CN116227233B - Method, device and equipment for estimating deployment length of non-uniform stent in blood vessel - Google Patents

Method, device and equipment for estimating deployment length of non-uniform stent in blood vessel Download PDF

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CN116227233B
CN116227233B CN202310483816.3A CN202310483816A CN116227233B CN 116227233 B CN116227233 B CN 116227233B CN 202310483816 A CN202310483816 A CN 202310483816A CN 116227233 B CN116227233 B CN 116227233B
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单晔杰
向建平
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Arteryflow Technology Co ltd
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Abstract

The application relates to a method, a device and equipment for estimating the unfolding length of a non-uniform stent in a blood vessel, which are characterized in that a three-dimensional blood vessel model is constructed, the blood vessel center line and corresponding center point parameters are extracted, the model of the non-uniform stent to be implanted is obtained, the stent parameters are extracted correspondingly, the axial mesh numbers of different stent sections of the non-uniform stent are calculated, the stent is discretely expressed into a plurality of coaxial short cylinders which are arranged along the blood vessel center line, after the far-end position of the stent unfolded in the blood vessel is obtained, the unfolding length of each short cylinder is calculated according to the stent section parameters corresponding to each short cylinder and the center point data, in the calculation process, the processing number of the short cylinders is accumulated, and when the accumulated number is equal to the axial mesh number of the corresponding stent section, the lower stent section parameters are adopted for calculation when the next short cylinder processing is carried out. The method can accurately predict the unfolding length of the non-uniform stent in the blood vessel.

Description

Method, device and equipment for estimating deployment length of non-uniform stent in blood vessel
Technical Field
The application relates to the technical field of conversion medicine, in particular to a method, a device and equipment for estimating the expansion length of a non-uniform stent in a blood vessel.
Background
Intracranial aneurysms refer to abnormal bulging of the intracranial arterial wall, with an overall prevalence of about 3% -5%. At present, the intervention treatment mode for small and medium-sized aneurysms, especially ruptured aneurysms mainly utilizes a metal spring ring to plug the aneurysm cavity, so that the impact of blood flow on the tumor wall is slowed down, the thrombosis in the aneurysm cavity is initiated, and finally the effect of sealing the aneurysm cavity is achieved. For large aneurysms or spindle aneurysms of wide carotid aneurysms, the dense mesh braided stent can achieve better treatment effect.
After the dense mesh braided stent is implanted into a blood vessel, the metal coverage rate of the dense mesh braided stent at the position of the neck of the aneurysm plays a key role in the occlusion of the aneurysm. In contrast, in the non-tumor neck location, higher metal coverage would present a risk of occluding healthy branches. For this reason, some manufacturers have developed non-uniform dense mesh woven stents to reduce the risk of side branch occlusion while ensuring tumor lumen occlusion.
Because of the significant foreshortening properties of dense mesh stents, the length of the stent after implantation into a vessel is inherently difficult to predict accurately. Non-uniform stents introduce non-uniformity in the foreshortening behavior, making stent length prediction more difficult.
Disclosure of Invention
In view of the foregoing, it is desirable to provide a method, apparatus, and device for estimating the deployment length of a non-uniform stent in a blood vessel, which can accurately estimate the deployment length of a non-uniform braided stent after implantation in the blood vessel.
A method of estimating a deployment length of a non-uniform stent in a vessel, the method comprising:
acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
obtaining the model of a non-uniform stent implanted into a blood vessel, and extracting relevant stent parameters from a stent database according to the model;
the non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of the mesh in the support parameters;
dispersing the non-uniform stent into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, wherein the central point of each virtual cylinder coincides with the central line of the blood vessel;
Acquiring the distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the stretching length of the virtual cylinder corresponding to the current central point;
determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the bracket parameters corresponding to the next bracket section when calculating the stretching length of the next virtual cylinder when the number of the virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of the virtual cylinders subjected to accumulation processing;
and until all the virtual cylinders are processed, the sum of the stretching lengths of the virtual cylinders is the estimated length of the non-uniform stent stretching in the blood vessel.
In one embodiment, the calculating the stretching length of the virtual cylinder corresponding to the current center point according to the center point data corresponding to the distal end position on the blood vessel center line and the corresponding stent segment parameters includes:
calculating by adopting a stretching radius model according to the center point data and the parameters of the corresponding support segments to obtain the stretching radius of the virtual cylinder corresponding to the current center point;
And calculating by adopting a bracket shortening model according to the stretching radius of the virtual cylinder to obtain the stretching length of the virtual cylinder.
In one embodiment, the extended radius model is expressed as:
Figure SMS_1
in the above-mentioned description of the invention,
Figure SMS_4
representing the current center point, +.>
Figure SMS_6
Representing the center point +.>
Figure SMS_8
Corresponding three-dimensional vessel radius->
Figure SMS_3
Representing the center point +.>
Figure SMS_5
The stretching radius of the corresponding virtual cylinder, < ->
Figure SMS_7
Representing the upper limit of the expanded diameter of the implanted stent in the naturally released state, wherein said +.>
Figure SMS_9
From the data of the centre point,said->
Figure SMS_2
Obtained from the parameters of the corresponding stent segments.
In one embodiment, the stent foreshortening model represents:
Figure SMS_10
,/>
Figure SMS_11
in the above formula, the
Figure SMS_12
For the number of stent filaments, said +.>
Figure SMS_15
Is the side length of the bracket diamond lattice, which is +.>
Figure SMS_17
For the diameter of the stent, said +.>
Figure SMS_14
Is the diameter of the stent wire, wherein the +.>
Figure SMS_16
And->
Figure SMS_18
Derived from the stent parameters, said +.>
Figure SMS_19
Calculated from the stretching radius of the virtual cylinder, said +.>
Figure SMS_13
And calculating according to the bracket parameters.
In one embodiment, the method for estimating the deployment length of the non-uniform stent in the blood vessel further includes calculating the length of the non-uniform stent after densification in the blood vessel, including:
After the distal end position of the non-uniform stent in the three-dimensional blood vessel model is obtained, calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the pushing length of the virtual cylinder corresponding to the current central point;
determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained compaction length, sequentially calculating the compaction length of each virtual cylinder, adopting the support parameter corresponding to the next support section when calculating the stretching length of the next virtual cylinder when the number of virtual cylinders subjected to accumulation processing is equal to the mesh number of the current support section, and re-accumulating the number of virtual cylinders subjected to accumulation processing;
and until all the virtual cylinders are processed, the sum of the pushing lengths of the virtual cylinders is the estimated expanding length of the non-uniform stent after being pushed in the blood vessel.
In one embodiment, the calculating according to the center point data and the corresponding bracket segment parameters corresponding to the distal end position on the blood vessel center line to obtain the pushing length of the virtual cylinder corresponding to the current center point includes:
calculating according to the center point data and the parameters of the corresponding support segments to obtain the stretching length of the virtual cylinder corresponding to the current center point;
Calculating according to the parameters of the corresponding stent sections to obtain the expansion diameter pushing upper limit of the stent sections in an unconstrained state;
respectively extracting the equivalent diameter of the three-dimensional blood vessel cross section area and the equivalent diameter of the three-dimensional blood vessel cross section perimeter corresponding to the current center point according to the data of the corresponding center point;
processing according to the expansion diameter pushing upper limit, the three-dimensional blood vessel cross-section area equivalent diameter and the three-dimensional blood vessel cross-section perimeter equivalent diameter to respectively obtain the pushing radius upper limit of the current virtual short cylinder based on the area ratio definition adherence and the perimeter ratio definition adherence;
calculating by using a secret radius model according to the secret radius upper limit and the stretching length to obtain the secret length of the corresponding virtual cylinder;
and calculating by adopting a bracket shortening model according to the pushing length of the virtual cylinder to obtain the pushing length of the virtual cylinder.
In one embodiment, the radius of the push model is expressed as:
Figure SMS_20
wherein:
Figure SMS_21
or (b)
Figure SMS_22
Figure SMS_23
In the above-mentioned description of the invention,
Figure SMS_25
representing the current center point, +.>
Figure SMS_28
Represents the upper limit of the push radius,/, for>
Figure SMS_30
Indicating the length of stretch->
Figure SMS_24
Representing the equivalent diameter of the three-dimensional blood vessel cross-section area corresponding to the current center point,/->
Figure SMS_27
Represents the equivalent diameter of the perimeter of the three-dimensional blood vessel section corresponding to the current center point,/- >
Figure SMS_29
Representation pushDensity (Tight)>
Figure SMS_31
And->
Figure SMS_26
Is constant.
A non-uniform stent deployment length estimation device in a vessel, the device comprising:
the central point data acquisition module is used for acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, extracting a blood vessel central line of a target area in the three-dimensional blood vessel model, and extracting central point data corresponding to each central point on the blood vessel central line;
the appointed stent parameter extraction module is used for obtaining the model of the non-uniform stent implanted into the blood vessel and extracting related stent parameters from a stent database according to the model;
the support sections correspond to mesh number calculation modules and are used for the non-uniform support, wherein the non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of a grid according to the support parameters;
the bracket discrete module is used for dispersing the non-uniform bracket into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, and the central point of each virtual cylinder coincides with the central line of the blood vessel;
The first calculation module of the stretching length of the virtual cylinder is used for obtaining the far-end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the far-end position on the blood vessel central line and the parameters of the corresponding stent segments to obtain the stretching length of the virtual cylinder corresponding to the current central point;
the second calculation module of the stretching length of the virtual cylinder is used for determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the corresponding bracket parameter of the next bracket section when calculating the stretching length of the next virtual cylinder when the number of virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of virtual cylinders subjected to processing;
and the stent expansion estimated length obtaining module is used for processing all the virtual cylinders until the virtual cylinders are processed, and the sum of the expansion lengths of the virtual cylinders is the expansion estimated length of the non-uniform stent in the blood vessel.
A computer device comprising a memory storing a computer program and a processor which when executing the computer program performs the steps of:
Acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
obtaining the model of a non-uniform stent implanted into a blood vessel, and extracting relevant stent parameters from a stent database according to the model;
the non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of the mesh in the support parameters;
dispersing the non-uniform stent into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, wherein the central point of each virtual cylinder coincides with the central line of the blood vessel;
acquiring the distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the stretching length of the virtual cylinder corresponding to the current central point;
determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the bracket parameters corresponding to the next bracket section when calculating the stretching length of the next virtual cylinder when the number of the virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of the virtual cylinders subjected to accumulation processing;
And until all the virtual cylinders are processed, the sum of the stretching lengths of the virtual cylinders is the estimated length of the non-uniform stent stretching in the blood vessel.
A computer readable storage medium having stored thereon a computer program which when executed by a processor performs the steps of:
acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
obtaining the model of a non-uniform stent implanted into a blood vessel, and extracting relevant stent parameters from a stent database according to the model;
the non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of the mesh in the support parameters;
dispersing the non-uniform stent into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, wherein the central point of each virtual cylinder coincides with the central line of the blood vessel;
Acquiring the distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the stretching length of the virtual cylinder corresponding to the current central point;
determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the bracket parameters corresponding to the next bracket section when calculating the stretching length of the next virtual cylinder when the number of the virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of the virtual cylinders subjected to accumulation processing;
and until all the virtual cylinders are processed, the sum of the stretching lengths of the virtual cylinders is the estimated length of the non-uniform stent stretching in the blood vessel.
According to the method, the device and the equipment for estimating the unfolding length of the non-uniform stent in the blood vessel, the three-dimensional blood vessel model is constructed, the blood vessel center line and the corresponding center point parameters are extracted, the model of the non-uniform stent to be implanted is obtained, the stent parameters are extracted correspondingly, the axial mesh numbers of different stent sections corresponding to the non-uniform stent are calculated, the stent is discretely expressed into a plurality of coaxial short cylinders which are arranged along the blood vessel center line, after the far-end position of the stent unfolded in the blood vessel is obtained, the unfolding length of each short cylinder is calculated according to the stent section parameters corresponding to each short cylinder and the center point data, in the calculation process, the processing numbers of the short cylinders are accumulated, and when the accumulated amount is equal to the axial mesh number of the corresponding stent section, the parameters of the lower stent section are adopted for calculation when the next short cylinder processing is carried out. The method can accurately predict the unfolding length of the non-uniform stent in the blood vessel.
Drawings
FIG. 1 is a flow chart of a method for estimating the deployment length of a non-uniform stent in a vessel in one embodiment;
FIG. 2 is a schematic illustration of the geometry of a non-uniformly woven stent in one embodiment;
FIG. 3 is a simplified schematic diagram of a geometry of a non-uniformly woven stent in one embodiment;
FIG. 4 is a block diagram of a device for estimating the deployment length of a non-uniform stent in a blood vessel in one embodiment;
fig. 5 is an internal structural diagram of a computer device in one embodiment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application will be further described in detail with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the present application.
Aiming at the problems that a dense net stent has obvious shortness, the length of the dense net stent after being implanted into a blood vessel is difficult to be accurate, and the non-uniform stent has non-uniformity of shortness, so that the length prediction of the stent becomes more difficult, as shown in fig. 1, the method for estimating the unfolding length of the non-uniform stent in the blood vessel is provided, and comprises the following steps:
step S100, acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
Step S110, obtaining the model of the non-uniform stent implanted into the blood vessel, and extracting relevant stent parameters from a stent database according to the model;
step S120, calculating the axial nominal length of each bracket section and the axial diagonal nominal length of the grid according to bracket parameters to obtain the mesh number of each bracket section in the axial direction, wherein the non-uniform bracket comprises a first bracket section, a second bracket section and a third bracket section which are arranged along the axis;
step S130, dispersing the non-uniform stent into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, wherein the central point of each virtual cylinder coincides with the central line of the blood vessel;
step S140, obtaining the distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the distal end position on the blood vessel central line and the parameters of the corresponding stent segments to obtain the stretching length of the virtual round short cylinder corresponding to the current central point;
step S150, determining the center point position of the next virtual cylinder on the blood vessel center line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the bracket parameter corresponding to the next bracket section when calculating the stretching length of the next virtual cylinder when the number of the virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of the virtual cylinders subjected to accumulation processing;
Step S160, until all the virtual cylinders are processed, the sum of the stretching lengths of the virtual cylinders is the estimated length of the non-uniform stent stretching in the blood vessel.
It should be noted that the stents appearing in this application are all woven stents.
The geometry of the non-uniformly woven stent is first decomposed in the axial direction. As shown in fig. 2, the geometry of the non-uniformly woven stent may be divided into 5 sections, a middle working section, two end anchoring sections, and a transition section between the working and anchoring sections (within the dashed box of fig. 1). The 5 segments of the stent are labeled as a first segment, a second segment, a third segment, a fourth segment, and a fifth segment, respectively. Respectively of length of
Figure SMS_32
、/>
Figure SMS_33
、/>
Figure SMS_34
、/>
Figure SMS_35
And->
Figure SMS_36
In general, the manufacturing process determines that the working segment of the non-uniform dense mesh braided stent is continuously transited to the anchoring segment, with no clear boundary between the transition segment and the anchoring segment. The manufacturer will not normally explicitly calibrate the length of the transition section and therefore can simply set the length of the transition section to 0. In this case, the simplified geometry of the non-uniformly woven stent is shown in FIG. 3.
It is easy to think that if the manufacturer calibrates the length of the transition section and even gives the distribution function of the mesh size of the transition section accurately, the technology can still realize accurate simulation of the bracket through further subdivision of the transition section. Thus, while the following is illustrative of the simplified geometry of a non-uniformly woven stent, the non-simplified geometry of a non-uniformly woven stent is still within the scope of the present invention. Further, it is also conceivable that when the lengths of the first segment and the second segment are both equal to 0, the non-uniformly braided stent is degraded to a uniformly braided stent. Therefore, the method is a general and wide technology, and the virtual implantation method of the uniform stent is also within the protection scope of the invention.
In step S100, a three-dimensional vessel model is constructed from medical image data including, but not limited to, three-dimensional image sequences of DSA (digital subtraction angiography), CTA (CT angiography) and MRA (magnetic resonance angiography). When the three-dimensional blood vessel model is constructed, software with the function of reconstructing the three-dimensional blood vessel model can be adopted to reconstruct the three-dimensional blood vessel, and meanwhile, a threshold method, a level set method or an artificial intelligent segmentation model (such as 3D UNet) can be utilized to segment the image sequence, and then a marching cube algorithm is used to reconstruct the surface of the image sequence, so that the three-dimensional blood vessel model is obtained.
Furthermore, the region of interest in the three-dimensional vascular model, namely the target region, is extracted, and the aneurysm-carrying arterial portion are reserved when the extraction is performed. The extraction operation may be performed using software having a region extraction function. The general target area is a fixed location range after stent implantation into a vessel.
Further, when extracting a vessel centerline in a three-dimensional vessel model in a target region, a voronoi diagram from a vessel proximal opening to a distal opening is calculated. From each voronoi diagram, a sequence of coordinates of all points on the centerline from the proximal opening to the end of each distal opening and a corresponding sequence of along-line radii (maximum inscribed sphere radii) are obtained.
Then, center point data including a tangent unit vector, a principal normal vector, and a secondary normal vector at each point of the center line are calculated from the coordinates of each point on the center line, and a radius of curvature, a blood vessel cross-sectional area, and a blood vessel cross-sectional surface perimeter at each point of the center line are calculated. The center point data are all calculated before the subsequent calculation, and in the subsequent calculation, the center point data are directly applied, so that the efficiency is improved.
In step S110, after the designated implantation stent model is acquired, a nominal stent length, a stent wire length, and a wire length corresponding to the stent model are acquired in a stent database.
In this embodiment, the stent database is pre-constructed, and only direct extraction is required when the stent database is needed in the method. The nominal diameter, the wire diameter, the number of wires, the length of wire segments and the nominal braiding angle of the stent corresponding to all stent types are included in the stent database. Where the nominal diameter of the stent refers to the diameter of the stent that the manufacturer provides on the stent package. The nominal diameter and the number of stent wires are provided by the stent manufacturer, and the length of the stent wire segments can be obtained by measurement or by a mathematical formula.
In step S120, as can be seen from the above description, the non-uniform stent includes three stent sections sequentially connected, namely, a first stent section, a second stent section and a third stent section, wherein mesh parameters of the first stent section and the third stent section are consistent and different from those of the second stent section.
By describing the tubule geometry of the braided stent as a diamond-shaped representative mesh, the foreshortening behavior of the braided stent is also determined by the geometry of the representative mesh. Each representative mesh comprises an axial diagonal length
Figure SMS_37
Circumferential diagonal Length->
Figure SMS_38
Side length->
Figure SMS_39
Braiding angle->
Figure SMS_40
. The number of stent wires remains unchanged due to the different stent segments, thus being segmented differently
Figure SMS_41
Remain unchanged, other parameters are respectivelyDifferent, as shown in fig. 3. The mesh count for each stent segment of a non-uniform stent can be determined using the following equation, which refers to the mesh count along the stent axial direction:
Figure SMS_42
,/>
Figure SMS_43
(1)
in formula (1), subscript i denotes a different stent segment,
Figure SMS_44
representing the nominal length of the corresponding carrier section, +.>
Figure SMS_45
Showing the nominal length of the axial diagonal of the mesh of the corresponding stent section, wherein +>
Figure SMS_46
And +.>
Figure SMS_47
Are stent parameters.
In step S130, when calculating the expansion length of the stent after being implanted into the blood vessel, the three-dimensional blood vessel model is used to calculate the expansion length, at this time, the stent may be discretized into a plurality of virtual cylinders sequentially arranged along the blood vessel center line, the center point of each virtual cylinder coincides with the blood vessel center line, each cylinder is actually a circle of mesh on the circumferential wall of the stent, and the axial length of each cylinder is the axial diagonal length of the mesh. Since the diameters of the blood vessels are different from each other after the stent is implanted in the blood vessels, the diameters of the stents implanted in the blood vessels are also changed correspondingly. Correspondingly, the length of each cylinder is also changed, and the changed length is the stretching length of each cylinder.
Step S140 and step S150 are both processes of solving the stretching length of each cylinder, and because the stent is a non-uniform stent, in the method, the stent parameters and the center point data corresponding to each stent segment are used to calculate respectively, wherein the number of processed cylinders is accumulated, and when the accumulated number is the total number of meshes of the current stent segment, the next stent segment parameter is used to calculate the stretching length of the next cylinder.
Specifically, after the specified distal end position is obtained, calculating the center point data corresponding to the position and the bracket parameters of the first bracket section or the third bracket section to obtain the unfolding length of the first cylinder, determining the center line point position of the next cylinder according to the length, and repeating the steps until all cylinders are processed.
In this embodiment, calculating the stretching length of the virtual cylinder corresponding to the current center point according to the center point data corresponding to the distal end position on the blood vessel center line and the corresponding stent segment parameters includes: and calculating by adopting a stretching radius model according to the central point data and the corresponding support segment parameters to obtain the stretching radius of the virtual cylinder corresponding to the current central point, and calculating by adopting a support shortening model according to the stretching radius of the virtual cylinder to obtain the stretching length of the virtual cylinder.
Wherein the extended radius model is expressed as:
Figure SMS_48
(2)
in the formula (2) of the present invention,
Figure SMS_50
representing the current center point, +.>
Figure SMS_53
Represents the center point +.>
Figure SMS_55
Corresponding three-dimensional vessel radius->
Figure SMS_49
Represents the center point +.>
Figure SMS_52
The stretching radius of the corresponding virtual cylinder, < ->
Figure SMS_54
Represents the upper limit of the deployment diameter of the implanted stent in the natural release state, wherein +.>
Figure SMS_56
Derived from centre point data->
Figure SMS_51
Obtained from the parameters of the corresponding stent segments.
Wherein, the stent shortening model represents:
Figure SMS_57
(3)
in the formula (3) of the present invention,
Figure SMS_59
for the number of stent filaments>
Figure SMS_62
Is the side length of the diamond lattice of the bracket +.>
Figure SMS_64
For the diameter of the stent>
Figure SMS_58
Is the diameter of the stent wire, wherein +.>
Figure SMS_61
And->
Figure SMS_63
Derived from stent parameters, +.>
Figure SMS_65
Calculated according to the stretching radius of the virtual cylinder,
Figure SMS_60
and calculating according to the bracket parameters.
Specifically, the stent foreshortening model is used to describe the axial length versus diameter of the mesh in each stent segment. Under the assumption that the stent is always circular in cross section after being released in a blood vessel and the side length of the stent mesh
Figure SMS_66
Equation (3) is obtained under the assumption that the overlap position of the stent wire is always unchanged (i.e., only relative rotation can occur and relative sliding cannot occur).
Specifically, when calculating the stretching length of each round short cylinder, determining the distal anchor point of the stent on the target central line, obtaining the id of the distal anchor point on the central line, and selecting the nominal diameter and the nominal length of the stent. According to the id of the far end point P on the central line, the three-dimensional coordinate, the radius along the line and other parameters along the line of the far end point P are obtained, and the stretching radius is calculated according to a formula (2) under the natural release state (without additional pushing operation) of the stent.
Without loss of generality, it is assumed that the first stent segment is a distal stent anchoring segment. Calculation of the expanded Length of the first mesh Using the shortening model
Figure SMS_67
And searching for a new point P_new to the near end of the central line according to the length, wherein the distance from P_new to P along the line is equal to +.>
Figure SMS_68
. Then the three-dimensional coordinates of the P_new position, the radius along the line and other parameters along the line are obtained, P_new is set as P, the steps are repeated, and the meshes are counted until the number of the meshes is equal to +.>
Figure SMS_69
. Then starting at the latest P point position, calculating the expansion length of the meshes of the second section by using the parameters corresponding to the second bracket section>
Figure SMS_70
And counting the number of meshes until the number of meshes is equal to +.>
Figure SMS_71
. Finally repeating the above steps for the third segment until the number of meshes is equal to +.>
Figure SMS_72
In this embodiment, the method further includes calculating a length of the non-uniform stent after densification in the vessel, including: after the far-end position of the non-uniform stent in the three-dimensional vascular model is obtained, calculating according to the central point data corresponding to the far-end position on the vascular central line and the corresponding stent segment parameters to obtain the pushing length of the virtual cylinder corresponding to the current central point, determining the central point position of the next virtual cylinder on the vascular central line according to the obtained pushing length, sequentially calculating the pushing length of each virtual cylinder, adopting the stent parameters corresponding to the next stent segment when calculating the expanding length of the next virtual cylinder when the number of the virtual cylinders subjected to the accumulating treatment is equal to the mesh number of the current stent segment, and re-accumulating the number of the virtual cylinders subjected to the accumulating treatment until all the virtual cylinders are processed, wherein the sum of the pushing lengths of the virtual cylinders is the expanding estimated length of the non-uniform stent after being pushed in the blood vessel.
Further, the calculating according to the central point data corresponding to the distal end position on the blood vessel central line and the corresponding bracket segment parameters to obtain the pushing length of the virtual cylinder corresponding to the current central point comprises the following steps: firstly, calculating according to central point data and corresponding support segment parameters to obtain the expansion length of a virtual cylinder corresponding to a current central point, then calculating according to corresponding support segment parameters to obtain the expansion diameter expansion upper limit of a support segment in an unconstrained state, then respectively extracting the three-dimensional blood vessel cross-section area equivalent diameter and the three-dimensional blood vessel cross-section perimeter equivalent diameter corresponding to the current central point according to the corresponding central point data, processing according to the expansion diameter expansion upper limit, the three-dimensional blood vessel cross-section area equivalent diameter and the three-dimensional blood vessel cross-section perimeter equivalent diameter to respectively obtain the expansion radius upper limit of the current virtual cylinder based on the area ratio definition adherence and the perimeter ratio definition adherence, and calculating according to the expansion radius upper limit and the expansion length by using an expansion radius model to obtain the expansion length of the corresponding virtual cylinder. And finally, calculating by adopting a bracket shortening model according to the pushing length of the virtual cylinder to obtain the pushing length of the virtual cylinder.
Specifically, unlike calculating the expansion length of the non-uniform stent in the blood vessel without the densification operation, when calculating the densification length of the stent in the blood vessel after the densification operation, in order to simulate the densification effect of the stent, it is necessary to calculate the expansion diameter densification upper limit of the stent in the unconstrained state.
According to the geometric characteristics of the braided stent, the diameter of the stent depends on the braiding angle
Figure SMS_73
The variation of (2) is expressed as:
Figure SMS_74
(4)
in the formula (4), theoretically
Figure SMS_75
The upper limit of (2) is 180 degrees, so that the calculation formula of the expansion diameter push-up upper limit of the non-uniform dense mesh braided stent in an unconstrained state is expressed as:
Figure SMS_76
(5)
specifically, because of the adherence of the stent, there are two defining ways: the area ratio or perimeter ratio of the stent section to the vessel section is calculated by using the upper limit of the compaction radius of each short cylinder:
Figure SMS_77
(6)
Figure SMS_78
(7)
in equations (6) and (7),
Figure SMS_79
representing the equivalent diameter of the three-dimensional blood vessel cross-section area corresponding to the current center point,/->
Figure SMS_80
And the equivalent diameter of the perimeter of the three-dimensional blood vessel section corresponding to the current center point is represented.
Given the geometry, mechanical properties of the stent itself and the interaction of the stent with the vessel wall in the vessel, stents often exhibit non-linear behavior during densification, namely: the stent is more difficult to push and close in a high adherence state than in a low adherence state, and the stent is more difficult to push and close in a large-diameter state than in a small-diameter state;
Therefore, when constructing the density pushing radius calculation formula, the variable density pushing rate is introduced, and the range of the variable density pushing rate is 0 to 1, and the density pushing radius model is expressed as:
Figure SMS_81
(8)
wherein:
Figure SMS_82
or (b)
Figure SMS_83
Figure SMS_84
In the formula (8) of the present invention,
Figure SMS_86
representing the current center point, +.>
Figure SMS_89
Represents the upper limit of the push radius,/, for>
Figure SMS_91
Indicating the length of stretch->
Figure SMS_87
Representing the equivalent diameter of the three-dimensional blood vessel cross-section area corresponding to the current center point,/->
Figure SMS_88
Represents the equivalent diameter of the perimeter of the three-dimensional blood vessel section corresponding to the current center point,/->
Figure SMS_90
Indicates the secret percentage,/, and->
Figure SMS_92
And->
Figure SMS_85
Is constant.
In one of the embodiments of the present invention,
Figure SMS_93
the value of (2) is in the range of 0 to 0.5, and preferably 0.5 can be taken. />
Figure SMS_94
The value of (2) is in the range of 0 to 1, and preferably 0.05 can be taken. />
Figure SMS_95
The value of (2) is in the range of 0 to 0.5, preferably 0.45./>
Figure SMS_96
The value of (2) is in the range of 0 to 1, and preferably 0.05 can be taken.
In the method for estimating the expansion length of the non-uniform stent in the blood vessel, a three-dimensional blood vessel model is constructed, the blood vessel center line and corresponding center point parameters are extracted, the model of the non-uniform stent to be implanted is obtained, the stent parameters are extracted correspondingly, the number of axial meshes of different stent sections corresponding to the non-uniform stent is calculated, the stent is discretely expressed into a plurality of coaxial short cylinders which are arranged along the blood vessel center line, after the distal end position of the stent expanding in the blood vessel is obtained, the expansion length of each short cylinder is calculated according to the stent section parameters corresponding to each short cylinder and the center point data, in the calculation process, the processing number of the short cylinders is accumulated, and when the accumulated number is equal to the number of the axial meshes of the corresponding stent section, the parameters of the lower stent section are adopted for calculation when the next short cylinder processing is carried out. The method can calculate the implanted length and the pushed length of the non-uniform dense mesh braided stent in real time, and the geometric structure, the mechanical property and the interaction of the stent and the vessel wall are considered in the pushing process, so that the result is accurate. Meanwhile, the method can reduce the clinical use threshold of the non-uniform dense mesh braided stent, reduce the operation difficulty of doctors, lighten the pressure and improve the operation effect.
It should be understood that, although the steps in the flowchart of fig. 1 are shown in sequence as indicated by the arrows, the steps are not necessarily performed in sequence as indicated by the arrows. The steps are not strictly limited to the order of execution unless explicitly recited herein, and the steps may be executed in other orders. Moreover, at least some of the steps in fig. 1 may include multiple sub-steps or stages that are not necessarily performed at the same time, but may be performed at different times, nor do the order in which the sub-steps or stages are performed necessarily performed in sequence, but may be performed alternately or alternately with at least a portion of other steps or sub-steps of other steps.
In one embodiment, as shown in fig. 4, there is provided a non-uniform stent deployment length estimation apparatus in a blood vessel, comprising: the central point data acquisition module 200, the designated stent parameter extraction module 210, the corresponding mesh number calculation module 220 of each stent segment, the stent discrete module 230, the first calculation module 240 of virtual cylinder expansion length, the second calculation module 250 of virtual cylinder expansion length and the estimated stent expansion length obtaining module 260, wherein:
The central point data acquisition module 200 is used for acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
a designated stent parameter extraction module 210, configured to obtain a model of a non-uniform stent implanted into a blood vessel, and extract relevant stent parameters from a stent database according to the model;
the mesh number calculation module 220 corresponds to each support segment, and is used for calculating the mesh number of each support segment in the axial direction according to the axial nominal length of each support segment and the axial diagonal nominal length of the grid in the support parameters, wherein the non-uniform support comprises a first support segment, a second support segment and a third support segment which are arranged along the axis;
a stent dispersing module 230, configured to disperse a non-uniform stent into a plurality of virtual cylinders sequentially arranged along the center line of the blood vessel, where the center point of each virtual cylinder coincides with the center line of the blood vessel;
the first calculation module 240 of the stretching length of the virtual cylinder is configured to obtain a distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculate according to center point data corresponding to the distal end position on the blood vessel center line and corresponding stent segment parameters to obtain a stretching length of the virtual cylinder corresponding to a current center point;
A second calculation module 250 for calculating the stretching length of the virtual cylinder, configured to determine the position of the center point of the next virtual cylinder on the blood vessel center line according to the obtained stretching length, sequentially calculate the stretching length of each virtual cylinder, and when the number of virtual cylinders processed by accumulation is equal to the mesh number of the current support section, adopt the support parameter corresponding to the next support section when calculating the stretching length of the next virtual cylinder, and re-accumulate the number of virtual cylinders processed by accumulation;
the stent deployment estimated length obtaining module 260 is configured to process all the virtual cylinders until the virtual cylinders are processed, and then sum of the deployment lengths of the virtual cylinders is the estimated length of deployment of the non-uniform stent in the blood vessel.
For specific limitations of the non-uniform stent deployment length estimation device in the blood vessel, reference may be made to the above limitations of the non-uniform stent deployment length estimation method in the blood vessel, and no further description is given here. The various modules in the non-uniform stent deployment length estimation device described above may be implemented in whole or in part by software, hardware, and combinations thereof. The above modules may be embedded in hardware or may be independent of a processor in the computer device, or may be stored in software in a memory in the computer device, so that the processor may call and execute operations corresponding to the above modules.
In one embodiment, a computer device is provided, which may be a server, the internal structure of which may be as shown in fig. 5. The computer device includes a processor, a memory, a network interface, and a database connected by a system bus. Wherein the processor of the computer device is configured to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, computer programs, and a database. The internal memory provides an environment for the operation of the operating system and computer programs in the non-volatile storage media. The database of the computer device is for storing stent database data. The network interface of the computer device is used for communicating with an external terminal through a network connection. The computer program is executed by a processor to implement a method of estimating a deployment length of a non-uniform stent in a vessel.
It will be appreciated by those skilled in the art that the structure shown in fig. 5 is merely a block diagram of some of the structures associated with the present application and is not limiting of the computer device to which the present application may be applied, and that a particular computer device may include more or fewer components than shown, or may combine certain components, or have a different arrangement of components.
In one embodiment, a computer device is provided comprising a memory and a processor, the memory having stored therein a computer program, the processor when executing the computer program performing the steps of:
acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
obtaining the model of a non-uniform stent implanted into a blood vessel, and extracting relevant stent parameters from a stent database according to the model;
the non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of the mesh in the support parameters;
dispersing the non-uniform stent into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, wherein the central point of each virtual cylinder coincides with the central line of the blood vessel;
acquiring the distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the stretching length of the virtual cylinder corresponding to the current central point;
Determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the bracket parameters corresponding to the next bracket section when calculating the stretching length of the next virtual cylinder when the number of the virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of the virtual cylinders subjected to accumulation processing;
and until all the virtual cylinders are processed, the sum of the stretching lengths of the virtual cylinders is the estimated length of the non-uniform stent stretching in the blood vessel.
In one embodiment, a computer readable storage medium is provided having a computer program stored thereon, which when executed by a processor, performs the steps of:
acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
obtaining the model of a non-uniform stent implanted into a blood vessel, and extracting relevant stent parameters from a stent database according to the model;
the non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of the mesh in the support parameters;
Dispersing the non-uniform stent into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, wherein the central point of each virtual cylinder coincides with the central line of the blood vessel;
acquiring the distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the stretching length of the virtual cylinder corresponding to the current central point;
determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the bracket parameters corresponding to the next bracket section when calculating the stretching length of the next virtual cylinder when the number of the virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of the virtual cylinders subjected to accumulation processing;
and until all the virtual cylinders are processed, the sum of the stretching lengths of the virtual cylinders is the estimated length of the non-uniform stent stretching in the blood vessel.
Those skilled in the art will appreciate that implementing all or part of the above described methods may be accomplished by way of a computer program stored on a non-transitory computer readable storage medium, which when executed, may comprise the steps of the embodiments of the methods described above. Any reference to memory, storage, database, or other medium used in the various embodiments provided herein may include non-volatile and/or volatile memory. The nonvolatile memory can include Read Only Memory (ROM), programmable ROM (PROM), electrically Programmable ROM (EPROM), electrically Erasable Programmable ROM (EEPROM), or flash memory. Volatile memory can include Random Access Memory (RAM) or external cache memory. By way of illustration and not limitation, RAM is available in a variety of forms such as Static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double Data Rate SDRAM (DDRSDRAM), enhanced SDRAM (ESDRAM), synchronous Link DRAM (SLDRAM), memory bus direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and memory bus dynamic RAM (RDRAM), among others.
The technical features of the above embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples merely represent a few embodiments of the present application, which are described in more detail and are not to be construed as limiting the scope of the invention. It should be noted that it would be apparent to those skilled in the art that various modifications and improvements could be made without departing from the spirit of the present application, which would be within the scope of the present application. Accordingly, the scope of protection of the present application is to be determined by the claims appended hereto.

Claims (9)

1. A method of estimating a deployed length of a non-uniform stent in a vessel, the method comprising:
acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, and extracting a blood vessel central line of a target area in the three-dimensional blood vessel model and central point data corresponding to each central point on the blood vessel central line;
obtaining the model of a non-uniform stent implanted into a blood vessel, and extracting relevant stent parameters from a stent database according to the model;
The non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of the mesh in the support parameters;
dispersing the non-uniform stent into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, wherein the central point of each virtual cylinder coincides with the central line of the blood vessel;
acquiring the distal end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the stretching length of the virtual cylinder corresponding to the current central point;
determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the bracket parameters corresponding to the next bracket section when calculating the stretching length of the next virtual cylinder when the number of the virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of the virtual cylinders subjected to accumulation processing;
And until all the virtual cylinders are processed, the sum of the stretching lengths of the virtual cylinders is the estimated length of the non-uniform stent stretching in the blood vessel.
2. The method for estimating a deployment length of a non-uniform stent in a blood vessel according to claim 1, wherein the calculating the deployment length of a virtual cylinder corresponding to the current center point according to the center point data corresponding to the distal end position on the blood vessel center line and the corresponding stent segment parameters comprises:
calculating by adopting a stretching radius model according to the center point data and the parameters of the corresponding support segments to obtain the stretching radius of the virtual cylinder corresponding to the current center point;
and calculating by adopting a bracket shortening model according to the stretching radius of the virtual cylinder to obtain the stretching length of the virtual cylinder.
3. The method of estimating a deployment length of a non-uniform stent in a vessel according to claim 2, wherein the deployment radius model is expressed as:
Figure QLYQS_1
in the above-mentioned description of the invention,
Figure QLYQS_2
representing the current center point, +.>
Figure QLYQS_3
Representing the center point +.>
Figure QLYQS_4
Corresponding three-dimensional vessel radius->
Figure QLYQS_5
Representing the center point +.>
Figure QLYQS_6
The stretching radius of the corresponding virtual cylinder, < ->
Figure QLYQS_7
Representing the upper limit of the deployment diameter of the implanted stent in the natural release state, wherein said R(s) is derived from said centre point data, said +. >
Figure QLYQS_8
Obtained from the parameters of the corresponding stent segments.
4. A method of estimating a deployed length of a non-uniform stent in a vessel according to claim 3, wherein the stent foreshortening model represents:
Figure QLYQS_9
in the above formula, the
Figure QLYQS_12
Representing stent diameter +.>
Figure QLYQS_15
The corresponding stretching length of the virtual cylinder, said +.>
Figure QLYQS_17
For the number of stent filaments, said +.>
Figure QLYQS_11
Is the side length of the bracket diamond lattice, which is +.>
Figure QLYQS_13
For the diameter of the stent, said +.>
Figure QLYQS_16
Is the diameter of the stent wire, wherein the +.>
Figure QLYQS_19
And->
Figure QLYQS_10
Derived from the stent parameters, said +.>
Figure QLYQS_14
Calculated from the stretching radius of the virtual cylinder, said +.>
Figure QLYQS_18
And calculating according to the bracket parameters.
5. The method of estimating a deployed length of a non-uniform stent in a vessel according to claim 4, further comprising calculating a length of the non-uniform stent after densification in the vessel, comprising:
after the distal end position of the non-uniform stent in the three-dimensional blood vessel model is obtained, calculating according to the central point data corresponding to the distal end position on the blood vessel central line and corresponding stent segment parameters to obtain the pushing length of the virtual cylinder corresponding to the current central point;
Determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained compaction length, sequentially calculating the compaction length of each virtual cylinder, adopting the support parameter corresponding to the next support section when calculating the stretching length of the next virtual cylinder when the number of virtual cylinders subjected to accumulation processing is equal to the mesh number of the current support section, and re-accumulating the number of virtual cylinders subjected to accumulation processing;
and until all the virtual cylinders are processed, the sum of the pushing lengths of the virtual cylinders is the estimated expanding length of the non-uniform stent after being pushed in the blood vessel.
6. The method for estimating a deployed length of a non-uniform stent in a blood vessel according to claim 5, wherein the calculating according to the central point data and the corresponding stent segment parameters corresponding to the distal end position on the central line of the blood vessel to obtain the compact length of the virtual cylinder corresponding to the current central point comprises:
calculating according to the center point data and the parameters of the corresponding support segments to obtain the stretching length of the virtual cylinder corresponding to the current center point;
calculating according to the parameters of the corresponding stent sections to obtain the expansion diameter pushing upper limit of the stent sections in an unconstrained state;
Respectively extracting the equivalent diameter of the three-dimensional blood vessel cross section area and the equivalent diameter of the three-dimensional blood vessel cross section perimeter corresponding to the current center point according to the data of the corresponding center point;
processing according to the expansion diameter pushing upper limit, the three-dimensional blood vessel cross-section area equivalent diameter and the three-dimensional blood vessel cross-section perimeter equivalent diameter to respectively obtain the pushing radius upper limit of the current virtual short cylinder based on the area ratio definition adherence and the perimeter ratio definition adherence;
calculating by using a secret radius model according to the secret radius upper limit and the stretching length to obtain a secret radius of a corresponding virtual cylinder;
and calculating by adopting a bracket shortening model according to the pushing radius of the virtual cylinder to obtain the pushing length of the virtual cylinder.
7. The method of estimating a deployed length of a non-uniform stent in a vessel according to claim 6, wherein the dense radius model is expressed as:
Figure QLYQS_20
wherein:
Figure QLYQS_21
or (b)
Figure QLYQS_22
Figure QLYQS_23
In the above-mentioned description of the invention,
Figure QLYQS_26
representing the current center point, +.>
Figure QLYQS_29
Represents the upper limit of the push radius,/, for>
Figure QLYQS_31
The length of the extension is indicated as such,
Figure QLYQS_25
represents the push radius of the virtual cylinder corresponding to the current center point, < >>
Figure QLYQS_28
Representing the equivalent diameter of the three-dimensional blood vessel cross-section area corresponding to the current center point,/- >
Figure QLYQS_30
Represents the equivalent diameter of the perimeter of the three-dimensional blood vessel section corresponding to the current center point,/->
Figure QLYQS_32
Indicates the secret percentage,/, and->
Figure QLYQS_24
And->
Figure QLYQS_27
Is constant.
8. A non-uniform stent deployment length estimation device in a vessel, the device comprising:
the central point data acquisition module is used for acquiring a three-dimensional blood vessel model related to an intracranial aneurysm blood vessel, extracting a blood vessel central line of a target area in the three-dimensional blood vessel model, and extracting central point data corresponding to each central point on the blood vessel central line;
the appointed stent parameter extraction module is used for obtaining the model of the non-uniform stent implanted into the blood vessel and extracting related stent parameters from a stent database according to the model;
the support sections correspond to mesh number calculation modules and are used for the non-uniform support, wherein the non-uniform support comprises a first support section, a second support section and a third support section which are arranged along an axis, and the mesh number in the axial direction of each support section is obtained by calculating the axial nominal length of each support section and the axial diagonal nominal length of a grid according to the support parameters;
the bracket discrete module is used for dispersing the non-uniform bracket into a plurality of virtual cylinders which are sequentially arranged along the central line of the blood vessel, and the central point of each virtual cylinder coincides with the central line of the blood vessel;
The first calculation module of the stretching length of the virtual cylinder is used for obtaining the far-end position of the non-uniform stent in the three-dimensional blood vessel model, and calculating according to the central point data corresponding to the far-end position on the blood vessel central line and the parameters of the corresponding stent segments to obtain the stretching length of the virtual cylinder corresponding to the current central point;
the second calculation module of the stretching length of the virtual cylinder is used for determining the central point position of the next virtual cylinder on the blood vessel central line according to the obtained stretching length, sequentially calculating the stretching length of each virtual cylinder, adopting the corresponding bracket parameter of the next bracket section when calculating the stretching length of the next virtual cylinder when the number of virtual cylinders subjected to accumulation processing is equal to the mesh number of the current bracket section, and re-accumulating the number of virtual cylinders subjected to processing;
and the stent expansion estimated length obtaining module is used for processing all the virtual cylinders until the virtual cylinders are processed, and the sum of the expansion lengths of the virtual cylinders is the expansion estimated length of the non-uniform stent in the blood vessel.
9. A computer device comprising a memory and a processor, the memory storing a computer program, characterized in that the processor implements the steps of the method of any of claims 1 to 7 when the computer program is executed.
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