CN116251302A - Photodynamic therapeutic instrument probe for treating cervical cancer front lesion and photodynamic therapeutic instrument - Google Patents

Photodynamic therapeutic instrument probe for treating cervical cancer front lesion and photodynamic therapeutic instrument Download PDF

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CN116251302A
CN116251302A CN202310232902.7A CN202310232902A CN116251302A CN 116251302 A CN116251302 A CN 116251302A CN 202310232902 A CN202310232902 A CN 202310232902A CN 116251302 A CN116251302 A CN 116251302A
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probe
cervical
ring
pole
treatment
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苗彩霞
严冬
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Qingdao Leishi Optoelectronics Technology Co ltd
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Qingdao Leishi Optoelectronics Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/303Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the vagina, i.e. vaginoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • A61N5/0603Apparatus for use inside the body for treatment of body cavities
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • A61N5/0603Apparatus for use inside the body for treatment of body cavities
    • A61N2005/0611Vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/065Light sources therefor
    • A61N2005/0651Diodes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

The utility model relates to a cervical cancer treatment's field especially relates to a photodynamic therapy appearance of pathological change before treatment cervical cancer, and the photodynamic therapy appearance probe of pathological change before the treatment cervical cancer, including the probe body and be located the inside luminous body of probe body, the probe body of probe body for the printing opacity material is made, the probe body is including being used for putting into the intraductal first probe pole of cervical and rigid coupling are in the second probe pole of first probe pole one end, works as first probe pole is located when the intraductal, the second probe pole orientation the one end of first probe pole and the external orifice butt of cervical. The application has the effects of reducing the frequency of probe replacement and shortening the treatment time.

Description

Photodynamic therapeutic instrument probe for treating cervical cancer front lesion and photodynamic therapeutic instrument
Technical Field
The application relates to the field of cervical cancer treatment, in particular to a photodynamic therapeutic apparatus for treating cervical cancer pre-lesions.
Background
Photodynamic therapy (PDT) is a novel method for treating tumors, precancerous lesions, proliferative skin diseases and vascular diseases by using photosensitizing drugs and laser activation. The irradiation of the focus part with specific wavelength can activate the photosensitive medicine selectively gathered in the focus tissue to trigger photochemical reaction to destroy focus. The photosensitizing drugs in the new generation of photodynamic therapy (PDT) transfer energy to surrounding oxygen, generating singlet oxygen with very high activity. The singlet oxygen can perform oxidation reaction with the nearby biomacromolecule to generate cytotoxin so as to kill the lesion cells. PDT has the advantage over conventional therapies that it enables accurate and effective treatment with minimal side effects.
Currently photodynamic therapy is an emerging field of tumor treatment, and in gynaecological indications are: high risk HPV infection, cervical intraepithelial neoplasia, cervical cancer (unable to operate or recur after operation), vaginal cancer, vulvar cancer, etc. The advantages are that the method is minimally invasive and even noninvasive, can eliminate hidden focus, selectively kill tumor cells, does not destroy normal tissues, can keep the structural integrity of female genital organs, and does not affect normal fertility requirements. Because of no obvious systemic adverse reaction, the medicine is particularly suitable for patients with poor general conditions and no tolerance to other treatment methods, and can repeatedly treat for many times. The medicine is applied locally, and has little side effect on the whole body.
At present, when cervical cancer is treated, a probe is usually selected to irradiate the cervical canal to treat a lesion part in the cervical canal; then another probe is replaced, so that the other probe irradiates the cervical external orifice to treat the lesion part at the cervical external orifice. The probe needs to be replaced reciprocally, the operation is very troublesome, and the treatment time is long.
Disclosure of Invention
In order to reduce the frequency of probe replacement and shorten the treatment time, the application provides a photodynamic therapeutic apparatus for treating cervical cancer pre-lesions.
The application provides a photodynamic therapy instrument for treating cervical cancer pre-lesions adopts the following technical scheme:
in a first aspect, the present application provides a photodynamic therapeutic apparatus probe for treating cervical cancer pre-lesions, which adopts the following technical scheme:
the utility model provides a photodynamic therapy appearance probe of pathological change before treatment cervical cancer, includes the probe body and is located the inside luminous body of probe body, the probe body that the probe body was made for the printing opacity material, the probe body is including being used for putting into the intraductal first probe pole of cervical and rigid coupling are in the second probe pole of first probe pole one end, works as first probe pole is located when the intraductal, the second probe pole orientation the one end of first probe pole and cervical outer mouth butt.
By adopting the technical scheme, before use, the photosensitizer is injected into a patient in a coating or injection mode, so that the photosensitizer is positioned at a focus position. When the cervical canal is used, the first probe rod is directly placed in the cervical canal, and at the moment, one end of the second probe rod, which faces the first probe rod, is abutted against the cervical external opening. When the light emitted by the light emitter irradiates the photosensitizer at the focus position, the photosensitizer generates singlet oxygen and other active oxygen components, so that the tumor cells at the focus position are photodamaged. The light emitted by the luminous bodies in the first probe rod and the second probe rod can irradiate the cervical canal and the external cervical orifice at the same time, so that the probe does not need to be replaced. The treatment of multiple parts can be realized through one probe, and the treatment is carried out on the multiple parts simultaneously, so that the frequency of probe replacement is greatly reduced, and the treatment time is shortened.
Optionally, the diameter of the second probe rod is larger than that of the first probe rod, and the second probe rod is used for being abutted with the inner wall of the vagina.
Through adopting above-mentioned technical scheme, when cervical cancer pathological changes appear, cancer cells all can appear near the cervical canal, if cancer cells spread in the vagina, the photosensitizer that is located the human body also will enrich in the cancer cells department in the vagina, because the second probe pole is the printing opacity material, so when the luminous body of second probe pole inside shines on the photosensitizer, also will make the photosensitizer in the vagina take place the chemical reaction and destroy the cancer cells in the vagina, the treatment is more comprehensive.
Optionally, the probe body further includes an abutment ring fixedly connected to the outer wall of the second probe rod, the abutment ring is located at one end of the second probe rod, which is close to the first probe rod, and the outer ring of the abutment ring can be abutted to the cervical fornix.
Through adopting above-mentioned technical scheme, when carrying out the treatment to the patient, discover that many patient's treatment is not thorough, cancer cells relapse, research discovers that there are cancer cells also all over in cervical vault department, and because the fold of cervical vault department is more, light is difficult to shine to cervical vault department, so the cancer cells of this department can't eliminate to cause patient's postoperative relapse. The arrangement of the abutting ring enables the abutting ring to be abutted against the cervical fornix when the probe of the photodynamic therapeutic apparatus stretches into the therapeutic part, and light emitted by the luminous body inside the abutting ring can directly irradiate the cervical fornix through the abutting ring, so that cancer cells at the cervical fornix are cleared.
Optionally, the abutment ring extends gradually from a side close to the second probe rod to a side far away from the second probe rod towards the direction in which the first probe rod is located.
By adopting the technical scheme, the abutting ring is more suitable for the shape of the cervical fornix of the human body.
Optionally, the inner part of the abutting ring is divided into a plurality of areas, and the luminous body in each area is controlled by the same switch.
By adopting the technical scheme, the luminous bodies in the corresponding areas can be started in different diseased areas, targeted treatment is realized, and the treatment is more flexible.
Optionally, the luminous bodies comprise a first luminous body installed in the first probe rod, a second luminous body installed in the second probe rod and a third luminous body installed in the abutting ring;
the first illuminant is dispersion optical fiber or liquid silica gel;
the second illuminant and the third illuminant are one of dispersion optical fiber, LED lamp and liquid silica gel.
By adopting the technical scheme, the luminous body can emit light, and the probe of the photodynamic therapeutic instrument can be provided with light.
Optionally, a control member for controlling the abutting ring to open or controlling the abutting ring to shrink is arranged in the abutting ring.
Through adopting above-mentioned technical scheme, can control the butt ring through the control and open or laminate with first probe pole for when stretching into human focus with this photodynamic therapy appearance probe, can shrink through the control butt ring, be convenient for the work of putting into of photodynamic therapy appearance probe. After the probe of the photodynamic therapeutic apparatus is placed in the focus position, the abutting ring is controlled to be opened by the control piece, so that the abutting ring abuts against the cervical fornix, and the operation is more convenient and flexible.
Optionally, the butt ring is inside hollow structure, the control is including being located inside gas tube and the gas tube of second probe pole, gas tube with the equal one end of gas tube with inside intercommunication in the butt ring, the other end is followed the second probe pole is kept away from the one end of first probe pole exposes to the external world.
Through adopting above-mentioned technical scheme, when needs stretch into human focus with photodynamic therapy appearance probe, can be through the bleed pipe with the inside gassing of butt ring, the butt ring will lose the support this moment and be convenient for pass the butt ring from the vaginal orifice. When the abutting ring is positioned at the focus position, the inside of the abutting ring is inflated through the inflation tube, so that the abutting ring is restored under the action of gas, and is abutted to the cervical fornix, and the operation is very convenient.
Optionally, the butt ring has memory attribute, the butt ring is kept away from one side of second probe pole is provided with the turn-ups, the control is including installing stay cord in the turn-ups, stay cord both ends follow the butt ring with after the inside passthrough of second probe pole, follow the second probe pole is kept away from one end of first probe pole exposes to the external world.
Through adopting above-mentioned technical scheme, under the normal condition, under butt ring self memory effect, the butt ring is in open condition, when needs operation butt ring and first probe pole laminating, and the doctor directly pulls the stay cord in outside, and the stay cord can drive butt ring outer lane shrink to suitable butt ring laminating is on first probe pole, realizes the control to the butt ring open end.
In a second aspect, the present application provides a photodynamic therapeutic apparatus, which adopts the following technical scheme:
a photodynamic therapeutic apparatus comprises the photodynamic therapeutic apparatus probe for treating cervical cancer and a camera installed at one end of the second probe rod far away from the first probe rod.
Through adopting above-mentioned technical scheme, the camera can provide the illumination for the installation of probe body, the installation of the probe body of being convenient for more.
In summary, the present application includes at least one of the following beneficial technical effects:
1. according to the cervical canal and cervical external orifice treatment device, the first probe rod and the second probe rod are arranged, and the probe body made of light-transmitting materials is selected, so that after the probe body is placed at a cervical lesion part, the luminous bodies in the probe body can provide light for the cervical canal and the cervical external orifice simultaneously, so that photosensitizer at the cervical canal and the cervical external orifice is excited to eliminate cancer cells, the cervical canal and the cervical external orifice can be treated simultaneously through one probe, and the treatment efficiency is higher;
2. the abutting ring is arranged, so that cancer cells at the cervical fornix can be eliminated, the treatment is more thorough, and the treatment effect is better;
3. the second probe rod diameter is greater than the setting of first probe rod diameter for the second probe rod can laminate with the vagina inner wall, realizes the treatment to the cancer cell of vagina department, through a probe body, can treat the cancer cell of cervical canal, cervical external orifice, cervical fornix and vagina department simultaneously, and treatment effect is better, and treatment efficiency is higher.
Drawings
Fig. 1 is a schematic diagram of the overall structure of a probe of a photodynamic therapy device according to the present application.
Fig. 2 is a schematic view in front elevation cut-away of fig. 1.
Fig. 3 is an enlarged schematic view at a in fig. 2.
Fig. 4 is a schematic diagram of another form of a control member.
Fig. 5 is a schematic diagram of the overall structure of the photodynamic therapy device according to the present application.
Reference numerals illustrate: 1. a probe body; 11. a first probe rod; 12. a second probe rod; 13. an abutment ring; 2. a light emitting body; 21. a first light-emitting body; 22. a second illuminant; 23. a third illuminant; 24. dispersing the optical fiber; 25. an LED lamp; 26. a connector; 3. a control member; 31. flanging; 32. a pull rope; 33. an inflation tube; 34. a gas release pipe; 4. a camera is provided.
Detailed Description
The present application is described in further detail below in conjunction with figures 1-5.
The embodiment of the application discloses a photodynamic therapeutic instrument probe for treating cervical cancer pre-lesions. Referring to fig. 1 and 2, a probe of a photodynamic therapy device for treating a precancerous lesion of cervical cancer includes a probe body 1 and a luminous body 2 installed inside the probe body 1. The probe body 1 is made of a flexible material with certain hardness, has light transmittance, and specifically, the material of the probe body 1 can be made of medical transparent silica gel, polytetrafluoroethylene resin or other materials capable of meeting requirements. The probe body 1 made of flexible materials is convenient to put into a focus part of a patient, and hard damage to the patient is avoided; the probe body 1 is placed more smoothly due to certain hardness; the light emitted by the illuminant 2 can directly penetrate the probe body 1 to irradiate the focus part of a patient, thereby eliminating cancer cells.
Referring to fig. 1 and 2, the probe body 1 includes a first probe rod 11 and a second probe rod 12 integrally fixedly connected to one end of the first probe rod 11, the first probe rod 11 and the second probe rod 12 are internally communicated, and the diameter of the second probe rod 12 is greater than that of the first probe rod 11. When the first probe rod 11 is stretched into the cervical canal in use, one end of the second probe rod 12 facing the first probe rod 11 is abutted against the external cervical orifice, and the outer wall of the second probe rod 12 is abutted against the inner vaginal wall. It will be appreciated that prior to treatment, the photosensitizer is injected into the patient in a coated or injectable manner and will automatically become enriched on cancer cells. After the probe body 1 is placed at the focus part, the luminous body 2 is started, the light emitted by the luminous body 2 penetrates through the first probe rod 11 and the second probe rod 12, wherein the light emitted by the luminous body 2 in the first probe rod 11 irradiates the cervical canal, so that the photosensitizer is subjected to chemical reaction to eliminate cancer cells in the cervical canal; the light emitted from the light emitter 2 located in the second probe rod 12 also irradiates the external cervical orifice from the end of the second probe rod 12 facing the first probe rod 11, and eliminates cancer cells at the external cervical orifice. Because the second probe rod 12 is also made of transparent materials, the second probe rod 12 is abutted against the inner wall of the vagina, when cancer cells spread into the vagina, the photosensitizer is also enriched on the cancer cells in the vagina, so that the photosensitizer at the vagina is chemically reacted by the light emitted by the illuminant 2 in the second probe rod 12 to eliminate the cancer cells in the vagina. The cancer cells at the cervical canal, the cervical external orifice and the vagina can be eliminated simultaneously through one probe body 1, the probe is not required to be replaced circularly, and the treatment efficiency is higher.
When doctors treat patients, the disease of some patients is repeatedly found, so that the treatment is not thorough. Through researches, cancer cells of some patients can spread to the cervical fornix, and as the cervical fornix of the human body has more folds, the illumination is difficult to reach the deep part of the cervical fornix during treatment, so that the cancer cells at the cervical fornix of the human body are difficult to eliminate, and the disease is repeatedly caused.
In order to eliminate cancer cells at the cervical fornix of the human body, the treatment effect is perfected. Referring to fig. 1 and 2, the probe body 1 further includes an abutment ring 13 fixedly connected to a side wall of the second probe rod 12, the abutment ring 13 is located at one end of the second probe rod 12 facing the first probe rod 11, and the outer wall of the first probe rod 11 is in smooth transition with the abutment ring 13. When the probe body 1 is placed in the lesion, the abutment ring 13 is also embedded in the cervical dome. When the illuminant 2 in the probe body 1 is turned on, the light emitted by the illuminant 2 irradiates the cervical fornix through the abutting ring 13, so that the elimination of cancer cells at the cervical fornix is realized.
The outer ring of the abutting ring 13 is bent towards the direction of the first probe rod 11, so that the abutting ring 13 is bowl-shaped as a whole, and the opening of the abutting ring 13 faces towards the direction of the first probe rod 11. The shape of the abutting ring 13 is consistent with that of the cervical fornix of the human body, when the abutting ring 13 is placed in the cervical fornix of the human body, the abutting ring 13 can prop open folds of the cervical fornix, so that the abutting ring 13 is more attached to the cervical fornix, and the treatment effect is better.
Referring to fig. 2 and 3, in order to facilitate manipulation of the abutment ring 13 through the vagina to the cervical fornix, a control member 3 is provided on the abutment ring 13 to control the opening of the abutment ring 13 or the contraction of the abutment ring 13. When the abutting ring 13 is required to be placed in the cervical fornix, the abutting ring 13 can be controlled by the control piece 3 to be attached to the first probe rod 11, so that the abutting ring 13 can be conveniently penetrated through the vagina to reach the cervical fornix; when the abutting ring 13 reaches the cervical fornix, the abutting ring 13 can be controlled to be unfolded through the control piece 3, so that the abutting ring 13 restores the bowl-shaped structure to unfolded the folds at the cervical fornix, and cancer cells at the cervical fornix can be eliminated.
Referring to fig. 2 and 3, in one example of the present application, the abutment ring 13 has a memory property, and the abutment ring 13 is bowl-shaped in its own memory state. And be provided with turn-ups 31 at the butt ring 13 outer lane, turn-ups 31 are buckled to the direction that butt ring 13 inner wall is located, have placed stay cord 32 in turn-ups 31, and stay cord 32 middle part is located turn-ups 31, and the both ends of stay cord 32 wear out from turn-ups 31 to pass from the inside of butt ring 13 and the inside of second probe pole 12, finally stretch out the external world from the one end that second probe pole 12 kept away from first probe pole 11. Normally, the abutting ring 13 is bowl-shaped under the action of the self memory attribute of the abutting ring 13. When the abutting ring 13 is required to be placed in the cervical fornix, a doctor can pull the end part of the stay cord 32 extending out of the second probe rod 12, so that the stay cord 32 positioned in the flange 31 is driven to be reduced, the open end of the abutting ring 13 is contracted, and the abutting ring 13 can be very conveniently penetrated from the vagina at the moment. Until the abutment ring 13 is positioned at the cervical dome, at which point the force exerted on the pull cord 32 is released and the abutment ring 13 recovers under its own memory properties.
Referring to fig. 4, in another example of the present application, the abutment ring 13 is made of soft transparent material, such as transparent silica gel. The abutting ring 13 is of a hollow structure with a hollow inside, and the inside of the abutting ring 13 is not communicated with the inside of the second probe rod 12. The control member 3 comprises an air charging pipe 33 and an air discharging pipe 34 which are positioned in the second probe rod 12, wherein the uniform ends of the air charging pipe 33 and the air discharging pipe 34 are communicated to the inside of the abutting ring 13, and the other end of the air charging pipe extends to the outside from one end of the second probe rod 12 far away from the first probe rod 11. It will be appreciated that valves for controlling the on-off of the air inflation tube 33 and the air deflation tube 34 are installed at the ends of the air inflation tube 33 and the air deflation tube 34 located outside, and the ends of the air inflation tube 33 located outside are connected with external inert gas (such as nitrogen). When it is necessary to place the abutment ring 13 in the cervical fornix, the gas in the abutment ring 13 can be discharged through the gas discharge pipe 34, and at this time, the abutment ring 13 loses support and contracts, so that the vagina can pass smoothly to reach the cervical fornix. When the abutting ring 13 reaches the cervical fornix, the external inert gas is conveyed into the abutting ring 13 through the gas filled tube 33, so that the abutting ring 13 can be spread, and the abutting ring 13 is attached to the cervical fornix.
Referring to fig. 2, the luminous body 2 is simultaneously installed inside the first probe rod 11, the second probe rod 12 and the abutment ring 13 to emit bright light to irradiate on the photosensitizer of cancer cells, so that the photosensitizer chemically reacts to eliminate the cancer cells.
The luminous body 2 comprises a first luminous body 21 mounted in the first probe rod 11, a second luminous body 22 mounted in the second probe rod 12 and a third luminous body 23 mounted in the abutment ring 13.
The diameter of the cervical canal of the human body is smaller, so that the diameter of the first probe rod 11 is also smaller, and is 3mm, and therefore, the first illuminant 21 can be selected from the dispersive optical fiber 24 and liquid silica gel. One end of the first illuminant 21 is located in the first probe rod 11, the other end is used for being connected with an external light source, the external light source can select laser or an LED lamp, and the light of an external power source can be transmitted to the inside of the probe body 1 through the first illuminant 21, so that light emission is realized.
The second illuminant 22 can be a dispersion optical fiber 24, an LED lamp 25 or liquid silica gel, and when the second illuminant 22 is a dispersion optical fiber 24 or liquid silica gel, one end of the second illuminant 22 is located in the second probe rod 12, and the other end is connected with an external light source, and the external light source can also be a laser or an LED, etc., so as to realize the luminescence of the second illuminant 22. When the second illuminant 22 selects the LED lamp 25, the other end of the LED lamp 25 is connected with an external power supply, and when the LED lamp 25 is powered on, light emission can be realized.
The third illuminant 23 is consistent with the second illuminant 22, and one of the dispersion optical fiber 24, the LED lamp 25 and the liquid silica gel can be selected, and will not be described in detail here.
It can be understood that the illuminant 2 located in the probe body 1 can be fixed on the inner wall of the probe body 1 by a buckle, and can be fixed on the inner wall of the probe body 1 by other modes, so long as the illuminant 2 can be fixed, the specific installation mode can be selected according to the need, and the detailed description is omitted.
Referring to fig. 2, a connector 26 is mounted at an end of the second probe rod 12 remote from the first probe rod 11, and the luminous body 2 is connected to the connector 26. When in use, the connector 26 is connected with an external light source or an external power supply, so that the luminous body 2 can be controlled to emit light. The control piece 3 passes through the connector 26, so that the control piece 3 can control the abutting ring 13 to shrink or stretch.
Here, the inside of the abutment ring 13 may be divided into a plurality of regions, and the present application describes an example in which the inside of the abutment ring 13 is divided into four regions. The luminous bodies 2 in each area are controlled by the same switch, so that when the novel multifunctional luminous device is used, the luminous bodies 2 in the corresponding areas can be controlled to emit light by the corresponding switches according to the focus position of a patient, and the operation is more flexible.
The implementation principle of the photodynamic therapeutic instrument probe for treating cervical cancer pre-lesions is as follows: before use, the photosensitizer is injected into a patient by coating or injection, and the photosensitizer is enriched on cancer cells. When in use, the abutting ring 13 can be controlled to shrink by the control piece 3, and then the probe body 1 is placed in a focus part, so that the first probe rod 11 stretches into the cervical canal, and the second probe rod 12 is abutted against the external cervical orifice towards one end of the first probe rod 11. The abutment ring 13 is then controlled by the control member 3 to reposition such that the abutment ring 13 abuts against the cervical dome, thereby spreading the folds at the cervical dome open. The illuminant 2 is operated to emit light, and the light emitted by the illuminant 2 passes through the probe body 1 to reach the cancer cell, so as to excite the photosensitizer at the cancer cell to generate chemical reaction, and eliminate the cancer cell. Can eliminate cancer cells at cervical canal, cervical external orifice, vagina and cervical fornix simultaneously, does not need to replace probes, greatly reduces the time of replacing probes, shortens the treatment time and improves the treatment effect.
The embodiment of the application also discloses a photodynamic therapeutic apparatus for treating cervical cancer pre-lesions. Referring to fig. 5, the photodynamic therapy device for treating cervical cancer pre-lesion comprises the above-mentioned photodynamic therapy device probe for treating cervical cancer pre-lesion and a camera 4 mounted on the probe body 1, wherein the camera 4 is mounted at one end of the first probe rod 11 far away from the second probe rod 12, and the camera 4 can be connected with an external display screen. So that in use, the barrel camera 4 can take a picture of the scene at the front end of the first probe rod 11. The doctor can observe the picture shot by the camera 4 at the display screen and operate the first probe rod 11 to move according to the picture, so that the first probe rod 11 can be smoothly placed into the cervical canal.
The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.

Claims (10)

1. A photodynamic therapeutic instrument probe for treating cervical cancer pre-lesions, which is characterized in that: including probe body (1) and be located inside luminous body (2) of probe body (1), probe body (1) are probe body (1) that printing opacity material was made, probe body (1) are including being used for imbedding first probe pole (11) and the rigid coupling in the cervical canal second probe pole (12) of first probe pole (11) one end, work as first probe pole (11) are located when the cervical canal, second probe pole (12) orientation the one end and the external cervical mouth butt of first probe pole (11).
2. The photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 1, wherein: the diameter of the second probe rod (12) is larger than that of the first probe rod (11), and the second probe rod (12) is used for being abutted with the inner wall of the vagina.
3. The photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 1, wherein: the probe body (1) further comprises an abutting ring (13) fixedly connected to the outer wall of the second probe rod (12), the abutting ring (13) is located at one end, close to the first probe rod (11), of the second probe rod (12), and the outer ring of the abutting ring (13) can be abutted to the cervical fornix.
4. A photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 3, wherein: the abutting ring (13) gradually extends from one side close to the second probe rod (12) to one side far away from the second probe rod (12) to the direction where the first probe rod (11) is located.
5. A photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 3, wherein: the abutting ring (13) is internally divided into a plurality of areas, and the luminous bodies (2) in each area are controlled by the same switch.
6. The photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 2, wherein: the luminous body (2) comprises a first luminous body (21) installed in the first probe rod (11), a second luminous body (22) installed in the second probe rod (12) and a third luminous body (23) installed in the abutting ring (13);
the first illuminant (21) is a dispersion optical fiber (24) or liquid silica gel;
the second luminous body (22) and the third luminous body (23) are one of a dispersion optical fiber (24), an LED lamp (25) and liquid silica gel.
7. The photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 2, wherein: a control piece (3) for controlling the abutting ring (13) to open or controlling the abutting ring (13) to shrink is arranged in the abutting ring (13).
8. The photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 7, wherein: the butt ring (13) is of a hollow structure with a hollow inside, the control piece (3) comprises an inflation tube (33) and a deflation tube (34) which are positioned inside the second probe rod (12), one end of each inflation tube (33) and one end of each deflation tube (34) are communicated with the inside of the butt ring (13), and the other end of each inflation tube is exposed to the outside from one end, away from the first probe rod (11), of the second probe rod (12).
9. The photodynamic therapy device probe for the treatment of pre-cervical cancer lesions according to claim 7, wherein: the butt ring (13) has memory property, one side that butt ring (13) kept away from second probe pole (12) is provided with turn-ups (31), control piece (3) are including installing stay cord (32) in turn-ups (31), stay cord (32) both ends follow butt ring (13) with after second probe pole (12) are inside to pass, follow second probe pole (12) are kept away from one end of first probe pole (11) exposes to the external world.
10. A photodynamic therapy device, characterized in that: a photodynamic therapy device probe comprising a device as claimed in any one of claims 1 to 9 for the treatment of pre-cervical lesions and a camera (4) mounted at an end of the second probe rod (12) remote from the first probe rod (11).
CN202310232902.7A 2023-03-11 2023-03-11 Photodynamic therapeutic instrument probe for treating cervical cancer front lesion and photodynamic therapeutic instrument Pending CN116251302A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310232902.7A CN116251302A (en) 2023-03-11 2023-03-11 Photodynamic therapeutic instrument probe for treating cervical cancer front lesion and photodynamic therapeutic instrument

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202310232902.7A CN116251302A (en) 2023-03-11 2023-03-11 Photodynamic therapeutic instrument probe for treating cervical cancer front lesion and photodynamic therapeutic instrument

Publications (1)

Publication Number Publication Date
CN116251302A true CN116251302A (en) 2023-06-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202310232902.7A Pending CN116251302A (en) 2023-03-11 2023-03-11 Photodynamic therapeutic instrument probe for treating cervical cancer front lesion and photodynamic therapeutic instrument

Country Status (1)

Country Link
CN (1) CN116251302A (en)

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