CN116251509A

CN116251509A - Triaxial vortex vibration mixer

Info

Publication number: CN116251509A
Application number: CN202310100734.6A
Authority: CN
Inventors: 许雄飞; 杨智泽; 管华锋; 邵荣华; 王帆
Original assignee: Hangzhou Escola Biotechnology Co ltd
Current assignee: Hangzhou Escola Biotechnology Co ltd
Priority date: 2023-01-28
Filing date: 2023-01-28
Publication date: 2023-06-13

Abstract

A triaxial vortex vibration homogenizer comprising: a motor; an eccentric shaft; the transfer bracket is provided with a placing hole which is used for placing the sample test tube; the motor is in transmission connection with the eccentric shaft, the transmission support is connected with the eccentric shaft, the motor drives the transmission support to perform circular motion through the eccentric shaft, the motor drives the transmission support to vibrate through the eccentric shaft, collected samples are uniformly mixed, and meanwhile, the grating disc and the position sensor are arranged to achieve accurate positioning, so that results are conveniently collected, and accuracy of detection results is guaranteed.

Description

Triaxial vortex vibration mixer

Technical Field

The invention relates to the technical field of sample mixing, in particular to a triaxial vortex vibration mixer.

Background

In recent years, the newly developed isothermal amplification technology is an in vitro nucleic acid amplification technology, the reaction process is always kept at a constant temperature, and the purpose of rapid nucleic acid amplification is achieved by adding enzymes with different activities and specific primers. Isothermal amplification does not need the processes of thermal denaturation, temperature circulation, electrophoresis, ultraviolet observation and the like of a template, is simpler and more convenient than the conventional PCR technology, has the advantages of rapidness, specificity, simplicity, economy and the like, and has good application prospect in clinical and on-site rapid diagnosis.

However, many nucleic acid collection points do not have the capability of collecting a field detection sample, and can have the influence of transportation and aerosol, have the capability of collecting field detection and higher manufacturing cost, meanwhile, the mixing effect is poor, when the triaxial vortex vibration stops, the positioning is inaccurate, and when the optical head of a collection result scans the result, the position of the contrast is not the optimal position, so that the detection result has errors.

Disclosure of Invention

In view of the defects existing in the background art, the invention relates to a triaxial vortex vibration mixer, a motor drives a transmission bracket to vibrate through an eccentric shaft so as to mix collected samples, and meanwhile, a grating disk and a position sensor are arranged so as to realize accurate positioning, thereby facilitating the collection of results and ensuring the accuracy of detection results.

The invention relates to a triaxial vortex vibration mixer, comprising:

a motor;

an eccentric shaft;

the transfer bracket is provided with a placing hole which is used for placing the sample test tube;

the motor is in transmission connection with the eccentric shaft, the transmission support is connected with the eccentric shaft, and the motor drives the transmission support to move circularly through the eccentric shaft.

Through adopting above-mentioned scheme, constitute a motor and drive the structure of transmission support motion through the eccentric shaft, the mixing of the sampling pipe of conveniently placing.

Further, the device also comprises a grating disk and a position sensor, wherein the grating disk and the position sensor are arranged between the eccentric shaft and the motor and are used for positioning the transmission bracket.

By adopting the scheme, the zero position can be positioned, the transmission support is conveniently stopped at the same position every time, and the optical head can conveniently acquire the result.

Further, the eccentric shaft comprises a main eccentric shaft and a secondary eccentric shaft, the main eccentric shaft is in transmission connection with the motor, and the main eccentric shaft and the secondary eccentric shaft are both connected with the transmission bracket.

By adopting the scheme, the stability during uniform mixing is ensured.

Further, the connecting lugs are arranged on two sides of the placing hole of the transfer support, one connecting lug of one side is connected with the main eccentric shaft, and the connecting lug of the other side is connected with the auxiliary eccentric shaft.

Through adopting above-mentioned scheme, the setting and the installation of convenient transmission support.

Further, the device also comprises a balancing weight, wherein the balancing weight is used for balancing the rotational inertia.

By adopting the scheme, the rotary inertia is balanced, the noise is reduced, and the stability is improved.

Further, the device also comprises a reference plate, wherein the reference plate is provided with a through hole for the eccentric shaft to pass through, and the eccentric shaft is connected with the transmission bracket after passing through the through hole.

By adopting the scheme, the whole installation is convenient.

Further, the motor is a servo motor.

By adopting the scheme, the accuracy in stopping is improved.

Further, the motor is characterized by further comprising a first support plate and a second support plate, wherein the first support plate is connected with the reference plate through an upright post, the second support plate is connected with the first support plate through the upright post, the first support plate is used for installing a grating disc, a balancing weight, a main eccentric shaft and a position sensor, and the second support plate is used for installing a motor.

By adopting the scheme, the installation of the grating disk, the balancing weight, the main eccentric shaft and the motor is facilitated.

Drawings

Fig. 1 is a schematic structural view of embodiment 1 of the present invention.

Reference numerals: 1. a motor; 21. a main eccentric shaft; 22. a slave eccentric shaft; 3. a transfer bracket; 31. placing the hole; 4. a grating disk; 5. a position sensor; 6. balancing weight; 7. a reference plate; 8. a first support plate; 9. a second support plate; 10. and (5) a column.

Description of the embodiments

The following description and the discussion of the embodiments of the present invention will be made more complete and less in view of the accompanying drawings, in which it is to be understood that the invention is not limited to the embodiments of the invention disclosed and that it is intended to cover all such modifications as fall within the scope of the invention.

For the purpose of facilitating an understanding of the embodiments of the present invention, reference will now be made to the drawings, by way of example, of specific embodiments, and the various embodiments should not be construed to limit the embodiments of the invention.

The embodiment 1 of the invention relates to a triaxial vortex vibration mixer, which comprises a motor 1, an eccentric shaft and a transmission support 3, wherein the transmission support 3 is provided with a placement hole 31, the placement hole 31 is used for placing a sample test tube, a heating and temperature controlling device is arranged at the placement hole 31 and is used for heating the sample test tube and keeping the temperature stable, the motor 1 is in transmission connection with the eccentric shaft, the transmission support 3 is connected with the eccentric shaft, and the motor 1 drives the transmission support 3 to move circularly through the eccentric shaft.

The working principle of the embodiment is as follows:

placing the sample test tube into the placing hole 31, starting the motor 1, driving the transmission support 3 to perform circular motion by the motor 1 through the eccentric shaft to complete uniform mixing, and detecting results by using an optical head arranged at the lower part of the transmission support 3 after uniform mixing to complete detection.

In embodiment 2 of the present invention, on the basis of embodiment 1, a triaxial vortex vibration mixer is further provided with a grating disk 4 and a position sensor 5, wherein the grating disk 4 and the position sensor 5 are disposed between an eccentric shaft and the motor 1 and are used for positioning the transmission bracket 3, and since the vortex vibration mixing step is a circular motion, when the motion stops, an error exists in the position of the transmission bracket 3, and when the optical head detects, the detection position is not the optimal position, and the grating disk 4 and the position sensor 5 are disposed, so that the zero point position can be positioned, and the vortex vibration can be effectively controlled to stop at the same position after the vortex vibration stops.

In embodiment 3 of the present invention, based on embodiment 1, the motor 1 is replaced by a servo motor, and after the servo motor is selected, the grating disk 4 and the position sensor 5 may not be provided, so that the production is more convenient, and meanwhile, the stop at the zero position after each operation is ensured, so that the scanning is convenient.

In embodiment 4 of the present invention, on the basis of embodiment 2 or embodiment 3, the eccentric shaft includes a main eccentric shaft 21 and a secondary eccentric shaft 22, the main eccentric shaft 21 is in transmission connection with the motor 1, the main eccentric shaft 21 and the secondary eccentric shaft 22 are both connected with the transmission bracket 3, and the main eccentric shaft 21 and the secondary eccentric shaft 22 are disposed in the same plane to ensure stability during rotation.

The two sides of the transmission support 3, which are positioned on the placement holes 31, are provided with connecting lugs, wherein one connecting lug on one side is connected with the main eccentric shaft 21, the connecting lug on the other side is connected with the auxiliary eccentric shaft 22, the two sides of the transmission support 3 are provided with connecting lugs which facilitate the connection of the transmission support 3 and the eccentric shaft, two auxiliary eccentric shafts 22 are arranged, and the transmission support 3 is provided with connecting lugs which are in quantity corresponding to the auxiliary eccentric shaft 22.

One of the main eccentric shafts 21 and the two auxiliary eccentric shafts 22 keep the horizontal transmission support 3, and the upper and lower swinging in the process of vibration and uniform mixing can not influence the uniform mixing effect.

In embodiment 5 of the present invention, on the basis of embodiment 4, a triaxial vortex vibration mixer further includes a balancing weight 6, the balancing weight 6 is used for balancing rotational inertia, the balancing weight 6 is disposed at the main eccentric shaft 21, and since the center of the rotation track of the transmission bracket 3 is not coincident with the rotation center of the motor 1, eccentricity is generated, there is a problem of unbalanced rotational inertia, and the balancing weight 6 is disposed for balancing rotational inertia, so as to avoid the problems of large noise and unstable vortex vibration.

In the embodiment 6 of the invention, on the basis of the embodiment 5, the triaxial vortex vibration mixer further comprises a reference plate, a first support plate 8 and a second support plate 9, wherein the eccentric shaft penetrates through the reference plate to be connected with the transmission support 3, the transmission is directly attached to the reference plate, the horizontal state during vortex vibration is guaranteed, the first support plate 8 is connected with the reference plate through a stand column 10, the second support plate 9 is connected with the first support plate 8 through the stand column 10, the first support plate 8 is used for installing the grating disk 4, the balancing weight 6, the main eccentric shaft 21 and the position sensor 5, the second support plate 9 is used for installing the motor 1, and the first support plate 8 and the second support plate 9 are convenient for installing the grating disk 4, the balancing weight 6, the main eccentric shaft 21 and the motor 1.

Meanwhile, the invention can set up the multi-group vortex mixing structure, wherein set up 3 groups as the best, can design the size easy to produce, mount, carry, put, meanwhile, the effective improvement detects the efficiency, wherein the multi-group vortex mixing structure is set up along the identity straight line, use the identity straight line to set up the optical head that can be set up and can move, namely the optical head is set up and can drive the optical head to reciprocate along the straight line to drive the structure, set up so can save the setting up of the optical head, can gather the sample tube that the multi-group transmits 3 put through an optical head, through the movement scanning of the optical head at the same time, combine the scanning result, produce the linear image, can take the value according to the linear image, compared with the optical head of the traditional fixed point scanning detection, this structure can further reduce the error when the optical head gathers the result.

Finally, it should be noted that: the above examples are only specific embodiments of the present invention, and are not intended to limit the scope of the present invention, but it should be understood by those skilled in the art that the present invention is not limited thereto, and that the present invention is described in detail with reference to the foregoing examples: any person skilled in the art may modify or easily conceive of the technical solution described in the foregoing embodiments, or perform equivalent substitution of some of the technical features, while remaining within the technical scope of the present disclosure; such modifications, changes or substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention, and are intended to be included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims

1. A triaxial vortex vibration mixer, characterized by comprising:

an electric motor (1);

an eccentric shaft;

the transfer bracket (3), the transfer bracket (3) is provided with a placing hole (31), and the placing hole (31) is used for placing a sample test tube;

the motor (1) is in transmission connection with the eccentric shaft, the transmission support (3) is connected with the eccentric shaft, and the motor (1) drives the transmission support (3) to move circularly through the eccentric shaft.

2. The triaxial vortex vibration homogenizer of claim 1, wherein: the device also comprises a grating disk (4) and a position sensor (5), wherein the grating disk (4) and the position sensor (5) are arranged between the eccentric shaft and the motor (1) and used for positioning the transmission bracket (3).

3. The triaxial vortex vibration homogenizer of claim 1, wherein: the motor (1) is a servo motor.

4. A triaxial vortex vibration mixer according to claim 2 or 3, characterised in that: the eccentric shaft comprises a main eccentric shaft (21) and a secondary eccentric shaft (22), the main eccentric shaft (21) is in transmission connection with the motor (1), and the main eccentric shaft (21) and the secondary eccentric shaft (22) are both connected with the transmission bracket (3).

5. The triaxial vortex vibration homogenizer of claim 4, wherein: the transmission support (3) is provided with connecting lugs at two sides of the placement hole (31), wherein the connecting lug at one side is connected with the main eccentric shaft (21), and the connecting lug at the other side is connected with the auxiliary eccentric shaft (22).

6. The triaxial vortex vibration homogenizer of claim 5, wherein: the balance weight (6) is used for balancing the moment of inertia.

7. The triaxial vortex vibration homogenizer of claim 6, wherein: the eccentric shaft is connected with the transmission bracket (3) after passing through the through hole.

8. The triaxial vortex vibration homogenizer of claim 2, wherein: the motor is characterized by further comprising a first support plate (8) and a second support plate (9), wherein the first support plate (8) is connected with the reference plate through a stand column (10), the second support plate (9) is connected with the first support plate (8) through the stand column (10), and the second support plate (9) is used for installing the motor (1).