CN115971186A - Cleaning and sterilizing process of recyclable and reusable sterile TOTE tank - Google Patents
Cleaning and sterilizing process of recyclable and reusable sterile TOTE tank Download PDFInfo
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- CN115971186A CN115971186A CN202211532192.1A CN202211532192A CN115971186A CN 115971186 A CN115971186 A CN 115971186A CN 202211532192 A CN202211532192 A CN 202211532192A CN 115971186 A CN115971186 A CN 115971186A
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- 238000004140 cleaning Methods 0.000 title claims abstract description 142
- 230000001954 sterilising effect Effects 0.000 title claims abstract description 116
- 238000000034 method Methods 0.000 title claims abstract description 60
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 46
- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 23
- 238000011084 recovery Methods 0.000 claims abstract description 10
- 230000036512 infertility Effects 0.000 claims abstract description 9
- 238000004659 sterilization and disinfection Methods 0.000 claims description 99
- 238000005406 washing Methods 0.000 claims description 49
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 45
- 230000000249 desinfective effect Effects 0.000 claims description 24
- 230000000694 effects Effects 0.000 claims description 13
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 10
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 10
- 239000000645 desinfectant Substances 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 8
- 239000003513 alkali Substances 0.000 claims description 5
- 238000007599 discharging Methods 0.000 claims description 5
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 5
- 239000013589 supplement Substances 0.000 claims description 5
- 239000006188 syrup Substances 0.000 claims description 5
- 235000020357 syrup Nutrition 0.000 claims description 5
- 239000000969 carrier Substances 0.000 abstract 1
- 108010085603 SFLLRNPND Proteins 0.000 description 6
- 239000000047 product Substances 0.000 description 4
- 238000001816 cooling Methods 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 2
- 238000012371 Aseptic Filling Methods 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Images
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W30/00—Technologies for solid waste management
- Y02W30/50—Reuse, recycling or recovery technologies
- Y02W30/80—Packaging reuse or recycling, e.g. of multilayer packaging
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- Apparatus For Disinfection Or Sterilisation (AREA)
Abstract
The invention discloses a cleaning and sterilizing process of a recyclable and reusable sterile TOTE tank, which consists of four parts, namely pre-cleaning, tank cover and accessory disassembling and cleaning and sterilizing, CIP cleaning and SIP sterilizing, wherein the four parts comprise a high-pressure cleaning gun, a TOTE tank, a cleaning and sterilizing pool, CIP cleaning equipment, a CIP recovery pump, an SIP sterilizing device, a nitrogen filter, a steam filter and a steam trap. The cleaning and sterilizing process of the recyclable sterile TOTE tank is a process for cleaning and sterilizing the recyclable sterile TOTE tank, can ensure the sterility and the safety of the TOTE tank, can well convey qualified products to customers safely, ensures the reusability of carriers of the products, and saves the transportation cost.
Description
Technical Field
The invention relates to the technical field of jam product transportation carrier processing, in particular to a cleaning and sterilizing process of a recyclable and reusable sterile TOTE tank.
Background
The prior aseptic filling jam adopts a packaging form of a PP aseptic bag covered with an aluminum foil, and is characterized by disposable use, high price, great waste for industrial customers with large use amount and increased cost. Based on this, a repeatedly usable TOTE aseptic tank breeds, and TOTE aseptic tank is stainless steel aseptic tank, and this TOTE aseptic tank divide into two kinds of specifications 800L and 400L, has satisfied industry customer's demand to can used repeatedly, thereby practiced thrift both sides ' enterprise's production and packaging cost greatly.
The cleaning and sterilizing process disclosed by the invention is formed by cleaning and sterilizing the sterile TOTE tank. The process can ensure the sterility and safety of the TOTE tank and can well and safely convey qualified products to customers.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a cleaning and sterilizing process of a recyclable and reusable sterile TOTE tank, which can ensure the sterility and the safety of a jam product transportation carrier, ensure the reutilization of the carrier and save the transportation cost.
(II) technical scheme
In order to realize the purpose, the invention is realized by the following technical scheme: the utility model provides a recoverable used repeatedly aseptic TOTE jar washs sterilization process, whole this washing sterilization process comprises four parts of precleaning, cover and accessory are torn open and are washed the disinfection, CIP washing and SIP sterilization, and the unit of its four parts includes high pressure cleaning gun, TOTE jar, cleaning and disinfecting pond, CIP cleaning equipment, CIP recovery pump, SIP sterilizing equipment, nitrogen filter, steam filter and steam trap, should wash sterilization process specifically includes the following step:
s1, pre-cleaning the recovered dirty TOTE tank from outside to inside by a high-pressure cleaning gun;
s2, putting the detached tank cover and the accessory parts of the tank cover into a cleaning area in a cleaning and disinfecting tank, cleaning, and then transferring the tank cover and the accessory parts of the tank cover into a disinfecting area in the cleaning and disinfecting tank to soak and disinfect;
s3, placing the TOTE tank subjected to pre-cleaning on a cleaning station of CIP cleaning equipment, cleaning the TOTE tank by the CIP five-step cleaning method according to set programs and parameters by the CIP cleaning equipment, and recovering the cleaning liquid to the CIP cleaning equipment by a CIP recovery pump to ensure the cleaning effect;
s4, the TOTE tank after the CIP cleaning is finished is placed at an SIP sterilization station, a tank cover and accessory spare parts are installed, and waiting for sterilization is carried out, and before the TOTE tank is sterilized, an SIP sterilization device carries out steam sterilization on a steam pipeline, a nitrogen pipeline, a steam filter and a nitrogen filter of the TOTE tank, so that the sterility of a connecting pipeline is ensured;
s5, performing steam sterilization on the TOTE tank by the SIP sterilization device according to a set program and set parameters, and discharging steam condensate water generated during sterilization by a steam trap to ensure the sterilization effect;
s6, when steam sterilization is finished, the system can supplement nitrogen to the TOTE tank, cool and maintain pressure of the TOTE tank, and the positive pressure of the TOTE tank is always kept;
and S7, after the sterilization is finished, placing the TOTE tank in a 24-hour pressure maintaining area, detecting the pressure value at regular time, and producing for later use after the pressure value is detected to be qualified.
Preferably, the pressure of the positive pressure of the TOTE tank is always maintained at 0.8-1bar in the step S6.
Preferably, the parameters set by the SIP sterilization apparatus in step S5 include a temperature parameter, a time parameter, and a pressure parameter.
Preferably, the parameters set by the CIP cleaning apparatus in step S3 include a temperature parameter, a time parameter, a concentration parameter, and a flow parameter.
Preferably, the working pressure of the high-pressure cleaning gun in the step S1 is 0.8-1.6MPa.
Preferably, the disinfectant in the disinfection area of the cleaning and disinfection tank in the step S2 is 2-3% hydrogen peroxide disinfectant.
Preferably, the five-step CIP cleaning method in the step S3 specifically comprises the following steps:
t1, primary water washing: firstly, feeding hot water of 50-60 ℃ into a system, and washing the TOTE tank sterilized in the step S2 until residual syrup is removed;
t2, alkali washing: injecting 2-3% sodium carbonate solution, controlling water temperature at 50-60 deg.C, continuously cleaning TOTE tank, and cleaning liquid circulation time of 10min to obtain effective cleaning effect;
t3, secondary water washing: rinsing with sufficient water until the rinse is completely removed;
t4, sterilization: cleaning the TOTE tank with hot water at 85 ℃ for 15 minutes;
t5, washing for three times: the equipment should be cooled down gradually, after having been disinfected with hot water, with the aid of fully treated water, in order not to cause damage.
Preferably, the temperature for steam sterilization in the step S6 is 130 to 180 ℃.
(III) advantageous effects
The invention provides a cleaning and sterilizing process of a recyclable and reusable sterile TOTE tank. Compared with the prior art, the method has the following beneficial effects: the invention relates to a cleaning and sterilizing process of a recyclable and reusable sterile TOTE tank, which comprises four parts of pre-cleaning, tank cover and accessory disassembling and cleaning and sterilizing, CIP cleaning and SIP sterilizing, wherein the four parts comprise a high-pressure cleaning gun, a TOTE tank, a cleaning and sterilizing tank, CIP cleaning equipment, a CIP recovery pump, an SIP sterilizing device, a nitrogen filter, a steam filter and a steam drain valve.
Drawings
FIG. 1 is a flow chart of the present invention;
in the figure, 1TOTE tank, 2 high pressure cleaning gun, 3 cleaning disinfection pool, 4CIP cleaning equipment, 5CIP recovery pump, 6SIP sterilization device, 7 nitrogen filter, 8 steam filter and 9 steam trap.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, the embodiment of the present invention provides three technical solutions: a cleaning and sterilizing process of a recyclable and reusable sterile TOTE tank specifically comprises the following embodiments:
example 1
The utility model provides a recoverable used repeatedly aseptic TOTE jar washs sterilization process, whole this washing sterilization process comprises four parts of precleaning, cover and accessory are torn open and are washed the disinfection, CIP washs and SIP sterilization, the unit of its four parts includes high pressure cleaning gun 2, TOTE jar 1, wash disinfection pond 3, CIP cleaning equipment 4, CIP recycle pump 5, SIP sterilizing equipment 6, nitrogen filter 7, steam filter 8 and steam trap 9, this washing sterilization process specifically includes following step:
s1, pre-cleaning the recovered dirty TOTE tank 1 from outside to inside by a high-pressure cleaning gun 2, wherein the working pressure of the high-pressure cleaning gun 2 is 1.2MPa;
s2, the removed tank cover and accessory parts of the tank cover are put into a cleaning area in a cleaning and disinfecting tank 3 to be cleaned, and then the tank cover and the accessory parts of the tank cover are transferred into a disinfecting area of the cleaning and disinfecting tank 3 to be soaked and disinfected, wherein the disinfecting liquid in the disinfecting area of the cleaning and disinfecting tank 3 is 2.5% of hydrogen peroxide disinfectant;
s3, place the cleaning station at CIP cleaning equipment 4 at TOTE jar 1 that washs the completion in advance, CIP cleaning equipment 4 adopts CIP' S five steps cleaning method to wash TOTE jar 1 according to set-up procedure and parameter, and CIP recovery pump 5 is responsible for retrieving the washing liquid to CIP cleaning equipment 4, guarantees its cleaning performance, and the parameter of setting includes temperature parameter, time parameter, concentration parameter and flow parameter, and CIP five steps cleaning method specifically includes following steps:
t1, primary water washing: firstly, feeding hot water of 55 ℃ into a system, and washing the TOTE tank 1 sterilized in the step S2 until residual syrup is removed;
t2, alkali washing: injecting 2.5% sodium carbonate solution, controlling water temperature at 55 deg.C, continuously cleaning TOTE tank 1, and cleaning solution circulation time of 10min to obtain effective cleaning effect;
t3, secondary water washing: rinsing with sufficient water until the rinse is completely removed;
t4, sterilization: the time for washing the TOTE tank 1 with hot water at 85 ℃ is 15 minutes;
t5, washing for three times: washing with fully treated water, and gradually cooling the equipment after hot water sterilization is performed to avoid damage;
s4, the TOTE tank 1 after the CIP cleaning is finished is placed at an SIP sterilization station, a tank cover and accessory spare parts are installed, and waiting for sterilization is carried out, and the SIP sterilization device 6 carries out steam sterilization on a steam pipeline, a nitrogen pipeline, a steam filter and a nitrogen filter of the TOTE tank 1 before sterilizing the TOTE tank 1, so that the sterility of a connecting pipeline is ensured;
s5, performing steam sterilization on the TOTE tank 1 by the SIP sterilization device 6 according to set programs and parameters, discharging steam condensate water generated during sterilization by the steam trap 9 to ensure the sterilization effect, wherein the set parameters comprise temperature parameters, time parameters and pressure parameters;
s6, when steam sterilization is finished, the system can supplement nitrogen to the TOTE tank 1, cool and maintain the pressure of the TOTE tank 1, the positive pressure is always kept at 0.9bar, and the steam sterilization temperature is 150 ℃;
and S7, after the sterilization is finished, placing the TOTE tank 1 in a 24-hour pressure maintaining area, detecting the pressure value at regular time, and producing for later use after the pressure value is detected to be qualified.
Example 2
The utility model provides a recoverable used repeatedly aseptic TOTE jar washs sterilization process, whole this washing sterilization process comprises four parts of precleaning, cover and accessory are torn open and are washed the disinfection, CIP washs and SIP sterilization, the unit of its four parts includes high pressure cleaning gun 2, TOTE jar 1, wash disinfection pond 3, CIP cleaning equipment 4, CIP recycle pump 5, SIP sterilizing equipment 6, nitrogen filter 7, steam filter 8 and steam trap 9, this washing sterilization process specifically includes following step:
s1, pre-cleaning the recovered dirty TOTE tank 1 from outside to inside by a high-pressure cleaning gun 2, wherein the working pressure of the high-pressure cleaning gun 2 is 0.8MPa;
s2, the removed tank cover and the tank cover accessory parts are put into a cleaning area in a cleaning and disinfecting tank 3 to be cleaned, and then the tank cover and the tank cover accessory parts are transferred into a disinfecting area in the cleaning and disinfecting tank 3 to be soaked and disinfected, and the disinfectant in the disinfecting area in the cleaning and disinfecting tank 3 is 2% hydrogen peroxide disinfectant;
s3, place the cleaning station at CIP cleaning equipment 4 at TOTE jar 1 that washs the completion in advance, CIP cleaning equipment 4 adopts CIP' S five steps cleaning method to wash TOTE jar 1 according to set-up procedure and parameter, and CIP recovery pump 5 is responsible for retrieving the washing liquid to CIP cleaning equipment 4, guarantees its cleaning performance, and the parameter of setting includes temperature parameter, time parameter, concentration parameter and flow parameter, and CIP five steps cleaning method specifically includes following steps:
t1, primary water washing: firstly, feeding hot water of 50 ℃ into a system, and washing the TOTE tank 1 sterilized in the step S2 until residual syrup is removed;
t2, alkali washing: injecting 2% sodium carbonate solution, controlling water temperature at 50 deg.C, continuously cleaning TOTE tank 1, and cleaning solution circulation time of 10min to obtain effective cleaning effect;
t3, secondary water washing: rinsing with sufficient water until the rinse is completely removed;
t4, sterilization: the time for washing the TOTE tank 1 with hot water at 85 ℃ is 15 minutes;
t5, washing for three times: washing with fully treated water, and gradually cooling the equipment after hot water sterilization is performed to avoid damage;
s4, the TOTE tank 1 after the CIP cleaning is finished is placed at an SIP sterilization station, a tank cover and accessory spare parts are installed, and waiting for sterilization is carried out, and the SIP sterilization device 6 carries out steam sterilization on a steam pipeline, a nitrogen pipeline, a steam filter and a nitrogen filter of the TOTE tank 1 before sterilizing the TOTE tank 1, so that the sterility of a connecting pipeline is ensured;
s5, performing steam sterilization on the TOTE tank 1 by the SIP sterilization device 6 according to set programs and parameters, discharging steam condensate water generated during sterilization by the steam trap 9 to ensure the sterilization effect, wherein the set parameters comprise temperature parameters, time parameters and pressure parameters;
s6, when steam sterilization is finished, the system can supplement nitrogen to the TOTE tank 1, cool and maintain the pressure of the TOTE tank 1, the positive pressure is always kept at 0.8bar, and the steam sterilization temperature is 130-180 ℃;
and S7, after the sterilization is finished, placing the TOTE tank 1 in a 24-hour pressure maintaining area, detecting the pressure value at regular time, and producing for later use after the pressure value is detected to be qualified.
Example 3
The utility model provides a recoverable used repeatedly aseptic TOTE jar washs sterilization process, whole this washing sterilization process comprises four parts of precleaning, cover and accessory are torn open and are washed the disinfection, CIP washs and SIP sterilization, the unit of its four parts includes high pressure cleaning gun 2, TOTE jar 1, wash disinfection pond 3, CIP cleaning equipment 4, CIP recycle pump 5, SIP sterilizing equipment 6, nitrogen filter 7, steam filter 8 and steam trap 9, this washing sterilization process specifically includes following step:
s1, pre-cleaning the recovered dirty TOTE tank 1 from outside to inside by a high-pressure cleaning gun 2, wherein the working pressure of the high-pressure cleaning gun 2 is 1.6MPa;
s2, the removed tank cover and the tank cover accessory parts are put into a cleaning area in a cleaning and disinfecting tank 3 to be cleaned, and then the tank cover and the tank cover accessory parts are transferred into a disinfecting area in the cleaning and disinfecting tank 3 to be soaked and disinfected, and the disinfectant in the disinfecting area in the cleaning and disinfecting tank 3 is hydrogen peroxide disinfectant with the concentration of 3%;
s3, place the cleaning station at CIP cleaning equipment 4 at TOTE jar 1 that washs the completion in advance, CIP cleaning equipment 4 adopts CIP' S five steps cleaning method to wash TOTE jar 1 according to set-up procedure and parameter, and CIP recovery pump 5 is responsible for retrieving the washing liquid to CIP cleaning equipment 4, guarantees its cleaning performance, and the parameter of setting includes temperature parameter, time parameter, concentration parameter and flow parameter, and CIP five steps cleaning method specifically includes following steps:
t1, primary water washing: firstly, feeding hot water of 60 ℃ into a system, and washing the TOTE tank 1 sterilized in the step S2 until residual syrup is removed;
t2, alkali washing: injecting 3% sodium carbonate solution, controlling the water temperature at 60 ℃, continuously cleaning the TOTE tank 1, and achieving effective cleaning effect when the circulation time of the cleaning solution is 10 min;
t3, secondary water washing: rinsing with sufficient water until the rinse is completely removed;
t4, sterilization: the time for washing the TOTE tank 1 with hot water at 85 ℃ is 15 minutes;
t5, washing for three times: washing with fully treated water, and gradually cooling the equipment after hot water sterilization is performed to avoid damage;
s4, the TOTE tank 1 after the CIP cleaning is finished is placed at an SIP sterilization station, a tank cover and accessories are installed, and waiting for sterilization, and before the TOTE tank 1 is sterilized, an SIP sterilization device 6 performs steam sterilization on a steam pipeline, a nitrogen pipeline, a steam filter and a nitrogen filter of the TOTE tank 1to ensure the sterility of a connecting pipeline;
s5, performing steam sterilization on the TOTE tank 1 by the SIP sterilization device 6 according to set programs and parameters, discharging steam condensate water generated during sterilization by the steam trap 9 to ensure the sterilization effect, wherein the set parameters comprise temperature parameters, time parameters and pressure parameters;
s6, when steam sterilization is finished, the system can supplement nitrogen to the TOTE tank 1, cool and maintain the pressure of the TOTE tank 1, the positive pressure is kept at 1bar all the time, and the steam sterilization temperature is 130-180 ℃;
and S7, after the sterilization is finished, placing the TOTE tank 1 in a 24-hour pressure maintaining area, detecting the pressure value at regular time, and producing for later use after the pressure value is detected to be qualified.
In summary, the invention is a process for cleaning and sterilizing the recycled sterile TOTE tank, which can ensure the sterility and safety of the TOTE tank, can well and safely convey the qualified products to customers, ensures the reusability of the carrier, and saves the transportation cost.
And those not described in detail in this specification are well within the skill of those in the art.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. A cleaning and sterilizing process of a recyclable sterile TOTE tank is characterized in that: whole this washing sterilization process comprises four parts of precleaning, cover and accessory are torn open and are washed disinfection, CIP washing and SIP sterilization, and the unit of its four parts includes high pressure cleaning gun (2), TOTE jar (1), cleaning and disinfecting pond (3), CIP cleaning equipment (4), CIP recovery pump (5), SIP sterilization apparatus (6), nitrogen filter (7), steam filter (8) and steam trap (9), should wash sterilization process specifically includes following step:
s1, pre-cleaning the recovered dirty TOTE tank (1) from outside to inside through a high-pressure cleaning gun (2);
s2, the removed tank cover and the auxiliary accessories of the tank cover are put into a cleaning area in a cleaning and disinfecting tank (3) to be cleaned, and then the tank cover and the auxiliary accessories are transferred into a disinfecting area of the cleaning and disinfecting tank (3) to be soaked and disinfected;
s3, the TOTE tank (1) which is pre-cleaned is placed on a cleaning station of a CIP cleaning device (4), the TOTE tank (1) is cleaned by the CIP cleaning device (4) according to a set program and parameters by adopting a CIP five-step cleaning method, and a CIP recovery pump (5) is responsible for recovering cleaning liquid to the CIP cleaning device (4) to ensure the cleaning effect;
s4, the TOTE tank (1) after the CIP cleaning is finished is placed at an SIP sterilization station, a tank cover and accessory spare parts are installed, the sterilization is waited, and an SIP sterilization device (6) performs steam sterilization on a steam pipeline, a nitrogen pipeline, a steam filter and a nitrogen filter of the TOTE tank (1) before the TOTE tank (1) is sterilized, so that the sterility of a connecting pipeline is guaranteed;
s5, performing steam sterilization on the TOTE tank (1) by the SIP sterilization device (6) according to a set program and parameters, and discharging steam condensate water generated during sterilization by a steam trap (9) to ensure the sterilization effect;
s6, when steam sterilization is finished, the system can supplement nitrogen to the TOTE tank (1), cool and maintain pressure of the TOTE tank, and keep the positive pressure of the TOTE tank (1) all the time;
and S7, after the sterilization is finished, placing the TOTE tank (1) in a 24-hour pressure maintaining area, detecting the pressure value at regular time, and producing for later use after the pressure value is detected to be qualified.
2. The process of claim 1, wherein the TOTE tank is sterilized by washing with the following sterilized TOTE tank, and the process further comprises: and in the step S6, the positive pressure of the TOTE tank (1) is always kept at 0.8-1bar.
3. The process of claim 1, wherein the TOTE tank is sterilized by washing with the following sterilized TOTE tank, and the process further comprises: the parameters set by the SIP sterilization device (6) in the step S5 comprise a temperature parameter, a time parameter and a pressure parameter.
4. The process of claim 1, wherein the TOTE tank is sterilized by washing with the following sterilized TOTE tank, and the process further comprises: the parameters set by the CIP cleaning equipment (4) in the step S3 comprise a temperature parameter, a time parameter, a concentration parameter and a flow parameter.
5. The process of claim 1, wherein the cleaning and sterilizing process comprises the steps of: and the working pressure of the high-pressure cleaning gun (2) in the step S1 is 0.8-1.6MPa.
6. The process of claim 1, wherein the TOTE tank is sterilized by washing with the following sterilized TOTE tank, and the process further comprises: in the step S2, 2-3% of hydrogen peroxide disinfectant is adopted as disinfectant in the disinfection area of the cleaning and disinfection tank (3).
7. The process of claim 1, wherein the TOTE tank is sterilized by washing with the following sterilized TOTE tank, and the process further comprises: the CIP five-step cleaning method in the step S3 specifically comprises the following steps:
t1, primary water washing: firstly, feeding hot water of 50-60 ℃ into a system, and washing the TOTE tank (1) sterilized in the step S2 until residual syrup is removed;
t2, alkali washing: injecting 2-3% sodium carbonate solution, controlling water temperature at 50-60 deg.C, continuously cleaning TOTE tank (1), and cleaning liquid circulation time of 10min to obtain effective cleaning effect;
t3, secondary water washing: rinsing with sufficient water until the rinse is completely removed;
t4, sterilization: cleaning the TOTE tank (1) with hot water at 85 ℃ for 15 minutes;
t5, washing for three times: the equipment should be cooled down gradually, after having been disinfected with hot water, with the aid of fully treated water, in order not to cause damage.
8. The process of claim 1, wherein the cleaning and sterilizing process comprises the steps of: the temperature of the steam sterilization in the step S6 is 130-180 ℃.
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| CN202211532192.1A CN115971186A (en) | 2022-12-01 | 2022-12-01 | Cleaning and sterilizing process of recyclable and reusable sterile TOTE tank |
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| CN202211532192.1A CN115971186A (en) | 2022-12-01 | 2022-12-01 | Cleaning and sterilizing process of recyclable and reusable sterile TOTE tank |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117100894A (en) * | 2023-10-25 | 2023-11-24 | 山东新华医疗器械股份有限公司 | Terminal continuous sterilization system and method applied to sterile preparation production |
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