CN116012313A - Biological detection rechecking request system based on density analysis - Google Patents

Biological detection rechecking request system based on density analysis Download PDF

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Publication number
CN116012313A
CN116012313A CN202211643010.8A CN202211643010A CN116012313A CN 116012313 A CN116012313 A CN 116012313A CN 202211643010 A CN202211643010 A CN 202211643010A CN 116012313 A CN116012313 A CN 116012313A
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container
virus
density
detected
processing unit
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请求不公布姓名
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Taizhou Alston Biotechnology Co ltd
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Taizhou Alston Biotechnology Co ltd
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Priority to GBGB2307889.2A priority patent/GB202307889D0/en
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Abstract

The invention relates to a biological detection rechecking request system based on density analysis, which comprises: the alternating current driving motor is used for completing stepping driving of a transmission belt of the customized transmission mechanism once every set time length so as to switch each container to be detected from the current position of the container to be detected to the position of the container to be detected before the container to be detected; a density judgment device for determining a virus distribution density; and the rechecking request device is used for sending out a rechecking request signal when the virus distribution density is between zero and a set density threshold value. The biological detection rechecking request system based on density analysis has compact logic and simple and convenient operation. By introducing a targeted picture enhancement mechanism and a picture analysis mechanism of microscopic pictures in a container to be detected, the virus distribution quantity and the virus distribution density are effectively measured, and whether the virus recheck is needed or not is determined according to the numerical distribution position of the concurrent distribution density, so that the stability and the reliability of detection data are improved.

Description

Biological detection rechecking request system based on density analysis
Technical Field
The invention relates to the field of biological detection, in particular to a biological detection rechecking request system based on density analysis.
Background
Virus detection is an important classification of biological detection, different viruses have different appearance characteristics, for example, novel coronaviruses are round or oval, have diameters of 60-140nm, have envelopes outside the virus, and contain 5 essential genes including matrix proteins, spinous process proteins, nucleoproteins, viral envelopes, and RNA-dependent RNA polymerase.
The virus detection method comprises the following steps: the characteristic detection method, the nucleic acid detection method, the behavior monitoring method and the software simulation method are different in principle, different in cost and detection range in implementation, and have various advantages. The feature detection method is one of the most commonly used virus detection methods. For example, the identification of each novel coronavirus may be performed by a reference profile of a circular or elliptical shape of the novel coronavirus body and a plurality of spike proteins attached to the body, thereby judging the distribution density of the novel coronavirus based on the number of novel coronaviruses per unit area.
However, in the actual virus detection process, due to the transmission leakage problem, the detection pollution problem and the mixed tube detection problem, trace viruses are easily detected, but in fact, the detected personnel do not have the virus infection, and at this time, the virus recheck is needed to carry out further confirmation, so that the misoperation of subsequent diagnosis is avoided. However, the limitation of virus detection itself, and the high accuracy required for detecting a minute amount of virus, results in that the determination of whether or not to re-detect is not possible in one detection, and thus the detection of infectious virus must be re-detected or confirmed once the virus is detected.
The prior art has little to study, and has disclosed: for example, the invention publication with the application publication number of CN113284023A provides a public health prevention and control comprehensive monitoring and control platform, which comprises a field rapid diagnosis detection module, a data monitoring and analysis module and a space environment management and control module. The on-site rapid diagnosis detection module is used for dynamically and continuously capturing and purifying biological particulate matters and aerosol spray in the air, detecting and monitoring virus distribution and group screening in a closed, semi-closed or relatively closed public environment. The data monitoring analysis module includes a first on-site treatment module and a first long-term treatment module. The spatial environment management and control module comprises a second field treatment module and a second long-acting treatment module. Or the invention publication with the application publication number of CN114608177A discloses a control method of an ultraviolet automatic sterilization and disinfection fresh air system, which comprises the following steps: monitoring environmental parameters in a space in real time, and collecting environmental parameter information in the space; when the collected environmental parameter information accords with the ultraviolet light starting condition, controlling the ultraviolet lamp to be started; the environmental parameter information comprises animal distribution information and virus distribution information and/or bacteria distribution information in space; and when no animal distribution exists in the space and the bacterial and/or viral distribution exceeds the standard, controlling the ultraviolet lamp to be started.
Disclosure of Invention
Compared with the prior art, the invention provides a biological detection re-inspection request system based on density analysis, which can introduce a targeted picture enhancement mechanism and a picture analysis mechanism of microscopic pictures in a container to be detected, realize accurate measurement of virus distribution quantity and virus distribution density, and determine whether virus re-inspection is needed according to the numerical distribution position of specific concurrent distribution density, thereby avoiding excessive re-inspection and reducing the occurrence probability of virus detection errors.
According to an aspect of the present invention, there is provided a biological detection review request system based on density analysis, the system including:
the alternating current driving motor is used for completing stepping driving action of a transmission belt of the customized transmission mechanism once every set time length so as to switch each container to be detected from the current position of the container to be detected to the position of the container to be detected before the container to be detected;
the customized transmission mechanism comprises a transmission support frame body, a driving wheel, a follower wheel and a transmission belt, and further comprises a groove body container which is fixed on the transmission belt and is uniformly embedded into a plurality of containers to be detected along the advancing direction of the transmission belt;
the microscopic imaging device is connected with the alternating current driving motor and is used for penetrating into a container to be detected at the current detection position under the microscopic imaging device after the alternating current driving motor finishes the step driving action of the transmission belt of the customized transmission mechanism every time, and performing microscopic picture acquisition on the container to be detected at the current detection position so as to obtain a container internal picture;
a grading processing device connected with the microscopic imaging device and used for sequentially executing contrast improvement processing, statistical ordering filtering processing and filter-based sharpening processing on the received images in the container so as to obtain grading processing images;
the shape matching device is connected with the grading processing device and is used for acquiring each image block corresponding to each virus object in the received grading processing picture based on the virus appearance characteristics, and removing the image blocks with the area smaller than the set area limit in each image block to acquire a plurality of residual image blocks;
the density judging device is connected with the shape matching device and is used for determining corresponding virus distribution density based on the number of the remaining image blocks, and the determined corresponding virus distribution density is positively associated with the number of the remaining image blocks;
the rechecking request device is connected with the density judging device and is used for sending a rechecking request signal when the received virus distribution density is between zero and a set density threshold value and sending a virus clearing signal when the received virus distribution density is zero;
the rechecking request device is also used for sending out a virus detection signal when the received virus distribution density is greater than the set density threshold value.
The biological detection rechecking request system based on density analysis has compact logic and simple and convenient operation. By introducing a targeted picture enhancement mechanism and a picture analysis mechanism of microscopic pictures in a container to be detected, the virus distribution quantity and the virus distribution density are effectively measured, and whether the virus recheck is needed or not is determined according to the numerical distribution position of the concurrent distribution density, so that the stability and the reliability of detection data are improved.
Drawings
Embodiments of the present invention will be described below with reference to the accompanying drawings, in which:
fig. 1 is an internal structural view of a biological detection review request system based on density analysis according to a first embodiment of the present invention.
Fig. 2 is an internal structural view of a biological detection review request system based on density analysis according to a second embodiment of the present invention.
Fig. 3 is an internal structural view of a biological detection review request system based on density analysis according to a third embodiment of the present invention.
Detailed Description
Embodiments of the density analysis-based bio-detection review request system of the present invention will be described in detail with reference to the accompanying drawings.
First embodiment
Fig. 1 is an internal structural view of a biological detection review request system based on density analysis according to a first embodiment of the present invention, the system including:
the alternating current driving motor is used for completing stepping driving action of a transmission belt of the customized transmission mechanism once every set time length so as to switch each container to be detected from the current position of the container to be detected to the position of the container to be detected before the container to be detected;
for example, completing the step driving action of the conveying belt of the customized conveying mechanism once every set time length includes: every 5 seconds, finishing the stepping driving action of the transmission belt of the customized transmission mechanism;
the customized transmission mechanism comprises a transmission support frame body, a driving wheel, a follower wheel and a transmission belt, and further comprises a groove body container which is fixed on the transmission belt and is uniformly embedded into a plurality of containers to be detected along the advancing direction of the transmission belt;
the microscopic imaging device is connected with the alternating current driving motor and is used for penetrating into a container to be detected at the current detection position under the microscopic imaging device after the alternating current driving motor finishes the step driving action of the transmission belt of the customized transmission mechanism every time, and performing microscopic picture acquisition on the container to be detected at the current detection position so as to obtain a container internal picture;
a grading processing device connected with the microscopic imaging device and used for sequentially executing contrast improvement processing, statistical ordering filtering processing and filter-based sharpening processing on the received images in the container so as to obtain grading processing images;
the shape matching device is connected with the grading processing device and is used for acquiring each image block corresponding to each virus object in the received grading processing picture based on the virus appearance characteristics, and removing the image blocks with the area smaller than the set area limit in each image block to acquire a plurality of residual image blocks;
the density judging device is connected with the shape matching device and is used for determining corresponding virus distribution density based on the number of the remaining image blocks, and the determined corresponding virus distribution density is positively associated with the number of the remaining image blocks;
the rechecking request device is connected with the density judging device and is used for sending a rechecking request signal when the received virus distribution density is between zero and a set density threshold value and sending a virus clearing signal when the received virus distribution density is zero;
the rechecking request device is also used for sending out a virus detection signal when the received virus distribution density is greater than the set density threshold value.
Second embodiment
Fig. 2 is an internal structural view of a biological detection review request system based on density analysis according to a second embodiment of the present invention.
Unlike fig. 1, the density analysis based bio-detection review request system of fig. 2 may further include the following components:
the alternating current driving motor is used for completing stepping driving action of a transmission belt of the customized transmission mechanism once every set time length so as to switch each container to be detected from the current position of the container to be detected to the position of the container to be detected before the container to be detected;
the customized transmission mechanism comprises a transmission support frame body, a driving wheel, a follower wheel and a transmission belt, and further comprises a groove body container which is fixed on the transmission belt and is uniformly embedded into a plurality of containers to be detected along the advancing direction of the transmission belt;
the microscopic imaging device is connected with the alternating current driving motor and is used for penetrating into a container to be detected at the current detection position under the microscopic imaging device after the alternating current driving motor finishes the step driving action of the transmission belt of the customized transmission mechanism every time, and performing microscopic picture acquisition on the container to be detected at the current detection position so as to obtain a container internal picture;
a grading processing device connected with the microscopic imaging device and used for sequentially executing contrast improvement processing, statistical ordering filtering processing and filter-based sharpening processing on the received images in the container so as to obtain grading processing images;
the shape matching device is connected with the grading processing device and is used for acquiring each image block corresponding to each virus object in the received grading processing picture based on the virus appearance characteristics, and removing the image blocks with the area smaller than the set area limit in each image block to acquire a plurality of residual image blocks;
the density judging device is connected with the shape matching device and is used for determining corresponding virus distribution density based on the number of the remaining image blocks, and the determined corresponding virus distribution density is positively associated with the number of the remaining image blocks;
the rechecking request device is connected with the density judging device and is used for sending a rechecking request signal when the received virus distribution density is between zero and a set density threshold value and sending a virus clearing signal when the received virus distribution density is zero;
the feature storage chip is connected with the shape matching device and is used for storing the virus appearance features and sending the virus appearance features to the shape matching device;
the feature memory chip may be a dynamic memory chip, a static memory chip, or an MMC memory chip, for example.
Third embodiment
Fig. 3 is an internal structural view of a biological detection review request system based on density analysis according to a third embodiment of the present invention.
Unlike fig. 1, the density analysis based bio-detection review request system of fig. 3 may further include the following components:
the alternating current driving motor is used for completing stepping driving action of a transmission belt of the customized transmission mechanism once every set time length so as to switch each container to be detected from the current position of the container to be detected to the position of the container to be detected before the container to be detected;
the customized transmission mechanism comprises a transmission support frame body, a driving wheel, a follower wheel and a transmission belt, and further comprises a groove body container which is fixed on the transmission belt and is uniformly embedded into a plurality of containers to be detected along the advancing direction of the transmission belt;
the microscopic imaging device is connected with the alternating current driving motor and is used for penetrating into a container to be detected at the current detection position under the microscopic imaging device after the alternating current driving motor finishes the step driving action of the transmission belt of the customized transmission mechanism every time, and performing microscopic picture acquisition on the container to be detected at the current detection position so as to obtain a container internal picture;
a grading processing device connected with the microscopic imaging device and used for sequentially executing contrast improvement processing, statistical ordering filtering processing and filter-based sharpening processing on the received images in the container so as to obtain grading processing images;
the shape matching device is connected with the grading processing device and is used for acquiring each image block corresponding to each virus object in the received grading processing picture based on the virus appearance characteristics, and removing the image blocks with the area smaller than the set area limit in each image block to acquire a plurality of residual image blocks;
the density judging device is connected with the shape matching device and is used for determining corresponding virus distribution density based on the number of the remaining image blocks, and the determined corresponding virus distribution density is positively associated with the number of the remaining image blocks;
the rechecking request device is connected with the density judging device and is used for sending a rechecking request signal when the received virus distribution density is between zero and a set density threshold value and sending a virus clearing signal when the received virus distribution density is zero;
the data transmission interface is connected with the rechecking request device and is used for wirelessly transmitting the output data of the rechecking request device to a remote virus recording server.
Next, a further explanation of the specific structure of the biological detection review request system based on density analysis according to the present invention will be continued.
In the biological test review request system based on density analysis shown in accordance with various embodiments of the present invention:
the method for obtaining each image block corresponding to each virus object in the received hierarchical processing picture based on the virus appearance characteristics, and the method for removing the image blocks with the area smaller than the set area limit in each image block to obtain the rest multiple image blocks comprises the following steps: when a certain image block exists in the grading processing picture, the edge shape of the certain image block is matched with the virus shape of the set virus type, and the certain image block is judged to be the image block corresponding to the set virus type object.
In the biological test review request system based on density analysis shown in accordance with various embodiments of the present invention:
the hierarchical processing device comprises a clock generation unit, a primary processing unit, a secondary processing unit and a tertiary processing unit;
wherein, in the hierarchical processing device, the primary processing unit, the secondary processing unit and the tertiary processing unit are sequentially connected;
in the hierarchical processing device, the clock generating unit is respectively connected with the primary processing unit, the secondary processing unit and the tertiary processing unit and is used for respectively providing reference clock signals required by the primary processing unit, the secondary processing unit and the tertiary processing unit;
wherein, in the hierarchical processing device, the primary processing unit is used for executing contrast improvement processing on the received internal picture of the container so as to obtain a signal improvement picture;
wherein, in the hierarchical processing device, the secondary processing unit is used for executing statistical ordering filtering processing on the received signal lifting picture so as to obtain a customized filtering picture;
wherein, in the hierarchical processing device, the three-stage processing unit is configured to perform filter-based sharpening processing on the received custom-filtered picture to obtain a hierarchical processed picture.
And in the biological detection review request system based on density analysis shown in accordance with various embodiments of the present invention:
every set time, finishing the step driving action of the conveying belt of the customized conveying mechanism to switch each container to be detected from the current position to the position of the previous container to be detected, wherein the step driving action comprises the following steps: step-by-step driving action on a transmission belt of the customized transmission mechanism is completed once every set time length, so that a container to be detected is newly arranged at the current detection position, and meanwhile, the detected container at the current detection position is transmitted forwards;
wherein, customization transport mechanism still includes including fixing on the transmission belt and evenly embedding a plurality of cell body containers of waiting to detect the container along transmission belt advancing direction: the groove body container is uniformly provided with a plurality of slotted holes along the advancing direction of the conveying belt, so as to be used for being respectively embedded into a plurality of containers to be detected.
In addition, in the biological detection review request system based on density analysis, obtaining each image block corresponding to each virus object in the received hierarchical processing picture based on the virus appearance feature, and removing the image block with the area smaller than the set area limit amount in each image block to obtain the remaining plurality of image blocks includes: the area of each image block in the received hierarchical processing picture is determined based on the number of pixels that the image block occupies in the received hierarchical processing picture.
The invention has the substantial characteristics and technical effects that:
firstly, analyzing virus distribution density in a microscopic imaging picture in a current container to be detected, so as to send out a re-detection request signal when the analyzed virus distribution density is between zero and a set density threshold value, so as to avoid false detection scenes, and send out a virus detection signal when the virus distribution density is greater than the set density threshold value;
secondly, a targeted picture enhancement mechanism is adopted to sequentially execute contrast enhancement processing, statistical ordering filtering processing and filter-based sharpening processing on microscopic imaging pictures in a current container to be detected, so that the analysis precision of the subsequent virus distribution density is ensured;
and a customized transmission mechanism comprising a transmission support frame body, a driving wheel, a follower wheel and a transmission belt is introduced and used for executing stepping transmission of each container to be detected, so that time-sharing microscopic imaging processing of the containers to be detected one by one is convenient to follow, and the automation level of the whole virus detection mechanism is improved.
In the above, although the present disclosure discusses embodiments of the present invention, the present invention is not limited thereto, but may be variously modified and changed by those skilled in the art to which the present disclosure pertains without departing from the spirit and scope of the present disclosure as claimed in the appended claims.

Claims (10)

1. A biological test review request system based on density analysis, the system comprising:
the alternating current driving motor is used for completing stepping driving action of a transmission belt of the customized transmission mechanism once every set time length so as to switch each container to be detected from the current position of the container to be detected to the position of the container to be detected before the container to be detected;
the customized transmission mechanism comprises a transmission support frame body, a driving wheel, a follower wheel and a transmission belt, and further comprises a groove body container which is fixed on the transmission belt and is uniformly embedded into a plurality of containers to be detected along the advancing direction of the transmission belt;
the microscopic imaging device is connected with the alternating current driving motor and is used for penetrating into a container to be detected at the current detection position under the microscopic imaging device after the alternating current driving motor finishes the step driving action of the transmission belt of the customized transmission mechanism every time, and performing microscopic picture acquisition on the container to be detected at the current detection position so as to obtain a container internal picture;
a grading processing device connected with the microscopic imaging device and used for sequentially executing contrast improvement processing, statistical ordering filtering processing and filter-based sharpening processing on the received images in the container so as to obtain grading processing images;
the shape matching device is connected with the grading processing device and is used for acquiring each image block corresponding to each virus object in the received grading processing picture based on the virus appearance characteristics, and removing the image blocks with the area smaller than the set area limit in each image block to acquire a plurality of residual image blocks;
the density judging device is connected with the shape matching device and is used for determining corresponding virus distribution density based on the number of the remaining image blocks, and the determined corresponding virus distribution density is positively associated with the number of the remaining image blocks;
the rechecking request device is connected with the density judging device and is used for sending a rechecking request signal when the received virus distribution density is between zero and a set density threshold value and sending a virus clearing signal when the received virus distribution density is zero;
the rechecking request device is also used for sending out a virus detection signal when the received virus distribution density is greater than the set density threshold value.
2. The density analysis based bio-detection review request system of claim 1, wherein the system further comprises:
and the feature storage chip is connected with the shape matching device and used for storing the virus appearance features and sending the virus appearance features to the shape matching device.
3. The density analysis based bio-detection review request system of claim 1, wherein the system further comprises:
the data transmission interface is connected with the rechecking request device and is used for wirelessly transmitting the output data of the rechecking request device to a remote virus recording server.
4. A density analysis based bio-detection review request system as claimed in any one of claims 1 to 3, wherein:
the method for obtaining each image block corresponding to each virus object in the received hierarchical processing picture based on the virus appearance characteristics, and the method for removing the image blocks with the area smaller than the set area limit in each image block to obtain the rest multiple image blocks comprises the following steps: when a certain image block exists in the grading processing picture, the edge shape of the certain image block is matched with the virus shape of the set virus type, and the certain image block is judged to be the image block corresponding to the set virus type object.
5. A density analysis based bio-detection review request system as claimed in any one of claims 1 to 3, wherein:
the hierarchical processing device comprises a clock generation unit, a primary processing unit, a secondary processing unit and a tertiary processing unit.
6. The density analysis based bio-detection review request system of claim 5, wherein:
in the hierarchical processing device, the primary processing unit, the secondary processing unit, and the tertiary processing unit are sequentially connected.
7. The density analysis based bio-detection review request system of claim 6, wherein:
in the hierarchical processing device, the clock generation unit is respectively connected with the primary processing unit, the secondary processing unit and the tertiary processing unit and is used for respectively providing reference clock signals required by the primary processing unit, the secondary processing unit and the tertiary processing unit;
in the hierarchical processing device, the primary processing unit is configured to perform contrast enhancement processing on the received container internal picture, so as to obtain a signal enhancement picture.
8. The density analysis based bio-detection review request system of claim 7, wherein:
in the hierarchical processing device, the secondary processing unit is used for performing statistical ordering filtering processing on the received signal lifting picture so as to obtain a customized filtering picture;
wherein, in the hierarchical processing device, the three-stage processing unit is configured to perform filter-based sharpening processing on the received custom-filtered picture to obtain a hierarchical processed picture.
9. A density analysis based bio-detection review request system as claimed in any one of claims 1 to 3, wherein:
every set time, finishing the step driving action of the conveying belt of the customized conveying mechanism to switch each container to be detected from the current position to the position of the previous container to be detected, wherein the step driving action comprises the following steps: and finishing the stepping driving action of the conveying belt of the customized conveying mechanism once every set time so as to newly place the current detection position into a container to be detected, and simultaneously, conveying the detected container at the current detection position forwards.
10. The density analysis based bio-detection review request system of claim 9, wherein:
the customization transport mechanism still includes including fixing on the transmission belt and evenly embedding a plurality of cell body containers of waiting to detect the container along transmission belt advancing direction including: the groove body container is uniformly provided with a plurality of slotted holes along the advancing direction of the conveying belt, so as to be used for being respectively embedded into a plurality of containers to be detected.
CN202211643010.8A 2022-12-20 2022-12-20 Biological detection rechecking request system based on density analysis Pending CN116012313A (en)

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GBGB2307889.2A GB202307889D0 (en) 2022-12-20 2023-05-26 A density analysis based biological detection retest request system

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