CN116078311A - High-flux reactor and system - Google Patents

Abstract

The invention discloses a high-throughput reactor, which comprises a reactor main body, a fluid flow dividing plate and a reactor cover. Wherein, the reactor main body is provided with a temperature control channel, a plurality of reaction channels are arranged around the temperature control channel, and each reaction channel is internally provided with a catalyst liner tube which can be rapidly disassembled; the fluid flow dividing plate is internally provided with a cavity capable of installing a micro-fluid chip, the micro-fluid chip comprises a chip inlet, a plurality of chip outlets and fluid limiting channels between the chip inlets and the chip outlets, and the micro-fluid chip is used for uniformly distributing fluid. The invention integrates the reactor main body, the fluid splitter plate provided with the micro-fluid chip and the reactor sealing cover into a high-flux reactor, is applied to a high-flux reactor system, and has more accurate control on the technological conditions such as airspeed, temperature, pressure and the like, and more convenient loading and unloading of the catalyst.

Description

High-flux reactor and system

Technical Field

The invention relates to the technical field of high-flux parallel reaction experiments, in particular to a high-flux reactor and a system.

Background

With the advent of the 4.0 era of industry, the development of intelligent high-throughput detection technology has been on the go. Catalysis is a basic stone in the chemical industry, and research and development of novel catalysts are always carried out in the industry so as to better meet the industrial application demands. The research and development of the catalyst are usually large in test amount, long in period and multiple in influencing factors, and the conventional single-channel reactor cannot meet the requirement of rapid screening of the catalyst. In order to improve the development efficiency, researchers introduce high-throughput detection technology into catalytic reaction evaluation, and a plurality of single-channel reactors are placed in parallel, so that parallel tests of a plurality of catalytic reactions are simultaneously carried out. In addition, small-scale experiments are performed in a small reactor with a few reagents and samples, which have special requirements for the reactor system used, in view of development efficiency, safety of the experiment, cost reduction, space saving, etc.

At present, most of reactor systems at home and abroad still adopt a traditional single-tube reactor parallel placement mode, and sample loading and unloading are complex and complicated. The temperature is usually controlled by adopting external heating modes such as a heating furnace, an oil bath, a sand bath and the like, the rising/cooling speed is slower, the time required for each channel to reach stability is longer, and the temperature deviation is larger. Conventional reactors still control the flow of a corresponding single reaction channel through a single or multiple mass flow controllers, with a corresponding back pressure valve being provided at each reaction channel outlet. The traditional flow and pressure control mode requires a large number of mass, flow controllers and back pressure valves, so that the equipment space and the cost are greatly increased. In order to better compare the experimental results executed in different reaction channels, a new technical means needs to be developed to accurately control the process conditions such as airspeed, temperature and pressure of the high-flux parallel reaction system.

Disclosure of Invention

Aiming at the defects in the prior art, the invention provides an integrated high-flux reactor and a system for realizing accurate control of reaction temperature and uniform distribution of fluid.

In order to achieve the aim of the invention, the invention adopts the following technical scheme:

there is provided a high throughput reactor comprising:

the reactor comprises a reactor main body, a plurality of reaction channels and a catalyst liner tube, wherein the reactor main body is provided with a temperature control channel, a plurality of reaction channels are arranged around the temperature control channel, and each reaction channel is internally provided with the catalyst liner tube; the side surface of the reactor main body is provided with a first fluid inlet, the upper end of the reactor main body is provided with a second fluid inlet, and the second fluid inlet is provided with a fifth sealing ring;

the bottom surface of the fluid flow dividing plate is provided with a third fluid inlet; the upper end of the fluid flow dividing plate is provided with a cavity for installing the micro-fluid chip, and the periphery of the cavity is provided with a sealing ring groove; a fourth fluid inlet and a corresponding sealing ring groove are formed in the cavity; a plurality of fluid outlets and corresponding sealing ring grooves are arranged around the fourth fluid inlet, and the fluid outlets penetrate through the fluid flow dividing plate and are communicated with the upper ends of the corresponding reaction channels;

the reactor cover seals the cavity by close combination with a sealing ring outside the cavity.

Further, a fluid channel penetrating the first fluid inlet and the second fluid inlet is formed in the reactor main body; a fluid channel which penetrates through the third fluid inlet and the fourth fluid inlet is formed in the fluid flow dividing plate; the second fluid inlet corresponds to the position of the third fluid inlet;

further, the microfluidic chip includes:

the chip main board is provided with a chip inlet at the center and a plurality of chip outlets around the chip inlet; the chip inlet and the chip outlet are connected through a fluid limiting channel, and the fluid limiting channel is etched in the chip main board; the chip inlet corresponds to the fourth fluid inlet, and the chip outlet corresponds to the fluid outlet;

and the center of the chip auxiliary plate is coaxial with the center of the chip main plate.

Further, the fluid restriction passage includes at least one of a first restriction passage, a second restriction passage, and a third restriction passage;

the first limiting channel is provided with a plurality of alternating wide channels and narrow channels, and two or more than two reaction fluids entering from the chip inlet are fully mixed by continuously splitting and converging the reaction fluids;

a second restriction channel which is one or a combination of a plurality of channels of a straight channel, a mixing channel and a unidirectional channel;

and the third limiting channel is uniformly provided with a plurality of convolution cavities, each convolution cavity comprises two funnel-shaped structures connected end to end, and the one-way circulation function of the convolution cavities can prevent fluid from flowing back.

Further, a first bolt counter bore and a second bolt counter bore are formed in the reactor sealing cover, the first bolt counter bore and the second bolt counter bore are uniformly and crosswise distributed on the edge of the reactor sealing cover, and the first bolt counter bore and the second bolt counter bore penetrate through the reactor sealing cover;

the fluid flow dividing plate is provided with a first threaded hole and a bolt through hole, the first threaded hole does not penetrate through the fluid flow dividing plate, and the bolt through hole penetrates through the fluid flow dividing plate; the first threaded hole corresponds to the first bolt counter bore in position, and the bolt through hole corresponds to the second bolt counter bore in position;

the upper end of the reactor main body is provided with a second threaded hole, and the second threaded hole corresponds to the position of the bolt through hole;

and integrating the reactor cover, the fluid splitter plate provided with the micro-fluid chip and the reactor body into a high-flux reactor by using bolts through the second bolt counter bore, the bolt through holes and the second threaded holes.

Further, a first sealing ring is arranged on the periphery of the cavity, and the cavity for mounting the microfluidic chip is sealed by the first sealing ring; the upper end of the reaction channel is provided with a second sealing ring, and a catalyst liner tube arranged in the reaction channel is communicated with the fluid outlet and is sealed by the second sealing ring; the periphery of the fourth fluid inlet is provided with a third sealing ring, and the fourth fluid inlet is communicated with the chip inlet and is sealed by the third sealing ring; the periphery of the fluid outlet is provided with a fourth sealing ring, and the fluid outlet is communicated with the corresponding chip outlet and is sealed through the fourth sealing ring.

Further, the depth of the cavity is not lower than the thickness of the microfluidic chip, and the shape of the cavity is adapted to the shape of the microfluidic chip.

Further, the center of the reactor cover may be provided with a gas leakage detection hole, which is connected to the detection system through a detection channel.

There is provided a high-throughput reaction system comprising at least one of the high-throughput reactors described above, further comprising:

a reactive fluid source for providing a reactive fluid;

a balance fluid source for providing a balance fluid;

a pressure controller connected to the balance fluid source through a balance common channel, the pressure controller connected to the high-throughput reactor outlet through a second fluid channel;

a switching valve through which the reaction fluid flowing out of the pressure controller enters the switching valve via a third fluid passage; the switching valve switches the reaction fluid into the collection device or the analysis system.

The beneficial effects of the invention are as follows: compared with the traditional single reactor which is complicated to assemble and disassemble and is used singly by a single tube, the technical scheme of the invention adopts a modularized design, and the reactor with a plurality of parallel channels is integrated into one module in a way of fixing the sealing ring and the flange; the catalyst is filled into the reactor main body in the form of the lining pipe, so that the loading and unloading of the catalyst are more convenient, and the disassembly of a plurality of reaction channels can be completed only by taking out the corresponding catalyst lining pipe; the temperature control mode of combining the inside and the outside is adopted, so that the internal temperature of the reaction channel is consistent.

The invention utilizes the micro-fluid chip to realize uniform distribution of fluid, adopts a temperature control mode combining inside and outside to realize accurate control of reaction temperature, and can realize simultaneous control of pressure of multiple reaction channels by a single pressure controller, and the brand new technical means are beneficial to accurately controlling the process conditions of airspeed, temperature, pressure and the like of a high-flux parallel reaction system.

Drawings

FIG. 1 is a block diagram of a high throughput reactor.

Fig. 2 is a top view of a fluid diverter plate.

Fig. 3 is a bottom view of the fluid diverter plate.

FIG. 4 is a cross-sectional view of a reactor module.

FIG. 5 is a schematic view of a heating and insulating structure wrapped outside the reactor body.

Fig. 6 is a schematic structural diagram of a microfluidic chip.

Fig. 7 is a schematic diagram of a high throughput reactor system.

Wherein: 1-a microfluidic chip; 2-high throughput reactor; 3-a pressure control module; 4-reactor cover; 5-a fluid diverter plate; 6-a reactor body; 10-a source of reactive fluid; 11-a first fluid channel; 12-chip inlet; 13-a first restricted passage; 14-a second restricted passage; 15-a third restricted passage; 16-chip outlet; 17-a pressure sensor; 18-reactor inlet; 19-a reactor; 20-catalyst bed; 21-a second fluid channel; 22-pressure controller; 23-a source of balancing fluid; 24-balancing the common channel; 25-a third fluid passage; 26-a switching valve; 27-a collection device; 28-an analysis system; 41-a first bolt counterbore; 42-a second bolt counterbore; 43-a gas leakage detection hole; 51-a first threaded hole; 52-bolt through holes; 53-a first sealing ring; 54-cavity; 61-a second threaded hole; 62-reaction channel; 63-a temperature controlled passage; 64-a second seal ring; 71-a heating layer; 72-lining layer; 73-an insulating layer; 74 an outer protective layer; 110-a chip motherboard; 111-chip sub-board; 120-fluid outlet; 121-a third fluid inlet; 122-a fourth fluid inlet; 123-a first fluid inlet; 124-a second fluid inlet; 125-a third seal ring; 126-fourth seal ring.

Detailed Description

The following description of the embodiments of the present invention is provided to facilitate understanding of the present invention by those skilled in the art, but it should be understood that the present invention is not limited to the scope of the embodiments, and all the inventions which make use of the inventive concept are protected by the spirit and scope of the present invention as defined and defined in the appended claims to those skilled in the art.

Example 1

For ease of understanding, the following technical schemes will be described in connection with the different angular views of the modules of the high-throughput reactor of fig. 1-4.

Example 1 provides a high throughput reactor 2 comprising a reactor cover 4, a fluid diverter plate 5 and a reactor body 6.

The reactor cover 4 is provided with a first bolt counter bore 41 and a second bolt counter bore 42, the first bolt counter bore 41 and the second bolt counter bore 42 are uniformly and crosswise distributed on the edge of the reactor cover 4, and the first bolt counter bore 41 and the second bolt counter bore 42 penetrate through the reactor cover 4. The center of the reactor cover 4 is provided with a gas leakage detection hole 43, and the gas leakage detection hole 43 is connected with a gas leakage detection system through a detection channel for detecting whether the microfluidic chip in the fluid splitter plate 5 is damaged or leaked.

The fluid diverter plate 5 is provided with a first threaded hole 51 and a bolt through hole 52, the first threaded hole 51 does not penetrate through the fluid diverter plate 5, the bolt through hole 52 penetrates through the fluid diverter plate 5, the first threaded hole 51 corresponds to the first bolt counter bore 41 in position, and the bolt through hole 52 corresponds to the second bolt counter bore 42 in position, as shown in the top view 2 and the bottom view 3 of the fluid diverter plate 5.

As shown in fig. 2, the middle part of the fluid diversion plate 5 is provided with a cavity 54 for placing the microfluidic chip 1. The present embodiment shows the case that the cavity 54 is square, and the shape and depth of the cavity 54 can be adjusted according to the shape and thickness of the microfluidic chip 1, so as to achieve the adaptation effect. The cavity 54 is provided with a fourth fluid inlet 122 and a groove corresponding to the third sealing ring 125, and four fluid outlets 120 and grooves corresponding to the fourth sealing ring 126 are arranged around the cavity.

As shown in fig. 3, the bottom surface of the fluid diversion plate 5 is provided with a third fluid inlet 121, the fluid outlet 120 penetrates through the fluid diversion plate 5, and the fluid diversion plate 5 is internally provided with a fluid channel penetrating through the third fluid inlet 121 and the fourth fluid inlet 122. The reactor cover 4 and the fluid diverter plate 5 are tightly combined by bolts of corresponding lengths through the first bolt counter bore 41 and the first threaded bore 51, and the cavity 54 is sealed by the first sealing ring 53, so that the reactor cover 4, the microfluidic chip 1 and the fluid diverter plate 5 form a whole, which is not disassembled any more during the catalyst loading and unloading process.

A first fluid inlet 123 is formed in the side face of the reactor main body 6, a second fluid inlet 124 is formed in the upper end of the reactor main body 6, and a fluid channel is formed in the reactor main body 6 to enable the first fluid inlet 123 and the second fluid inlet 124 to be communicated; the second fluid inlet 124 corresponds to the position of the third fluid inlet 121.

A second threaded hole 61 is formed in the upper end of the reactor main body 6, the second threaded hole 61 corresponds to the position of the bolt through hole 52, and the reactor cover 4, the fluid splitter plate 5 and the reactor main body 6 are integrated into the high-flux reactor 2 by using bolts with corresponding lengths through the second bolt counter bore 42, the bolt through hole 52 and the second threaded hole 61.

As shown in the sectional view of the reactor body 6 of fig. 4, the reactor body 6 is provided with a reaction channel 62, and a catalyst liner may be installed therein. Specifically, the reaction fluid sequentially passes through the first fluid inlet 123 and the second fluid inlet 124 in the reactor main body 6, enters the third fluid inlet 121 and the fourth fluid inlet 122 of the fluid diversion plate 5, then enters the chip inlet 12 of the microfluidic chip 1, and after being diverted by the microfluidic chip, enters the corresponding fluid outlet 120 from the chip outlet 16, and flows to the corresponding reaction channel 62. The reaction channel 62 and the fluid outlet 120 are sealed by the second sealing ring 64, the fourth fluid inlet 122 and the chip inlet 12 are sealed by the third sealing ring 125, and the chip outlet 16 and the corresponding fluid outlet 120 are sealed by the fourth sealing ring 126.

A temperature control channel 63 is also provided in the center of the reactor body 6 for mounting an internal temperature control module. In order to achieve the uniformity of the internal temperature of the reaction channel 62 and ensure the balance of the internal temperature and the external temperature, the embodiment shown in fig. 5 may further wrap the heating layer 71 on the outer wall of the reactor body 6, that is, a mode of combining the internal temperature control and the external temperature control is adopted, and an inner liner 72, an insulation layer 73 and an outer protection layer 74 are sequentially arranged outside the heating layer 71.

Compared with the traditional single reactor which is complicated to assemble and disassemble and is used singly by a single tube, the invention adopts a modularized design, and the reactor with a plurality of parallel reaction channels is integrated into a high-flux reactor in a sealing ring sealing and flange fixing mode; the catalyst is filled into the reaction sleeve in the form of the lining pipe, so that the catalyst is more convenient to assemble and disassemble, and the disassembly of the reaction channels can be completed only by taking out the corresponding reaction sleeve; the temperature control mode of combining the inside and the outside is adopted, so that the internal temperature of the reaction channel is consistent.

Example 2

As shown in fig. 6, the present embodiment provides a microfluidic chip 1 including a chip main board 110, a chip sub-board 111, a chip inlet 12, a fluid confinement channel, and a chip outlet 16.

The chip main board 110 and the chip sub-board 111 are made of a material resistant to fluid corrosion such as silicon, quartz, glass, or metal. The center of the chip motherboard 110 is coaxial with the center of the chip sub-board 111, and the length and width dimensions of the chip sub-board 111 need to cover at least all the fluid channels (including the chip inlet 12, the fluid confinement channel, and the chip outlet 16) in the chip motherboard 110. Only the chip motherboard 110 and the chip sub-board 111 are shown as square in fig. 6, it will be appreciated that the chip motherboard 110 and the chip sub-board 111 may alternatively be circular, hexagonal, or other shapes to suit specific installation and use requirements.

The chip inlet 12 is located at the center of the chip main board 110, alternatively, the chip inlet 12 may be located at the center of the chip sub-board 111. The chip inlet 12 and the chip outlet 16 are connected by a fluid-restricted channel etched into the chip motherboard 110. The fluid restriction channels may be provided with various channels on the order of microns to millimeters, depending on the various fluid flow rates, pressures, etc., and the fluid restriction channels illustrated in the example of fig. 6 may be provided with channels on the order of microns.

The fluid confining channels include a first confining channel 13, a second confining channel 14 and a third confining channel 15, which are connected in sequence to a chip inlet 12 and a chip outlet 16.

The first limiting channel 13 is provided with a plurality of alternating wide channels and narrow channels, and the two or more reaction fluids entering from the chip inlet 12 are fully mixed by continuously splitting and converging the reaction fluids.

The second limiting channel 14 is one channel or a mixture of several channels among a straight channel, a mixing channel and a unidirectional channel, so as to meet different practical application requirements.

The third limiting channel 15 is uniformly provided with a plurality of convolution cavities, each convolution cavity comprises two funnel-shaped structures connected end to end, and the one-way circulation function of each convolution cavity prevents fluid from flowing back.

In the example of fig. 6, the chip inlet 12 is connected to four fluid-confining channels, and each fluid-confining channel is connected at its end to a corresponding chip outlet 16. For example, the reaction fluid has a pressure P1 at the chip inlet 12 and a pressure P2 after entering the four fluid limiting channels to the chip outlet 16, respectively. In order to uniformly distribute the reaction fluid to the four fluid channels, that is, the differential pressures P1-P2 from the chip inlet 12 to the chip outlet 16 corresponding to the four channels are consistent, the combination mode of each fluid channel and the functions and lengths of the fluid limiting channels of each segment should be kept consistent.

Fig. 6 shows only four identical fluid-confining channels in a layout, with other combinations of fluid-confining channels and corresponding adjustments to the lengths of the individual segments of fluid-confining channels as will be apparent to those skilled in the art. Alternatively, even more fluid restriction channels 8, 12 or 16 may be laid out to meet practical application requirements.

Example 3

As shown in fig. 7, example 3 provides a high-throughput reactor system comprising a high-throughput reactor 2 and a pressure controller module 3.

The high-throughput reactor 2 comprises a microfluidic chip 1, the microfluidic chip 1 comprising a chip inlet 12, a fluid confinement channel and a chip outlet 16. The chip inlet 12 is connected to a reaction fluid source 10, and the reaction fluid source 10 is used for providing a reaction fluid, and the reaction fluid enters the chip inlet 12 from the reaction fluid source 10 through a first fluid channel 11. Wherein the reactive fluid may be at least one of a gas or a liquid. This embodiment only shows the case where the reaction fluid is split into four identical fluid limiting channels via the chip inlet 12.

The high throughput reactor 2 comprises a reactor 19, the reactor 19 being connected to a chip outlet 16, and the reaction fluid being fed into the reactor 19 via a reactor inlet 18 after exiting from the chip outlet 16. A pressure sensor 17 is arranged between the reactor inlet 18 and the chip outlet 16, the pressure sensor 17 monitors the fluid pressure P3 in real time, and the reaction fluid enters the reactor 19 and undergoes catalytic reaction in the catalyst bed 20. It should be noted that the number of reactors corresponds to the number of the above-described divided flow restricting passages, and this embodiment shows the case where four reactors are provided, but any number greater than one is possible for this embodiment.

The pressure control module 3 includes a pressure controller 22 and a balance fluid source 23. The pressure controller 22 is connected to the reactor 19 via a second fluid channel 21, and the pressure controller 22 is connected to a balancing fluid source 23 via a balancing common channel 24. The function of the pressure controller 22 is to regulate the pressure of the reaction fluid passing through the reactor 19 (i.e., the value P3 of the pressure sensor 17) to be the same as the pressure P4 of the balance fluid (p3=p4).

The high throughput reactor system of this embodiment further includes a switching valve 26, and the reaction fluid flows from the pressure controller 22, through a third fluid channel 25, and into the switching valve 26. Fig. 7 shows a case where four reaction fluids enter the switching valve 26, and the switching valve 26 employs a four-position six-way valve, and the four reaction fluids are respectively switched into the collection device 27 or the analysis system 28 by the switching valve 26.

According to the technical scheme, the micro-fluid chip 1 is utilized to realize uniform distribution of fluid, the internal and external combined temperature control mode is adopted to realize accurate control of reaction temperature, a single pressure controller is developed to realize simultaneous control of pressure of multiple reaction channels, and the brand new technical means are favorable for accurately controlling the process conditions such as airspeed, temperature, pressure and the like of a high-flux parallel reaction system.

The actual operation of the reactor module will be described specifically by taking the case that the fluid is split into four fluid limiting channels and enters into the corresponding four reaction channels 62 through the microfluidic chip 1.

TABLE 1 flow control of the channels by controlling the reactor outlet pressure at 30bar

As can be seen from the test results in Table 1, when the outlet pressure of each reaction channel 62 was regulated to 30bar by the pressure controller, the flow rates of each channel were 13.40ml/min,13.32ml/min,13.45ml/min and 13.24ml/min, respectively, and the corresponding deviations were 0.3%, -0.2%,0.7% and-0.8%, respectively, indicating that the flow rate control of each channel was relatively stable and the deviations were not large.

TABLE 2 flow control of the channels by controlling the reactor outlet pressure at 60bar

As can be seen from the test results of Table 2, when the outlet pressure of each reaction channel 62 was regulated to 30bar by the pressure controller, the flow rates of each channel were 13.34ml/min,13.25ml/min,13.16ml/min and 13.18ml/min, respectively, and the corresponding deviations were 0.8%,0.1%, 0.5% and 0.4%, respectively, indicating that the flow rate control of each channel was relatively stable and the deviations were not large.

Claims (9)

1. A high throughput reactor, comprising:

the reactor comprises a reactor main body, a plurality of reaction channels and a catalyst liner tube, wherein the reactor main body is provided with a temperature control channel, a plurality of reaction channels are arranged around the temperature control channel, and each reaction channel is internally provided with the catalyst liner tube; the side surface of the reactor main body is provided with a first fluid inlet, and the upper end of the reactor main body is provided with a second fluid inlet;

the bottom surface of the fluid flow dividing plate is provided with a third fluid inlet; the upper end of the fluid flow dividing plate is provided with a cavity for installing a micro-fluid chip, and a sealing ring groove is arranged outside the cavity; a fourth fluid inlet and a corresponding sealing ring groove are formed in the cavity; a plurality of fluid outlets and corresponding sealing ring grooves are arranged around the fourth fluid inlet, and the fluid outlets penetrate through the fluid flow dividing plate and are communicated with the upper ends of the corresponding reaction channels;

and the reactor sealing cover seals the cavity by tightly combining with a sealing ring at the periphery of the cavity.

2. The high-throughput reactor of claim 1, wherein a fluid channel is provided inside the reactor body, which communicates the first fluid inlet and the second fluid inlet; a fluid channel which penetrates through the third fluid inlet and the fourth fluid inlet is formed in the fluid flow dividing plate; the second fluid inlet corresponds to the position of the third fluid inlet.

3. The high throughput reactor of claim 1, wherein said microfluidic chip comprises:

the chip main board is provided with a chip inlet at the center, and a plurality of chip outlets are arranged around the chip inlet; the chip inlet and the chip outlet are connected through a fluid limiting channel, and the fluid limiting channel is etched in the chip main board; the chip inlet corresponds to the fourth fluid inlet, and the chip outlet corresponds to the fluid outlet;

and the center of the chip auxiliary plate is coaxial with the center of the chip main plate.

4. The high throughput reactor of claim 3, wherein the fluid confinement channel comprises at least one of a first confinement channel, a second confinement channel, and a third confinement channel;

the first limiting channel is provided with a plurality of alternating wide channels and narrow channels, and two or more than two reaction fluids entering from the chip inlet are fully mixed by continuously splitting and converging the reaction fluids;

the second limiting channel is one or a combination of a plurality of channels of a straight channel, a mixing channel and a unidirectional channel;

the third limiting channel is uniformly provided with a plurality of convolution cavities, each convolution cavity comprises two funnel-shaped structures connected end to end, and the one-way circulation function of each convolution cavity can prevent fluid from flowing back.

5. The high-throughput reactor of claim 1, wherein the reactor cover is provided with a first bolt counterbore and a second bolt counterbore, the first bolt counterbore and the second bolt counterbore are uniformly and crosswise distributed at the edge of the reactor cover, and the first bolt counterbore and the second bolt counterbore penetrate the reactor cover;

the fluid flow dividing plate is provided with a first threaded hole and a bolt through hole, the first threaded hole does not penetrate through the fluid flow dividing plate, and the bolt through hole penetrates through the fluid flow dividing plate; the first threaded hole corresponds to the first bolt counter bore in position, and the bolt through hole corresponds to the second bolt counter bore in position;

the upper end of the reactor main body is provided with a second threaded hole, and the second threaded hole corresponds to the position of the bolt through hole;

and integrating the reactor cover, the fluid splitter plate provided with the micro-fluid chip and the reactor body into a high-flux reactor by using bolts through the second bolt counter bore, the bolt through holes and the second threaded holes.

6. The high-throughput reactor of claim 1, wherein a first sealing ring is arranged at the periphery of the cavity, and the cavity for mounting the microfluidic chip is sealed by the first sealing ring; the upper end of the reaction channel is provided with a second sealing ring, and a catalyst liner tube arranged in the reaction channel is communicated with the fluid outlet and is sealed by the second sealing ring; the periphery of the fourth fluid inlet is provided with a third sealing ring, and the fourth fluid inlet is communicated with the chip inlet and is sealed by the third sealing ring; and the periphery of the fluid outlet is provided with a fourth sealing ring, and the fluid outlet is communicated with the corresponding chip outlet and is sealed by the fourth sealing ring.

7. The high throughput reactor of claim 1, wherein the depth of said cavity is no less than the thickness of the microfluidic chip, and wherein the shape of said cavity is adapted to the shape of the microfluidic chip.

8. The high throughput reactor of claim 1, wherein a center of said reactor cover is provided with a gas leakage detection aperture, said gas leakage detection aperture being connected to a detection system by a detection channel.

9. A high-throughput reaction system comprising at least one high-throughput reactor of claims 1-8, further comprising:

a reactive fluid source for providing a reactive fluid;

a balance fluid source for providing a balance fluid;

a pressure controller connected to the balance fluid source through a balance common channel, the pressure controller connected to the high-throughput reactor outlet through a second fluid channel;

a switching valve through which the reaction fluid flowing out of the pressure controller enters the switching valve via a third fluid passage; the switching valve switches the reaction fluid into the collection device or the analysis system.

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