CN116265912A - Detection device and detection method - Google Patents
Detection device and detection method Download PDFInfo
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- CN116265912A CN116265912A CN202111561694.2A CN202111561694A CN116265912A CN 116265912 A CN116265912 A CN 116265912A CN 202111561694 A CN202111561694 A CN 202111561694A CN 116265912 A CN116265912 A CN 116265912A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
Abstract
The invention discloses a detection device and a detection method, wherein the detection device comprises a light source mechanism, a collection mechanism and a receiving mechanism, the light source mechanism is used for emitting detection light to a flow channel of a flow chamber, the collection mechanism is used for collecting emergent light formed by the detection light after passing through the flow channel to form projection light, the receiving mechanism is used for receiving the projection light and forming light spots and projection of the flow channel, so that whether the relative positions of the light source mechanism and the flow chamber meet preset standards can be judged according to the projection of the light spots and the flow channel, the collection mechanism is arranged for collecting the detection light of the detection light after passing through the flow channel in the flow chamber and then outputting the detection light to the receiving mechanism, the projection precision of the light spots and the flow channel can be improved, the center alignment precision of the light source mechanism and the flow chamber can be improved, and the detection precision of a subsequent liquid sample can be improved.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a detection device and a detection method.
Background
The relative position of the flow cell and the light source mechanism in the blood analyzer for forming the sheath flow of the liquid sample directly affects the detection result of the liquid sample. For example, the light source mechanism needs to be aligned to the center position of the flow chamber, that is, the detection light emitted by the light source mechanism needs to be incident to the center position of the flow chamber, so that a good detection effect can be achieved.
At present, the light source mechanism and the flow chamber are generally only installed at preset positions, the installation accuracy of the light source mechanism cannot be guaranteed, whether the detection light emitted by the light source mechanism is aligned with the center position of the flow chamber cannot be accurately detected, and the subsequent sample detection result is directly affected.
Disclosure of Invention
The invention provides a detection device and a detection method, which are used for solving the technical problem that the relative position accuracy of projection of a light spot of detection light and a flow channel of a flow chamber is low by directly projecting the detection light on a light screen in the prior art.
In order to solve the technical problems, the invention provides a detection device, which comprises:
a light source mechanism for emitting detection light to the flow channel of the flow chamber;
the collecting mechanism is used for collecting emergent rays formed after the detection light passes through the flow channel so as to form projection rays;
and the receiving mechanism is used for receiving the projection light rays and forming the projection of the light spots and the flow channel, so that whether the relative positions of the light source mechanism and the flow chamber meet the preset standard can be judged according to the projection of the light spots and the flow channel.
In a specific embodiment, the detecting device further includes a processor, the receiving mechanism includes a photographing unit and a light screen, the light screen is used for receiving the projection light and forming the projection of the light spot and the flow channel, the photographing unit photographs the light screen received by the projection of the light spot and the flow channel to obtain a detection image, and the processor is used for judging whether the relative positions of the light source mechanism and the flow chamber meet a preset standard according to the detection image.
In a specific embodiment, the processor is configured to obtain, according to the detected image, a distance between a center line of the light spot along the extending direction of the flow channel and a center line of a projection of the flow channel along the extending direction of the flow channel, and determine whether the relative positions of the light source mechanism and the flow chamber meet a preset standard according to whether the distance is smaller than a minimum preset value.
In a specific embodiment, the processor is configured to obtain, according to the detection influence, a first detection value of a distance between a first side of the light spot and an inner wall of the flow channel, and a second detection value of a distance between a second side of the light spot opposite to the first side and the inner wall of the flow channel, and determine, according to whether a difference between the first detection value and the second detection value is smaller than a preset difference, whether a relative position between the light source mechanism and the flow chamber meets a preset standard.
In a specific embodiment, the processor is further configured to control the light source mechanism and/or the flow chamber to move according to the projection of the light spot and the flow channel, so that a center line of the light spot along the extending direction of the flow channel coincides with a center line of the projection of the flow channel along the extending direction of the flow channel.
In a specific embodiment, the collection mechanism comprises a first doublet or plano-convex lens.
In a specific embodiment, the detection device further includes a collimation mechanism, where the collimation mechanism is configured to receive the detection light and collimate the detection light so that the collimated detection light irradiates the flow channel of the flow chamber.
In a specific embodiment, the detection device further includes a shaping mechanism, where the shaping mechanism is configured to receive the collimated detection light and shape the detection light so that the shaped detection light irradiates the flow channel of the flow chamber.
In a specific embodiment, the shaping mechanism includes a lens and a second double-cemented lens, which are sequentially arranged, the lens is configured to diverge or converge the detection light in a first direction, the second double-cemented lens is configured to converge the detection light diverged or converged by the lens in a first direction and a second direction, and the first direction and the second direction are perpendicular.
In order to solve the technical problem, another technical scheme adopted by the invention is to provide a detection method, which comprises the following steps:
controlling the light source mechanism to emit detection light to the flow channel of the flow chamber;
the collecting mechanism is controlled to collect emergent rays formed after the detection light passes through the flow channel so as to form projection rays;
and controlling a receiving mechanism to receive the projection light and form a light spot and projection of the flow channel, so that whether the relative positions of the light source mechanism and the flow chamber meet the preset standard can be judged according to the light spot and the projection of the flow channel.
In a specific embodiment, the controlling the receiving mechanism to receive the projection light and form a light spot and a projection of the flow channel, so as to determine whether the relative positions of the light source mechanism and the flow chamber meet a preset standard according to the light spot and the projection of the flow channel includes:
controlling a light screen to receive the projection light and form projections of the light spots and the flow channels;
controlling a photographing unit to photograph the light screen which receives the light spot and the projection of the flow channel so as to obtain a detection image;
and the control processor judges whether the relative positions of the light source mechanism and the flow chamber meet the preset standard according to the detection image.
The detection device comprises a light source mechanism, a collection mechanism and a receiving mechanism, wherein the light source mechanism is used for emitting detection light to a flow channel of a flow chamber, the collection mechanism is used for collecting emergent light formed by the detection light after passing through the flow channel to form projection light, and the receiving mechanism is used for receiving the projection light and forming the projection of a light spot and the flow channel, so that whether the relative positions of the light source mechanism and the flow chamber meet the preset standard can be judged according to the projection of the light spot and the flow channel, the collection mechanism is arranged for collecting the detection light of the detection light after passing through the flow channel in the flow chamber and then outputting the detection light to the receiving mechanism, the projection precision of the light spot and the flow channel can be improved, the center alignment precision of the light source mechanism and the flow chamber can be improved, and the detection precision of a subsequent liquid sample can be improved.
Drawings
For a clearer description of the technical solutions of the embodiments of the present invention, the drawings that are needed in the description of the embodiments will be briefly introduced below, it being obvious that the drawings in the description below are only some embodiments of the present invention, and that other drawings can be obtained according to these drawings without inventive effort for a person skilled in the art, wherein:
FIG. 1 is a schematic perspective view of an embodiment of a detecting device according to the present invention;
FIG. 2 is a schematic view of an internal perspective structure of an embodiment of the detecting device of the present invention;
FIG. 3 is a schematic view of the internal cross-sectional structure of an embodiment of the detection device of the present invention;
FIG. 4 is a schematic diagram of a first lens assembly according to an embodiment of the present invention;
FIG. 5 is a schematic view of a projection of a light spot and a flow channel in an embodiment of the detection apparatus according to the present invention;
FIG. 6 is a schematic view of a projection of a light spot and a flow channel in an embodiment of a detection apparatus according to the present invention;
FIG. 7 is a schematic view of a projection of a light spot and a flow channel in an embodiment of a detection apparatus according to the present invention;
FIG. 8 is a schematic view of the internal cross-sectional structure of another embodiment of the detection device of the present invention;
FIG. 9 is a flow chart of an embodiment of the detection method of the present invention;
FIG. 10 is a flow chart of another embodiment of the detection method of the present invention.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present invention without making any inventive effort, are intended to fall within the scope of the present invention.
The terms "first," "second," and the like in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. In the description of the present application, the meaning of "plurality" means at least two, for example, two, three, etc., unless specifically defined otherwise. Furthermore, the terms "comprise" and "have," as well as any variations thereof, are intended to cover a non-exclusive inclusion. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those listed steps or elements but may include other steps or elements not listed or inherent to such process, method, article, or apparatus. And the term "and/or" is merely an association relation describing the association object, and indicates that three relations may exist, for example, a and/or B may indicate: a exists alone, A and B exist together, and B exists alone. In addition, the character "/" herein generally indicates that the front and rear associated objects are an "or" relationship.
Referring to fig. 1 to 4, the detection device 10 of the present invention includes a light source mechanism 100, a collecting mechanism 200, and a receiving mechanism, wherein the light source mechanism 100 is used for emitting detection light to a flow channel 201 of a flow chamber 20, the collecting mechanism 200 is used for collecting outgoing light formed by the detection light after passing through the flow channel 201 to form projection light, and the receiving mechanism is used for receiving the projection light and forming projections of a light spot 101 and the flow channel 201, so that whether the relative positions of the light source mechanism 100 and the flow chamber 20 meet preset standards can be judged according to the projections of the light spot 101 and the flow channel 201; by arranging the collecting mechanism 200 to collect the detection light passing through the flow channel 201 in the flow chamber 20 and then emit the detection light to the receiving mechanism, the projection accuracy of the light spot 101 and the flow channel 201 can be improved, the alignment accuracy of the light source mechanism 100 and the flow chamber 20 can be improved, and the detection accuracy of the subsequent liquid sample can be improved.
Specifically, when the flow cell 20 is applied to a sample analyzer, a liquid sample can form a liquid flow in the flow channel 201 of the flow cell 20, detection light emitted from the light source mechanism 100 to the flow channel 201 of the flow cell 20 can be scattered by the liquid flow to form scattered light, and the scattered light is detected by the detection mechanism in the sample analyzer, so that the detection of the liquid sample can be realized.
In the present embodiment, the light source mechanism 100 may be a point light source or the like, and is not limited thereto.
In the present embodiment, the light source mechanism 100 may be a monochromatic light source, such as red light, blue light, etc., and is not limited herein.
In this embodiment, the detection device 10 may further include a processor (not shown in the figure), the receiving mechanism includes a photographing unit (not shown in the figure) and a light screen 300, the light screen 300 is used for receiving the projection light and forming the projection of the light spot 101 and the flow channel 201, the photographing unit photographs the light screen 300 of the projection of the light spot 101 and the flow channel 201 to obtain a detection image, and the processor is used for judging whether the relative positions of the light source mechanism 100 and the flow chamber 20 meet the preset standard according to the detection image, and performing photographing through the photographing unit, and then performing judgment through a picture or a video, so that the accuracy of the judgment result can be improved.
In this embodiment, the receiving mechanism may further include an objective lens (not shown in the drawing), where the objective lens is disposed on the photographing unit and is located on a side of the photographing unit near the light screen 300, and the accuracy of the determination result can be further improved by amplifying the picture or video through the objective lens. In this embodiment, the magnification of the objective lens may be 10X or 20X, so that the detection light and the amplification of the flow channel 201 can be realized while the accuracy thereof is ensured, and interference between the objective lens 220 and the side wall of the flow chamber 20 is avoided.
In this embodiment, the detection device 10 may further include a driving mechanism (not shown in the figure), and the processor may be capable of driving the light source mechanism 100 and/or the flow chamber 20 to move by the driving mechanism.
In other embodiments, the light source mechanism 100 and/or the flow chamber 20 may also be manually moved by a person, without limitation.
In this embodiment, the processor may be an MCU (Microcontroller Unit, micro control unit) or the like. In this embodiment, the collecting mechanism 200 may include a first double-cemented lens 210, which can converge and reshape the outgoing light formed by the flow channel 201 in the flow chamber 20 to form the projection light, so that the projection light and the light spot 101 formed by the flow channel 201 on the light screen 300 and the projection accuracy of the flow channel 201 are higher, which is beneficial to improving the accuracy of the subsequent detection result of the liquid sample.
Referring to fig. 4 together, in this embodiment, the first double-cemented lens 210 may include a concave-convex lens 211 and a double-convex lens 212, where the convex surface of the concave-convex lens 211 is disposed towards the flow chamber 20, the concave surface of the concave-convex lens 211 is bonded with the first concave surface of the double-convex lens 212, and the second concave surface of the double-convex lens 212 is disposed away from the flow chamber 20, and the first double-cemented lens 210 formed by bonding the concave-convex lens 211 and the double-convex lens 212 is used for converging and shaping outgoing light, so that the effect of converging and shaping is better, and the accuracy of the subsequent detection result on the liquid sample is more beneficial to be improved.
In other embodiments, the collecting mechanism 200 may also include a plano-convex lens, where the plane of the plano-convex lens is disposed towards the flow chamber 20, and the convex surface is disposed opposite to the flow chamber 20, and the plano-convex lens is disposed to converge and reshape the outgoing light, so that the converging and reshaping effects are better, and the accuracy of the subsequent detection result on the liquid sample is more improved.
In this embodiment, white paper, white board, etc. may be further disposed on the light screen 300, which is beneficial to display of projection light.
In this embodiment, the detection device 10 may further include a housing 400, and the light source mechanism 100, the flow chamber 20, the collecting mechanism 200, and the receiving mechanism may be disposed in the housing 400, so that the housing 400 can play a role in protection and dust prevention.
In this embodiment, the processor is configured to determine whether the relative positions of the light source mechanism 100 and the flow chamber meet the preset standard according to the distance between the center line of the detected image acquisition light spot 101 along the extending direction of the flow channel 201 and the center line of the projection of the flow channel 201 along the extending direction of the flow channel 201, and according to whether the distance is smaller than the minimum preset value.
In this embodiment, the minimum preset value is greater than 0, and the maximum preset value is greater than the minimum preset value.
Specifically, referring to fig. 5, when a distance D0 between a center line L1 of the light spot 101 along the extending direction of the flow channel 201 and a center line L2 of the projection of the flow channel 201 of the flow chamber 20 along the extending direction of the flow channel 201 is greater than a maximum preset value D1, the center line L1 of the light spot 101 is far from the center line L2 of the projection of the flow channel 201, the light spot 101 does not cover the projection of the flow channel 201, and the relative positions of the light source mechanism 100 and the flow chamber 20 do not satisfy the preset standard; referring to fig. 6, when the distance D0 between the center line L1 of the spot 101 in the extending direction of the flow channel 201 and the center line L2 of the projection of the flow channel 201 in the extending direction of the flow channel 201 is smaller than or equal to the maximum preset value D1 and is greater than or equal to the minimum preset value D2, the center line L1 of the spot 101 is closer to the center line L2 of the projection of the flow channel 201 but still deviates, the projection of the spot 101 partially covers the flow channel 201 but still deviates from the projection of the flow channel 201, and the relative positions of the light source mechanism 100 and the flow chamber 20 do not satisfy the preset standard; referring to fig. 7, when the distance D0 between the center line L1 of the light spot 101 along the extending direction of the flow channel 201 and the center line L2 of the projection of the light spot 201 along the extending direction of the flow channel 201 is smaller than the minimum preset value D2 (the center line L1 of the light spot 101 along the extending direction of the flow channel 201 and the center line L2 of the projection of the light spot 101 along the extending direction of the flow channel 201 in the drawing coincide, that is, the distance between the center line L1 of the light spot 101 along the extending direction of the flow channel 201 and the center line L2 of the projection of the light spot 101 along the extending direction of the flow channel 201 is 0), the relative positions of the light source mechanism 100 and the flow chamber 20 satisfy the preset standard.
In other embodiments, the projection of the light spot 101 and the flow channel 201 formed on the light screen may be detected directly by manual visual inspection to determine whether the relative positions of the light source mechanism 100 and the flow cell 20 meet the preset criteria. For example, by manually measuring on a screener with a ruler, or identifying a fiducial line on a screener, etc.
In other embodiments, the processor may be further configured to obtain, according to the detected image, a first detection value of a distance between the first side of the light spot 101 and the inner wall of the flow channel 201, and a second detection value of a distance between the second side of the light spot 101 opposite to the first side and the inner wall of the flow channel 201, and determine whether the relative position of the light source mechanism 100 and the flow chamber 20 meets a preset criterion according to whether a difference between the first detection value and the second detection value is smaller than a preset difference.
Specifically, if the difference between the first detection value and the second detection value is greater than or equal to the preset difference, the light spot is deflected to one side of the inner wall of the flow channel 201, and the processor determines that the relative position of the light source mechanism 100 and the flow chamber 20 does not meet the preset standard; if the difference between the first detection value and the second detection value is smaller than the preset difference, the processor determines that the relative positions of the light source mechanism 100 and the flow chamber 20 meet the preset standard, if the difference indicates that the distance deviation between the light spot and the two opposite sides of the inner wall of the flow channel 201 is within the allowable range.
The processor is further configured to control the light source mechanism 100 and/or the flow chamber 20 to move according to the projection of the light spot 101 and the flow channel 201, so that the center line of the light spot 101 along the extending direction of the flow channel 201 coincides with the center line of the projection of the light spot 201 along the extending direction of the flow channel 201, and the adjustment process is simple and convenient to operate.
Referring to fig. 1, 2, 5 and 8, another embodiment of the detection device 10 of the present invention includes a light source mechanism 100, a collimation mechanism 500, a shaping mechanism 600, a collection mechanism 200 and a receiving mechanism 300, wherein the structures of the light source mechanism 100, the flow chamber 20, the collection mechanism 200 and the receiving mechanism are referred to the above embodiment of the detection device 10 and are not described herein again.
In this embodiment, the collimating mechanism 500 is configured to receive the detection light and collimate the detection light so that the collimated detection light irradiates the flow channel 201 of the flow chamber 20, and the collimating mechanism 500 may include an aspheric lens, where a plane of the aspheric lens faces the light source mechanism 100, and a curved surface of the aspheric lens faces away from the light source mechanism 100, so that the detection light can be incident from the plane of the aspheric lens and exit from the curved surface of the aspheric lens, so as to achieve a collimating effect on the detection light, which is beneficial to shaping and detecting light subsequently.
In this embodiment, the shaping mechanism 600 is configured to receive the collimated detection light and shape the detection light, so that the shaped detection light is irradiated to the flow channel 201 of the flow chamber 20, and the shaping mechanism 600 is configured to shape the detection light, which is beneficial to improving accuracy of subsequent detection results.
In this embodiment, the shaping mechanism 600 may include a lens 610 and a second double-cemented lens 620 that are sequentially set, and the second double-cemented lens 620 is configured to directly shape at least two directions, so that compared with a shaping mode that two directions are respectively implemented through two lenses, in this embodiment, the two lenses do not need to be accurately adjusted to implement shaping in two directions of the detection light, so that the assembly process of the shaping mechanism 600 can be simplified, the precision requirement and the cost of the shaping mechanism can be reduced, and the accuracy of the subsequent detection result can be improved.
In this embodiment, the lens 610 is configured to diverge or converge the detection light along a first direction, and the second double-cemented lens 620 is configured to converge the detection light diverged or converged by the lens 610 along a first direction and a second direction, where the first direction is perpendicular to the second direction, so as to implement shaping of the detection light along both directions, so as to facilitate subsequent detection, for example, detection of forward scattered light and/or side scattered light formed by the detection light through the flow chamber 20.
In this embodiment, the lens 610 may be a plano-concave cylindrical lens, the concave surface of the plano-concave cylindrical lens faces the collimating mechanism 500, and the plane of the plano-concave cylindrical lens faces away from the collimating mechanism 500, so that the detection light can be incident from the concave surface of the lens 610 and exit from the plane of the lens 610, so as to achieve divergence of the detection light.
In other embodiments, the lens 610 may also be a plano-convex cylindrical lens, where the plane of the plano-convex cylindrical lens faces the collimating mechanism 500, and the convex surface of the plano-convex cylindrical lens faces away from the collimating mechanism 500, so that the detection light can be incident from the plane of the lens 610 and exit from the convex surface of the lens 610 to achieve convergence of the detection light.
The second doublet 620 is similar to the first doublet 210 of the inspection apparatus 10 described above, and will not be described again.
Referring to fig. 1 to 5 and fig. 9, an embodiment of the detection method of the present invention includes:
s710, the light source mechanism 100 is controlled to emit detection light to the flow channel 201 of the flow cell 20.
In this embodiment, the light source mechanism 100 may be a laser light source, so as to facilitate detection of the liquid sample.
S720, controlling the collecting mechanism 200 to collect the emergent light formed by the detection light after passing through the flow channel 201 so as to form projection light.
S730, controlling the receiving mechanism to receive the projection light and form the projection of the light spot 101 and the flow channel 201 enables to determine whether the relative positions of the light source mechanism 100 and the flow chamber 20 meet the preset standard according to the projection of the light spot 101 and the flow channel 201.
In this embodiment, the projection of the light spot 101 of the projection light and the flow channel 201 of the flow chamber 20 can be detected by manual observation or comparison with the minimum preset value data to determine whether the light spot 101 of the projection light is located at the center of the flow channel 201 of the flow chamber 20.
In this embodiment, the collection mechanism 200 is configured to collect the detection light passing through the flow channel 201 in the flow chamber 20 and then output the collected detection light to the receiving mechanism, so that the projection accuracy of the light spot 101 and the flow channel 201 can be improved, the alignment accuracy of the light source mechanism 100 and the flow chamber 20 can be improved, and the detection accuracy of the subsequent liquid sample can be improved.
Referring to fig. 1 to 5 and 10, another embodiment of the detection method of the present invention includes:
s810, adjusting the relative positions of the light source mechanism 100 and the collimation mechanism 500.
In this embodiment, the relative positions of the light source mechanism 100 and the collimation mechanism 500 can be adjusted by a screw thread adjustment mode, so that the accuracy is high and the adjustment result is accurate.
S820, it is determined whether the mounting state of the flow chamber 20 on the mounting portion 202 for mounting the flow chamber 20 satisfies a preset criterion.
In this embodiment, the preset standard may be that the sidewall of the flow chamber 20 mounted on the mounting portion 202 is parallel to the vertical direction, wherein the vertical direction is defined as the front-rear direction in fig. 3.
S830, if the mounting state of the flow cell 20 on the mounting portion 202 for mounting the flow cell 20 meets the preset standard, the control mechanism controls the light source mechanism 100 to emit the detection light to the flow channel 201 of the flow cell 20.
S840, if the installation state of the flow chamber 20 on the installation portion 202 for installing the flow chamber 20 does not meet the preset standard, the installation of the flow chamber 20 is not qualified, and the installation state of the flow chamber 20 needs to be readjusted.
S850, controlling the collecting mechanism 200 to collect the emergent ray formed by the detection light after passing through the flow channel 201 in the flow chamber 20 to form projection ray.
S860, controlling the receiving mechanism to receive the projected light and form the projections of the light spot 101 and the flow channel 201 enables to determine whether the relative positions of the light source mechanism 100 and the flow chamber 20 meet the preset standard according to the projections of the light spot 101 and the flow channel 201.
In this embodiment, the method specifically includes:
s861, the control screen 300 receives the projection light and forms a projection of the light spot 101 and the flow channel 201.
S862, the photographing unit is controlled to photograph the projection screen 300 of the received light spot 101 and the flow channel 201 to obtain a detection image.
S863, the control processor judges whether the relative positions of the light source mechanism 100 and the flow chamber 20 meet the preset standard according to the detected image.
In this embodiment, the collection mechanism 200 is configured to collect the detection light passing through the flow channel 201 of the flow chamber 20 and then output the collected detection light to the receiving mechanism, so that the projection accuracy of the light spot 101 and the flow channel 201 can be improved, the alignment accuracy of the light source mechanism 100 and the flow chamber 20 can be improved, and the detection accuracy of the subsequent liquid sample can be improved.
The foregoing description is only of embodiments of the present invention, and is not intended to limit the scope of the invention, and all equivalent structures or equivalent processes using the descriptions and the drawings of the present invention or directly or indirectly applied to other related technical fields are included in the scope of the present invention.
Claims (11)
1. A detection apparatus, characterized by comprising:
a light source mechanism for emitting detection light to the flow channel of the flow chamber;
the collecting mechanism is used for collecting emergent rays formed after the detection light passes through the flow channel so as to form projection rays;
and the receiving mechanism is used for receiving the projection light rays and forming the projection of the light spots and the flow channel, so that whether the relative positions of the light source mechanism and the flow chamber meet the preset standard can be judged according to the projection of the light spots and the flow channel.
2. The apparatus according to claim 1, wherein the detecting apparatus further comprises a processor, the receiving means includes a photographing unit for receiving the projection light and forming projections of the light spot and the flow path, and a light screen for photographing the light screen received by the projection of the light spot and the flow path to obtain a detected image, and the processor is for judging whether or not the relative positions of the light source means and the flow chamber satisfy a preset criterion based on the detected image.
3. The apparatus according to claim 2, wherein the processor is configured to obtain, based on the detected image, a distance between a center line of the light spot along the extending direction of the flow channel and a center line of a projection of the flow channel along the extending direction of the flow channel, and determine whether the relative positions of the light source mechanism and the flow chamber satisfy a preset criterion according to whether the distance is smaller than a minimum preset value.
4. The detecting device according to claim 2, wherein the processor is configured to obtain, according to the detected image, a first detection value of a distance between a first side of the light spot and an inner wall of the flow channel, a second detection value of a distance between a second side of the light spot opposite to the first side and the inner wall of the flow channel, and determine whether the relative position of the light source mechanism and the flow chamber meets a preset criterion according to whether a difference between the first detection value and the second detection value is smaller than a preset difference.
5. The detection device according to claim 2, wherein the processor is further configured to control the light source mechanism and/or the flow cell to move such that a center line of the light spot along an extending direction of the flow channel coincides with a center line of the projection of the flow channel along the extending direction of the flow channel, based on the projections of the light spot and the flow channel.
6. The detection device of claim 1, wherein the collection mechanism comprises a first doublet or plano-convex lens.
7. The detection apparatus according to claim 1, further comprising a collimation mechanism for receiving the detection light and collimating the detection light so that the collimated detection light irradiates the flow channel of the flow cell.
8. The detection apparatus according to claim 7, further comprising a shaping mechanism for receiving the collimated detection light and shaping the detection light so that the shaped detection light irradiates the flow channel of the flow cell.
9. The apparatus according to claim 8, wherein the shaping mechanism includes a lens for diverging or converging the detection light in a first direction and a second double-cemented lens for converging the detection light diverged or converged by the lens in a first direction and a second direction, the first direction and the second direction being perpendicular.
10. A method of detection comprising:
controlling the light source mechanism to emit detection light to the flow channel of the flow chamber;
the collecting mechanism is controlled to collect emergent rays formed after the detection light passes through the flow channel so as to form projection rays;
and controlling a receiving mechanism to receive the projection light and form a light spot and projection of the flow channel, so that whether the relative positions of the light source mechanism and the flow chamber meet the preset standard can be judged according to the light spot and the projection of the flow channel.
11. The method according to claim 10, wherein the controlling the receiving means to receive the projected light and form a light spot and a projection of the flow channel to determine whether the relative positions of the light source means and the flow chamber satisfy a preset criterion based on the light spot and the projection of the flow channel comprises:
controlling a light screen to receive the projection light and form projections of the light spots and the flow channels;
controlling a photographing unit to photograph the light screen which receives the light spot and the projection of the flow channel so as to obtain a detection image;
and the control processor judges whether the relative positions of the light source mechanism and the flow chamber meet the preset standard according to the detection image.
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| CN202111561694.2A CN116265912A (en) | 2021-12-16 | 2021-12-16 | Detection device and detection method |
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| CN202111561694.2A CN116265912A (en) | 2021-12-16 | 2021-12-16 | Detection device and detection method |
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