compressed and loaded into a delivery system, then delivered along an approach to and released from the aortic valve, causing the prosthetic valve device to expand to squeeze the diseased aortic valve aside the prosthetic valve device, thereby anchoring the prosthetic valve device at the aortic valve, replacing the diseased aortic valve.

Specifically, the prosthetic valve device includes a stent 10 and a valve 20. The stent 10 is used to anchor the valve 20 to the lesion. To accommodate transcatheter aortic valve replacement, the present embodiment stent 10 is capable of a compressed and expanded configuration, i.e., the present embodiment stent 10 is allowed to be compressed to load into the delivery system and allowed to expand at the patient site such that the stent 10 is anchored to the patient site. The valve 20 is attached to the stent 10, and the valve 20 can be anchored with the stent 10 to the lesion to replace the diseased aortic valve.

Further, the valve 20 may be attached to the stent 10 by suturing, welding, or the like. The stent 10 may be provided with fixation holes through which the valve 20 is connected to the stent 10. Of course, in other embodiments of the invention, the valve 20 may be directly attached to the stent 10 without the stent 10 being provided with fixation holes.

Referring to fig. 2, fig. 2 is a schematic structural view of a first embodiment of the bracket according to the present invention.

In one embodiment, the stent 10 has a blood inflow end a and a blood outflow end B, which are disposed opposite to each other in a predetermined direction (as indicated by an arrow X in fig. 2, the same applies hereinafter).

The stent 10 includes a plurality of mesh layers (including a first mesh layer, a second mesh layer, and the like, hereinafter) distributed layer by layer in a predetermined direction. At least part of the mesh layer is a target mesh layer comprising a first mesh unit 31 and a second mesh unit 32. The first mesh units 31 and the second mesh units 32 are distributed along a preset circumferential direction (as indicated by arrow O in fig. 2, the same applies hereinafter), and the first mesh units 31 and the second mesh units 32 are adjacent to each other in the preset circumferential direction, wherein the preset direction is perpendicular to a plane defined by the preset circumferential direction.

Referring to fig. 3, the end 10B of the mesh unit 10a of the stent 10 facing the blood inflow end a and the blood outflow end B (fig. 3 exemplarily shows that the end 10B faces the blood inflow end a) generally maintains a certain curvature after the stent 10 is compressed, that is, the end 10B of the mesh unit 10a cannot be compressed to a limit state. This limit state means that the rod portions 10c on both sides of the end portion 10b of the mesh unit 10a are closely adhered together. However, if the end portion 10b of the mesh unit 10a has a certain curvature, it means that the rod portions 10c at both sides of the end portion 10b of the mesh unit 10a cannot be tightly attached together, which means that the length of the end portion 10b of the mesh unit 10a in the above-mentioned predetermined circumferential direction is large, and typically reaches 0.8mm. While the mesh unit 10a may be compressed to a limited state at other positions than the end portion 10b, its length in the above-mentioned preset circumferential direction may be compressed to a smaller size, and may be typically compressed to 0.6mm. In other words, after the stent 10 is compressed, the end 10b of the mesh unit 10a may be larger in size than the other positions of the mesh unit 10a except for the end 10 b.

The first mesh unit 31 and the second mesh unit 32 of the present embodiment each have a first end facing the blood flow inflow end a and a second end facing the blood flow outflow end B. Specifically, the first mesh unit 31 has a first end 311 and a second end 312, and the second mesh unit 32 has a first end 321 and a second end 322. The first ends 311 and 321 of the first and second mesh units are spaced apart from each other in a preset direction, and the second ends 312 and 322 of the first and second mesh units are spaced apart from each other in a preset direction. The end portions corresponding to the first mesh unit 31 and the second mesh unit 32 are arranged to be spaced from each other in the preset direction, so that the end portions corresponding to the first mesh unit 31 and the second mesh unit 32 are staggered from each other in the preset direction, which is beneficial to reducing the limit diameter size of the compressed artificial valve device, namely, the artificial valve device can be compressed to a smaller diameter size, and further is beneficial to reducing the sheathing difficulty of the artificial valve device.

Referring to fig. 2 and 4, fig. 4 is a schematic view of the stent shown in fig. 2 in an expanded configuration.

In one embodiment, the first end 311 of the first mesh unit is proximate to the blood flow inflow end A relative to the first end 321 of the second mesh unit, and the second end 312 of the first mesh unit is also proximate to the blood flow inflow end A relative to the second end 322 of the second mesh unit.

In the above manner, when the other mesh structure layer is connected to the side of the target mesh structure layer close to the blood inflow end a, as shown in fig. 4, the first end 321 of the second mesh unit can be far away from the other mesh structure layer, so that interference and collision between the first end 321 of the second mesh unit and the other mesh structure layer after the stent 10 is compressed can be avoided; and when one side of the target mesh structure layer away from the blood inflow end A is connected with other mesh structure layers, the second end 312 of the first mesh unit can be away from the other mesh structure layers, so that interference and collision between the second end 312 of the first mesh unit and the other mesh structure layers after the stent 10 is compressed can be avoided, the risk of abrasion of the stent 10 caused by structural interference is reduced, and the overall reliability of the stent 10 is guaranteed.

Further, the mesh layer adjacent to the target mesh layer is connected to the first end 311 of the first mesh unit or to the second end 322 of the second mesh unit.

When the mesh structure layer adjacent to the target mesh structure layer is connected to the first end 311 of the first mesh unit, as shown in fig. 4, the mesh structure layer is made to avoid the first end 321 of the second mesh unit, so that interference and collision between the first end 321 of the second mesh unit and the mesh structure layer after the stent 10 is compressed can be avoided; and when the second end 322 of the second mesh unit is connected to the mesh structure layer adjacent to the target mesh structure layer, the mesh structure layer is enabled to avoid the second end 312 of the first mesh unit, so that interference and collision between the second end 312 of the first mesh unit and the mesh structure layer after the stent 10 is compressed can be avoided, the risk of abrasion of the stent 10 caused by structural interference is reduced, and the overall reliability of the stent 10 is guaranteed.

Further, in the case where the valve is connected to the stent 10 by sewing, when the mesh layer adjacent to the target mesh layer is connected to the first end 311 of the first mesh unit, as shown in fig. 4, the first mesh unit 31 has a superior rigidity and can perform a superior supporting function. The valve is connected to the stent 10 by the first mesh unit 31 so that the valve can be stably supported to the stent 10. Preferably, the valve is attached to the stent 10 by means of the first mesh unit 31, e.g. the valve is sutured to the stent 10 by means of the first mesh unit 31, wherein at least part of the first mesh unit 31 acts as fixation hole.

And when the mesh layer adjacent to the target mesh layer is connected to the second end 322 of the second mesh unit, the second mesh unit 32 has better rigidity and can perform good supporting function. The valve is connected to the stent 10 by the second mesh unit 32 so that the valve can be stably supported to the stent 10. Preferably, the valve is attached to the stent 10 by the second mesh unit 32, e.g. the valve is sutured to the stent 10 by the second mesh unit 32, at least part of the second mesh unit 32 then acting as fixation holes.

It should be noted that, in the case where the first end 311 of the first mesh unit is close to the blood inflow end a relative to the first end 321 of the second mesh unit and the second end 312 of the first mesh unit is also close to the blood inflow end a relative to the second end 322 of the second mesh unit in this embodiment, the target mesh structure layer may be located at the blood inflow end a (not shown) or the blood outflow end B (as shown in fig. 4), that is, the target mesh structure layer is close to the blood inflow end a or the blood outflow end B compared to other mesh structure layers of the stent 10, which is not limited herein.

With continued reference to fig. 4, in an exemplary embodiment, the stent 10 includes a first mesh layer 11 and a second mesh layer 12. The first mesh layer 11 and the second mesh layer 12 are disposed in this order in a direction from the blood flow outflow end B toward the blood flow inflow end a.

The first mesh layer 11 in this embodiment is the target mesh layer described in the above embodiment. The second mesh layer 12 also includes at least two mesh units sequentially distributed along a predetermined circumferential direction. The mesh units of the second mesh layer 12 are connected to the first ends 311 of the first mesh units of the first mesh layer 11.

The mesh unit density of the mesh structure layer near the blood flow outflow end B is greater than the mesh unit density of the mesh structure layer near the blood flow inflow end a. The mesh unit density of the first mesh layer 11 is greater than that of the second mesh layer 12 in this embodiment. In other words, the expansion amount of the mesh units in the first mesh structure layer 11 along with the expansion of the stent 10 is smaller, the rigidity of the mesh units in the first mesh structure layer 11 is smaller, the first mesh structure layer 11 is beneficial to forming a horn-shaped structure after the expansion of the stent 10, and then the affected part is effectively plugged, and the paravalvular leakage is beneficial to preventing.

Referring to fig. 5, fig. 5 is a schematic view showing an expanded structure of a second embodiment of the stent of the present invention.

In one embodiment, the first end 311 of the first mesh unit is adjacent to the blood flow inflow end A relative to the first end 321 of the second mesh unit, and the second end 312 of the first mesh unit is adjacent to the blood flow outflow end B relative to the second end 322 of the second mesh unit. Further, the first mesh unit 31 is connected to the middle position of the second mesh unit 32 in the preset direction at the middle position in the preset direction.

In the above manner, the second mesh unit 32 does not substantially affect the length of the stent 10 in the preset direction, and the length of the first mesh unit 31 in the preset direction is greater than the length of the second mesh unit 32 in the preset direction, i.e., the length of the first mesh unit 31 in the preset direction is greater. In this way, along with the expansion and compression of the stent 10, the length change of the first mesh unit 31 in the preset direction is smaller, so that the change of the axial (i.e. the preset direction) length of the stent 10 in the expansion process is smaller, which is beneficial to ensuring that the prosthetic valve device of the embodiment has good axial positioning performance, ensuring that the stent 10 is accurately anchored at the affected part, reducing the risk of the stent 10 deviating from the affected part, and thus, the embodiment can improve the axial positioning performance of the prosthetic valve device.

Further, the mesh structure layer adjacent to the target mesh structure layer includes a connection portion 13 and at least two support rod portions 14, the at least two support rod portions 14 are sequentially spaced apart along a predetermined circumferential direction, and the connection portion 13 is disposed between any two adjacent support rod portions 14.

With continued reference to fig. 5, in an exemplary embodiment, the stent 10 includes a first mesh layer 11 and a second mesh layer 12. The first mesh layer 11 and the second mesh layer 12 are disposed in this order in a direction from the blood flow outflow end B toward the blood flow inflow end a. The second mesh layer 12 in this embodiment is the target mesh layer described in the above embodiment. The first mesh layer 11 includes the connection portion 13 and the at least two support bar portions 14.

The support rod portion 14 is connected to the first mesh unit 31, and at this time, there is a sufficient space between the connection portion 13 and the second mesh unit 32, so that the connection portion 13 protrudes toward the target mesh structure layer, and the connection portion 13 does not interfere with the second mesh unit 32 even after the stent 10 is compressed. Meanwhile, when the stent 10 is expanded, the connecting portion 13 does not cause the length of the stent 10 in the preset direction to change, that is, the embodiment can reduce the change amount of the axial length of the stent 10 in the expansion process, which is favorable for ensuring that the artificial valve device of the embodiment has good axial positioning performance, ensuring that the stent 10 is accurately anchored at the affected part, reducing the risk of the stent 10 deviating from the affected part, and therefore, the embodiment can improve the axial positioning performance of the artificial valve device.

Further, the connection portion 13 includes a first connection rod portion 131 and a second connection rod portion 132. The first connecting rod portion 131 is connected to the second connecting rod portion 132, and the first connecting rod portion 131 is further connected to the supporting rod portion 14 on one side of the connecting portion 13, and the second connecting rod portion 132 is further connected to the supporting rod portion 14 on the other side of the connecting portion 13. Wherein, the length of the first connecting rod portion 131 and the length of the second connecting rod portion 132 are smaller than the length of the supporting rod portion 14.

The central axis of the support rod portion 14 is parallel to the above-mentioned predetermined direction, and the length of the support rod portion 14 should be understood as the length of the support rod portion 14 in the predetermined direction.

In this way, after the stent 10 is compressed, the first connecting rod portion 131 and the second connecting rod portion 132 of the first mesh structure layer 11 do not interfere with the second mesh structure layer 12, so that the risk of abrasion of the stent 10 due to structural interference can be reduced, and the overall reliability of the stent 10 can be ensured.

Referring to fig. 6, fig. 6 is a schematic view showing an expanded structure of a third embodiment of the stent of the present invention.

In another exemplary embodiment, the stent 10 includes a first mesh layer 11 and a second mesh layer 12. The first mesh layer 11 and the second mesh layer 12 are disposed in this order in a direction from the blood flow outflow end B toward the blood flow inflow end a. The second mesh layer 12 in this embodiment is the target mesh layer described in the above embodiment. The first mesh layer 11 includes the above-described connection portion 13 and at least two support rod portions 14.

The support rod portion 14 is connected to the second mesh unit 32, and at this time, in order to avoid abrasion caused by interference between the connection portion 13 and the first mesh unit 31, the connection portion 13 protrudes in a direction away from the target mesh structure layer. In this way, even after the stent 10 is compressed, the connecting portion 13 does not interfere with the first mesh unit 31.

Referring to fig. 7, fig. 7 is a schematic view showing an expanded structure of a fourth embodiment of the stent of the present invention.

In another exemplary embodiment, the stent 10 includes a first mesh layer 11 and a second mesh layer 12. The first mesh layer 11 and the second mesh layer 12 are disposed in this order in a direction from the blood flow outflow end B toward the blood flow inflow end a.

The first mesh layer 11 in this embodiment is the target mesh layer described in the above embodiment. The second mesh layer 12 comprises a connection 13. Any two adjacent first mesh units 31 in the first mesh-like structure layer 11 are connected by a connection portion 13.

It should be noted that, in the case where the first end 311 of the first mesh unit is close to the blood flow inflow end a relative to the first end 321 of the second mesh unit and the second end 312 of the first mesh unit is close to the blood flow outflow end B relative to the second end 322 of the second mesh unit in this embodiment, the target mesh structure layer may be located at the blood flow inflow end a or the blood flow outflow end B, that is, the target mesh structure layer is close to the blood flow inflow end a or the blood flow outflow end B compared to other mesh structure layers of the stent 10, which is not limited herein.

In summary, the present invention provides a prosthetic valve device, wherein a first end of a first mesh unit and a first end of a second mesh unit are spaced apart from each other in a predetermined direction, and a second end of the first mesh unit and a second end of the second mesh unit are spaced apart from each other in the predetermined direction. Because the end parts of the first mesh unit and the second mesh unit are larger than the other positions of the first mesh unit and the second mesh unit after the stent is compressed, the ends of the first mesh unit and the second mesh unit are arranged to be spaced from each other in the preset direction, so that the ends of the first mesh unit and the second mesh unit are staggered from each other in the preset direction, the limit diameter size of the compressed artificial valve device is reduced, namely the artificial valve device can be compressed to a smaller diameter size, and the sheath inserting difficulty of the artificial valve device is reduced.

In addition, in the present invention, unless explicitly specified and limited otherwise, the terms "connected," "stacked," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and not for limiting the same; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the invention.

Claims

1. A prosthetic valve device, comprising:

the blood flow inlet end and the blood flow outlet end are oppositely arranged along a preset direction;

the support comprises a plurality of mesh structure layers distributed layer by layer along the preset direction, at least part of the mesh structure layers are target mesh structure layers, the target mesh structure layers comprise first mesh units and second mesh units, the first mesh units and the second mesh units are adjacent to each other in the preset circumferential direction, and the preset direction is perpendicular to a plane defined by the preset circumferential direction;

the first mesh unit and the second mesh unit each have a first end facing the blood flow inflow end and a second end facing the blood flow outflow end, the first end of the first mesh unit and the first end of the second mesh unit being spaced apart from each other in the preset direction, and the second end of the first mesh unit and the second end of the second mesh unit being spaced apart from each other in the preset direction;

a valve coupled to the stent.

2. The prosthetic valve device of claim 1,

the first end of the first mesh unit is adjacent to the blood flow inflow end relative to the first end of the second mesh unit, and the second end of the first mesh unit is adjacent to the blood flow inflow end relative to the second end of the second mesh unit.

3. The prosthetic valve device of claim 2,

a mesh layer adjacent to the target mesh layer connects the first end of the first mesh unit or the second end of the second mesh unit.

4. The prosthetic valve device of claim 3,

when a mesh layer adjacent to the target mesh layer is connected to a first end of the first mesh unit, the valve is connected to the stent through the first mesh unit;

and the valve is connected to the stent through the second mesh unit when a mesh layer adjacent to the target mesh layer is connected to the second end of the second mesh unit.

5. The prosthetic valve device of claim 1,

the first end of the first mesh unit is adjacent to the blood flow inflow end relative to the first end of the second mesh unit, and the second end of the first mesh unit is adjacent to the blood flow outflow end relative to the second end of the second mesh unit.

6. The prosthetic valve device of claim 5,

the mesh structure layer adjacent to the target mesh structure layer comprises a connecting part and at least two support rod parts, wherein the at least two support rod parts are sequentially distributed at intervals along the preset circumferential direction, and the connecting part is arranged between any two adjacent support rod parts;

the support rod part is connected with the first mesh unit, and the connecting part protrudes towards the target mesh structure layer.

7. The prosthetic valve device of claim 6,

the connecting part comprises a first connecting rod part and a second connecting rod part, the first connecting rod part is connected with the second connecting rod part, the first connecting rod part is also connected with the supporting rod part on one side of the connecting part, and the second connecting rod part is also connected with the supporting rod part on the other side of the connecting part;

the length of the first connecting rod part and the length of the second connecting rod part are smaller than the length of the supporting rod part.

8. The prosthetic valve device of claim 5,

the support rod portion is connected with the second mesh unit, and the connecting portion protrudes toward a direction away from the target mesh structure layer.

9. The prosthetic valve device of claim 5,

the mesh layer adjacent to the target mesh layer includes a connection portion;

any two adjacent first mesh units are connected through the connecting part.

10. The prosthetic valve device of any one of claims 1-9,

the reticular structure layer comprises at least two mesh units which are distributed along the preset circumferential direction in sequence;

the mesh unit density of the mesh structure layer near the blood flow outflow end is greater than the mesh unit density of the mesh structure layer near the blood flow inflow end.