CN116036869B - Vaccine ultrafiltration system pipeline clamp - Google Patents
Vaccine ultrafiltration system pipeline clamp Download PDFInfo
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- CN116036869B CN116036869B CN202310292859.3A CN202310292859A CN116036869B CN 116036869 B CN116036869 B CN 116036869B CN 202310292859 A CN202310292859 A CN 202310292859A CN 116036869 B CN116036869 B CN 116036869B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
- B01D65/02—Membrane cleaning or sterilisation ; Membrane regeneration
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
- B01D65/10—Testing of membranes or membrane apparatus; Detecting or repairing leaks
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- Water Supply & Treatment (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
The invention relates to the technical field of pipeline connecting pieces, in particular to a pipeline clamp of a vaccine ultrafiltration system, which comprises a clamp connecting seat, a liquid inlet cavity channel, a circulating liquid outlet cavity channel, a containing bottom groove, a piston pressure plate, an interaction cavity channel, a containing sinking groove, a permeate clamping seat and a driving flashboard, wherein the liquid inlet cavity channel and the circulating liquid outlet cavity channel are penetrated and arranged in the clamp connecting seat, the containing bottom groove and the interaction cavity channel are arranged in the clamp connecting seat, and the containing bottom groove is positioned below the circulating liquid outlet cavity channel; the pipeline connecting clamp is applied to a virus tangential flow ultrafiltration system for producing vaccines, can detect the working state of a tangential flow filter, can directly send accumulated liquid in a containing bottom groove into a liquid inlet cavity channel at high pressure through a piston pressure plate through an interactive cavity channel when a filter cake layer or a gel layer is piled up on the surface of the filter membrane, increases the liquid flow rate of ultrafiltration turbulence, increases the flow shear force of the turbulence, and strips and cleans the filter cake layer or the gel layer.
Description
Technical Field
The invention relates to the technical field of pipeline connectors, in particular to a pipeline clamp of a vaccine ultrafiltration system.
Background
Tangential flow ultrafiltration systems in vaccine production are pressure driven, according to the molecular size membrane separation process, the sample mixture is not forced through a single pass through the membrane as in direct current filtration, but the fluid is passed through the surface of the membrane in a multiple recirculation fashion; a tangential flow ultrafiltration system of the prior art, such as a viral tangential flow ultrafiltration system for vaccine production as disclosed in chinese patent application CN204107336U, is described in: the utility model provides a virus tangential flow ultrafiltration system for producing vaccine, includes that the goods is irritated, permeate collection is irritated and tangential flow filter, tangential flow filter includes tangential flow upper cover, be equipped with the ultrafiltration board between tangential flow upper cover and the tangential flow upper cover, tangential flow upper cover and tangential flow lower cover compress tightly through the fastener and install together, tangential flow upper cover is equipped with feed liquor pipe, drain pipe and permeate exit tube, tangential flow upper cover is equipped with first drain hole and second drain hole, first drain hole and feed liquor pipe intercommunication, second drain hole and drain pipe intercommunication, the ultrafiltration board includes first drain ultrafiltration hole, second drain hole and ultrafiltration board filter-out part, the second drain hole corresponds with the second drain ultrafiltration hole, permeate and ultrafiltration board filter-out part intercommunication, the goods is through goods feed liquor pipe connection adjustable speed pump, adjustable speed pump connection has the feed liquor table to permeate the feed liquor pipe, the drain pipe table is connected with the drain pump, the drain pipe table is connected with the permeate table, the drain pipe is connected with the drain pipe table is connected with the drain pump table, permeate table is connected with the drain pipe.
Tangential flow ultrafiltration systems, while capable of reducing the build-up of cake or gel layers on the membrane surface, still produce some build-up during large scale ultrafiltration and become increasingly severe as the amount of ultrafiltrate increases.
Disclosure of Invention
The invention aims to provide a pipeline clamp of a vaccine ultrafiltration system, which solves the problems in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions: the utility model provides a bacterin ultrafiltration system pipeline anchor clamps, includes anchor clamps connecting seat, feed liquor chamber way, circulation flowing back chamber way, holds flourishing kerve, piston pressure disk, mutual chamber way, holding heavy groove, permeate liquid holder and drive flashboard, feed liquor chamber way and circulation flowing back chamber way have been seted up to the inside of anchor clamps connecting seat, hold flourishing kerve and mutual chamber way have been seted up to the inside of anchor clamps connecting seat, hold flourishing kerve below that lies in circulation flowing back chamber way, and with circulation flowing back chamber way intercommunication, the inside lift of holding flourishing kerve is provided with the piston pressure disk, the piston pressure disk with seal contact between the flourishing kerve, the piston pressure disk is located the top of circulation flowing back chamber way, the one end of mutual chamber way communicates with the bottom of holding kerve, the other end and feed liquor chamber way intercommunication, the holding heavy groove of holding has been seted up to the upper surface of anchor clamps connecting seat, the upper surface fixed liquid holder that is provided with of anchor clamps connecting seat, permeate liquid holder is the symmetry setting, and permeate liquid holder is the transmission and is equipped with between the pressure disk, permeate liquid holder with seal contact with the drive flashboard, seal structure has one-way to flow in one-way.
The upper surface of anchor clamps connecting seat is provided with lift actuating mechanism, lift actuating mechanism can drive piston pressure disk lift and remove, the inside of accommodation heavy groove is provided with impact generation mechanism, impact generation mechanism can dynamic change impact amplitude through drive flashboard and lift actuating mechanism cooperation.
The one-way liquid suction structure comprises a pressure plate suction hole, a suction Kong Chen groove, a one-way blocking disc and a connecting elastic sheet, wherein the pressure plate suction hole penetrates through the surface of the piston pressure plate, the suction Kong Chen groove is formed in the lower surface of the piston pressure plate and coaxially corresponds to the pressure plate suction hole, the one-way blocking disc is arranged in the suction Kong Chen groove, the one-way blocking disc is blocked at the lower part of the pressure plate suction hole, and the connecting elastic sheet is connected between the one-way blocking disc and the inner wall surface of the suction Kong Chen groove.
The unidirectional flow structure comprises a ball cavity, a blocking ball and a pressing and holding spring, wherein the ball cavity is arranged in the clamp connecting seat, the ball cavity is communicated with the interaction cavity, the blocking ball is arranged in the ball cavity, and the pressing and holding spring is arranged on the upper portion of the blocking ball.
The lifting driving mechanism comprises a sealing socket, a lifting plugboard, a threaded through hole, a motor frame, a driving motor, a screw rod and a transverse connecting plate, wherein the sealing socket is fixedly arranged at the upper surface of the clamp connecting seat, the lifting plugboard is arranged in the sealing socket in a penetrating and inserting mode, the lower end of the lifting plugboard is fixedly arranged on the upper surface of the piston pressure plate, and the threaded through hole is formed in the upper portion of the lifting plugboard in a penetrating mode.
The upper surface position of anchor clamps connecting seat is fixed and is provided with the motor frame, the fixed surface of motor frame is provided with driving motor, driving motor with the lead screw transmission is installed, the lead screw alternates through the screw through-hole, and spiral cooperation with it, the fixed surface of lift picture peg is provided with the cross connection board, the cross connection board with drive flashboard fixed mounting.
The impact generating mechanism comprises an interaction hole, a positioning sleeve, a corrugated bag, an extrusion end disc, a reset supporting spring, an electric control impact box, an impact shaft, a positioning platen, a platen shaft, a limiting shaft disc, a platen supporting spring, a track anti-tilting plate and a track groove, wherein the interaction hole is formed in the position of the lower surface of the inside of the accommodating sink groove, the lower part of the interaction hole is communicated with the interaction cavity, the positioning sleeve is fixedly arranged on the lower surface of the inside of the accommodating sink groove, the positioning sleeve is covered outside the interaction hole, the corrugated bag is arranged in the positioning sleeve, the extrusion end disc is fixedly arranged on the upper end cover of the corrugated bag, and the reset supporting spring is arranged between the extrusion end disc and the lower surface of the inside of the accommodating sink groove.
The automatic impact device is characterized in that an electric control impact box is arranged above the extrusion end disc, an impact shaft is arranged at the lower part of the electric control impact box, a positioning platen is fixedly arranged on the upper surface of the electric control impact box, a platen shaft is vertically inserted in the positioning platen, a limiting shaft disc is fixedly arranged at the upper end of the platen shaft, a platen supporting spring is sleeved outside the platen shaft and arranged between the lower surface of the positioning platen and the lower surface of the inner part of the accommodating sink, a rail anti-tilting plate is fixedly arranged on the upper surface of the positioning platen, a rail groove is formed in the surface of the rail anti-tilting plate, and one side of the driving flashboard is slidably embedded in the rail groove.
The outside intercommunication of anchor clamps connecting seat is provided with feed liquor pipe, feed liquor exit tube, circulation exit tube and circulation feed liquor exit tube, the feed liquor pipe passes through feed liquor chamber way and feed liquor exit tube intercommunication, circulation feed liquor pipe passes through circulation flowing back chamber way and circulation exit tube intercommunication, pressure sensor is installed to the surface spiral of anchor clamps connecting seat, pressure sensor surveys the inside of going into the feed liquor chamber way.
The inside of permeating liquid holder is run through and is offered the holder through-hole, the fixed surface of permeating liquid holder is provided with the permeate liquid pipe, permeate liquid pipe with the holder through-hole intercommunication, the surface of drive flashboard is run through and is offered normally open and correspond the hole, two sets of the holder through-hole is through normally open and corresponds the coaxial correspondence intercommunication of hole.
Compared with the prior art, the invention has the beneficial effects that:
the pipeline connecting clamp is applied to a virus tangential flow ultrafiltration system for producing vaccines, can detect the working state of a tangential flow filter, can directly send accumulated liquid in a containing bottom groove into a liquid inlet cavity channel at high pressure through a piston pressure plate through an interaction cavity channel when a filter cake layer or a gel layer is piled up on the surface of the filter membrane, increases the liquid flow rate of ultrafiltration turbulence, increases the flow shear force of the turbulence, peels off and cleans the filter cake layer or the gel layer, and keeps the high-efficiency ultrafiltration of the filter membrane.
Through the impact generating mechanism, the liquid fed into the liquid inlet cavity channel through the interaction cavity channel can generate flow impact, so that the flow shearing force of turbulent flow is fluctuated, and the stripping and cleaning capacity is improved; meanwhile, the impact generating mechanism can dynamically change the impact amplitude by matching the driving flashboard with the lifting driving mechanism, the impact generating mechanism outputs impact with low amplitude at the front section of the downward movement of the piston pressure plate, so that the flow shearing force is caused to impact with low amplitude, firstly, a filter cake layer or a gel layer is loosened, and the impact generating mechanism linearly improves the amplitude under the extrusion of the driving flashboard at the tail section of the downward movement of the piston pressure plate, so that the fluctuation amplitude of the flow shearing force is gradually increased, and the loosened filter cake layer or gel layer is efficiently stripped.
Through the cooperation of the permeate liquid holder that sets up and drive flashboard, can carry out the cooperation control to the permeate liquid after the ultrafiltration, when increasing turbulent flow shear force, can close permeate liquid discharge end for the permeate liquid filtration outflow side of filter membrane is in the malleation closed state, reduces the piece that filter cake layer or gel layer produced by impact pressure and extrudees in the filter membrane thru hole.
Drawings
FIG. 1 is a schematic diagram of the overall structure of the present invention.
Fig. 2 is a top view of the overall structure of the present invention.
Fig. 3 is a front view of the overall structure of the present invention.
Fig. 4 is a perspective semi-cutaway view of the overall structure of the present invention.
Fig. 5 is an enlarged schematic view of the area a in fig. 4.
Fig. 6 is an enlarged schematic view of region B in fig. 4.
Fig. 7 is a front perspective semi-cutaway view of the overall structure of the present invention.
FIG. 8 is a schematic view of the overall structure of the present invention in a perspective, semi-cut-away, and at another angle.
Fig. 9 is a perspective semi-cutaway view of the circulation outlet tube of the present invention.
Fig. 10 is a perspective semi-cutaway side view of the circulation tube of the present invention.
In the figure: 1. a clamp connecting seat; 2. a liquid inlet channel; 3. a circulation drain channel; 4. a holding bottom groove; 5. a piston pressure plate; 6. an interaction channel; 7. the accommodating sink groove; 8. a permeate holder; 9. driving the flashboard; 501. a pressure plate suction hole; 502. suction Kong Chencao; 503. a one-way plugging disc; 504. a connecting spring plate; 601. a ball cavity; 602. blocking balls; 603. pressing the holding spring; 101. sealing the socket; 102. lifting plugboards; 103. a threaded through hole; 104. a motor frame; 105. a driving motor; 106. a screw rod; 107. a transverse connecting plate; 701. an interaction hole; 702. positioning the sleeve; 703. a bellows; 704. extruding an end disc; 705. resetting the supporting spring; 706. an electric control impact box; 707. an impact shaft; 708. positioning a bedplate; 709. a platen shaft; 710. limiting shaft disc; 711. platen support springs; 712. a track anti-tilting plate; 713. a track groove; 108. a liquid inlet pipe; 109. a liquid inlet pipe and a liquid outlet pipe; 110. a circulation outlet pipe; 111. circulating the pipe; 112. a pressure sensor; 801. a permeate tube; 802. a holder through hole; 901. a normally open corresponding hole; 113. a pipe clamp cap; 114. the pipeline clamps the inclined ring.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1 to 10, the present invention provides a technical solution: the utility model provides a bacterin ultrafiltration system pipeline anchor clamps, including anchor clamps connecting seat 1, the feed liquor chamber way 2, circulation flowing back chamber way 3, hold flourishing kerve 4, piston pressure disk 5, mutual chamber way 6, the heavy groove of holding 7, see through liquid holder 8 and drive flashboard 9, feed liquor chamber way 2 and circulation flowing back chamber way 3 have been seted up to the inside of anchor clamps connecting seat 1, hold flourishing kerve 4 and mutual chamber way 6 have been seted up to the inside of anchor clamps connecting seat 1, hold flourishing kerve 4 is located circulation flowing back chamber way 3 below, and with circulation flowing back chamber way 3 intercommunication, the inside lift of holding kerve 4 is provided with piston pressure disk 5, sealing contact between piston pressure disk 5 and the flourishing kerve 4, piston pressure disk 5 is located circulation flowing back chamber way 3's top, the one end of mutual chamber way 6 and the bottom intercommunication of holding kerve 4, the other end and feed liquor chamber way 2 intercommunication of mutual chamber way 6, the upper surface of anchor clamps connecting seat 1 has been seted up the heavy groove of holding 7, the upper surface fixation of anchor clamps connecting seat 1 is provided with see through liquid holder 8, see through liquid holder 8 is the setting up and see through liquid holder 8 and is the setting up between the symmetry, and see through liquid holder 8 has the drive flashboard 9, the one-way structure is opened with the inside sealing contact of drive, the one-way 5 is sealed with the inside of holding the liquid clamp 6.
The upper surface of anchor clamps connecting seat 1 is provided with lift actuating mechanism, and lift actuating mechanism can drive piston pressure disk 5 lift and remove, and the inside of accommodation heavy groove 7 is provided with impact generation mechanism, and impact generation mechanism passes through drive flashboard 9 and lift actuating mechanism cooperation and can dynamic change impact amplitude.
The unidirectional liquid suction structure comprises a pressure plate suction hole 501, suction Kong Chencao, a unidirectional blocking plate 503 and a connecting elastic sheet 504, wherein the pressure plate suction hole 501 penetrates through the surface of the piston pressure plate 5, suction Kong Chencao is arranged at the lower surface of the piston pressure plate 5 and coaxially corresponds to the pressure plate suction hole 501, the unidirectional blocking plate 503 is arranged in the suction Kong Chen groove 502, the unidirectional blocking plate 503 is blocked at the lower part of the pressure plate suction hole 501, the connecting elastic sheet 504 is arranged between the unidirectional blocking plate 503 and the inner wall surface of the suction Kong Chen groove 502, and when the piston pressure plate 5 moves upwards, the unidirectional liquid suction structure can prevent the piston pressure plate 5 from being sucked by negative pressure and can reversely suck liquid stored on the upper surface of the piston pressure plate 5, so that the circulation liquid discharge of the circulation pipe 110 is more stable.
The unidirectional flow structure comprises a ball cavity 601, a blocking ball 602 and a pressing spring 603, wherein the ball cavity 601 is arranged in the clamp connecting seat 1, the ball cavity 601 is communicated with the interaction cavity 6, the blocking ball 602 is arranged in the ball cavity 601, and the pressing spring 603 is arranged on the upper portion of the blocking ball 602.
The lifting driving mechanism comprises a sealing socket 101, a lifting plugboard 102, a threaded through hole 103, a motor frame 104, a driving motor 105, a screw rod 106 and a transverse connecting plate 107, wherein the sealing socket 101 is fixedly arranged at the upper surface of the fixture connecting seat 1, the lifting plugboard 102 is arranged in the sealing socket 101 in a sealing and penetrating mode, the lower end of the lifting plugboard 102 is fixedly arranged on the upper surface of the piston pressure plate 5, and the threaded through hole 103 is formed in the upper portion of the lifting plugboard 102 in a penetrating mode.
The upper surface position of anchor clamps connecting seat 1 is fixed and is provided with motor frame 104, and the fixed surface of motor frame 104 is provided with driving motor 105, and driving motor 105 and lead screw 106 transmission installation, lead screw 106 alternate through screw through-hole 103, and spiral cooperation with it, and the fixed surface of lift picture peg 102 is provided with horizontal link plate 107, horizontal link plate 107 and drive flashboard 9 fixed mounting.
The impact generating mechanism comprises an interaction hole 701, a positioning sleeve 702, a corrugated bag 703, an extrusion end disc 704, a reset supporting spring 705, an electric control impact box 706, an impact shaft 707, a positioning platen 708, a platen shaft 709, a limiting shaft disc 710, a platen supporting spring 711, a track anti-tilting plate 712 and a track groove 713, wherein the interaction hole 701 is formed in the position of the lower surface of the inner part of the accommodating sink 7, the lower part of the interaction hole 701 is communicated with the interaction cavity 6, the positioning sleeve 702 is fixedly arranged on the lower surface of the inner part of the accommodating sink 7, the positioning sleeve 702 is covered outside the interaction hole 701, the corrugated bag 703 is arranged in the positioning sleeve 702, the extrusion end disc 704 is fixedly arranged on the upper end cover of the corrugated bag 703, and the reset supporting spring 705 is arranged between the extrusion end disc 704 and the lower surface of the inner part of the accommodating sink 7.
An electric control impact box 706 is arranged above the extrusion end disc 704, an impact shaft 707 is arranged at the lower part of the electric control impact box 706, a positioning platen 708 is fixedly arranged on the upper surface of the electric control impact box 706, a platen shaft 709 is vertically inserted in the positioning platen 708, a limiting shaft disc 710 is fixedly arranged at the upper end of the platen shaft 709, a platen supporting spring 711 is sleeved outside the platen shaft 709, the platen supporting spring 711 is arranged between the lower surface of the positioning platen 708 and the inner lower surface of the accommodating sink 7, a track anti-tilting plate 712 is fixedly arranged on the upper surface of the positioning platen 708, a track groove 713 is formed in the surface of the track anti-tilting plate 712, and one side of the driving flashboard 9 is slidably embedded in the track groove 713.
The outside intercommunication of anchor clamps connecting seat 1 is provided with feed liquor pipe 108, feed liquor exit tube 109, circulation exit tube 110 and circulation feed liquor exit tube 111, feed liquor pipe 108 communicates with feed liquor exit tube 109 through feed liquor chamber way 2, circulation feed liquor exit tube 111 communicates with circulation exit tube 110 through circulation flowing back chamber way 3, pressure sensor 112 is installed to the surface spiral of anchor clamps connecting seat 1, pressure sensor 112 stretches into the inside of feed liquor chamber way 2, the surface of feed liquor pipe 108, feed liquor exit tube 109, circulation exit tube 110 and circulation feed liquor exit tube 111 is all fixed respectively and is provided with pipeline clamping diagonal ring 114, install pipeline clamping cap 113 to pipeline clamping diagonal ring 114's outside cover, the pipeline extrusion clamp of ultrafiltration system is established between pipeline clamping diagonal ring 114 and pipeline clamping cap 113, thereby realize that the intercommunication is fixed.
The inside of permeating liquid holder 8 runs through and has offered holder through-hole 802, and the fixed surface of permeating liquid holder 8 is provided with permeating liquid pipe 801, permeates liquid pipe 801 and holder through-hole 802 intercommunication, and the surface of drive flashboard 9 runs through and has offered normally open corresponding hole 901, and two sets of holder through-holes 802 correspond the intercommunication through normally open corresponding hole 901 is coaxial.
When the invention is used, the pump outlet pipe of the sample mixed solution is communicated with the liquid inlet pipe 108, and then is output through the liquid inlet pipe 109 and is communicated with the liquid inlet pipe of the tangential flow filter; the liquid outlet pipe of the tangential flow filter is communicated with the circulating inlet pipe 111, then is output and sent to a liquid outlet valve through the circulating outlet pipe 110, and finally is circulated into a product tank of the sample mixed liquid; the permeate outlet pipe of the tangential flow filter communicates with the permeate pipe 801 on one side and then passes through the permeate pipe 801 on the other side to be output.
Under the conventional state, liquid in the sample mixed liquid product tank is driven by a liquid pump, firstly passes through the liquid inlet channel 2 and then is sent into the tangential flow filter for ultrafiltration, after ultrafiltration circulating liquid passes through the circulating liquid outlet channel 3, the liquid is discharged back to the sample mixed liquid product tank, and ultrafiltration permeate passes through the clamping seat through hole 802 and the normally open corresponding hole 901 and is output.
The pressure sensor 112 detects the inside hydraulic pressure of feed liquor chamber 2 in real time, when the filter cake layer or the gel layer on milipore filter surface piles up gradually, because the input flow of liquid pump is stable, can make the inside hydraulic pressure of feed liquor chamber 2 rise gradually, when surpassing certain interval, it is serious to state that the filter cake layer or the gel layer on milipore filter surface pile up, driving motor 105 moves this moment, driving piston pressure disk 5 moves down, along with the downwardly moving of piston pressure disk 5, can hold the liquid that holds in the bottom tank 4 through interactive chamber 6, squeeze into in the feed liquor chamber 2, increase the inside liquid flow of feed liquor chamber 2, the liquid is in a large amount of squeeze into in the feed liquor chamber 2 in the short time, can make the flow that feed liquor exit tube 109 exports tangential flow filter increases, because the sectional area of tangential flow filter inside runner is unchangeable, consequently, can make the turbulent flow shear force on filter membrane surface increase, carry out the peel off impact clearance to filter cake layer or gel layer, this kind of mode is compared with the mode that utilizes the increase power to increase the flow, the input quantity that the liquid pump improves in the short moment increases, and the input extrusion force is greater than the liquid pump, and the risk of burning out the pump has been avoided greatly in a short time, thereby the risk of cleaning up the liquid pump has been avoided.
While the driving motor 105 is running, the electric control impact box 706 runs synchronously, the impact shaft 707 is controlled to reciprocate with a fixed stroke, as shown in fig. 4, in the front section of the downward movement of the piston platen 5, the positioning platen 708 is under the support of the platen supporting spring 711 and is at the highest position, at this time, the impact shaft 707 can only impact the extrusion end disc 704 slightly within the range of the stroke, so that the extrusion end disc 704 moves slightly downward, in the rear section of the downward movement of the piston platen 5, under the extrusion of the driving gate 9, the positioning platen 708 gradually goes down, so that the impact amplitude of the impact shaft 707 on the extrusion end disc 704 is gradually increased within the range of the stroke, and thus the impact amplitude is dynamically changed, when the extrusion end disc 704 is driven by the downward impact of the control impact shaft 707, the bellows 703 is compressed, so that the liquid in the bellows 703 is extruded into the interaction cavity 6 through the interaction hole 701, the flow rate of the liquid in the bellows 703 is increased in a short time, and when the impact shaft is controlled to move upward under the support of the reset supporting spring 704, so that the flow rate of the bellows 703 is reduced in the interaction cavity 6, and the flow rate of the liquid in the interaction cavity 6 is sucked up through the interaction cavity 707 in a short time, so that the flow rate of the bellows 703 is blown down in the interaction cavity 6.
As shown in fig. 1, the permeate tube 801 is symmetrically arranged front and back, the holder through holes 802 are formed in the permeate holder 8, the permeate tube 801 is correspondingly communicated with the holder through holes 802 coaxially, the driving flashboard 9 is inserted between the two groups of holder through holes 802, and normally open corresponding holes 901 of the driving flashboard 9 are correspondingly communicated with the holder through holes 802 on two sides coaxially in an initial state, so that liquid discharged from the permeate tube of the tangential flow filter is input through the permeate tube 801 on one side, sequentially passes through the holder through holes 802, the corresponding holes 901 and the holder through holes 802 and then is discharged from the permeate tube 801 on the other side, when the piston platen 5 is driven to move downwards, the driving flashboard 9 moves downwards, so that the holder through holes 802 on two sides are staggered with the normally open corresponding holes 901, the permeate discharge end of the filter membrane is closed, the permeate liquid discharge side of the filter membrane is in a positive pressure closed state, and the filter cake layer or fragments generated by the gel layer are reduced to be extruded into the through holes by impact pressure.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. The utility model provides a bacterin ultrafiltration system pipeline anchor clamps, includes anchor clamps connecting seat (1), feed liquor chamber way (2), circulation flowing back chamber way (3), holds basal groove (4), piston pressure disk (5), mutual chamber way (6), holding sink (7), permeate liquid holder (8) and drive flashboard (9), its characterized in that: the inside of anchor clamps connecting seat (1) runs through and has seted up feed liquor chamber way (2) and circulation flowing back chamber way (3), hold holding tank (4) and mutual chamber way (6) have been seted up to the inside of anchor clamps connecting seat (1), hold holding tank (4) are located the below of circulation flowing back chamber way (3), and with circulation flowing back chamber way (3) intercommunication, hold holding tank (4)'s inside lift is provided with piston pressure disk (5), piston pressure disk (5) with hold sealing contact between holding tank way (4), piston pressure disk (5) are located the top of circulation flowing back chamber way (3), the one end and the bottom intercommunication of holding tank way (4) of mutual chamber way (6), the other end and feed liquor chamber way (2) intercommunication of mutual chamber way (6), hold tank (7) have been seted up to the upper surface of anchor clamps connecting seat (1), the upper surface fixation of anchor clamps connecting seat (1) is provided with and sees through liquid pressure disk (8), see through liquid pressure disk (8) and is symmetrical, and is equipped with the drive flashboard (8) and is equipped with one-way structure that the top that the seal is crossed and is equipped with between the seal clip seat (8) and the seal structure (9), the upper surface of the fixture connecting seat (1) is provided with a lifting driving mechanism, the lifting driving mechanism can drive the piston pressure plate (5) to move in a lifting manner, an impact generating mechanism is arranged in the accommodating sink (7), the impact generating mechanism can dynamically change the impact amplitude through the cooperation of the driving flashboard (9) and the lifting driving mechanism, the impact generating mechanism comprises an interaction hole (701), a positioning sleeve (702), a bellows (703), a pressing end plate (704), a reset supporting spring (705), an electric control impact box (706), an impact shaft (707), a positioning platen (708), a platen shaft (709), a limiting shaft plate (710), a platen supporting spring (711), a track anti-tilting plate (712) and a track groove (713), the interaction hole (701) is arranged at the position of the inner lower surface of the accommodating sink (7), the lower part of the interaction hole (701) is communicated with the interaction cavity (6), the inner lower surface of the accommodating sink (7) is fixedly provided with a positioning sleeve (702), the positioning sleeve (702) is covered outside the interaction hole (701), the positioning sleeve (704) is provided with the bellows (703), the inner end cap (703) is fixedly provided with the bellows (703), a reset supporting spring (705) is arranged between the extrusion end disc (704) and the inner lower surface of the accommodating sink (7), an electric control impact box (706) is arranged above the extrusion end disc (704), an impact shaft (707) is arranged at the lower part of the electric control impact box (706), a positioning platen (708) is fixedly arranged on the upper surface of the electric control impact box (706), a platen shaft (709) is vertically inserted in the positioning platen (708), a limiting shaft disc (710) is fixedly arranged at the upper end of the platen shaft (709), a platen supporting spring (711) is sleeved outside the platen shaft (709), the platen supporting spring (711) is arranged between the lower surface of the positioning platen (708) and the inner lower surface of the accommodating sink (7), a track anti-tilting plate (712) is fixedly arranged on the upper surface of the track anti-tilting plate (712), one side of the driving platen (9) is slidingly embedded in the inside the track groove (713), the clamp (1) is connected with the circulating inlet pipe (108) and the circulating inlet pipe (108) are communicated with the circulating inlet pipe (108) and the outlet pipe (108) through the circulating inlet pipe (108), the circulating inlet pipe (111) is communicated with the circulating outlet pipe (110) through the circulating drain cavity (3), a pressure sensor (112) is spirally arranged on the surface of the clamp connecting seat (1), the pressure sensor (112) is inserted into the liquid inlet cavity (2), a clamping seat through hole (802) is formed in the penetrating liquid clamping seat (8) in a penetrating mode, a penetrating liquid pipe (801) is fixedly arranged on the surface of the penetrating liquid clamping seat (8), the penetrating liquid pipe (801) is communicated with the clamping seat through hole (802), normally open corresponding holes (901) are formed in the surface of the driving flashboard (9) in a penetrating mode, the two groups of clamping seat through holes (802) are correspondingly communicated coaxially through the normally open corresponding holes (901), a sample mixed liquid pumping outlet pipe is communicated with the liquid inlet pipe (108), and then output through the liquid inlet pipe (109) and communicated with a liquid inlet pipe of the tangential flow filter; the liquid outlet pipe of the tangential flow filter is communicated with a circulating inlet pipe (111), then is output and sent to a liquid outlet valve through a circulating outlet pipe (110), and finally is circulated into a product tank of the sample mixed liquid; the permeate outlet pipe of the tangential flow filter is communicated with the permeate pipe (801) on one side and then is output through the permeate pipe (801) on the other side.
2. A vaccine ultrafiltration system tubing clip as claimed in claim 1, wherein: the unidirectional liquid suction structure comprises a pressure plate suction hole (501), a suction Kong Chen groove (502), a unidirectional blocking disc (503) and a connecting elastic sheet (504), wherein the pressure plate suction hole (501) penetrates through the surface of a piston pressure plate (5), the suction Kong Chen groove (502) is formed in the lower surface of the piston pressure plate (5) and coaxially corresponds to the pressure plate suction hole (501), the unidirectional blocking disc (503) is arranged in the suction Kong Chen groove (502), the unidirectional blocking disc (503) is blocked at the lower part of the pressure plate suction hole (501), and the connecting elastic sheet (504) is connected between the unidirectional blocking disc (503) and the inner wall surface of the suction Kong Chen groove (502).
3. A vaccine ultrafiltration system tubing clip as claimed in claim 1, wherein: the unidirectional flow structure comprises a ball cavity (601), a blocking ball (602) and a pressing spring (603), wherein the ball cavity (601) is arranged in the clamp connecting seat (1), the ball cavity (601) is communicated with the interaction cavity (6), the blocking ball (602) is arranged in the ball cavity (601), and the pressing spring (603) is arranged on the upper portion of the blocking ball (602).
4. A vaccine ultrafiltration system tubing clip as claimed in claim 1, wherein: the lifting driving mechanism comprises a sealing socket (101), a lifting inserting plate (102), a threaded through hole (103), a motor frame (104), a driving motor (105), a screw rod (106) and a transverse connecting plate (107), wherein the sealing socket (101) is fixedly arranged at the upper surface of the clamp connecting seat (1), the lifting inserting plate (102) is arranged in the sealing socket (101) in a sealing penetrating mode, the lower end of the lifting inserting plate (102) is fixedly mounted with the upper surface of the piston pressure plate (5), and the threaded through hole (103) is formed in the upper portion of the lifting inserting plate (102) in a penetrating mode.
5. A vaccine ultrafiltration system tubing clip as defined in claim 4, wherein: the fixture is characterized in that a motor frame (104) is fixedly arranged on the upper surface of the fixture connecting seat (1), a driving motor (105) is fixedly arranged on the surface of the motor frame (104), the driving motor (105) is in transmission installation with a screw rod (106), the screw rod (106) penetrates through a threaded through hole (103) and is in spiral fit with the threaded through hole, a transverse connection plate (107) is fixedly arranged on the outer surface of the lifting inserting plate (102), and the transverse connection plate (107) is fixedly installed with the driving flashboard (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310292859.3A CN116036869B (en) | 2023-03-24 | 2023-03-24 | Vaccine ultrafiltration system pipeline clamp |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310292859.3A CN116036869B (en) | 2023-03-24 | 2023-03-24 | Vaccine ultrafiltration system pipeline clamp |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN116036869A CN116036869A (en) | 2023-05-02 |
| CN116036869B true CN116036869B (en) | 2023-08-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310292859.3A Active CN116036869B (en) | 2023-03-24 | 2023-03-24 | Vaccine ultrafiltration system pipeline clamp |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879949A (en) * | 2005-06-18 | 2006-12-20 | 邓梁 | Frequency-modulating amplitude-modulating turbulence type film filtering system |
| JP2010247074A (en) * | 2009-04-16 | 2010-11-04 | Toppan Printing Co Ltd | Washing method of ultrafiltration filter and developing device using the ultrafiltration filter |
| CN102895879A (en) * | 2012-09-03 | 2013-01-30 | Acs农化系统有限公司 | Method and apparatus for improving membrane filtration process |
| CN103608297A (en) * | 2011-04-27 | 2014-02-26 | 生命吸管有限公司 | Water purification device |
| CN114618305A (en) * | 2022-03-31 | 2022-06-14 | 福州大学 | Method for reducing membrane pollution and improving membrane flux by using oscillatory flow process |
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2023
- 2023-03-24 CN CN202310292859.3A patent/CN116036869B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879949A (en) * | 2005-06-18 | 2006-12-20 | 邓梁 | Frequency-modulating amplitude-modulating turbulence type film filtering system |
| JP2010247074A (en) * | 2009-04-16 | 2010-11-04 | Toppan Printing Co Ltd | Washing method of ultrafiltration filter and developing device using the ultrafiltration filter |
| CN103608297A (en) * | 2011-04-27 | 2014-02-26 | 生命吸管有限公司 | Water purification device |
| CN102895879A (en) * | 2012-09-03 | 2013-01-30 | Acs农化系统有限公司 | Method and apparatus for improving membrane filtration process |
| CN114618305A (en) * | 2022-03-31 | 2022-06-14 | 福州大学 | Method for reducing membrane pollution and improving membrane flux by using oscillatory flow process |
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|---|---|
| CN116036869A (en) | 2023-05-02 |
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