CN116203222A - Blood detects uses equipment, analysis appearance and nutrition monitoring system - Google Patents

Blood detects uses equipment, analysis appearance and nutrition monitoring system Download PDF

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Publication number
CN116203222A
CN116203222A CN202310491968.8A CN202310491968A CN116203222A CN 116203222 A CN116203222 A CN 116203222A CN 202310491968 A CN202310491968 A CN 202310491968A CN 116203222 A CN116203222 A CN 116203222A
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CN
China
Prior art keywords
carrier
vibration
processing device
rotating
extrusion
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Granted
Application number
CN202310491968.8A
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Chinese (zh)
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CN116203222B (en
Inventor
欧阳勇航
苏辉
江鹏志
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hunan Aidiyou Medical Technology Co ltd
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Hunan Aidiyou Medical Technology Co ltd
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Priority to CN202310491968.8A priority Critical patent/CN116203222B/en
Publication of CN116203222A publication Critical patent/CN116203222A/en
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Publication of CN116203222B publication Critical patent/CN116203222B/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials

Abstract

The invention provides a blood detection device, an analyzer and a nutrition monitoring system. The blood detection equipment comprises a supporting table, a rotating ring, a carrier, a turnover device, a vibration treatment device and an extrusion treatment device. According to the blood detection equipment provided by the invention, the R1 reagent bottle is assembled in the placing cylinder in the corresponding carrier, the R2 reagent bottle is installed in the placing cylinder of the corresponding carrier, the rotating ring rotates to convey the reagent bottle and the R2 reagent bottle to the vibration treatment point and the extrusion treatment point, and the vibration and extrusion are completed through the vibration treatment device and the extrusion treatment device correspondingly, so that the solution drops into the test board, the vibration mixing of the reagent and the blood can be automatically realized, the drop into the test board is realized, and the efficiency of the test work is improved; the analyzer can detect the content of glycosylated hemoglobin in the sample to understand the condition of diabetes of the patient; the nutritional monitoring system is capable of printing out a instructional report based on nutritional diet instructional data.

Description

Blood detects uses equipment, analysis appearance and nutrition monitoring system
Technical Field
The invention relates to the field of diabetes detection and analysis, in particular to equipment for blood detection, an analyzer and a nutrition monitoring system.
Background
Diabetes is a metabolic disease characterized by hyperglycemia. Various methods for detecting diabetes, such as by detecting glycosylated hemoglobin in blood of a patient, typically the normal value of glycosylated hemoglobin ranges from 4% to 6%. It is also generally necessary to conduct a corresponding instruction of nutritional diet based on the detection result.
In the prior art, a conventional method for detecting glycosylated hemoglobin is to use boric acid affinity liquid chromatography. The test equipment used included a tester, a coded plate, a test plate, an R1 solvent (formulated from monobasic potassium phosphate, sodium hydroxide and sodium azide, pH 6.5) and an R2 solvent (formulated from glycine and sodium hydroxide, pH 9.5), with the R1 reagent bottle 12a containing the blood sample and the R1 solvent, and the R2 reagent bottle 12b containing the R2 solvent. During detection, the coded card is inserted on the tester. Then, as shown in (1 a) of fig. 1, the hand-held R1 reagent bottle 12a is vibrated to uniformly mix the blood with the R1 solvent, and then left to stand for two minutes after uniformly mixing; as shown in (1 b) of fig. 1, the uniformly mixed reagent was dropped into the groove in the center of the test plate 12c upside down, and left to stand for ten seconds; then, the reagent in the R2 reagent bottle 12b was dropped into the groove in the center of the test plate 12c, and after waiting for ten seconds, the test plate 12c was placed in a detection section in the tester and detected. Wherein, R1 reagent bottle and R2 reagent bottle all adopt the plastic extrusion bottle of flexible, need the hand to extrude the reagent bottle, and the liquid just can drip in the bottle.
However, when performing glycosylated hemoglobin measurement on a batch of blood samples, a tester needs to continuously shake the reagent by hand to uniformly mix the blood with the solvent, and squeeze the titration solvent, which is a great workload and a low measurement efficiency.
Accordingly, there is a need to provide a blood testing device, an analyzer, and a nutrition monitoring system that address the above-described issues.
Disclosure of Invention
The invention provides a blood detection device, which solves the technical problems of large workload and low detection efficiency when detecting a batch of blood samples.
In order to solve the above technical problems, the present invention provides a blood test apparatus comprising:
the support platform is provided with a placing groove structure;
the vibration processing device comprises a mounting frame, a motor, a driving wheel and a protruding shaft; the mounting frame is in sliding connection with the supporting table, the motor is fixedly arranged on the mounting frame, the driving wheel is fixed on an output shaft of the motor, and the protruding shaft is eccentrically arranged on the driving wheel;
the rotating ring is rotatably arranged on the supporting table and is positioned between the placing groove structure and the driving wheel;
the four carriers are arranged on the rotating ring in a surrounding mode, four liquid dropping holes are formed in the rotating ring, and the liquid dropping holes are arranged in one-to-one correspondence with the carriers;
the carrier comprises a slide bar, a mounting sleeve, a rotating shaft, a placement cylinder and a top cover, wherein the slide bar is mounted on the rotating ring, one end of the mounting sleeve is sleeved into the slide bar, the other end of the mounting sleeve is elastically connected with the top cover, the rotating shaft penetrates through the mounting sleeve and then is connected with the placement cylinder, and one liquid dropping hole is positioned below a corresponding placement cylinder;
the two insertion frames are respectively and correspondingly arranged on the two placing cylinders, and the connecting line of the two insertion frames passes through the circle center of the rotating ring;
when the rotating ring conveys the carrier to the position of the vibration treatment device, the driving device drives the convex shaft to be inserted into the insertion frame corresponding to the carrier so as to enable the carrier to enter a vibration state; the extrusion treatment device extrudes towards the structure direction of the placing groove;
when the rotating ring conveys the carrier from the vibration processing device to the extrusion processing device, the rotating shaft is driven to rotate by the turnover device, so that the placing cylinder is turned upside down; the extrusion treatment device extrudes towards the direction of the placing groove structure again.
Preferably, the extrusion processing device comprises a mounting plate, a telescopic cylinder and an extrusion rod, wherein the mounting plate is mounted on the supporting table, the telescopic cylinder is mounted on the mounting plate, one end of the extrusion rod is connected with an output shaft of the telescopic cylinder, and the other end of the extrusion rod faces the placing groove structure.
Preferably, the rotating ring comprises a rotating disc and a conical ring, and the supporting table comprises a base table and a circular boss;
the circular boss is arranged on the base, the rotating disc is arranged around the circular boss and is rotationally connected with the circular boss, the bevel gear ring is arranged on the top of the rotating disc, and the bevel gear ring is arranged around the circular boss;
wherein, the mounting frame and the mounting plate are both arranged on the circular boss, and the carrier and the liquid dropping hole are both arranged on the rotating disc; the driving wheel is a bevel gear, and the driving wheel can be meshed with the bevel gear ring.
Preferably, the driving device is a transmission arm, one end of the transmission arm is rotationally connected with the extrusion rod, and the other end of the transmission arm is rotationally connected with the mounting frame.
Preferably, the turnover device comprises a connecting frame, a toothed plate and a gear, wherein two ends of the connecting frame are respectively connected with the base station and the toothed plate, and the gear is arranged at one end of the rotating shaft, which is away from the placing cylinder.
Preferably, the top cover comprises a cover plate, a connecting shaft, an elastic piece and a piston block, wherein the piston block is embedded in the mounting sleeve, the bottom end of the connecting shaft stretches into the mounting sleeve and is connected with the piston block, the top end of the connecting shaft penetrates through the mounting sleeve and then is connected with the cover plate, and the elastic piece is arranged in the mounting sleeve and is located above the piston block.
Preferably, the top cover further comprises a sealant column, and the sealant column is inserted on the cover plate.
Preferably, an outer cover is mounted on the rotating disc, and covers the vibration processing device and the extrusion processing device; and through holes are formed in the outer cover at positions corresponding to the driving wheel and the extrusion rod.
The invention also provides an analyzer, which comprises an analyzer main machine and the blood detection equipment, wherein the supporting table is arranged on the outer wall of the analyzer main machine.
The invention also provides a nutrition monitoring system which comprises a data analysis module, a report output module and the analyzer;
the analyzer, the data analysis module and the report output module are connected in sequence in a signal mode.
In the blood test apparatus provided by the invention, the carrier comprises a first carrier, a second carrier, a third carrier and a fourth carrier. The first carrier and the second carrier are carriers provided with an insertion frame, the third carrier and the fourth carrier are carriers without an insertion frame, R1 reagent bottles are loaded in the first carrier and the second carrier, and R2 reagent bottles are loaded in the third carrier and the fourth carrier.
The rotating ring 3 can respectively convey the R1 reagent bottle and the R2 reagent bottle to the vibration treatment point and the extrusion treatment point, and the vibration of the R1 reagent bottle is completed through the vibration treatment device, so that the vibration mixing of the reagent and the blood is realized; the R1 reagent bottle and the R2 reagent bottle are sequentially extruded by the extrusion treatment device, so that the solution in the bottles is dripped into the test plate, finally, the vibration mixing of the reagent and blood and the automatic dripping into the test plate are automatically realized, the manual operation load is greatly reduced, and the efficiency of the test work of a plurality of groups of samples is improved.
Drawings
FIG. 1 is a schematic diagram of the prior art operation provided by the present invention, wherein (1 a) is a schematic diagram of shaking an R1 reagent bottle, (1 b) is a schematic diagram of dripping the solvent in the shaking R1 reagent bottle into a test plate, and (1 c) is a schematic diagram of dripping the solvent in the R2 reagent bottle into the test plate
FIG. 2 is a schematic diagram of a preferred structure of the analyzer according to the present invention;
FIG. 3 is a schematic view showing the structure of the blood test apparatus shown in FIG. 2 with the cover removed;
FIG. 4 is an enlarged schematic view of portion A shown in FIG. 3;
FIG. 5 is a cross-sectional view of the carrier shown in FIG. 3;
fig. 6 is a state diagram of a first working principle of the blood test apparatus, wherein (6 a) is a schematic diagram of an initial state, (6 b) is a schematic diagram of a rotating disc conveying an R1 reagent bottle and an R2 reagent bottle to be respectively moved above a vibration processing device and a placing groove structure, and (6 c) is a schematic diagram of a telescopic cylinder pushing a squeezing rod to squeeze the R2 reagent bottle, and a driving device drives a protruding shaft to be assembled with an insertion frame;
FIG. 7 is a schematic view showing the assembly of the male shaft and the insertion frame in the blood test apparatus shown in FIG. 3;
fig. 8 is a state diagram of a second working principle of the apparatus for blood test, wherein (8 a) is a schematic diagram of a state that the extrusion rod is extruded and separated from the R2 reagent bottle, (8 b) is a schematic diagram that the R2 reagent bottle and the R1 reagent bottle are conveyed by the rotating disc to be respectively moved above the vibration processing device and the placing groove structure, and (8 c) is a schematic diagram that the extrusion rod is pushed by the telescopic cylinder to extrude the R1 reagent bottle, and meanwhile, the driving device drives the protruding shaft to be assembled with the inserting frame;
FIG. 9 is a view showing a placement barrel of the blood test apparatus rotated one hundred eighty degrees, wherein (9 a) is a view showing the placement barrel facing upward, (9 b) is a view showing the placement barrel facing downward, (9 c) is a view showing a gear just engaged with a toothed plate, and (9 d) is a view showing the gear just disengaged from the toothed plate;
fig. 10 is a schematic diagram of a nutrition monitoring system provided by the present invention.
Reference numerals in the drawings:
2. the support table, 21, the base table, 22, the round boss, 211 and the placing groove structure;
3. a rotating ring 31, a rotating disc 32, a conical tooth ring 33 and a liquid dropping hole;
4. the vibration processing device 41, the mounting frame 42, the motor 43, the sliding rail 44, the driving wheel 45 and the protruding shaft;
5. the extrusion processing device 51, the mounting plate 52, the telescopic cylinder 53, the extrusion rod 54 and the extrusion rubber head;
6. the device comprises a carrier, 61, a slide bar, 62, a mounting sleeve, 63, a rotating shaft, 64, a placing cylinder, 65, a top cover, 641 and an elastic bulge;
651. the sealing device comprises a cover plate 652, a connecting shaft 653, an elastic piece 654, a piston block 655 and a sealing glue column;
7. an insertion frame;
8. a driving device;
9. the turnover device 91, the connecting frame 92, the toothed plate 93 and the gear;
10. an outer cover 101, a through hole;
11. extruding the bulge;
1. an analyzer main body 111 and a detection unit;
12a, R1 reagent bottles, 12b, R2 reagent bottles, 12c and a test plate.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention provides a blood test apparatus.
Referring to fig. 3 to 5 in combination, in an embodiment of the present invention, an apparatus for blood test includes:
a supporting table 2, wherein a placing groove structure 211 is arranged on the supporting table 2;
a vibration processing device 4, wherein the vibration processing device 4 comprises a mounting frame 41, a motor 42, a driving wheel 44 and a protruding shaft 45; the mounting frame 41 is slidably connected with the supporting table 2, the motor 42 is fixedly arranged on the mounting frame 41, the driving wheel 44 is fixed on an output shaft of the motor 42, and the protruding shaft 45 is eccentrically arranged on the driving wheel 44;
a rotating ring 3, wherein the rotating ring 3 is rotatably installed on the supporting table 2, and the rotating ring 3 is positioned between the placing groove structure 211 and the driving wheel 44;
the four carriers 6 are arranged on the rotating ring 3 in a surrounding manner, the rotating ring 3 is provided with four liquid dropping holes 33, and the liquid dropping holes 33 are arranged in one-to-one correspondence with the carriers 6;
the carrier 6 comprises a slide bar 61, a mounting sleeve 62, a rotating shaft 63, a placement cylinder 64 and a top cover 65, wherein the slide bar 61 is mounted on the rotating ring 3, one end of the mounting sleeve 62 is sleeved into the slide bar 61, the other end of the mounting sleeve 62 is elastically connected with the top cover 65, the rotating shaft 63 penetrates through the mounting sleeve 62 and then is connected with the placement cylinder 64, and one liquid dropping hole 33 is positioned below a corresponding placement cylinder 64;
the two insertion frames 7 are respectively and correspondingly arranged on the two placement cylinders 64, and the connecting line of the two insertion frames 7 passes through the circle center of the rotating ring 3;
when the rotating ring 3 conveys the carrier 6 to the position of the vibration processing device 4, the driving device 8 drives the convex shaft 45 to be inserted into the insertion frame 7 corresponding to the carrier 6 so as to make the carrier enter a vibration state; the extrusion processing device 5 extrudes towards the direction of the placing groove structure 211;
when the rotating ring 3 conveys the carrier 6 from the vibration processing device 4 to the extrusion processing device 5, the rotating shaft 63 is driven to rotate by the turnover device 9, so that the placing cylinder 64 is turned upside down; the extrusion device 5 is again extruded towards the placement groove structure 211.
In this embodiment, the placement groove structure 211 is used for placing the test board 12c. The R1 reagent bottle 12a contains the R1 solvent and the blood sample, and the R2 reagent bottle 12b contains the R2 solvent. It will be appreciated that the R1 reagent bottles 12a and R2 reagent bottles 12b are squeeze type reagent bottles (similar to eyedrop bottle structures) and can only titrate liquid when squeezed upside down.
The carriers 6 include a first carrier, a second carrier, a third carrier, and a fourth carrier. The first and second carriers are carriers 6 provided with an insertion frame 7, the third and fourth carriers are carriers 6 without an insertion frame 7, the first and second carriers are loaded with R1 reagent bottles 12a, and the third and fourth carriers are loaded with R2 reagent bottles 12b.
The rotating ring 3 can respectively convey the R1 reagent bottle 12a and the R2 reagent bottle 12b to a vibration treatment point and an extrusion treatment point, and vibration of the R1 reagent bottle 12a is completed through the vibration treatment device 4, so that uniform vibration mixing of the reagent and blood is realized; the R1 reagent bottle 12a and the R2 reagent bottle 12b are sequentially extruded by the extrusion processing device 5, so that the solution in the bottles is dripped into the test board 12, finally, the vibration mixing of the reagent and the blood and the automatic dripping into the test board 12 are automatically realized, the manual operation load is greatly reduced, and the efficiency of the test work of a plurality of groups of samples is improved.
Specifically, the working principle of the blood detection device is as follows:
step one:
referring to fig. 6 (6 a), in an initial state, the first carrier and the second carrier are disposed up and down, and the second carrier is located above the placement groove structure 211; the first carrier, the second carrier and the extrusion device 5 are positioned on the same straight line.
The third carrier and the fourth carrier are arranged left and right, and the fourth carrier is arranged towards the vibration processing device 4; the third carrier, the fourth carrier and the vibration processing device 4 are positioned on the same straight line.
Referring to fig. 6 (6 a) and (6 b), the rotating ring 3 conveys the fourth carrier to above the placement groove structure 211, and in this process, the turning device 9 drives the rotating shaft 63 of the fourth carrier to rotate, so that the placement cylinder 64 of the fourth carrier turns over, and the dropping end of the R2 reagent bottle 12b in the fourth carrier faces the test board 12c.
Referring to fig. 6 (6 c), the squeezing device 5 squeezes the R2 reagent bottles 12b in the fourth carrier to drop the R2 solvent into the test plate 12c, then takes out the test plate 12c, and supplements a new test plate 12c.
Referring to fig. 6 (6 c) and fig. 7 in combination, the first carrier is simultaneously conveyed to correspond to the vibration processing device 4; the driving device 8 drives the male shaft 45 to be inserted into the insertion frame 7 on the first carrier, and the vibration processing device 4 performs vibration processing on the R1 reagent bottle 12 a.
Step two:
referring to fig. 8 (8 a), the squeezing device 5 is pulled back and separated from the R2 reagent bottle 12b in the fourth carrier; after the R1 reagent bottle 12a in the first carrier is subjected to vibration treatment, the driving device 8 drives the vibration treatment device 4 to separate from the first carrier.
In this state, the third carrier and the fourth carrier are disposed up and down, and the fourth carrier is located above the placement groove structure 211; the third carrier, the fourth carrier and the extrusion device 5 are positioned on the same straight line.
The second carrier is arranged left and right with the first carrier, and the first carrier is arranged towards the vibration processing device 4; the second carrier, the first carrier and the vibration processing device 4 are positioned on the same straight line.
Please refer to fig. 8 (8 a) and (8 b); the rotating ring 3 conveys the first carrier to the upper part of the placing groove structure 211 and corresponds to the extrusion processing device 5; simultaneously, the overturning device 9 overturns the R1 reagent bottle 12a in the first carrier to enable the dripping end to face the test board 12c.
Referring to fig. 8 (8 c), the squeezing device 5 squeezes the R1 reagent bottles 12a in the first carrier to drop the R1 solvent into the test plate 12c;
meanwhile, the third carrier carries the R2 reagent bottles 12b and is transported to the vibration processing device 4, and at this time, the vibration processing device 4 does not process the R2 reagent bottles 12b in the third carrier.
Step three:
referring again to fig. 6 (6 a), the squeeze processing device 5 is pulled back and separated from the R1 reagent bottle 12a in the first carrier; the driving means 8 drive the vibration processing device 4 away from the third carrier.
In this state, the second carrier and the first carrier are disposed up and down, and the first carrier is located above the placement groove structure 211; the second carrier, the first carrier and the extrusion device 5 are positioned on the same straight line.
The fourth carrier and the third carrier are arranged left and right, and the third carrier is arranged towards the vibration processing device 4; the fourth carrier, the third carrier and the vibration processing device 4 are positioned on the same straight line.
Referring to fig. 6 (6 a) and (6 b), the rotating ring 3 rotates again, the R2 reagent bottles 12b for conveying the third carrier are conveyed to the upper side of the placing groove structure 211 by the vibration processing device 4, and correspond to the extrusion processing device 5, and the turning device 9 drives the dripping ends of the R2 reagent bottles 12b of the third carrier to face the test board 12c;
referring again to fig. 6 (6 c), the squeezing device 5 squeezes the R2 solvent in the R2 reagent bottle 12b of the third carrier into the test plate 12c. The test plate 12c is then removed and a new test plate 12c is replenished.
Wherein, the test board 12c after taking out is sent to the test equipment for testing.
Simultaneously, the R1 reagent bottle 12a newly loaded in the first carrier is again transferred to the vibration processing device 4, and the above steps are circulated.
In this embodiment, when the R1 reagent bottle 12a and the R2 reagent bottle 12b are subjected to squeeze titration by the squeeze processing device 5, they can be taken out from the corresponding carrier 6 and replaced with new reagent bottles. Can be taken out and replaced in a bottle-by-bottle mode; or after four reagent bottles are extruded and titrated, the four reagent bottles can be taken out and replaced uniformly.
Referring again to fig. 7, the vibration principle of the vibration processing apparatus 4 is as follows:
when the carrier 6 conveys the R1 reagent bottle 12a to move to the position of the vibration processing device 4, the driving device 8 pushes the mounting frame 41 to enable the protruding shaft 45 to be inserted into the insertion frame 7 at the front side of the placement barrel 64, the motor 42 drives the driving wheel 44 to rotate, the protruding shaft 45 follows the eccentric rotation and drives the insertion frame 7 to vibrate, and the insertion frame 7 drives the placement barrel 64 to vibrate, so that the vibration work of the R1 reagent bottle 12a is completed.
Referring to fig. 5, in the present embodiment, a plurality of elastic protrusions 641 are disposed inside the placement barrel 64. Preferably, the elastic protrusions 641 are made of rubber or silicone rubber.
After the R1 reagent bottle 12a or the R2 reagent bottle 12b is set, the elastic projection 641 is micro-pressed, so that the R1 reagent bottle 12a or the R2 reagent bottle 12b can be stably mounted inside the setting cylinder 64.
In other embodiments, the placement barrel 64 may be sized to provide an interference fit connection of the placement barrel 64 with the body of the R1 reagent bottle 12a or the R2 reagent bottle 12b.
Referring to fig. 3, the extrusion device 5 includes a mounting plate 51, a telescopic cylinder 52 and an extrusion rod 53, the mounting plate 51 is mounted on the supporting table 2, the telescopic cylinder 52 is mounted on the mounting plate 51, one end of the extrusion rod 53 is connected with an output shaft of the telescopic cylinder 52, and the other end of the extrusion rod 53 faces the placement groove structure 211.
The telescopic cylinder 52 pushes the extrusion rod 53 to compress the R1 reagent bottle 12a or the R2 reagent bottle 12b, so that the solution drops into the groove in the center of the test plate 12c, and the preparation work of detection and analysis is completed.
As a preferable mode of this embodiment, an end of the extrusion rod 53 away from the telescopic cylinder 52 is provided with an extrusion head 54, and by providing the extrusion head 54, the extrusion rod 53 is in soft contact with the R1 reagent bottles 12a and 12b.
In the present embodiment, the telescopic cylinder 52 may be a hydraulic cylinder, an air cylinder, or an electric telescopic cylinder.
Referring to fig. 3 and 7 in combination, in the present embodiment, the rotating ring 3 includes a rotating disc 31 and a bevel gear ring 32, and the supporting table 2 includes a base 21 and a circular boss 22;
the circular boss 22 is arranged on the base 21, the rotating disc 31 is arranged around the circular boss 22 and is in rotating connection with the circular boss 22, the bevel ring 32 is arranged on the top of the rotating disc 31, and the bevel ring 32 is arranged around the circular boss 22;
wherein, the mounting frame 41 and the mounting plate 51 are both mounted on the circular boss 22, and the carrier 6 and the drip hole 33 are both disposed on the rotating disc 31; the drive wheel 44 is a bevel gear, and the drive wheel 44 is capable of meshing with the bevel gear ring 32.
When the rotating ring 3 is required to be driven to switch the carrier 6 to different treatment positions, the driving wheel 44 is meshed with the bevel gear ring 32, and the motor 42 drives the driving wheel 44 to rotate to drive the bevel gear ring 32 to rotate, so that the rotating disc 31 is driven to rotate ninety degrees to drive the carrier 6 to different treatment positions.
When the carrier 6 rotates to the position of the vibration processing device 4 carrying the R1 reagent bottle 12a, the driving device 8 pushes the mounting frame 41, drives the motor 42 to move towards the carrier 6, and drives the driving wheel 44 to be separated from the bevel ring 32.
Meanwhile, the protruding shaft 45 eccentrically arranged at the end part of the driving wheel 44 is inserted into the insertion frame 7, so that when the motor 42 drives the driving wheel 44 to rotate, the protruding shaft 45 is matched with the insertion frame 7 to drive the placing cylinder 64 to vibrate, so that blood and R1 reagent are uniformly mixed, and the motor 42 is utilized to drive the rotary conveying carrier 6 of the rotary disk 31 to different processing points and realize the vibration function under different states.
As a preferable mode of this embodiment, the time of each vibration is the same, that is, the number of revolutions of the motor 42 driving the driving wheel 44 to rotate is the same, after each rotation of the driving wheel 44 is stopped, the tooth slot on the driving wheel 44 is just corresponding to the tooth on the bevel ring 32, and the protruding shaft 45 is located below the driving wheel 44 again, and the center of the protruding shaft 45 is the same as the center of the insert frame 7.
Referring again to fig. 7, in the present embodiment, the circumferential side surface of the circular boss 22 is provided with an annular protrusion, and the inner wall of the rotating disc 31 is provided with an annular groove; the annular groove is assembled with the annular protrusion to realize running fit.
As a preferable mode of the present embodiment, a supporting wheel is provided at the bottom of the rotating disc 31, so as to support the rotating disc 31 in an auxiliary manner, thereby improving stability.
It will be appreciated that in other embodiments, the driving wheel 44 may not be a bevel gear, and the bevel gear ring 32 may be engaged with a bevel gear of the external driving device 8 to complete rotation of the driving wheel 44 by the bevel gear ring 32.
Referring to fig. 4, in this embodiment, the vibration processing device 4 further includes a sliding rail 43, the sliding rail 43 is mounted on the circular boss 22, and a sliding block is disposed on the mounting frame 41, and the sliding block is assembled with the sliding rail 43 to achieve a sliding fit.
In other embodiments, the circular boss 22 may also be horizontally provided with a sliding rod, and the bottom of the mounting frame 41 is sleeved on the sliding rod.
Referring to fig. 3, in this embodiment, the driving device 8 is a transmission arm, one end of the transmission arm is rotatably connected to the extrusion rod 53, and the other end of the transmission arm is rotatably connected to the mounting frame 41.
When the telescopic cylinder 52 pushes the extrusion rod 53 to extrude the R2 reagent to drop onto the test board 12c, the transmission arm is driven to push the mounting frame 41, the motor 42 is driven to move, and the protruding shaft 45 at the end of the driving wheel 44 is inserted into the insertion frame 7 at the front side of the placement barrel 64 at the vibration processing device 4.
Then, the motor 42 drives the driving wheel 44 to rotate to complete the vibration work of mixing the R1 reagent and the blood, and no driving device is needed to be additionally arranged, so that the cost is reduced.
Wherein, after the squeeze rod 53 squeezes the R2 reagent bottle 12b, the squeeze rod 53 can be retracted slightly after the liquid drops out, reducing the pressure on the R2 reagent bottle 12b, and the protruding shaft 45 is still located in the insertion frame 7.
It will of course be appreciated that in other embodiments the drive means 8 may be a pneumatic cylinder, hydraulic cylinder, electric telescopic cylinder or the like.
Referring to fig. 3 and 5 in combination, the turning device 9 includes a connecting frame 91, a toothed plate 92, and a gear 93, wherein two ends of the connecting frame 91 are respectively connected to the base 21 and the toothed plate 92, and the gear 93 is disposed at one end of the rotating shaft 63 facing away from the placement cylinder 64.
Referring to fig. 5 and 9 in combination, by arranging the gear 93 on the rotating shaft 63 to cooperate with the toothed plate 92, when the rotating disc 31 rotates, the carrier 6 drives the gear 93 to mesh with the toothed plate 92, the rotating disc 31 continues to rotate, and the gear 93 rotates with the toothed plate 92 to drive the placing cylinder 64 to rotate by one hundred eighty degrees, so that no additional driving device such as a motor is required for driving the placing cylinder 64 to rotate, thereby reducing cost.
The toothed plate 92 is preferably an arc-shaped toothed plate, and the arc is identical to the arc of the rotating disk 31.
In an embodiment, the rotating shaft 63 penetrates through the mounting sleeve 62, and a rubber sleeve is arranged on the surface of the rotating shaft 63 to increase friction between the rotating shaft and the mounting sleeve 62, so that the rotating shaft can not rotate randomly under the action of external force.
The number of the connecting frames 91 is two, and the two connecting frames 91 are positioned at two sides of the placing groove structure 211. After the carrier 6 is processed by the extrusion processing device 5, the gear 93 acts on the toothed plate 92 again to drive the placement cylinder 64 to rotate to the one hundred eighty degrees to the original position again.
In another embodiment, a coil spring may be disposed on the rotating shaft 63, an inner end of the coil spring is connected with the rotating shaft 63, an outer end of the coil spring is connected with a circular cover disposed on the mounting sleeve 62, and the coil spring is used for limiting the rotating shaft 63.
At this time, the connection frame 91 is provided one between the placement groove structure 211 and the vibration processing device 4.
At this time, one toothed plate 92 is provided, and when the gear 93 moves to the last tooth of the toothed plate 92, the placement cylinder 64 rotates one hundred eighty degrees, and at this time the output ends of the R1 reagent bottles 12a and R2 reagent bottles 12b face the groove in the center of the test plate 12c in the placement groove structure 211.
When the rotating disc 31 drives the gear 93 to be completely staggered with the toothed plate 92, the placing cylinder 64 is driven to rotate for one hundred eighty degrees to the original position by the action of the coil spring.
In another embodiment, the turning device 9 may also be a driving motor, and an output shaft of the driving motor is fixedly connected to the rotating shaft 63, so as to drive the rotating shaft 63 to rotate.
Referring to fig. 5 again, in an embodiment, the top cover 65 includes a cover plate 651, a connecting shaft 652, an elastic member 653 and a piston block 654, the piston block 654 is embedded in the mounting sleeve 62, the bottom end of the connecting shaft 652 extends into the mounting sleeve 62 and is connected with the piston block 654, the top end of the connecting shaft 652 penetrates through the mounting sleeve 62 and is connected with the cover plate 651, and the elastic member 653 is disposed in the mounting sleeve 62 and is located above the piston block 654.
Preferably, the elastic member 653 is sleeved on the connection shaft 652.
When the R1 reagent bottle 12a or the R2 reagent bottle 12b is placed in the placement cylinder 64, the cover plate 651 is lifted, the piston block 654 is pulled by the cover plate 651 through the connecting shaft 652 to compress the elastic member 653, and the cover plate 651 can stably limit the R1 reagent bottle 12a or the R2 reagent bottle 12b through the elastic thrust of the elastic member 653.
In other embodiments, the cover plate 651 can also be directly coupled to the top of the mounting sleeve 62 by a resilient member 653.
The elastic member 653 is preferably a spring, or may be an elastic member such as a reed.
Referring to fig. 5, the top cover 65 further includes a sealant post 655, and the sealant post 655 is inserted into the cover plate 651.
Through setting up sealant post 655, after R1 reagent bottle 12a and R2 reagent bottle 12b are corresponding to be installed in placing barrel 64, its output is plugged through sealant post 655, improves the leakproofness of shutoff, and sealant post 655 directly inserts on apron 651, can directly change after the use, avoids appearing cross contamination.
The sealant post 655 is made of rubber or silica gel.
The assembly holes are correspondingly formed in the cover plate 651, the flanges are arranged on the surfaces of the sealant columns 655, when the flanges are in contact with the top of the cover plate 651, the bottom ends of the sealant columns 655 are flush with the bottom of the cover plate 651, and the sealant columns 655 are in interference fit with the assembly holes.
Referring to fig. 1, a cover 10 is mounted on the rotating disc 31, and the cover 10 covers the vibration processing device 4 and the extrusion processing device 5. Through holes 101 are formed in the outer cover 10 at positions corresponding to the driving wheel 44 and the pressing rod 53.
The extrusion processing device 5 and the vibration processing device 4 can be protected in a packaged manner by arranging the outer cover 10, and the aesthetic degree of the whole equipment is improved.
A squeeze protrusion 11 is provided on the housing 10 between the driving wheel 44 and the squeeze head 54, and the squeeze protrusion 11 is used for squeezing the reagent bottle to squeeze out bubbles inside the reagent bottle.
By providing the pressing protrusions 11, when the R1 reagent bottles 12a and R2 reagent bottles follow the rotation of the rotation disk 31, the pressing protrusions 11 contact and press the surfaces of the R1 reagent bottles 12a and R2 reagent bottles 12b, squeezing out the air bubbles inside.
The invention also provides an analyzer.
Referring to fig. 2, the analyzer includes the blood testing device and an analyzer main body 1, and the support table 2 is disposed on an outer wall of the analyzer main body 1.
Wherein, the lower right corner of the analyzer mainframe 1 is provided with a detection part 111, and after the cover plate 651 on the detection part 111 is opened, the test plate 12c is put into the interior to detect the content of glycosylated hemoglobin of the sample, so as to know the condition of diabetes of the patient.
Preferably, the analyzer main unit 1 is provided with a touch display screen, so as to facilitate the test operation of the analyzer main unit 1 and display the detection result.
The invention also provides a nutrition monitoring system.
Referring to fig. 10, the nutrition monitoring system includes the analyzer, a data analysis module and a report output module;
the analyzer, the data analysis module and the report output module are connected in sequence in a signal mode.
The data analysis module is used for processing the index data provided by the analyzer and outputting corresponding nutrition diet guide data according to the analysis result.
The report output module is used for printing and outputting a guide report according to the nutritional diet guide data.
The foregoing description is only illustrative of the present invention and is not intended to limit the scope of the invention, and all equivalent structures or equivalent processes or direct or indirect application in other related technical fields are included in the scope of the present invention.

Claims (10)

1. A blood test apparatus comprising:
the support platform is provided with a placing groove structure;
the vibration processing device comprises a mounting frame, a motor, a driving wheel and a protruding shaft; the mounting frame is in sliding connection with the supporting table, the motor is fixedly arranged on the mounting frame, the driving wheel is fixed on an output shaft of the motor, and the protruding shaft is eccentrically arranged on the driving wheel;
the rotating ring is rotatably arranged on the supporting table and is positioned between the placing groove structure and the driving wheel;
the four carriers are arranged on the rotating ring in a surrounding mode, four liquid dropping holes are formed in the rotating ring, and the liquid dropping holes are arranged in one-to-one correspondence with the carriers;
the carrier comprises a slide bar, a mounting sleeve, a rotating shaft, a placement cylinder and a top cover, wherein the slide bar is mounted on the rotating ring, one end of the mounting sleeve is sleeved into the slide bar, the other end of the mounting sleeve is elastically connected with the top cover, the rotating shaft penetrates through the mounting sleeve and then is connected with the placement cylinder, and one liquid dropping hole is positioned below a corresponding placement cylinder;
the two insertion frames are respectively and correspondingly arranged on the two placing cylinders, and the connecting line of the two insertion frames passes through the circle center of the rotating ring;
when the rotating ring conveys the carrier to the position of the vibration treatment device, the driving device drives the convex shaft to be inserted into the insertion frame corresponding to the carrier so as to enable the carrier to enter a vibration state; the extrusion treatment device extrudes towards the structure direction of the placing groove;
when the rotating ring conveys the carrier from the vibration processing device to the extrusion processing device, the rotating shaft is driven to rotate by the turnover device, so that the placing cylinder is turned upside down; the extrusion treatment device extrudes towards the direction of the placing groove structure again.
2. The apparatus for blood test as set forth in claim 1, wherein the squeeze processing device includes a mounting plate mounted on the support table, a telescopic cylinder mounted on the mounting plate, and a squeeze rod having one end connected to an output shaft of the telescopic cylinder and the other end directed toward the placement groove structure.
3. The apparatus for blood test as claimed in claim 2, wherein the rotary ring includes a rotary disk and a conical ring, and the support stand includes a base stand and a circular boss;
the circular boss is arranged on the base, the rotating disc is arranged around the circular boss and is rotationally connected with the circular boss, the bevel gear ring is arranged on the top of the rotating disc, and the bevel gear ring is arranged around the circular boss;
wherein, the mounting frame and the mounting plate are both arranged on the circular boss, and the carrier and the liquid dropping hole are both arranged on the rotating disc; the driving wheel is a bevel gear, and the driving wheel can be meshed with the bevel gear ring.
4. The apparatus for blood test as set forth in claim 2, wherein the driving means is a transmission arm, one end of which is rotatably connected to the pressing rod, and the other end of which is rotatably connected to the mounting frame.
5. The apparatus for blood test as set forth in claim 3, wherein the turning device comprises a connecting frame, a toothed plate and a gear, wherein both ends of the connecting frame are respectively connected with the base and the toothed plate, and the gear is disposed at one end of the rotating shaft facing away from the placement cylinder.
6. The apparatus for blood test as set forth in claim 1, wherein the top cover includes a cover plate, a connecting shaft, an elastic member and a piston block, the piston block is embedded in the mounting sleeve, the bottom end of the connecting shaft extends into the mounting sleeve and is connected with the piston block, the top end of the connecting shaft penetrates through the mounting sleeve and is connected with the cover plate, and the elastic member is arranged in the mounting sleeve and is located above the piston block.
7. The apparatus for blood test as recited in claim 6, wherein the top cover further comprises a sealant post, the sealant post being inserted over the cover plate.
8. The apparatus for blood test according to claim 2, wherein a cover is mounted on the rotating disk, the cover covering the vibration processing device and the pressing processing device; and through holes are formed in the outer cover at positions corresponding to the driving wheel and the extrusion rod.
9. An analyzer comprising an analyzer main body and the blood test apparatus according to any one of claims 1 to 8, wherein the support base is provided on an outer wall of the analyzer main body.
10. A nutrition monitoring system comprising a data analysis module, a report output module, and the analyzer of claim 9;
the analyzer, the data analysis module and the report output module are connected in sequence in a signal mode.
CN202310491968.8A 2023-05-05 2023-05-05 Blood detects uses equipment, analysis appearance and nutrition monitoring system Active CN116203222B (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5305650A (en) * 1990-10-29 1994-04-26 Ajinomoto Co., Inc. Automatic preparation apparatus
JP2005042764A (en) * 2003-07-24 2005-02-17 Koyo Seiko Co Ltd Tapered roller bearing device for wheel, and method for assembling the same
CN102673990A (en) * 2012-05-24 2012-09-19 华嘉利自动机械(昆山)有限公司 Modular same-direction vibration aligner and alignment unit
US20180246132A1 (en) * 2015-08-28 2018-08-30 Hitachi High-Technologies Corporation Automatic analyzer and reagent bottle loading method
CN114471273A (en) * 2022-01-24 2022-05-13 郝剑南 Dilution system for medical reagent sample liquid inspection and use method thereof
CN115055090A (en) * 2022-08-19 2022-09-16 北京安吉贝玛健康科技有限公司 Nursing is with rotatory flexible parcel location type medicine oscillator of formula of extruding

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5305650A (en) * 1990-10-29 1994-04-26 Ajinomoto Co., Inc. Automatic preparation apparatus
JP2005042764A (en) * 2003-07-24 2005-02-17 Koyo Seiko Co Ltd Tapered roller bearing device for wheel, and method for assembling the same
CN102673990A (en) * 2012-05-24 2012-09-19 华嘉利自动机械(昆山)有限公司 Modular same-direction vibration aligner and alignment unit
US20180246132A1 (en) * 2015-08-28 2018-08-30 Hitachi High-Technologies Corporation Automatic analyzer and reagent bottle loading method
CN114471273A (en) * 2022-01-24 2022-05-13 郝剑南 Dilution system for medical reagent sample liquid inspection and use method thereof
CN115055090A (en) * 2022-08-19 2022-09-16 北京安吉贝玛健康科技有限公司 Nursing is with rotatory flexible parcel location type medicine oscillator of formula of extruding

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