CN116046216A - Temperature sensor calibration auxiliary device and application method thereof - Google Patents

Abstract

The invention relates to the technical field of sensor calibration, and discloses a temperature sensor calibration auxiliary device, which comprises a sensor mounting pipe, wherein two ends of the sensor mounting pipe are connected into a medium circulation pipeline, the medium circulation pipeline is filled with a heat-conducting medium, and the temperature of the heat-conducting medium can be changed and can be kept in preset different constant temperature states; the reference temperature sensor is configured to be detected to be qualified by the third-party detection mechanism, and the detection end of the reference temperature sensor stretches into the heat conducting medium to detect a reference temperature value of the heat conducting medium; the outside of the sensor installation tube is provided with a plurality of connecting seats for installing temperature sensors to be detected, the temperature sensors to be detected are detachably connected with the connecting seats, and the detection ends of the temperature sensors to be detected extend into the sensor installation tube to detect the temperature of the heat-conducting medium and obtain detection values. The invention has the beneficial effects of convenient use and capability of carrying out batch auxiliary calibration on the temperature sensor.

Description

Temperature sensor calibration auxiliary device and application method thereof

Technical Field

The invention relates to the technical field of sensor calibration, in particular to a temperature sensor calibration auxiliary device and a use method thereof.

Background

In the field of biopharmaceutical devices, almost all devices are involved in temperature control, which plays a critical role in the production process of the production device. Accurate temperature measurement is the most important and fundamental function in biopharmaceutical devices. To ensure accuracy of the measured temperature, the temperature sensor in the biopharmaceutical device needs to be checked periodically, and if necessary, calibrated, and two of the most commonly used temperature values in the biopharmaceutical device are 37 ℃, which is the optimal temperature for bacteria and cell culture, and 121 ℃, which is the optimal temperature for sterilization. The calibrating equipment commonly used at present adopts the constant temperature tank generally, and the constant temperature range of constant temperature tank is very wide, but this kind of calibrating equipment is with high costs, and convenient to use moreover, can only calibrate single temperature sensor at a time, and has a plurality of temperature sensors in a bio-pharmaceuticals equipment generally, and calibration efficiency is low.

Disclosure of Invention

The invention aims to solve the problems in the prior art, and provides a temperature sensor calibration auxiliary device which is convenient to use and can perform batch auxiliary calibration on a temperature sensor and a use method thereof.

In order to achieve the above purpose, the present invention adopts the following technical scheme:

a temperature sensor calibration auxiliary device includes

The sensor installation tube, two ends of the sensor installation tube are connected into a medium circulation pipeline, the medium circulation pipeline is filled with a heat-conducting medium, and the temperature of the heat-conducting medium can be changed and can be kept in different preset constant temperature states; and

the reference temperature sensor is configured to be detected to be qualified by a third-party detection mechanism, and the detection end of the reference temperature sensor stretches into the heat conducting medium to detect a reference temperature value of the heat conducting medium;

the sensor mounting tube is characterized in that a plurality of connecting seats for mounting temperature sensors to be measured are arranged on the outer side of the sensor mounting tube, the temperature sensors to be measured are detachably connected with the connecting seats, and the detection ends of the temperature sensors to be measured extend into the sensor mounting tube to detect the temperature of the heat-conducting medium and obtain detection values.

And installing the temperature sensor to be calibrated on the connecting seat, installing the reference temperature sensor in the medium circulation pipeline for detecting the temperature of the medium, further obtaining a reference temperature value, keeping the temperature of the heat conducting medium at the reference temperature value, observing the detection value of the temperature sensor to be calibrated, and finally calibrating the detection value to be the reference temperature value. The calibration auxiliary equipment provides a temperature reference for the temperature sensors to be measured, the calibration standard of the temperature sensors to be measured is to calibrate the sensors to be measured through a calibration module in the biopharmaceutical equipment, and the calibration auxiliary equipment is characterized by being convenient to use, and capable of providing the temperature reference for a plurality of temperature sensors to be measured at the same time, so that the calibration efficiency of the temperature sensors is improved.

Preferably, an electric heater for heating the heat-conducting medium and a circulating pump for driving the heat-conducting medium to circularly flow are arranged in the medium circulating pipeline; the lower extreme of medium circulation pipeline is equipped with the feed liquor pipe, has the drain pipe on the feed liquor pipe in parallel, the junction of feed liquor pipe and drain pipe is equipped with the relief valve group that is arranged in controlling the heat conduction medium pressure in the medium circulation pipeline, be equipped with the back flow between the upper end of medium circulation pipeline and the drain pipe, be equipped with the automatically controlled valve on the back flow. The return pipe can discharge air in the medium circulation pipeline when the heat conducting medium enters the medium circulation pipeline, so that the influence of residual air in the medium circulation pipeline on the temperature is prevented.

Preferably, the heat-conducting medium adopts cooling water with an initial temperature of 5-30 ℃, the working pressure of the heat-conducting medium in the medium circulation pipeline is 2.5-3.5Bar, and when the working pressure of the heat-conducting medium is more than 3.5Bar, the safety valve group automatically discharges liquid and releases pressure. Directly adopts water as a heat conducting medium, has low cost and little pollution (when tap water at normal temperature meets the temperature range, tap water can be directly adopted); the pressure of the heat conducting medium is controlled to increase the boiling point of water, so that the water can be heated to 125 ℃ to meet the calibration requirement of a temperature sensor in the biopharmaceutical field; the temperature of the cooling water is raised by the electric heater, when the cooling water (heated) needs to be cooled, the electric control valve is only required to be opened, so that the cooling water with the initial temperature in the liquid inlet pipe enters the medium circulation pipeline, and meanwhile, the heated cooling water is discharged from the electric control valve, so that the heat conducting medium (water) in the medium circulation pipeline can be cooled.

Preferably, the two ends of the sensor mounting pipe are respectively provided with a pipe joint, the inner ends of the pipe joints are fixedly connected with the sensor mounting pipe, and the lower ends of the pipe joints are connected with the medium circulation pipeline through a clamp. The two ends of the sensor mounting tube are connected with the medium circulation pipeline through the pipe joint through the clamp, and the sensor mounting tube is very convenient to mount and dismount.

Preferably, the upper end of one pipe joint extends to form an upper channel, an upper clamp seat is arranged at the upper end of the upper channel, a connecting sleeve is fixedly arranged at the upper end of the reference temperature sensor, a lower clamp seat is arranged at the lower end of the connecting sleeve, the detection end of the reference temperature sensor is axially inserted into a medium circulation pipeline from top to bottom in the upper channel, and the upper clamp seat is connected with the lower clamp seat through a clamp; the upper end of the other pipe joint is communicated with the upper end of the return pipe. The detection end of the reference temperature sensor is directly inserted into the central position of the medium circulation pipeline, so that a very accurate reference temperature value can be obtained; in addition, in order to ensure the precision of the whole calibration auxiliary device, regular sending inspection is needed, and the reference temperature sensor is directly connected through the clamp, so that the disassembly is very convenient, and the reference temperature sensor is only required to be directly disassembled independently for the sending inspection by a third party, and the whole device is not required to be moved for the sending inspection.

Preferably, the sensor mounting pipe is of a U-shaped structure, the plane formed by the sensor mounting pipe is horizontally distributed and arranged at the upper end of the medium circulation pipeline, the outer end of the connecting seat is provided with a chuck interface, and the temperature sensor to be detected is connected with the chuck interface through a clamp. The temperature sensor to be measured is very convenient to install and detach from the connecting seat.

Preferably, the connecting seats are alternately distributed on two sides of the sensor mounting tube, the axis of the connecting seat penetrates through the axis of the sensor mounting tube, the outer ends of the connecting seats are obliquely distributed upwards, and an included angle of 45-60 degrees is formed between the axis of the connecting seat and the horizontal plane. The detection ends of the temperature sensors to be detected extend into the sensor mounting pipes and are connected with the connecting seats, at the moment, along the axial direction of the sensor mounting pipes, two adjacent temperature sensors to be detected are distributed in a staggered mode (not on the same phase), so that when a heat conducting medium flows in the sensor mounting pipes, the temperature of the heat conducting medium part tends to be more uniform, and errors caused by local difference of the temperature of the heat conducting medium are reduced.

Preferably, the inner end of the connecting seat extends towards the inner center of the sensor mounting tube to form a closed heat conduction isolation sleeve, the heat conduction isolation sleeve completely isolates a heat conduction medium from the inner space of the connecting seat, and heat conduction silicone oil is filled in the heat conduction isolation sleeve; the outer wall of the heat conduction isolation sleeve is provided with a plurality of annular grooves. The heat-conducting isolation sleeve enables the inside and outside of the connecting seat to be completely isolated, so that the sensor to be detected is isolated from the heat-conducting medium, the pressure of the heat-conducting medium is prevented from acting on the temperature sensor to be detected, the heat of the heat-conducting medium is transmitted to the heat-conducting silicone oil, the temperature of the heat-conducting silicone oil is the same as that of the heat-conducting medium, and finally the temperature value of the heat-conducting silicone oil detected by the temperature sensor to be detected is the temperature value of the heat-conducting medium; the annular groove effectively increases the heat conduction area.

Preferably, the device also comprises a frame and a controller arranged on the frame and used for adjusting the medium temperature in the medium circulation pipeline, wherein the electric heater, the circulating pump and the electric control valve are all connected with the controller; the bottom of the frame is provided with a roller which is convenient to move.

A method of using a temperature sensor calibration device, comprising the steps of:

s1, installing a standard temperature sensor which is detected to be qualified by a third-party detection mechanism in a medium circulation pipeline, detaching the temperature sensor to be detected from other biopharmaceutical equipment and installing the temperature sensor to be detected on a connecting seat, wherein the temperature sensor to be detected is still connected with the biopharmaceutical equipment through a data line;

s2, opening an electric control valve on the return pipe, feeding heat-conducting medium into a medium circulation pipeline from a liquid inlet pipe, closing the electric control valve after air in the medium circulation pipeline is completely discharged from the return pipe, and closing a safety valve group when the pressure in the medium circulation pipeline reaches a preset value, wherein the whole medium circulation pipeline forms a closed loop;

s3, starting a circulating pump, heating a heat-conducting medium through an electric heater, and when the detection value of a reference temperature sensor reaches a preset temperature value t1, feeding back and adjusting the heat-conducting medium in a medium circulating pipeline by a controller according to the value of t1, so that the heat-conducting medium is in a stable constant-temperature state at t1, wherein t1 is the reference temperature value;

s4, obtaining a detection value T1 of a corresponding temperature sensor to be detected from the biopharmaceutical equipment, if the detection value T1 is equal to a reference temperature value T1 or the error is within an allowable range, calibrating the temperature sensor to be detected is not needed, and if the error of the detection value T1 and the reference temperature value T1 is beyond the allowable range, calibrating the temperature sensor to be detected on the biopharmaceutical equipment directly, so that the detection value T1 is equal to the reference temperature value T1;

s5, repeating the steps S3 and S4 for a plurality of times to obtain detection values T2 and T3 … … Tn of corresponding temperature sensors to be detected under the condition of reference temperature values T2 and T3 … … Tn, comparing the detection values Tn with the reference temperature values Tn, and calibrating the corresponding temperature sensors to be detected according to the method in the step S4;

s6, after the temperature sensor to be measured is calibrated, the temperature sensor to be measured is removed from the connecting seat, cleaned and then installed in corresponding biopharmaceutical equipment.

Therefore, the invention is convenient to use, can simultaneously install a plurality of temperature sensors to be measured, and provides reference temperature for the temperature sensors to be measured; the reference temperature sensor is convenient to disassemble and assemble and can be independently sent for inspection; the water is used as a circulating heat conducting medium, so that the overall cost is low and the pollution is small; the heat conduction isolation sleeve is arranged to separate the sensor to be detected from water, so that the temperature sensor to be detected can be protected, and leakage at the joint can be prevented.

Drawings

Fig. 1 is a schematic diagram of the overall structure of the present invention.

Fig. 2 is a schematic view of a sensor mounting tube connected to a medium circulation line.

FIG. 3 is a schematic diagram of the connection of a temperature sensor to be measured to a sensor mounting tube.

Fig. 4 is a front view of fig. 3.

FIG. 5 is a cross-sectional view taken at A-A of FIG. 4.

Fig. 6 is a cross-sectional view at B-B in fig. 4.

In the figure: sensor installation tube 1, connecting seat 10, chuck interface 100, heat conduction isolation sleeve 101, heat conduction silicone oil 102, ring channel 103, medium circulation pipeline 2, feed liquor pipe 20, drain pipe 21, relief valve group 22, back flow 23, automatically controlled valve 24, heat conduction medium 3, benchmark temperature sensor 4, adapter sleeve 40, lower clamp seat 41, temperature sensor 5, electric heater 6, circulating pump 7, frame 8, gyro wheel 80, controller 9, coupling 11, upper passageway 110, upper clamp seat 111, clamp 12.

Detailed Description

In order to make the technical problems, technical solutions and advantageous technical effects to be solved by the present invention more apparent, the present invention will be further described in detail with reference to the accompanying drawings and a plurality of exemplary embodiments. It should be understood that the detailed description and specific examples are intended for purposes of illustration only and are not intended to limit the scope of the invention.

It should be appreciated that the expressions "first", "second", etc. are used herein for descriptive purposes only and are not to be construed as indicating or implying relative importance or as implying any particular order of number of technical features indicated. Features defining "first", "second" or "first" may be expressed or implied as including at least one such feature.

The temperature sensor calibration auxiliary device as shown in fig. 1-6 comprises a sensor mounting tube 1, wherein two ends of the sensor mounting tube are connected into a medium circulation pipeline 2, the medium circulation pipeline is filled with a heat conducting medium 3, and the temperature of the heat conducting medium 3 can be changed and can be kept in preset different constant temperature states; and a reference temperature sensor 4, the reference temperature sensor 4 being configured to have been detected as being qualified by the third party detecting means, a detection end of the reference temperature sensor 4 extending into the heat-conducting medium for detecting a reference temperature value of the heat-conducting medium; the outside of the sensor installation tube 1 is provided with a plurality of connecting seats 10 for installing the temperature sensor 5 to be detected, the temperature sensor 5 to be detected is detachably connected with the connecting seats, and the detection end of the temperature sensor 5 to be detected stretches into the sensor installation tube 1 to detect the temperature of the heat conducting medium and obtain a detection value.

An electric heater 6 for heating the heat-conducting medium and a circulating pump 7 for driving the heat-conducting medium to circularly flow are arranged in the medium circulating pipeline 2; the lower extreme of medium circulation pipeline 2 is equipped with feed liquor pipe 20, connects in parallel on the feed liquor pipe has drain pipe 21, and the junction of feed liquor pipe and drain pipe is equipped with the relief valve group 22 that is arranged in controlling the heat conduction medium pressure in the medium circulation pipeline, is equipped with back flow 23 between the upper end of medium circulation pipeline and the drain pipe, is equipped with automatically controlled valve 24 on the back flow. The medium circulation pipeline 2 in the embodiment is arranged on the frame 8, the frame 8 is provided with a controller 9 for adjusting the medium temperature in the medium circulation pipeline, the electric heater 6, the circulation pump 7 and the electric control valve 24 are all connected with the controller, and the bottom of the frame is provided with a roller 80 which is convenient to move. The return pipe is used for evacuating air in the medium circulation pipeline in the initial stage, and the electric control valve is closed after the air is exhausted.

The heat conducting medium 3 adopts cooling water with the initial temperature of 5-30 ℃, the working pressure of the heat conducting medium in a medium circulation pipeline is 2.5-3.5Bar, and when the working pressure of the heat conducting medium is more than 3.5Bar, the safety valve group automatically discharges liquid and releases pressure. In general, the cooling water directly adopts tap water in a room temperature state, and if the initial temperature of the tap water exceeds the requirement, the tap water is cooled by a cooler and then is fed into a medium circulation pipeline for use.

After cooling water with initial temperature enters a medium circulation pipeline, heating the cooling water to a preset reference temperature by an electric heater; if the heated cooling water is required to be cooled, the electric control valve is directly opened, the liquid inlet pipe continuously supplies the cooling water with the initial temperature into the medium circulation pipeline, and the heated cooling water is discharged from the return pipe, so that the cooling is realized. The controller combines the detection value of the reference temperature sensor (the detection value is the reference temperature value), and the heating medium is subjected to feedback adjustment in the heating or cooling mode, so that the heating medium keeps constant temperature at the reference temperature value. The controller controls the electric heater and the electric control valve based on the reference temperature value, so that the heat conducting medium maintains a constant temperature in an adjusting control mode, which is the prior art and is not described in detail herein.

As shown in fig. 3 and 5, the two ends of the sensor mounting tube 1 are respectively provided with a tube joint 11, the inner ends of the tube joints 11 are fixedly connected with the sensor mounting tube, the lower ends of the tube joints are connected with a medium circulation pipeline through a clamp 12, the upper end of one tube joint 11 extends to form an upper channel 110, the upper end of the upper channel is provided with an upper clamp seat 111, the upper end of the reference temperature sensor 4 is fixedly provided with a connecting sleeve 40, the lower end of the connecting sleeve is provided with a lower clamp seat 41, the detection end of the reference temperature sensor is axially inserted into the medium circulation pipeline from top to bottom in the upper channel, and the upper clamp seat and the lower clamp seat are connected through a clamp; the upper end of the other pipe joint is communicated with the upper end of the return pipe.

The sensor mounting pipe 1 is of a U-shaped structure, a plane formed by the sensor mounting pipe is horizontally distributed and arranged at the upper end of the medium circulation pipeline 2, a chuck interface 100 is arranged at the outer end of the connecting seat 10, and a temperature sensor to be measured is connected with the chuck interface through a clamp (a clamp is omitted in the figure, and a clamp specific structure is shown as a clamp 12); the connecting seats 10 are alternately distributed on two sides of the sensor mounting tube 1, the axes of the connecting seats penetrate through the axes of the sensor mounting tube, the outer ends of the connecting seats are obliquely distributed upwards, and an included angle of 45-60 degrees is formed between the axes of the connecting seats and the horizontal plane. The connecting seat in this embodiment is provided with ten, and two sections of U-shaped sensor installation pipe respectively set up five, and the axis of connecting seat sets up to 45 with the contained angle of horizontal plane.

As shown in fig. 6, the inner end of the connection seat 10 extends towards the inner center of the sensor mounting tube to form a closed heat conduction isolation sleeve 101, the heat conduction isolation sleeve completely isolates the heat conduction medium from the inner space of the connection seat, and the heat conduction isolation sleeve is filled with heat conduction silicone oil 102; the outer wall of the heat conducting isolation sleeve is provided with a plurality of annular grooves 103. The heat conducting medium is completely isolated from the inner wall space of the connecting seat through the heat conducting isolation sleeve, the sensor to be measured is inserted into the heat conducting silicone oil, and the heat of the heat conducting medium is transferred to the heat conducting silicone oil through the heat conducting isolation sleeve, so that the temperature of the heat conducting silicone oil is equal to that of the heat conducting medium. Because the heat conducting medium has larger pressure, when the temperature sensor to be measured is directly contacted with the heat conducting medium, the risk that the heat conducting medium permeates into the sensor to be measured exists, and the heat conducting isolation sleeve is arranged to completely isolate the heat conducting medium (water) from the temperature sensor to be measured, so that the risk is avoided, and the joint of the temperature sensor to be measured and the connecting seat is also effectively prevented from leaking; in addition, in the calibration process, as the calibration points of the temperature sensors to be measured on different biological pharmaceutical equipment are different, the temperature sensors to be measured can be detached or replaced at any time according to actual requirements in the calibration process, other temperature sensors to be measured cannot be influenced, and the use is more flexible.

A method of using a temperature sensor calibration assistance device, comprising the steps of:

s1, installing a standard temperature sensor which is detected to be qualified by a third-party detection mechanism in a medium circulation pipeline, detaching the temperature sensor to be detected from other biopharmaceutical equipment and installing the temperature sensor to be detected on a connecting seat, wherein the temperature sensor to be detected is still connected with the biopharmaceutical equipment through a data line;

s2, opening an electric control valve on the return pipe, feeding heat-conducting medium into a medium circulation pipeline from a liquid inlet pipe, closing the electric control valve after air in the medium circulation pipeline is completely discharged from the return pipe, and closing a safety valve group when the pressure in the medium circulation pipeline reaches a preset value, wherein the whole medium circulation pipeline forms a closed loop;

s3, starting a circulating pump, heating a heat-conducting medium through an electric heater, and when the detection value of a reference temperature sensor reaches a preset temperature value t1, feeding back and adjusting the heat-conducting medium in a medium circulating pipeline by a controller according to the value of t1, so that the heat-conducting medium is in a stable constant-temperature state at t1, wherein t1 is the reference temperature value;

s4, obtaining a detection value T1 of a corresponding temperature sensor to be detected from the biopharmaceutical equipment, if the detection value T1 is equal to a reference temperature value T1 or the error is within an allowable range, calibrating the temperature sensor to be detected is not needed, and if the error of the detection value T1 and the reference temperature value T1 is beyond the allowable range, calibrating the temperature sensor to be detected on the biopharmaceutical equipment directly, so that the detection value T1 is equal to the reference temperature value T1;

s5, repeating the steps S3 and S4 for a plurality of times to obtain detection values T2 and T3 … … Tn of corresponding temperature sensors to be detected under the condition of reference temperature values T2 and T3 … … Tn, comparing the detection values Tn with the reference temperature values Tn, and calibrating the corresponding temperature sensors to be detected according to the method in the step S4;

s6, after the temperature sensor to be measured is calibrated, the temperature sensor to be measured is removed from the connecting seat, cleaned and then installed in corresponding biopharmaceutical equipment.

In this embodiment, the temperature values of t1, t2, t3 … … tn are set according to the rule that t1 is set to 37 ℃, tn is set to 121 ℃, then a value is set at each interval of temperatures between 37 ℃ and 121 ℃, for example, t2 is set to 60 ℃, t3 is set to 90 ℃, 37 ℃, 60 ℃, 90 ℃ and 121 ℃ are set, and the sensor to be measured is calibrated. Those skilled in the art can increase or decrease the calibration points according to the calibration accuracy requirements of the sensor to be measured.

In the description of the present invention, it should be understood that the directions or positional relationships indicated by the upper, lower, left, right, inner, outer, one end, the other end, etc. are based on the orientations or positional relationships shown in the drawings, and are merely for the purpose of more clearly describing the technical solution of the present invention, and are not meant to indicate or imply that the device or element to be referred to must be provided with a specific direction, be configured and operated in a specific orientation, and should not be construed as limiting the present invention.

Although specific embodiments of the invention have been described in detail herein, they are presented for purposes of illustration only and are not to be construed as limiting the scope of the invention. Various substitutions, alterations, and modifications can be made without departing from the spirit and scope of the invention.

Claims (10)

1. A temperature sensor calibration auxiliary device is characterized by comprising

The sensor installation tube, two ends of the sensor installation tube are connected into a medium circulation pipeline, the medium circulation pipeline is filled with a heat-conducting medium, and the temperature of the heat-conducting medium can be changed and can be kept in different preset constant temperature states; and

the reference temperature sensor is configured to be detected to be qualified by a third-party detection mechanism, and the detection end of the reference temperature sensor stretches into the heat conducting medium to detect a reference temperature value of the heat conducting medium;

the sensor mounting tube is characterized in that a plurality of connecting seats for mounting temperature sensors to be measured are arranged on the outer side of the sensor mounting tube, the temperature sensors to be measured are detachably connected with the connecting seats, and the detection ends of the temperature sensors to be measured extend into the sensor mounting tube to detect the temperature of the heat-conducting medium and obtain detection values.

2. The auxiliary device for calibrating the temperature sensor according to claim 1, wherein an electric heater for heating the heat conducting medium and a circulating pump for driving the heat conducting medium to circulate are arranged in the medium circulating pipeline; the lower extreme of medium circulation pipeline is equipped with the feed liquor pipe, has the drain pipe on the feed liquor pipe in parallel, the junction of feed liquor pipe and drain pipe is equipped with the relief valve group that is arranged in controlling the heat conduction medium pressure in the medium circulation pipeline, be equipped with the back flow between the upper end of medium circulation pipeline and the drain pipe, be equipped with the automatically controlled valve on the back flow.

3. The auxiliary device for calibrating the temperature sensor according to claim 2, wherein the heat conducting medium adopts cooling water with an initial temperature of 5-30 ℃, the working pressure of the heat conducting medium in the medium circulation pipeline is 2.5-3.5Bar, and when the working pressure of the heat conducting medium is more than 3.5Bar, the safety valve group automatically discharges liquid and discharges pressure.

4. The auxiliary device for calibrating the temperature sensor according to claim 2, wherein the two ends of the sensor mounting pipe are respectively provided with a pipe joint, the inner ends of the pipe joints are fixedly connected with the sensor mounting pipe, and the lower ends of the pipe joints are connected with the medium circulation pipeline through hoops.

5. The auxiliary device for calibrating the temperature sensor according to claim 4, wherein the upper end of one pipe joint extends to form an upper channel, an upper clamp seat is arranged at the upper end of the upper channel, a connecting sleeve is fixedly arranged at the upper end of the reference temperature sensor, a lower clamp seat is arranged at the lower end of the connecting sleeve, the detection end of the reference temperature sensor is axially inserted into a medium circulation pipeline from top to bottom in the upper channel, and the upper clamp seat and the lower clamp seat are connected through a clamp; the upper end of the other pipe joint is communicated with the upper end of the return pipe.

6. The auxiliary device for calibrating the temperature sensor according to claim 1, wherein the sensor mounting tube is of a U-shaped structure, a plane formed by the sensor mounting tube is horizontally distributed and arranged at the upper end of the medium circulation pipeline, a chuck interface is arranged at the outer end of the connecting seat, and the temperature sensor to be tested is connected with the chuck interface through a clamp.

7. The auxiliary device for calibrating a temperature sensor according to claim 6, wherein the connecting seats are alternately arranged on both sides of the sensor mounting tube, the axes of the connecting seats penetrate through the axes of the sensor mounting tube, the outer ends of the connecting seats are obliquely upwards arranged, and an included angle of 45-60 degrees is formed between the axes of the connecting seats and the horizontal plane.

8. The auxiliary device for calibrating the temperature sensor according to claim 7, wherein the inner end of the connecting seat extends towards the inner center of the sensor mounting tube to form a sealed heat-conducting isolation sleeve, the heat-conducting isolation sleeve completely isolates a heat-conducting medium from the inner space of the connecting seat, and heat-conducting silicone oil is filled in the heat-conducting isolation sleeve; the outer wall of the heat conduction isolation sleeve is provided with a plurality of annular grooves.

9. The auxiliary device for calibrating the temperature sensor according to claim 2, further comprising a frame and a controller arranged on the frame and used for adjusting the temperature of the medium in the medium circulation pipeline, wherein the electric heater, the circulating pump and the electric control valve are all connected with the controller; the bottom of the frame is provided with a roller which is convenient to move.

10. The application method of the temperature sensor calibration auxiliary device is characterized by comprising the following steps of:

s1, installing a standard temperature sensor which is detected to be qualified by a third-party detection mechanism in a medium circulation pipeline, detaching the temperature sensor to be detected from other biopharmaceutical equipment and installing the temperature sensor to be detected on a connecting seat, wherein the temperature sensor to be detected is still connected with the biopharmaceutical equipment through a data line;

s2, opening an electric control valve on the return pipe, feeding heat-conducting medium into a medium circulation pipeline from a liquid inlet pipe, closing the electric control valve after air in the medium circulation pipeline is completely discharged from the return pipe, and closing a safety valve group when the pressure in the medium circulation pipeline reaches a preset value, wherein the whole medium circulation pipeline forms a closed loop;

s3, starting a circulating pump, heating a heat-conducting medium through an electric heater, and when the detection value of a reference temperature sensor reaches a preset temperature value t1, feeding back and adjusting the heat-conducting medium in a medium circulating pipeline by a controller according to the value of t1, so that the heat-conducting medium is in a stable constant-temperature state at t1, wherein t1 is the reference temperature value;

s4, obtaining a detection value T1 of a corresponding temperature sensor to be detected from the biopharmaceutical equipment, if the detection value T1 is equal to a reference temperature value T1 or the error is within an allowable range, calibrating the temperature sensor to be detected is not needed, and if the error of the detection value T1 and the reference temperature value T1 is beyond the allowable range, calibrating the temperature sensor to be detected on the biopharmaceutical equipment directly, so that the detection value T1 is equal to the reference temperature value T1;

s5, repeating the steps S3 and S4 for a plurality of times to obtain detection values T2 and T3 … … Tn of corresponding temperature sensors to be detected under the condition of reference temperature values T2 and T3 … … Tn, comparing the detection values Tn with the reference temperature values Tn, and calibrating the corresponding temperature sensors to be detected according to the method in the step S4;

s6, after the temperature sensor to be measured is calibrated, the temperature sensor to be measured is removed from the connecting seat, cleaned and then installed in corresponding biopharmaceutical equipment.

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