CN116139397A - Magneto-acoustic coupling stimulation device attached to skull and operation method of stimulation device - Google Patents
Magneto-acoustic coupling stimulation device attached to skull and operation method of stimulation device Download PDFInfo
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- CN116139397A CN116139397A CN202310008989.XA CN202310008989A CN116139397A CN 116139397 A CN116139397 A CN 116139397A CN 202310008989 A CN202310008989 A CN 202310008989A CN 116139397 A CN116139397 A CN 116139397A
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- A61N1/00—Electrotherapy; Circuits therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/002—Magnetotherapy in combination with another treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
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Abstract
The embodiment of the invention discloses a magneto-acoustic coupling stimulation device attached to a skull and an operation method of the stimulation device. The magnetoacoustic coupling stimulation device for attaching the skull comprises: the helmet body comprises a head accommodating part. The alternating magnetic field emission module is used for emitting electromagnetic wave beams to the to-be-treated part of the head of the to-be-treated object, the alternating magnetic field emission module comprises a liquid metal coil, the liquid metal coil comprises a hose, liquid metal is stored in the hose, the liquid metal coil is arranged on the second side, and the head of the to-be-treated object is attached to the hose. And the ultrasonic wave transmitting module is used for transmitting ultrasonic wave beams to the to-be-treated part. The liquid metal coil can be tightly attached to the scalp of the object to be treated for coil shaping, compared with the traditional magnetic stimulation coil, the distance between the object to be treated and the coil can be greatly reduced, the intracranial induction current intensity is greatly improved, the intracranial electric stimulation effect of transcranial magnetic stimulation is improved, and the transcranial magnetoacoustic coupling electric stimulation effect is further improved.
Description
Technical Field
The embodiment of the invention relates to a magneto-acoustic coupling technology, in particular to a magneto-acoustic coupling stimulation device attached to a skull and an operation method of the stimulation device.
Background
Transcranial magnetoacoustic stimulation (transcranial magneto-acoustical stimulation, TMAS) is a novel noninvasive nerve electrical stimulation technique that can achieve both stimulation focusing and stimulation depth. The method is different from the mode of directly utilizing the change of an electric field and a magnetic field to induce electric stimulation, but based on the magneto-acoustic coupling effect of conductive tissues, the method utilizes the high focusing characteristic of ultrasound to generate a focusing electric field with the same space-time distribution as that of the ultrasound field in the presence of a static magnetic field, so that the noninvasive electric stimulation with high spatial resolution is realized. The stimulation method can realize the transcranial accurate electrical stimulation of the mm magnitude including the deep brain region.
However, the intensity of the magnetoacoustic coupling focusing electric field in the existing transcranial magnetoacoustic technology is low. And the electric field intensity of the magnetoacoustic coupling focusing electric field is determined by the ultrasonic sound pressure at the focusing point and the magnetic induction intensity of the magnetic field. In the present situation that the magnetic field in the transcranial magnetoacoustic stimulation system is a static magnetic field, the magnetic field can be provided by a permanent magnet or an electromagnet, and the magnetic induction intensity is approximately 0.1T-0.8T. Especially in view of the non-uniform distribution of the magnetic field in space, the magnetic field strength of the region to be treated is lower.
Disclosure of Invention
The invention provides a magneto-acoustic coupling stimulation device attached to a skull and an operation method of the stimulation device, so as to enhance the magnetic field intensity and improve the stimulation intensity and the treatment effect of the magneto-acoustic coupling stimulation device.
In a first aspect, an embodiment of the present invention provides a magnetoacoustic coupling stimulation device for fitting a skull, including:
the head cap comprises a head cap body, wherein the head cap body comprises a head accommodating part, the head accommodating part comprises a first side and a second side far away from the first side, and a groove is formed on the first side and is used for accommodating the head of a to-be-treated object;
the alternating magnetic field emission module is used for emitting electromagnetic wave beams to a to-be-treated part of the head of the to-be-treated object, the alternating magnetic field emission module comprises a liquid metal coil, the liquid metal coil comprises a hose, liquid metal is stored in the hose, the liquid metal coil is arranged on the second side, and the head of the to-be-treated object is attached to the liquid metal coil;
the ultrasonic wave transmitting module is used for transmitting ultrasonic wave beams to the to-be-treated part, the ultrasonic wave transmitting module comprises an ultrasonic transducer, the ultrasonic transducer is arranged on the helmet body and is attached to the head of the to-be-treated object.
Wherein, the included angle between the ultrasonic wave beam and the electromagnetic wave beam at the part to be treated is more than 0 degree.
Optionally, the headgear body further includes a plurality of fixing columns, the fixing columns are disposed on the second side, and the liquid metal coil is disposed between the fixing columns.
Optionally, the shape of the liquid metal coil between the fixing posts is annular, double-annular or S-shaped.
Optionally, the liquid metal comprises gallium or gallium-based liquid metal.
Optionally, the gallium-based liquid metal comprises gallium indium tin liquid metal.
Optionally, a liquid metal delivery pump is further included for delivering the liquid metal to the hose.
Optionally, an included angle between the ultrasonic wave beam and the electromagnetic wave beam at the to-be-treated part is 90 degrees.
Optionally, the ultrasonic transmitting module further comprises a pulsed ultrasonic excitation source for providing excitation to the ultrasonic transducer.
Optionally, the ultrasonic transducer further comprises a control part, wherein the control part adjusts the focal position of the ultrasonic transducer by adjusting the output parameter of the pulse ultrasonic excitation source.
In a second aspect, an embodiment of the present invention further provides a method for operating a magneto-acoustic coupling stimulation device attached to a skull, which is performed by any one of the magneto-acoustic coupling stimulation devices attached to a skull, including:
adjusting the liquid metal coil to a preset shape;
determining the positions of the electromagnetic wave beam and the ultrasonic wave beam according to the part to be treated, and setting the positions of the ultrasonic transducer and the liquid metal coil according to the positions of the electromagnetic wave beam and the ultrasonic wave beam;
and starting the alternating magnetic field emission module and the ultrasonic emission module to start magneto-acoustic coupling stimulation.
In the embodiment of the invention, the liquid metal coil can be tightly attached to the scalp of the object to be treated for coil shaping, compared with the traditional magnetic stimulation coil, the distance between the object to be treated and the coil can be greatly reduced, the intracranial induction current intensity is greatly improved, the intracranial electric stimulation effect of transcranial magnetic stimulation is improved, meanwhile, the device can instantly realize the magnetic induction intensity of 1-3T based on the increase of the alternating current intensity while reducing the cost, and further the transcranial magnetoacoustic coupling electric stimulation effect is improved. On the other hand, the liquid metal coil is matched with the head cap body, and the liquid metal coil can be molded into a shape which is not limited to a round shape, so that various magneto-acoustic coupling stimulation can be conveniently carried out. Moreover, the liquid metal has the characteristics of high electrical conductivity and high thermal conductivity, so that the effect of an electric field can be further improved, and the influence of the ultrasonic stimulation on the thermal effect of the part to be treated is reduced. In other embodiments, the liquid metal in the overheated liquid metal coil is replaced at any time by using a liquid metal delivery pump, so that the working temperature is further reduced, the rated current and voltage amplitude of the metal coil for emitting electromagnetic waves are improved, and the magneto-acoustic coupling stimulation effect is improved.
Drawings
Fig. 1 is a schematic structural diagram of a magneto-acoustic coupling stimulation device for attaching a skull according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of another magneto-acoustic coupling stimulation device for attaching a skull according to an embodiment of the present invention;
fig. 3 is a schematic diagram of the working principle of a magneto-acoustic coupling stimulation device for attaching a skull according to an embodiment of the present invention;
fig. 4 is a method step diagram of an operation method of a magneto-acoustic coupling stimulation device for attaching a skull according to an embodiment of the present invention.
Detailed Description
The invention is described in further detail below with reference to the drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting thereof. It should be further noted that, for convenience of description, only some, but not all of the structures related to the present invention are shown in the drawings.
Transcranial magnetoacoustic stimulation is a noninvasive electrical stimulation technique based on magnetoacoustic coupling effects of conductive tissues, which utilizes the high focusing characteristics of ultrasound to achieve high spatial resolution. The basic principle is as follows: the conductive particles in the tissue vibrate by ultrasonic excitation, and under the existence of a magnetic field (generally a static magnetic field) perpendicular to the vibration direction of the particles, the conductive particles are acted by Lorentz force, and positive and negative particles deflect and converge towards two ends of the tissue along the vector product direction of the static magnetic field and the ultrasonic field, so that an internal induction electric field is formed. For conductive biological tissue placed in static magnetic field, if ultrasonic signal is injected along one direction, internal coupling electric field and coupling current with same frequency can be produced in the direction perpendicular to both static magnetic field and sound field direction in the interior of tissue based on magnetoacoustic coupling effect. The magnitude of the coupling electric field and the magnetic induction intensity of the ultrasonic sound pressure and the magnetic field are in linear relation, and the direction is the vector product direction of the ultrasonic sound field and the static magnetic field. Therefore, the transcranial magnetoacoustic stimulation system can emit focused ultrasound by using a focused ultrasound transducer, and an animal or human body part to be stimulated is placed in a static magnetic field, so that a magnetoacoustic coupling stimulation electric field is formed at an ultrasound focus inside the tissue to be stimulated. The TMAS technology introduces a static magnetic field perpendicular to the ultrasonic propagation direction, generates focused electrical stimulation through a magneto-acoustic coupling effect, and superimposes focused ultrasonic stimulation, wherein the electrical stimulation direction is orthogonal to the ultrasonic stimulation direction. Therefore, the intensity of the magnetic field directly influences the intensity of the magnetoacoustic coupling stimulation compound field including the magnetoacoustic coupling stimulation electric field, so that how to increase the magnetic field of the part to be treated is important.
Fig. 1 is a schematic structural diagram of a magneto-acoustic coupling stimulation device for attaching a skull according to an embodiment of the present invention, and fig. 2 is a schematic structural diagram of another magneto-acoustic coupling stimulation device for attaching a skull according to an embodiment of the present invention, see fig. 1 and fig. 2. The embodiment of the invention provides a magneto-acoustic coupling stimulation device for attaching a skull, which comprises the following components:
the head cap comprises a head cap body 1, wherein the head cap body 1 comprises a head accommodating part 11, the head accommodating part 11 comprises a first side and a second side far away from the first side, and the first side is provided with a groove for accommodating the head of a to-be-treated object;
the alternating magnetic field emission module 2 is used for emitting electromagnetic wave beams to a to-be-treated part of the head of the to-be-treated object, the alternating magnetic field emission module 2 comprises a liquid metal coil 21, the liquid metal coil 21 comprises a hose, liquid metal is stored in the hose, the liquid metal coil 21 is arranged on the second side, and the head of the to-be-treated object is attached to the hose;
the ultrasonic wave transmitting module 3 is used for transmitting ultrasonic wave beams to the to-be-treated part, the ultrasonic wave transmitting module 3 comprises an ultrasonic transducer 31, the ultrasonic transducer 31 is arranged on the head cap body 1, and the head of the to-be-treated object is attached to the head of the to-be-treated object.
Wherein, the included angle between the ultrasonic wave beam and the electromagnetic wave beam at the part to be treated is more than 0 degree.
The helmet body 1 is used for supporting or placing a liquid metal coil 21. In use, the headgear body 1 may be worn on the head of a subject to be treated for stimulation and treatment. The head receiving portion 11 in the head cap body 1 may include a head receiving liner made of elastic cloth or a head receiving inner helmet made of 3D printing technology. The first side of the head accommodation part 11 is the inner side for cladding and accommodating the treatment to be treatedA subject header. The second side is the outer side where the liquid metal coil 21 can be placed. In other embodiments, the headgear body 1 further includes a plurality of fixing posts 4, the fixing posts 4 being disposed on the second side, and the liquid metal coil 21 being located between the fixing posts 4. The fixing columns 4 can be arranged in a matrix manner or can be in any distribution pattern according to actual needs. The liquid metal coil 21 can be molded into any shape according to actual needs and is arranged in the gap of the fixing column 4 closely to the head of the object to be treated, and the shape of the liquid metal coil 21 is maintained by the fixing column 4. The liquid metal coil 21 is facilitated to be shaped and fixed again. The shape of the liquid metal coil 21 between the fixing posts 4 may be, for example, annular, double annular or S-shaped. Since the alternating magnetic field generated by the annular liquid metal coil 21 is concentrated and the magnetic field focusing capability is high, the annular liquid metal coil 21 will be described as an example. The liquid metal coil 21 includes a hose, which may be made of soft material such as rubber. The liquid metal coil 21 is obtained by filling the hose with liquid metal. The alternating magnetic field emission module 2 may further include an alternating magnetic field exciter. An alternating magnetic field exciter is used to provide excitation power to the coil. The alternating magnetic field exciter generally comprises a charging circuit, an energy storage capacitor, a pulse shaping circuit and a thyristor switch. The exciter charges an energy storage capacitor after rectification by a high-voltage power supply, and realizes the output of alternating current through the charging and discharging of the capacitor. The alternating magnetic field exciter may generate an alternating current of a certain repetition frequency (e.g. 1 Hz) and a certain pulse width (e.g. 280 mus) to excite the liquid metal coil 21 as an alternating coil. In other embodiments, the liquid metal comprises gallium or gallium-based liquid metal. Illustratively, the gallium-based liquid metal includes gallium indium tin liquid metal. The liquid metal has the advantages of high heat dissipation, high electromagnetic shielding property, high heat conductivity, high corrosion resistance and the like. The rubber pipeline can be used as a hose for injecting liquid metal, has the characteristics of softness, easiness in shaping and the like, can be bent to form various coil shapes, can provide an insulating medium environment for the liquid metal coil 21, and improves the safety of the magneto-acoustic coupling stimulation device. Based on electromagnetic induction theory, the liquid metal coil 21 can be used under the excitation of the alternating magnetic field exciterAn alternating magnetic field with a repetition frequency of 280 mus at 1Hz was generated. The ultrasonic wave transmitting module 3 includes an ultrasonic transducer 31, and the outer shell of the ultrasonic transducer 31 is directly connected with the helmet body 1. Because the magnetoacoustic coupling electric field is the vector product of the ultrasonic field and the magnetic field, it is necessary to ensure that the included angle between the ultrasonic beam and the electromagnetic wave beam at the part to be treated is greater than 0 degrees. When the included angle between the ultrasonic wave beam and the electromagnetic wave beam at the part to be treated is 90 degrees, the intensity of the magnetoacoustic coupling electric field is maximum, and the stimulation and treatment effects are best. Therefore, the position and the posture between the liquid metal coil 21 and the ultrasonic transducer 31 can be adjusted with the aim that the included angle between the ultrasonic wave beam and the electromagnetic wave beam at the part to be treated is 90 degrees. The focusing ultrasonic transducer generally adopts a single array element focusing transducer or a phased array focusing ultrasonic transducer. The main frequency of the focused ultrasound transducer is typically 0.3-5MHz, and frequency selection can be made based on the depth of stimulation of the subject to be measured. The ultrasound transmission module 3 further comprises a pulsed ultrasound excitation source. The pulsed ultrasonic excitation source may be a single-channel pulsed ultrasonic excitation source or a multi-channel pulsed ultrasonic excitation source. The pulse ultrasonic excitation source provides excitation for the focusing ultrasonic transducer, and the number of channels of the excitation source is consistent with the number of the array elements of the transducer so as to ensure that each channel can be excited independently for each array element. In other embodiments, a control section is also included that adjusts the focal position of the ultrasonic transducer 31 by adjusting the output parameters of the pulsed ultrasonic excitation source. The control part may include a Personal Computer (PC) or an industrial personal computer. In particular, in the case of using a multi-channel pulsed ultrasonic excitation source, the individual channel excitation parameters of the multi-channel pulsed ultrasonic excitation source are controlled by a PC/industrial personal computer. The pulse excitation parameters of each channel are adjusted by the PC/industrial personal computer, so that the transducer can send out focused ultrasonic pulse signals with adjustable focal length and focal position, and the excitation source and the PC can be realized by using a Verasonics ultrasonic development platform in the United states. Fig. 3 is a schematic diagram of the working principle of the magneto-acoustic coupling stimulation device for attaching the skull according to the embodiment of the invention, and refer to fig. 3. Wherein the x-direction, y-direction and z-direction are perpendicular to each other. By adjusting the relative positions of the alternating coil and the focusing ultrasonic transducer through adjusting the alternating coil fixing device and the transducer bracket, the focusing parallel to the x direction can be ensuredThe focused ultrasound field V is orthogonal to the alternating magnetic field B parallel to the y direction and is in the same spatial position. At this time, a magnetoacoustic coupling electric field parallel to the z direction can be generated in the vector product direction of the focusing sound field and the alternating magnetic field, namely E MA . At this time, the alternating coil also generates a magnetic induction electric field E in the target area to be stimulated M ，E M And E is connected with MA The directions are the same, the intensity is overlapped, and a composite physical field E in the same direction is formed in the target area M +E MA Further enhancing the stimulation electric field strength; in addition, the original focused ultrasound field V in the orthogonal direction can generate the focused composite field stimulation of three physical fields of the magnetoacoustic electric field, the magnetic induction electric field and the focused ultrasound field in the target area in the brain. In the embodiment of the invention, the liquid metal coil 21 can be directly attached to the scalp of the subject to be treated to form a coil shape, and the distance between the coil and the subject to be treated is greatly reduced, so that larger magnetic induction intensity can be provided. Greatly improves the intracranial induction current intensity and improves the intracranial electric stimulation effect of transcranial magnetic stimulation. Meanwhile, the power required by exciting the alternating coil is reduced, the magnetic induction intensity of 1-3T is instantaneously realized based on the increase of the alternating current intensity while the cost is reduced, and the transcranial magnetoacoustic coupling electric stimulation effect is further improved. The magnetic acoustic field generating device can be used for generating a focusing magnetic acoustic field based on the magneto-acoustic coupling effect at the part to be treated under the ultrasonic action, and simultaneously can be used for superposing an induction field generated by the pulse magnetic field and generating the composite stimulation of three physical fields of the focusing acoustic field, the magneto-acoustic field and the magnetic induction field at the part to be treated by the technology in addition to the original focusing ultrasonic field. Has better stimulation and treatment effects.
In other embodiments, the selected ultrasound transducer 31 may also be fixed to the transducer holder, and the focused ultrasound transducer position may be adjusted so that the focused ultrasound transducer may contact the site to be treated through the couplant. Then, the output parameters of the single-channel or multi-channel pulsed ultrasonic excitation source are adjusted so that the focal length and focal point of the ultrasonic transducer 31 meet the position of the portion to be treated. At the moment, the output of the alternating magnetic field exciter and the pulse ultrasonic excitation source is turned on, so that the accurate transcranial magnetoacoustic electric compound field stimulation can be carried out on the to-be-treated part. In the stimulation, the liquid metal coil 21 can be excited by adjusting the magnitude of the current output by the alternating magnetic field exciter so as to realize the construction of magnetic fields with different intensities at the to-be-treated part. The output size of the ultrasonic excitation source is adjusted to realize ultrasonic sound pressures with different intensities, so that the requirements of different stimulus intensities are further obtained. The stimulation in different directions can be realized by adjusting the relative positions of the focusing sound field and the alternating magnetic field.
In other embodiments, a liquid metal delivery pump is also included for delivering liquid metal to the hose.
The liquid metal in the overheated liquid metal coil 21 is replaced at any time by using the liquid metal delivery pump, so that the working temperature is further reduced, the rated current and voltage amplitude of the metal coil for emitting electromagnetic waves are improved, and the magneto-acoustic coupling stimulation effect is improved.
Fig. 4 is a method step diagram of an operation method of a magneto-acoustic coupling stimulation device for attaching a skull according to an embodiment of the present invention, see fig. 4. The embodiment of the invention also provides an operation method of the magneto-acoustic coupling stimulation device for attaching the skull, which is executed by any magneto-acoustic coupling stimulation device for attaching the skull and comprises the following steps:
s1: the liquid metal coil 21 is adjusted to a preset shape.
S2: the positions of the electromagnetic wave beam and the ultrasonic wave beam are determined according to the treatment site, and the positions of the ultrasonic transducer 31 and the liquid metal coil 21 are set according to the positions of the electromagnetic wave beam and the ultrasonic wave beam.
S3: the alternating magnetic field emission module 2 and the ultrasonic emission module 3 are started to perform magneto-acoustic coupling stimulation.
The liquid metal coil 21 is matched with the helmet body 1, and the liquid metal coil 21 can be molded into various shapes, not limited to a circular shape, so as to facilitate various types of magneto-acoustic coupling stimulation. The liquid metal coil 21 can be tightly attached to the scalp of the object to be treated for coil shaping, the distance between the object to be treated and the coil can be greatly reduced by intersecting with the traditional magnetic stimulation coil, the intracranial induction current intensity is greatly improved, the intracranial electric stimulation effect of transcranial magnetic stimulation is improved, meanwhile, the device can instantly realize the magnetic induction intensity of 1-3T based on the increase of the alternating current intensity while reducing the cost, and further the transcranial magnetoacoustic coupling electric stimulation effect is improved.
Note that the above is only a preferred embodiment of the present invention and the technical principle applied. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, and that various obvious changes, rearrangements, combinations, and substitutions can be made by those skilled in the art without departing from the scope of the invention. Therefore, while the invention has been described in connection with the above embodiments, the invention is not limited to the embodiments, but may be embodied in many other equivalent forms without departing from the spirit or scope of the invention, which is set forth in the following claims.
Claims (10)
1. A magneto-acoustic coupling stimulation device for fitting a skull, comprising:
the head cap comprises a head cap body, wherein the head cap body comprises a head accommodating part, the head accommodating part comprises a first side and a second side far away from the first side, and a groove is formed on the first side and is used for accommodating the head of a to-be-treated object;
the alternating magnetic field emission module is used for emitting electromagnetic wave beams to a to-be-treated part of the head of the to-be-treated object, the alternating magnetic field emission module comprises a liquid metal coil, the liquid metal coil comprises a hose, liquid metal is stored in the hose, the liquid metal coil is arranged on the second side, and the head of the to-be-treated object is attached to the liquid metal coil;
the ultrasonic wave transmitting module is used for transmitting ultrasonic wave beams to the to-be-treated part, the ultrasonic wave transmitting module comprises an ultrasonic transducer, the ultrasonic transducer is arranged on the helmet body and is attached to the head of the to-be-treated object.
Wherein, the included angle between the ultrasonic wave beam and the electromagnetic wave beam at the part to be treated is more than 0 degree.
2. The magneto-acoustic coupling stimulation device for the fitting of a skull of claim 1, wherein the headgear body further comprises a plurality of fixation posts disposed on the second side, the liquid metal coil being positioned between the fixation posts.
3. A magneto-acoustic coupling stimulation device for the fitting of the cranium according to claim 2, wherein the shape of the liquid metal coil between the fixation posts is annular, double annular or S-shaped.
4. The cranium-conforming magnetoacoustic coupling stimulation device of claim 1 wherein the liquid metal comprises gallium or gallium-based liquid metal.
5. The cranium-conforming magneto-acoustic coupling stimulation device of claim 4 wherein the gallium-based liquid metal comprises gallium indium tin liquid metal.
6. The cranium-fitting magnetoacoustic coupling stimulation device of claim 1 further comprising a liquid metal delivery pump for delivering the liquid metal to the hose.
7. The magneto-acoustic coupling stimulation apparatus for the attachment of a skull of claim 1, wherein the ultrasound beam and the electromagnetic wave beam form an angle of 90 degrees at the site to be treated.
8. The magneto-acoustic coupling stimulation apparatus of claim 1, wherein the ultrasound transmission module further comprises a pulsed ultrasound excitation source for providing excitation to the ultrasound transducer.
9. The magneto-acoustic coupling stimulation apparatus for the fitting of a skull of claim 8, further comprising a control portion that adjusts the focal position of said ultrasound transducer by adjusting the output parameters of said pulsed ultrasound excitation source.
10. A method of operating a magneto-acoustic coupling stimulation apparatus for fitting a skull, performed by a magneto-acoustic coupling stimulation apparatus for fitting a skull according to any of claims 1-9, comprising:
adjusting the liquid metal coil to a preset shape;
determining the positions of the electromagnetic wave beam and the ultrasonic wave beam according to the part to be treated, and setting the positions of the ultrasonic transducer and the liquid metal coil according to the positions of the electromagnetic wave beam and the ultrasonic wave beam;
and starting the alternating magnetic field emission module and the ultrasonic emission module to start magneto-acoustic coupling stimulation.
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| CN202310008989.XA CN116139397A (en) | 2023-01-04 | 2023-01-04 | Magneto-acoustic coupling stimulation device attached to skull and operation method of stimulation device |
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| CN202310008989.XA CN116139397A (en) | 2023-01-04 | 2023-01-04 | Magneto-acoustic coupling stimulation device attached to skull and operation method of stimulation device |
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