CN116172613A

CN116172613A - Method for determining region of interest in ultrasound image and ultrasound imaging device

Info

Publication number: CN116172613A
Application number: CN202111425699.2A
Authority: CN
Inventors: 刘梦斐; 罗英州
Original assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Current assignee: Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date: 2021-11-26
Filing date: 2021-11-26
Publication date: 2023-05-30

Abstract

The embodiment of the application provides a method for determining a region of interest in an ultrasonic image and ultrasonic imaging equipment, wherein the method comprises the steps of acquiring an ultrasonic image of uterus and displaying the ultrasonic image of uterus through a display interface of a display; determining a first characteristic point of endometrium in the uterine ultrasonic image, wherein the first characteristic point comprises a characteristic point positioned at a cervix uteri and a characteristic point positioned at a uterine fundus; according to the trend of the endometrium, automatically connecting the first characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus to form an endometrium boundary line of the endometrium; and determining at least the area between the endometrium boundary lines in the uterine ultrasound image as the region of interest. The method and the device can improve the accuracy and the efficiency of determining the region of interest which is tangential to the shape of the endometrium/binding band.

Description

Method for determining region of interest in ultrasound image and ultrasound imaging device

Technical Field

The application relates to the technical field of medical equipment, in particular to a method for determining a region of interest in an ultrasonic image and ultrasonic imaging equipment.

Background

Endometrial receptivity refers to the ability of the endometrium to receive fertilized eggs in a state that allows the blastocyst to locate, adhere, invade and remodel the endometrium to cause implantation of the embryo. The accurate evaluation of the endometrial receptivity has important clinical significance in the aspects of actually selecting planting time, evaluating pregnancy rate and the like, and is an important ring in the current reproduction evaluation standard system.

The peristaltic wave of endometrium refers to the mechanical wave generated by the contraction of the combination band at the junction of the myometrium and the endometrium to drive the endometrium to peristaltic. The frequency, direction, intensity and the like of the endometrial peristaltic wave or the combined band peristaltic wave are changed along with menstrual cycle changes, so that sperm transportation and embryo implantation are assisted, and the method is one of important indexes for judging the endometrial receptivity. Meanwhile, the uterine peristalsis law is influenced by uterine diseases, so that the research on peristaltic waves has the potential value of assisting in diagnosing uterine diseases.

The prior art scheme performs qualitative and quantitative analysis on endometrial peristaltic waves, but due to complex and disordered movement in the uterus (outside the endometrium), the peristaltic waves can be influenced by intestinal peristalsis, respiration and the like, visual interference is caused on observation, display and the like of the peristaltic conditions of the endometrium or the binding band, so that the interference of movement of a non-interested region is eliminated, and the observation range is locked in the endometrium or the binding band region only.

Disclosure of Invention

The application provides a method for determining a region of interest in an ultrasonic image and ultrasonic imaging equipment, aiming at improving the accuracy and efficiency of determining the region of interest which is matched with the shape of an endometrium/bonding belt.

In a first aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

acquiring a uterine ultrasound image and displaying the uterine ultrasound image through a display interface of a display;

determining a first characteristic point of endometrium in the uterine ultrasonic image, wherein the first characteristic point comprises a characteristic point positioned at a cervix uteri and a characteristic point positioned at a uterine fundus;

according to the trend of the endometrium, automatically connecting the first characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus to form an endometrium boundary line of the endometrium;

and determining at least the area between the endometrium boundary lines in the uterine ultrasound image as the region of interest.

In a second aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

automatically connecting the first characteristic points one by one from the characteristic points at one end of the endometrium to the characteristic points at the other end of the endometrium according to the trend of the endometrium to form an endometrium boundary line of the endometrium, wherein one end of the endometrium is the cervix uteri, the other end of the endometrium is the fundus, or one end of the endometrium is the fundus, and the other end of the endometrium is the cervix uteri;

In a third aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

according to the trend of the endometrium, automatically connecting the characteristic points of the first side endometrium of the endometrium one by one from the characteristic points of one end to the characteristic points of the other end to form a first side endometrium boundary line;

According to the trend of the endometrium, automatically connecting the characteristic points of the second side endometrium of the endometrium one by one from the characteristic points of the other end to the characteristic points of one end to form a second side endometrium boundary line;

wherein the first side endomembrane is a endometrial membrane, the second side endomembrane is a endometrial membrane, or the first side endomembrane is a endometrial membrane, and the second side endomembrane is a endometrial membrane;

determining a region between at least the first side intima boundary line and the second side intima boundary line in the uterine ultrasound image as the region of interest.

In a fourth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

determining a second feature point in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature point comprises a feature point positioned at the cervix and a feature point positioned at the fundus;

according to the trend of the endometrium, automatically connecting the second characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus to form a uterine cavity line of the endometrium;

Generating a anterior membrane boundary line and a posterior membrane boundary line based on the uterine cavity line;

and determining at least a region between the anterior membrane boundary line and the posterior membrane boundary line in the uterine ultrasound image as the region of interest.

In a fifth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

generating a anterior membrane boundary line and/or a posterior membrane boundary line based on the uterine cavity line;

and determining the region between any two of at least the anterior membrane boundary line, the posterior membrane boundary line and the uterine cavity line in the uterine ultrasound image as the region of interest.

In a sixth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

generating a uterine cavity line based on an endometrium boundary line of the endometrium;

and determining at least the area between the endometrium boundary line and the uterine cavity line in the uterine ultrasound image as the region of interest.

In a seventh aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

determining a first characteristic point of a first side endometrium of the endometrium ultrasonic image, wherein the first characteristic point comprises a characteristic point positioned at a cervix and a characteristic point positioned at a fundus; wherein the first side endometrium comprises the pre-or post-endometrium of the endometrium;

According to the trend of the endometrium, automatically connecting the first characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus to form a first boundary line of the first side endometrium;

generating a second boundary line from the first boundary line away from the first lateral intima and proximate to the myometrium;

determining a region between at least the first boundary line and the second boundary line in the uterine ultrasound image as the region of interest.

In an eighth aspect, an embodiment of the present application provides a method for determining a region of interest in an ultrasound image, including:

determining a third characteristic point of endometrium in the uterine ultrasonic image, wherein the third characteristic point comprises a characteristic point positioned at a cervix uteri and a characteristic point positioned at a uterine fundus;

according to the trend of the endometrium, the third characteristic points are automatically connected one by one according to the shortest path to form an endometrium boundary line of the endometrium;

In a ninth aspect, embodiments of the present application provide an ultrasound imaging apparatus, including:

A probe;

a transmitting circuit that excites the probe to transmit ultrasound waves to the uterus;

the receiving circuit controls the probe to receive the ultrasonic echo so as to obtain an ultrasonic echo signal;

a display providing a display interface;

the ultrasonic imaging equipment processes the ultrasonic echo signals to obtain uterine ultrasonic images; and executing the method for determining the region of interest in the ultrasound image, wherein the region of interest is determined in the uterine ultrasound image;

the ultrasonic imaging equipment is also used for extracting and processing ultrasonic echo signals of the region of interest to obtain peristaltic motion parameters of the region of interest; and displaying a chart of the peristaltic movement parameters of the region of interest over time through a display interface of the display.

In a ninth aspect, embodiments of the present application provide a computer readable storage medium storing a computer program, which when executed by a processor causes the processor to implement the method described above.

The embodiment of the application provides a method for determining a region of interest in an ultrasonic image and ultrasonic imaging equipment, wherein the method comprises the steps of determining a first characteristic point of an endometrium in an ultrasonic image of a uterus, automatically connecting the first characteristic point according to the trend of the endometrium to form an endometrium boundary line of the endometrium, so that the boundaries of the region of interest on two sides of the endometrium can be determined according to the determined endometrium boundary line; meanwhile, the first characteristic points comprise characteristic points positioned at the cervix uteri and characteristic points positioned at the fundus, and can limit the endpoints of the boundary line of the inner membrane at the cervix uteri and the fundus; the method can more accurately identify the region of interest in the uterine ultrasound image, eliminate interference of movement outside the region of interest on observation and analysis of peristalsis, and better lock the observation range in the endometrial or binding band region only.

It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the disclosure of embodiments of the present application.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present application, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

Fig. 1 is a flowchart of a method for determining a region of interest in an ultrasound image according to an embodiment of the present application;

FIG. 2 is a schematic block diagram of an ultrasound imaging device in one embodiment;

FIG. 3 is a schematic diagram of detection of peristaltic waves, for example, in one embodiment;

FIGS. 4-8 are schematic diagrams of determining a region of interest in various embodiments;

FIG. 9 is a flowchart of a method for determining a region of interest in an ultrasound image according to another embodiment of the present application;

FIG. 10 is a flowchart of a method for determining a region of interest in an ultrasound image according to another embodiment of the present application;

FIG. 11 is a flowchart illustrating a method for determining a region of interest in an ultrasound image according to another embodiment of the present application;

FIGS. 12-15 are schematic diagrams of determining a region of interest in various embodiments;

FIG. 16 is a flowchart of a method for determining a region of interest in an ultrasound image according to yet another embodiment of the present application;

FIG. 17 is a schematic diagram of determining a region of interest in an embodiment.

Detailed Description

The following description of the embodiments of the present application will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are some, but not all, of the embodiments of the present application. All other embodiments, which can be made by one of ordinary skill in the art without undue burden from the present disclosure, are within the scope of the present disclosure.

The flow diagrams depicted in the figures are merely illustrative and not necessarily all of the elements and operations/steps are included or performed in the order described. For example, some operations/steps may be further divided, combined, or partially combined, so that the order of actual execution may be changed according to actual situations.

Some embodiments of the present application are described in detail below with reference to the accompanying drawings. The following embodiments and features of the embodiments may be combined with each other without conflict.

Referring to fig. 1, fig. 1 is a flowchart of a method for determining a region of interest in an ultrasound image according to an embodiment of the present application. The method can be applied in a determination device of a region of interest in an ultrasound image for determining a region of interest of an endometrium or a binding band in the ultrasound image; for example, the method may be applied in an ultrasound imaging device, or in other terminal devices, or in a server.

Fig. 2 is a schematic block diagram of an ultrasound imaging apparatus according to an embodiment of the present application. The ultrasound imaging device 10 may include a probe 100, a transmit circuit 101, a transmit/receive select switch 102, a receive circuit 103, a beam combining circuit 104, a processor 105, and a display 106. The transmitting circuit 101 may excite the probe 100 to transmit ultrasonic waves to the target tissue; the receiving circuit 103 may receive the ultrasonic echo returned from the target tissue through the probe 100, thereby obtaining ultrasonic echo signals/data; the ultrasonic echo signals/data are subjected to beam forming processing by a beam forming circuit 104 and then sent to a processor 105. The processor 105 may process the ultrasound echo signals/data to obtain an ultrasound image or other data of the target tissue. The ultrasound images obtained by the processor 105 may be stored in the memory 107. These ultrasound images may be displayed on a display 106.

In some embodiments, peristaltic motion parameters such as peristaltic displacement or peristaltic speed of the uterus at different moments are calculated by continuously emitting ultrasonic waves to the uterus for a period of time and detecting ultrasonic echoes, thereby providing an objective assessment of the peristaltic state of the endometrium/binding band. It will be appreciated by those skilled in the art that the ultrasound imaging apparatus is also suitable for measuring peristaltic parameters of other tissues, such as intestinal tract, stomach, etc.

Specifically, the ultrasonic imaging device is used for processing the ultrasonic echo signals to obtain uterine ultrasonic images; and a step of executing a method of determining a region of interest, the region of interest being determined in the uterine ultrasound image. For example, the ultrasound imaging device comprises one or more processors 105, the one or more processors 105 working individually or jointly for performing the steps of the method of determining a region of interest in an ultrasound image.

The processor 105 is configured to execute a computer program stored in the memory 107, and when the computer program is executed, implement steps of any method for determining a region of interest in an ultrasound image provided in an embodiment of the present application.

By way of example, ultrasonic waves are transmitted to the region of interest and ultrasonic echoes are received for a period of time, ultrasonic echo signals at various positions of the region of interest can be obtained, the ultrasonic echo signals at the positions of interest in the region of interest are extracted, the ultrasonic echo signals at the positions of interest are processed, and peristaltic motion parameters at the positions of interest can be obtained. Wherein the location of interest may be at least one of the entire region of interest, a partial region of the region of interest, a plurality of partial regions of the region of interest, a point in the region of interest, or a plurality of points in the region of interest. The peristaltic movement speed or displacement of the position of interest can be calculated by comparing the ultrasonic echo signals at different moments, and the peristaltic movement parameters can be the peristaltic movement speed or displacement or other peristaltic movement parameters describing uterine peristalsis calculated by the peristaltic movement speed or displacement. The velocity or displacement at the location of interest can be calculated by block-matching or doppler methods, as well as other motion detection methods based on signal auto-correlation or cross-correlation, etc.

In some embodiments, as shown in fig. 3, the scan control module (processor 105) controls the sequence of ultrasound transmission and echo reception, and the two-dimensional image synthesis refers to the process of conventional ultrasound B-mode imaging, and may also refer to other Color imaging, PW imaging, etc. two-dimensional ultrasound images in which intima and/or bond-band morphology are visible. The display is performed by determining the region of interest that is tangential to the endometrium and/or the binding band, and then detecting and processing peristaltic waves within the region of interest.

As shown in fig. 1, the method for determining a region of interest in an ultrasound image according to the embodiment of the present application includes steps S110 to S130.

S110, acquiring an ultrasonic image of the uterus, and displaying the ultrasonic image of the uterus through a display interface of a display.

Illustratively, ultrasonic waves are sent to the uterus and ultrasonic echoes are received, ultrasonic echo signals are obtained, and ultrasonic echo signals are processed, so that an ultrasonic image of the uterus is obtained. For example, the ultrasonic imaging device excites the probe to transmit ultrasonic waves to the uterine region through the transmitting circuit, and the receiving circuit controls the probe to receive ultrasonic echoes, thereby obtaining ultrasonic echo signals. The ultrasound waves may be of any ultrasound beam type, for example: at least one of a plane wave, a divergent wave, or a focused wave.

By way of example, the ultrasound image may be any of at least one ultrasound image type of an a-type ultrasound image, a B-type ultrasound image, a C-type ultrasound image, etc., and will be described below mainly by way of example with respect to a B-type ultrasound image.

S120, determining first characteristic points of endometrium in the uterine ultrasonic image, wherein the first characteristic points comprise characteristic points positioned at the cervix uteri and characteristic points positioned at the fundus uteri.

Referring to fig. 4, the first feature points of the endometrium include feature points 1 to 6, wherein feature point 1 and/or feature point 6 are feature points located at the fundus of the uterus, and feature point 4 and/or feature point 5 are feature points located at the cervix.

In particular, the endometrium includes the anterior and posterior endometrium. Wherein, the endometrial membrane may be referred to as a first side endomembrane, and the endometrial membrane may be referred to as a second side endomembrane; alternatively, the endometrium may be referred to as a first side endometrium and the endometrium may be referred to as a second side endometrium; it will be appreciated that the first side endomembrane may be the pre-uterine membrane or the post-uterine membrane, and that the second side endomembrane and the first side endomembrane are different side endomembranes. For convenience of explanation, the embodiments of the present application mainly take the first side endometrium as the pre-uterine membrane, and the second side endometrium as the post-uterine membrane as an example. As shown in fig. 4, the curve connecting the feature point 1 to the feature point 4 is used to indicate the endometrial membrane, and the curve connecting the feature point 5 to the feature point 6 is used to indicate the endometrial membrane.

Illustratively, a first feature point of the endometrium in the ultrasound image of the uterus is determined based on image recognition, and/or a feature point selection operation by a user. For example, the first feature point may be manually determined by the user, may be automatically determined, or may be manually adjusted by the user after the automatic determination.

In some embodiments, the manner of determining the first feature point of the endometrium in the ultrasound image of the uterus based on the image recognition and the region of interest based on the first feature point may be referred to as an automatic manner, the manner of determining the first feature point of the endometrium in the ultrasound image of the uterus based on the feature point selection operation of the user, and the manner of determining the region of interest based on the first feature point may be referred to as a semi-automatic manner.

For example, the feature points may be automatically identified according to echo signals, B-image gray scale, image edge identification, artificial intelligence, or the like. For example, a first feature point of endometrium in the ultrasound image of uterus may be determined based on a machine learning model identifying the ultrasound image of uterus. The machine learning model is, for example, a deep learning model, but is not limited to this. It will be appreciated that when determining the first feature point of the endometrium in the ultrasound image of the uterus based on image recognition, the ultrasound image of the uterus may or may not be displayed by the display interface of the display. In some embodiments, the machine learning model may be trained based on the uterine ultrasound image labeled with the first feature points to enable the trained machine learning model to identify the uterine ultrasound image, determining the first feature points of the endometrium in the uterine ultrasound image.

For example, when the uterine ultrasound image is displayed through the display interface of the display, a feature point selection operation of the user may be detected, for example, a click operation of the user on the display interface is received, and the first feature point is determined. After the user performs a click operation to determine the first feature point, the determination of the first feature point may be canceled by clicking the first feature point again, or the position of the first feature point may be adjusted.

For example, after the first feature point is determined based on image recognition, the first feature point is displayed superimposed while the uterine ultrasound image is displayed, the determination of the first feature point may be canceled by clicking the first feature point again, or the position of the first feature point may also be adjusted.

In some embodiments, the first feature points of the endometrium in the ultrasound image of the uterus include feature points located on the first side of the endometrium and feature points located on the second side of the endometrium. Wherein the first side endomembrane is a endometrial membrane, the second side endomembrane is a endometrial membrane, or the first side endomembrane is a endometrial membrane, and the second side endomembrane is a endometrial membrane. As shown in fig. 4, the feature points of the inner film on the first side include feature points 1 to 4, and the feature points of the inner film on the second side include

feature points

5 and 6.

Illustratively, the characteristic points located in the first side inner membrane and the second side inner membrane each include at least a characteristic point located in the cervix and a characteristic point located in the fundus. For example, the user may trace at least 2 feature points on each side of the inner membrane. For example, of the feature points traced on both sides of the intima, at least 2 are at the fundus, 2 are at the cervix.

Illustratively, the determining the first feature point of the endometrium in the ultrasound image of the uterus based on the feature point selection operation of the user includes: and receiving the characteristic points of the endometrium from one end to the other end of the endometrium according to the trend of the endometrium by a user, and obtaining a first characteristic point of the endometrium in the ultrasonic image of the uterus. Wherein one end of the endometrium is the cervical, the other end of the endometrium is the uterine fundus, or one end of the endometrium is the uterine fundus, and the other end of the endometrium is the cervical. For example, a prompt message is output through a display interface of the display, and the prompt message may prompt the user to select a feature point from one end of the endometrium to the other end according to the trend of the endometrium.

For example, referring to fig. 4, the first feature points may be determined by marking the cervical with a number of first feature points, such as feature point 2 to feature point 4, along the anterior membrane from the position of the anterior uterine membrane, such as feature point 1; a number of first feature points, such as feature point 6, are then marked along the posterior membrane from the cervix, such as feature point 5, toward the fundus. Of course, the determination order of the first feature points may be reversed from that shown in fig. 4, for example; alternatively, the order of determination of the first feature points may be determined autonomously by the user, e.g. the first feature point at the beginning and the first feature point at the end may be at the cervix, and the first feature point at the turn may be at the fundus.

The number of the first feature point of the endometrium in the ultrasound image of the uterus may or may not be displayed.

And S130, automatically connecting the first characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus according to the trend of the endometrium to form an endometrium boundary line of the endometrium.

In some embodiments, according to the trend of the endometrium, automatically connecting the characteristic points of the cervix including the first side endometrium and the characteristic points of the fundus to form a first side endometrium boundary line; and automatically connecting the characteristic points of the cervix including the second side endometrium and the characteristic points of the fundus according to the trend of the endometrium to form a second side endometrium boundary line. For example, automatically connecting feature point 1 to feature point 4 of the endometrium generates a first lateral endometrium boundary line, for example called anterior membrane boundary line; automatically connecting the characteristic point 5 to the characteristic point 6 of the endometrium forms a second lateral endometrium border line, for example called the posterior border line.

For example, when the first feature points are automatically connected, the first feature points may be connected in a straight line or in an arc line, which is not limited to this, and may be connected in a broken line, for example.

Illustratively, the first characteristic points including the characteristic points of the cervix and the characteristic points of the fundus are automatically connected, and an endometrium boundary line forming the endometrium may be a folded line, a straight line, a regular or irregular curve, or the like, without limitation.

In some embodiments, the first feature points are automatically connected one by one from the feature point at one end of the endometrium to the feature point at the other end of the endometrium according to the trend of the endometrium, so as to form an endometrium boundary line of the endometrium. Wherein one end of the endometrium is the cervical, the other end of the endometrium is the uterine fundus, or one end of the endometrium is the uterine fundus, and the other end of the endometrium is the cervical. Referring to fig. 4, when the connecting feature points form an intima boundary line, the connecting feature points may be connected from feature point 1 to feature point 4 via feature point 2 and feature point 3, and from feature point 5 to feature point 6.

Illustratively, according to the trend of the endometrium, automatically connecting the characteristic points from one end of the first side endometrium to the characteristic points at the other end one by one to form a first side endometrium boundary line; and automatically connecting the characteristic points positioned at one end of the second side endometrium to the characteristic points positioned at the other end one by one according to the trend of the endometrium to form a second side endometrium boundary line. For example, the connection direction of the feature points is the same or opposite to that of the second side inner film boundary line when the first side inner film boundary line is formed.

Illustratively, the method further comprises: identifying the area where the endometrium is located, and determining the trend of the endometrium according to the area where the endometrium is located. For example, key structural features in the ultrasound image of the uterus can be automatically identified by intelligent means such as artificial intelligence, image identification and the like, so that the area where the endometrium is located is automatically determined in the ultrasound image of the uterus. The identified area of the endometrium may include at least one of a rectangular, circular, fan-shaped, line segment, or dot shape. For example, the trend of the endometrium may be determined from the boundaries of the area in which the endometrium is located.

Illustratively, the method further comprises: identifying the lateral endometrium of the endometrium, and determining the trend of the endometrium according to the trend of the lateral endometrium of the endometrium. For example, the lateral endometrium of the endometrium, such as the pre-and post-uterine membranes, can be automatically identified by intelligent means such as artificial intelligence, image recognition, etc.; determining the trend of the endometrium from the identified trend of the lateral endometrium.

Illustratively, at least a portion of the line segment of the boundary line of the endometrium formed in step S130 is parallel to the orientation of the endometrium, such as a line between at least two adjacent first feature points is parallel to the orientation of the endometrium.

In some embodiments, after the endometrium boundary line of the endometrium is formed in step S130, the number and/or the position of the first feature points in the uterine ultrasound image may be adjusted based on the feature point selection operation of the user, so that the user can adjust the position of the feature points in time, so that the region of interest obtained later is more accurate.

In some embodiments, the first feature points are automatically connected one by one according to a shortest path according to the trend of the endometrium, so as to form an endometrium boundary line of the endometrium.

Illustratively, a starting point is selected from the first feature points; and connecting the starting points one by one in a counter-clockwise/clockwise direction and in a shortest path to form an endometrium boundary line of the endometrium.

For example, the starting point is a feature point located at the cervix uteri or a feature point at the fundus among the third feature points.

And S140, determining at least the area between the endometrium boundary lines in the uterine ultrasound image as the region of interest.

In some embodiments, at least a region between the first side intima boundary line and the second side intima boundary line in the uterine ultrasound image may be determined as the region of interest. Referring to fig. 4, at least the front film boundary lines corresponding to the feature points 1 to 4 are determined, and the region between the rear film boundary lines corresponding to the feature points 5 to 6 is the region of interest.

The two ends of the front membrane boundary line and the rear membrane boundary line are connected, and the obtained region is the region of interest, which is not limited to this.

By determining a first characteristic point of endometrium in an ultrasonic image of uterus and automatically connecting the first characteristic point according to the trend of the endometrium, an endometrium boundary line of the endometrium is formed, wherein the endometrium boundary line can be used as a boundary of an interested region, so that the boundaries of the interested region on two sides of the endometrium can be determined according to the determined endometrium boundary line; meanwhile, through the characteristic points positioned at the cervix and the characteristic points positioned at the cervix, the endpoints of the boundary line of the endometrium at the cervix and the cervix can be limited; therefore, the region of interest determined by the embodiment of the application is more accurate, interference caused by movement outside the region of interest on observation and analysis of peristalsis can be eliminated, and the observation range is better locked in the endometrial or binding band area only.

In other embodiments, the first feature point of the endometrium in the ultrasound image of the uterus comprises a feature point located on the first side endometrium. For example, in determining the first characteristic point of the endometrium, it is possible to determine the characteristic point of the endometrium on one side. Referring to fig. 5, feature points 1 to 4 of the first side inner film are determined.

Illustratively, said automatically connecting said first characteristic point comprising characteristic points of said cervix and characteristic points of said fundus according to a trend of said endometrium, forming an endometrium border line of said endometrium, comprises: according to the trend of the endometrium, automatically connecting the characteristic points of the cervix and the characteristic points of the fundus of the uterus one by one to form a first side endometrium boundary line; and generating a second side inner membrane boundary line at a position close to the second side inner membrane according to the first side inner membrane boundary line.

Illustratively, according to the trend of the endometrium, the characteristic points at one end of the first side endometrium are automatically connected one by one to the characteristic points at the other end to form a first side endometrium boundary line.

Referring to fig. 5, according to the trend of the endometrium, automatically connecting the feature point 1 to the feature point 4 to form an anterior membrane boundary line; a rear film boundary line may be generated from the front film boundary line.

The shape of the second side inner film boundary line generated according to the first side inner film boundary line is the same as the shape of the first side inner film boundary line, or may be different, for example, the length of the second side inner film boundary line generated is not equal to the first side inner film boundary line; illustratively, the second side inner membrane boundary line generated from the first side inner membrane boundary line is parallel to the first side inner membrane boundary line, but is not limited thereto.

For example, referring to fig. 5, the generating a second side inner membrane boundary line at a position close to the second side inner membrane according to the first side inner membrane boundary line includes: copying the first side inner membrane boundary line and moving a first preset distance to the direction of the second side inner membrane to obtain the second side inner membrane boundary line. For example, as shown in fig. 5, the direction in which the reproduced first side inner film boundary line moves may be a vertical direction; in other embodiments, the direction in which the replicated first side inner film boundary line moves may be the normal direction of the first side inner film boundary line at a position, i.e., the perpendicular direction of the tangent line; for example, the direction in which the copied first-side intima boundary line moves is the normal direction of the first-side intima boundary line at a characteristic point of the first-side intima (such as a characteristic point of the cervix or a characteristic point of the fundus).

Illustratively, the first feature point of endometrium in the ultrasound image of uterus further includes a feature point of endometrium located at the second side, referring to fig. 6, the first feature point further includes a feature point of endometrium 6. For example, the generating a second side inner membrane boundary line at a position close to the second side inner membrane according to the first side inner membrane boundary line includes: copying the first side inner membrane boundary line and moving to coincide with at least one characteristic point of the second side inner membrane to obtain the second side inner membrane boundary line. For example, the direction in which the replicated first side inner membrane boundary line moves may be a vertical direction; in other embodiments, the direction in which the replicated first side inner membrane boundary line moves may be a normal direction to the first side inner membrane boundary line at a location. Of course, the direction in which the copied first side inner membrane boundary line moves is determined based on, for example, the fundus feature point of the first side inner membrane and the fundus feature point of the second side inner membrane, or the direction in which the copied first side inner membrane boundary line moves is determined based on the cervical feature point of the first side inner membrane and the cervical feature point of the second side inner membrane.

In other embodiments, the first feature point of endometrium in the ultrasound image of uterus comprises a feature point located on the first side endometrium; the first characteristic points of the endometrium in the uterine ultrasonic image further comprise characteristic points positioned on the second side endometrium; the characteristic points of the second side inner film comprise points which are close to the second side inner film according to the vertical line direction of the characteristic points of the first side inner film and have a second preset distance from the characteristic points of the first side inner film, or the characteristic points of the second side inner film comprise points which are close to the second side inner film and have a third preset distance from the characteristic points of the first side inner film according to the vertical line direction of the boundary line generated by the characteristic points of the first side inner film. The second distance and the third distance may be equal or different.

Illustratively, the determining a first feature point of endometrium in the ultrasound image of uterus comprises: determining a characteristic point of a first side endometrium of the endometrium in the uterine ultrasound image; and taking a point which is close to the second side inner film in the vertical direction according to the characteristic point of the first side inner film and has a second preset distance from the characteristic point of the first side inner film as the characteristic point of the second side inner film. The mode of determining the characteristic points of the inner membrane at the second side through the characteristic points of the inner membrane at the first side and the vertical direction (the vertical direction) is convenient and quick.

Illustratively, the determining a first feature point of endometrium in the ultrasound image of uterus comprises: determining a characteristic point of a first side endometrium of the endometrium in the uterine ultrasound image; and taking a point which is close to the second side inner film in the vertical line direction of the boundary line generated according to the characteristic point of the first side inner film and has a third preset distance from the characteristic point of the first side inner film as the characteristic point of the second side inner film. The characteristic points of the second side inner film are determined more accurately by the curve generated by the characteristic points of the first side inner film and the mode of determining the characteristic points of the second side inner film in the normal direction of each characteristic point on the curve.

Referring to fig. 7, determining the characteristic points 1 'to 4' of the second side inner film at a position close to the second side inner film according to the characteristic points 1 to 4 of the first side inner film; alternatively, the determined characteristic points of the second side inner film may be less than or equal to the characteristic points of the first side inner film.

Illustratively, according to the trend of the endometrium, automatically connecting the characteristic points of the cervix and the characteristic points of the fundus of the uterus, which are positioned on the first side endometrium, to form a first side endometrium boundary line of the endometrium; and determining the characteristic point of the second side inner membrane at a position close to the second side inner membrane according to the perpendicular direction of the first characteristic point of the first side inner membrane boundary line and the two preset distances.

Referring to fig. 7, the user traces at least 2 feature points on one side of the endometrium (at least 1 point on each of the cervical and fundus), the system generates a single-side curve according to the feature points, and obtains the feature points on the other side according to the perpendicular line segment (corresponding to the second preset distance) of the tangent line of the feature points on the single-side curve. For example, the second preset distances corresponding to the different first feature points may be equal or unequal, for example, the second preset distance corresponding to the feature point at the cervix may be less than or equal to the second preset distance corresponding to the feature point at the fundus, for example, the second preset distances corresponding to the feature points of the first endometrium may be arranged in an equi-differential manner, an equi-ratio manner, or follow other specific rules. In some embodiments, the second preset distance may be set or adjusted by the user himself.

Illustratively, said automatically connecting said first characteristic point comprising characteristic points of said cervix and characteristic points of said fundus according to a trend of said endometrium, forming an endometrium border line of said endometrium, comprises: according to the trend of the endometrium, automatically connecting characteristic points of a cervix and characteristic points of a fundus positioned on the first side endometrium to form a first side endometrium boundary line of the endometrium; according to the trend of the endometrium, automatically connecting the characteristic points of the cervix and the characteristic points of the fundus of the uterus which are positioned on the second side endometrium to form a second side endometrium boundary line of the endometrium.

As shown in fig. 7, the user traces several points along the edge of the endometrium, the initial point is a characteristic point 1 of the position of the endometrium, several characteristic points 1 to 4 are marked along the direction from the endometrium to the cervix, and the characteristic points 1 to 4 are automatically connected to generate an anterior membrane boundary line; the vertical line direction of the tangent line of the anterior membrane boundary line at each position from the characteristic point 1 to the characteristic point 4 is found, and corresponding specific lengths, such as vertical line segments with the lengths of 15, 26, 37 and 48 in sequence, are automatically generated in the posterior membrane direction, the tail end of the vertical line segment can be determined as the characteristic point of the posterior membrane of the uterus, such as the characteristic point 1 'to the characteristic point 4', and the posterior membrane boundary line can be generated by automatically connecting the characteristic point 1 'to the characteristic point 4'.

Illustratively, forming the feature points of the second-side intima boundary line includes: and the first characteristic points are located at the characteristic points of the second side inner film, and the points which are close to the second side inner film according to the vertical line direction of the characteristic points of the first side inner film and have the distance of a second preset distance from the characteristic points of the first side inner film. For example, the second-side inner film boundary line may be formed according to the feature points of the second-side inner film determined based on the image recognition and/or the feature point selection operation of the user, and the feature points of the second-side inner film determined according to the feature points of the first-side inner film, so that the second-side inner film boundary may be more accurate, or the user may determine fewer feature points, saving the workload.

In some embodiments, the region of interest further comprises: generating a uterine fundus area according to the characteristic points positioned at the uterine fundus, and/or generating a uterine neck area according to the characteristic points positioned at the uterine neck. Referring to fig. 8, the region between the boundary lines of the inner membrane may be referred to as a region a, the region of the uterine fundus generated from the feature points located at the uterine fundus may be referred to as a region B, and the region of the cervix generated from the feature points located at the cervix may be referred to as a region C; the region of interest may be determined from the closed loop region formed by region a, region B, region C, such as the intersection. The region of interest may more fully represent uterine peristalsis.

Illustratively, the fundus and cervical regions may include one or more of the following shapes: circular, elliptical, rectangular, polygonal, of course not limited thereto, and may be set by a user, for example.

Illustratively, when the uterine ultrasound image is a longitudinal section ultrasound image, the fundus region is a circular region and the cervical region is a rectangular region. The region of interest determined in the longitudinal section ultrasound image can be made more accurate.

Illustratively, when the uterine ultrasound image is a cross-section ultrasound image, the fundus region and the cervical region are both circular regions. The region of interest determined in cross-section ultrasound images can be made more accurate.

Illustratively, the circular region is tangent to the intima boundary line (e.g., tangent to the anterior membrane boundary line) at least at one location, and/or at least one vertex of the rectangular region is located on the intima boundary line.

Illustratively, the generating the uterine fundus area according to the characteristic points located at the uterine fundus and/or generating the uterine cervix area according to the characteristic points located at the uterine cervix includes: generating the uterine fundus area according to the boundary line end point positioned at the uterine fundus on the endometrium boundary line in the uterine ultrasound image; and generating the cervical region according to the boundary line end point of the endometrium boundary line positioned at the cervical in the uterine ultrasonic image. For example, referring to fig. 8, a circular area B may be automatically generated according to the marked anterior uterine membrane feature points 1 and the marked posterior uterine membrane feature points 6 as an area of the uterine floor, where the circular area may be a diameter of a line connecting the anterior uterine membrane feature points 1 and the marked posterior uterine membrane feature points 6, or may be tangential to an anterior uterine membrane boundary line and a posterior uterine membrane boundary line; the anterior cervical membrane characteristic points 4 and the posterior cervical membrane characteristic points 5 are connected, and a rectangular area C is formed by extending to the cervical part along the tangential direction of the anterior cervical membrane boundary line and/or the posterior membrane boundary line corresponding to the anterior cervical membrane characteristic points 4 and the posterior cervical membrane characteristic points 5 as a cervical area. Of course, the present invention is not limited to this, and for example, the anterior cervical membrane feature point 4 and the posterior cervical membrane feature point 5 are directly connected as boundaries of the region of interest at the cervix.

For example, the size, location, etc. of the fundus, cervical regions may also be set by the user. For example, the radius, position, shape of the circular region B may be adjusted, and the size, orientation, shape of the rectangular region C; optionally, feature points on the curve also allow for reediting.

For example, the identification of each region may or may not be displayed, and each region may be displayed in a combined manner or may be displayed separately; the area a, the area B, and the area C may be generated only one of A, B, C, or each of two, or three.

Illustratively, the identification of feature points, regions is not limited to color, shape, number, text, speech, brightness, transparency, map, etc. identifications.

According to the method for determining the region of interest in the ultrasonic image, which is provided by the embodiment of the application, the first characteristic point of the endometrium in the ultrasonic image of the uterus is determined, and the first characteristic point is automatically connected according to the trend of the endometrium to form the endometrium boundary line of the endometrium, so that the boundary of the region of interest at two sides of the endometrium can be determined according to the determined endometrium boundary line; meanwhile, the first characteristic points comprise characteristic points positioned at the cervix uteri and characteristic points positioned at the fundus, and can limit the endpoints of the boundary line of the inner membrane at the cervix uteri and the fundus; the method can more accurately identify the region of interest in the uterine ultrasound image, eliminate interference of movement outside the region of interest on observation and analysis of peristalsis, and better lock the observation range in the endometrial or binding band region only.

By way of example, compared with the method for determining the shape of the region of interest by only manually tracing the shape of the inner membrane/binding band, the method for determining the shape of the region of interest can save the workload of a user and is higher in efficiency; compared with the existing automatic endometrial recognition technology, such as an artificial intelligence direct recognition mode of the region of interest, the accuracy and stability are higher.

Referring to fig. 9 in combination with the foregoing embodiments, fig. 9 is a flowchart illustrating a method for determining a region of interest in an ultrasound image according to another embodiment of the present application.

As shown in fig. 9, the method of the embodiment of the present application includes steps S210 to S240.

S210, acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

s220, determining first characteristic points of endometrium in the uterine ultrasonic image, wherein the first characteristic points comprise characteristic points positioned at cervix uteri and characteristic points positioned at fundus uteri;

and S230, automatically connecting the first characteristic points one by one from the characteristic points at one end of the endometrium to the characteristic points at the other end of the endometrium according to the trend of the endometrium to form an endometrium boundary line of the endometrium.

Wherein one end of the endometrium is the cervical, the other end of the endometrium is the uterine fundus, or one end of the endometrium is the uterine fundus, and the other end of the endometrium is the cervical;

S240, determining at least the area between the endometrium boundary lines in the uterine ultrasound image as the region of interest.

Optionally, the first characteristic point of endometrium in the ultrasound image of uterus comprises a characteristic point of endometrium on a first side and a characteristic point of endometrium on a second side, wherein the first side endometrium is a endometrial membrane, the second side endometrium is a endometrial membrane, or the first side endometrium is a endometrial membrane, and the second side endometrium is a endometrial membrane. According to the trend of the endometrium, automatically connecting the first characteristic points one by one from the characteristic points at one end of the endometrium to the characteristic points at the other end of the endometrium to form an endometrium boundary line of the endometrium, and comprising the following steps: automatically connecting the characteristic points at one end of the first side endometrium to the characteristic points at the other end one by one according to the trend of the endometrium to form a first side endometrium boundary line; automatically connecting the characteristic points positioned at one end of the second side endometrium to the characteristic points positioned at the other end one by one according to the trend of the endometrium to form a second side endometrium boundary line; the determining that at least the area between the endometrium boundary lines in the uterine ultrasound image is the region of interest comprises: determining a region between at least the first side intima boundary line and the second side intima boundary line in the uterine ultrasound image as the region of interest.

Optionally, the first characteristic point of endometrium in the uterine ultrasonic image comprises a characteristic point of endometrium on a first side, and the first side endometrium is an endometrial or postuterine membrane; according to the trend of the endometrium, automatically connecting the first characteristic points one by one from the characteristic points at one end of the endometrium to the characteristic points at the other end of the endometrium to form an endometrium boundary line of the endometrium, and comprising the following steps: according to the trend of the endometrium, automatically connecting the characteristic points positioned at one end of the first side endometrium to the characteristic points positioned at the other end one by one to form a first side endometrium boundary line; and generating a second side inner film boundary line at a position close to a second side inner film according to the first side inner film boundary line, wherein the second side inner film and the first side inner film are inner films on different sides.

Optionally, the generating a second side inner membrane boundary line at a position close to the second side inner membrane according to the first side inner membrane boundary line includes: copying the first side inner membrane boundary line and moving a first preset distance to the direction of the second side inner membrane to obtain the second side inner membrane boundary line.

Optionally, the first characteristic points of endometrium in the ultrasound image of uterus further comprise characteristic points of endometrium at the second side; the generating a second side inner membrane boundary line at a position close to the second side inner membrane according to the first side inner membrane boundary line comprises: copying the first side inner membrane boundary line and moving to coincide with at least one characteristic point of the second side inner membrane to obtain the second side inner membrane boundary line.

Optionally, the determining the first characteristic point of endometrium in the ultrasound image of uterus includes: determining a characteristic point of a first side endometrium of the endometrium in the uterine ultrasound image; and taking a point which is close to the second side inner film in the vertical direction according to the characteristic point of the first side inner film and is at a second preset distance from the characteristic point of the first side inner film as the characteristic point of the second side inner film, or taking a point which is close to the second side inner film in the vertical direction according to the boundary line generated by the characteristic point of the first side inner film and is at a third preset distance from the characteristic point of the first side inner film as the characteristic point of the second side inner film, wherein the vertical line passes through the characteristic point of the first side inner film.

Optionally, the region of interest further includes: generating a uterine fundus area according to the characteristic points positioned at the uterine fundus, and/or generating a uterine neck area according to the characteristic points positioned at the uterine neck.

Optionally, when the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus area is a circular area, and the cervical area is a rectangular area; optionally, when the uterine ultrasound image is a cross-section ultrasound image, the uterine fundus area and the cervical area are both circular areas.

Optionally, the circular area is tangent to the intima boundary line at least at one point, and/or at least one vertex of the rectangular area is located on the intima boundary line.

Optionally, the generating the uterine fundus area according to the characteristic points located at the uterine fundus and/or generating the uterine neck area according to the characteristic points located at the uterine neck includes: generating the uterine fundus area according to the boundary line end point positioned at the uterine fundus on the endometrium boundary line in the uterine ultrasound image; and generating the cervical region according to the boundary line end point of the endometrium boundary line positioned at the cervical in the uterine ultrasonic image.

Optionally, the determining the first characteristic point of endometrium in the ultrasound image of uterus includes: and determining a first characteristic point of endometrium in the uterine ultrasound image based on image identification and/or characteristic point selection operation of a user.

Optionally, the determining the first feature point of the endometrium in the ultrasound image of the uterus based on the feature point selection operation of the user includes: and receiving the characteristic points of the endometrium from one end to the other end of the endometrium according to the trend of the endometrium by a user, and obtaining a first characteristic point of the endometrium in the ultrasonic image of the uterus.

Optionally, the method further comprises: identifying the area where the endometrium is located, and determining the trend of the endometrium according to the area where the endometrium is located; or identifying the lateral endometrium of the endometrium, and determining the trend of the endometrium according to the trend of the lateral endometrium of the endometrium.

Referring to fig. 10 in combination with the foregoing embodiments, fig. 10 is a flowchart illustrating a method for determining a region of interest in an ultrasound image according to another embodiment of the present application.

As shown in fig. 10, the method of the embodiment of the present application includes steps S310 to S350.

S310, acquiring a uterine ultrasound image, and displaying the uterine ultrasound image through a display interface of a display;

s320, determining first characteristic points of endometrium in the uterine ultrasonic image, wherein the first characteristic points comprise characteristic points positioned at cervix uteri and characteristic points positioned at fundus uteri;

s330, according to the trend of the endometrium, automatically connecting the characteristic points of the endometrium on the first side one by one from the characteristic points on one end to the characteristic points on the other end to form a first side endometrium boundary line;

and S340, automatically connecting the characteristic points of the second side endometrium of the endometrium one by one according to the trend of the endometrium from the characteristic points of the other end to the characteristic points of one end to form a second side endometrium boundary line.

Wherein the first side endomembrane is a endometrial membrane, the second side endomembrane is a endometrial membrane, or the first side endomembrane is a endometrial membrane, and the second side endomembrane is a endometrial membrane.

S350, determining at least the area between the first side inner membrane boundary line and the second side inner membrane boundary line in the uterine ultrasound image as the region of interest.

Wherein the feature points forming the second side intima boundary line include: and the first characteristic points are located at the characteristic points of the second side inner film, and the points which are close to the second side inner film according to the vertical line direction of the characteristic points of the first side inner film and have the distance of a second preset distance from the characteristic points of the first side inner film.

Referring to fig. 11 in combination with the foregoing embodiments, fig. 11 is a flowchart illustrating a method for determining a region of interest in an ultrasound image according to still another embodiment of the present application.

As shown in fig. 11, the method of the embodiment of the present application includes steps S410 to S450.

S410, acquiring an ultrasonic image of the uterus, and displaying the ultrasonic image of the uterus through a display interface of a display.

S420, determining second characteristic points in the uterine cavity of the endometrium in the uterine ultrasonic image, wherein the second characteristic points comprise characteristic points positioned at the cervix and characteristic points positioned at the uterine fundus.

Referring to fig. 12, the second feature points in the uterine cavity include feature points 1 to 4, wherein feature point 1 is a feature point located at the fundus of the uterus and feature point 4 is a feature point located at the cervix. For example, a second feature point of a uterine cavity midline in the uterine ultrasound image is determined.

Illustratively, a second feature point in the uterine cavity in the uterine ultrasound image is determined based on image recognition, and/or a feature point selection operation by the user. For example, the second feature point may be manually determined by the user, may be automatically determined, or may be manually adjusted by the user after the automatic determination, and the foregoing embodiment of determining the first feature point may be referred to, which is not described herein.

Illustratively, the receiving user selects and operates from the characteristic points from one end to the other end of the uterine cavity according to the trend of the endometrium, so as to obtain a second characteristic point in the uterine cavity of the endometrium in the uterine ultrasonic image. One end of the uterine cavity is the cervical, the other end of the uterine cavity is the uterine bottom, or one end of the uterine cavity is the uterine bottom, and the other end of the uterine cavity is the cervical.

The number of the second feature point in the uterine cavity may or may not be displayed.

And S430, automatically connecting the second characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus according to the trend of the endometrium to form a uterine cavity line of the endometrium.

Referring to fig. 12, the characteristic points 1 to 4 in the uterine cavity are automatically connected to form a uterine cavity line of the endometrium.

Illustratively, according to the trend of the endometrium, the second characteristic points are automatically connected one by one from the characteristic point at one end of the uterine cavity to the characteristic point at the other end of the uterine cavity, so as to form a uterine cavity line of the endometrium. One end of the uterine cavity is the cervical, the other end of the uterine cavity is the uterine bottom, or one end of the uterine cavity is the uterine bottom, and the other end of the uterine cavity is the cervical.

The second feature points may be connected automatically by a straight line connection or an arc connection, which is not limited to this, but may be a broken line connection.

For example, the uterine cavity line formed by automatically connecting the second feature points may be a folded line segment, a straight line, or a regular or irregular curve, which is not limited thereto.

Illustratively, the method further comprises: identifying the area where the endometrium is located, and determining the trend of the endometrium according to the area where the endometrium is located.

Illustratively, the method further comprises: identifying the lateral endometrium of the endometrium, and determining the trend of the endometrium according to the trend of the lateral endometrium of the endometrium.

Illustratively, the intrauterine line formed in step S430 is at least partially parallel to the endometrial direction, such as a line between at least two adjacent second feature points is parallel to the endometrial direction.

S440, generating an anterior membrane boundary line and a posterior membrane boundary line based on the uterine cavity line.

The uterine cavity line is formed by automatically connecting said second characteristic points comprising characteristic points of said cervix and characteristic points of said fundus according to the trend of said endometrium, so that the shape of the uterine cavity line is substantially the same as the shape of the endometrium and/or the endometrium, and the anterior and posterior membrane boundary lines can be generated by, for example, translating the uterine cavity line. Wherein the anterior membrane border line is used to indicate the boundary of the endometrium and the posterior membrane border line is used to indicate the boundary of the endometrium.

In some embodiments, the generating anterior and posterior membrane boundary lines based on the uterine cavity line comprises: moving the uterine cavity line to a first side endometrium position to obtain a first side endometrium boundary line, wherein the first side endometrium is the pre-uterine membrane or the post-uterine membrane; and copying the first side inner membrane boundary line and moving to the position of the second side inner membrane to obtain a second side inner membrane boundary line, wherein the second side inner membrane and the first side inner membrane are inner membranes on different sides. Referring to fig. 12, the uterine cavity lines indicated by the feature points 1 to 4 are moved upward to obtain a anterior membrane boundary line; the front film boundary line is moved downward, and the rear film boundary line can be obtained.

In other embodiments, the generating anterior and posterior membrane boundary lines based on the uterine cavity line comprises: copying the uterine cavity lines to obtain two uterine cavity lines; moving one of the uterine cavity lines to the position of the endometrium to obtain the anterior membrane boundary line; and moving the other of the two uterine cavity lines to the direction of the endometrium to obtain the posterior membrane boundary line. Referring to fig. 12, the uterine cavity lines indicated by the feature points 1 to 4 are moved upward to obtain a anterior membrane boundary line; the posterior membrane boundary line can be obtained by moving the uterine cavity line downwards.

For example, when moving the uterine cavity line or moving the first lateral intima borderline generated according to the uterine cavity line, the moving direction may be a vertical direction, or may be a normal direction of the uterine cavity line or the first lateral intima borderline at a position, i.e. a vertical direction of a tangent line, for example, a normal direction of the uterine cavity line at a second characteristic point (such as a characteristic point of a cervix or a characteristic point of a fundus). Of course, also without limitation, the direction of movement may be determined autonomously by the user, or based on the second characteristic point and the first characteristic point of the endometrium in the ultrasound image of the uterus, for example. For example, the movement direction is determined from the second feature point of the fundus and the first feature point of the fundus.

For example, when moving the uterine cavity line or the first lateral intima borderline generated from the uterine cavity line, the distance moved may also be a preset distance, or the distance moved may be adjusted according to the user's operation.

Illustratively, the method further comprises determining a first characteristic point of the endometrium in the ultrasound image of the uterus, such as a first characteristic point of the pre-and/or post-uterine membrane; moving to a position coincident with the first feature point of at least one of the anterior or posterior uterine membranes while moving the lumen line to create the first or second lateral endomembrane boundary line; and moving to a position coinciding with the first characteristic point of the at least one pre-or post-uterine membrane when moving the first side endomembrane border line to obtain the second side endomembrane border line.

In some other embodiments, the generating anterior and posterior membrane boundary lines based on the uterine cavity line comprises: determining feature points of the endometrium and feature points of the endometrium based on the intrauterine line and the second feature points; the anterior membrane boundary line is determined from the characteristic points of the endometrium, and the posterior membrane boundary line is determined from the characteristic points of the endometrium.

For example, a point which is close to the endometrium in the normal direction or the perpendicular direction of the uterine cavity line and which is a third preset distance from the second characteristic point is taken as the characteristic point of the endometrium.

Referring to fig. 12, from feature point 1 to feature point 4 of the uterine cavity, feature point 1 'to feature point 4' of the endometrial membrane are determined at a position close to the endometrial membrane; alternatively, the determined characteristic points of the endometrium may be less than or equal to the second characteristic points.

For example, a point which is close to the endometrium in the normal direction or the vertical direction of the curve corresponding to the uterine cavity line and has a distance of a fourth preset distance from the second characteristic point is taken as the characteristic point of the endometrium. For example, according to the trend of the endometrium, characteristic points of the endometrium are automatically connected to form the boundary line of the endometrium. It should be noted that, forming the anterior membrane boundary line may further include determining the first feature point of the endometrium based on image recognition and/or a feature point selection operation by the user, so that the second-side endometrium boundary may be more accurate.

Referring to fig. 12, from feature point 1 to feature point 4 of the uterine cavity, feature point 1 "to feature point 4" of the uterine membrane are determined at a position near the uterine membrane; alternatively, the determined characteristic point of the endometrium may be less than or equal to the second characteristic point. For example, according to the trend of the endometrium, characteristic points of the endometrium are automatically connected to form the posterior border line. It should be noted that, forming the posterior membrane boundary line may further include determining the first feature point of the endometrium based on image recognition and/or a feature point selection operation by the user, so that the second-side endometrium boundary may be more accurate.

For example, the third preset distance and the fourth preset distance corresponding to the second different feature points may be equal or unequal; for example, the third preset distance corresponding to the characteristic point at the cervix uteri is smaller than or equal to the third preset distance corresponding to the characteristic point at the fundus uteri; for example, the third preset distance corresponding to the second feature point is arranged in an equi-differential manner, arranged in an equi-ratio manner or conforms to other specific rules. In some embodiments, the third preset distance and the fourth preset distance may be set or adjusted by the user.

S450, determining at least the area between the anterior membrane boundary line and the posterior membrane boundary line in the uterine ultrasound image as the region of interest.

Referring to fig. 12, at least the front film boundary lines corresponding to the feature points 1 'to 4' are determined, and the region between the rear film boundary lines corresponding to the feature points 1 "to 4" is the region of interest.

In some embodiments, the region of interest further comprises: a fundus region is created at an end of the anterior and posterior membrane boundary lines near the fundus and/or a cervical region is created at an end near the cervix. Reference may be made specifically to the description of the fundus and cervical regions in the foregoing embodiments, and no further description is given here.

Illustratively, when the uterine ultrasound image is a longitudinal section ultrasound image, the fundus region is a circular region and the cervical region is a rectangular region; and/or when the uterine ultrasound image is a cross-section ultrasound image, the uterine fundus area and the cervical area are both circular areas.

Illustratively, the circular region is tangent to the front film boundary line or the rear film boundary line at least at one point, and/or at least one vertex of the rectangular region is located on the front film boundary line or the rear film boundary line.

Illustratively, the generating the uterine fundus area according to the characteristic points located at the uterine fundus and/or generating the uterine cervix area according to the characteristic points located at the uterine cervix includes: generating the uterine fundus area according to a boundary line endpoint of the anterior membrane boundary line positioned at the uterine fundus and a boundary endpoint of the posterior membrane boundary line positioned at the uterine fundus in the uterine ultrasound image; and/or generating the uterine fundus area according to the boundary line end point of the anterior membrane boundary line positioned at the cervix and the boundary line end point of the posterior membrane boundary line positioned at the cervix in the uterine ultrasound image.

According to the method for determining the region of interest in the ultrasonic image, the second characteristic points in the uterine cavity of the endometrium in the ultrasonic image of the uterus are determined, and according to the trend of the endometrium, the second characteristic points comprising the characteristic points of the cervix and the characteristic points of the fundus are automatically connected to form a uterine cavity line of the endometrium; generating a front membrane boundary line and a rear membrane boundary line according to the uterine cavity line, and determining boundaries of the region of interest on two sides of the inner membrane according to the region between the front membrane boundary line and the rear membrane boundary line; meanwhile, the second characteristic points comprise characteristic points positioned at the cervix uteri and characteristic points positioned at the fundus, and can limit the endpoints of the boundary line of the inner membrane at the cervix uteri and the fundus; the method can more accurately identify the region of interest in the uterine ultrasound image, eliminate interference of movement outside the region of interest on observation and analysis of peristalsis, and better lock the observation range in the endometrial or binding band region only.

In some embodiments, the region of interest may not cover the entire endometrium, e.g., only a single-sided endometrium region need be covered. Illustratively, the method includes: acquiring a uterine ultrasound image and displaying the uterine ultrasound image through a display interface of a display; determining a second feature point in the uterine cavity of the endometrium in the uterine ultrasound image, wherein the second feature point comprises a feature point positioned at the cervix and a feature point positioned at the fundus; according to the trend of the endometrium, automatically connecting the second characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus to form a uterine cavity line of the endometrium; generating a anterior membrane boundary line and/or a posterior membrane boundary line based on the uterine cavity line; and determining the region between any two of at least the anterior membrane boundary line, the posterior membrane boundary line and the uterine cavity line in the uterine ultrasound image as the region of interest.

For example, a anterior membrane boundary line is generated based on a uterine cavity line, the region between the anterior membrane boundary line and the uterine cavity line being the region of interest. The anterior membrane boundary line can be obtained by copying and moving the uterine cavity line, or can be obtained by determining the first characteristic point according to the perpendicular line of the uterine cavity line and automatically connecting the first characteristic point.

In some embodiments, referring to fig. 13, a first feature point on one side of the endometrium in the ultrasound image of the uterus, such as feature point 1 to feature point 4 of the endometrium; automatically connecting the first feature points according to the trend of the endometrium to form an endometrium boundary line (a curve indicated by feature points 1 to 4, which may be referred to as a anterior membrane boundary line) on one side of the endometrium; according to the boundary line of the endometrium on one side of the endometrium, a uterine cavity line, such as a curve indicated by the characteristic points 1 'to 4', can be obtained; and determining a region between an endometrium boundary line on at least one endometrium side and the uterine cavity line in the uterine ultrasonic image as the region of interest. The uterine cavity line may be obtained by copying and moving the endometrium boundary line on the endometrium side, or by determining the second characteristic point (such as characteristic point 1 'to characteristic point 4' in fig. 13) of the uterine cavity from the perpendicular line of the endometrium boundary line on the endometrium side, and automatically connecting the second characteristic point.

For example, referring to fig. 14, the region of interest may further include creating a fundus region at an end of the anterior membrane boundary line and/or the posterior membrane boundary line near the fundus, and/or creating a cervical region at an end near the cervix. The feature points p1 and p2 are first feature points of the endometrial or endometrial based on image recognition and/or feature point selection operation of a user. The fundus area, the cervical area may be generated based on a boundary line of the anterior membrane formed from the uterine cavity line and the first feature point of the posterior membrane; or may generate a fundus and/or cervical region based on a posterior membrane boundary line formed from a lumen line and the first characteristic point of the anterior membrane.

In some embodiments, the region of interest comprises an intima/bond band region on one side of the uterus. Illustratively, the method includes: acquiring a uterine ultrasound image and displaying the uterine ultrasound image through a display interface of a display;

determining a first characteristic point of a first side endometrium of the endometrium ultrasonic image, wherein the first characteristic point comprises a characteristic point positioned at a cervix and a characteristic point positioned at a fundus; wherein the first side endometrium comprises the pre-or post-endometrium of the endometrium; according to the trend of the endometrium, automatically connecting the first characteristic points comprising the characteristic points of the cervix and the characteristic points of the uterine fundus to form a first boundary line of the first side endometrium; generating a second boundary line from the first boundary line away from the first lateral intima and proximate to the myometrium; determining a region between at least the first boundary line and the second boundary line in the uterine ultrasound image as the region of interest.

Referring to fig. 15, first to fourth feature points 1 to 4 of the anterior uterine membrane are determined, and the feature points 1 to 4 are automatically connected to form an anterior membrane boundary line; generating a second boundary line (as a curve indicated by the characteristic points 1 'to 4') from the anterior membrane boundary line at a position distant from the first side endomembrane and close to the myometrium, i.e. at a side distant from the uterine cavity from the anterior membrane boundary line, which may be referred to as a joint band boundary line; a region between a front film boundary line and the second boundary line may be determined as the region of interest. For example, two ends of the front film boundary line and the second boundary line are respectively connected, and the enclosed area is the region of interest. Of course, also without limitation, the region of interest may also include, for example, at least one of the following: a uterine fundus area, a cervical area, an anterior membrane boundary line, the posterior membrane boundary line, and an area between any two of the uterine cavity lines.

For example, the second boundary line may be obtained by copying and moving the first boundary line, or may be obtained by determining feature points indicating the second boundary line from the perpendicular to the first boundary line, such as feature point 1 'to feature point 4' in fig. 15, and automatically connecting these feature points.

Referring to fig. 16 in combination with the foregoing embodiments, fig. 16 is a flowchart illustrating a method for determining a region of interest in an ultrasound image according to still another embodiment of the present application.

As shown in fig. 16, the method of the embodiment of the present application includes steps S510 to S540.

S510, acquiring an ultrasonic image of the uterus, and displaying the ultrasonic image of the uterus through a display interface of a display.

S520, determining a third characteristic point of endometrium in the uterine ultrasonic image, wherein the third characteristic point comprises a characteristic point positioned at a cervix and a characteristic point positioned at a uterine fundus.

Referring to fig. 17, the third feature points of the endometrium include feature points 1 to 6, wherein feature point 1 and/or feature point 6 are feature points located at the fundus of the uterus, and feature point 4 and/or feature point 5 are feature points located at the cervix.

Illustratively, a third feature point of the endometrium in the ultrasound image of the uterus is determined based on image recognition, and/or feature point selection operations by the user. For example, the third feature point may be manually determined by the user, may be automatically determined, or may be manually adjusted by the user after the automatic determination, and the foregoing embodiment of determining the first feature point may be referred to, which is not described herein.

And S530, automatically connecting the third characteristic points one by one according to the trend of the endometrium and the shortest path to form an endometrium boundary line of the endometrium.

Referring to fig. 17, adjacent third feature points are sequentially connected according to the shortest path to form an endometrium boundary line of the endometrium; as shown in fig. 17, the endometrium boundary line may or may not be closed, and for example, the endometrium boundary line may be a curve segment from the feature point 1 to the feature point 5 to the feature point 6 via the feature point 2.

By way of example, the third feature points are automatically connected one by one according to the shortest path to form the endometrium boundary line of the endometrium, so that the user is not required to determine the third feature points according to a specific sequence, and the flexibility is higher. For example, according to a preset path planning algorithm, the third feature points are automatically connected one by one according to the shortest path to form an endometrium boundary line of the endometrium.

The connection line between the adjacent third feature points can be a straight line, so that the operation amount is small, and the data processing efficiency is high; nor is it of course limited thereto. For example, the line between adjacent third feature points may be an arc.

In some embodiments, the method further comprises: identifying the area where the endometrium is located, and determining the trend of the endometrium according to the area where the endometrium is located; or identifying the lateral endometrium of the endometrium, and determining the trend of the endometrium according to the trend of the lateral endometrium of the endometrium.

In some embodiments, the automatically connecting the third feature points one by one according to the shortest path to form an endometrium boundary line of the endometrium according to the trend of the endometrium comprises: selecting a starting point from the third feature points; and connecting the starting points one by one in a counter-clockwise/clockwise direction and in a shortest path to form an endometrium boundary line of the endometrium.

Illustratively, the starting point is a feature point located at the cervix uteri or a feature point at the fundus among the third feature points.

For example, referring to fig. 17, the starting point is the fundus feature point 1 of the endometrium and the ending point is the cervical feature point 6 of the endometrium.

S540, determining at least the area between the endometrium boundary lines in the uterine ultrasound image as the region of interest.

Referring to fig. 17, the region between the inner membrane boundary lines is the region of interest, which is not limited thereto.

Illustratively, the region of interest further comprises: a fundus region is created at an end of the anterior and posterior membrane boundary lines near the fundus and/or a cervical region is created at an end near the cervix. Reference may be made specifically to the description of the fundus and cervical regions in the foregoing embodiments, and no further description is given here.

Referring to fig. 2 in conjunction with the above examples, fig. 2 is a schematic block diagram of ultrasound imaging apparatus 10 in one embodiment.

As shown in fig. 2, the ultrasound imaging apparatus 10 includes at least a probe 100; a transmitting circuit 101, said transmitting circuit 101 exciting said probe 100 to transmit ultrasound waves to the uterus; a receiving circuit 103, wherein the receiving circuit 103 controls the probe 100 to receive ultrasonic echo so as to obtain an ultrasonic echo signal; and the display is used for providing a display interface.

The ultrasound imaging device 10 processes the ultrasound echo signals to obtain ultrasound images of the uterus. For example, referring to fig. 2, the beam forming circuit 104 in the ultrasound imaging device 10 performs beam forming processing on the ultrasound echo signals/data, and then sends the processed signals/data to the processor 105. The processor 105 may process the ultrasound echo signals/data to obtain ultrasound images of the uterus.

The ultrasound imaging device 10 is further adapted to perform the steps of the method of determining a region of interest in an ultrasound image of the uterus as described above. For example, the ultrasound imaging device 10 includes one or more processors 105, the one or more processors 105 working individually or together to perform the steps of a method of determining a region of interest in an ultrasound image in which a region of interest is determined.

The ultrasonic imaging device 10 is further configured to extract and process an ultrasonic echo signal of the region of interest, so as to obtain peristaltic motion parameters of the region of interest; and displaying a chart of the peristaltic movement parameters of the region of interest over time through a display interface of the display.

The specific principle and implementation manner of the ultrasound imaging device provided in the embodiment of the present application are similar to the method for determining the region of interest in the ultrasound image in the foregoing embodiment, and are not repeated herein.

The present application further provides a computer readable storage medium storing a computer program, where the computer program when executed by a processor causes the processor to implement the steps of the method for determining a region of interest in an ultrasound image provided in the foregoing embodiment.

The computer readable storage medium may be an internal storage unit of the ultrasound imaging device according to any of the foregoing embodiments, for example, a hard disk or a memory of the ultrasound imaging device. The computer readable storage medium may also be an external storage device of the ultrasound imaging apparatus, such as a plug-in hard disk, a Smart Media Card (SMC), a Secure Digital (SD) Card, a Flash memory Card (Flash Card), or the like, which are provided on the ultrasound imaging apparatus.

It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

It should also be understood that the term "and/or" as used in this application and the appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes such combinations.

While the invention has been described with reference to certain preferred embodiments, it will be understood by those skilled in the art that various changes and substitutions of equivalents may be made and equivalents will be apparent to those skilled in the art without departing from the scope of the invention. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims

1. A method for determining a region of interest in an ultrasound image, comprising:

2. The method of claim 1, wherein the first characteristic points of endometrium in the ultrasound image of uterus comprise characteristic points of endometrium on a first side and characteristic points of endometrium on a second side,

the first side endomembrane is a endometrial membrane, the second side endomembrane is a endometrial membrane, or the first side endomembrane is a endometrial membrane, and the second side endomembrane is a endometrial membrane;

said automatically connecting said first characteristic points including characteristic points of said cervix and characteristic points of said fundus according to the trend of said endometrium, comprising:

Automatically connecting characteristic points of the cervix including the first side endometrium and characteristic points of the fundus according to the trend of the endometrium to form a first side endometrium boundary line,

according to the trend of the endometrium, automatically connecting the characteristic points of the cervix comprising the second side endometrium and the characteristic points of the fundus to form a second side endometrium boundary line;

the determining that at least the area between the endometrium boundary lines in the uterine ultrasound image is the region of interest comprises:

3. The method of claim 1, wherein the endometrium comprises a first side endometrium and a second side endometrium, the first feature points of the endometrium in the ultrasound image of the uterus comprise feature points located on the first side endometrium, the first side endometrium being either the pre-uterine or the post-uterine membrane;

said automatically connecting said first feature points including said cervical feature points and said uterine fundus feature points according to said endometrial trend to form an endometrial boundary line of said endometrium, comprising:

According to the trend of the endometrium, automatically connecting the characteristic points of the cervix and the characteristic points of the fundus of the uterus one by one to form a first side endometrium boundary line;

and generating a second side inner membrane boundary line at a position close to the second side inner membrane according to the first side inner membrane boundary line.

4. A method according to claim 3, wherein said generating a second side intima boundary line from said first side intima boundary line at a location proximate to said second side intima comprises:

copying the first side inner membrane boundary line and moving a first preset distance to the direction of the second side inner membrane to obtain the second side inner membrane boundary line.

5. The method of claim 3, wherein the first feature points of endometrium in the ultrasound image of uterus further comprise feature points located on the second side endometrium;

the generating a second side inner membrane boundary line at a position close to the second side inner membrane according to the first side inner membrane boundary line comprises:

copying the first side inner membrane boundary line and moving to coincide with at least one characteristic point of the second side inner membrane to obtain the second side inner membrane boundary line.

6. The method of claim 1, wherein the endometrium comprises a first side endometrium and a second side endometrium,

a first characteristic point of endometrium in the uterine ultrasound image comprises a characteristic point of endometrium positioned at the first side;

the first characteristic points of the endometrium in the uterine ultrasonic image further comprise characteristic points positioned on the second side endometrium;

the characteristic points of the second side inner film comprise points which are close to the second side inner film according to the vertical line direction of the characteristic points of the first side inner film and have a second preset distance from the characteristic points of the first side inner film, or the characteristic points of the second side inner film comprise points which are close to the second side inner film and have a third preset distance from the characteristic points of the first side inner film according to the vertical line direction of the boundary line generated by the characteristic points of the first side inner film.

7. The method of claim 6, wherein said automatically connecting said first feature points including feature points of said cervix and feature points of said fundus according to a trend of said endometrium forms an endometrium boundary line of said endometrium, comprising:

According to the trend of the endometrium, automatically connecting characteristic points of a cervix and characteristic points of a fundus positioned on the first side endometrium to form a first side endometrium boundary line of the endometrium;

according to the trend of the endometrium, automatically connecting the characteristic points of the cervix and the characteristic points of the fundus of the uterus which are positioned on the second side endometrium to form a second side endometrium boundary line of the endometrium.

8. The method of claim 7, wherein forming the feature points of the second side intima boundary line comprises: and the first characteristic points are located at the characteristic points of the second side inner film, and the points which are close to the second side inner film according to the vertical line direction of the characteristic points of the first side inner film and have the distance of a second preset distance from the characteristic points of the first side inner film.

9. The method of any one of claims 1-8, wherein the region of interest further comprises:

generating a uterine fundus area according to the characteristic points positioned at the uterine fundus, and/or generating a uterine neck area according to the characteristic points positioned at the uterine neck.

10. The method of claim 9, wherein the step of determining the position of the substrate comprises,

when the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus area is a circular area, and the cervical area is a rectangular area;

When the uterine ultrasound image is a cross section ultrasound image, the uterine fundus area and the cervical area are both circular areas.

11. The method according to claim 10, wherein the circular area is tangential to the intima boundary line at least at one point and/or at least one vertex of the rectangular area is located on the intima boundary line.

12. The method according to any one of claims 9-11, wherein said generating a fundus region from said fundus located feature points and/or generating a cervical region from said cervical located feature points comprises:

generating the uterine fundus area according to the boundary line end point positioned at the uterine fundus on the endometrium boundary line in the uterine ultrasound image;

and generating the cervical region according to the boundary line end point of the endometrium boundary line positioned at the cervical in the uterine ultrasonic image.

13. The method of any one of claims 1-8, wherein the determining a first feature point of endometrium in the ultrasound image of uterus comprises:

and determining a first characteristic point of endometrium in the uterine ultrasound image based on image identification and/or characteristic point selection operation of a user.

14. The method according to any one of claims 1-8, further comprising:

identifying the area where the endometrium is located, and determining the trend of the endometrium according to the area where the endometrium is located; or (b)

Identifying the lateral endometrium of the endometrium, and determining the trend of the endometrium according to the trend of the lateral endometrium of the endometrium.

15. A method for determining a region of interest in an ultrasound image, comprising:

16. The method of claim 15, wherein the first characteristic points of endometrium in the ultrasound image of uterus comprise characteristic points of endometrium on a first side and characteristic points of endometrium on a second side,

according to the trend of the endometrium, automatically connecting the first characteristic points one by one from the characteristic points at one end of the endometrium to the characteristic points at the other end of the endometrium to form an endometrium boundary line of the endometrium, and comprising the following steps:

automatically connecting the characteristic points at one end of the first side endometrium to the characteristic points at the other end one by one according to the trend of the endometrium to form a first side endometrium boundary line;

automatically connecting the characteristic points positioned at one end of the second side endometrium to the characteristic points positioned at the other end one by one according to the trend of the endometrium to form a second side endometrium boundary line;

17. The method of claim 15, wherein the first feature point of the endometrium in the ultrasound image of the uterus comprises a feature point of the endometrium on a first side, the first side endometrium being either the pre-uterine or the post-uterine membrane;

according to the trend of the endometrium, automatically connecting the characteristic points positioned at one end of the first side endometrium to the characteristic points positioned at the other end one by one to form a first side endometrium boundary line;

and generating a second side inner film boundary line at a position close to a second side inner film according to the first side inner film boundary line, wherein the second side inner film and the first side inner film are inner films on different sides.

18. The method of claim 17, wherein generating a second side intima boundary line from the first side intima boundary line at a location proximate to a second side intima comprises:

Copying the first side inner membrane boundary line and moving the ultrasonic imaging device in the direction of the second side inner membrane to obtain the second side inner membrane boundary line.

19. The method of claim 17, wherein the first feature points of endometrium in the ultrasound image of uterus further comprise feature points of endometrium located on the second side;

20. The method of claim 16 or 19, wherein said determining a first feature point of endometrium in the ultrasound image of uterus comprises:

determining a characteristic point of a first side endometrium of the endometrium in the uterine ultrasound image;

and taking a point which is close to the second side inner film in the vertical direction according to the characteristic point of the first side inner film and is at a second preset distance from the characteristic point of the first side inner film as the characteristic point of the second side inner film, or taking a point which is close to the second side inner film in the vertical direction according to the boundary line generated by the characteristic point of the first side inner film and is at a third preset distance from the characteristic point of the first side inner film as the characteristic point of the second side inner film, wherein the vertical line passes through the characteristic point of the first side inner film.

21. The method of any one of claims 15-20, wherein the region of interest further comprises:

22. The method of claim 21, wherein the step of determining the position of the probe is performed,

23. The method of claim 22, wherein the step of determining the position of the probe is performed,

the circular area is tangent to the intima boundary line at least at one point and/or at least one vertex of the rectangular area is located on the intima boundary line.

24. The method according to any one of claims 21-23, wherein said generating a fundus region from said fundus located feature points and/or generating a cervical region from said cervical located feature points comprises:

25. A method for determining a region of interest in an ultrasound image, comprising:

wherein the first side endomembrane is a endometrial membrane, the second side endomembrane is a endometrial membrane, or,

the first side endometrium is a posterior endometrium, and the second side endometrium is an anterior endometrium;

26. The method of claim 25, wherein forming the feature points of the second side intima boundary line comprises: and the first characteristic points are located at the characteristic points of the second side inner film, and the points which are close to the second side inner film according to the vertical line direction of the characteristic points of the first side inner film and have the distance of a second preset distance from the characteristic points of the first side inner film.

27. The method of claim 25 or 26, wherein the region of interest further comprises:

28. A method for determining a region of interest in an ultrasound image, comprising:

29. The method of claim 28, wherein the generating anterior and posterior membrane boundary lines based on the uterine cavity line comprises:

moving the uterine cavity line to a first side endometrium position to obtain a first side endometrium boundary line, wherein the first side endometrium is the pre-uterine membrane or the post-uterine membrane;

and copying the first side inner membrane boundary line and moving to the position of the second side inner membrane to obtain a second side inner membrane boundary line, wherein the second side inner membrane and the first side inner membrane are inner membranes on different sides.

30. The method of claim 29, wherein the generating anterior and posterior membrane boundary lines based on the uterine cavity line comprises:

copying the uterine cavity lines to obtain two uterine cavity lines;

moving one of the two uterine cavity lines to the position of the anterior uterine membrane to obtain the anterior membrane boundary line;

and moving the other of the two uterine cavity lines to the direction of the endometrium to obtain the posterior membrane boundary line.

31. The method of claim 30, wherein the generating anterior and posterior membrane boundary lines based on the uterine cavity line comprises:

determining feature points of the endometrium and feature points of the endometrium based on the intrauterine line and the second feature points;

the anterior membrane boundary line is determined from the characteristic points of the endometrium, and the posterior membrane boundary line is determined from the characteristic points of the endometrium.

32. The method of claim 31, wherein the determining the characteristic points of the endometrium and the characteristic points of the endometrium based on the intrauterine line and the second characteristic points comprises:

a point which is close to the endometrium in the normal direction or the vertical direction of the uterine cavity line and has a third preset distance from the second characteristic point is taken as the characteristic point of the endometrium;

and taking a point which is close to the endometrium in the normal direction or the vertical direction of the curve corresponding to the uterine cavity line and has a distance from the second characteristic point of a fourth preset distance as the characteristic point of the endometrium.

33. The method of any one of claims 28-32, wherein the region of interest further comprises:

A fundus region is created at an end of the anterior and posterior membrane boundary lines near the fundus and/or a cervical region is created at an end near the cervix.

34. The method of claim 28, wherein the step of providing the first information comprises,

when the uterine ultrasound image is a longitudinal section ultrasound image, the uterine fundus area is a circular area, and the cervical area is a rectangular area; and/or

35. The method of claim 34, wherein the step of determining the position of the probe is performed,

the circular region is tangent to the front film boundary line or the rear film boundary line at least at one point, and/or

At least one vertex of the rectangular region is located on the front film boundary line or the rear film boundary line.

36. The method according to any one of claims 33-35, wherein said generating a fundus region from said fundus located feature points and/or generating a cervical region from said cervical located feature points comprises:

generating the uterine fundus area according to a boundary line endpoint of the anterior membrane boundary line positioned at the uterine fundus and a boundary endpoint of the posterior membrane boundary line positioned at the uterine fundus in the uterine ultrasound image; and/or

And generating the uterine fundus area according to the boundary line end point of the anterior membrane boundary line positioned at the cervix and the boundary line end point of the posterior membrane boundary line positioned at the cervix in the uterine ultrasound image.

37. A method for determining a region of interest in an ultrasound image, comprising:

38. A method for determining a region of interest in an ultrasound image, comprising:

39. A method for determining a region of interest in an ultrasound image, comprising:

40. A method for determining a region of interest in an ultrasound image, comprising:

41. The method of claim 40, further comprising:

42. The method according to claim 40 or 41, wherein said automatically connecting the third feature points one by one according to the shortest path in accordance with the trend of the endometrium to form an endometrium boundary line of the endometrium comprises:

selecting a starting point from the third feature points;

and connecting the starting points one by one in a counter-clockwise/clockwise direction and in a shortest path to form an endometrium boundary line of the endometrium.

43. The method of claim 42, wherein the starting point is a feature point located at the cervix uteri or a feature point at the fundus among the third feature points.

44. An ultrasonic imaging apparatus, comprising:

a probe;

a display providing a display interface;

the ultrasonic imaging equipment processes the ultrasonic echo signals to obtain uterine ultrasonic images; and performing the method of determining a region of interest in an ultrasound image as claimed in any one of claims 1 to 43, determining a region of interest in the uterine ultrasound image;

45. A computer readable storage medium storing a computer program which, when executed by a processor, causes the processor to implement:

the method for determining a region of interest in an ultrasound image as claimed in any one of claims 1 to 43.