CN116078245A

CN116078245A - Dissolution device and method of albendazole

Info

Publication number: CN116078245A
Application number: CN202211561602.5A
Authority: CN
Inventors: 孔令洋; 孟龙; 徐魁; 段苏然; 张莹; 单国庆; 韩勇
Original assignee: Jining Institute Of Food And Drug Inspection And Testing Jining Adverse Drug Reaction Monitoring Center
Current assignee: Jining Institute Of Food And Drug Inspection And Testing Jining Adverse Drug Reaction Monitoring Center
Priority date: 2022-12-07
Filing date: 2022-12-07
Publication date: 2023-05-09

Abstract

The invention discloses a dissolution device and a dissolution method of albendazole, which relate to the technical field of pharmaceutical chemistry, and have the advantages of being capable of independently stirring paddles in each dissolution cup, and the technical scheme is as follows: including the fixed plate and along the length direction interval distribution of fixed plate a plurality of boards of placing of fixed plate one side, and all place the board on all install the dissolution cup through the setting element, the fixed plate is close to one side of placing the board and is equipped with a plurality of slide that are located the dissolution cup top through moving the piece, and each slide and each place the board one-to-one, moving the piece and be used for driving each slide to be close to or keep away from the direction removal of dissolution cup, the bottom of each slide is all rotated and is connected with the stirring rake that one end stretched into in the dissolution cup, the top of each slide all is equipped with and is used for driving stirring rake pivoted first motor.

Description

Dissolution device and method of albendazole

Technical Field

The invention relates to the technical field of pharmaceutical chemistry, in particular to a dissolution device and a dissolution method of albendazole.

Background

Albendazole is a high-efficiency low-toxicity broad-spectrum insect repellent. The composition can be clinically used for expelling roundworms, pinworms, tapeworms, whipworms, hookworms, trichostrongylus, and the like. After metabolism into sulfoxides or sulfones in vivo, the parasite can be prevented from absorbing glucose, so that the glycogen of the parasite is exhausted, or the fumarate reductase system is prevented from obstructing the generation of ATP, so that the parasite can not survive and reproduce. Albendazole has been listed in the world health organization's basic drug standard list, one of the most important basic health drugs. The standard of albendazole and albendazole tablets and granules is currently received in the second edition of Chinese pharmacopoeia 2020. In general, albendazole is eluted by a paddle method (second method of the fourth rule 0931 of the chinese pharmacopoeia 2020 edition).

However, when the paddle method is used, the stirring paddles in a plurality of dissolution cups are driven to rotate simultaneously, and when the solution in one dissolution cup needs to be stirred independently, the requirement cannot be met.

Disclosure of Invention

Aiming at the technical defects, the invention aims to provide a dissolution device and a dissolution method of albendazole, which have the advantage of being capable of independently stirring paddles in each dissolution cup.

In order to solve the technical problems, the invention adopts the following technical scheme:

the invention provides an albendazole dissolving device which comprises a fixed plate and a plurality of placing plates which are distributed on one side of the fixed plate at intervals along the length direction of the fixed plate, wherein dissolving cups are arranged on the placing plates through positioning pieces, a plurality of sliding plates which are positioned above the dissolving cups are arranged on one side of the fixed plate, which is close to the placing plates, through moving pieces, the sliding plates are in one-to-one correspondence with the placing plates, the moving pieces are used for driving the sliding plates to move towards the direction, which is close to or far from the dissolving cups, the bottom ends of the sliding plates are respectively connected with stirring paddles, one ends of the stirring paddles extend into the dissolving cups, and the top ends of the sliding plates are respectively provided with a first motor for driving the stirring paddles to rotate.

Through adopting above-mentioned technical scheme, during the use, place the dissolution cup on the top of placing the board, then fix a position the dissolution cup through the setting element of placing on the board, can install the dissolution cup on placing the board this moment, then drive each slide to being close to the direction removal of dissolution cup through the moving part on the fixed plate, until in the vertical downwardly stretching into dissolution cup of rim of a cup of dissolution cup of stirring rake one end on the slide, then open the first motor on one of them slide, the axis of rotation of first motor drives the stirring rake and rotates this moment, can stir in the solitary dissolution cup, and is simple to use convenient.

Preferably, the moving part comprises a plurality of standing grooves arranged on one side of a fixed plate, and each standing groove is uniformly and fixedly connected with mounting plates between the top end and the bottom groove wall of each standing groove, each standing groove is uniformly distributed along the length direction interval of the fixed plate, one side of the fixed plate, which is close to the standing plate, is horizontally provided with two first plates, the two first plates are respectively positioned at the upper end and the lower end of each standing groove, two the horizontal sliding connection between the first plates is provided with a plurality of pushing plates, each pushing plate is uniformly and obliquely provided with pushing grooves, each pushing plate is uniformly and obliquely provided with a first groove on one side, which is close to the pushing plates, of each sliding plate, a first baffle plate is in contact with the pushing plates, each sliding plate is uniformly and fixedly connected with one side, which is close to the pushing plates, of each sliding plate is provided with a rotating shaft positioned in the pushing grooves, each rotating ring is coaxially and is in contact with the groove walls on two opposite sides of the pushing grooves, one side, which is far away from the first sliding plates is respectively, one side, which is provided with a first baffle plate is in contact with the corresponding sliding plates, and one side, which is respectively arranged between the two opposite side, and each sliding plates are respectively, and each sliding plate is in contact with the corresponding side of the first baffle plates.

Preferably, the pushing piece is including rotating the steering column of connecting in fixed plate one side right-hand member, and is equipped with first swing arm on the steering column, the one end rotation that the steering column was kept away from to first swing arm is connected with the second swing arm, the one end that first swing arm was kept away from to the second swing arm extends to between two first boards and with the push pedal of right-hand member articulated, adjacent two connect through the connecting rod between the push pedal, be equipped with the second motor that is used for driving steering column pivoted on the fixed plate.

Preferably, a second groove is formed in one side, away from the bottom of the placing groove, of each mounting plate, and the second groove is located on one side above the first groove and is communicated with the first groove.

Preferably, the one end that is close to placing the board on the fixed plate all is equipped with and is located placing the platform of board one side top, and each is placed the below that the platform all is located two first boards, each place the top of platform all and be equipped with the U-shaped bounding wall.

Preferably, the locating part is including the level seting up four spouts on placing the board top, four the spout is all along the circumference evenly distributed of dissolving out the cup, and all horizontal slip is connected with the sliding block in four spouts, four the top of sliding block is all vertical to be equipped with the locating lever that is located outside the spout, place to be equipped with on the board and be used for driving four sliding blocks simultaneously and be close to each other or the drive piece that the direction removed of keeping away from in the spout.

Preferably, the driving piece is including all the level setting in four sliding block bottoms and be located the outside driving plate of spout and set up the return shape frame of placing the board bottom, return shape frame's bottom rotation is connected with four first gears, four first gears all are along the circumference evenly distributed of dissolving out the cup, place the bottom center of board and be equipped with square plate, and square plate's bottom four corners all rotate and be connected with the second gear, adjacent two interval between the second gear is greater than the diameter of first gear, four first gear passes through the chain with the second gear and is connected, four the driving plate all is located between square plate and the inner wall of return shape frame, and four driving plate's bottom all is equipped with the vertical board that is located the chain, and one side fixed connection of vertical board and chain is equipped with on placing the board and is used for driving one of them first gear pivoted driving piece.

Preferably, the driving piece includes vertical setting at the first backup pad of placing the board bottom and coaxial center pin that sets up in one of them first gear bottom, and the bottom of center pin is equipped with the worm wheel, the bottom level of first backup pad is equipped with the second backup pad, the top of second backup pad is equipped with two relative second boards, and rotates between two second boards to be connected with the worm with worm wheel engaged with, one of them be equipped with on the second board and be used for driving worm pivoted third motor.

Preferably, one side of the four positioning rods, which is close to the dissolution cup, is provided with an arc-shaped clamping plate, and one side of the clamping plate, which is close to the dissolution cup, is provided with a rubber pad attached to the outer wall of the dissolution cup.

The invention further aims to provide a dissolution method of albendazole, when the dissolution method is used, a dissolution cup is placed at the top end of a placement plate, then the dissolution cup is positioned and fixed through a positioning piece on the placement plate, at the moment, the dissolution cup can be installed on the placement plate, then each sliding plate is driven to move towards the direction close to the dissolution cup through a moving piece on a fixed plate until one end of a stirring paddle on the sliding plate vertically extends downwards into the dissolution cup from the cup opening of the dissolution cup, then a first motor on one sliding plate is started, at the moment, the rotation shaft of the first motor drives the stirring paddle to rotate, and at the moment, the single dissolution cup can be stirred.

The invention has the beneficial effects that: when the novel water dispenser is used, the dissolving cup is placed at the top end of the placing plate, then the dissolving cup is positioned and fixed through the positioning piece on the placing plate, at the moment, the dissolving cup can be installed on the placing plate, then each sliding plate is driven to move towards the direction close to the dissolving cup through the moving piece on the fixing plate until one end of the stirring paddle on the sliding plate vertically stretches into the dissolving cup downwards from the cup opening of the dissolving cup, then the first motor on one sliding plate is opened, at the moment, the rotating shaft of the first motor drives the stirring paddle to rotate, at the moment, the single dissolving cup can be stirred, and the novel water dispenser is simple and convenient to use.

Drawings

In order to more clearly illustrate the embodiments of the invention or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the invention, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

Fig. 1 is a schematic structural view of the present embodiment;

fig. 2 is a schematic structural diagram of the first swing arm according to the present embodiment;

fig. 3 is a schematic structural diagram of the push slot according to the present embodiment;

fig. 4 is a schematic structural view of the present embodiment for embodying the second groove;

fig. 5 is a schematic view of a structure for embodying a slider of the present embodiment;

fig. 6 is a schematic structural diagram of a rectangular frame according to the present embodiment.

Reference numerals illustrate:

in the figure: 1. a fixing plate; 2. placing a plate; 3. a dissolution cup; 4. a slide plate; 5. stirring paddles; 6. a first motor; 7. a placement groove; 8. a mounting plate; 9. a first plate; 10. a push plate; 12. pushing grooves; 13. a first groove; 14. a first baffle disc; 15. a rotating shaft; 16. a swivel; 17. a slide block; 18. a second baffle disc; 19. a rotating column; 20. a first swing arm; 21. a second swing arm; 22. a connecting rod; 23. a second motor; 24. a second groove; 25. a placement table; 26. coaming plate; 27. a chute; 28. a sliding block; 29. a positioning rod; 30. a driving plate; 31. a square frame; 32. a first gear; 33. a square plate; 34. a second gear; 35. a chain; 36. a vertical plate; 37. a first support plate; 38. a central shaft; 39. a worm wheel; 40. a second support plate; 41. a second plate; 42. a worm; 43. a third motor; 44. a clamping plate; 45. and a rubber pad.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

Example 1: the utility model provides a dissolution device of albendazole, as in fig. 1, including fixed plate 1 and along the length direction interval distribution of fixed plate 1 a plurality of boards 2 of placing of fixed plate 1 one side, and each place and install dissolution cup 3 through the setting element on the board 2, one side that fixed plate 1 is close to placing the board 2 is equipped with a plurality of slide 4 that lie in dissolution cup 3 top through the moving part, and each slide 4 and each board 2 one-to-one of placing are placed, the moving part is used for driving each slide 4 to be close to or keep away from the direction removal of dissolution cup 3, the bottom of each slide 4 is all rotated and is connected with the stirring rake 5 that one end stretched into dissolution cup 3, the top of each slide 4 all is equipped with and is used for driving stirring rake 5 pivoted first motor 6.

When the novel water dispenser is used, as shown in fig. 1, the dissolving cup 3 is placed at the top end of the placing plate 2, then the dissolving cup 3 is positioned and fixed through the positioning piece on the placing plate 2, the dissolving cup 3 can be installed on the placing plate 2 at the moment, then each sliding plate 4 is driven to move towards the direction close to the dissolving cup 3 through the moving piece on the fixing plate 1 until one end of the stirring paddle 5 on the sliding plate 4 vertically stretches into the dissolving cup 3 downwards from the cup opening of the dissolving cup 3, then the first motor 6 on one sliding plate 4 is opened, at the moment, the rotating shaft of the first motor 6 drives the stirring paddle 5 to rotate, and at the moment, the novel water dispenser can be used for stirring in the independent dissolving cup 3, and is simple and convenient to use.

As shown in fig. 1, 2 and 3, the moving member comprises a plurality of placing grooves 7 arranged on one side of a fixed plate 1, wherein mounting plates 8 are fixedly connected between the groove walls at the top end and the bottom end of each placing groove 7, each placing groove 7 is distributed at intervals along the length direction of the fixed plate 1, one side of the fixed plate 1 close to the placing plate 2 is horizontally provided with two first plates 9, the two first plates 9 are respectively positioned at the upper end and the lower end of each placing groove 7, a plurality of pushing plates 10 are horizontally and slidingly connected between the two first plates 9, each pushing plate 10 is in one-to-one correspondence with each mounting plate 8, pushing grooves 12 are obliquely arranged on one side of each pushing plate 10 away from the mounting plate 8, first grooves 13 are vertically arranged on one side of each mounting plate 8 close to the pushing plate 10, each sliding plate 4 is in one-to-one correspondence with each pushing plate 10, one side of each sliding plate 4 close to the pushing plate 10 is provided with first baffle plates 14 contacted with the pushing plates 10, each first baffle disc 14 is equipped with the pivot 15 that is located pushing away from the one end of slide 4 in groove 12, and all coaxial rotation is connected with swivel 16 in the pivot 15, the outer wall of each swivel 16 and the cell wall contact of pushing away the opposite both sides of groove 12, each pivot 15 is equipped with the square slider 17 that is located first inslot 13 that deviates from first baffle disc 14, and the opposite both sides of slider 17 all contact with the cell wall of first inslot 13, each slider 17 deviates from the one side of pivot 15 all is equipped with the second baffle disc 18 that is located outside first inslot 13, each second baffle disc 18 all is located between mounting panel 8 and the tank bottom of standing groove 7, and one side that second baffle disc 18 is close to mounting panel 8 all contacts with mounting panel 8, be equipped with on the fixed plate 1 and be used for promoting each push pedal 10 horizontal slip's between two first boards 9 simultaneously.

As shown in fig. 1, 2 and 3, when it is required to drive each slide plate 4 to move in a direction approaching to the dissolution cup 3, so that one end of the stirring paddle 5 extends vertically downward into the dissolution cup 3 from the cup mouth of the dissolution cup 3, each push plate 10 is pushed to slide horizontally between the two first plates 9 only by the pushing member, at this time, because the first baffle plate 14 on the slide plate 4 contacts with the push plate 10, the rotating shaft 15 on the first baffle plate 14 is located in the push groove 12, the outer wall of the rotating ring 16 on the rotating shaft 15 contacts with the groove walls on opposite sides of the push groove 12, the opposite sides of the sliding block 17 on the rotating shaft 15 contact with the groove walls of the first groove 13, the second baffle plate 18 on the sliding block 17 is located outside the first groove 13 and contacts with the mounting plate 8, so when each push plate 10 is pushed to slide horizontally between the two first plates 9 by the pushing member, the cooperation of each swivel 16 and each rotating shaft 15 with each pushing groove 12 can drive each sliding block 17 to vertically move up and down in the first groove 13, each sliding plate 4 to vertically move up and down, when the pushing piece simultaneously pushes each pushing plate 10 to horizontally slide leftwards between the two first plates 9, the sliding blocks 17 and the sliding plates 4 vertically move downwards to be close to the dissolution cup 3, at the moment, one end of the stirring paddle 5 vertically stretches into the dissolution cup 3 downwards from the cup mouth of the dissolution cup 3, after the stirring paddle 5 completes stirring the dissolution cup 3, each pushing plate 10 is simultaneously pushed to horizontally slide rightwards between the two first plates 9 by the pushing piece, and at the moment, the sliding blocks 17 and the sliding plates 4 vertically move upwards to be away from the dissolution cup 3 until one end of the stirring paddle 5 moves out of the dissolution cup 3, and the stirring paddle is simple and convenient to use.

As shown in fig. 1 and 2, the pushing member comprises a rotary column 19 rotatably connected to the right end of one side of a fixed plate 1, a first swing arm 20 is arranged on the rotary column 19, one end of the first swing arm 20 away from the rotary column 19 is rotatably connected with a second swing arm 21, one end of the second swing arm 21 away from the first swing arm 20 extends between two first plates 9 and is hinged with a rightmost push plate 10, two adjacent push plates 10 are connected through a connecting rod 22, a second motor 23 for driving the rotary column 19 to rotate is arranged on the fixed plate 1, the purpose of the arrangement is that when each push plate 10 needs to be pushed to slide horizontally between the two first plates 9 at the same time, only the second motor 23 is required to be turned on, at the moment, the rotary shaft of the second motor 23 drives the rotary column 19 to rotate, the rotary column 19 drives the first swing arm 20 to rotate along the rotation axis of the rotary column 19, at this time, the first swing arm 20 rotating along the rotation axis of the rotary column 19 is matched with the rightmost push plate 10 and the connecting rod 22 between the two adjacent push plates 10, so that each push plate 10 can be pushed to slide horizontally back and forth between the two first plates 9, when each push plate 10 slides horizontally leftwards between the two first plates 9, one end of the stirring paddle 5 vertically stretches downwards into the dissolution cup 3 from the cup opening of the dissolution cup 3, the second motor 23 stops working, at this time, the first swing arm 20 is positioned at one side of the rotary column 19, deviating from the push plate 10, after the stirring paddle 5 completes stirring in the dissolution cup 3, the second motor 23 starts working, each push plate 10 is pushed to slide horizontally rightwards between the two first plates 9 through the rotary column 19, the first swing arm 20 and the second swing arm 21, so that the stirring paddle 5 moves out of the dissolution cup 3, and the rotary shaft of the second motor 23 always drives the rotary column 19 to rotate clockwise, and the use is simple and convenient.

As shown in fig. 1, fig. 3 and fig. 4, the second groove 24 is formed on the side of each mounting plate 8 facing away from the bottom of the placement groove 7, and the second groove 24 is located on the upper side of the first groove 13 and is communicated with the first groove 13, the purpose of this arrangement is that when each push plate 10 is pushed to slide horizontally rightward between the two first plates 9 by the pushing member, at this moment, the slide block 17 and the slide plate 4 move vertically upwards away from the dissolution cup 3 until one end of the stirring paddle 5 moves out of the dissolution cup 3, after that, the pushing member continues to push each push plate 10 to slide horizontally rightward between the two first plates 9, at this moment, the slide block 17 enters the second groove 24 from the first groove 13, when the slide block 17 enters the second groove 24 from the first groove 13, the outer wall of the rotating ring 16 pushes the top groove wall of the groove 12 to contact, at this moment, along with the horizontal rightward sliding of the push plate 10, the push groove 12 drives the slide block 17, the slide plate 4, the first baffle plate 14, the second baffle plate 18 and the stirring paddle 5 after the removal of the dissolution cup 3 move horizontally along the length direction of the second groove 24 to move horizontally away from the dissolution cup 3, at this moment, the stirring paddle 5 moves horizontally away from the dissolution cup 3, at this moment, and the side of the dissolution cup 3 is reduced, and the situation can be easily removed, and the stirring cup can be easily and the situation can be removed.

Like fig. 1, the one end that is close to placing board 2 on fixed plate 1 all is equipped with and is located placing the platform 25 of placing board 2 one side top, and each place the platform 25 and all be located the below of two first boards 9, the top of each platform 25 all is equipped with U-shaped bounding wall 26, the purpose of this setting is that when will shift out the stirring rake 5 after dissolving out the cup 3 along the length direction level of second groove 24 to the direction of keeping away from dissolving out the cup 3, until when removing stirring rake 5 to the top one side of dissolving out the cup 3, stirring rake 5 is located the bounding wall 26 of placing on the platform 25, can protect stirring rake 5 through bounding wall 26 this moment, reduce the condition emergence of mistake touch stirring rake 5 again, easy to use is convenient.

As shown in fig. 1, fig. 5 and fig. 6, the setting element includes four spouts 27 that the level was offered on the top of placing the board 2, four spouts 27 all are along the circumference evenly distributed of dissolving out cup 3, and all level slip in four spouts 27 is connected with sliding block 28, the top of four sliding block 28 all is vertical to be equipped with the locating lever 29 that is located outside spout 27, be equipped with on placing the board 2 and be used for driving the driving element that four sliding block 28 moved to the direction that is close to each other or keep away from each other in spout 27 simultaneously, this setting aim at places dissolving out cup 3 between four locating levers 29, then drive four sliding block 28 simultaneously through the driving element and move to the direction that is close to each other in spout 27, four locating levers 29 are close to each other this moment, until outer wall one side of four locating levers 29 all supports with the outer wall of dissolving out cup 3 tightly, can fix a position dissolving out cup 3 this moment, reduce when stirring rake 5 rotates, the condition that dissolving out cup 3 takes place the displacement, and is simple to use.

As shown in fig. 5 and 6, the driver includes the equal level setting in four sliding block 28 bottoms and is located the outside drive board 30 of spout 27 and set up the back form frame 31 of placing the board 2 bottom, the bottom rotation of back form frame 31 is connected with four first gears 32, four first gears 32 are all along dissolving out the circumference evenly distributed of cup 3, the bottom center of placing board 2 is equipped with square plate 33, and the bottom four corners of square plate 33 all rotates and is connected with second gear 34, interval between two adjacent second gears 34 is greater than the diameter of first gear 32, four first gears 32 and second gear 34 pass through chain 35 and are connected, four drive board 30 all is located between square plate 33 and the inner wall of back form frame 31, and the bottom of four drive board 30 all is equipped with the vertical board 36 that is located chain 35, and one side fixed connection of vertical board 36 and chain 35, be equipped with the driver that is used for driving one of them first gears 32 pivoted on placing the board 2 this occasion, the purpose that this setting lies in when needs four sliding block 28 to move in the direction of spout 27 each other simultaneously, the distance between two second gears 34 is greater than the diameter of first gear 32, four first gears 32 just need be driven by one of the first gears 32 through the fourth gears 35 and then drive board 32 through four gears 35 and can make one of the four gears 32 rotate simultaneously and drive the fourth gears 32 and the fourth gear 35 and can be driven by one of the four drive board 32 through the fourth gears 35 and the four drive board 30 and the side 35 and the side.

As shown in fig. 6, the driving member includes a first supporting plate 37 vertically disposed at the bottom end of the placement plate 2 and a central shaft 38 coaxially disposed at the bottom end of one of the first gears 32, and the bottom end of the central shaft 38 is provided with a worm gear 39, the bottom end of the first supporting plate 37 is horizontally provided with a second supporting plate 40, the top end of the second supporting plate 40 is provided with two opposite second plates 41, a worm 42 meshed with the worm gear 39 is rotatably connected between the two second plates 41, and a third motor 43 for driving the worm 42 to rotate is disposed on one of the second plates 41.

If 51, four locating lever 29 are close to the one side that dissolves out cup 3 and all are equipped with arc splint 44, and splint 44 are close to the one side that dissolves out cup 3 be equipped with dissolve out the rubber pad 45 of cup 3 outer wall laminating, the purpose that this set up can increase the area of contact of locating lever 29 and dissolving out cup 3 through splint 44, rubber pad 45, can protect dissolving out cup 3 simultaneously through rubber pad 45, when reducing fixed dissolving out cup 3 of location, the wearing and tearing that splint 44 caused the dissolving out cup 3 outer wall, and is simple to use is convenient.

Example 2: a dissolution method of albendazole comprises the above embodiment 1, when in use, a dissolution cup 3 is placed at the top end of a placement plate 2, then the dissolution cup 3 is positioned and fixed by a positioning piece on the placement plate 2, at the moment, the dissolution cup 3 can be installed on the placement plate 2, then each sliding plate 4 is driven to move towards the direction close to the dissolution cup 3 by a moving piece on the fixing plate 1 until one end of a stirring paddle 5 on the sliding plate 4 vertically extends downwards into the dissolution cup 3 from the cup opening of the dissolution cup 3, then a first motor 6 on one sliding plate 4 is opened, at the moment, the rotation shaft of the first motor 6 drives the stirring paddle 5 to rotate, at the moment, the single dissolution cup 3 can be stirred, and the use is simple and convenient.

It will be apparent to those skilled in the art that various modifications and variations can be made to the present invention without departing from the spirit or scope of the invention. Thus, it is intended that the present invention also include such modifications and alterations insofar as they come within the scope of the appended claims or the equivalents thereof.

Claims

1. The utility model provides a dissolution device of albendazole, its characterized in that, including fixed plate (1) and along a plurality of boards (2) of placing of length direction interval distribution in fixed plate (1) one side of fixed plate (1), and each place on board (2) and all install dissolution cup (3) through the setting element, one side that fixed plate (1) is close to placing board (2) is equipped with a plurality of slide (4) that lie in dissolution cup (3) top through the moving part, and each slide (4) and each board (2) of placing one-to-one, and the moving part is used for driving each slide (4) to be close to or keep away from the direction removal of dissolution cup (3), each the bottom of slide (4) is all rotated and is connected with stirring rake (5) that one end stretched into in dissolution cup (3), and each the top of slide (4) all is equipped with and is used for driving stirring rake (5) pivoted first motor (6).

2. The albendazole leaching device of claim 1, wherein the moving member comprises a plurality of placing grooves (7) arranged on one side of the fixed plate (1), wherein mounting plates (8) are fixedly connected between the top end groove walls and the bottom end groove walls of the placing grooves (7), the placing grooves (7) are distributed at intervals along the length direction of the fixed plate (1), two first plates (9) are horizontally arranged on one side of the fixed plate (1) close to the placing plate (2), the two first plates (9) are respectively arranged at the upper end and the lower end of each placing groove (7), a plurality of pushing plates (10) are horizontally connected between the two first plates (9) in a sliding manner, each pushing plate (10) is in one-to-one correspondence with each mounting plate (8), pushing grooves (12) are obliquely arranged on one side of each pushing plate (10) away from the mounting plate (8), first grooves (13) are vertically arranged on one side of each mounting plate (8) close to the pushing plate (10), each pushing plate (4) is in one-to-one correspondence with each pushing plate (10), a retaining plate (14) is arranged on one side of each pushing plate (4) close to the pushing plate (10), each retaining plate (14) is in one side of the pushing plate (14) away from the pushing plate (14), and all coaxial rotation is connected with swivel (16) on pivot (15), each the outer wall of swivel (16) and the cell wall contact of pushing away the relative both sides of groove (12), each one side that pivot (15) deviate from first fender dish (14) all is equipped with square slider (17) that are located in first groove (13), and the relative both sides of slider (17) all with the cell wall contact of first groove (13), each one side that slider (17) deviate from pivot (15) all is equipped with second fender dish (18) that are located outside first groove (13), each second fender dish (18) all is located between the tank bottom of mounting panel (8) and standing groove (7), and one side that second fender dish (18) is close to mounting panel (8) all contacts with mounting panel (8), be equipped with on fixed plate (1) and be used for promoting each push pedal (10) simultaneously horizontal slip's promotion piece between two first boards (9).

3. The albendazole leaching device according to claim 2, wherein the pushing member comprises a rotating column (19) rotatably connected to the right end of one side of the fixed plate (1), a first swing arm (20) is arranged on the rotating column (19), one end of the first swing arm (20), which is far away from the rotating column (19), is rotatably connected with a second swing arm (21), one end of the second swing arm (21), which is far away from the first swing arm (20), extends between the two first plates (9) and is hinged with the rightmost push plate (10), two adjacent push plates (10) are connected through a connecting rod (22), and a second motor (23) for driving the rotating column (19) to rotate is arranged on the fixed plate (1).

4. The albendazole leaching device according to claim 2, wherein the side of each mounting plate (8) facing away from the bottom of the holding tank (7) is provided with a second tank (24), and the second tank (24) is located on the upper side of the first tank (13) and is communicated with the first tank (13).

5. The albendazole leaching device according to claim 4, wherein the fixed plate (1) is provided with a placing table (25) at one end close to the placing plate (2) and above one side of the placing plate (2), each placing table (25) is located below two first plates (9), and the top end of each placing table (25) is provided with a U-shaped coaming (26).

6. The albendazole dissolving device according to claim 1, wherein the positioning member comprises four sliding grooves (27) horizontally arranged at the top end of the placing plate (2), the four sliding grooves (27) are uniformly distributed along the circumferential direction of the dissolving cup (3), sliding blocks (28) are horizontally and slidingly connected in the four sliding grooves (27), positioning rods (29) positioned outside the sliding grooves (27) are vertically arranged at the top ends of the four sliding blocks (28), and the placing plate (2) is provided with a driving member for simultaneously driving the four sliding blocks (28) to move in the direction of approaching or separating from each other in the sliding grooves (27).

7. The albendazole dissolving device according to claim 1, wherein the driving element comprises driving plates (30) which are horizontally arranged at the bottom ends of four sliding blocks (28) and are positioned outside the sliding groove (27) and a square frame (31) which is arranged at the bottom end of the placing plate (2), the bottom ends of the square frame (31) are rotationally connected with four first gears (32), the four first gears (32) are uniformly distributed along the circumference of the dissolving cup (3), the bottom end center of the placing plate (2) is provided with a square plate (33), the four corners of the bottom end of the square plate (33) are rotationally connected with second gears (34), the distance between every two adjacent second gears (34) is larger than the diameter of the first gear (32), the four first gears (32) are connected with the second gears (34) through chains (35), the four driving plates (30) are located between the square plate (33) and the inner wall of the square frame (31), the bottom ends of the four driving plates (30) are provided with a vertical driving plate (36), and the bottom ends of the four driving plates (30) are provided with a vertical driving plate (36) and are fixedly arranged on one side of the driving plate (32).

8. The albendazole leaching device according to claim 7, wherein the driving member comprises a first supporting plate (37) vertically arranged at the bottom end of the placing plate (2) and a central shaft (38) coaxially arranged at the bottom end of one of the first gears (32), a worm wheel (39) is arranged at the bottom end of the central shaft (38), a second supporting plate (40) is horizontally arranged at the bottom end of the first supporting plate (37), two opposite second plates (41) are arranged at the top end of the second supporting plate (40), a worm (42) meshed with the worm wheel (39) is rotatably connected between the two second plates (41), and a third motor (43) for driving the worm (42) to rotate is arranged on one of the second plates (41).

9. The albendazole leaching device according to claim 6, wherein the four positioning rods (29) are provided with arc-shaped clamping plates (44) on one side close to the leaching cup (3), and rubber pads (45) attached to the outer wall of the leaching cup (3) are arranged on one side of the clamping plates (44) close to the leaching cup (3).

10. A method of an albendazole eluting device according to any one of the claims 1-9, characterized in that, in use, the eluting cup (3) is placed on the top end of the placing plate (2), then the eluting cup (3) is fixed by positioning members on the placing plate (2), at this time, the eluting cup (3) is mounted on the placing plate (2), then each slide plate (4) is driven by moving members on the fixing plate (1) to move in a direction close to the eluting cup (3) until one end of a stirring paddle (5) on the slide plate (4) vertically extends downwards into the eluting cup (3) from the cup opening of the eluting cup (3), then a first motor (6) on one of the slide plates (4) is opened, at this time, the rotation shaft of the first motor (6) drives the stirring paddles (5) to rotate, and at this time, the inside of the individual eluting cup (3) can be stirred.